Foxp3 (forkhead box P3) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Foxp3 (forkhead box P3) Chinchilla lanigera
Analyze
Symbol: Foxp3
Name: forkhead box P3
RGD ID: 8834519
Description: ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN B cell homeostasis (ortholog); CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation (ortholog); establishment of endothelial blood-brain barrier (ortholog); ASSOCIATED WITH Acute-On-Chronic Liver Failure (ortholog); adult T-cell leukemia (ortholog); Airway Remodeling (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: forkhead box protein P3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955543731,707 - 742,606 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955543731,707 - 742,606 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute-On-Chronic Liver Failure  (ISO)
adult T-cell leukemia  (ISO)
Airway Remodeling  (ISO)
allergic disease  (ISO)
anemia  (ISO)
Animal Toxoplasmosis  (ISO)
anogenital venereal wart  (ISO)
asthma  (ISO)
autistic disorder  (ISO)
bacterial pneumonia  (ISO)
Breast Neoplasms  (ISO)
bronchiolitis obliterans  (ISO)
cervical squamous cell carcinoma  (ISO)
chlamydia  (ISO)
Chronic Hepatitis B  (ISO)
Chronic Hepatitis C  (ISO)
colorectal cancer  (ISO)
congenital disorder of glycosylation type IIm  (ISO)
cutaneous leishmaniasis  (ISO)
dermatitis  (ISO)
diabetes mellitus  (ISO)
Dysbiosis  (ISO)
endometriosis  (ISO)
Endotoxemia  (ISO)
Epstein-Barr Virus Infections  (ISO)
Experimental Arthritis  (ISO)
Experimental Autoimmune Myocarditis  (ISO)
Experimental Autoimmune Neuritis  (ISO)
Experimental Colitis  (ISO)
Experimental Diabetes Mellitus  (ISO)
genetic disease  (ISO)
Graft vs Host Disease  (ISO)
hepatitis B  (ISO)
hepatitis C  (ISO)
hepatocellular carcinoma  (ISO)
Hydranencephaly with Renal Aplasia-Dysplasia  (ISO)
Hydrops Fetalis  (ISO)
hypertension  (ISO)
hypothyroidism  (ISO)
immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome  (ISO)
infectious mononucleosis  (ISO)
intrahepatic cholangiocarcinoma  (ISO)
Korean hemorrhagic fever  (ISO)
Lung Injury  (ISO)
malaria  (ISO)
multidrug-resistant tuberculosis  (ISO)
Neuralgia  (ISO)
neurodegeneration with brain iron accumulation 5  (ISO)
occupational dermatitis  (ISO)
papillomavirus infectious disease  (ISO)
pleural tuberculosis  (ISO)
polycystic ovary syndrome  (ISO)
primary biliary cholangitis  (ISO)
pulmonary tuberculosis  (ISO)
Recurrent Respiratory Papillomatosis  (ISO)
rheumatoid arthritis  (ISO)
Sepsis  (ISO)
spermatogenic failure 3  (ISO)
Spinal Cord Injuries  (ISO)
Squamous Intraepithelial Lesions of the Cervix  (ISO)
syndromic X-linked intellectual disability Lubs type  (ISO)
syphilis  (ISO)
Transplant Rejection  (ISO)
tropical spastic paraparesis  (ISO)
type 1 diabetes mellitus  (ISO)
vaccinia  (ISO)
Wound Infection  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
B cell homeostasis  (ISO)
CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation  (ISO)
establishment of endothelial blood-brain barrier  (ISO)
gene expression  (ISO)
myeloid cell homeostasis  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of chronic inflammatory response  (ISO)
negative regulation of CREB transcription factor activity  (ISO)
negative regulation of cytokine production  (ISO)
negative regulation of defense response to virus  (ISO)
negative regulation of DNA-binding transcription factor activity  (ISO)
negative regulation of gene expression  (ISO)
negative regulation of histone acetylation  (ISO)
negative regulation of histone deacetylation  (ISO)
negative regulation of immune response  (ISO)
negative regulation of inflammatory response  (ISO)
negative regulation of interferon-gamma production  (ISO)
negative regulation of interleukin-10 production  (ISO)
negative regulation of interleukin-17 production  (ISO)
negative regulation of interleukin-2 production  (ISO)
negative regulation of interleukin-4 production  (ISO)
negative regulation of interleukin-5 production  (ISO)
negative regulation of interleukin-6 production  (ISO)
negative regulation of isotype switching to IgE isotypes  (ISO)
negative regulation of lymphocyte proliferation  (ISO)
negative regulation of NF-kappaB transcription factor activity  (ISO)
negative regulation of T cell cytokine production  (ISO)
negative regulation of T cell proliferation  (ISO)
negative regulation of T-helper 17 cell differentiation  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
negative regulation of transcription, DNA-templated  (ISO)
negative regulation of tumor necrosis factor production  (ISO)
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of histone acetylation  (ISO)
positive regulation of immature T cell proliferation in thymus  (ISO)
positive regulation of interleukin-4 production  (ISO)
positive regulation of peripheral T cell tolerance induction  (ISO)
positive regulation of regulatory T cell differentiation  (ISO)
positive regulation of T cell anergy  (ISO)
positive regulation of T cell tolerance induction  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of transcription, DNA-templated  (ISO)
positive regulation of transforming growth factor beta1 production  (ISO)
regulation of immunoglobulin production  (ISO)
regulation of isotype switching to IgG isotypes  (ISO)
regulation of T cell anergy  (ISO)
regulation of transcription by RNA polymerase II  (ISO)
response to lipopolysaccharide  (ISO)
response to radiation  (ISO)
response to rapamycin  (ISO)
response to virus  (ISO)
T cell activation  (ISO)
T cell mediated immunity  (ISO)
T cell receptor signaling pathway  (ISO)
tolerance induction  (ISO)
tolerance induction to self antigen  (ISO)

Cellular Component
cytoplasm  (ISO)
nucleoplasm  (ISO)
nucleus  (ISO)

References


Genomics

Comparative Map Data
Foxp3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955543731,707 - 742,606 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955543731,707 - 742,606 (-)NCBIChiLan1.0ChiLan1.0
FOXP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX49,250,438 - 49,270,477 (-)EnsemblGRCh38hg38GRCh38
GRCh38X49,250,436 - 49,264,932 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X49,106,899 - 49,121,172 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X48,994,354 - 49,008,232 (-)NCBINCBI36hg18NCBI36
Build 34X48,863,780 - 48,877,659NCBI
CeleraX52,543,105 - 52,557,472 (+)NCBI
Cytogenetic MapXp11.23NCBI
HuRefX46,763,332 - 46,777,541 (-)NCBIHuRef
CHM1_1X49,139,199 - 49,153,588 (-)NCBICHM1_1
Foxp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X7,445,915 - 7,461,482 (+)NCBIGRCm39mm39
GRCm39 EnsemblX7,439,883 - 7,461,484 (+)Ensembl
GRCm38X7,579,676 - 7,595,243 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX7,573,644 - 7,595,245 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X7,156,819 - 7,172,360 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X6,736,652 - 6,752,193 (+)NCBImm8
CeleraX3,876,537 - 3,892,077 (-)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX3.41NCBI
Foxp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X14,908,494 - 14,924,994 (-)NCBI
Rnor_6.0 EnsemblX15,753,175 - 15,768,522 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X15,753,175 - 15,768,648 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X16,544,710 - 16,565,562 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X26,950,006 - 26,965,329 (-)NCBIRGSC3.4rn4RGSC3.4
CeleraX14,991,861 - 15,007,179 (-)NCBICelera
Cytogenetic MapXq12NCBI
FOXP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X49,402,652 - 49,417,029 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX49,402,652 - 49,417,029 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X41,550,462 - 41,567,492 (-)NCBIMhudiblu_PPA_v0panPan3
FOXP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X42,331,229 - 42,362,841 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX42,344,108 - 42,350,758 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX16,722,772 - 16,729,421 (-)NCBI
ROS_Cfam_1.0X42,484,818 - 42,504,672 (-)NCBI
UMICH_Zoey_3.1X42,469,693 - 42,476,343 (-)NCBI
UNSW_CanFamBas_1.0X42,457,152 - 42,463,801 (-)NCBI
UU_Cfam_GSD_1.0X42,552,106 - 42,558,755 (-)NCBI
Foxp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X34,877,987 - 34,897,169 (-)NCBI
SpeTri2.0NW_0049367211,118,376 - 1,125,282 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FOXP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX43,303,782 - 43,328,735 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X43,303,777 - 43,328,164 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X48,151,901 - 48,175,580 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FOXP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X46,349,890 - 46,365,133 (-)NCBI
Vero_WHO_p1.0NW_02366607611,912,136 - 11,927,083 (-)NCBI
Foxp3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624893995,145 - 1,008,492 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000007470   ⟹   ENSCLAP00000007353
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955543731,707 - 742,606 (-)Ensembl
RefSeq Acc Id: XM_013508158   ⟹   XP_013363612
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955543731,707 - 742,606 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013363612 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013363612   ⟸   XM_013508158
- Sequence:
RefSeq Acc Id: ENSCLAP00000007353   ⟸   ENSCLAT00000007470


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000005172 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000007353 ENTREZGENE
Ensembl Transcript ENSCLAT00000007470 ENTREZGENE
NCBI Gene Foxp3 ENTREZGENE