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Gene: IFNB1 (interferon beta 1) Homo sapiens
Symbol: IFNB1
Name: interferon beta 1
Description: Exhibits chloramphenicol O-acetyltransferase activity and cytokine activity. Involved in several processes, including cellular response to cytokine stimulus; negative regulation of T-helper 2 cell cytokine production; and positive regulation of macromolecule metabolic process. Predicted to localize to the extracellular space.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: fibroblast interferon; IFB; IFF; IFN-beta; IFNB; interferon beta; interferon, beta 1; interferon, beta 1, fibroblast; interferon-beta; MGC96956
Mus musculus (house mouse) : Ifnb1 (interferon beta 1, fibroblast)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ifnb1 (interferon beta 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ifnb1 (interferon beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IFNB1 (interferon beta 1)
Canis lupus familiaris (dog) : IFNB1 (interferon beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101968765 (interferon beta)
Sus scrofa (pig) : IFNB1 (interferon beta 1)
Chlorocebus sabaeus (green monkey) : IFNB1 (interferon beta 1)
Heterocephalus glaber (naked mole-rat) : Ifnb1 (interferon beta 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl921,077,104 - 21,077,942 (-)Ensembl
GRCh38921,077,104 - 21,077,942 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37921,077,104 - 21,077,943 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36921,067,104 - 21,067,943 (-)NCBINCBI36hg18NCBI36
Build 34921,067,103 - 21,067,943NCBI
Celera921,015,373 - 21,016,212 (-)NCBI
Cytogenetic Map9p21.3NCBI
HuRef921,040,313 - 21,041,152 (-)NCBIHuRef
CHM1_1921,076,893 - 21,077,751 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on IFNB1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736615
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.