Lepr Mouse (1->4)-beta-D-glucan multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of LEPR mRNA CTD PMID:36331819 Lepr Mouse (N(omega)-L-arginino)succinic acid affects abundance EXP 6480464 LEPR affects the abundance of Argininosuccinic Acid CTD PMID:20567778 Lepr Mouse (R)-carnitine affects abundance EXP 6480464 LEPR affects the abundance of Carnitine CTD PMID:20567778 Lepr Mouse (R)-pantothenic acid affects abundance EXP 6480464 LEPR affects the abundance of Pantothenic Acid CTD PMID:20567778 Lepr Mouse (S)-nicotine increases expression ISO Lepr (Rattus norvegicus) 6480464 Nicotine results in increased expression of LEPR mRNA CTD PMID:22265867 Lepr Mouse (S)-nicotine decreases expression ISO Lepr (Rattus norvegicus) 6480464 Nicotine results in decreased expression of LEPR mRNA CTD PMID:29155039 Lepr Mouse 1,2-dichloroethane increases expression EXP 6480464 ethylene dichloride results in increased expression of LEPR mRNA CTD PMID:28960355 Lepr Mouse 1-methylnicotinamide affects abundance EXP 6480464 LEPR affects the abundance of N(1)-methylnicotinamide CTD PMID:20567778 Lepr Mouse 17alpha-ethynylestradiol multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LEPR mRNA and ESR1 gene mutant form inhibits the reaction [Ethinyl Estradiol results in increased expression of LEPR mRNA] CTD PMID:17942748 and PMID:29112739 Lepr Mouse 17alpha-ethynylestradiol affects expression ISO Lepr (Rattus norvegicus) 6480464 Ethinyl Estradiol affects the expression of LEPR mRNA CTD PMID:26865667 Lepr Mouse 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of LEPR mRNA CTD PMID:17942748 and PMID:29112739 Lepr Mouse 17alpha-ethynylestradiol decreases expression ISO Lepr (Rattus norvegicus) 6480464 Ethinyl Estradiol results in decreased expression of LEPR mRNA CTD PMID:17351261 Lepr Mouse 17beta-estradiol affects abundance ISO Lepr (Rattus norvegicus) 6480464 LEPR protein affects the abundance of Estradiol CTD PMID:15093691 Lepr Mouse 17beta-estradiol affects expression ISO Lepr (Rattus norvegicus) 6480464 Estradiol affects the expression of LEPR mRNA CTD PMID:32145629 Lepr Mouse 17beta-estradiol affects expression ISO Lepr (Rattus norvegicus) 1581837 17beta-estradiol decreases Lepr protein expression in adipose tissue at 7 weeks and increases it at 22 weeks RGD Lepr Mouse 17beta-estradiol multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of LEPR mRNA and [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in decreased expression of LEPR mRNA CTD PMID:26496021 and PMID:32741896 Lepr Mouse 17beta-estradiol decreases expression ISO LEPR (Homo sapiens) 6480464 Estradiol results in decreased expression of LEPR mRNA CTD PMID:19167446 Lepr Mouse 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of LEPR mRNA CTD PMID:14664709 Lepr Mouse 17beta-estradiol 3-benzoate multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in decreased expression of LEPR mRNA CTD PMID:32741896 Lepr Mouse 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions EXP 6480464 [2 more ... CTD PMID:24978599 and PMID:25510870 Lepr Mouse 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:29112739 Lepr Mouse 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions EXP 6480464 ESR1 gene mutant form inhibits the reaction [2 more ... CTD PMID:29112739 Lepr Mouse 2,2',5,5'-tetrachlorobiphenyl multiple interactions EXP 6480464 [2 more ... CTD PMID:25510870 Lepr Mouse 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO LEPR (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of LEPR mRNA CTD PMID:20106945 Lepr Mouse 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Lepr (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of LEPR mRNA CTD PMID:34747641 Lepr Mouse 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of LEPR mRNA CTD PMID:26290441 and PMID:33956508 Lepr Mouse 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of LEPR mRNA CTD PMID:26377647 and PMID:28922406 Lepr Mouse 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Lepr (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of LEPR mRNA CTD PMID:20959002 and PMID:21724226 Lepr Mouse 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO LEPR (Homo sapiens) 6480464 Tetrachlorodibenzodioxin affects the expression of LEPR mRNA CTD PMID:22298810 Lepr Mouse 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Lepr (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin affects the expression of LEPR mRNA CTD PMID:15977195 and PMID:22298810 Lepr Mouse 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LEPR mRNA CTD PMID:17942748 Lepr Mouse 2,4-dinitrotoluene affects expression ISO Lepr (Rattus norvegicus) 6480464 2 and 4-dinitrotoluene affects the expression of LEPR mRNA CTD PMID:21346803 Lepr Mouse 2,6-dinitrotoluene affects expression ISO Lepr (Rattus norvegicus) 6480464 2 and 6-dinitrotoluene affects the expression of LEPR mRNA CTD PMID:21346803 Lepr Mouse 2-amino-2-deoxy-D-galactopyranose increases response to substance EXP 6480464 LEPR gene mutant form results in increased susceptibility to Galactosamine CTD PMID:19913045 Lepr Mouse 2-amino-2-deoxy-D-galactopyranose multiple interactions EXP 6480464 [LEPR gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of IL12B mRNA more ... CTD PMID:19913045 Lepr Mouse 2-amino-2-deoxy-D-glucopyranose multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [LEPR protein affects the susceptibility to Glucosamine] which affects the expression of ALB protein CTD PMID:33345901 Lepr Mouse 2-amino-2-deoxy-D-glucopyranose affects response to substance ISO Lepr (Rattus norvegicus) 6480464 LEPR protein affects the susceptibility to Glucosamine CTD PMID:33345901 Lepr Mouse 2-hydroxy-4-methylvaleric acid affects abundance EXP 6480464 LEPR affects the abundance of alpha-hydroxyisocaproic acid CTD PMID:20567778 Lepr Mouse 2-hydroxyisobutyric acid affects abundance EXP 6480464 LEPR affects the abundance of 2-hydroxyisobutyric acid CTD PMID:20567778 Lepr Mouse 2-hydroxypropanoic acid affects abundance EXP 6480464 LEPR affects the abundance of Lactic Acid CTD PMID:20567778 Lepr Mouse 2-methyl-4-chlorophenoxybutyric acid multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [2-amino-3-chloro-1 and 4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in decreased expression of LEPR mRNA CTD PMID:29321614 Lepr Mouse 2-oxoadipic acid affects abundance EXP 6480464 LEPR affects the abundance of alpha-ketoadipic acid CTD PMID:20567778 Lepr Mouse 3-methyl-2-oxobutanoic acid affects abundance EXP 6480464 LEPR affects the abundance of alpha-ketoisovalerate CTD PMID:20567778 Lepr Mouse 3-methyl-2-oxovaleric acid affects abundance EXP 6480464 LEPR affects the abundance of alpha-keto-beta-methylvaleric acid CTD PMID:20567778 Lepr Mouse 4,4'-diaminodiphenylmethane affects expression EXP 6480464 4 and 4'-diaminodiphenylmethane affects the expression of LEPR mRNA CTD PMID:18648102 Lepr Mouse 4,4'-sulfonyldiphenol increases expression EXP 6480464 bisphenol S results in increased expression of LEPR mRNA CTD PMID:30951980 Lepr Mouse 4-hydroxy-TEMPO multiple interactions EXP 6480464 tempol inhibits the reaction [LEPR gene mutant form results in decreased susceptibility to Acetylcholine] CTD PMID:19478208 Lepr Mouse 4-phenylbutyric acid multiple interactions EXP 6480464 4-phenylbutyric acid affects the reaction [LEPR gene mutant form affects the splicing of XBP1 mRNA] more ... CTD PMID:23274897 Lepr Mouse 5-aza-2'-deoxycytidine decreases expression ISO LEPR (Homo sapiens) 6480464 Decitabine results in decreased expression of LEPR CTD PMID:22560341 Lepr Mouse 6-propyl-2-thiouracil affects expression ISO Lepr (Rattus norvegicus) 6480464 Propylthiouracil affects the expression of LEPR mRNA CTD PMID:24780913 Lepr Mouse 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions EXP 6480464 swietenine inhibits the reaction [LEPR gene mutant form results in increased abundance of Uric Acid] CTD PMID:36066211 Lepr Mouse 7,9-dihydro-1H-purine-2,6,8(3H)-trione increases abundance EXP 6480464 LEPR gene mutant form results in increased abundance of Uric Acid CTD PMID:36066211 Lepr Mouse 8-Br-cAMP multiple interactions ISO LEPR (Homo sapiens) 6480464 LEPR protein affects the reaction [LEP protein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased chemical synthesis of Progesterone]] and LEPR protein affects the reaction [LEP protein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR protein]] CTD PMID:19849856 Lepr Mouse acetamide decreases expression ISO Lepr (Rattus norvegicus) 6480464 acetamide results in decreased expression of LEPR mRNA CTD PMID:31881176 Lepr Mouse acetohydrazide decreases expression EXP 6480464 acetylhydrazine results in decreased expression of LEPR mRNA CTD PMID:15282401 Lepr Mouse acetylcholine multiple interactions EXP 6480464 acetovanillone inhibits the reaction [LEPR gene mutant form results in decreased susceptibility to Acetylcholine] more ... CTD PMID:19478208 Lepr Mouse acetylcholine decreases response to substance EXP 6480464 LEPR gene mutant form results in decreased susceptibility to Acetylcholine CTD PMID:19478208 Lepr Mouse acrolein multiple interactions ISO LEPR (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of and results in increased oxidation of LEPR mRNA more ... CTD PMID:32699268 and PMID:32845096 Lepr Mouse aflatoxin B1 decreases expression ISO Lepr (Rattus norvegicus) 6480464 Aflatoxin B1 results in decreased expression of LEPR mRNA CTD PMID:23630614 more ... Lepr Mouse aflatoxin B1 decreases expression ISO LEPR (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of LEPR mRNA CTD PMID:27153756 Lepr Mouse aldehydo-D-glucosamine affects response to substance ISO Lepr (Rattus norvegicus) 6480464 LEPR protein affects the susceptibility to Glucosamine CTD PMID:33345901 Lepr Mouse aldehydo-D-glucosamine multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [LEPR protein affects the susceptibility to Glucosamine] which affects the expression of ALB protein CTD PMID:33345901 Lepr Mouse aldehydo-D-glucose affects abundance EXP 6480464 LEPR affects the abundance of Glucose and LEPR protein affects the abundance of Glucose CTD PMID:16427799 and PMID:20567778 Lepr Mouse aldehydo-D-glucose increases expression ISO Lepr (Rattus norvegicus) 6480464 Glucose results in increased expression of LEPR protein CTD PMID:24399619 Lepr Mouse aldehydo-D-glucose multiple interactions EXP 6480464 Hesperidin affects the reaction [LEPR protein affects the abundance of Glucose] and naringin affects the reaction [LEPR protein affects the abundance of Glucose] CTD PMID:16427799 Lepr Mouse aldehydo-D-glucose multiple interactions ISO Lepr (Rattus norvegicus) 6480464 naringin inhibits the reaction [Glucose results in increased expression of LEPR protein] CTD PMID:24399619 Lepr Mouse aldehydo-D-glucose decreases response to substance EXP 6480464 LEPR results in decreased susceptibility to Glucose CTD PMID:20567778 Lepr Mouse all-trans-retinoic acid multiple interactions EXP 6480464 [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of LEPR mRNA CTD PMID:36189433 Lepr Mouse all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of LEPR mRNA CTD PMID:36189433 Lepr Mouse allantoin affects abundance EXP 6480464 LEPR affects the abundance of Allantoin CTD PMID:20567778 Lepr Mouse allethrin multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of LEPR protein CTD PMID:34896426 Lepr Mouse allopurinol multiple interactions ISO Lepr (Rattus norvegicus) 6480464 Allopurinol inhibits the reaction [Fructose results in increased expression of and results in increased phosphorylation of LEPR protein] CTD PMID:22426011 Lepr Mouse alpha-pinene multiple interactions ISO LEPR (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of and results in increased oxidation of LEPR mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of and results in increased oxidation of LEPR mRNA CTD PMID:32699268 Lepr Mouse alpha-Zearalanol multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of LEPR mRNA CTD PMID:35163327 Lepr Mouse ammonium chloride affects expression ISO Lepr (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of LEPR mRNA CTD PMID:16483693 Lepr Mouse anthra[1,9-cd]pyrazol-6(2H)-one affects response to substance EXP 6480464 LEPR protein affects the susceptibility to pyrazolanthrone CTD PMID:22933112 Lepr Mouse apocynin multiple interactions EXP 6480464 acetovanillone inhibits the reaction [LEPR gene mutant form results in decreased susceptibility to Acetylcholine] and acetovanillone inhibits the reaction [LEPR gene mutant form results in increased abundance of Superoxides] CTD PMID:19478208 Lepr Mouse aristolochic acid A decreases expression ISO LEPR (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of LEPR mRNA CTD PMID:33212167 Lepr Mouse arsane decreases expression EXP 6480464 Arsenic results in decreased expression of LEPR mRNA CTD PMID:19654921 Lepr Mouse arsane decreases expression ISO LEPR (Homo sapiens) 6480464 Arsenic results in decreased expression of LEPR mRNA CTD PMID:38036231 Lepr Mouse arsane affects methylation ISO LEPR (Homo sapiens) 6480464 Arsenic affects the methylation of LEPR gene CTD PMID:25304211 Lepr Mouse arsenic atom decreases expression EXP 6480464 Arsenic results in decreased expression of LEPR mRNA CTD PMID:19654921 Lepr Mouse arsenic atom decreases expression ISO LEPR (Homo sapiens) 6480464 Arsenic results in decreased expression of LEPR mRNA CTD PMID:38036231 Lepr Mouse arsenic atom affects methylation ISO LEPR (Homo sapiens) 6480464 Arsenic affects the methylation of LEPR gene CTD PMID:25304211 Lepr Mouse astaxanthin multiple interactions EXP 6480464 astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of AIFM1 mRNA] more ... CTD PMID:16964424 Lepr Mouse benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of LEPR mRNA CTD PMID:19770486 Lepr Mouse benzo[a]pyrene affects methylation ISO LEPR (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of LEPR 5' UTR CTD PMID:27901495 Lepr Mouse benzo[a]pyrene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of LEPR mRNA CTD PMID:27858113 Lepr Mouse benzo[a]pyrene decreases expression ISO LEPR (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of LEPR mRNA CTD PMID:22316170 Lepr Mouse benzo[a]pyrene decreases expression ISO Lepr (Rattus norvegicus) 6480464 Benzo(a)pyrene results in decreased expression of LEPR mRNA CTD PMID:21839799 Lepr Mouse benzo[b]fluoranthene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of LEPR mRNA CTD PMID:27858113 Lepr Mouse beta-D-glucosamine multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [LEPR protein affects the susceptibility to Glucosamine] which affects the expression of ALB protein CTD PMID:33345901 Lepr Mouse beta-D-glucosamine affects response to substance ISO Lepr (Rattus norvegicus) 6480464 LEPR protein affects the susceptibility to Glucosamine CTD PMID:33345901 Lepr Mouse beta-naphthoflavone multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of LEPR mRNA CTD PMID:18164116 Lepr Mouse bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of LEPR mRNA CTD PMID:35550907 Lepr Mouse bisphenol A increases expression ISO LEPR (Homo sapiens) 6480464 bisphenol A results in increased expression of LEPR mRNA and bisphenol A results in increased expression of LEPR protein CTD PMID:22343039 Lepr Mouse bisphenol A decreases methylation ISO LEPR (Homo sapiens) 6480464 bisphenol A results in decreased methylation of LEPR gene CTD PMID:31601247 Lepr Mouse bisphenol A affects expression ISO Lepr (Rattus norvegicus) 6480464 bisphenol A affects the expression of LEPR mRNA CTD PMID:32145629 Lepr Mouse bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of LEPR mRNA CTD PMID:30951980 Lepr Mouse bisphenol A decreases expression ISO Lepr (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of LEPR mRNA CTD PMID:25181051 Lepr Mouse bisphenol A multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of LEPR mRNA CTD PMID:26496021 Lepr Mouse bisphenol F increases expression EXP 6480464 bisphenol F results in increased expression of LEPR mRNA CTD PMID:30951980 Lepr Mouse bromodichloromethane multiple interactions EXP 6480464 LEPR protein affects the reaction [[Dietary Fats co-treated with bromodichloromethane] affects the localization of NCF2 protein] and LEPR protein results in decreased susceptibility to [Dietary Fats co-treated with bromodichloromethane] CTD PMID:23438451 Lepr Mouse butanal decreases expression ISO LEPR (Homo sapiens) 6480464 butyraldehyde results in decreased expression of LEPR mRNA CTD PMID:26079696 Lepr Mouse butyric acid affects abundance EXP 6480464 LEPR affects the abundance of Butyric Acid CTD PMID:20567778 Lepr Mouse cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of LEPR mRNA CTD PMID:37325564 Lepr Mouse cadmium dichloride decreases expression ISO LEPR (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of LEPR mRNA CTD PMID:38568856 Lepr Mouse cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of LEPR mRNA CTD PMID:37325564 Lepr Mouse caffeine increases expression ISO Lepr (Rattus norvegicus) 6480464 Caffeine results in increased expression of LEPR mRNA CTD PMID:22583948 Lepr Mouse caffeine decreases expression ISO Lepr (Rattus norvegicus) 6480464 Caffeine results in decreased expression of LEPR mRNA CTD PMID:26367767 Lepr Mouse calcium atom affects expression ISO Lepr (Rattus norvegicus) 6480464 Calcium affects the expression of LEPR mRNA CTD PMID:15913539 Lepr Mouse calcium(0) affects expression ISO Lepr (Rattus norvegicus) 6480464 Calcium affects the expression of LEPR mRNA CTD PMID:15913539 Lepr Mouse captopril affects response to substance EXP 6480464 LEPR protein affects the susceptibility to Captopril CTD PMID:28130181 Lepr Mouse captopril multiple interactions EXP 6480464 Captopril inhibits the reaction [LEPR protein affects the expression of AGT protein] more ... CTD PMID:28130181 Lepr Mouse carbon nanotube decreases expression EXP 6480464 Nanotubes more ... CTD PMID:25554681 Lepr Mouse carbon nanotube increases expression EXP 6480464 Nanotubes and Carbon results in increased expression of LEPR mRNA CTD PMID:25620056 Lepr Mouse CGP 52608 multiple interactions ISO LEPR (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to LEPR gene] CTD PMID:28238834 Lepr Mouse chloroquine increases expression EXP 6480464 Chloroquine results in increased expression of LEPR protein CTD PMID:31199479 Lepr Mouse chlorpyrifos increases expression EXP 6480464 Chlorpyrifos results in increased expression of LEPR mRNA CTD PMID:37019170 Lepr Mouse cholesterol multiple interactions EXP 6480464 Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased abundance of Cholesterol] CTD PMID:29988851 Lepr Mouse cholesterol increases abundance EXP 6480464 LEPR gene mutant form results in increased abundance of Cholesterol CTD PMID:29988851 Lepr Mouse choline affects abundance EXP 6480464 LEPR affects the abundance of Choline CTD PMID:20567778 Lepr Mouse choline multiple interactions EXP 6480464 [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of LEPR mRNA more ... CTD PMID:20938992 more ... Lepr Mouse chromium atom multiple interactions EXP 6480464 LEPR gene mutant form promotes the reaction [[Niacin binds to Chromium] which results in decreased expression of BTC mRNA] more ... CTD PMID:16940432 Lepr Mouse chrysene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of LEPR mRNA CTD PMID:27858113 Lepr Mouse ciguatoxin CTX1B affects expression EXP 6480464 Ciguatoxins affects the expression of LEPR mRNA CTD PMID:18353800 Lepr Mouse cisplatin multiple interactions ISO LEPR (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of LEPR mRNA CTD PMID:27392435 Lepr Mouse citric acid affects abundance EXP 6480464 LEPR affects the abundance of Citric Acid CTD PMID:20567778 Lepr Mouse clofibrate increases expression ISO Lepr (Rattus norvegicus) 6480464 Clofibrate results in increased expression of LEPR mRNA CTD PMID:22008536 Lepr Mouse clofibric acid multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of LEPR mRNA CTD PMID:17602206 Lepr Mouse coumestrol decreases expression ISO LEPR (Homo sapiens) 6480464 Coumestrol results in decreased expression of LEPR mRNA CTD PMID:19167446 Lepr Mouse coumestrol multiple interactions ISO LEPR (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of LEPR mRNA CTD PMID:19167446 Lepr Mouse creatinine affects abundance EXP 6480464 LEPR affects the abundance of Creatinine CTD PMID:20567778 Lepr Mouse creatinine multiple interactions EXP 6480464 Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased abundance of Creatinine] and swietenine inhibits the reaction [LEPR gene mutant form results in increased abundance of Creatinine] CTD PMID:29988851 and PMID:36066211 Lepr Mouse creatinine increases abundance EXP 6480464 LEPR gene mutant form results in increased abundance of Creatinine CTD PMID:29988851 and PMID:36066211 Lepr Mouse crocidolite asbestos decreases expression EXP 6480464 Asbestos and Crocidolite results in decreased expression of LEPR mRNA CTD PMID:29279043 Lepr Mouse cyanocob(III)alamin multiple interactions EXP 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of LEPR mRNA CTD PMID:33549593 Lepr Mouse cycloheximide multiple interactions EXP 6480464 LEP protein inhibits the reaction [Cycloheximide results in decreased expression of LEPR protein] CTD PMID:31199479 Lepr Mouse cycloheximide decreases expression EXP 6480464 Cycloheximide results in decreased expression of LEPR protein CTD PMID:31199479 Lepr Mouse cyclosporin A decreases expression ISO LEPR (Homo sapiens) 6480464 Cyclosporine results in decreased expression of LEPR mRNA CTD PMID:27989131 Lepr Mouse cyhalothrin multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of LEPR protein CTD PMID:34896426 Lepr Mouse cypermethrin multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of LEPR protein CTD PMID:34896426 Lepr Mouse cyromazine multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [2-amino-3-chloro-1 and 4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in decreased expression of LEPR mRNA CTD PMID:29321614 Lepr Mouse cytarabine decreases expression ISO LEPR (Homo sapiens) 6480464 Cytarabine results in decreased expression of LEPR mRNA CTD PMID:21198554 Lepr Mouse D-glucose decreases response to substance EXP 6480464 LEPR results in decreased susceptibility to Glucose CTD PMID:20567778 Lepr Mouse D-glucose increases expression ISO Lepr (Rattus norvegicus) 6480464 Glucose results in increased expression of LEPR protein CTD PMID:24399619 Lepr Mouse D-glucose multiple interactions ISO Lepr (Rattus norvegicus) 6480464 naringin inhibits the reaction [Glucose results in increased expression of LEPR protein] CTD PMID:24399619 Lepr Mouse D-glucose multiple interactions EXP 6480464 Hesperidin affects the reaction [LEPR protein affects the abundance of Glucose] and naringin affects the reaction [LEPR protein affects the abundance of Glucose] CTD PMID:16427799 Lepr Mouse D-glucose affects abundance EXP 6480464 LEPR affects the abundance of Glucose and LEPR protein affects the abundance of Glucose CTD PMID:16427799 and PMID:20567778 Lepr Mouse dactolisib multiple interactions EXP 6480464 LEPR affects the reaction [dactolisib results in decreased phosphorylation of AKT1 protein] CTD PMID:22949526 Lepr Mouse decabromodiphenyl ether decreases expression ISO Lepr (Rattus norvegicus) 6480464 decabromobiphenyl ether results in decreased expression of LEPR mRNA CTD PMID:23640034 Lepr Mouse decabromodiphenyl ether increases expression ISO Lepr (Rattus norvegicus) 6480464 decabromobiphenyl ether results in increased expression of LEPR mRNA CTD PMID:23640034 and PMID:23914054 Lepr Mouse dexamethasone decreases expression ISO Lepr (Rattus norvegicus) 10412034 Dexamthasone decreases Lepr mRNA and protein expression in placenta RGD Lepr Mouse dibenz[a,h]anthracene increases expression EXP 6480464 1 more ... CTD PMID:26377693 Lepr Mouse dibutyl phthalate increases expression ISO Lepr (Rattus norvegicus) 6480464 Dibutyl Phthalate results in increased expression of LEPR mRNA CTD PMID:21266533 Lepr Mouse dichloroacetic acid increases expression EXP 6480464 Dichloroacetic Acid results in increased expression of LEPR mRNA CTD PMID:28962523 Lepr Mouse diclofenac affects expression EXP 6480464 Diclofenac affects the expression of LEPR mRNA CTD PMID:26934552 Lepr Mouse diclofenac increases expression EXP 6480464 Diclofenac results in increased expression of LEPR protein CTD PMID:26934552 Lepr Mouse dicrotophos increases expression ISO LEPR (Homo sapiens) 6480464 dicrotophos results in increased expression of LEPR mRNA CTD PMID:28302478 Lepr Mouse diethyl maleate decreases expression ISO Lepr (Rattus norvegicus) 6480464 diethyl maleate results in decreased expression of LEPR mRNA CTD PMID:21161181 Lepr Mouse dioxygen increases expression ISO LEPR (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of LEPR mRNA CTD PMID:26516004 Lepr Mouse dioxygen multiple interactions EXP 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of LEPR mRNA CTD PMID:30529165 Lepr Mouse diquat decreases expression EXP 6480464 Diquat results in decreased expression of LEPR mRNA CTD PMID:36851058 Lepr Mouse dobutamine affects response to substance EXP 6480464 LEPR protein affects the susceptibility to Dobutamine CTD PMID:20175764 Lepr Mouse dorsomorphin multiple interactions ISO LEPR (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LEPR mRNA CTD PMID:27188386 Lepr Mouse doxorubicin decreases expression ISO LEPR (Homo sapiens) 6480464 Doxorubicin results in decreased expression of LEPR mRNA CTD PMID:29803840 Lepr Mouse Enterolactone multiple interactions ISO LEPR (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of LEPR mRNA CTD PMID:19167446 Lepr Mouse epoxiconazole decreases expression EXP 6480464 epoxiconazole results in decreased expression of LEPR mRNA CTD PMID:35436446 Lepr Mouse estrone multiple interactions EXP 6480464 Estrone inhibits the reaction [LEPR gene mutant form inhibits the reaction [EGFR protein results in increased phosphorylation of EGFR protein]] and Estrone inhibits the reaction [LEPR gene mutant form results in decreased expression of EGFR mRNA] CTD PMID:1753381 Lepr Mouse ethanol multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [LEPR gene mutant form results in increased susceptibility to Ethanol] which results in decreased abundance of Zinc more ... CTD PMID:15475485 and PMID:18227024 Lepr Mouse ethanol multiple interactions EXP 6480464 [lard co-treated with Ethanol co-treated with High Fructose Corn Syrup] results in decreased expression of LEPR protein more ... CTD PMID:24155903 and PMID:37023972 Lepr Mouse ethanol decreases expression ISO Lepr (Rattus norvegicus) 6480464 Ethanol results in decreased expression of LEPR mRNA CTD PMID:16098508 Lepr Mouse ethanol increases response to substance ISO Lepr (Rattus norvegicus) 6480464 LEPR gene mutant form results in increased susceptibility to Ethanol CTD PMID:15475485 Lepr Mouse ethylmalonic acid affects abundance EXP 6480464 LEPR affects the abundance of Methylmalonic Acid CTD PMID:20567778 Lepr Mouse fentin chloride increases expression ISO Lepr (Rattus norvegicus) 6480464 triphenyltin chloride results in increased expression of LEPR mRNA CTD PMID:37156404 Lepr Mouse fenvalerate increases expression ISO Lepr (Rattus norvegicus) 6480464 fenvalerate results in increased expression of LEPR mRNA CTD PMID:30307764 Lepr Mouse fenvalerate multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of LEPR protein CTD PMID:34896426 Lepr Mouse flutamide decreases expression ISO Lepr (Rattus norvegicus) 6480464 Flutamide results in decreased expression of LEPR mRNA CTD PMID:24136188 Lepr Mouse folic acid multiple interactions EXP 6480464 [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of LEPR mRNA more ... CTD PMID:20938992 more ... Lepr Mouse folic acid decreases expression EXP 6480464 Folic Acid results in decreased expression of LEPR mRNA CTD PMID:25629700 Lepr Mouse formic acid affects abundance EXP 6480464 LEPR affects the abundance of formic acid CTD PMID:20567778 Lepr Mouse fructose multiple interactions ISO Lepr (Rattus norvegicus) 6480464 Allopurinol inhibits the reaction [Fructose results in increased expression of and results in increased phosphorylation of LEPR protein] more ... CTD PMID:22426011 Lepr Mouse fumaric acid affects abundance EXP 6480464 LEPR affects the abundance of fumaric acid CTD PMID:20567778 Lepr Mouse furan increases methylation ISO Lepr (Rattus norvegicus) 6480464 furan results in increased methylation of LEPR gene CTD PMID:22079235 Lepr Mouse galactaric acid affects abundance EXP 6480464 LEPR affects the abundance of galactaric acid CTD PMID:20567778 Lepr Mouse gefitinib decreases expression ISO LEPR (Homo sapiens) 6480464 gefitinib results in decreased expression of LEPR mRNA CTD PMID:16685379 Lepr Mouse genistein decreases expression ISO LEPR (Homo sapiens) 6480464 Genistein results in decreased expression of LEPR mRNA CTD PMID:26865667 Lepr Mouse glucagon multiple interactions EXP 6480464 Glucagon analog inhibits the reaction [[LEPR gene mutant form results in increased oxidation of Lipids] which results in increased abundance of Thiobarbituric Acid Reactive Substances] more ... CTD PMID:29988851 Lepr Mouse glucose decreases response to substance EXP 6480464 LEPR results in decreased susceptibility to Glucose CTD PMID:20567778 Lepr Mouse glucose increases expression ISO Lepr (Rattus norvegicus) 6480464 Glucose results in increased expression of LEPR protein CTD PMID:24399619 Lepr Mouse glucose multiple interactions ISO Lepr (Rattus norvegicus) 6480464 naringin inhibits the reaction [Glucose results in increased expression of LEPR protein] CTD PMID:24399619 Lepr Mouse glucose multiple interactions EXP 6480464 Hesperidin affects the reaction [LEPR protein affects the abundance of Glucose] and naringin affects the reaction [LEPR protein affects the abundance of Glucose] CTD PMID:16427799 Lepr Mouse glucose affects abundance EXP 6480464 LEPR affects the abundance of Glucose and LEPR protein affects the abundance of Glucose CTD PMID:16427799 and PMID:20567778 Lepr Mouse glutaric acid affects abundance EXP 6480464 LEPR affects the abundance of glutaric acid CTD PMID:20567778 Lepr Mouse glutathione multiple interactions ISO Lepr (Rattus norvegicus) 6480464 LEPR gene mutant form results in increased oxidation of and results in decreased abundance of Glutathione CTD PMID:29743445 Lepr Mouse glycidol decreases expression ISO Lepr (Rattus norvegicus) 6480464 glycidol results in decreased expression of LEPR mRNA CTD PMID:24915197 Lepr Mouse glycine betaine multiple interactions EXP 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of LEPR mRNA CTD PMID:33549593 Lepr Mouse glyphosate decreases expression ISO LEPR (Homo sapiens) 6480464 Glyphosate results in decreased expression of LEPR mRNA CTD PMID:31295307 Lepr Mouse gypenoside LXXV multiple interactions EXP 6480464 gypenoside LXXV inhibits the reaction [LEPR gene mutant form results in increased expression of CCL2 protein] more ... CTD PMID:35192202 Lepr Mouse harmine multiple interactions EXP 6480464 Harmine affects the reaction [LEPR protein affects the susceptibility to INS1 protein] CTD PMID:27805061 Lepr Mouse hesperidin multiple interactions EXP 6480464 Hesperidin affects the reaction [LEPR protein affects the abundance of Glucose] more ... CTD PMID:16427799 Lepr Mouse hexanoic acid affects abundance EXP 6480464 LEPR affects the abundance of hexanoic acid CTD PMID:20567778 Lepr Mouse high-density lipoprotein cholesterol affects abundance ISO LEPR (Homo sapiens) 6480464 LEPR polymorphism affects the abundance of Cholesterol and HDL CTD PMID:14625131 Lepr Mouse hydrazine increases expression ISO Lepr (Rattus norvegicus) 6480464 hydrazine results in increased expression of LEPR mRNA CTD PMID:15370871 Lepr Mouse hydrochlorothiazide increases response to substance EXP 6480464 LEPR mutant form results in increased susceptibility to Hydrochlorothiazide CTD PMID:22949526 Lepr Mouse hydrogen peroxide increases response to substance EXP 6480464 LEPR mutant form results in increased susceptibility to Hydrogen Peroxide CTD PMID:27151219 Lepr Mouse indoxyl sulfate affects abundance EXP 6480464 LEPR affects the abundance of Indican CTD PMID:20567778 Lepr Mouse isobutyric acid affects abundance EXP 6480464 LEPR affects the abundance of isobutyric acid CTD PMID:20567778 Lepr Mouse isocaproic acid affects abundance EXP 6480464 LEPR affects the abundance of isocaproic acid CTD PMID:20567778 Lepr Mouse isoprenaline increases expression ISO Lepr (Rattus norvegicus) 6480464 Isoproterenol results in increased expression of LEPR mRNA and Isoproterenol results in increased expression of LEPR protein CTD PMID:20307649 Lepr Mouse isoprenaline affects response to substance EXP 6480464 LEPR protein affects the susceptibility to Isoproterenol CTD PMID:36776448 Lepr Mouse isoprenaline multiple interactions ISO Lepr (Rattus norvegicus) 6480464 CPU0213 inhibits the reaction [Isoproterenol results in increased expression of LEPR mRNA] and CPU0213 inhibits the reaction [Isoproterenol results in increased expression of LEPR protein] CTD PMID:20307649 Lepr Mouse isovaleric acid affects abundance EXP 6480464 LEPR affects the abundance of isovaleric acid CTD PMID:20567778 Lepr Mouse ketamine decreases expression ISO LEPR (Homo sapiens) 6480464 Ketamine results in decreased expression of LEPR protein CTD PMID:36907275 Lepr Mouse ketamine multiple interactions ISO LEPR (Homo sapiens) 6480464 lipoxin A4 methyl ester inhibits the reaction [Ketamine results in decreased expression of LEPR protein] CTD PMID:36907275 Lepr Mouse L-methionine affects abundance EXP 6480464 LEPR affects the abundance of Methionine CTD PMID:20567778 Lepr Mouse L-methionine multiple interactions EXP 6480464 [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of LEPR mRNA more ... CTD PMID:20938992 more ... Lepr Mouse lead diacetate decreases expression ISO LEPR (Homo sapiens) 6480464 lead acetate results in decreased expression of LEPR mRNA CTD PMID:38568856 Lepr Mouse lipopolysaccharide multiple interactions ISO Lepr (Rattus norvegicus) 6480464 Lipopolysaccharides inhibits the reaction [Thioacetamide results in decreased expression of LEPR mRNA] CTD PMID:17621560 Lepr Mouse LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [LEPR gene mutant form results in decreased expression of SOD2 protein] more ... CTD PMID:23159718 Lepr Mouse malonic acid affects abundance EXP 6480464 LEPR affects the abundance of malonic acid CTD PMID:20567778 Lepr Mouse mercury atom decreases expression ISO LEPR (Homo sapiens) 6480464 Mercury results in decreased expression of LEPR mRNA CTD PMID:16823088 Lepr Mouse mercury(0) decreases expression ISO LEPR (Homo sapiens) 6480464 Mercury results in decreased expression of LEPR mRNA CTD PMID:16823088 Lepr Mouse methylmalonic acid affects abundance EXP 6480464 LEPR affects the abundance of Methylmalonic Acid CTD PMID:20567778 Lepr Mouse methylmercury chloride decreases expression ISO LEPR (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of LEPR mRNA CTD PMID:23179753 Lepr Mouse methylmercury chloride affects expression EXP 6480464 methylmercuric chloride affects the expression of LEPR mRNA CTD PMID:33338554 Lepr Mouse methylmercury chloride increases expression ISO LEPR (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of LEPR mRNA CTD PMID:28001369 Lepr Mouse metyrapone increases expression ISO Lepr (Rattus norvegicus) 10412034 Metyrapone increases Lepr mRNA expression in placenta RGD Lepr Mouse mifepristone decreases expression ISO Lepr (Rattus norvegicus) 6480464 Mifepristone results in decreased expression of LEPR mRNA CTD PMID:25972201 Lepr Mouse MK-2206 multiple interactions EXP 6480464 LEPR affects the reaction [MK 2206 results in decreased phosphorylation of AKT1 protein] CTD PMID:22949526 Lepr Mouse mono(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of LEPR mRNA CTD PMID:36189433 Lepr Mouse morphine increases expression EXP 6480464 Morphine results in increased expression of LEPR mRNA CTD PMID:20144693 Lepr Mouse N-[3-(aminomethyl)benzyl]acetamidine increases response to substance ISO Lepr (Rattus norvegicus) 6480464 LEPR gene mutant form results in increased susceptibility to N-(3-(aminomethyl)benzyl)acetamidine CTD PMID:30689673 Lepr Mouse N-ethyl-N-nitrosourea increases mutagenesis EXP 6480464 Ethylnitrosourea results in increased mutagenesis of LEPR gene CTD PMID:16724327 Lepr Mouse N-methyl-6-pyridone-3-carboxamide affects abundance EXP 6480464 LEPR affects the abundance of N'-methyl-2-pyridone-5-carboxamide CTD PMID:20567778 Lepr Mouse N-methylnicotinate affects abundance EXP 6480464 LEPR affects the abundance of trigonelline CTD PMID:20567778 Lepr Mouse N-nitrosodiethylamine multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of LEPR mRNA and [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of LEPR mRNA CTD PMID:17602206 and PMID:18164116 Lepr Mouse N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of LEPR mRNA CTD PMID:24535843 Lepr Mouse N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of LEPR mRNA CTD PMID:24535843 Lepr Mouse naringin multiple interactions EXP 6480464 naringin affects the reaction [LEPR protein affects the abundance of Glucose] more ... CTD PMID:16427799 Lepr Mouse naringin multiple interactions ISO Lepr (Rattus norvegicus) 6480464 naringin inhibits the reaction [Glucose results in increased expression of LEPR protein] CTD PMID:24399619 Lepr Mouse nickel atom multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [nickel sulfate results in increased abundance of Nickel] which results in increased expression of LEPR mRNA CTD PMID:31734292 Lepr Mouse nickel atom decreases expression ISO LEPR (Homo sapiens) 6480464 Nickel results in decreased expression of LEPR mRNA CTD PMID:24768652 Lepr Mouse nickel sulfate multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [nickel sulfate results in increased abundance of Nickel] which results in increased expression of LEPR mRNA CTD PMID:31734292 Lepr Mouse Nicotinamide N-oxide affects abundance EXP 6480464 LEPR affects the abundance of nicotinamide N-oxide CTD PMID:20567778 Lepr Mouse nicotine increases expression ISO Lepr (Rattus norvegicus) 6480464 Nicotine results in increased expression of LEPR mRNA CTD PMID:22265867 Lepr Mouse nicotine decreases expression ISO Lepr (Rattus norvegicus) 6480464 Nicotine results in decreased expression of LEPR mRNA CTD PMID:29155039 Lepr Mouse nicotinic acid multiple interactions EXP 6480464 LEPR gene mutant form promotes the reaction [[Niacin binds to Chromium] which results in decreased expression of BTC mRNA] more ... CTD PMID:16940432 Lepr Mouse orotic acid affects abundance EXP 6480464 LEPR affects the abundance of Orotic Acid CTD PMID:20567778 Lepr Mouse ozone multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of LEPR mRNA more ... CTD PMID:16373670 more ... Lepr Mouse ozone multiple interactions ISO LEPR (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of and results in increased oxidation of LEPR mRNA more ... CTD PMID:32699268 and PMID:32845096 Lepr Mouse ozone decreases expression ISO Lepr (Rattus norvegicus) 6480464 Ozone results in decreased expression of LEPR mRNA CTD PMID:26667333 Lepr Mouse ozone increases response to substance EXP 6480464 LEPR gene mutant form results in increased susceptibility to Ozone CTD PMID:16373670 Lepr Mouse paracetamol multiple interactions EXP 6480464 PANX1 gene mutant form inhibits the reaction [Acetaminophen results in decreased expression of LEPR mRNA] CTD PMID:29246445 Lepr Mouse paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of LEPR mRNA CTD PMID:29246445 Lepr Mouse PCB138 multiple interactions EXP 6480464 [2 more ... CTD PMID:25510870 Lepr Mouse pentanal decreases expression ISO LEPR (Homo sapiens) 6480464 pentanal results in decreased expression of LEPR mRNA CTD PMID:26079696 Lepr Mouse perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of LEPR mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of LEPR mRNA CTD PMID:36331819 Lepr Mouse perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of LEPR mRNA CTD PMID:17681415 Lepr Mouse perfluorooctanoic acid increases expression ISO LEPR (Homo sapiens) 6480464 perfluorooctanoic acid results in increased expression of LEPR mRNA CTD PMID:36326898 Lepr Mouse perfluorooctanoic acid multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of LEPR mRNA CTD PMID:35163327 Lepr Mouse phenformin increases response to substance ISO Lepr (Rattus norvegicus) 6480464 LEPR gene mutant form results in increased susceptibility to Phenformin CTD PMID:29743445 Lepr Mouse phenobarbital increases expression ISO Lepr (Rattus norvegicus) 6480464 Phenobarbital results in increased expression of LEPR mRNA CTD PMID:22008536 Lepr Mouse phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of LEPR mRNA CTD PMID:23091169 Lepr Mouse phenobarbital multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of LEPR mRNA CTD PMID:24535843 Lepr Mouse phenylmercury acetate increases expression ISO LEPR (Homo sapiens) 6480464 Phenylmercuric Acetate results in increased expression of LEPR mRNA CTD PMID:26272509 Lepr Mouse phenylmercury acetate multiple interactions ISO LEPR (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LEPR mRNA CTD PMID:27188386 Lepr Mouse pioglitazone increases response to substance ISO Lepr (Rattus norvegicus) 6480464 LEPR gene mutant form results in increased susceptibility to Pioglitazone CTD PMID:29743445 Lepr Mouse pioglitazone multiple interactions EXP 6480464 Pioglitazone inhibits the reaction [LEPR protein affects the expression of OGG1 protein] and Pioglitazone inhibits the reaction [LEPR protein affects the expression of XRCC1 protein] CTD PMID:35472412 Lepr Mouse pirimicarb multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [2-amino-3-chloro-1 and 4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in decreased expression of LEPR mRNA CTD PMID:29321614 Lepr Mouse pirinixic acid multiple interactions ISO LEPR (Homo sapiens) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of LEPR mRNA CTD PMID:19710929 Lepr Mouse pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of LEPR mRNA CTD PMID:18301758 more ... Lepr Mouse pregnenolone 16alpha-carbonitrile decreases expression ISO Lepr (Rattus norvegicus) 6480464 Pregnenolone Carbonitrile results in decreased expression of LEPR mRNA CTD PMID:19162173 Lepr Mouse progesterone multiple interactions ISO LEPR (Homo sapiens) 6480464 LEPR protein affects the reaction [LEP protein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased chemical synthesis of Progesterone]] CTD PMID:19849856 Lepr Mouse propranolol increases expression ISO Lepr (Rattus norvegicus) 6480464 Propranolol results in increased expression of LEPR mRNA CTD PMID:24250662 Lepr Mouse pyrethrins decreases expression ISO Lepr (Rattus norvegicus) 6480464 Pyrethrins results in decreased expression of LEPR protein CTD PMID:34896426 Lepr Mouse quercetin multiple interactions ISO Lepr (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [Fructose results in increased expression of and results in increased phosphorylation of LEPR protein] CTD PMID:22426011 Lepr Mouse quercetin increases expression ISO LEPR (Homo sapiens) 6480464 Quercetin results in increased expression of LEPR mRNA and Quercetin results in increased expression of LEPR protein CTD PMID:22230496 Lepr Mouse rac-lactic acid affects abundance EXP 6480464 LEPR affects the abundance of Lactic Acid CTD PMID:20567778 Lepr Mouse raloxifene affects expression ISO Lepr (Rattus norvegicus) 1581837 Raloxifene decreases Lepr protein expression in adipose tissue at 7 weeks and increases it at 22 weeks RGD Lepr Mouse razoxane decreases expression ISO Lepr (Rattus norvegicus) 6480464 Razoxane results in decreased expression of LEPR mRNA CTD PMID:19915844 Lepr Mouse resveratrol multiple interactions EXP 6480464 Resveratrol inhibits the reaction [Dietary Fats results in increased expression of LEPR mRNA] more ... CTD PMID:19478208 and PMID:31881177 Lepr Mouse riddelliine increases expression ISO Lepr (Rattus norvegicus) 6480464 riddelliine results in increased expression of LEPR mRNA CTD PMID:18047727 Lepr Mouse rotenone increases expression ISO Lepr (Rattus norvegicus) 6480464 Rotenone results in increased expression of LEPR mRNA CTD PMID:28374803 Lepr Mouse rutin multiple interactions ISO Lepr (Rattus norvegicus) 6480464 Rutin inhibits the reaction [Fructose results in increased expression of and results in increased phosphorylation of LEPR protein] CTD PMID:22426011 Lepr Mouse SB 203580 affects response to substance EXP 6480464 LEPR protein affects the susceptibility to SB 203580 CTD PMID:22933112 Lepr Mouse SB 431542 multiple interactions EXP 6480464 4-(5-benzo(1 more ... CTD PMID:23159718 Lepr Mouse SB 431542 multiple interactions ISO LEPR (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LEPR mRNA CTD PMID:27188386 Lepr Mouse silicon dioxide decreases expression ISO LEPR (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of LEPR mRNA CTD PMID:25895662 Lepr Mouse silicon dioxide increases expression ISO Lepr (Rattus norvegicus) 6480464 Silicon Dioxide results in increased expression of LEPR mRNA CTD PMID:32721576 Lepr Mouse simvastatin affects response to substance ISO LEPR (Homo sapiens) 6480464 LEPR polymorphism affects the susceptibility to Simvastatin CTD PMID:14625131 and PMID:18854995 Lepr Mouse sodium arsenite multiple interactions EXP 6480464 LEPR gene mutant form inhibits the reaction [sodium arsenite results in increased abundance of Blood Glucose] more ... CTD PMID:25367288 Lepr Mouse sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of LEPR mRNA CTD PMID:37682722 Lepr Mouse sodium dichromate decreases expression ISO Lepr (Rattus norvegicus) 6480464 sodium bichromate results in decreased expression of LEPR mRNA CTD PMID:25993096 Lepr Mouse streptozocin multiple interactions EXP 6480464 [Streptozocin co-treated with Dietary Fats] results in increased expression of LEPR mRNA CTD PMID:29127188 Lepr Mouse succinic acid affects abundance EXP 6480464 LEPR affects the abundance of Succinic Acid CTD PMID:20567778 Lepr Mouse sucrose affects abundance EXP 6480464 LEPR affects the abundance of Sucrose CTD PMID:20567778 Lepr Mouse sulforaphane decreases expression EXP 6480464 sulforaphane results in decreased expression of LEPR mRNA CTD PMID:30529165 Lepr Mouse sulforaphane multiple interactions EXP 6480464 [LEPR protein affects the susceptibility to sulforaphane] which affects the expression of CNR2 protein CTD PMID:29143802 Lepr Mouse sulforaphane affects response to substance EXP 6480464 LEPR protein affects the susceptibility to sulforaphane CTD PMID:29143802 Lepr Mouse superoxide multiple interactions EXP 6480464 acetovanillone inhibits the reaction [LEPR gene mutant form results in increased abundance of Superoxides] and resveratrol inhibits the reaction [LEPR gene mutant form results in increased abundance of Superoxides] CTD PMID:19478208 Lepr Mouse superoxide increases abundance EXP 6480464 LEPR gene mutant form results in increased abundance of Superoxides CTD PMID:19478208 Lepr Mouse tacrine increases expression ISO Lepr (Rattus norvegicus) 6480464 Tacrine results in increased expression of LEPR mRNA CTD PMID:12832660 Lepr Mouse taurine affects abundance EXP 6480464 LEPR affects the abundance of Taurine CTD PMID:20567778 Lepr Mouse telmisartan multiple interactions EXP 6480464 Telmisartan affects the reaction [LEPR protein affects the abundance of ALB protein] and Telmisartan affects the reaction [LEPR protein affects the expression of OCLN mRNA] CTD PMID:34464088 Lepr Mouse testosterone affects abundance ISO Lepr (Rattus norvegicus) 6480464 LEPR protein affects the abundance of Testosterone CTD PMID:15093691 Lepr Mouse testosterone multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in decreased expression of LEPR mRNA CTD PMID:32741896 Lepr Mouse tetrachloromethane multiple interactions ISO Lepr (Rattus norvegicus) 6480464 Drugs and Chinese Herbal inhibits the reaction [[Carbon Tetrachloride co-treated with Ethanol] results in increased expression of LEPR protein] CTD PMID:18227024 Lepr Mouse tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of LEPR mRNA CTD PMID:31919559 Lepr Mouse tetraphene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of LEPR mRNA CTD PMID:27858113 Lepr Mouse thioacetamide multiple interactions ISO Lepr (Rattus norvegicus) 6480464 LEPR gene mutant form inhibits the reaction [Thioacetamide results in increased expression of TGFB1 mRNA] more ... CTD PMID:11984526 and PMID:17621560 Lepr Mouse thioacetamide decreases expression ISO Lepr (Rattus norvegicus) 6480464 Thioacetamide results in decreased expression of LEPR mRNA and Thioacetamide results in decreased expression of LEPR protein CTD PMID:17621560 more ... Lepr Mouse thiram multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [2-amino-3-chloro-1 and 4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in decreased expression of LEPR mRNA CTD PMID:29321614 Lepr Mouse titanium dioxide decreases expression EXP 6480464 titanium dioxide results in decreased expression of LEPR mRNA CTD PMID:23557971 Lepr Mouse topotecan affects response to substance ISO LEPR (Homo sapiens) 6480464 LEPR protein affects the susceptibility to Topotecan CTD PMID:16217747 Lepr Mouse tremolite asbestos decreases expression EXP 6480464 tremolite results in decreased expression of LEPR mRNA CTD PMID:29279043 Lepr Mouse tributylstannane decreases expression EXP 6480464 tributyltin results in decreased expression of LEPR mRNA CTD PMID:31939706 Lepr Mouse trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of LEPR mRNA CTD PMID:25549359 Lepr Mouse trichostatin A decreases expression ISO LEPR (Homo sapiens) 6480464 trichostatin A results in decreased expression of LEPR and trichostatin A results in decreased expression of LEPR mRNA CTD PMID:22560341 and PMID:24935251 Lepr Mouse trimellitic anhydride decreases expression EXP 6480464 trimellitic anhydride results in decreased expression of LEPR mRNA CTD PMID:19042947 Lepr Mouse triphenyl phosphate multiple interactions EXP 6480464 [tris(1 more ... CTD PMID:29112739 and PMID:32360330 Lepr Mouse triphenyl phosphate affects expression ISO LEPR (Homo sapiens) 6480464 triphenyl phosphate affects the expression of LEPR mRNA CTD PMID:37042841 Lepr Mouse Triptolide decreases expression EXP 6480464 triptolide results in decreased expression of LEPR mRNA CTD PMID:32835833 Lepr Mouse triptonide increases expression EXP 6480464 triptonide results in increased expression of LEPR mRNA CTD PMID:33045310 Lepr Mouse troglitazone increases response to substance ISO Lepr (Rattus norvegicus) 6480464 LEPR gene mutant form results in increased susceptibility to Troglitazone CTD PMID:29743445 Lepr Mouse urea increases abundance EXP 6480464 LEPR gene mutant form results in increased abundance of Urea CTD PMID:29988851 and PMID:36066211 Lepr Mouse urea multiple interactions EXP 6480464 Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased abundance of Urea] and swietenine inhibits the reaction [LEPR gene mutant form results in increased abundance of Urea] CTD PMID:29988851 and PMID:36066211 Lepr Mouse valeric acid affects abundance EXP 6480464 LEPR affects the abundance of n-pentanoic acid CTD PMID:20567778 Lepr Mouse valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of LEPR mRNA CTD PMID:24489787 Lepr Mouse valproic acid decreases expression ISO LEPR (Homo sapiens) 6480464 Valproic Acid results in decreased expression of LEPR mRNA CTD PMID:23179753 more ... Lepr Mouse valproic acid affects expression ISO LEPR (Homo sapiens) 6480464 Valproic Acid affects the expression of LEPR mRNA CTD PMID:25979313 Lepr Mouse zinc atom multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [LEPR gene mutant form results in increased susceptibility to Ethanol] which results in decreased abundance of Zinc CTD PMID:15475485 Lepr Mouse zinc atom multiple interactions EXP 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of LEPR mRNA and [Zinc deficiency co-treated with Ethanol] results in increased expression of LEPR mRNA CTD PMID:24155903 and PMID:33549593 Lepr Mouse zinc(0) multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [LEPR gene mutant form results in increased susceptibility to Ethanol] which results in decreased abundance of Zinc CTD PMID:15475485 Lepr Mouse zinc(0) multiple interactions EXP 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of LEPR mRNA and [Zinc deficiency co-treated with Ethanol] results in increased expression of LEPR mRNA CTD PMID:24155903 and PMID:33549593 Lepr Mouse ziram multiple interactions ISO Lepr (Rattus norvegicus) 6480464 [2-amino-3-chloro-1 and 4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in decreased expression of LEPR mRNA CTD PMID:29321614