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Gene: Ccr5 (chemokine (C-C motif) receptor 5) Mus musculus
Symbol: Ccr5
Name: chemokine (C-C motif) receptor 5
RGD ID: 733487
Description: Exhibits C-C chemokine binding activity and C-C chemokine receptor activity. Involved in defense response and negative regulation of macrophage apoptotic process. Localizes to external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Used to study Coronavirus infectious disease. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; West Nile fever; autoimmune disease (multiple); berylliosis; and sarcoidosis (multiple). Orthologous to human CCR5 (C-C motif chemokine receptor 5); PARTICIPATES IN interleukin-12 signaling pathway; endocytosis pathway; toxoplasmosis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AM4-7; C-C chemokine receptor type 5; C-C CKR-5; CC-CKR-5; CCR-5; CD195; chemokine (C-C) receptor 5; Cmkbr; Cmkbr5; MIP-1 alpha receptor
Homo sapiens (human) : CCR5 (C-C motif chemokine receptor 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ccr5 (C-C motif chemokine receptor 5)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CCR5 (C-C motif chemokine receptor 5)
Canis lupus familiaris (dog) : CCR5 (C-C motif chemokine receptor 5)
Sus scrofa (pig) : CCR5 (chemokine (C-C motif) receptor 5)
Chlorocebus sabaeus (African green monkey) : CCR5 (C-C motif chemokine receptor 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm399123,921,557 - 123,934,153 (+)NCBI
GRCm389124,121,543 - 124,127,183 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9124,121,543 - 124,147,699 (+)EnsemblGRCm38mm10GRCm38
MGSCv379124,036,282 - 124,041,922 (+)NCBIGRCm37mm9NCBIm37
Celera9124,872,533 - 124,878,180 (-)NCBICelera
Cytogenetic Map9F4NCBI
cM Map975.05NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ccr5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733487
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.