CA9 (carbonic anhydrase 9) - Rat Genome Database

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Gene: CA9 (carbonic anhydrase 9) Canis lupus familiaris
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Symbol: CA9
Name: carbonic anhydrase 9
RGD ID: 12343543
Description: ENCODES a protein that exhibits zinc ion binding (inferred); INVOLVED IN morphogenesis of an epithelium (ortholog); response to drug (ortholog); response to hypoxia (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; ASSOCIATED WITH Anaplasia (ortholog); Anauxetic Dysplasia (ortholog); breast carcinoma (ortholog); FOUND IN basolateral plasma membrane (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: INFERRED
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11152,205,619 - 52,211,281 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1152,205,668 - 52,211,267 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1150,773,252 - 50,778,851 (+)NCBI
ROS_Cfam_1.01153,270,515 - 53,276,220 (+)NCBI
UMICH_Zoey_3.11151,815,201 - 51,820,803 (+)NCBI
UNSW_CanFamBas_1.01151,798,686 - 51,804,281 (+)NCBI
UU_Cfam_GSD_1.01152,500,820 - 52,506,421 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22170054   PMID:26906567  


Genomics

Comparative Map Data
CA9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11152,205,619 - 52,211,281 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1152,205,668 - 52,211,267 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1150,773,252 - 50,778,851 (+)NCBI
ROS_Cfam_1.01153,270,515 - 53,276,220 (+)NCBI
UMICH_Zoey_3.11151,815,201 - 51,820,803 (+)NCBI
UNSW_CanFamBas_1.01151,798,686 - 51,804,281 (+)NCBI
UU_Cfam_GSD_1.01152,500,820 - 52,506,421 (+)NCBI
CA9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl935,673,918 - 35,681,159 (+)EnsemblGRCh38hg38GRCh38
GRCh38935,673,809 - 35,681,159 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37935,673,925 - 35,681,156 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36935,663,915 - 35,671,152 (+)NCBINCBI36hg18NCBI36
Build 34935,663,914 - 35,671,152NCBI
Celera935,607,463 - 35,614,702 (+)NCBI
Cytogenetic Map9p13.3NCBI
HuRef935,629,523 - 35,636,764 (+)NCBIHuRef
CHM1_1935,673,743 - 35,680,984 (+)NCBICHM1_1
Car9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39443,507,026 - 43,513,729 (+)NCBIGRCm39mm39
GRCm39 Ensembl443,506,966 - 43,513,729 (+)Ensembl
GRCm38443,507,026 - 43,513,729 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl443,506,966 - 43,513,729 (+)EnsemblGRCm38mm10GRCm38
MGSCv37443,519,898 - 43,526,597 (+)NCBIGRCm37mm9NCBIm37
MGSCv36443,528,107 - 43,534,829 (+)NCBImm8
Celera443,540,895 - 43,547,584 (+)NCBICelera
Cytogenetic Map4A5NCBI
Ca9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2557,763,234 - 57,769,838 (+)NCBI
Rnor_6.0 Ensembl559,008,933 - 59,015,528 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0559,008,277 - 59,015,535 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0563,533,527 - 63,540,129 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4559,986,413 - 59,993,015 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1559,986,589 - 59,992,484 (+)NCBI
Celera556,343,808 - 56,350,416 (+)NCBICelera
Cytogenetic Map5q22NCBI
Ca9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955472619,245 - 625,051 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955472619,084 - 625,570 (-)NCBIChiLan1.0ChiLan1.0
CA9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1936,328,205 - 36,335,474 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl936,328,303 - 36,335,340 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0935,525,877 - 35,533,159 (+)NCBIMhudiblu_PPA_v0panPan3
Ca9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947167,124,669 - 167,131,057 (+)NCBI
SpeTri2.0NW_0049365243,672,393 - 3,678,630 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CA9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1236,388,690 - 236,400,822 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11236,393,727 - 236,400,994 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21264,118,816 - 264,126,024 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CA9
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11244,921,530 - 44,929,504 (-)NCBI
ChlSab1.1 Ensembl1244,921,665 - 44,928,831 (-)Ensembl
Ca9
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248685,110,602 - 5,131,167 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 3 1 8 3
Low 5 5 14 1 6 1 5 6 12 7 6
Below cutoff 5 5 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000003289   ⟹   ENSCAFP00000003055
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1152,205,668 - 52,211,267 (+)Ensembl
RefSeq Acc Id: NM_001145174   ⟹   NP_001138646
RefSeq Status: INFERRED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11152,205,668 - 52,211,267 (+)NCBI
Dog10K_Boxer_Tasha1150,773,252 - 50,778,851 (+)NCBI
ROS_Cfam_1.01153,270,614 - 53,276,220 (+)NCBI
UMICH_Zoey_3.11151,815,201 - 51,820,803 (+)NCBI
UNSW_CanFamBas_1.01151,798,686 - 51,804,281 (+)NCBI
UU_Cfam_GSD_1.01152,500,820 - 52,506,421 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022424930   ⟹   XP_022280638
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11152,205,626 - 52,211,281 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022424931   ⟹   XP_022280639
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11152,205,619 - 52,211,281 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002631076
RefSeq Status:
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11152,205,625 - 52,211,088 (+)NCBI
Sequence:
RefSeq Acc Id: XR_005434148
RefSeq Status:
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01153,270,515 - 53,276,028 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001138646 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001138646   ⟸   NM_001145174
- UniProtKB: E2RAI4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022280639   ⟸   XM_022424931
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_022280638   ⟸   XM_022424930
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSCAFP00000003055   ⟸   ENSCAFT00000003289
Protein Domains
Alpha-carbonic anhydrase

Promoters
RGD ID:13685249
Promoter ID:EPDNEW_C3317
Type:initiation region
Name:CA9_1
Description:carbonic anhydrase 9
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11152,205,633 - 52,205,693EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000002077 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000003055 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000003289 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.10.200.10 UniProtKB/TrEMBL
InterPro CA9 UniProtKB/TrEMBL
  Carbonic_anhydrase_a UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class_CS UniProtKB/TrEMBL
  Carbonic_anhydrase_a_sf UniProtKB/TrEMBL
KEGG Report cfa:611933 UniProtKB/TrEMBL
NCBI Gene CA9 ENTREZGENE
PANTHER PTHR18952 UniProtKB/TrEMBL
  PTHR18952:SF18 UniProtKB/TrEMBL
Pfam Carb_anhydrase UniProtKB/TrEMBL
PROSITE ALPHA_CA_1 UniProtKB/TrEMBL
  ALPHA_CA_2 UniProtKB/TrEMBL
SMART Carb_anhydrase UniProtKB/TrEMBL
Superfamily-SCOP SSF51069 UniProtKB/TrEMBL
UniProt E2RAI4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:38617 ENTREZGENE