Ido1 (indoleamine 2,3-dioxygenase 1)

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Gene: Ido1 (indoleamine 2,3-dioxygenase 1) Mus musculus

Analyze

Symbol:

Ido1

Name:

indoleamine 2,3-dioxygenase 1

RGD ID:

731346

MGI Page

MGI

Description:

Enables tryptophan 2,3-dioxygenase activity. Acts upstream of or within several processes, including carboxylic acid metabolic process; regulation of apoptotic process; and regulation of cytokine production. Located in smooth muscle contractile fiber and stereocilium bundle. Is expressed in cerebral cortex; corpus striatum; embryo; extraembryonic component; and hippocampus. Used to study pre-eclampsia. Orthologous to human IDO1 (indoleamine 2,3-dioxygenase 1).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

I; Ido; IDO-1; Indo; indole 2,3-dioxygenase; indoleamine-pyrrole 2,3 dioxygenase; indoleamine-pyrrole 2,3-dioxygenase

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	IDO1 (indoleamine 2,3-dioxygenase 1)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Ido1 (indoleamine 2,3-dioxygenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ido1 (indoleamine 2,3-dioxygenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	IDO1 (indoleamine 2,3-dioxygenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	IDO1 (indoleamine 2,3-dioxygenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ido1 (indoleamine 2,3-dioxygenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	IDO1 (indoleamine 2,3-dioxygenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	IDO1 (indoleamine 2,3-dioxygenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ido1 (indoleamine 2,3-dioxygenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Ido1 (indoleamine 2,3-dioxygenase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	IDO1 (indoleamine 2,3-dioxygenase 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ido1 (indoleamine 2,3-dioxygenase 1)	Alliance	DIOPT (ZFIN)
Saccharomyces cerevisiae (baker's yeast):	BNA2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	25,074,148 - 25,086,987 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	25,074,152 - 25,087,025 (-)	Ensembl		GRCm39 Ensembl
GRCm38	8	24,584,133 - 24,596,952 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	24,584,136 - 24,597,009 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	25,694,613 - 25,707,481 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	26,049,686 - 26,062,554 (-)	NCBI		MGSCv36	mm8
Celera	8	26,068,313 - 26,081,132 (-)	NCBI		Celera
Cytogenetic Map	8	A2	NCBI
cM Map	8	12.76	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acquired immunodeficiency syndrome (ISO)

Acute Lung Injury (IMP)

Animal Toxoplasmosis (IMP)

B-lymphoblastic leukemia/lymphoma (ISO)

Breast Neoplasms (ISO)

chlamydia (IEP,ISO)

Chronic Hepatitis B (ISO)

Chronic Hepatitis C (ISO)

Cognitive Dysfunction (IMP)

dengue disease (ISO)

eczema herpeticum (ISO)

endometriosis (ISO)

Endotoxemia (IMP)

Experimental Liver Cirrhosis (IEP,IMP)

genetic disease (ISO)

hemophagocytic lymphohistiocytosis (IMP)

Inflammation (ISO)

Neoplasm Recurrence, Local (ISO)

neurodegenerative disease (ISO)

obesity (ISO)

paracoccidioidomycosis (IEP)

Pneumococcal Meningitis (IMP)

pneumonic tularemia (IMP)

pre-eclampsia (IAGP)

pulmonary tuberculosis (ISO)

Salmonella Infections, Animal (IMP)

Sepsis (IMP)

shigellosis (IDA)

Streptococcus pneumonia (IEP)

swine influenza (IMP)

Systemic Juvenile Rheumatoid Arthritis (IMP)

toxic shock syndrome (ISO)

viral encephalitis (IMP)

Viral Myocarditis (IMP)

vulvovaginal candidiasis (IMP)

Weight Gain (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-amphetamine (EXP)

1,2-dimethylhydrazine (EXP)

17beta-estradiol (EXP)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-tribromophenol (ISO)

2,4,6-trinitrobenzenesulfonic acid (EXP)

3',5'-cyclic AMP (ISO)

3,3',5,5'-tetrabromobisphenol A (EXP,ISO)

5-aza-2'-deoxycytidine (ISO)

acetylsalicylic acid (ISO)

acyclovir (ISO)

ammonium chloride (ISO)

anthranilic acid (EXP)

arsenite(3-) (ISO)

atrazine (ISO)

bazedoxifene (EXP)

belinostat (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

buta-1,3-diene (EXP)

butanal (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

cannabidiol (ISO)

carbon nanotube (ISO)

chromium(6+) (EXP)

cisplatin (ISO)

curcumin (ISO)

cyclophosphamide (ISO)

decabromodiphenyl ether (ISO)

dextran sulfate (EXP)

dorsomorphin (ISO)

entinostat (ISO)

ethanol (EXP)

gadodiamide hydrate (ISO)

hexachlorobenzene (EXP)

hyaluronic acid (ISO)

hydrogen peroxide (ISO)

Indeno[1,2,3-cd]pyrene (ISO)

indirubin-3'-monoxime (EXP)

indole-3-methanol (EXP)

indolin-2-one (ISO)

kynurenine (EXP)

L-tryptophan (EXP,ISO)

lasofoxifene (EXP)

lead diacetate (EXP)

lipopolysaccharide (EXP,ISO)

lithium atom (EXP)

lithium chloride (EXP)

lithium hydride (EXP)

malathion (ISO)

medroxyprogesterone acetate (ISO)

muramyl dipeptide (EXP)

N-nitrosodiethylamine (ISO)

neopterin (ISO)

nickel atom (ISO)

nickel sulfate (ISO)

nitric oxide (ISO)

nitroglycerin (ISO)

ozone (EXP,ISO)

paracetamol (EXP)

perfluorododecanoic acid (ISO)

phenethyl caffeate (ISO)

PhIP (ISO)

pirinixic acid (EXP)

poly(I:C) (ISO)

quercetin (ISO)

raloxifene (EXP)

resveratrol (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

Salinomycin (ISO)

SB 431542 (ISO)

simvastatin (ISO)

sulfasalazine (ISO)

temozolomide (ISO)

testosterone (EXP)

testosterone enanthate (ISO)

tetrachloromethane (EXP)

trichostatin A (ISO)

trimellitic anhydride (EXP)

valproic acid (EXP,ISO)

vinclozolin (ISO)

XL147 (EXP)

zinc atom (ISO)

zinc(0) (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

'de novo' NAD biosynthetic process from tryptophan (IBA)

defense response (TAS)

immune system process (IEA)

inflammatory response (IMP)

kynurenic acid biosynthetic process (IMP)

multicellular organismal response to stress (IMP)

negative regulation of activated T cell proliferation (IMP)

negative regulation of interleukin-10 production (IMP)

negative regulation of T cell apoptotic process (IMP)

negative regulation of T cell proliferation (IMP)

positive regulation of apoptotic process (IMP)

positive regulation of chronic inflammatory response (IMP)

positive regulation of interleukin-12 production (IMP)

positive regulation of T cell apoptotic process (ISO)

positive regulation of T cell tolerance induction (IMP)

positive regulation of type 2 immune response (IMP)

regulation of activated T cell proliferation (ISO)

response to lipopolysaccharide (IMP)

swimming behavior (IMP)

T cell proliferation (IMP)

tryptophan catabolic process (IEA)

tryptophan catabolic process to kynurenine (IBA,IDA,ISO)

Cellular Component

cytoplasm (IBA,IDA)

smooth muscle contractile fiber (IDA)

stereocilium bundle (IDA)

Molecular Function

amino acid binding (ISO)

dioxygenase activity (IEA)

heme binding (IEA)

indoleamine 2,3-dioxygenase activity (IBA,ISO)

metal ion binding (IEA)

oxidoreductase activity (IEA)

oxygen binding (ISO)

protein binding (IPI)

tryptophan 2,3-dioxygenase activity (IBA,IDA)

Molecular Pathway Annotations Click to see Annotation Detail View

kynurenine metabolic pathway (ISO)

sleeping sickness pathway (IEA)

tryptophan metabolic pathway (IEA,ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal autophagy (IAGP)

abnormal blood homeostasis (IAGP)

abnormal caput epididymis morphology (IAGP)

abnormal cytokine level (IAGP)

abnormal cytokine secretion (IAGP)

abnormal dendritic cell physiology (IAGP)

abnormal female reproductive system physiology (IAGP)

abnormal macrophage morphology (IAGP)

abnormal macrophage physiology (IAGP)

abnormal mitochondrial morphology (IAGP)

abnormal mitophagy (IAGP)

abnormal oxidative phosphorylation (IAGP)

abnormal physiological response to xenobiotic (IAGP)

abnormal pregnancy (IAGP)

abnormal protein level (IAGP)

abnormal renal glomerulus morphology (IAGP)

abnormal vasodilation (IAGP)

decreased heart rate (IAGP)

decreased leukocyte cell number (IAGP)

decreased mitochondrial number (IAGP)

decreased susceptibility to type IV hypersensitivity reaction (IAGP)

enlarged sperm head (IAGP)

epididymis inflammation (IAGP)

hairpin sperm flagellum (IAGP)

increased interferon-gamma secretion (IAGP)

increased interleukin-6 secretion (IAGP)

increased sperm number (IAGP)

increased systemic arterial blood pressure (IAGP)

increased tumor necrosis factor secretion (IAGP)

increased urine protein level (IAGP)

pinhead sperm (IAGP)

teratozoospermia (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Tolerogenic Plasmacytoid Dendritic Cells Control Paracoccidioides brasiliensis Infection by Inducting Regulatory T Cells in an IDO-Dependent Manner.	Araújo EF, etal., PLoS Pathog. 2016 Dec 19;12(12):e1006115. doi: 10.1371/journal.ppat.1006115. eCollection 2016 Dec.
2.	Aryl hydrocarbon receptor control of a disease tolerance defence pathway.	Bessede A, etal., Nature. 2014 Jul 10;511(7508):184-90. doi: 10.1038/nature13323.
3.	Tryptophan metabolism to kynurenine is a potential novel contributor to hypotension in human sepsis.	Changsirivathanathamrong D, etal., Crit Care Med. 2011 Dec;39(12):2678-83. doi: 10.1097/CCM.0b013e31822827f2.
4.	Tryptophan catabolism reflects disease activity in human tuberculosis.	Collins JM, etal., JCI Insight. 2020 May 21;5(10). pii: 137131. doi: 10.1172/jci.insight.137131.
5.	Comparative effects of oxygen on indoleamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase of the kynurenine pathway.	Dang Y, etal., Free Radic Biol Med. 2000 Feb 15;28(4):615-24.
6.	IL-22 and IDO1 affect immunity and tolerance to murine and human vaginal candidiasis.	De Luca A, etal., PLoS Pathog. 2013;9(7):e1003486. doi: 10.1371/journal.ppat.1003486. Epub 2013 Jul 11.
7.	LPS-conditioned dendritic cells confer endotoxin tolerance contingent on tryptophan catabolism.	Fallarino F, etal., Immunobiology. 2015 Feb;220(2):315-21. doi: 10.1016/j.imbio.2014.09.017. Epub 2014 Sep 28.
8.	Drug analog inhibition of indoleamine 2,3-dioxygenase (IDO) activity modifies pattern recognition receptor expression and proinflammatory cytokine responses early during influenza virus infection.	Fox JM, etal., J Leukoc Biol. 2014 Sep;96(3):447-52. doi: 10.1189/jlb.3AB0114-046RR. Epub 2014 May 5.
9.	Neopterin levels and Kyn/Trp ratios were significantly increased in dengue virus patients and subsequently decreased after recovery.	Geisler S, etal., Int J Infect Dis. 2020 Feb;91:162-168. doi: 10.1016/j.ijid.2019.12.005. Epub 2019 Dec 9.
10.	IDO1 depletion induces an anti-inflammatory response in macrophages in mice with chronic viral myocarditis.	Guo G, etal., Cell Cycle. 2019 Oct;18(20):2598-2613. doi: 10.1080/15384101.2019.1652471. Epub 2019 Aug 15.
11.	Blockade of indoleamine 2,3-dioxygenase reduces mortality from peritonitis and sepsis in mice by regulating functions of CD11b+ peritoneal cells.	Hoshi M, etal., Infect Immun. 2014 Nov;82(11):4487-95. doi: 10.1128/IAI.02113-14. Epub 2014 Aug 11.
12.	Induction and role of indoleamine 2,3 dioxygenase in mouse models of influenza a virus infection.	Huang L, etal., PLoS One. 2013 Jun 13;8(6):e66546. doi: 10.1371/journal.pone.0066546. Print 2013.
13.	Indoleamine 2,3-dioxygenase 1 deletion promotes Theiler's virus-induced seizures in C57BL/6J mice.	Juda MB, etal., Epilepsia. 2019 Apr;60(4):626-635. doi: 10.1111/epi.14675. Epub 2019 Feb 15.
14.	The kynurenine pathway and neurodegenerative disease.	Maddison DC and Giorgini F, Semin Cell Dev Biol. 2015 Apr;40:134-41. doi: 10.1016/j.semcdb.2015.03.002. Epub 2015 Mar 12.
15.	MGDs mouse GO annotations	MGD data from the GO Consortium
16.	MGD IEA	MGD IEA
17.	Epidermal Growth Factor Receptor-Responsive Indoleamine 2,3-Dioxygenase Confers Immune Homeostasis During Shigella flexneri Infection.	Mukherjee T, etal., J Infect Dis. 2019 May 5;219(11):1841-1851. doi: 10.1093/infdis/jiz009.
18.	Platelet-activating Factor Mediates Endotoxin Tolerance by Regulating Indoleamine 2,3-Dioxygenase-dependent Expression of the Suppressor of Cytokine Signaling 3.	Noh KT, etal., J Biol Chem. 2017 Feb 24;292(8):3290-3298. doi: 10.1074/jbc.M116.764464. Epub 2017 Jan 11.
19.	Enzymatic studies on tryptophan metabolism disorder in rats chronically exposed to carbon disulfide.	Okayama A, etal., Toxicol Appl Pharmacol. 1988 Jul;94(3):356-61.
20.	Indoleamine 2,3-dioxygenase 1 is a lung-specific innate immune defense mechanism that inhibits growth of Francisella tularensis tryptophan auxotrophs.	Peng K and Monack DM, Infect Immun. 2010 Jun;78(6):2723-33. doi: 10.1128/IAI.00008-10. Epub 2010 Apr 12.
21.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
22.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
23.	IDO1 Deficiency Does Not Affect Disease in Mouse Models of Systemic Juvenile Idiopathic Arthritis and Secondary Hemophagocytic Lymphohistiocytosis.	Put K, etal., PLoS One. 2016 Feb 25;11(2):e0150075. doi: 10.1371/journal.pone.0150075. eCollection 2016.
24.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
25.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
26.	Indolamine 2,3-dioxygenase expression by monocytes and dendritic cell populations in hepatitis C patients.	Schulz S, etal., Clin Exp Immunol. 2015 Jun;180(3):484-98. doi: 10.1111/cei.12586.
27.	Exaggerated IDO1 expression and activity in Langerhans cells from patients with atopic dermatitis upon viral stimulation: a potential predictive biomarker for high risk of Eczema herpeticum.	Staudacher A, etal., Allergy. 2015 Nov;70(11):1432-9. doi: 10.1111/all.12699. Epub 2015 Sep 2.
28.	The kynurenine pathway contributes to long-term neuropsychological changes in experimental pneumococcal meningitis.	Too LK, etal., Behav Brain Res. 2014 Aug 15;270:179-95. doi: 10.1016/j.bbr.2014.05.018. Epub 2014 May 17.
29.	Indoleamine 2,3-Dioxygenase Activity During Acute Toxoplasmosis and the Suppressed T Cell Proliferation in Mice.	Ufermann CM, etal., Front Cell Infect Microbiol. 2019 Jun 5;9:184. doi: 10.3389/fcimb.2019.00184. eCollection 2019.
30.	Indoleamine 2,3-Dioxygenase Activity in Chlamydia muridarum and Chlamydia pneumoniae Infected Mouse Lung Tissues.	Virok DP, etal., Front Cell Infect Microbiol. 2019 Jun 12;9:192. doi: 10.3389/fcimb.2019.00192. eCollection 2019.
31.	Role of indoleamine 2,3-dioxygenase in health and disease.	Yeung AW, etal., Clin Sci (Lond). 2015 Oct;129(7):601-72. doi: 10.1042/CS20140392.
32.	Indoleamine 2,3-dioxygenase 1 deficiency attenuates CCl4-induced fibrosis through Th17 cells down-regulation and tryptophan 2,3-dioxygenase compensation.	Zhong W, etal., Oncotarget. 2017 Jun 20;8(25):40486-40500. doi: 10.18632/oncotarget.17119.
33.	High expression of IDO1 and TGF-β1 during recurrence and post infection clearance with Chlamydia trachomatis, are independent of host IFN-γ response.	Ziklo N, etal., BMC Infect Dis. 2019 Mar 4;19(1):218. doi: 10.1186/s12879-019-3843-4.

Additional References at PubMed

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PMID:31694960	PMID:31746428	PMID:31760073	PMID:32024760	PMID:32027774	PMID:32127391	PMID:32210078	PMID:32226425	PMID:32325033	PMID:32546647	PMID:32752186	PMID:32771520
PMID:32973768	PMID:33021470	PMID:33095942	PMID:33272024	PMID:33363543	PMID:33414436	PMID:33552086	PMID:33591947	PMID:33622713	PMID:33649207	PMID:33831358	PMID:33899121
PMID:33941676	PMID:33960391	PMID:34025677	PMID:34087454	PMID:34093535	PMID:34130288	PMID:34242792	PMID:34290243	PMID:34394118	PMID:34407414	PMID:34576286	PMID:34614413
PMID:34680153	PMID:34716244	PMID:34735466	PMID:34788602	PMID:34867973	PMID:35154484	PMID:35398604	PMID:35563591	PMID:35704993	PMID:35711916	PMID:35715443	PMID:36163134
PMID:36227694	PMID:36343752	PMID:36422996	PMID:36439161	PMID:36675130	PMID:36706593	PMID:36733497	PMID:37155343	PMID:37485661	PMID:37794698

Genomics

Comparative Map Data

Ido1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	25,074,148 - 25,086,987 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	25,074,152 - 25,087,025 (-)	Ensembl		GRCm39 Ensembl
GRCm38	8	24,584,133 - 24,596,952 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	24,584,136 - 24,597,009 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	25,694,613 - 25,707,481 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	26,049,686 - 26,062,554 (-)	NCBI		MGSCv36	mm8
Celera	8	26,068,313 - 26,081,132 (-)	NCBI		Celera
Cytogenetic Map	8	A2	NCBI
cM Map	8	12.76	NCBI

IDO1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	39,913,891 - 39,928,790 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	39,902,275 - 39,928,790 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	39,771,410 - 39,786,309 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	39,890,485 - 39,905,107 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	39,890,484 - 39,905,102	NCBI
Celera	8	38,723,061 - 38,737,682 (+)	NCBI		Celera
Cytogenetic Map	8	p11.21	NCBI
HuRef	8	38,304,038 - 38,319,017 (+)	NCBI		HuRef
CHM1_1	8	39,817,930 - 39,832,909 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	40,190,729 - 40,205,625 (+)	NCBI		T2T-CHM13v2.0

Ido1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	16	67,430,654 - 67,442,726 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	67,430,578 - 67,442,730 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	72,707,823 - 72,719,592 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	76,112,135 - 76,124,005 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	71,361,330 - 71,373,199 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	72,216,326 - 72,228,098 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	72,216,326 - 72,228,098 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	71,866,330 - 71,878,339 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	71,866,340 - 71,878,373 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	71,866,604 - 71,878,638 (+)	NCBI
Celera	16	65,330,156 - 65,341,814 (+)	NCBI		Celera
Cytogenetic Map	16	q12.5	NCBI

Ido1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955536	2,943,611 - 2,955,829 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955536	2,944,770 - 2,955,829 (-)	NCBI	ChiLan1.0	ChiLan1.0

IDO1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	8	34,087,337 - 34,102,106 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	39,108,310 - 39,123,611 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	36,606,721 - 36,632,371 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	36,617,312 - 36,632,352 (+)	Ensembl	panpan1.1		panPan2

IDO1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	25,391,759 - 25,407,161 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	25,391,754 - 25,407,048 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	25,901,596 - 25,916,857 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	27,218,925 - 27,234,204 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	27,218,820 - 27,234,153 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	25,516,922 - 25,532,182 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	26,072,694 - 26,087,946 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	26,131,508 - 26,146,796 (-)	NCBI		UU_Cfam_GSD_1.0

Ido1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	48,593,856 - 48,608,521 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936843	657,979 - 672,700 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936843	658,058 - 672,662 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IDO1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	9,245,196 - 9,260,473 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	9,245,283 - 9,260,140 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	10,913,978 - 10,928,837 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IDO1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	37,930,910 - 37,950,790 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	37,930,562 - 37,946,505 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666052	3,981,103 - 3,996,711 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ido1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624780	3,685,069 - 3,697,474 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624780	3,684,941 - 3,697,506 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ido1
479 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	122
Count of miRNA genes:	59
Interacting mature miRNAs:	61
Transcripts:	ENSMUST00000033956, ENSMUST00000110667
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
11533914	Mts5_m	mammary tumor susceptibility 5 (mouse)					8	1	30447432	Mouse
4140978	Nilac5_m	nicotine induced locomotor activity 5 (mouse)			Not determined		8	1	31773288	Mouse
27226756	Femd2_m	femur midshaft diameter 2, 5 week (mouse)					8	4950000	35067154	Mouse
1301532	Scc8_m	colon tumor susceptibility 8 (mouse)			Not determined		8	7212499	35110107	Mouse
1300906	Ap8q_m	alcohol preference 8 QTL (mouse)			Not determined		8	7984189	41984342	Mouse
10412209	Cypr7_m	cytokine production 7 (mouse)			Not determined		8	8103201	42103372	Mouse
1301929	Eae24_m	susceptibility to experimental allergic encephalomyelitis 24 (mouse)			Not determined		8	8103201	42103372	Mouse
1301128	Sluc20_m	susceptibility to lung cancer 20 (mouse)			Not determined		8	8103201	42103372	Mouse
11532713	Sluc42_m	susceptibility to lung cancer 42 (mouse)					8	13447210	35321225	Mouse
1558870	Eae36_m	experimental allergic encephalomyelitis susceptibility 36 (mouse)			Not determined		8	14773160	71498244	Mouse
1301088	Alcw6_m	alcohol withdrawal 6 (mouse)			Not determined		8	15506572	49506729	Mouse
1300912	Daq19_m	directional asymmetry QTL 19 (mouse)			Not determined		8	15506572	49506729	Mouse
1301298	Pgia4_m	proteoglycan induced arthritis 4 (mouse)			Not determined		8	16569373	50569697	Mouse
4142199	Poats1_m	post-ovarectomy adrenal tumor susceptibility 1 (mouse)			Not determined			17082626	28849467	Mouse
1301550	Fembrs2_m	femur breaking strength 2 (mouse)			Not determined		8	18321097	52321225	Mouse
1301160	Eae14_m	susceptibility to experimental allergic encephalomyelitis 14 (mouse)			Not determined		8	19455018	53455150	Mouse
1300603	Cd8ts2_m	CD8 T cell subset 2 (mouse)			Not determined		8	19455018	53455150	Mouse

Markers in Region

M69109

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	8	24,584,251 - 24,584,379	UniSTS	GRCm38
MGSCv37	8	25,694,723 - 25,694,851	UniSTS	GRCm37
Celera	8	26,068,423 - 26,068,551	UniSTS
Cytogenetic Map	8	A2	UniSTS
Whitehead/MRC_RH	8	288.35	UniSTS

Ido

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	8	A2	UniSTS
cM Map	8		UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001293690	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_008324	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC114602	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK033783	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AV381637	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC049931	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466580	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M69109	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSMUST00000033956 ⟹ ENSMUSP00000033956

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	8	25,074,152 - 25,087,025 (-)	Ensembl
GRCm38.p6 Ensembl	8	24,584,136 - 24,597,009 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000110667 ⟹ ENSMUSP00000106295

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	8	25,074,152 - 25,085,682 (-)	Ensembl
GRCm38.p6 Ensembl	8	24,584,136 - 24,595,666 (-)	Ensembl

RefSeq Acc Id:

NM_001293690 ⟹ NP_001280619

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	8	25,074,148 - 25,085,682 (-)	NCBI
GRCm38	8	24,584,133 - 24,595,666 (-)	NCBI
Celera	8	26,068,305 - 26,081,075 (-)	NCBI

Sequence:

show sequence

GTCTTTGGGCACCAAGCCTGATATCCTTGCTACAAGTGTCCTGGCGCCTGCATCTTTGGGTGCC
CTGGCGTGCCTGGTTTTGAGGTTTTCGTGTATCCGGTCACGAATGTGGAACTGACCACCTCAGG
GTTTAGCGCTGCAGTTCTCAACCTTCTTAATGCTGAAACCTTTTCTAAAGTTCCTCATGTTGTG
ATGACCCCGGACGGTAAAATTATTTTCGTTGCTACGTCACAACTGTAATTTTGCTACTGTTTTG
AATTGTAATGTGGAGCTGCCCGACGCATACAGCCCCTGGGTCCTTGTGGCTAGAAATCTGCCTG
TGCTGATTGAGAACGGGCAGCTTCGAGAAGAAGTTGAAAAGCTGCCCACACTGAGCACGGACGG
ACTGAGAGGACACAGGTTACAGCGCCTGGCACACCTGGCCCTGGGGTACATCACCATGGCGTAT
GTGTGGAACCGAGGGGATGACGATGTTCGAAAGGTGCTGCCCCGCAATATTGCTGTTCCCTACT
GCGAGCTCTCAGAGAAGTTGGGCCTGCCTCCTATTCTGTCTTATGCAGACTGTGTCCTGGCAAA
CTGGAAGAAAAAGGACCCCAATGGGCCCATGACATACGAGAACATGGACATTCTGTTCTCATTT
CCTGGTGGGGACTGCGACAAGGGCTTCTTCCTCGTCTCTCTATTGGTGGAAATCGCAGCTTCTC
CTGCAATCAAAGCAATCCCCACTGTATCCAGTGCAGTAGAGCGTCAAGACCTGAAAGCATTGGA
AAAGGCACTGCACGACATAGCTACCAGTCTGGAGAAAGCCAAGGAAATTTTTAAGAGGATGCGT
GACTTTGTGGACCCAGACACGTTTTTCCACGTTCTCCGCATATATCTGTCTGGCTGGAAATGCA
GCTCCAAGCTGCCAGAAGGTCTGCTGTATGAGGGGGTCTGGGACACCCCAAAAATGTTTTCAGG
GGGCAGTGCAGGCCAGAGCAGCATCTTCCAGAGTCTTGATGTCCTTCTGGGAATAAAACACGAG
GCTGGCAAAGAATCTCCTGCAGAATTCCTCCAGGAAATGAGAGAGTACATGCCTCCAGCCCACC
GGAACTTCCTTTTCTTCTTAGAGTCAGCTCCCCCAGTCCGTGAGTTTGTCATTTCAAGACACAA
TGAAGACTTGACGAAAGCTTATAACGAGTGTGTGAATGGTCTGGTCTCTGTGAGAAAGTTCCAC
CTCGCAATAGTAGATACTTACATTATGAAACCTTCGAAGAAGAAGCCCACTGATGGCGACAAGT
CGGAAGAGCCCTCAAATGTGGAAAGCAGAGGGACTGGGGGTACGAATCCCATGACTTTCCTAAG
GAGTGTGAAAGATACAACCGAGAAAGCTCTTCTGAGTTGGCCTTAGTGTAGCAAGCTCCACTTC
TATCAGGGCACAGAAAACACCTTCATCCTGTCATAGCTCATTAAATCAGATCCACCAAGTAAGA
CTATAGAATAATTTGCCTGTTGTATATTATGTAGATTTCAAAAATCATCTGTGCATTCCCTGTA
GGAAAATAATCAAGCTGAACTATTTAATGATATTAAAATGATATAAGAAATAATATAAAATATA
TTTATGATTGAAATACAACAATGAGACCCAGTAAATAAAAGTTATTGTGAAGTTGACTA

hide sequence

RefSeq Acc Id:

NM_008324 ⟹ NP_032350

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	8	25,074,148 - 25,086,987 (-)	NCBI
GRCm38	8	24,584,133 - 24,596,952 (-)	NCBI
MGSCv37	8	25,694,613 - 25,707,481 (-)	RGD
Celera	8	26,068,305 - 26,081,075 (-)	NCBI
cM Map	8		ENTREZGENE

Sequence:

show sequence

GGAGTAGACAGCAATGGCACTCAGTAAAATATCTCCTACAGAAGGTTCTAGAAGGATCCTTGAA
GACCACCACATAGATGAAGATGTGGGCTTTGCTCTACCACATCCACTGGTGGAGCTGCCCGACG
CATACAGCCCCTGGGTCCTTGTGGCTAGAAATCTGCCTGTGCTGATTGAGAACGGGCAGCTTCG
AGAAGAAGTTGAAAAGCTGCCCACACTGAGCACGGACGGACTGAGAGGACACAGGTTACAGCGC
CTGGCACACCTGGCCCTGGGGTACATCACCATGGCGTATGTGTGGAACCGAGGGGATGACGATG
TTCGAAAGGTGCTGCCCCGCAATATTGCTGTTCCCTACTGCGAGCTCTCAGAGAAGTTGGGCCT
GCCTCCTATTCTGTCTTATGCAGACTGTGTCCTGGCAAACTGGAAGAAAAAGGACCCCAATGGG
CCCATGACATACGAGAACATGGACATTCTGTTCTCATTTCCTGGTGGGGACTGCGACAAGGGCT
TCTTCCTCGTCTCTCTATTGGTGGAAATCGCAGCTTCTCCTGCAATCAAAGCAATCCCCACTGT
ATCCAGTGCAGTAGAGCGTCAAGACCTGAAAGCATTGGAAAAGGCACTGCACGACATAGCTACC
AGTCTGGAGAAAGCCAAGGAAATTTTTAAGAGGATGCGTGACTTTGTGGACCCAGACACGTTTT
TCCACGTTCTCCGCATATATCTGTCTGGCTGGAAATGCAGCTCCAAGCTGCCAGAAGGTCTGCT
GTATGAGGGGGTCTGGGACACCCCAAAAATGTTTTCAGGGGGCAGTGCAGGCCAGAGCAGCATC
TTCCAGAGTCTTGATGTCCTTCTGGGAATAAAACACGAGGCTGGCAAAGAATCTCCTGCAGAAT
TCCTCCAGGAAATGAGAGAGTACATGCCTCCAGCCCACCGGAACTTCCTTTTCTTCTTAGAGTC
AGCTCCCCCAGTCCGTGAGTTTGTCATTTCAAGACACAATGAAGACTTGACGAAAGCTTATAAC
GAGTGTGTGAATGGTCTGGTCTCTGTGAGAAAGTTCCACCTCGCAATAGTAGATACTTACATTA
TGAAACCTTCGAAGAAGAAGCCCACTGATGGCGACAAGTCGGAAGAGCCCTCAAATGTGGAAAG
CAGAGGGACTGGGGGTACGAATCCCATGACTTTCCTAAGGAGTGTGAAAGATACAACCGAGAAA
GCTCTTCTGAGTTGGCCTTAGTGTAGCAAGCTCCACTTCTATCAGGGCACAGAAAACACCTTCA
TCCTGTCATAGCTCATTAAATCAGATCCACCAAGTAAGACTATAGAATAATTTGCCTGTTGTAT
ATTATGTAGATTTCAAAAATCATCTGTGCATTCCCTGTAGGAAAATAATCAAGCTGAACTATTT
AATGATATTAAAATGATATAAGAAATAATATAAAATATATTTATGATTGAAATACAACAATGAG
ACCCAGTAAATAAAAGTTATTGTGAAGTTGACTA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001280619	(Get FASTA)	NCBI Sequence Viewer
	NP_032350	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA37872	(Get FASTA)	NCBI Sequence Viewer
	AAH49931	(Get FASTA)	NCBI Sequence Viewer
	EDL32854	(Get FASTA)	NCBI Sequence Viewer
	EDL32855	(Get FASTA)	NCBI Sequence Viewer
	EDL32856	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000033956
	ENSMUSP00000106295
	ENSMUSP00000106295.2
GenBank Protein	P28776	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_032350 ⟸ NM_008324
- Peptide Label:	isoform 1
- UniProtKB:	P28776 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MALSKISPTEGSRRILEDHHIDEDVGFALPHPLVELPDAYSPWVLVARNLPVLIENGQLREEVE KLPTLSTDGLRGHRLQRLAHLALGYITMAYVWNRGDDDVRKVLPRNIAVPYCELSEKLGLPPIL SYADCVLANWKKKDPNGPMTYENMDILFSFPGGDCDKGFFLVSLLVEIAASPAIKAIPTVSSAV ERQDLKALEKALHDIATSLEKAKEIFKRMRDFVDPDTFFHVLRIYLSGWKCSSKLPEGLLYEGV WDTPKMFSGGSAGQSSIFQSLDVLLGIKHEAGKESPAEFLQEMREYMPPAHRNFLFFLESAPPV REFVISRHNEDLTKAYNECVNGLVSVRKFHLAIVDTYIMKPSKKKPTDGDKSEEPSNVESRGTG GTNPMTFLRSVKDTTEKALLSWP hide sequence

RefSeq Acc Id:	NP_001280619 ⟸ NM_001293690
- Peptide Label:	isoform 2
- UniProtKB:	D3YXV1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAYVWNRGDDDVRKVLPRNIAVPYCELSEKLGLPPILSYADCVLANWKKKDPNGPMTYENMDIL FSFPGGDCDKGFFLVSLLVEIAASPAIKAIPTVSSAVERQDLKALEKALHDIATSLEKAKEIFK RMRDFVDPDTFFHVLRIYLSGWKCSSKLPEGLLYEGVWDTPKMFSGGSAGQSSIFQSLDVLLGI KHEAGKESPAEFLQEMREYMPPAHRNFLFFLESAPPVREFVISRHNEDLTKAYNECVNGLVSVR KFHLAIVDTYIMKPSKKKPTDGDKSEEPSNVESRGTGGTNPMTFLRSVKDTTEKALLSWP hide sequence

RefSeq Acc Id:

ENSMUSP00000106295 ⟸ ENSMUST00000110667

RefSeq Acc Id:

ENSMUSP00000033956 ⟸ ENSMUST00000033956

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P28776-F1-model_v2	AlphaFold	P28776	1-407	view protein structure

Promoters

RGD ID:

8666727

Promoter ID:

EPDNEW_M11395

Type:

initiation region

Name:

Ido1_2

Description:

Mus musculus indoleamine 2,3-dioxygenase 1 , transcript variant1, mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_M11396

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	8	24,595,644 - 24,595,704	EPDNEW

RGD ID:

8666729

Promoter ID:

EPDNEW_M11396

Type:

multiple initiation site

Name:

Ido1_1

Description:

Mus musculus indoleamine 2,3-dioxygenase 1 , transcript variant1, mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_M11395

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	8	24,596,971 - 24,597,031	EPDNEW

RGD ID:

6843310

Promoter ID:

MM_KWN:53980

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

BoneMarrow_2Hour, Kidney, Lung

Transcripts:

ENSMUST00000110667

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	8	25,705,986 - 25,706,486 (-)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:96416	AgrOrtholog
Ensembl Genes	ENSMUSG00000031551	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000033956	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSMUST00000110667	ENTREZGENE
	ENSMUST00000110667.8	UniProtKB/TrEMBL
Gene3D-CATH	1.20.58.480	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Indolamine_dOase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Trp/Indoleamine_2_3_dOase-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:15930	UniProtKB/Swiss-Prot
MGD	MGI:96416	ENTREZGENE
NCBI Gene	15930	ENTREZGENE
PANTHER	INDOLEAMINE 2,3-DIOXYGENASE 1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR28657	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	IDO	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Ido1	PhenoGen
PROSITE	IDO_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IDO_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF140959	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	D3YXV1	ENTREZGENE, UniProtKB/TrEMBL
	I23O1_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

Mammalian Phenotype

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

Mammalian Phenotype