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Gene: BIRC3 (baculoviral IAP repeat containing 3) Homo sapiens
Symbol: BIRC3
Name: baculoviral IAP repeat containing 3
Description: Exhibits ubiquitin-protein transferase activity. Involved in positive regulation of protein ubiquitination; regulation of apoptotic process; and regulation of necroptotic process. Localizes to the cytosol and nucleoplasm. Biomarker of renal cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AIP1; API2; apoptosis inhibitor 2; baculoviral IAP repeat-containing 3; baculoviral IAP repeat-containing protein 3; c-IAP2; cellular inhibitor of apoptosis 2; CIAP2; HAIP1; HIAP1; IAP homolog C; IAP-1; inhibitor of apoptosis protein 1; MALT2; mammalian IAP homolog C; MIHC; RING finger protein 49; RING-type E3 ubiquitin transferase BIRC3; RNF49; TNFR2-TRAF signaling complex protein; TNFR2-TRAF-signaling complex protein 1
Mus musculus (house mouse) : Birc3 (baculoviral IAP repeat-containing 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Birc3 (baculoviral IAP repeat-containing 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Birc3 (baculoviral IAP repeat containing 3)
Pan paniscus (bonobo/pygmy chimpanzee) : BIRC3 (baculoviral IAP repeat containing 3)
Canis lupus familiaris (dog) : BIRC3 (baculoviral IAP repeat containing 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Birc3 (baculoviral IAP repeat containing 3)
Sus scrofa (pig) : BIRC3 (baculoviral IAP repeat containing 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh3811102,317,373 - 102,339,403 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711102,188,181 - 102,210,134 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611101,693,404 - 101,713,675 (+)NCBINCBI36hg18NCBI36
Build 3411101,693,403 - 101,713,674NCBI
Celera1199,349,739 - 99,370,012 (+)NCBI
Cytogenetic Map11q22.2NCBI
HuRef1198,114,738 - 98,136,703 (+)NCBIHuRef
CHM1_111102,071,142 - 102,093,097 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on BIRC3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732624
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.