TLR2 (toll like receptor 2) - Rat Genome Database

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Gene: TLR2 (toll like receptor 2) Chlorocebus sabaeus
Analyze
Symbol: TLR2
Name: toll like receptor 2
RGD ID: 18684616
Description: ENCODES a protein that exhibits diacyl lipopeptide binding (ortholog); lipopeptide binding (ortholog); lipoteichoic acid binding (ortholog); INVOLVED IN cell surface pattern recognition receptor signaling pathway (ortholog); cellular response to bacterial lipopeptide (ortholog); cellular response to diacyl bacterial lipopeptide (ortholog); PARTICIPATES IN Toll-like receptor signaling pathway; ASSOCIATED WITH abdominal obesity-metabolic syndrome 1 (ortholog); acne (ortholog); acute kidney failure (ortholog); FOUND IN cell body (ortholog); cell projection (ortholog); cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC103236415; toll-like receptor 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17100,239,533 - 100,565,955 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7100,258,441 - 100,260,795 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603779,891,761 - 79,956,832 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 20 of 238 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
TLR2Green Monkeyabdominal obesity-metabolic syndrome 1 susceptibilityISOTlr2 (Mus musculus)9068941 RGDPMID:19841034 and REF_RGD_ID:15090861
TLR2Green Monkeyacne susceptibilityISOTLR2 (Homo sapiens)9068941DNA:polymorphism:cds:p.R753Q(human)RGDPMID:20861605 and REF_RGD_ID:8553023
TLR2Green Monkeyacne  ISOTLR2 (Homo sapiens)9068941mRNA and protein:increased expression:skin:RGDPMID:18241264 and REF_RGD_ID:8553025
TLR2Green Monkeyacne severityISOTLR2 (Homo sapiens)9068941 RGDPMID:20726329 and REF_RGD_ID:8553024
TLR2Green Monkeyacute kidney failure  ISOTlr2 (Mus musculus)9068941associated with SepsisRGDPMID:22655058 and REF_RGD_ID:7207898
TLR2Green MonkeyAcute Lung Injury treatmentISOTlr2 (Rattus norvegicus)9068941associated with EndotoxemiaRGDPMID:22982561 and REF_RGD_ID:7204498
TLR2Green MonkeyAcute Lung Injury treatmentISOTlr2 (Rattus norvegicus)9068941 RGDPMID:23428646 more ...
TLR2Green Monkeyacute necrotizing pancreatitis  ISOTlr2 (Rattus norvegicus)9068941mRNA:increased expression:liverRGDPMID:16524509 and REF_RGD_ID:2312724
TLR2Green MonkeyAcute Tubulointerstitial Nephritis  ISOTlr2 (Mus musculus)9068941 RGDPMID:22194975 and REF_RGD_ID:7207900
TLR2Green Monkeyalcohol dependence  ISOTLR2 (Homo sapiens)9068941protein:increased expression:orbitofrontal cortex RGDPMID:23206318 and REF_RGD_ID:7175526
TLR2Green Monkeyalcohol use disorder  ISOTLR2 (Homo sapiens)9068941protein:decreased expression:blood and monocyteRGDPMID:27256567 and REF_RGD_ID:597538485
TLR2Green Monkeyalcohol use disorder  ISOTLR2 (Homo sapiens)9068941mRNA:increased expression:orbitofrontal cortexRGDPMID:34415075 and REF_RGD_ID:597538499
TLR2Green Monkeyalcohol use disorder  ISOTlr2 (Rattus norvegicus)9068941protein:decreased expression:alveolar macrophageRGDPMID:36281822 and REF_RGD_ID:597538461
TLR2Green Monkeyalcohol use disorder  ISOTlr2 (Rattus norvegicus)9068941mRNA:increased expression:liverRGDPMID:30756376 and REF_RGD_ID:597538493
TLR2Green Monkeyalcohol use disorder  ISOTLR2 (Homo sapiens)9068941mRNA:increased expression:respiratory system fluid/secretionRGDPMID:26208141 and REF_RGD_ID:11342768
TLR2Green Monkeyalcohol withdrawal syndrome  ISOTLR2 (Homo sapiens)9068941mRNA:increased expression:blood and monocyteRGDPMID:37058088 and REF_RGD_ID:597538488
TLR2Green MonkeyAlcohol-Related Disorders treatmentISOTlr2 (Mus musculus)9068941 RGDPMID:26226164 and REF_RGD_ID:597538484
TLR2Green Monkeyalcoholic liver cirrhosis  ISOTLR2 (Homo sapiens)9068941protein:increased expression:blood and neutrophilRGDPMID:18433921 and REF_RGD_ID:5130706
TLR2Green MonkeyAlcoholic Liver Diseases treatmentISOTlr2 (Mus musculus)9068941 RGDPMID:30353422 and REF_RGD_ID:597538498
TLR2Green MonkeyAlcoholic Liver Diseases  ISOTlr2 (Mus musculus)9068941mRNA:increased expression:liverRGDPMID:16628628 and REF_RGD_ID:597538497
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Original Reference(s)
TLR2Green Monkeycolorectal cancer  ISOTLR2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 and PMID:28492532
TLR2Green MonkeyCOVID-19  ISOTLR2 (Homo sapiens)8554872ClinVar Annotator: match by term: COVID-19–associated multisystem inflammatory syndrome in adultsClinVar 
TLR2Green Monkeyleprosy  ISOTLR2 (Homo sapiens)8554872ClinVar Annotator: match by term: Leprosy more ...ClinVarPMID:11476982 more ...
TLR2Green Monkeytuberculosis  ISOTLR2 (Homo sapiens)8554872ClinVar Annotator: match by term: Mycobacterium tuberculosis and susceptibility toClinVarPMID:14979495 more ...
1 to 18 of 18 rows
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Original Reference(s)
TLR2Green Monkeyacute kidney failure  ISOTLR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:29286200
TLR2Green MonkeyBacterial Eye Infections  ISOTLR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:23661603
TLR2Green MonkeyBrain Injuries  ISOTLR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:21549006
TLR2Green Monkeycardiomyopathy  ISOTLR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:15505089
TLR2Green MonkeyCardiotoxicity  ISOTLR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:29959987
TLR2Green Monkeycholestasis  ISOTLR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:27989131
TLR2Green MonkeyColorectal Neoplasms  ISOTLR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16879199 and PMID:17892325
TLR2Green Monkeycongestive heart failure  ISOTLR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:29959987
TLR2Green MonkeyDrug-Related Side Effects and Adverse Reactions  ISOTLR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:18466103 and PMID:31557154
TLR2Green MonkeyEosinophilia  ISOTLR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:26882889
TLR2Green Monkeyessential hypertension  ISOTLR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:34453990
TLR2Green MonkeyInflammation  ISOTLR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:22178603
TLR2Green Monkeykeratitis  ISOTLR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:23661603
TLR2Green Monkeymite infestation  ISOTLR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:29253318
TLR2Green Monkeymyelodysplastic syndrome  ISOTLR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:28963909
TLR2Green MonkeyReperfusion Injury  ISOTLR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:25780291
TLR2Green Monkeyrheumatoid arthritis  ISOTLR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:19192274
TLR2Green MonkeyStaphylococcal Infections  ISOTLR2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:23661603
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Original Reference(s)
TLR2Green Monkeycolorectal cancer susceptibilityISOTLR2 (Homo sapiens)7240710 OMIM 
TLR2Green Monkeyleprosy susceptibilityISOTLR2 (Homo sapiens)7240710 OMIM 
TLR2Green Monkeytuberculosis susceptibilityISOTLR2 (Homo sapiens)7240710 OMIM 


Biological Process
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Original Reference(s)
TLR2Green Monkeycell surface pattern recognition receptor signaling pathway acts_upstream_of_or_withinISOMGI:21786759068941 PMID:12719478MGIPMID:12719478
TLR2Green Monkeycellular response to bacterial lipopeptide acts_upstream_of_or_withinISOMGI:26740369068941 PMID:15690042MGIPMID:15690042
TLR2Green Monkeycellular response to bacterial lipopeptide involved_inISOTlr2 (Mus musculus)9068941 PMID:15356140BHF-UCLPMID:15356140
TLR2Green Monkeycellular response to diacyl bacterial lipopeptide involved_inISOTLR2 (Homo sapiens)9068941 PMID:16880211UniProtPMID:16880211
TLR2Green Monkeycellular response to diacyl bacterial lipopeptide acts_upstream_of_or_withinIEAUniProtKB:O60603 and ensembl:ENSP00000494425150520179 EnsemblGO_REF:0000107
TLR2Green Monkeycellular response to lipoteichoic acid involved_inISOTLR2 (Homo sapiens)9068941 PMID:26649771UniProtPMID:26649771
TLR2Green Monkeycellular response to lipoteichoic acid acts_upstream_of_or_withinIEAUniProtKB:O60603 and ensembl:ENSP00000494425150520179 EnsemblGO_REF:0000107
TLR2Green Monkeycellular response to peptidoglycan acts_upstream_of_or_withinISOTlr2 (Mus musculus)9068941 PMID:16949315MGIPMID:16949315
TLR2Green Monkeycellular response to triacyl bacterial lipopeptide acts_upstream_of_or_withinIEAUniProtKB:O60603 and ensembl:ENSP00000494425150520179 EnsemblGO_REF:0000107
TLR2Green Monkeycellular response to triacyl bacterial lipopeptide involved_inISOTLR2 (Homo sapiens)9068941 PMID:16880211UniProtPMID:16880211
TLR2Green Monkeycellular response to type II interferon involved_inIEAUniProtKB:O60603 and ensembl:ENSP00000494425150520179 EnsemblGO_REF:0000107
TLR2Green Monkeycentral nervous system myelin formation  ISOTlr2 (Rattus norvegicus)9068941 RGDPMID:21971760 and REF_RGD_ID:7241097
TLR2Green Monkeydefense response acts_upstream_of_or_withinISOMGI:21786759068941 PMID:12091878MGIPMID:12091878
TLR2Green Monkeydefense response to Gram-positive bacterium involved_inIEAUniProtKB:O60603 and ensembl:ENSP00000494425150520179 EnsemblGO_REF:0000107
TLR2Green Monkeydefense response to Gram-positive bacterium acts_upstream_of_or_withinISOMGI:26740369068941 PMID:15690042 and PMID:19139201MGIPMID:15690042 and PMID:19139201
TLR2Green Monkeydefense response to Gram-positive bacterium acts_upstream_of_or_withinISOMGI:21786759068941 PMID:11067888MGIPMID:11067888
TLR2Green Monkeydefense response to virus involved_inIEAUniProtKB:O60603 and ensembl:ENSP00000494425150520179 EnsemblGO_REF:0000107
TLR2Green Monkeydetection of diacyl bacterial lipopeptide acts_upstream_of_or_withinIEAUniProtKB:O60603 and ensembl:ENSP00000494425150520179 EnsemblGO_REF:0000107
TLR2Green Monkeydetection of triacyl bacterial lipopeptide acts_upstream_of_or_withinIEAUniProtKB:O60603 and ensembl:ENSP00000494425150520179 EnsemblGO_REF:0000107
TLR2Green MonkeyERK1 and ERK2 cascade acts_upstream_ofISOMGI:26740369068941 PMID:22033934MGIPMID:22033934
1 to 20 of 112 rows

Cellular Component
1 to 20 of 23 rows

  
Object Symbol
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Original Reference(s)
TLR2Green Monkeycell body  ISOTlr2 (Rattus norvegicus)9068941 RGDPMID:21971760 and REF_RGD_ID:7241097
TLR2Green Monkeycell projection  ISOTlr2 (Rattus norvegicus)9068941 RGDPMID:21971760 and REF_RGD_ID:7241097
TLR2Green Monkeycell surface  ISOTlr2 (Rattus norvegicus)9068941 RGDPMID:21765618 and REF_RGD_ID:7241098
TLR2Green Monkeycell surface located_inIEAUniProtKB:O60603 and ensembl:ENSP00000494425150520179 EnsemblGO_REF:0000107
TLR2Green Monkeycytoplasm located_inIEAUniProtKB:O60603 and ensembl:ENSP00000494425150520179 EnsemblGO_REF:0000107
TLR2Green Monkeycytoplasmic vesicle located_inIEAUniProtKB-KW:KW-0968150520179 UniProtGO_REF:0000043
TLR2Green Monkeycytosol located_inIEAUniProtKB:A0A0S2Z4S4 more ...150520179 EnsemblGO_REF:0000107
TLR2Green Monkeyexternal side of plasma membrane located_inISOTlr2 (Mus musculus)9068941 PMID:15220916MGIPMID:15220916
TLR2Green MonkeyGolgi apparatus located_inIEAUniProtKB:O60603 and ensembl:ENSP00000494425150520179 EnsemblGO_REF:0000107
TLR2Green Monkeyintracellular membrane-bounded organelle located_inIEAUniProtKB:A0A0S2Z4S4 more ...150520179 EnsemblGO_REF:0000107
TLR2Green Monkeymembrane located_inIEAUniProtKB-KW:KW-0472150520179 UniProtGO_REF:0000043
TLR2Green Monkeymembrane located_inIEAUniProtKB-SubCell:SL-0162150520179 UniProtGO_REF:0000044
TLR2Green Monkeymembrane located_inIEAInterPro:IPR017241150520179 InterProGO_REF:0000002
TLR2Green Monkeymembrane raft located_inIEAUniProtKB:O60603 and ensembl:ENSP00000494425150520179 EnsemblGO_REF:0000107
TLR2Green Monkeymembrane raft located_inIEAUniProtKB-SubCell:SL-0370150520179 UniProtGO_REF:0000044
TLR2Green Monkeynucleoplasm located_inIEAUniProtKB:A0A0S2Z4S4 more ...150520179 EnsemblGO_REF:0000107
TLR2Green Monkeyphagocytic vesicle membrane located_inIEAUniProtKB-SubCell:SL-0205150520179 UniProtGO_REF:0000044
TLR2Green Monkeyplasma membrane located_inIEAPANTHER:PTN008402304150520179 TreeGrafterGO_REF:0000118
TLR2Green Monkeyplasma membrane located_inIEAUniProtKB:A0A0S2Z4S4 more ...150520179 EnsemblGO_REF:0000107
TLR2Green Monkeyreceptor complex part_ofIEAUniProtKB:O60603 and ensembl:ENSP00000494425150520179 EnsemblGO_REF:0000107
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Molecular Function
1 to 20 of 37 rows

  
Object Symbol
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Term
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Evidence
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Reference
Notes
Source
Original Reference(s)
TLR2Green Monkeyamyloid-beta binding enablesIEAUniProtKB:O60603 and ensembl:ENSP00000494425150520179 EnsemblGO_REF:0000107
TLR2Green Monkeydiacyl lipopeptide binding enablesISOTlr2 (Mus musculus)9068941 PMID:17889651 and PMID:19931471MGIPMID:17889651 and PMID:19931471
TLR2Green Monkeyidentical protein binding enablesIEAUniProtKB:O60603 and ensembl:ENSP00000494425150520179 EnsemblGO_REF:0000107
TLR2Green Monkeylipopeptide binding  ISOTlr2 (Rattus norvegicus)9068941 RGDPMID:18353287 and REF_RGD_ID:5684896
TLR2Green Monkeylipopolysaccharide binding enablesIEAUniProtKB:O60603 and ensembl:ENSP00000494425150520179 EnsemblGO_REF:0000107
TLR2Green Monkeylipoteichoic acid binding enablesISOTlr2 (Mus musculus)9068941 PMID:19931471MGIPMID:19931471
TLR2Green Monkeypattern recognition receptor activity enablesIEAUniProtKB:O60603 and ensembl:ENSP00000494425150520179 EnsemblGO_REF:0000107
TLR2Green Monkeypeptidoglycan binding enablesIEAUniProtKB:O60603 and ensembl:ENSP00000494425150520179 EnsemblGO_REF:0000107
TLR2Green Monkeyprotein binding enablesISOUniProtKB:Q8K1L59068941 PMID:27805901UniProtPMID:27805901
TLR2Green Monkeyprotein binding enablesISOUniProtKB:O00834 and UniProtKB:Q9XZH79068941 PMID:31226171UniProtPMID:31226171
TLR2Green Monkeyprotein binding enablesISOPR:Q9EPW99068941 PMID:19931471MGIPMID:19931471
TLR2Green Monkeyprotein binding enablesISOUniProtKB:Q99JY19068941 PMID:17322885BHF-UCLPMID:17322885
TLR2Green Monkeyprotein binding enablesISOUniProtKB:P223669068941 PMID:16832055 more ...IntActPMID:16832055 more ...
TLR2Green Monkeyprotein binding enablesISOUniProtKB:P08571 more ...9068941 PMID:16880211UniProtPMID:16880211
TLR2Green Monkeyprotein binding enablesISOUniProtKB:Q9Y2C99068941 PMID:20067962IntActPMID:20067962
TLR2Green Monkeyprotein binding enablesISOUniProtKB:Q998369068941 PMID:16293622 and PMID:29990310IntActPMID:16293622 and PMID:29990310
TLR2Green Monkeyprotein binding enablesISOUniProtKB:Q9BXR59068941 PMID:15728506IntActPMID:15728506
TLR2Green Monkeyprotein binding enablesISOUniProtKB:Q15399 more ...9068941 PMID:23155421IntActPMID:23155421
TLR2Green Monkeyprotein binding enablesISOUniProtKB:P005339068941 PMID:24658140 and PMID:31980649IntActPMID:24658140 and PMID:31980649
TLR2Green Monkeyprotein binding enablesISOUniProtKB:P00533 and UniProtKB:Q998369068941 PMID:17126326IntActPMID:17126326
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RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TLR2Green MonkeyToll-like receptor signaling pathway   ISOTlr2 (Rattus norvegicus)9068941 RGDPMID:16973131 more ...
TLR2Green MonkeyToll-like receptor signaling pathway   ISOTLR2 (Homo sapiens)9068941 RGDPMID:21235323 and REF_RGD_ID:5685014
PMID:22301074   PMID:30032202  



TLR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17100,239,533 - 100,565,955 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7100,258,441 - 100,260,795 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603779,891,761 - 79,956,832 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TLR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384153,684,280 - 153,710,637 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4153,684,050 - 153,706,260 (+)EnsemblGRCh38hg38GRCh38
GRCh374154,605,432 - 154,627,412 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364154,824,891 - 154,846,693 (+)NCBINCBI36Build 36hg18NCBI36
Build 344154,966,670 - 154,984,135NCBI
Celera4151,929,928 - 151,951,730 (+)NCBICelera
Cytogenetic Map4q31.3NCBI
HuRef4150,336,457 - 150,358,268 (+)NCBIHuRef
CHM1_14154,583,811 - 154,605,614 (+)NCBICHM1_1
T2T-CHM13v2.04157,008,777 - 157,030,716 (+)NCBIT2T-CHM13v2.0
Tlr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39383,743,579 - 83,749,045 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl383,743,579 - 83,749,074 (-)EnsemblGRCm39 Ensembl
GRCm38383,836,272 - 83,841,824 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl383,836,272 - 83,841,767 (-)EnsemblGRCm38mm10GRCm38
MGSCv37383,640,194 - 83,645,530 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36383,922,199 - 83,927,694 (-)NCBIMGSCv36mm8
Celera383,852,064 - 83,857,400 (-)NCBICelera
Cytogenetic Map3E3NCBI
cM Map337.4NCBI
Tlr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82171,499,189 - 171,504,831 (-)NCBIGRCr8
mRatBN7.22169,200,620 - 169,206,819 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2169,197,419 - 169,206,630 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2176,379,970 - 176,385,353 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02174,399,903 - 174,405,286 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02169,001,363 - 169,006,752 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02182,840,171 - 182,846,061 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2182,840,727 - 182,846,061 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02202,252,701 - 202,258,962 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42175,607,990 - 175,613,992 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12175,558,096 - 175,564,098 (-)NCBI
Celera2163,202,040 - 163,207,399 (-)NCBICelera
Cytogenetic Map2q34NCBI
Tlr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554718,014,910 - 8,017,258 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554718,011,710 - 8,019,063 (+)NCBIChiLan1.0ChiLan1.0
TLR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23151,528,318 - 151,594,177 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14151,924,943 - 151,949,250 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04146,024,653 - 146,091,388 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14157,848,058 - 157,870,324 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4157,866,977 - 157,869,331 (+)Ensemblpanpan1.1panPan2
TLR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11551,454,557 - 51,465,429 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1551,454,695 - 51,465,241 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1551,808,717 - 51,811,083 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01552,140,775 - 52,151,566 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11551,404,786 - 51,407,152 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01551,510,608 - 51,512,974 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01551,821,784 - 51,824,151 (+)NCBIUU_Cfam_GSD_1.0
Tlr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530139,016,995 - 39,024,812 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936576527,434 - 529,788 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936576522,234 - 531,660 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TLR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl875,411,993 - 75,428,330 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1875,416,257 - 75,428,370 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2879,823,867 - 79,834,881 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Tlr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248584,979,485 - 4,981,833 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248584,931,820 - 4,984,175 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in TLR2
7517 total Variants



ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20



Ensembl Acc Id: ENSCSAT00000018150   ⟹   ENSCSAP00000017617
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl7100,258,441 - 100,260,795 (+)Ensembl
RefSeq Acc Id: XM_008000045   ⟹   XP_007998236
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.17100,239,533 - 100,260,988 (+)NCBI
Vero_WHO_p1.0NW_02366603779,892,245 - 79,916,971 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008000046   ⟹   XP_007998237
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.17100,239,545 - 100,260,988 (+)NCBI
Vero_WHO_p1.0NW_02366603779,892,312 - 79,913,378 (+)NCBI
Sequence:
RefSeq Acc Id: XR_005238665
Type: NON-CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603779,891,761 - 79,956,832 (+)NCBI
RefSeq Acc Id: XR_005238667
Type: NON-CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603779,892,039 - 79,931,247 (+)NCBI
RefSeq Acc Id: XR_005238668
Type: NON-CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603779,891,761 - 79,929,186 (+)NCBI
Protein RefSeqs XP_007998236 (Get FASTA)   NCBI Sequence Viewer  
  XP_007998237 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000017617.1
RefSeq Acc Id: XP_007998236   ⟸   XM_008000045
- UniProtKB: A0A0D9S9S8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007998237   ⟸   XM_008000046
- UniProtKB: A0A0D9S9S8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000017617   ⟸   ENSCSAT00000018150



1 to 32 of 32 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCSAG00000000385 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000018150.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.10140 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro Cys-rich_flank_reg_C UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  TIR_dom UniProtKB/TrEMBL
  Toll-like_receptor UniProtKB/TrEMBL
  Toll_tir_struct_dom_sf UniProtKB/TrEMBL
KEGG Report csab:103236415 UniProtKB/TrEMBL
NCBI Gene LOC103236415 ENTREZGENE
PANTHER PTHR24365 UniProtKB/TrEMBL
  PTHR24365:SF17 UniProtKB/TrEMBL
Pfam LRR_1 UniProtKB/TrEMBL
  LRR_8 UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
  TIR UniProtKB/TrEMBL
PIRSF Toll-like_receptor UniProtKB/TrEMBL
PRINTS INTRLKN1R1F UniProtKB/TrEMBL
  LEURICHRPT UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
  TIR UniProtKB/TrEMBL
SMART LRR_BAC UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
  TIR UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
  RNI-like UniProtKB/TrEMBL
  SSF52200 UniProtKB/TrEMBL
UniProt A0A0D9S9S8 ENTREZGENE, UniProtKB/TrEMBL
1 to 32 of 32 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-08 TLR2  toll like receptor 2  LOC103236415  toll-like receptor 2  Symbol and/or name change 5135510 APPROVED