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Gene: Sting1 (stimulator of interferon response cGAMP interactor 1) Mus musculus
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Symbol: Sting1
Name: stimulator of interferon response cGAMP interactor 1
Description: Exhibits cyclic-GMP-AMP binding activity; cyclic-di-GMP binding activity; and ubiquitin protein ligase binding activity. Involved in several processes, including defense response to other organism; macroautophagy; and positive regulation of gene expression. Localizes to several cellular components, including autophagosome; perinuclear region of cytoplasm; and peroxisome. Human ortholog(s) of this gene implicated in STING-associated vasculopathy with onset in infancy. Orthologous to human STING1 (stimulator of interferon response cGAMP interactor 1); PARTICIPATES IN Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway; INTERACTS WITH 4,4'-sulfonyldiphenol; 4-hydroxyphenyl retinamide; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610307O08Rik; endoplasmic reticulum interferon stimulator; ERIS; mediator of IRF3 activation; Mita; mitochondrial mediator of IRF3 activation; MMITA; MPYS; mSTING; stimulator of interferon genes protein; STING; STING-beta; Tmem173; transmembrane protein 173
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1835,733,679 - 35,740,554 (-)EnsemblGRCm38mm10GRCm38
GRCm381835,733,678 - 35,740,554 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371835,893,332 - 35,900,208 (-)NCBIGRCm37mm9NCBIm37
MGSCv361835,859,652 - 35,866,528 (-)NCBImm8
Celera1836,189,779 - 36,196,655 (-)NCBICelera
Cytogenetic Map18B2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Sting1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1615847
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.