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Gene: Pdcd1 (programmed cell death 1) Mus musculus
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Symbol: Pdcd1
Name: programmed cell death 1
Description: Involved in negative regulation of immune response; negative regulation of tolerance induction; and regulation of apoptotic process. Localizes to the external side of plasma membrane. Used to study dilated cardiomyopathy and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in lupus nephritis; multiple sclerosis; and systemic lupus erythematosus. Is expressed in retina. Orthologous to human PDCD1 (programmed cell death 1); PARTICIPATES IN T cell receptor signaling pathway; INTERACTS WITH (+)-dexrazoxane; 17alpha-ethynylestradiol; amodiaquine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ly101; mPD-1; PD-1; Pdc1; programmed cell death protein 1
Orthologs:
Homo sapiens (human) : PDCD1 (programmed cell death 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pdcd1 (programmed cell death 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdcd1 (programmed cell death 1)
Canis lupus familiaris (dog) : PDCD1 (programmed cell death 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdcd1 (programmed cell death 1)
Sus scrofa (pig) : PDCD1 (programmed cell death 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl194,038,305 - 94,052,553 (-)Ensembl
GRCm38194,038,305 - 94,052,553 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37195,934,882 - 95,949,130 (-)NCBIGRCm37mm9NCBIm37
MGSCv36195,868,711 - 95,882,959 (-)NCBImm8
Celera196,903,284 - 96,917,529 (-)NCBICelera
Cytogenetic Map1 DNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pdcd1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1323232
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.