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Gene: Adar (adenosine deaminase, RNA-specific) Mus musculus
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Symbol: Adar
Name: adenosine deaminase, RNA-specific
Description: Exhibits double-stranded RNA adenosine deaminase activity. Involved in several processes, including immune system development; regulation of viral genome replication; and response to virus. Localizes to cytoplasm and nucleolus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome and dyschromatosis symmetrica hereditaria. Orthologous to human ADAR (adenosine deaminase RNA specific); PARTICIPATES IN microRNA pathway; influenza A pathway; measles pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,2',4,4'-Tetrabromodiphenyl ether; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Adar1; Adar1p110; Adar1p150; AV242451; double-stranded RNA-specific adenosine deaminase; DRADA; mZaADAR; RNA adenosine deaminase 1; RNA-specific adenosine deaminase p110 form; RNA-specific adenosine deaminase p150 form
Orthologs:
Homo sapiens (human) : ADAR (adenosine deaminase RNA specific)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Adar (adenosine deaminase, RNA-specific)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adar (adenosine deaminase RNA specific)
Pan paniscus (bonobo/pygmy chimpanzee) : ADAR (adenosine deaminase RNA specific)
Canis lupus familiaris (dog) : ADAR (adenosine deaminase RNA specific)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adar (adenosine deaminase RNA specific)
Sus scrofa (pig) : ADAR (adenosine deaminase RNA specific)
Chlorocebus sabaeus (African green monkey) : ADAR (adenosine deaminase RNA specific)
Heterocephalus glaber (naked mole-rat) : Adar (adenosine deaminase RNA specific)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl389,715,022 - 89,753,446 (+)EnsemblGRCm38mm10GRCm38
GRCm38389,714,469 - 89,753,455 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37389,518,944 - 89,557,377 (+)NCBIGRCm37mm9NCBIm37
MGSCv36389,800,987 - 89,839,372 (+)NCBImm8
Celera389,752,022 - 89,790,497 (+)NCBICelera
Cytogenetic Map3F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Adar
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732453
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.