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Gene: Ccr5 (chemokine (C-C motif) receptor 5) Mus musculus
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Symbol: Ccr5
Name: chemokine (C-C motif) receptor 5
RGD ID: 733487
Description: Exhibits C-C chemokine binding activity and C-C chemokine receptor activity. Involved in defense response and negative regulation of macrophage apoptotic process. Localizes to external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Used to study Coronavirus infectious disease. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; West Nile fever; autoimmune disease (multiple); berylliosis; and sarcoidosis (multiple). Orthologous to human CCR5 (C-C motif chemokine receptor 5); PARTICIPATES IN interleukin-12 signaling pathway; endocytosis pathway; toxoplasmosis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AM4-7; C-C chemokine receptor type 5; C-C CKR-5; CC-CKR-5; CCR-5; CD195; chemokine (C-C) receptor 5; Cmkbr; Cmkbr5; MIP-1 alpha receptor
Orthologs:
Homo sapiens (human) : CCR5 (C-C motif chemokine receptor 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ccr5 (C-C motif chemokine receptor 5)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CCR5 (C-C motif chemokine receptor 5)
Canis lupus familiaris (dog) : CCR5 (C-C motif chemokine receptor 5)
Sus scrofa (pig) : CCR5 (chemokine (C-C motif) receptor 5)
Chlorocebus sabaeus (African green monkey) : CCR5 (C-C motif chemokine receptor 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399123,921,557 - 123,934,153 (+)NCBI
GRCm389124,121,543 - 124,127,183 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9124,121,543 - 124,147,699 (+)EnsemblGRCm38mm10GRCm38
MGSCv379124,036,282 - 124,041,922 (+)NCBIGRCm37mm9NCBIm37
Celera9124,872,533 - 124,878,180 (-)NCBICelera
Cytogenetic Map9F4NCBI
cM Map975.05NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ccr5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733487
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.