CD274 (CD274 molecule) - Rat Genome Database

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Gene: CD274 (CD274 molecule) Pan paniscus
Analyze
Symbol: CD274
Name: CD274 molecule
RGD ID: 11982629
Description: INVOLVED IN cell surface receptor signaling pathway (ortholog); immune response (ortholog); negative regulation of activated T cell proliferation (ortholog); ASSOCIATED WITH acute myocarditis (ortholog); adult T-cell leukemia (ortholog); allergic disease (ortholog); FOUND IN actin cytoskeleton (ortholog); cell surface (ortholog); early endosome membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: programmed cell death 1 ligand 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.195,454,391 - 5,474,452 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl95,454,391 - 5,474,402 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v095,269,270 - 5,289,629 (+)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute myocarditis  (ISO)
adult T-cell leukemia  (ISO)
allergic disease  (ISO)
alveolar echinococcosis  (ISO)
anti-basement membrane glomerulonephritis  (ISO)
asthma  (ISO)
autoimmune hepatitis  (ISO)
cervix uteri carcinoma in situ  (ISO)
Chlamydia pneumonia  (ISO)
Chronic Hepatitis B  (ISO)
Chronic Hepatitis C  (ISO)
colon cancer  (ISO)
Corneal Graft Rejection  (ISO)
Coxsackievirus Infections  (ISO)
cryptococcal meningitis  (ISO)
cutaneous leishmaniasis  (ISO)
Disease Progression  (ISO)
Fungemia  (ISO)
Hepatic Echinococcosis  (ISO)
hepatitis C  (ISO)
hepatocellular carcinoma  (ISO)
herpes simplex  (ISO)
herpes simplex virus keratitis  (ISO)
histoplasmosis  (ISO)
human immunodeficiency virus infectious disease  (ISO)
influenza  (ISO)
Lung Neoplasms  (ISO)
lymphocytic choriomeningitis  (ISO)
lymphoma  (ISO)
Mammary Neoplasms, Experimental  (ISO)
nasal type extranodal NK/T-cell lymphoma  (ISO)
Neoplasm Metastasis  (ISO)
Neoplasms, Radiation-Induced  (ISO)
ovarian cancer  (ISO)
papillomavirus infectious disease  (ISO)
periodontitis  (ISO)
pre-eclampsia  (ISO)
primary progressive multiple sclerosis  (ISO)
pulmonary tuberculosis  (ISO)
rabies  (ISO)
Recurrence  (ISO)
Recurrent Respiratory Papillomatosis  (ISO)
respiratory syncytial virus infectious disease  (ISO)
Retroviridae Infections  (ISO)
Sepsis  (ISO)
Spinal Cord Injuries  (ISO)
stomach cancer  (ISO)
substance-related disorder  (ISO)
Thymus Neoplasms  (ISO)
toxic shock syndrome  (ISO)
Transplant Rejection  (ISO)
tuberculosis  (ISO)
Viral Bronchiolitis  (ISO)
viral encephalitis  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
CD274
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.195,454,391 - 5,474,452 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl95,454,391 - 5,474,402 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v095,269,270 - 5,289,629 (+)NCBIMhudiblu_PPA_v0panPan3
CD274
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl95,450,503 - 5,470,566 (+)EnsemblGRCh38hg38GRCh38
GRCh3895,450,542 - 5,470,554 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3795,450,542 - 5,470,554 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3695,440,559 - 5,458,477 (+)NCBINCBI36hg18NCBI36
Celera95,376,139 - 5,396,204 (+)NCBI
Cytogenetic Map9p24.1NCBI
HuRef95,406,210 - 5,426,274 (+)NCBIHuRef
CHM1_195,450,664 - 5,470,759 (+)NCBICHM1_1
Cd274
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391929,339,428 - 29,365,495 (+)NCBIGRCm39mm39
GRCm39 Ensembl1929,344,855 - 29,365,495 (+)Ensembl
GRCm381929,362,107 - 29,388,095 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1929,367,455 - 29,388,095 (+)EnsemblGRCm38mm10GRCm38
MGSCv371929,441,928 - 29,462,585 (+)NCBIGRCm37mm9NCBIm37
MGSCv361929,433,452 - 29,454,092 (+)NCBImm8
Celera1930,144,050 - 30,164,685 (+)NCBICelera
Cytogenetic Map19C1NCBI
Cd274
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21227,116,627 - 227,137,379 (+)NCBI
Rnor_6.0 Ensembl1247,519,939 - 247,537,943 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01247,519,890 - 247,539,659 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01254,768,528 - 254,788,292 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41233,053,607 - 233,065,384 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1224,273,306 - 224,285,083 (+)NCBICelera
Cytogenetic Map1q52NCBI
Cd274
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554349,487,315 - 9,505,904 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554349,487,309 - 9,508,366 (+)NCBIChiLan1.0ChiLan1.0
CD274
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1193,461,735 - 93,605,772 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl193,585,518 - 93,603,522 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha193,993,732 - 94,011,736 (+)NCBI
ROS_Cfam_1.0194,015,405 - 94,159,596 (+)NCBI
UMICH_Zoey_3.1193,771,527 - 93,789,533 (+)NCBI
UNSW_CanFamBas_1.0193,496,313 - 93,514,317 (+)NCBI
UU_Cfam_GSD_1.0194,260,510 - 94,278,519 (+)NCBI
Cd274
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947141,675,278 - 141,693,582 (+)NCBI
SpeTri2.0NW_004936539132,870 - 145,288 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CD274
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1216,660,047 - 216,792,724 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11216,646,378 - 216,792,731 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21242,395,402 - 242,416,220 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CD274
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11274,038,844 - 74,060,662 (-)NCBI
ChlSab1.1 Ensembl1274,041,767 - 74,056,806 (-)Ensembl
Vero_WHO_p1.0NW_02366603862,428,363 - 62,448,555 (-)NCBI
Cd274
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247369,991,851 - 10,017,047 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000045807   ⟹   ENSPPAP00000022990
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl95,454,391 - 5,474,402 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000045808   ⟹   ENSPPAP00000022991
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl95,459,981 - 5,471,771 (+)Ensembl
RefSeq Acc Id: XM_003823378   ⟹   XP_003823426
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.195,454,391 - 5,474,452 (+)NCBI
Mhudiblu_PPA_v095,269,275 - 5,289,629 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024930039   ⟹   XP_024785807
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.195,454,427 - 5,474,452 (+)NCBI
Mhudiblu_PPA_v095,269,270 - 5,289,629 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003823426 (Get FASTA)   NCBI Sequence Viewer  
  XP_024785807 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003823426   ⟸   XM_003823378
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_024785807   ⟸   XM_024930039
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSPPAP00000022991   ⟸   ENSPPAT00000045808
RefSeq Acc Id: ENSPPAP00000022990   ⟸   ENSPPAT00000045807
Protein Domains
Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034663 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000022990 ENTREZGENE, UniProtKB/TrEMBL
  ENSPPAP00000022991 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000045807 UniProtKB/TrEMBL
  ENSPPAT00000045808 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro CD80_C2-set UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
KEGG Report pps:100984141 UniProtKB/TrEMBL
NCBI Gene CD274 ENTREZGENE
Pfam C2-set_2 UniProtKB/TrEMBL
  V-set UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A2R9B063_PANPA UniProtKB/TrEMBL
  A0A2R9B0E1_PANPA UniProtKB/TrEMBL