Stat4 (signal transducer and activator of transcription 4) - Rat Genome Database

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Gene: Stat4 (signal transducer and activator of transcription 4) Chinchilla lanigera
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Symbol: Stat4
Name: signal transducer and activator of transcription 4
RGD ID: 8823621
Description: ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); identical protein binding (ortholog); INVOLVED IN cellular response to organic substance (ortholog); cytokine-mediated signaling pathway (ortholog); hematopoietic stem cell homeostasis (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-23 signaling pathway; interleukin-27 signaling pathway; ASSOCIATED WITH asthma (ortholog); autoimmune hepatitis (ortholog); Behcet's disease (ortholog); FOUND IN nucleus (ortholog); RNA polymerase II transcription regulator complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554038,061,471 - 8,144,276 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554038,061,471 - 8,144,252 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISS annotations to Chinchilla, Squirrel, Bonobo and/or Dog genes from Human gene annotations
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline

Genomics

Comparative Map Data
Stat4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554038,061,471 - 8,144,276 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554038,061,471 - 8,144,252 (+)NCBIChiLan1.0ChiLan1.0
STAT4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382191,029,576 - 191,246,175 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2191,029,576 - 191,151,596 (-)EnsemblGRCh38hg38GRCh38
GRCh372191,894,302 - 192,016,322 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362191,602,551 - 191,724,170 (-)NCBINCBI36hg18NCBI36
Build 342191,719,811 - 191,841,431NCBI
Celera2185,488,908 - 185,610,548 (-)NCBI
Cytogenetic Map2q32.2-q32.3NCBI
HuRef2183,753,956 - 183,875,743 (-)NCBIHuRef
CHM1_12191,900,128 - 192,022,113 (-)NCBICHM1_1
T2T-CHM13v2.02191,518,699 - 191,640,702 (-)NCBI
Stat4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39152,026,265 - 52,146,348 (+)NCBIGRCm39mm39
GRCm39 Ensembl152,026,307 - 52,146,348 (+)Ensembl
GRCm38151,987,106 - 52,107,189 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl151,987,148 - 52,107,189 (+)EnsemblGRCm38mm10GRCm38
MGSCv37152,065,088 - 52,164,028 (+)NCBIGRCm37mm9NCBIm37
MGSCv36151,952,789 - 52,051,729 (+)NCBImm8
Celera152,546,764 - 52,645,629 (+)NCBICelera
Cytogenetic Map1C1.1NCBI
cM Map126.67NCBI
STAT4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B196,247,617 - 196,394,154 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B196,247,881 - 196,366,011 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B78,331,402 - 78,549,231 (-)NCBIMhudiblu_PPA_v0panPan3
STAT4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1371,566,563 - 1,685,378 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl371,566,585 - 1,829,894 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha372,514,598 - 2,633,404 (-)NCBI
ROS_Cfam_1.0371,453,968 - 1,572,676 (-)NCBI
ROS_Cfam_1.0 Ensembl371,453,990 - 1,550,821 (-)Ensembl
UMICH_Zoey_3.1371,463,313 - 1,581,898 (-)NCBI
UNSW_CanFamBas_1.0371,431,241 - 1,549,848 (-)NCBI
UU_Cfam_GSD_1.0371,459,885 - 1,578,875 (-)NCBI
Stat4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303149,652,139 - 149,767,224 (-)NCBI
SpeTri2.0NW_0049365067,091,982 - 7,185,938 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STAT4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1595,656,077 - 95,763,472 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11595,656,206 - 95,764,099 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215106,914,582 - 106,960,243 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.215107,069,138 - 107,073,997 (-)NCBISscrofa10.2Sscrofa10.2susScr3
STAT4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11076,553,626 - 76,708,540 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1076,553,606 - 76,674,928 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666040122,773,405 - 122,923,766 (+)NCBIVero_WHO_p1.0
Stat4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248544,976,507 - 5,057,391 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248544,975,724 - 5,056,940 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000016763   ⟹   ENSCLAP00000016599
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554038,061,471 - 8,144,276 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000016764   ⟹   ENSCLAP00000016600
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554038,064,457 - 8,143,979 (+)Ensembl
RefSeq Acc Id: XM_005373293   ⟹   XP_005373350
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554038,061,471 - 8,144,252 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005373294   ⟹   XP_005373351
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554038,061,859 - 8,144,252 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005373295   ⟹   XP_005373352
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554038,061,471 - 8,144,252 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005373350 (Get FASTA)   NCBI Sequence Viewer  
  XP_005373351 (Get FASTA)   NCBI Sequence Viewer  
  XP_005373352 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005373352   ⟸   XM_005373295
- Sequence:
RefSeq Acc Id: XP_005373350   ⟸   XM_005373293
- Sequence:
RefSeq Acc Id: XP_005373351   ⟸   XM_005373294
- Sequence:
RefSeq Acc Id: ENSCLAP00000016599   ⟸   ENSCLAT00000016763
RefSeq Acc Id: ENSCLAP00000016600   ⟸   ENSCLAT00000016764
Protein Domains
SH2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000011405 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCLAP00000016599 ENTREZGENE
  ENSCLAP00000016599.1 UniProtKB/TrEMBL
  ENSCLAP00000016600 ENTREZGENE
  ENSCLAP00000016600.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000016763 ENTREZGENE
  ENSCLAT00000016763.1 UniProtKB/TrEMBL
  ENSCLAT00000016764 ENTREZGENE
  ENSCLAT00000016764.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.532.10 UniProtKB/TrEMBL
  2.60.40.630 UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/TrEMBL
InterPro p53-like_TF_DNA-bd UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
  STAT UniProtKB/TrEMBL
  STAT4 UniProtKB/TrEMBL
  STAT4_SH2 UniProtKB/TrEMBL
  STAT_N_sf UniProtKB/TrEMBL
  STAT_TF_alpha UniProtKB/TrEMBL
  STAT_TF_coiled-coil UniProtKB/TrEMBL
  STAT_TF_DNA-bd UniProtKB/TrEMBL
  STAT_TF_DNA-bd_N UniProtKB/TrEMBL
  STAT_TF_prot_interaction UniProtKB/TrEMBL
NCBI Gene Stat4 ENTREZGENE
PANTHER PTHR11801 UniProtKB/TrEMBL
  PTHR11801:SF19 UniProtKB/TrEMBL
Pfam SH2 UniProtKB/TrEMBL
  STAT_alpha UniProtKB/TrEMBL
  STAT_bind UniProtKB/TrEMBL
  STAT_int UniProtKB/TrEMBL
PROSITE SH2 UniProtKB/TrEMBL
SMART STAT_int UniProtKB/TrEMBL
Superfamily-SCOP SSF47655 UniProtKB/TrEMBL
  SSF48092 UniProtKB/TrEMBL
  SSF49417 UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
UniProt A0A8C2YQV1_CHILA UniProtKB/TrEMBL
  A0A8C2YQV4_CHILA UniProtKB/TrEMBL