Stat2 (signal transducer and activator of transcription 2) - Rat Genome Database

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Gene: Stat2 (signal transducer and activator of transcription 2) Mus musculus
Analyze
Symbol: Stat2
Name: signal transducer and activator of transcription 2
RGD ID: 1323218
MGI Page MGI
Description: Predicted to have several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; identical protein binding activity; and ubiquitin-like protein ligase binding activity. Involved in type I interferon signaling pathway. Localizes to cytoplasm and nucleus. Is expressed in several structures, including central nervous system; early conceptus; and genitourinary system. Human ortholog(s) of this gene implicated in immunodeficiency 44. Orthologous to human STAT2 (signal transducer and activator of transcription 2); PARTICIPATES IN interleukin-27 signaling pathway; hepatitis C pathway; influenza A pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1600010G07Rik; AW496480
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910128,106,367 - 128,128,722 (+)NCBIGRCm39mm39
GRCm39 Ensembl10128,106,428 - 128,128,718 (+)Ensembl
GRCm3810128,270,498 - 128,292,853 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,270,559 - 128,292,849 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710127,707,632 - 127,729,905 (+)NCBIGRCm37mm9NCBIm37
MGSCv3610127,673,525 - 127,695,798 (+)NCBImm8
Celera10130,656,386 - 130,681,169 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1076.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
2-naphthylamine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-methylcholanthrene  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
aconitine  (ISO)
acrylamide  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (ISO)
carbon nanotube  (EXP)
cisplatin  (ISO)
clopidogrel  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (EXP)
dibutyl phthalate  (ISO)
diethylstilbestrol  (ISO)
doxorubicin  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
furan  (ISO)
gentamycin  (ISO)
geraniol  (ISO)
GW 4064  (EXP)
hydroxytyrosol  (ISO)
kaempferol  (ISO)
lipopolysaccharide  (EXP,ISO)
methyl methanesulfonate  (ISO)
monosodium L-glutamate  (EXP)
N-nitrosodiethylamine  (ISO)
nefazodone  (ISO)
nickel atom  (ISO)
nicotine  (ISO)
oxaliplatin  (ISO)
paracetamol  (ISO)
pentachlorophenol  (EXP)
pirinixic acid  (EXP,ISO)
poly(I:C)  (ISO)
poly(vinylpyrrolidone)  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
silicon dioxide  (EXP)
silver atom  (EXP,ISO)
silver(0)  (EXP,ISO)
sodium fluoride  (EXP)
succimer  (ISO)
sunitinib  (ISO)
T-2 toxin  (EXP,ISO)
tamoxifen  (EXP)
testosterone  (EXP)
tetrachloromethane  (ISO)
tetraphene  (EXP)
titanium dioxide  (EXP)
tofacitinib  (ISO)
topotecan  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
vitamin E  (ISO)
zidovudine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Ashour J, etal., Cell Host Microbe. 2010 Nov 18;8(5):410-21. doi: 10.1016/j.chom.2010.10.007.
2. Elsaesser HJ, etal., Proc Natl Acad Sci U S A. 2020 Mar 10;117(10):5420-5429. doi: 10.1073/pnas.1913776117. Epub 2020 Feb 24.
3. Gopal R, etal., Front Immunol. 2018 Sep 25;9:2151. doi: 10.3389/fimmu.2018.02151. eCollection 2018.
4. Gorman MJ, etal., Cell Host Microbe. 2018 May 9;23(5):672-685.e6. doi: 10.1016/j.chom.2018.04.003.
5. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
6. Hahm B, etal., Immunity. 2005 Feb;22(2):247-57. doi: 10.1016/j.immuni.2005.01.005.
7. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
8. Le-Trilling VTK, etal., J Virol. 2018 Jun 29;92(14). pii: JVI.00296-18. doi: 10.1128/JVI.00296-18. Print 2018 Jul 15.
9. Li W, etal., J Virol. 2014 Jul;88(13):7578-88. doi: 10.1128/JVI.03117-13. Epub 2014 Apr 23.
10. MGD data from the GO Consortium
11. MGD IEA
12. Miorin L, etal., J Virol. 2019 Jun 28;93(14). pii: JVI.00151-19. doi: 10.1128/JVI.00151-19. Print 2019 Jul 15.
13. Murray PJ J Immunol. 2007 Mar 1;178(5):2623-9.
14. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
15. OMIM Disease Annotation Pipeline
16. Perry ST, etal., PLoS Pathog. 2011 Feb;7(2):e1001297. doi: 10.1371/journal.ppat.1001297. Epub 2011 Feb 17.
17. Pipeline to import KEGG annotations from KEGG into RGD
18. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
19. RGD automated import pipeline
20. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
21. RGD automated import pipeline for gene-chemical interactions
22. Song H, etal., J Immunol. 2019 Apr 15;202(8):2266-2275. doi: 10.4049/jimmunol.1800848. Epub 2019 Mar 6.
23. Sun SL, etal., Clin Exp Pharmacol Physiol. 2007 Nov;34(11):1097-101.
24. Sung PS, etal., Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):10443-8. doi: 10.1073/pnas.1513341112. Epub 2015 Jul 27.
25. Tripathi S, etal., PLoS Pathog. 2017 Mar 9;13(3):e1006258. doi: 10.1371/journal.ppat.1006258. eCollection 2017 Mar.
26. Wada M, etal., J Viral Hepat. 2009 Jun;16(6):388-96. doi: 10.1111/j.1365-2893.2009.01095.x. Epub 2009 Feb 5.
27. Wang Y, etal., Cell Res. 2021 Feb;31(2):206-218. doi: 10.1038/s41422-020-0386-6. Epub 2020 Aug 5.
28. Yoshikawa R, etal., J Virol. 2019 May 1;93(10). pii: JVI.02226-18. doi: 10.1128/JVI.02226-18. Print 2019 May 15.
Additional References at PubMed
PMID:8530075   PMID:8601453   PMID:8626752   PMID:8889548   PMID:9126479   PMID:9287210   PMID:9342212   PMID:9638363   PMID:9695817   PMID:10200816   PMID:10349636   PMID:10464260  
PMID:10518610   PMID:10526573   PMID:10675904   PMID:10817963   PMID:10881177   PMID:10922068   PMID:11042159   PMID:11071526   PMID:11076861   PMID:11163195   PMID:11786546   PMID:12167251  
PMID:12477932   PMID:12540842   PMID:12634107   PMID:12904583   PMID:12925694   PMID:14610273   PMID:15102471   PMID:15611252   PMID:15782199   PMID:15850655   PMID:15919906   PMID:15921521  
PMID:15964802   PMID:16014513   PMID:16141072   PMID:16141073   PMID:16602821   PMID:17015705   PMID:17579067   PMID:17709541   PMID:17846149   PMID:18234692   PMID:18287559   PMID:18771758  
PMID:18774582   PMID:18799693   PMID:18835816   PMID:18981150   PMID:19272190   PMID:19386709   PMID:20059953   PMID:20211142   PMID:20233899   PMID:20412781   PMID:20637660   PMID:21267068  
PMID:21383239   PMID:21698215   PMID:21873635   PMID:22305621   PMID:22496215   PMID:23653476   PMID:23797472   PMID:23798382   PMID:23963652   PMID:23986597   PMID:24069548   PMID:24216477  
PMID:24302573   PMID:24598055   PMID:24895110   PMID:25024400   PMID:25564224   PMID:25918247   PMID:26019270   PMID:26059829   PMID:26146080   PMID:26335850   PMID:26764350   PMID:26817845  
PMID:27206766   PMID:27233962   PMID:27701741   PMID:27780205   PMID:27802159   PMID:28165510   PMID:28213522   PMID:28378742   PMID:28442624   PMID:29176737   PMID:29242538   PMID:29317535  
PMID:30134157   PMID:30385750   PMID:30517866   PMID:30737148   PMID:31266943   PMID:31484074   PMID:31619669   PMID:31708097   PMID:31730616   PMID:32506441   PMID:32522833   PMID:32635475  


Genomics

Comparative Map Data
Stat2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910128,106,367 - 128,128,722 (+)NCBIGRCm39mm39
GRCm39 Ensembl10128,106,428 - 128,128,718 (+)Ensembl
GRCm3810128,270,498 - 128,292,853 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,270,559 - 128,292,849 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710127,707,632 - 127,729,905 (+)NCBIGRCm37mm9NCBIm37
MGSCv3610127,673,525 - 127,695,798 (+)NCBImm8
Celera10130,656,386 - 130,681,169 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1076.5NCBI
STAT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1256,341,597 - 56,360,167 (-)EnsemblGRCh38hg38GRCh38
GRCh381256,341,597 - 56,360,161 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371256,735,381 - 56,753,891 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361255,021,648 - 55,040,176 (-)NCBINCBI36hg18NCBI36
Build 341255,021,650 - 55,040,176NCBI
Celera1256,388,733 - 56,407,397 (-)NCBI
Cytogenetic Map12q13.3NCBI
HuRef1253,774,045 - 53,793,077 (-)NCBIHuRef
CHM1_11256,702,765 - 56,721,407 (-)NCBICHM1_1
Stat2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27702,565 - 718,349 (+)NCBI
Rnor_6.0 Ensembl72,691,369 - 2,707,741 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.072,691,064 - 2,707,530 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.072,669,952 - 2,685,673 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,564,385 - 1,580,652 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.171,564,384 - 1,580,651 (+)NCBI
Celera7578,845 - 593,799 (+)NCBICelera
Cytogenetic Map7q11NCBI
Stat2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554583,952,738 - 3,970,668 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554583,953,019 - 3,973,151 (-)NCBIChiLan1.0ChiLan1.0
STAT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11232,808,586 - 32,827,732 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1232,808,586 - 32,827,732 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01232,555,523 - 32,574,137 (+)NCBIMhudiblu_PPA_v0panPan3
STAT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.110641,543 - 660,882 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl10642,718 - 658,546 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha10704,962 - 724,101 (-)NCBI
ROS_Cfam_1.010650,365 - 669,707 (-)NCBI
UMICH_Zoey_3.110627,617 - 646,943 (-)NCBI
UNSW_CanFamBas_1.010870,771 - 890,099 (-)NCBI
UU_Cfam_GSD_1.010994,493 - 1,013,823 (-)NCBI
Stat2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494558,106,734 - 58,122,062 (+)NCBI
SpeTri2.0NW_004936646747,178 - 763,449 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STAT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl521,733,035 - 21,751,354 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1521,733,030 - 21,748,960 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2523,280,591 - 23,294,360 (-)NCBISscrofa10.2Sscrofa10.2susScr3
STAT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11152,297,890 - 52,316,089 (-)NCBI
ChlSab1.1 Ensembl1152,297,543 - 52,316,105 (-)Ensembl
Vero_WHO_p1.0NW_023666037193,669,493 - 193,688,727 (+)NCBI
Stat2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462480211,645,851 - 11,662,812 (+)NCBI

Position Markers
AI255964  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3810128,270,001 - 128,270,105UniSTSGRCm38
MGSCv3710127,707,057 - 127,707,161UniSTSGRCm37
Celera10130,655,811 - 130,655,915UniSTS
Cytogenetic Map10D3UniSTS
cM Map1073.0UniSTS
cM Map1070.0UniSTS
Whitehead/MRC_RH101375.67UniSTS
AW496480  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3810128,291,874 - 128,291,965UniSTSGRCm38
MGSCv3710127,728,930 - 127,729,021UniSTSGRCm37
Celera10130,680,188 - 130,680,279UniSTS
Cytogenetic Map10D3UniSTS
cM Map1070.0UniSTS
Whitehead/MRC_RH101379.13UniSTS
UniSTS:236485  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3810128,292,083 - 128,292,369UniSTSGRCm38
MGSCv3710127,729,139 - 127,729,425UniSTSGRCm37
Celera10130,680,397 - 130,680,689UniSTS
Cytogenetic Map10D3UniSTS
cM Map1070.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226772Tibl13_mtibia length 13, 10 week (mouse)1019000000129800000Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039300000129800000Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039300000129800000Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069900000132500000Mouse
4142461Bmd25_mbone mineral density 25 (mouse)Not determined1097381196130694993Mouse
1357544Vtbt10_mvertebral trabecular bone trait 10 (mouse)Not determined1097381196130694993Mouse
11533919Mvb4_mmodifier of vibrator 4 (mouse)397381196130694993Mouse
11533921Mvb2_mmodifier of vibrator 2 (mouse)1097381196130694993Mouse
12880413V125Dq9_mvitamin D active form serum level QTL 9 (mouse)1097700000130694993Mouse
4141402T2dm1sa_mtype 2 diabetes mellitus 1 in SMXA RI mice (mouse)Not determined97922739130694993Mouse
11040593Lmr5e_mleishmaniasis resistance 5e (mouse)1099384730130694993Mouse
11040595Lmr5c_mleishmaniasis resistance 5c (mouse)1099384730130694993Mouse
11040597Lmr5a_mleishmaniasis resistance 5a (mouse)1099384730130694993Mouse
1301968Estq4_mestradiol regulated response QTL 4 (mouse)Not determined10101150611130694993Mouse
1357744Cfbw4_mcystic fibrosis body weight 4 (mouse)Not determined10101150611130694993Mouse
1301901Im5_mimmunoregulatory 5 (mouse)Not determined10101661259130694993Mouse
4141361Cfmq3_mcystic fibrosis modifier QTL 3 (mouse)Not determined10101661259130694993Mouse
1300678Leg2_mlongevity extending gene 2 (mouse)Not determined10102671003130694993Mouse
1301895Exq1_mexploratory and excitability QTL 1 (mouse)Not determined10103011947130694993Mouse
14696727Kidrq2_mkidney weight, right QTL 2 (mouse)10103066603130694993Mouse
4141007Obrq10_mobesity resistance QTL 10 (mouse)Not determined103407822130694993Mouse
4141487Tgq21_mtriglyceride QTL 21 (mouse)Not determined104274116130694993Mouse
14746996Manh69_mmandible shape 69 (mouse)10104927733130694993Mouse
1357482Nhdlq4_mnon-HDL QTL 4 (mouse)Not determined10105205399130694993Mouse
1300679Nociq2_mnociceptive sensitivity inflammatory QTL 2 (mouse)Not determined10105205399130694993Mouse
1302200Sle12_msystematic lupus erythematosus susceptibility 12 (mouse)Not determined10105205399130694993Mouse
11040594Lmr5f_mleishmaniasis resistance 5f (mouse)10105343808130694993Mouse
11040596Lmr5d_mleishmaniasis resistance 5d (mouse)10105343808130694993Mouse
11040598Lmr5b_mleishmaniasis resistance 5b (mouse)10105343808130694993Mouse
4142089Obrq9_mobesity resistance QTL 9 (mouse)Not determined108680038130694993Mouse
4141153Ltgq2_mliver triglyceride QTL 2 (mouse)Not determined108680038130694993Mouse
11039496Ltpr5b_mLeishmania tropica response 5b (mouse)10108739225130694993Mouse
11041664Lmr25_mleishmaniasis resistance 25 (mouse)10108739225130694993Mouse
11049563Lmr25a_mleishmaniasis resistance 25a (mouse)10108739225130694993Mouse
11049570Lmr25b_mleishmaniasis resistance 25b (mouse)10108739225130694993Mouse
12911218Frct3a_mfear conditioning traits 3a (mouse)10122950065129631127Mouse
12911220Frct3c_mfear conditioning traits 3c (mouse)10122950065129631127Mouse
12879490Frct3_mfear conditioning traits 3 (mouse)10122950065129631127Mouse
12904001Opfaq10_mopen field activity QTL 10 (mouse)10125797802129630506Mouse
12911219Frct3b_mfear conditioning traits 3b (mouse)10127839705129631127Mouse
12911221Frct3d_mfear conditioning traits 3d (mouse)10127839705129631127Mouse
12904000Opfaq7_mopen field activity QTL 7 (mouse)10127910449129630506Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1070
Count of miRNA genes:388
Interacting mature miRNAs:441
Transcripts:ENSMUST00000085708, ENSMUST00000105238
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000085708   ⟹   ENSMUSP00000082855
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl10128,270,576 - 128,292,849 (+)Ensembl
RefSeq Acc Id: ENSMUST00000105238   ⟹   ENSMUSP00000100872
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl10128,270,576 - 128,292,849 (+)Ensembl
RefSeq Acc Id: ENSMUST00000217727
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl10128,282,817 - 128,283,960 (+)Ensembl
RefSeq Acc Id: ENSMUST00000217852
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl10128,277,858 - 128,281,602 (+)Ensembl
RefSeq Acc Id: ENSMUST00000218862
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl10128,283,570 - 128,291,797 (+)Ensembl
RefSeq Acc Id: ENSMUST00000218863
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl10128,270,559 - 128,277,410 (+)Ensembl
RefSeq Acc Id: ENSMUST00000220142
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl10128,281,648 - 128,283,293 (+)Ensembl
RefSeq Acc Id: ENSMUST00000220277
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl10128,284,107 - 128,290,712 (+)Ensembl
RefSeq Acc Id: NM_019963   ⟹   NP_064347
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910128,106,367 - 128,128,722 (+)NCBI
GRCm3810128,270,498 - 128,292,853 (+)NCBI
MGSCv3710127,707,632 - 127,729,905 (+)RGD
Celera10130,656,386 - 130,681,169 (+)RGD
cM Map10 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_064347   ⟸   NM_019963
- UniProtKB: Q9QXJ2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000100872   ⟸   ENSMUST00000105238
RefSeq Acc Id: ENSMUSP00000082855   ⟸   ENSMUST00000085708
Protein Domains
SH2   STAT2_C

Promoters
RGD ID:6819964
Promoter ID:MM_KWN:5980
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000105238,   NM_019963
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3610127,706,696 - 127,707,722 (+)MPROMDB
RGD ID:6819966
Promoter ID:MM_KWN:5981
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Liver,   Lung
Transcripts:UC007HMB.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3610127,720,254 - 127,720,754 (+)MPROMDB
RGD ID:8673594
Promoter ID:EPDNEW_M14828
Type:initiation region
Name:Stat2_1
Description:Mus musculus signal transducer and activator of transcription2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3810128,270,557 - 128,270,617EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:103039 AgrOrtholog
Ensembl Genes ENSMUSG00000040033 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000082855 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000100872 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000085708 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000105238 UniProtKB/TrEMBL
Gene3D-CATH 1.10.532.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.630 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro p53-like_TF_DNA-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT2_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT2_SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT_TF_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT_TF_coiled-coil UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT_TF_DNA-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT_TF_DNA-bd_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT_TF_prot_interaction UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20847 UniProtKB/TrEMBL
MGD MGI:103039 ENTREZGENE
NCBI Gene 20847 ENTREZGENE
PANTHER PTHR11801 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT2_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT_bind UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT_int UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Stat2 PhenoGen
PROSITE SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAT_int UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47655 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48092 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49417 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55550 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt E9QJX9_MOUSE UniProtKB/TrEMBL
  Q3U5W1_MOUSE UniProtKB/TrEMBL
  Q3UDU1_MOUSE UniProtKB/TrEMBL
  Q6P1X8_MOUSE UniProtKB/TrEMBL
  Q8CD97_MOUSE UniProtKB/TrEMBL
  Q9CW17_MOUSE UniProtKB/TrEMBL
  Q9QXJ2 ENTREZGENE, UniProtKB/TrEMBL
  Q9QZE4_MOUSE UniProtKB/TrEMBL
  Q9WVL2 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q64188 UniProtKB/Swiss-Prot
  Q64189 UniProtKB/Swiss-Prot
  Q64250 UniProtKB/Swiss-Prot