Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Stat4 (signal transducer and activator of transcription 4) Mus musculus
Analyze
Symbol: Stat4
Name: signal transducer and activator of transcription 4
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including cytokine-mediated signaling pathway; positive regulation of transcription by RNA polymerase II; and protein phosphorylation. Localizes to nucleus. Is expressed in several structures, including axial skeleton; cranium; early conceptus; genitourinary system; and thymus primordium. Used to study type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; IgA glomerulonephritis; autoimmune hypersensitivity disease (multiple); liver disease (multiple); and systemic scleroderma (multiple). Orthologous to human STAT4 (signal transducer and activator of transcription 4).
Type: protein-coding
RefSeq Status: REVIEWED
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl151,987,148 - 52,107,189 (+)EnsemblGRCm38mm10GRCm38
GRCm38151,987,106 - 52,107,189 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37152,065,088 - 52,164,028 (+)NCBIGRCm37mm9NCBIm37
MGSCv36151,952,789 - 52,051,729 (+)NCBImm8
Celera152,546,764 - 52,645,629 (+)NCBICelera
Cytogenetic Map1C1.1NCBI
cM Map126.67NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Stat4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1313965
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.