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Gene: Sting1 (stimulator of interferon response cGAMP interactor 1) Mus musculus
Symbol: Sting1
Name: stimulator of interferon response cGAMP interactor 1
Description: Exhibits cyclic-GMP-AMP binding activity; cyclic-di-GMP binding activity; and ubiquitin protein ligase binding activity. Involved in several processes, including defense response to other organism; macroautophagy; and positive regulation of gene expression. Localizes to several cellular components, including autophagosome; perinuclear region of cytoplasm; and peroxisome. Human ortholog(s) of this gene implicated in STING-associated vasculopathy with onset in infancy. Orthologous to human STING1 (stimulator of interferon response cGAMP interactor 1); PARTICIPATES IN Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway; INTERACTS WITH 4,4'-sulfonyldiphenol; 4-hydroxyphenyl retinamide; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610307O08Rik; endoplasmic reticulum interferon stimulator; ERIS; mediator of IRF3 activation; Mita; mitochondrial mediator of IRF3 activation; MMITA; MPYS; mSTING; stimulator of interferon genes protein; STING; STING-beta; Tmem173; transmembrane protein 173
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1835,733,679 - 35,740,554 (-)EnsemblGRCm38mm10GRCm38
GRCm381835,733,678 - 35,740,554 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371835,893,332 - 35,900,208 (-)NCBIGRCm37mm9NCBIm37
MGSCv361835,859,652 - 35,866,528 (-)NCBImm8
Celera1836,189,779 - 36,196,655 (-)NCBICelera
Cytogenetic Map18B2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Sting1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1615847
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.