CYP27B1 (cytochrome P450 family 27 subfamily B member 1) - Rat Genome Database

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Gene: CYP27B1 (cytochrome P450 family 27 subfamily B member 1) Canis lupus familiaris
Analyze
Symbol: CYP27B1
Name: cytochrome P450 family 27 subfamily B member 1
RGD ID: 12147645
Description: ENCODES a protein that exhibits calcidiol 1-monooxygenase activity (ortholog); secalciferol 1-monooxygenase activity (ortholog); INVOLVED IN aging (ortholog); bone mineralization (ortholog); calcitriol biosynthetic process from calciol (ortholog); ASSOCIATED WITH Acidoses (ortholog); acute kidney failure (ortholog); autosomal dominant hypocalcemia (ortholog); FOUND IN cytoplasm (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial; cytochrome P450, family 27, subfamily B, polypeptide 1; LOW QUALITY PROTEIN: 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1101,825,224 - 1,830,845 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl101,826,046 - 1,829,911 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha101,888,246 - 1,893,920 (-)NCBI
ROS_Cfam_1.0101,834,457 - 1,840,136 (-)NCBI
UMICH_Zoey_3.1101,812,161 - 1,817,832 (-)NCBI
UNSW_CanFamBas_1.0102,054,207 - 2,059,882 (-)NCBI
UU_Cfam_GSD_1.0102,179,134 - 2,184,808 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
mitochondrion  (ISO)

Molecular Function

References

Genomics

Comparative Map Data
CYP27B1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1101,825,224 - 1,830,845 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl101,826,046 - 1,829,911 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha101,888,246 - 1,893,920 (-)NCBI
ROS_Cfam_1.0101,834,457 - 1,840,136 (-)NCBI
UMICH_Zoey_3.1101,812,161 - 1,817,832 (-)NCBI
UNSW_CanFamBas_1.0102,054,207 - 2,059,882 (-)NCBI
UU_Cfam_GSD_1.0102,179,134 - 2,184,808 (-)NCBI
CYP27B1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1257,762,334 - 57,768,986 (-)EnsemblGRCh38hg38GRCh38
GRCh381257,762,334 - 57,767,078 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371258,156,117 - 58,160,861 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361256,442,384 - 56,447,243 (-)NCBINCBI36hg18NCBI36
Build 341256,442,385 - 56,447,151NCBI
Celera1257,813,712 - 57,818,571 (-)NCBI
Cytogenetic Map12q14.1NCBI
HuRef1255,192,956 - 55,197,815 (-)NCBIHuRef
CHM1_11258,123,921 - 58,128,780 (-)NCBICHM1_1
Cyp27b1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910126,884,115 - 126,891,897 (+)NCBIGRCm39mm39
GRCm39 Ensembl10126,884,119 - 126,888,875 (+)Ensembl
GRCm3810127,048,246 - 127,054,884 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10127,048,250 - 127,053,006 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710126,485,302 - 126,490,062 (+)NCBIGRCm37mm9NCBIm37
MGSCv3610126,451,200 - 126,455,955 (+)NCBImm8
Celera10129,440,145 - 129,444,905 (+)NCBICelera
Cytogenetic Map10D3NCBI
Cyp27b1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2762,869,340 - 62,876,242 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl762,871,297 - 62,876,241 (+)Ensembl
Rnor_6.0770,333,150 - 70,340,006 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,335,061 - 70,340,005 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0770,512,763 - 70,517,707 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera760,014,507 - 60,019,451 (+)NCBICelera
Cytogenetic Map7q22NCBI
LOC102011841
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554585,472,404 - 5,477,001 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554585,472,404 - 5,477,001 (-)NCBIChiLan1.0ChiLan1.0
CYP27B1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11231,419,773 - 31,424,822 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1231,419,773 - 31,424,822 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01231,158,814 - 31,164,462 (+)NCBIMhudiblu_PPA_v0panPan3
LOC101978323
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494556,964,979 - 56,970,660 (+)NCBI
SpeTri2.0NW_0049366461,899,686 - 1,904,104 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYP27B1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl523,050,114 - 23,058,470 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1523,053,129 - 23,058,865 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CYP27B1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11153,675,704 - 53,681,372 (-)NCBI
ChlSab1.1 Ensembl1153,675,226 - 53,680,443 (-)Ensembl
Vero_WHO_p1.0NW_023666037192,280,050 - 192,285,176 (+)NCBI
LOC101700851
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462480210,176,865 - 10,181,725 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 1
Low 1 18 2 6 2 5 1 12 8 10 3
Below cutoff 4 5 4 4 4 5 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000000446   ⟹   ENSCAFP00000000406
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl101,826,046 - 1,829,911 (-)Ensembl
RefSeq Acc Id: XM_038487933   ⟹   XP_038343861
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1101,812,161 - 1,817,832 (-)NCBI
RefSeq Acc Id: XM_038549826   ⟹   XP_038405754
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0102,179,134 - 2,184,808 (-)NCBI
RefSeq Acc Id: XM_038613793   ⟹   XP_038469721
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0102,054,207 - 2,059,882 (-)NCBI
RefSeq Acc Id: XM_038679148   ⟹   XP_038535076
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0101,834,457 - 1,840,136 (-)NCBI
RefSeq Acc Id: XM_538254   ⟹   XP_538254
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1101,825,224 - 1,830,845 (-)NCBI
Dog10K_Boxer_Tasha101,888,246 - 1,893,920 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_038343861 (Get FASTA)   NCBI Sequence Viewer  
  XP_038405754 (Get FASTA)   NCBI Sequence Viewer  
  XP_038469721 (Get FASTA)   NCBI Sequence Viewer  
  XP_038535076 (Get FASTA)   NCBI Sequence Viewer  
  XP_538254 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_538254   ⟸   XM_538254
- Sequence:
RefSeq Acc Id: ENSCAFP00000000406   ⟸   ENSCAFT00000000446
RefSeq Acc Id: XP_038343861   ⟸   XM_038487933
RefSeq Acc Id: XP_038469721   ⟸   XM_038613793
RefSeq Acc Id: XP_038535076   ⟸   XM_038679148
RefSeq Acc Id: XP_038405754   ⟸   XM_038549826


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000000287 Ensembl, ENTREZGENE
NCBI Gene CYP27B1 ENTREZGENE
VGNC ID VGNC:50343 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-01-09 CYP27B1  cytochrome P450 family 27 subfamily B member 1    cytochrome P450, family 27, subfamily B, polypeptide 1  Symbol and/or name change 5135510 APPROVED