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Gene: BIRC3 (baculoviral IAP repeat containing 3) Homo sapiens
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Symbol: BIRC3
Name: baculoviral IAP repeat containing 3
Description: Exhibits ubiquitin-protein transferase activity. Involved in positive regulation of protein ubiquitination; regulation of apoptotic process; and regulation of necroptotic process. Localizes to the cytosol and nucleoplasm. Biomarker of renal cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AIP1; API2; apoptosis inhibitor 2; baculoviral IAP repeat-containing 3; baculoviral IAP repeat-containing protein 3; c-IAP2; cellular inhibitor of apoptosis 2; CIAP2; HAIP1; HIAP1; IAP homolog C; IAP-1; inhibitor of apoptosis protein 1; MALT2; mammalian IAP homolog C; MIHC; RING finger protein 49; RING-type E3 ubiquitin transferase BIRC3; RNF49; TNFR2-TRAF signaling complex protein; TNFR2-TRAF-signaling complex protein 1
Orthologs:
Mus musculus (house mouse) : Birc3 (baculoviral IAP repeat-containing 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Birc3 (baculoviral IAP repeat-containing 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Birc3 (baculoviral IAP repeat containing 3)
Pan paniscus (bonobo/pygmy chimpanzee) : BIRC3 (baculoviral IAP repeat containing 3)
Canis lupus familiaris (dog) : BIRC3 (baculoviral IAP repeat containing 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Birc3 (baculoviral IAP repeat containing 3)
Sus scrofa (pig) : BIRC3 (baculoviral IAP repeat containing 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811102,317,373 - 102,339,403 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711102,188,181 - 102,210,134 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611101,693,404 - 101,713,675 (+)NCBINCBI36hg18NCBI36
Build 3411101,693,403 - 101,713,674NCBI
Celera1199,349,739 - 99,370,012 (+)NCBI
Cytogenetic Map11q22.2NCBI
HuRef1198,114,738 - 98,136,703 (+)NCBIHuRef
CHM1_111102,071,142 - 102,093,097 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on BIRC3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732624
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.