Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: PRKCSH (protein kinase C substrate 80K-H) Homo sapiens
Analyze
Symbol: PRKCSH
Name: protein kinase C substrate 80K-H
Description: This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum. The encoded protein is an acidic phosphoprotein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: advanced glycation end-product receptor 2; AGE-binding receptor 2; AGE-R2; G19P1; GIIB; glucosidase 2 subunit beta; glucosidase II subunit beta; glucosidase II, beta subunit; hepatocystin; PCLD; PCLD1; PKCSH; PLD1; polycystic liver disease; protein kinase C substrate 60.1 kDa protein heavy chain; protein kinase C substrate, 80 Kda protein; VASAP-60
Orthologs:
Mus musculus (house mouse) : Prkcsh (protein kinase C substrate 80K-H)  MGI  Alliance
Rattus norvegicus (Norway rat) : Prkcsh (protein kinase C substrate 80K-H)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prkcsh (protein kinase C substrate 80K-H)
Pan paniscus (bonobo/pygmy chimpanzee) : PRKCSH (protein kinase C substrate 80K-H)
Canis lupus familiaris (dog) : PRKCSH (protein kinase C substrate 80K-H)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prkcsh (protein kinase C substrate 80K-H)
Sus scrofa (pig) : PRKCSH (protein kinase C substrate 80K-H)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381911,435,257 - 11,450,968 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371911,546,111 - 11,561,783 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361911,407,269 - 11,422,783 (+)NCBINCBI36hg18NCBI36
Build 341911,407,268 - 11,422,783NCBI
Celera1911,441,004 - 11,456,521 (+)NCBI
Cytogenetic Map19p13.2NCBI
HuRef1911,121,465 - 11,136,774 (+)NCBIHuRef
CHM1_11911,546,100 - 11,561,813 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PRKCSH
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320068
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.