Vdr (vitamin D receptor) - Rat Genome Database

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Gene: Vdr (vitamin D receptor) Ictidomys tridecemlineatus
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Symbol: Vdr
Name: vitamin D receptor
RGD ID: 12639717
Description: ENCODES a protein that exhibits calcitriol binding (ortholog); DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN aging (ortholog); animal organ morphogenesis (ortholog); apoptotic signaling pathway (ortholog); PARTICIPATES IN altered p53 signaling pathway; ASSOCIATED WITH Acute Hepatitis (ortholog); alopecia (ortholog); amyotrophic lateral sclerosis (ortholog); FOUND IN caveola (ortholog); cytosol (ortholog); dense fibrillar component (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: vitamin D (1,25- dihydroxyvitamin D3) receptor; vitamin D3 receptor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494567,363,831 - 67,424,087 (+)NCBI
SpeTri2.0NW_0049365125,741,836 - 5,800,999 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Hepatitis  (ISO)
alopecia  (ISO)
amyotrophic lateral sclerosis  (ISO)
aortic valve stenosis  (ISO)
asthma  (ISO)
atherosclerosis  (ISO)
atopic dermatitis  (ISO)
autism spectrum disorder  (ISO)
autoimmune hepatitis  (ISO)
autosomal recessive limb-girdle muscular dystrophy type 2B  (ISO)
B-Cell Chronic Lymphocytic Leukemia  (ISO)
Barrett's esophagus  (ISO)
basal cell carcinoma  (ISO)
Behcet's disease  (ISO)
breast cancer  (ISO)
Breast Neoplasms  (ISO)
Bronchopulmonary Dysplasia  (ISO)
cholangitis  (ISO)
Chronic Hepatitis C  (ISO)
Chronic Periodontitis  (ISO)
coronary artery disease  (ISO)
diabetes mellitus  (ISO)
diabetic retinopathy  (ISO)
disease of cellular proliferation  (ISO)
Dwarfism  (ISO)
erythema nodosum  (ISO)
esophagus adenocarcinoma  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Fabry disease  (ISO)
familial adenomatous polyposis  (ISO)
Familial Hypophosphatemic Rickets  (ISO)
fatty liver disease  (ISO)
Fetal Growth Retardation  (ISO)
genetic disease  (ISO)
Graves' disease  (ISO)
hepatitis B  (ISO)
hepatocellular carcinoma  (ISO)
human immunodeficiency virus infectious disease  (ISO)
Hypercalciuria  (ISO)
hypertension  (ISO)
Hypophosphatemic Rickets  (ISO)
Inflammation  (ISO)
Insulin Resistance  (ISO)
Lead Poisoning  (ISO)
leishmaniasis  (ISO)
liver cirrhosis  (ISO)
male breast cancer  (ISO)
Mammary Neoplasms, Experimental  (ISO)
melanoma  (ISO)
multiple sclerosis  (ISO)
Myocardial Reperfusion Injury  (ISO)
myopia  (ISO)
Neoplasm Metastasis  (ISO)
non-alcoholic fatty liver disease  (ISO)
osteoporosis  (ISO)
otosclerosis  (ISO)
Parathyroid Neoplasms  (ISO)
Parkinson's disease  (ISO)
peptic esophagitis  (ISO)
pneumonia  (ISO)
polycystic ovary syndrome  (ISO)
Postmenopausal Osteoporosis  (ISO)
primary biliary cholangitis  (ISO)
primary hyperparathyroidism  (ISO)
primary sclerosing cholangitis  (ISO)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
psoriasis  (ISO)
pulmonary tuberculosis  (ISO)
rheumatoid arthritis  (ISO)
rickets  (ISO)
secondary hyperparathyroidism  (ISO)
skin melanoma  (ISO)
Spinal Fractures  (ISO)
squamous cell carcinoma  (ISO)
Sunburn  (ISO)
Systemic Inflammatory Response Syndrome  (ISO)
temporal lobe epilepsy  (ISO)
transitional cell carcinoma  (ISO)
tuberculosis  (ISO)
Turner syndrome  (ISO)
uremia  (ISO)
Viral Bronchiolitis  (ISO)
Vitamin D Deficiency  (ISO)
vitamin D-dependent rickets  (ISO)
vitamin D-dependent rickets type 2A  (ISO)
vitiligo  (ISO)
Weight Gain  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Vdr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494567,363,831 - 67,424,087 (+)NCBI
SpeTri2.0NW_0049365125,741,836 - 5,800,999 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VDR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1247,841,537 - 47,943,048 (-)EnsemblGRCh38hg38GRCh38
GRCh381247,841,537 - 47,905,022 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371248,235,320 - 48,298,777 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361246,521,587 - 46,585,081 (-)NCBINCBI36hg18NCBI36
Build 341246,521,588 - 46,585,036NCBI
Celera1247,032,871 - 47,096,518 (-)NCBI
Cytogenetic Map12q13.11NCBI
HuRef1245,266,368 - 45,330,677 (-)NCBIHuRef
CHM1_11248,201,212 - 48,264,704 (-)NCBICHM1_1
Vdr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391597,752,308 - 97,806,177 (-)NCBIGRCm39mm39
GRCm39 Ensembl1597,752,306 - 97,808,511 (-)Ensembl
GRCm381597,854,427 - 97,908,296 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1597,854,425 - 97,910,630 (-)EnsemblGRCm38mm10GRCm38
MGSCv371597,684,858 - 97,738,727 (-)NCBIGRCm37mm9NCBIm37
MGSCv361597,682,461 - 97,736,330 (-)NCBImm8
Celera1599,981,938 - 100,035,599 (-)NCBICelera
Cytogenetic Map15F1NCBI
Vdr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27128,987,981 - 129,037,677 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl7139,342,063 - 139,394,166 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.07139,344,452 - 139,394,138 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07139,536,241 - 139,585,928 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47136,567,614 - 136,617,280 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17136,644,050 - 136,693,717 (-)NCBI
Celera7125,479,125 - 125,528,679 (-)NCBICelera
Cytogenetic Map7q36NCBI
Vdr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555006,745,678 - 6,798,048 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555006,745,725 - 6,798,052 (-)NCBIChiLan1.0ChiLan1.0
VDR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11241,661,688 - 41,766,192 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1241,702,742 - 41,766,192 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01240,828,413 - 40,891,700 (+)NCBIMhudiblu_PPA_v0panPan3
VDR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1276,852,915 - 6,909,466 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl276,852,723 - 6,909,470 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2739,397,549 - 39,454,181 (-)NCBI
ROS_Cfam_1.0276,920,266 - 6,976,964 (+)NCBI
UMICH_Zoey_3.1276,857,514 - 6,914,062 (+)NCBI
UNSW_CanFamBas_1.0276,892,693 - 6,949,518 (+)NCBI
UU_Cfam_GSD_1.02739,686,018 - 39,742,660 (-)NCBI
VDR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl578,205,810 - 78,267,321 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1578,205,807 - 78,266,505 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2581,279,217 - 81,338,475 (-)NCBISscrofa10.2Sscrofa10.2susScr3
VDR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11144,062,198 - 44,126,295 (-)NCBI
ChlSab1.1 Ensembl1144,065,457 - 44,166,684 (-)Ensembl
Vero_WHO_p1.0NW_023666037202,254,076 - 202,319,396 (+)NCBI
Vdr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248164,314,146 - 4,423,946 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_021726118   ⟹   XP_021581793
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494567,363,831 - 67,424,087 (+)NCBI
SpeTri2.0NW_0049365125,741,836 - 5,800,999 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040280749   ⟹   XP_040136683
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494567,365,074 - 67,424,087 (+)NCBI
RefSeq Acc Id: XM_040280750   ⟹   XP_040136684
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494567,388,350 - 67,424,087 (+)NCBI
RefSeq Acc Id: XM_040280751   ⟹   XP_040136685
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494567,365,074 - 67,424,087 (+)NCBI
RefSeq Acc Id: XM_040280752   ⟹   XP_040136686
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494567,363,877 - 67,424,087 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_021581793   ⟸   XM_021726118
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_040136686   ⟸   XM_040280752
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040136683   ⟸   XM_040280749
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040136685   ⟸   XM_040280751
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040136684   ⟸   XM_040280750
- Peptide Label: isoform X2
Protein Domains
NR LBD   Nuclear receptor


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000026741 ENTREZGENE
Ensembl Protein ENSSTOP00000031953 ENTREZGENE
NCBI Gene Vdr ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-05-09 Vdr  vitamin D receptor    vitamin D (1,25- dihydroxyvitamin D3) receptor  Symbol and/or name change 5135510 APPROVED