MIR455 (microRNA mir-455) - Rat Genome Database

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Gene: MIR455 (microRNA mir-455) Canis lupus familiaris
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Symbol: MIR455
Name: microRNA mir-455
RGD ID: 12385864
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: cfa-mir-455; microRNA 455
RGD Orthologs
Human
Mouse
Rat
Pig
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11168,461,911 - 68,461,968 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1168,461,896 - 68,461,983 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1166,864,258 - 66,864,315 (+)NCBI
ROS_Cfam_1.01169,585,477 - 69,585,534 (+)NCBI
UMICH_Zoey_3.11168,101,107 - 68,101,164 (+)NCBI
UNSW_CanFamBas_1.01168,132,141 - 68,132,198 (+)NCBI
UU_Cfam_GSD_1.01168,871,375 - 68,871,432 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
RISC complex  (ISO)

References
Additional References at PubMed
PMID:16381832   PMID:18392026  


Genomics

Comparative Map Data
MIR455
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11168,461,911 - 68,461,968 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1168,461,896 - 68,461,983 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1166,864,258 - 66,864,315 (+)NCBI
ROS_Cfam_1.01169,585,477 - 69,585,534 (+)NCBI
UMICH_Zoey_3.11168,101,107 - 68,101,164 (+)NCBI
UNSW_CanFamBas_1.01168,132,141 - 68,132,198 (+)NCBI
UU_Cfam_GSD_1.01168,871,375 - 68,871,432 (+)NCBI
MIR455
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl9114,209,434 - 114,209,529 (+)EnsemblGRCh38hg38GRCh38
GRCh389114,209,434 - 114,209,529 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379116,971,714 - 116,971,809 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369116,011,534 - 116,011,629 (+)NCBINCBI36hg18NCBI36
Celera987,619,629 - 87,619,724 (+)NCBI
Cytogenetic Map9q32NCBI
HuRef986,578,236 - 86,578,331 (+)NCBIHuRef
CHM1_19117,118,235 - 117,118,330 (+)NCBICHM1_1
Mir455
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39463,175,088 - 63,175,169 (+)NCBIGRCm39mm39
GRCm39 Ensembl463,175,088 - 63,175,169 (+)Ensembl
GRCm38463,256,851 - 63,256,932 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl463,256,851 - 63,256,932 (+)EnsemblGRCm38mm10GRCm38
MGSCv37462,917,885 - 62,917,966 (+)NCBIGRCm37mm9NCBIm37
Celera461,913,734 - 61,913,815 (+)NCBICelera
Cytogenetic Map4B3NCBI
Mir455
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2576,689,313 - 76,689,390 (+)NCBImRatBN7.2
Rnor_6.0 Ensembl579,097,208 - 79,097,285 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0579,097,208 - 79,097,285 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0583,211,456 - 83,211,533 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera575,623,186 - 75,623,263 (+)NCBICelera
Cytogenetic Map5q24NCBI
MIR455
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1254,824,196 - 254,824,291 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11254,824,200 - 254,824,279 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21286,017,379 - 286,017,458 (+)NCBISscrofa10.2Sscrofa10.2susScr3


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system nervous system
High
Medium
Low 2 1 1 1 1 2
Below cutoff 1 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000039927
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1168,461,896 - 68,461,983 (+)Ensembl
RefSeq Acc Id: NR_049230
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11168,461,911 - 68,461,968 (+)NCBI
Dog10K_Boxer_Tasha1166,864,258 - 66,864,315 (+)NCBI
ROS_Cfam_1.01169,585,477 - 69,585,534 (+)NCBI
UMICH_Zoey_3.11168,101,107 - 68,101,164 (+)NCBI
UNSW_CanFamBas_1.01168,132,141 - 68,132,198 (+)NCBI
UU_Cfam_GSD_1.01168,871,375 - 68,871,432 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000025644 Ensembl, ENTREZGENE
Ensembl Transcript ENSCAFT00000039927 ENTREZGENE
miRBase MI0007999 ENTREZGENE
NCBI Gene MIR455 ENTREZGENE
RNAcentral URS00000AD002 RNACentral
  URS00007E501B RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR455  microRNA mir-455    microRNA 455  Symbol and/or name change 5135510 APPROVED