TLR2 (toll like receptor 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: TLR2 (toll like receptor 2) Sus scrofa
Analyze
Symbol: TLR2
Name: toll like receptor 2
RGD ID: 14224907
Description: ENCODES a protein that exhibits diacyl lipopeptide binding (ortholog); lipopeptide binding (ortholog); lipoteichoic acid binding (ortholog); INVOLVED IN cell surface pattern recognition receptor signaling pathway (ortholog); cellular response to bacterial lipopeptide (ortholog); cellular response to diacyl bacterial lipopeptide (ortholog); PARTICIPATES IN Toll-like receptor signaling pathway; ASSOCIATED WITH abdominal obesity-metabolic syndrome 1 (ortholog); acne (ortholog); acute kidney failure (ortholog); FOUND IN cell body (ortholog); cell projection (ortholog); cell surface (ortholog); INTERACTS WITH bis(2-chloroethyl) sulfide; dibromine; zearalenone
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: toll-like receptor 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl875,411,993 - 75,428,330 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1875,416,257 - 75,428,370 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2879,823,867 - 79,834,881 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
abdominal obesity-metabolic syndrome 1  (ISO)
acne  (ISO)
acute kidney failure  (ISO)
acute necrotizing pancreatitis  (ISO)
Acute Tubulointerstitial Nephritis  (ISO)
allergic conjunctivitis  (ISO)
allergic rhinitis  (ISO)
alveolar echinococcosis  (ISO)
anogenital venereal wart  (ISO)
anterior uveitis  (ISO)
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis  (ISO)
aspergillosis  (ISO)
asthma  (ISO)
atherosclerosis  (ISO)
atopic dermatitis  (ISO)
atrial fibrillation  (ISO)
Bacterial Eye Infections  (ISO)
Bacterial Keratitis  (ISO)
bacterial pneumonia  (ISO)
Behcet's disease  (ISO)
Brain Abscess  (ISO)
Brain Hypoxia-Ischemia  (ISO)
Brain Injuries  (ISO)
breast cancer  (ISO)
cardiomyopathy  (ISO)
Cardiotoxicity  (ISO)
carotid artery thrombosis  (ISO)
carotid stenosis  (ISO)
cholangitis  (ISO)
cholestasis  (ISO)
cholesteatoma  (ISO)
cholesteatoma of middle ear  (ISO)
Choroidal Neovascularization  (ISO)
Chronic Hepatitis B  (ISO)
Chronic Pain  (ISO)
Chronic Periodontitis  (ISO)
clonorchiasis  (ISO)
colorectal cancer  (ISO)
Colorectal Neoplasms  (ISO)
congestive heart failure  (ISO)
Cough  (ISO)
cutaneous leishmaniasis  (ISO)
cystic echinococcosis  (ISO)
dermatomyositis  (ISO)
Diabetic Nephropathies  (ISO)
diffuse scleroderma  (ISO)
Drug-Related Side Effects and Adverse Reactions  (ISO)
dry eye syndrome  (ISO)
Dyslipidemias  (ISO)
end stage renal disease  (ISO)
endophthalmitis  (ISO)
Endotoxemia  (ISO)
Eosinophilia  (ISO)
eumycotic mycetoma  (ISO)
Experimental Arthritis  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Autoimmune Neuritis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
eye disease  (ISO)
Fever  (ISO)
Fungal Eye Infections  (ISO)
gastroesophageal reflux disease  (ISO)
glomerulonephritis  (ISO)
Gram-Positive Bacterial Infections  (ISO)
Hearing Loss  (ISO)
hepatitis B  (ISO)
hepatocellular carcinoma  (ISO)
Herpes Simplex Encephalitis  (ISO)
herpes simplex virus keratitis  (ISO)
Human Influenza  (ISO)
Hyperalgesia  (ISO)
ileitis  (ISO)
Inflammation  (ISO)
invasive aspergillosis  (ISO)
keratitis  (ISO)
keratoconjunctivitis  (ISO)
kidney failure  (ISO)
Kidney Reperfusion Injury  (ISO)
Kuhnt-Junius degeneration  (ISO)
leprosy  (ISO)
leptospirosis  (ISO)
liver cirrhosis  (ISO)
Liver Reperfusion Injury  (ISO)
lung disease  (ISO)
mastoiditis  (ISO)
membranoproliferative glomerulonephritis  (ISO)
Meningitis, Escherichia Coli  (ISO)
meningococcal meningitis  (ISO)
mite infestation  (ISO)
molluscum contagiosum  (ISO)
myelodysplastic syndrome  (ISO)
Myocardial Reperfusion Injury  (ISO)
Nasal Polyps  (ISO)
non-alcoholic steatohepatitis  (ISO)
obesity  (ISO)
obstructive jaundice  (ISO)
Oral Lichen Planus  (ISO)
otitis media  (ISO)
Otitis Media with Effusion  (ISO)
Pain  (ISO)
pancreatitis  (ISO)
perinatal necrotizing enterocolitis  (ISO)
Plaque, Atherosclerotic  (ISO)
Pneumococcal Meningitis  (ISO)
Pneumococcal Pneumonia  (ISO)
pneumocystosis  (ISO)
pneumonia  (ISO)
prostate cancer  (ISO)
Pseudomonas Aeruginosa Keratitis  (ISO)
psoriasis  (ISO)
pulmonary emphysema  (ISO)
pulmonary fibrosis  (ISO)
pulmonary sarcoidosis  (ISO)
pulmonary tuberculosis  (ISO)
renal fibrosis  (ISO)
Reperfusion Injury  (ISO)
respiratory syncytial virus infectious disease  (ISO)
rheumatoid arthritis  (ISO)
rhinitis  (ISO)
Rhinosinusitis  (ISO)
sciatic neuropathy  (ISO)
seborrheic dermatitis  (ISO)
Sepsis  (ISO)
severe acute respiratory syndrome  (ISO)
sinusitis  (ISO)
skin papilloma  (ISO)
Staphylococcal Infections  (ISO)
Streptococcal Infections  (ISO)
suppurative otitis media  (ISO)
Transplant Rejection  (ISO)
tuberculosis  (ISO)
type 1 diabetes mellitus  (ISO)
typhoid fever  (ISO)
urinary bladder cancer  (ISO)
urinary tract infection  (ISO)
visceral leishmaniasis  (ISO)
vitiligo  (ISO)
Wallerian Degeneration  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cell activation  (IEA)
cell surface pattern recognition receptor signaling pathway  (ISO)
cellular response to bacterial lipopeptide  (ISO)
cellular response to diacyl bacterial lipopeptide  (IEA,ISO)
cellular response to lipoteichoic acid  (IEA,ISO)
cellular response to peptidoglycan  (ISO)
cellular response to triacyl bacterial lipopeptide  (IEA,ISO)
cellular response to type II interferon  (IEA)
central nervous system myelin formation  (ISO)
defense response  (ISO)
defense response to Gram-positive bacterium  (IEA,ISO)
defense response to virus  (IEA)
detection of diacyl bacterial lipopeptide  (IEA,ISO)
detection of triacyl bacterial lipopeptide  (IEA,ISO)
ERK1 and ERK2 cascade  (ISO)
I-kappaB phosphorylation  (IEA)
immune response  (IEA)
immune system process  (IEA)
inflammatory response  (IBA,IEA,ISO)
innate immune response  (IEA)
learning  (ISO)
leukocyte migration  (ISO)
leukotriene metabolic process  (ISO)
microglia development  (ISO)
microglial cell activation  (ISO)
MyD88-dependent toll-like receptor signaling pathway  (IEA,ISO)
negative regulation of actin filament polymerization  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of interleukin-12 production  (ISO)
negative regulation of interleukin-17 production  (ISO)
negative regulation of phagocytosis  (ISO)
negative regulation of synapse assembly  (ISO)
neutrophil migration  (ISO)
NIK/NF-kappaB signaling  (ISO)
nitric oxide biosynthetic process  (ISO)
nitric oxide metabolic process  (ISO)
positive regulation of cellular response to macrophage colony-stimulating factor stimulus  (IEA)
positive regulation of chemokine production  (IEA,ISO)
positive regulation of cytokine production  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of gene expression  (IEA)
positive regulation of inflammatory response  (IEA)
positive regulation of interferon-beta production  (ISO)
positive regulation of interleukin-1 beta production  (ISO)
positive regulation of interleukin-10 production  (ISO)
positive regulation of interleukin-12 production  (ISO)
positive regulation of interleukin-18 production  (ISO)
positive regulation of interleukin-6 production  (IEA,ISO)
positive regulation of interleukin-8 production  (IEA)
positive regulation of leukocyte migration  (ISO)
positive regulation of macrophage cytokine production  (ISO)
positive regulation of matrix metallopeptidase secretion  (IEA)
positive regulation of neutrophil migration  (ISO)
positive regulation of NF-kappaB transcription factor activity  (IEA,ISO)
positive regulation of NIK/NF-kappaB signaling  (IEA,ISO)
positive regulation of nitric oxide biosynthetic process  (ISO)
positive regulation of nitric-oxide synthase biosynthetic process  (ISO)
positive regulation of oligodendrocyte differentiation  (ISO)
positive regulation of toll-like receptor signaling pathway  (IEA)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of tumor necrosis factor production  (ISO)
positive regulation of Wnt signaling pathway  (IEA)
positive regulation of xenophagy  (ISO)
regulation of cytokine production  (IEA)
regulation of dendritic cell cytokine production  (ISO)
response to bacterial lipoprotein  (ISO)
response to bacterium  (ISO)
response to fatty acid  (ISO)
response to hypoxia  (ISO)
response to insulin  (ISO)
response to lipopolysaccharide  (ISO)
response to molecule of bacterial origin  (IEA)
response to molecule of fungal origin  (ISO)
response to peptidoglycan  (ISO)
response to progesterone  (ISO)
response to toxic substance  (ISO)
signal transduction  (IEA)
toll-like receptor 2 signaling pathway  (IEA)
toll-like receptor signaling pathway  (IBA,IEA,ISO)
toll-like receptor TLR6:TLR2 signaling pathway  (IEA)
xenophagy  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14585198   PMID:15796917   PMID:15907450   PMID:16604477   PMID:18096121   PMID:18562167   PMID:19953243   PMID:20099714   PMID:23974322   PMID:24733511   PMID:24995380   PMID:25380861  
PMID:25466614   PMID:25814121   PMID:26581603   PMID:26857454   PMID:29125848   PMID:29555549   PMID:31127671   PMID:31174697  


Genomics

Comparative Map Data
TLR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl875,411,993 - 75,428,330 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1875,416,257 - 75,428,370 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2879,823,867 - 79,834,881 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TLR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384153,684,280 - 153,710,637 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl4153,684,070 - 153,706,260 (+)EnsemblGRCh38hg38GRCh38
GRCh374154,605,432 - 154,627,412 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364154,824,891 - 154,846,693 (+)NCBINCBI36Build 36hg18NCBI36
Build 344154,966,670 - 154,984,135NCBI
Celera4151,929,928 - 151,951,730 (+)NCBICelera
Cytogenetic Map4q31.3NCBI
HuRef4150,336,457 - 150,358,268 (+)NCBIHuRef
CHM1_14154,583,811 - 154,605,614 (+)NCBICHM1_1
T2T-CHM13v2.04157,008,777 - 157,030,716 (+)NCBIT2T-CHM13v2.0
Tlr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39383,743,579 - 83,749,045 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl383,743,579 - 83,749,074 (-)EnsemblGRCm39 Ensembl
GRCm38383,836,272 - 83,841,824 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl383,836,272 - 83,841,767 (-)EnsemblGRCm38mm10GRCm38
MGSCv37383,640,194 - 83,645,530 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36383,922,199 - 83,927,694 (-)NCBIMGSCv36mm8
Celera383,852,064 - 83,857,400 (-)NCBICelera
Cytogenetic Map3E3NCBI
Tlr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22169,200,620 - 169,206,819 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2169,197,419 - 169,206,630 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2176,379,970 - 176,385,353 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.02174,399,903 - 174,405,286 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.02169,001,363 - 169,006,752 (-)NCBIRnor_WKY
Rnor_6.02182,840,171 - 182,846,061 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2182,840,727 - 182,846,061 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02202,252,701 - 202,258,962 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42175,607,990 - 175,613,992 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12175,558,096 - 175,564,098 (-)NCBI
Celera2163,202,040 - 163,207,399 (-)NCBICelera
Cytogenetic Map2q34NCBI
Tlr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554718,014,910 - 8,017,258 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554718,011,710 - 8,019,063 (+)NCBIChiLan1.0ChiLan1.0
TLR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.14157,848,058 - 157,870,324 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4157,866,977 - 157,869,331 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v04146,024,653 - 146,091,388 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
TLR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11551,454,557 - 51,465,429 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1551,454,695 - 51,465,241 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1551,808,717 - 51,811,083 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01552,140,775 - 52,151,566 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11551,404,786 - 51,407,152 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01551,510,608 - 51,512,974 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01551,821,784 - 51,824,151 (+)NCBIUU_Cfam_GSD_1.0
Tlr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530139,016,995 - 39,024,812 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936576522,234 - 531,660 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TLR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17100,239,533 - 100,565,955 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7100,258,441 - 100,260,795 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603779,891,761 - 79,956,832 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tlr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248584,979,485 - 4,981,833 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248584,931,820 - 4,984,175 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 4 2 2
Low 6 4 3 3 2 22 2 3 1
Below cutoff 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_213761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005653576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005653577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005653578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005653579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB066104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB072190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB085935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB208696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEMK02000067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ583829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK230635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK231862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK240429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK391277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK398028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY289531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY373816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY392087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY392088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU180626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU527013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FP086612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GFLN01047930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ304753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU138028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF460452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSSCT00000009859   ⟹   ENSSSCP00000009606
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl875,417,875 - 75,427,910 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000033729   ⟹   ENSSSCP00000030722
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl875,417,877 - 75,428,330 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000054433   ⟹   ENSSSCP00000049323
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl875,416,021 - 75,422,029 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000064428   ⟹   ENSSSCP00000045396
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl875,417,877 - 75,427,666 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000079173   ⟹   ENSSSCP00000072694
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl875,417,861 - 75,446,850 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000082620   ⟹   ENSSSCP00000067954
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl875,411,993 - 75,427,028 (-)Ensembl
RefSeq Acc Id: NM_213761   ⟹   NP_998926
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1875,417,864 - 75,427,910 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005653576   ⟹   XP_005653633
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1875,416,257 - 75,427,094 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005653577   ⟹   XP_005653634
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1875,417,794 - 75,428,370 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005653578   ⟹   XP_005653635
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1875,417,794 - 75,427,780 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005653579   ⟹   XP_005653636
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1875,417,794 - 75,427,904 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_005653633   ⟸   XM_005653576
- Peptide Label: isoform X1
- UniProtKB: Q59HI8 (UniProtKB/TrEMBL),   A0A287AZK0 (UniProtKB/TrEMBL),   A0A8D0TKU7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005653634   ⟸   XM_005653577
- Peptide Label: isoform X1
- UniProtKB: Q59HI8 (UniProtKB/TrEMBL),   A0A287AZK0 (UniProtKB/TrEMBL),   A0A8D0TKU7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005653636   ⟸   XM_005653579
- Peptide Label: isoform X1
- UniProtKB: Q59HI8 (UniProtKB/TrEMBL),   A0A287AZK0 (UniProtKB/TrEMBL),   A0A8D0TKU7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005653635   ⟸   XM_005653578
- Peptide Label: isoform X1
- UniProtKB: Q59HI8 (UniProtKB/TrEMBL),   A0A287AZK0 (UniProtKB/TrEMBL),   A0A8D0TKU7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_998926   ⟸   NM_213761
- Peptide Label: precursor
- UniProtKB: Q6TN21 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000049323   ⟸   ENSSSCT00000054433
RefSeq Acc Id: ENSSSCP00000045396   ⟸   ENSSSCT00000064428
RefSeq Acc Id: ENSSSCP00000009606   ⟸   ENSSSCT00000009859
RefSeq Acc Id: ENSSSCP00000072694   ⟸   ENSSSCT00000079173
RefSeq Acc Id: ENSSSCP00000067954   ⟸   ENSSSCT00000082620
RefSeq Acc Id: ENSSSCP00000030722   ⟸   ENSSSCT00000033729
Protein Domains
TIR


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000009002 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005024396 UniProtKB/TrEMBL
  ENSSSCG00015075794 UniProtKB/TrEMBL
  ENSSSCG00025074587 UniProtKB/TrEMBL
  ENSSSCG00030014009 UniProtKB/TrEMBL
  ENSSSCG00035018537 UniProtKB/TrEMBL
  ENSSSCG00040074832 UniProtKB/TrEMBL
  ENSSSCG00045004792 UniProtKB/TrEMBL
  ENSSSCG00050005791 UniProtKB/TrEMBL
  ENSSSCG00055010909 UniProtKB/TrEMBL
  ENSSSCG00060040452 UniProtKB/TrEMBL
  ENSSSCG00070003547 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000009606 ENTREZGENE
  ENSSSCP00000009606.1 UniProtKB/TrEMBL
  ENSSSCP00000030722 ENTREZGENE
  ENSSSCP00000030722.1 UniProtKB/TrEMBL
  ENSSSCP00000045396 ENTREZGENE
  ENSSSCP00000045396.1 UniProtKB/TrEMBL
  ENSSSCP00000049323.2 UniProtKB/TrEMBL
  ENSSSCP00000067954 ENTREZGENE
  ENSSSCP00000067954.1 UniProtKB/TrEMBL
  ENSSSCP00000072694.1 UniProtKB/TrEMBL
  ENSSSCP00005023731.1 UniProtKB/TrEMBL
  ENSSSCP00005023750.1 UniProtKB/TrEMBL
  ENSSSCP00005023758.1 UniProtKB/TrEMBL
  ENSSSCP00005023769.1 UniProtKB/TrEMBL
  ENSSSCP00015042335.1 UniProtKB/TrEMBL
  ENSSSCP00015042470.1 UniProtKB/TrEMBL
  ENSSSCP00015042524.1 UniProtKB/TrEMBL
  ENSSSCP00015042676.1 UniProtKB/TrEMBL
  ENSSSCP00015042693.1 UniProtKB/TrEMBL
  ENSSSCP00015042707.1 UniProtKB/TrEMBL
  ENSSSCP00015042726.1 UniProtKB/TrEMBL
  ENSSSCP00025045559.1 UniProtKB/TrEMBL
  ENSSSCP00025045575.1 UniProtKB/TrEMBL
  ENSSSCP00025045621.1 UniProtKB/TrEMBL
  ENSSSCP00025045630.1 UniProtKB/TrEMBL
  ENSSSCP00025045646.1 UniProtKB/TrEMBL
  ENSSSCP00025045674.1 UniProtKB/TrEMBL
  ENSSSCP00030008592.1 UniProtKB/TrEMBL
  ENSSSCP00030008594.1 UniProtKB/TrEMBL
  ENSSSCP00030008602.1 UniProtKB/TrEMBL
  ENSSSCP00030008603.1 UniProtKB/TrEMBL
  ENSSSCP00030008605.1 UniProtKB/TrEMBL
  ENSSSCP00030008612.1 UniProtKB/TrEMBL
  ENSSSCP00035008951.1 UniProtKB/TrEMBL
  ENSSSCP00035008953.1 UniProtKB/TrEMBL
  ENSSSCP00035008956.1 UniProtKB/TrEMBL
  ENSSSCP00035008957.1 UniProtKB/TrEMBL
  ENSSSCP00035008959.1 UniProtKB/TrEMBL
  ENSSSCP00035008966.1 UniProtKB/TrEMBL
  ENSSSCP00040046975.1 UniProtKB/TrEMBL
  ENSSSCP00040046982.1 UniProtKB/TrEMBL
  ENSSSCP00040047001.1 UniProtKB/TrEMBL
  ENSSSCP00040047004.1 UniProtKB/TrEMBL
  ENSSSCP00040047006.1 UniProtKB/TrEMBL
  ENSSSCP00040047018.1 UniProtKB/TrEMBL
  ENSSSCP00045005316.1 UniProtKB/TrEMBL
  ENSSSCP00045005318.1 UniProtKB/TrEMBL
  ENSSSCP00045005322.1 UniProtKB/TrEMBL
  ENSSSCP00045005323.1 UniProtKB/TrEMBL
  ENSSSCP00045005326.1 UniProtKB/TrEMBL
  ENSSSCP00045005328.1 UniProtKB/TrEMBL
  ENSSSCP00050003335.1 UniProtKB/TrEMBL
  ENSSSCP00050003340.1 UniProtKB/TrEMBL
  ENSSSCP00050003355.1 UniProtKB/TrEMBL
  ENSSSCP00050003365.1 UniProtKB/TrEMBL
  ENSSSCP00050003368.1 UniProtKB/TrEMBL
  ENSSSCP00050003371.1 UniProtKB/TrEMBL
  ENSSSCP00050003376.1 UniProtKB/TrEMBL
  ENSSSCP00055016969.1 UniProtKB/TrEMBL
  ENSSSCP00055016982.1 UniProtKB/TrEMBL
  ENSSSCP00055017005.1 UniProtKB/TrEMBL
  ENSSSCP00055017010.1 UniProtKB/TrEMBL
  ENSSSCP00055017022.1 UniProtKB/TrEMBL
  ENSSSCP00055017037.1 UniProtKB/TrEMBL
  ENSSSCP00060023366.1 UniProtKB/TrEMBL
  ENSSSCP00060023372.1 UniProtKB/TrEMBL
  ENSSSCP00060023394.1 UniProtKB/TrEMBL
  ENSSSCP00060023428.1 UniProtKB/TrEMBL
  ENSSSCP00060023433.1 UniProtKB/TrEMBL
  ENSSSCP00060023438.1 UniProtKB/TrEMBL
  ENSSSCP00060023443.1 UniProtKB/TrEMBL
  ENSSSCP00070005434.1 UniProtKB/TrEMBL
  ENSSSCP00070005452.1 UniProtKB/TrEMBL
  ENSSSCP00070005457.1 UniProtKB/TrEMBL
  ENSSSCP00070005470.1 UniProtKB/TrEMBL
  ENSSSCP00070005481.1 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000009859 ENTREZGENE
  ENSSSCT00000009859.4 UniProtKB/TrEMBL
  ENSSSCT00000033729 ENTREZGENE
  ENSSSCT00000033729.3 UniProtKB/TrEMBL
  ENSSSCT00000054433.2 UniProtKB/TrEMBL
  ENSSSCT00000064428 ENTREZGENE
  ENSSSCT00000064428.2 UniProtKB/TrEMBL
  ENSSSCT00000079173.1 UniProtKB/TrEMBL
  ENSSSCT00000082620 ENTREZGENE
  ENSSSCT00000082620.1 UniProtKB/TrEMBL
  ENSSSCT00005038654.1 UniProtKB/TrEMBL
  ENSSSCT00005038679.1 UniProtKB/TrEMBL
  ENSSSCT00005038687.1 UniProtKB/TrEMBL
  ENSSSCT00005038704.1 UniProtKB/TrEMBL
  ENSSSCT00015102130.1 UniProtKB/TrEMBL
  ENSSSCT00015102343.1 UniProtKB/TrEMBL
  ENSSSCT00015102429.1 UniProtKB/TrEMBL
  ENSSSCT00015102678.1 UniProtKB/TrEMBL
  ENSSSCT00015102715.1 UniProtKB/TrEMBL
  ENSSSCT00015102742.1 UniProtKB/TrEMBL
  ENSSSCT00015102780.1 UniProtKB/TrEMBL
  ENSSSCT00025102868.1 UniProtKB/TrEMBL
  ENSSSCT00025102910.1 UniProtKB/TrEMBL
  ENSSSCT00025103003.1 UniProtKB/TrEMBL
  ENSSSCT00025103021.1 UniProtKB/TrEMBL
  ENSSSCT00025103047.1 UniProtKB/TrEMBL
  ENSSSCT00025103100.1 UniProtKB/TrEMBL
  ENSSSCT00030019285.1 UniProtKB/TrEMBL
  ENSSSCT00030019289.1 UniProtKB/TrEMBL
  ENSSSCT00030019312.1 UniProtKB/TrEMBL
  ENSSSCT00030019313.1 UniProtKB/TrEMBL
  ENSSSCT00030019320.1 UniProtKB/TrEMBL
  ENSSSCT00030019336.1 UniProtKB/TrEMBL
  ENSSSCT00035023943.1 UniProtKB/TrEMBL
  ENSSSCT00035023945.1 UniProtKB/TrEMBL
  ENSSSCT00035023960.1 UniProtKB/TrEMBL
  ENSSSCT00035023962.1 UniProtKB/TrEMBL
  ENSSSCT00035023965.1 UniProtKB/TrEMBL
  ENSSSCT00035023981.1 UniProtKB/TrEMBL
  ENSSSCT00040103563.1 UniProtKB/TrEMBL
  ENSSSCT00040103570.1 UniProtKB/TrEMBL
  ENSSSCT00040103593.1 UniProtKB/TrEMBL
  ENSSSCT00040103596.1 UniProtKB/TrEMBL
  ENSSSCT00040103602.1 UniProtKB/TrEMBL
  ENSSSCT00040103614.1 UniProtKB/TrEMBL
  ENSSSCT00045007893.1 UniProtKB/TrEMBL
  ENSSSCT00045007895.1 UniProtKB/TrEMBL
  ENSSSCT00045007902.1 UniProtKB/TrEMBL
  ENSSSCT00045007903.1 UniProtKB/TrEMBL
  ENSSSCT00045007907.1 UniProtKB/TrEMBL
  ENSSSCT00045007910.1 UniProtKB/TrEMBL
  ENSSSCT00050007873.1 UniProtKB/TrEMBL
  ENSSSCT00050007886.1 UniProtKB/TrEMBL
  ENSSSCT00050007914.1 UniProtKB/TrEMBL
  ENSSSCT00050007938.1 UniProtKB/TrEMBL
  ENSSSCT00050007942.1 UniProtKB/TrEMBL
  ENSSSCT00050007945.1 UniProtKB/TrEMBL
  ENSSSCT00050007951.1 UniProtKB/TrEMBL
  ENSSSCT00055021420.1 UniProtKB/TrEMBL
  ENSSSCT00055021434.1 UniProtKB/TrEMBL
  ENSSSCT00055021464.1 UniProtKB/TrEMBL
  ENSSSCT00055021471.1 UniProtKB/TrEMBL
  ENSSSCT00055021485.1 UniProtKB/TrEMBL
  ENSSSCT00055021504.1 UniProtKB/TrEMBL
  ENSSSCT00060054784.1 UniProtKB/TrEMBL
  ENSSSCT00060054797.1 UniProtKB/TrEMBL
  ENSSSCT00060054838.1 UniProtKB/TrEMBL
  ENSSSCT00060054896.1 UniProtKB/TrEMBL
  ENSSSCT00060054903.1 UniProtKB/TrEMBL
  ENSSSCT00060054910.1 UniProtKB/TrEMBL
  ENSSSCT00060054919.1 UniProtKB/TrEMBL
  ENSSSCT00070006664.1 UniProtKB/TrEMBL
  ENSSSCT00070006686.1 UniProtKB/TrEMBL
  ENSSSCT00070006691.1 UniProtKB/TrEMBL
  ENSSSCT00070006706.1 UniProtKB/TrEMBL
  ENSSSCT00070006719.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.10140 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro Cys-rich_flank_reg_C UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  SQR/QFR_C/D UniProtKB/TrEMBL
  TIR_dom UniProtKB/TrEMBL
  TLR2 UniProtKB/TrEMBL
  Toll-like_receptor UniProtKB/TrEMBL
  Toll_tir_struct_dom_sf UniProtKB/TrEMBL
KEGG Report ssc:396623 UniProtKB/TrEMBL
NCBI Gene TLR2 ENTREZGENE
PANTHER PTHR24365 UniProtKB/TrEMBL
  PTHR24365:SF17 UniProtKB/TrEMBL
Pfam LRR_8 UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
  TIR UniProtKB/TrEMBL
PIRSF Toll-like_receptor UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
  TIR UniProtKB/TrEMBL
SMART LRR_TYP UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
  TIR UniProtKB/TrEMBL
Superfamily-SCOP SSF52200 UniProtKB/TrEMBL
  SSF81343 UniProtKB/TrEMBL
UniProt A0A287AZK0 ENTREZGENE
  A0A4X1SRY4_PIG UniProtKB/TrEMBL
  A0A4X1SSU1_PIG UniProtKB/TrEMBL
  A0A8D0Q205_PIG UniProtKB/TrEMBL
  A0A8D0TKU7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0UCT5_PIG UniProtKB/TrEMBL
  A0A8D1QFI9_PIG UniProtKB/TrEMBL
  D3JEM3_PIG UniProtKB/TrEMBL
  Q59HI8 ENTREZGENE, UniProtKB/TrEMBL
  Q5DX20_PIG UniProtKB/TrEMBL
  Q6TN21 ENTREZGENE, UniProtKB/TrEMBL
  Q70EK5_PIG UniProtKB/TrEMBL
  Q7YSE2_PIG UniProtKB/TrEMBL
UniProt Secondary A0A287AZK0 UniProtKB/TrEMBL
VGNC ID VGNC:94024 ENTREZGENE