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Gene: Keap1 (kelch like ECH associated protein 1) Chinchilla lanigera

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Symbol:

Keap1

Name:

kelch like ECH associated protein 1

RGD ID:

9046568

Description:

ENCODES a protein that exhibits disordered domain specific binding (ortholog); identical protein binding (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN cellular response to carbohydrate stimulus (ortholog); cellular response to interleukin-4 (ortholog); cellular response to oxidative stress (ortholog); PARTICIPATES IN nuclear factor, erythroid 2 like 2 signaling pathway; ASSOCIATED WITH Alcoholic Liver Diseases (ortholog); amyotrophic lateral sclerosis (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN actin filament (ortholog); adherens junction (ortholog); centriolar satellite (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

kelch-like ECH-associated protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955495	1,704,695 - 1,711,290 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955495	1,704,695 - 1,711,339 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alcoholic Liver Diseases (ISO)

amyotrophic lateral sclerosis (ISO)

Chemical and Drug Induced Liver Injury (ISO)

Chronic Hepatitis B (ISO)

Diabetic Nephropathies (ISO)

diabetic retinopathy (ISO)

Disease Progression (ISO)

end stage renal disease (ISO)

Endotoxemia (ISO)

extrahepatic cholestasis (ISO)

familial hypercholesterolemia (ISO)

gallbladder cancer (ISO)

Gallbladder Neoplasms (ISO)

gastrointestinal system disease (ISO)

Hepatic Insufficiency (ISO)

hepatitis (ISO)

Hepatomegaly (ISO)

idiopathic interstitial pneumonia (ISO)

immunodeficiency 35 (ISO)

keratosis (ISO)

lung non-small cell carcinoma (ISO)

primary biliary cholangitis (ISO)

Prostatic Neoplasms (ISO)

pulmonary emphysema (ISO)

renal cell carcinoma (ISO)

Reperfusion Injury (ISO)

Sepsis (ISO)

steatotic liver disease (ISO)

transient cerebral ischemia (ISO)

ureteral obstruction (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to carbohydrate stimulus (ISO)

cellular response to interleukin-4 (ISO)

cellular response to oxidative stress (ISO)

in utero embryonic development (ISO)

negative regulation of gene expression (ISO)

negative regulation of response to oxidative stress (ISO)

negative regulation of transcription by RNA polymerase II (ISO)

proteasome-mediated ubiquitin-dependent protein catabolic process (ISO)

protein ubiquitination (ISO)

regulation of autophagy (ISO)

regulation of DNA-templated transcription (ISO)

regulation of epidermal cell differentiation (ISO)

response to immobilization stress (ISO)

response to metal ion (ISO)

response to thyroid hormone (ISO)

selenium compound metabolic process (ISO)

ubiquitin-dependent protein catabolic process (ISO)

Cellular Component

actin filament (ISO)

adherens junction (ISO)

centriolar satellite (ISO)

Cul3-RING ubiquitin ligase complex (ISO)

cytoplasm (ISO)

cytosol (ISO)

endoplasmic reticulum (ISO)

focal adhesion (ISO)

inclusion body (ISO)

midbody (ISO)

nucleoplasm (ISO)

protein-containing complex (ISO)

Molecular Function

disordered domain specific binding (ISO)

identical protein binding (ISO)

protein binding (ISO)

RNA polymerase II-specific DNA-binding transcription factor binding (ISO)

transcription regulator inhibitor activity (ISO)

ubiquitin-like ligase-substrate adaptor activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

nuclear factor, erythroid 2 like 2 signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Keap1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955495	1,704,695 - 1,711,290 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955495	1,704,695 - 1,711,339 (-)	NCBI	ChiLan1.0	ChiLan1.0

KEAP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	10,486,125 - 10,503,356 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	10,486,125 - 10,503,558 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	10,596,801 - 10,614,032 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	10,457,796 - 10,475,054 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	19	10,491,509 - 10,508,764 (-)	NCBI		Celera
Cytogenetic Map	19	p13.2	NCBI
HuRef	19	10,176,101 - 10,192,927 (-)	NCBI		HuRef
CHM1_1	19	10,597,575 - 10,614,823 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	10,612,569 - 10,629,791 (-)	NCBI		T2T-CHM13v2.0

Keap1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	21,141,026 - 21,150,628 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	21,141,026 - 21,150,657 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	21,229,730 - 21,239,332 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	21,229,730 - 21,239,361 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	21,034,174 - 21,043,776 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	20,980,469 - 20,989,215 (-)	NCBI		MGSCv36	mm8
Celera	9	18,498,845 - 18,508,447 (-)	NCBI		Celera
Cytogenetic Map	9	A3	NCBI
cM Map	9	7.74	NCBI

Keap1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	28,044,555 - 28,054,042 (-)	NCBI		GRCr8
mRatBN7.2	8	19,768,375 - 19,777,862 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	19,768,375 - 19,777,862 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	23,787,814 - 23,797,272 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	22,085,659 - 22,095,117 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	19,998,059 - 20,007,547 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	22,250,518 - 22,259,868 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	22,250,518 - 22,259,779 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	22,305,765 - 22,315,026 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	20,259,178 - 20,266,351 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	20,259,177 - 20,266,352 (-)	NCBI
Celera	8	21,161,976 - 21,171,435 (-)	NCBI		Celera
Cytogenetic Map	8	q13	NCBI

KEAP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	15,404,143 - 15,421,611 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	14,402,746 - 14,420,092 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	10,037,544 - 10,055,091 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	10,701,298 - 10,717,664 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	10,701,303 - 10,717,604 (-)	Ensembl	panpan1.1		panPan2

KEAP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	50,651,070 - 50,661,178 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	50,650,711 - 50,658,496 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	50,523,052 - 50,533,206 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	51,174,558 - 51,182,077 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	51,164,570 - 51,185,490 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	50,380,711 - 50,390,863 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	50,808,833 - 50,818,993 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	51,049,891 - 51,060,051 (+)	NCBI		UU_Cfam_GSD_1.0

Keap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	209,560,465 - 209,569,647 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936659	782,340 - 793,688 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936659	785,059 - 793,775 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KEAP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	69,276,336 - 69,294,382 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	69,280,940 - 69,290,267 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	69,634,153 - 69,643,610 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KEAP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	9,515,789 - 9,526,699 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	9,515,416 - 9,522,797 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666074	10,471,467 - 10,484,386 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Keap1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	2,580,861 - 2,595,275 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624828	2,580,812 - 2,595,023 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013505131	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01061712	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBBH01001242	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDK01022727	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000016152 ⟹ ENSCLAP00000015988

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955495	1,704,695 - 1,711,290 (-)	Ensembl

RefSeq Acc Id:

XM_013505131 ⟹ XP_013360585

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955495	1,704,695 - 1,711,339 (-)	NCBI

Sequence:

show sequence

GGAACCTCCTGGCCGCGGCCCGCTGCGCCCTTCCCGCCCTCTCCCCGCCTCCTCCCCGCGCGTC
CCCCACCCGACGGCGCCACCTCGCCGGCCGCGCCGCCGCTTGCAGCCCAGGTCCCCCGACGGCG
GCAGCGGCGCCCCAGGGTCCCGGACGCCGAAGGCTGCCCAGGATCCGCCAGGCCCCGGCCGCGG
CCTCGGGCTTCCGGGAAGCGCGGCGCGCGCCTCCAGCCGCCCCAGCGCCCCGGGCCCGCCAGCG
CGCGGGACGCGGACGCAGCAGCGCCGGGCCGAGGCCTCTGACTGCCACTCGTGCTCTTGCTCCT
TGCCACCCGGAACCCCATGCAGCCGGAACCCAGGCCTAGCAGGGCGGGGGCCCGCGGCCGATTC
GTGCCCCTGCAGTCCAAGTGCCCCGAGGGGGCCGGGGACACGGTGATGTACGCGTCCACCGAAT
GCAAGGCCGAGGTGACCCCGTCCCAGGACGGCAACCGCACTTTCAGCTACACGCTGGAGGACCA
CACGAAGCAGGCCTTCGGCATCATGAACGAACTTCGGCTCAGCCAGCAGCTGTGCGATGTCACC
CTGCAGGTGAAGTATGAGGACATCCCCACGGCGCAGTTCATGGCGCACAAGGTGGTGCTGGCCT
CGTCCAGCCCCGTGTTCAAGGCCATGTTCACCAACGGGCTGCGGGAGCAGGGCATGGAGGTGGT
GTCCATCGAGGGCATCCACCCAATGGTCATGGAGCGGCTCATCGAGTTCGCCTACACCGCGTCC
ATCTCCATGGGCGAGAAGTGCGTGCTGCACGTCATGAACGGCGCCGTCATGTACCAGATCGACA
GCGTCGTGCGCGCCTGCAGCGACTTCCTGGTGGAGCAGCTCGACCCTAGCAATGCCATCGGCAT
CGCCAACTTCGCCGAGCAGATCGGCTGTGCCGAGCTGCACCAGCGGGCCCGCGAGTACATCTAC
ATGCACTTCGGGGAGGTGGCCAAGCAGGAGGAGTTCTTCAACCTGTCGCACTGCCAGCTAGCGA
CGCTGATCAGCCGGGACGACCTGAACGTGCGCTGCGAATCCGAGGTGTTCCACGCGTGCATCAA
CTGGGTCAAGTACGACTGCGAGCAGCGGCGCTTCTACGTGCAGGCGCTGCTGCGCGCCGTGCGC
TGCCACGCGCTCACGCCGCACTTCCTGCAGATGCAGCTGCAGAAGTGCGAGATCCTGCAGAGCG
ACTCGCGCTGCAAGGACTACCTGGTGCAGATCTTCCAGGAGCTCACGCTGCACAAGCCCACGCC
CGCCATGCCCTGCCGCGCGCCCAAGGTGGGCCGCCTCATCTACACGGCCGGCGGCTACTTCCGC
CAGTCGCTCAGCTACCTGGAGGCCTACAACCCGAGCGACGGCAGCTGGCTGCGCCTGGCCGACC
TGCAGGTGCCCCGCAGCGGGCTGGCGGGCTGCGTGGTGGGCGGGCTGCTCTACGCCGTGGGCGG
CCGCAACAACTCCCCGGAAGGCAACACCGACTCCAACGCCCTGGACTGCTACAACCCCATGACC
AATCAGTGGTCGCCCTGCGCCCCGATGAGCGTGCCCCGCAACCGCATCGGCGTGGGTGTCATCG
ATGGCCACATCTACGCCGTGGGGGGCTCGCACGGCTGCATCCACCACAACAGCGTGGAGAGGTA
TGAGCCCGAGCGGGACGAGTGGCACTTGGTGTCCCCGATGCTGACCCGGAGGATCGGTGTGGGC
GTGGCTGTCCTCAACCGCCTGCTCTACGCGGTCGGGGGCTTCGACGGGACGAGCCGCCTCAACT
CAGCGGAGTGCTACTACCCGGAGCACAACGAGTGGCGCCTGATCGCCCCCATGAACAGCATCCG
CAGCGGGGCAGGAGTCTGCGTACTGCACAACTGCATCTATGCTGCGGGCGGCTACGACGGTCAG
GACCAGCTCAACAGCGTGGAGCGCTACGACGTGGAGACCGAGACCTGGACGTTTGTGGCCTCCA
TGAAGCACCGGCGGAGCGCCCTGGGGATTACCGTGCACCAGGGGAGAATCTACGTCCTGGGAGG
TTATGACGGTCACACGTTCCTGGACAGTGTGGAATGCTACGACCCAGACACAGACACCTGGAGT
GAGGTGACCCGAATGACTTCCGGCCGCAGCGGGGTGGGCGTTGCTGTCACCATGGAGCCCTGCC
GGAAGCAGATCGACCAACGGAACTGTACCTGTTGAAGCACTTATGCTTCTTGGGCAAAAAAAAA
AGAGAGAGACGGTCTGACCCACAGCATTGTTTCCATACATAAAACAGGGACAAAAAAAGTGACA
GCAGATCTCGTCCTCCAGGGGGGGCCGGGCCACCTCCATGTGCAGGAGATAACCAGAAAGAAGA
GAGACCAGAGCAGGAAGCCCCAAGCCCCTCCGAGCCGCCCAGGAGTGTCCACAGCGTGCCCTGG
GGGGGCGGGGGGGGCGGGCGGAGAAGGTCCCCTTCCCTGCTGGGGACTGGGCCACGGCAGCCGC
CGCCCCCTCAGGGTGCGAGCAGGTGCCGCCCGAGGCTGCTTCTCCAGTCAGCGCCCACAGACTG
AGGCAGGGGCCGGGTGAGGCCTCGGGCTGAGGCCCCTCAGGAAACATGGTCCCCAGGGCTGGGT
CCCTCCAGAAAAGCCGCAGTGACCGTGGGGACAGTTGCTCTGTTGATAAATAACCCTGTAAGTT
TCCAGTGAAAATAAAGAACAGACTAACACTGTCTTCTACCCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_013360585	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000015988
	ENSCLAP00000015988.1

RefSeq Acc Id:

XP_013360585 ⟸ XM_013505131

- UniProtKB:

A0A8C2YQJ9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MQPEPRPSRAGARGRFVPLQSKCPEGAGDTVMYASTECKAEVTPSQDGNRTFSYTLEDHTKQAF
GIMNELRLSQQLCDVTLQVKYEDIPTAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGI
HPMVMERLIEFAYTASISMGEKCVLHVMNGAVMYQIDSVVRACSDFLVEQLDPSNAIGIANFAE
QIGCAELHQRAREYIYMHFGEVAKQEEFFNLSHCQLATLISRDDLNVRCESEVFHACINWVKYD
CEQRRFYVQALLRAVRCHALTPHFLQMQLQKCEILQSDSRCKDYLVQIFQELTLHKPTPAMPCR
APKVGRLIYTAGGYFRQSLSYLEAYNPSDGSWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSP
EGNTDSNALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERD
EWHLVSPMLTRRIGVGVAVLNRLLYAVGGFDGTSRLNSAECYYPEHNEWRLIAPMNSIRSGAGV
CVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVASMKHRRSALGITVHQGRIYVLGGYDGHT
FLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVTMEPCRKQIDQRNCTC

hide sequence

Ensembl Acc Id:

ENSCLAP00000015988 ⟸ ENSCLAT00000016152

Protein Domains

BTB

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000011003	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000016152	ENTREZGENE
	ENSCLAT00000016152.1	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.420	UniProtKB/TrEMBL
	2.120.10.80	UniProtKB/TrEMBL
	Potassium Channel Kv1.1, Chain A	UniProtKB/TrEMBL
InterPro	BACK	UniProtKB/TrEMBL
	BTB-kelch_protein	UniProtKB/TrEMBL
	BTB/POZ_dom	UniProtKB/TrEMBL
	KEAP1	UniProtKB/TrEMBL
	KEAP1_BACK	UniProtKB/TrEMBL
	Kelch-typ_b-propeller	UniProtKB/TrEMBL
	Kelch_1	UniProtKB/TrEMBL
	SKP1/BTB/POZ_sf	UniProtKB/TrEMBL
NCBI Gene	Keap1	ENTREZGENE
PANTHER	KELCH PROTEIN	UniProtKB/TrEMBL
	KELCH-LIKE PROTEIN 28	UniProtKB/TrEMBL
Pfam	BACK	UniProtKB/TrEMBL
	BTB	UniProtKB/TrEMBL
	Kelch_1	UniProtKB/TrEMBL
PIRSF	Kelch-like_protein_gigaxonin	UniProtKB/TrEMBL
PROSITE	BTB	UniProtKB/TrEMBL
SMART	BACK	UniProtKB/TrEMBL
	BTB	UniProtKB/TrEMBL
	Kelch	UniProtKB/TrEMBL
Superfamily-SCOP	SSF117281	UniProtKB/TrEMBL
	SSF54695	UniProtKB/TrEMBL
UniProt	A0A8C2YQJ9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-16	Keap1	kelch like ECH associated protein 1		kelch-like ECH-associated protein 1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations