Lepr (leptin receptor) - Rat Genome Database

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Gene: Lepr (leptin receptor) Mus musculus
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Symbol: Lepr
Name: leptin receptor
RGD ID: 10865
MGI Page MGI
Description: Enables leptin receptor activity. Involved in several processes, including glucose homeostasis; leptin-mediated signaling pathway; and positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including glial cell proliferation; glycogen metabolic process; and negative regulation of gluconeogenesis. Predicted to be located in extracellular space. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and skeleton. Used to study metabolic dysfunction-associated steatotic liver disease; obesity; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); liver disease (multiple); obesity; obstructive sleep apnea; and type 2 diabetes mellitus. Orthologous to human LEPR (leptin receptor).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: B219; db; diabetes; LE; LEP-R; Leprb; LEPROT; leptin receptor gene-related protein; MGC105189; Modb; Modb1; O; OB receptor; OB-; OB-RGRP; obese-; obese-like; obl; Obr
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394101,574,393 - 101,676,375 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4101,574,601 - 101,672,549 (+)EnsemblGRCm39 Ensembl
GRCm384101,717,137 - 101,815,352 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4101,717,404 - 101,815,352 (+)EnsemblGRCm38mm10GRCm38
MGSCv374101,390,012 - 101,487,959 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364101,215,371 - 101,313,237 (+)NCBIMGSCv36mm8
Celera4100,061,452 - 100,155,523 (+)NCBICelera
Cytogenetic Map4C6NCBI
cM Map446.96NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Albuminuria  (ISO)
Animal Disease Models  (ISO)
arteriosclerosis  (ISO)
bone disease  (ISO)
Breast Neoplasms  (ISO)
cardiomyopathy  (ISO)
Chronic Hepatitis B  (ISO)
Chronic Hepatitis C  (ISO)
chronic kidney disease  (ISO)
chronic obstructive pulmonary disease  (ISO)
cognitive disorder  (ISO)
congestive heart failure  (IEP,ISO)
coronary artery disease  (ISO)
Coronary Disease  (ISO)
Delayed Puberty  (ISO)
diabetes mellitus  (ISO)
Diabetic Cardiomyopathies  (ISO)
Diabetic Nephropathies  (ISO)
diabetic neuropathy  (ISO)
Diastolic Dysfunction  (ISO)
diastolic heart failure  (ISO)
dilated cardiomyopathy  (ISO)
Dyslipidemias  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
familial hyperlipidemia  (ISO)
Female Infertility  (ISO)
Fibrosis  (ISO)
genetic disease  (ISO)
gestational diabetes  (ISO)
Gliosis  (ISO)
glucose intolerance  (ISO)
granulosa cell tumor  (ISO)
hepatocellular carcinoma  (ISO)
hepatocellular clear cell carcinoma  (ISO)
Hepatomegaly  (ISO)
human immunodeficiency virus infectious disease  (ISO)
Hyperalgesia  (ISO)
hyperglycemia  (ISO)
hyperinsulinism  (ISO)
Hyperphagia  (ISO)
hypertension  (ISO)
hypogonadism  (ISO)
infertility  (IMP,ISO)
inherited metabolic disorder  (ISO)
Insulin Resistance  (ISO)
intellectual disability  (ISO)
kidney disease  (ISO)
kidney failure  (ISO)
Knee Osteoarthritis  (ISO)
Left Ventricular Hypertrophy  (ISO)
Leptin Receptor Deficiency  (ISO)
metabolic dysfunction-associated steatohepatitis  (ISO)
metabolic dysfunction-associated steatotic liver disease  (IAGP,ISO)
Metabolic Syndrome  (ISO)
morbid obesity  (ISO)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (ISO)
Nasal Polyps  (ISO)
nephritis  (ISO)
obesity  (IAGP,IEP,IMP,ISO)
obstructive sleep apnea  (ISO)
osteoporosis  (ISO)
Overweight  (ISO)
pancreas disease  (ISO)
pancreatitis  (ISO)
pituitary gland disease  (ISO)
Pneumococcal Pneumonia  (IMP)
pre-eclampsia  (ISO)
Precocious Puberty  (ISO)
primary biliary cholangitis  (ISO)
primary immunodeficiency disease  (ISO)
primary ovarian insufficiency  (ISO)
proteinuria  (ISO)
pulmonary fibrosis  (IMP)
pulmonary hypertension  (ISO)
renal fibrosis  (ISO)
Respiratory Tract Infections  (ISO)
Right Ventricular Hypertrophy  (ISO)
short bowel syndrome  (ISO)
sleep apnea  (ISO)
Spinal Fractures  (ISO)
steatotic liver disease  (ISO)
type 2 diabetes mellitus  (IAGP,IMP,ISO)
Varicose Ulcer  (ISO)
Ventricular Dysfunction, Left  (ISO)
Weight Gain  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
(N(omega)-L-arginino)succinic acid  (EXP)
(R)-carnitine  (EXP)
(R)-pantothenic acid  (EXP)
(S)-nicotine  (ISO)
1,2-dichloroethane  (EXP)
1-methylnicotinamide  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-amino-2-deoxy-D-galactopyranose  (EXP)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-hydroxy-4-methylvaleric acid  (EXP)
2-hydroxyisobutyric acid  (EXP)
2-hydroxypropanoic acid  (EXP)
2-methyl-4-chlorophenoxybutyric acid  (ISO)
2-oxoadipic acid  (EXP)
3-methyl-2-oxobutanoic acid  (EXP)
3-methyl-2-oxovaleric acid  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxy-TEMPO  (EXP)
4-phenylbutyric acid  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (EXP)
8-Br-cAMP  (ISO)
acetamide  (ISO)
acetohydrazide  (EXP)
acetylcholine  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (ISO)
aldehydo-D-glucose  (EXP,ISO)
allantoin  (EXP)
allethrin  (ISO)
allopurinol  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP)
apocynin  (EXP)
aristolochic acid A  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
astaxanthin  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
beta-D-glucosamine  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bromodichloromethane  (EXP)
butanal  (ISO)
butyric acid  (EXP)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
caffeine  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
captopril  (EXP)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chloroquine  (EXP)
chlorpyrifos  (EXP)
cholesterol  (EXP)
choline  (EXP)
chromium atom  (EXP)
chrysene  (EXP)
ciguatoxin CTX1B  (EXP)
cisplatin  (ISO)
citric acid  (EXP)
clofibrate  (ISO)
clofibric acid  (ISO)
coumestrol  (ISO)
creatinine  (EXP)
crocidolite asbestos  (EXP)
cyanocob(III)alamin  (EXP)
cycloheximide  (EXP)
cyclosporin A  (ISO)
cyhalothrin  (ISO)
cypermethrin  (ISO)
cyromazine  (ISO)
cytarabine  (ISO)
D-glucose  (EXP,ISO)
dactolisib  (EXP)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
dibenz[a,h]anthracene  (EXP)
dibutyl phthalate  (ISO)
dichloroacetic acid  (EXP)
diclofenac  (EXP)
dicrotophos  (ISO)
diethyl maleate  (ISO)
dioxygen  (EXP,ISO)
diquat  (EXP)
dobutamine  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
epoxiconazole  (EXP)
estrone  (EXP)
ethanol  (EXP,ISO)
ethylmalonic acid  (EXP)
fentin chloride  (ISO)
fenvalerate  (ISO)
flutamide  (ISO)
folic acid  (EXP)
formic acid  (EXP)
fructose  (ISO)
fumaric acid  (EXP)
furan  (ISO)
galactaric acid  (EXP)
gefitinib  (ISO)
genistein  (ISO)
glucagon  (EXP)
glucose  (EXP,ISO)
glutaric acid  (EXP)
glutathione  (ISO)
glycidol  (ISO)
glycine betaine  (EXP)
glyphosate  (ISO)
gypenoside LXXV  (EXP)
harmine  (EXP)
hesperidin  (EXP)
hexanoic acid  (EXP)
high-density lipoprotein cholesterol  (ISO)
hydrazine  (ISO)
hydrochlorothiazide  (EXP)
hydrogen peroxide  (EXP)
indoxyl sulfate  (EXP)
isobutyric acid  (EXP)
isocaproic acid  (EXP)
isoprenaline  (ISO)
isovaleric acid  (EXP)
ketamine  (ISO)
L-methionine  (EXP)
lipopolysaccharide  (ISO)
LY294002  (EXP)
malonic acid  (EXP)
mercury atom  (ISO)
mercury(0)  (ISO)
methylmalonic acid  (EXP)
methylmercury chloride  (EXP,ISO)
metyrapone  (ISO)
mifepristone  (ISO)
MK-2206  (EXP)
morphine  (EXP)
N-[3-(aminomethyl)benzyl]acetamidine  (ISO)
N-ethyl-N-nitrosourea  (EXP)
N-methyl-6-pyridone-3-carboxamide  (EXP)
N-methylnicotinate  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
naringin  (EXP,ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
Nicotinamide N-oxide  (EXP)
nicotine  (ISO)
nicotinic acid  (EXP)
orotic acid  (EXP)
ozone  (EXP,ISO)
paracetamol  (EXP)
PCB138  (EXP)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP,ISO)
phenformin  (ISO)
phenobarbital  (EXP,ISO)
phenylmercury acetate  (ISO)
pioglitazone  (EXP,ISO)
pirimicarb  (ISO)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
propranolol  (ISO)
pyrethrins  (ISO)
quercetin  (ISO)
rac-lactic acid  (EXP)
raloxifene  (ISO)
razoxane  (ISO)
resveratrol  (EXP)
riddelliine  (ISO)
rotenone  (ISO)
rutin  (ISO)
SB 203580  (EXP)
SB 431542  (EXP,ISO)
silicon dioxide  (ISO)
simvastatin  (ISO)
sodium arsenite  (EXP)
sodium dichromate  (ISO)
streptozocin  (EXP)
succinic acid  (EXP)
sucrose  (EXP)
sulforaphane  (EXP)
superoxide  (EXP)
tacrine  (ISO)
taurine  (EXP)
telmisartan  (EXP)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (EXP)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
tremolite asbestos  (EXP)
tributylstannane  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (EXP)
triphenyl phosphate  (EXP)
Triptolide  (EXP)
triptonide  (EXP)
troglitazone  (ISO)
urea  (EXP)
valeric acid  (EXP)
valproic acid  (EXP,ISO)
zinc atom  (EXP,ISO)
zinc(0)  (EXP,ISO)
ziram  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal acute inflammation  (IAGP)
abnormal adipose tissue morphology  (IAGP)
abnormal adipose tissue physiology  (IAGP)
abnormal adrenal gland zona reticularis morphology  (IEA)
abnormal aerobic respiration  (IAGP)
abnormal aorta morphology  (IAGP)
abnormal axon extension  (IAGP)
abnormal axon morphology  (IAGP)
abnormal behavior  (IAGP)
abnormal blood circulation  (IAGP)
abnormal blood homeostasis  (IAGP)
abnormal body composition  (IAGP)
abnormal body temperature  (IAGP)
abnormal body temperature homeostasis  (IAGP)
abnormal body weight  (IAGP)
abnormal bone structure  (IEA)
abnormal carbon dioxide production  (IAGP)
abnormal cardiovascular system physiology  (IAGP)
abnormal CD4-positive, alpha beta T cell morphology  (IAGP)
abnormal CD8-positive, alpha beta T cell morphology  (IAGP)
abnormal chemokine level  (IAGP)
abnormal chemokine secretion  (IAGP)
abnormal circadian temperature homeostasis  (IAGP)
abnormal circulating cholesterol level  (IAGP)
abnormal circulating glucose level  (IAGP)
abnormal circulating insulin level  (IAGP)
abnormal circulating lipid level  (IAGP)
abnormal CNS synaptic transmission  (IAGP)
abnormal conditioned taste aversion behavior  (IAGP)
abnormal diestrus  (IAGP)
abnormal digestive system physiology  (IAGP)
abnormal eating behavior  (IAGP)
abnormal embryo implantation  (IAGP)
abnormal endometrium morphology  (IAGP)
abnormal energy expenditure  (IAGP)
abnormal enzyme/coenzyme activity  (IAGP)
abnormal epididymal fat pad morphology  (IAGP)
abnormal estrous cycle  (IEA)
abnormal exocrine pancreas morphology  (IAGP)
abnormal eye electrophysiology  (IAGP)
abnormal fat pad morphology  (IAGP)
abnormal female reproductive system morphology  (IAGP)
abnormal food intake  (IAGP)
abnormal functional residual capacity  (IAGP)
abnormal gait  (IEA)
abnormal gluconeogenesis  (IAGP)
abnormal glucose homeostasis  (IAGP)
abnormal gonadal fat pad morphology  (IAGP)
abnormal hematopoietic system morphology/development  (IAGP)
abnormal hormone level  (IAGP)
abnormal hypothalamus physiology  (IAGP)
abnormal inhibitory postsynaptic currents  (IAGP)
abnormal insulin secretion  (IAGP)
abnormal interleukin level  (IAGP)
abnormal intestinal epithelium morphology  (IAGP)
abnormal intraocular pressure  (IAGP)
abnormal kidney afferent arteriole morphology  (IAGP)
abnormal kidney calyx morphology  (IAGP)
abnormal kidney morphology  (IAGP)
abnormal kidney papilla morphology  (IAGP)
abnormal lactation  (IAGP)
abnormal learning/memory/conditioning  (IAGP)
abnormal leukocyte morphology  (IAGP)
abnormal lipid level  (IAGP)
abnormal locomotor activation  (IAGP)
abnormal locomotor behavior  (IEA)
abnormal locomotor circadian rhythm  (IAGP)
abnormal lung compliance  (IAGP)
abnormal mesenteric fat pad morphology  (IAGP)
abnormal metestrus  (IAGP)
abnormal mitochondrial physiology  (IAGP)
abnormal myelin sheath morphology  (IAGP)
abnormal myocardial fiber morphology  (IAGP)
abnormal myocardium layer morphology  (IAGP)
abnormal nephron morphology  (IAGP)
abnormal nerve conduction  (IAGP)
abnormal nervous system electrophysiology  (IAGP)
abnormal nervous system morphology  (IAGP)
abnormal neuron physiology  (IAGP)
abnormal nucleotide metabolism  (IAGP)
abnormal osteoclast differentiation  (IAGP)
abnormal oxygen consumption  (IAGP)
abnormal pancreas physiology  (IAGP)
abnormal pancreatic beta cell morphology  (IAGP)
abnormal pancreatic beta cell physiology  (IAGP)
abnormal pancreatic islet cell apoptosis  (IAGP)
abnormal pancreatic islet morphology  (IAGP)
abnormal parturition  (IAGP)
abnormal pelvic girdle bone morphology  (IEA)
abnormal peptide metabolism  (IAGP)
abnormal percent body fat/body weight  (IAGP)
abnormal podocyte morphology  (IAGP)
abnormal renal fat pad morphology  (IAGP)
abnormal renal glomerulus morphology  (IAGP)
abnormal respiratory electron transport chain  (IAGP)
abnormal respiratory mechanics  (IAGP)
abnormal response to cardiac infarction  (IAGP)
abnormal response/metabolism to endogenous compounds  (IAGP)
abnormal retina morphology  (IAGP)
abnormal retina vasculature morphology  (IAGP)
abnormal skeleton development  (IAGP)
abnormal spatial learning  (IAGP)
abnormal spatial reference memory  (IAGP)
abnormal sympathetic nervous system physiology  (IAGP)
abnormal synaptic dopamine release  (IAGP)
abnormal urine protein level  (IAGP)
abnormal uterus morphology  (IAGP)
abnormal vascular development  (IAGP)
abnormal vascular wound healing  (IAGP)
abnormal white adipose tissue morphology  (IAGP)
absent adrenal medulla  (IEA)
absent corpus luteum  (IAGP)
absent estrous cycle  (IAGP)
absent estrus  (IAGP)
absent long-term depression  (IAGP)
absent mature ovarian follicles  (IAGP)
adipose tissue inflammation  (IAGP)
albuminuria  (IAGP)
amyloidosis  (IAGP)
anovulation  (IAGP)
cardiac ischemia  (IAGP)
constricted vagina orifice  (IAGP)
decreased abdominal adipose tissue amount  (IAGP)
decreased body fat mass  (IAGP)
decreased body length  (IAGP)
decreased body size  (IAGP)
decreased body temperature  (IAGP)
decreased body weight  (IAGP)
decreased bone marrow cell number  (IAGP)
decreased bone mineral content  (IEA)
decreased bone mineral density  (IEA)
decreased carbon dioxide production  (IAGP)
decreased cardiac muscle contractility  (IAGP)
decreased cardiac output  (IAGP)
decreased CD4-positive, alpha-beta T cell number  (IAGP)
decreased CD8-positive, naive alpha-beta T cell number  (IEA)
decreased cell death  (IEA)
decreased circulating adiponectin level  (IAGP)
decreased circulating adrenaline level  (IAGP)
decreased circulating chloride level  (IEA)
decreased circulating cholesterol level  (IAGP)
decreased circulating glucose level  (IAGP)
decreased circulating growth hormone level  (IAGP)
decreased circulating insulin level  (IAGP)
decreased circulating leptin level  (IAGP)
decreased circulating noradrenaline level  (IAGP)
decreased circulating thyroxine level  (IAGP)
decreased circulating triglyceride level  (IAGP)
decreased core body temperature  (IAGP)
decreased corpora lutea number  (IEA)
decreased energy expenditure  (IAGP)
decreased exploration in new environment  (IEA)
decreased follicle stimulating hormone level  (IAGP)
decreased gonadal fat pad weight  (IAGP)
decreased heart rate  (IAGP)
decreased heart weight  (IEA)
decreased hematopoietic cell number  (IAGP)
decreased insulin secretion  (IAGP)
decreased lean body mass  (IAGP)
decreased leukocyte cell number  (IAGP)
decreased litter size  (IAGP)
decreased liver triglyceride level  (IAGP)
decreased locomotor activity  (IAGP)
decreased lymphocyte cell number  (IEA)
decreased mature ovarian follicle number  (IEA)
decreased motor neuron number  (IAGP)
decreased muscle weight  (IAGP)
decreased oocyte number  (IEA)
decreased ovulation rate  (IAGP)
decreased oxygen consumption  (IAGP)
decreased prostaglandin level  (IAGP)
decreased pulmonary ventilation  (IAGP)
decreased renal glomerular filtration rate  (IAGP)
decreased respiratory quotient  (IAGP)
decreased response to antigen  (IEA)
decreased somatotroph cell number  (IAGP)
decreased spleen weight  (IEA)
decreased splenocyte number  (IAGP)
decreased susceptibility to age related obesity  (IAGP)
decreased systemic arterial blood pressure  (IAGP)
decreased systemic arterial systolic blood pressure  (IAGP)
decreased T cell proliferation  (IAGP)
decreased total body fat amount  (IAGP)
decreased urine albumin level  (IAGP)
decreased uterus weight  (IAGP)
decreased white fat cell size  (IAGP)
degranulated pancreatic beta cells  (IAGP)
delayed estrous cycle  (IAGP)
delayed estrus  (IAGP)
delayed parturition  (IAGP)
delayed wound healing  (IAGP)
dystocia  (IAGP)
enlarged adrenal glands  (IEA)
enlarged kidney  (IAGP)
enlarged liver  (IAGP)
enlarged placenta  (IAGP)
enlarged spleen  (IAGP)
expanded mesangial matrix  (IAGP)
extended life span  (IAGP)
extramedullary hematopoiesis  (IAGP)
female infertility  (IAGP)
glomerulosclerosis  (IAGP)
heart left ventricle hypertrophy  (IAGP)
hepatic steatosis  (IAGP)
homeostasis/metabolism phenotype  (IAGP)
hyperactivity  (IAGP)
hyperglycemia  (IAGP)
hyperlipidemia  (IAGP)
hypoglycemia  (IAGP)
impaired adaptive thermogenesis  (IAGP)
impaired balance  (IEA)
impaired coordination  (IEA)
impaired glucose tolerance  (IAGP)
impaired righting response  (IEA)
improved glucose tolerance  (IAGP)
increased abdominal adipose tissue amount  (IAGP)
increased anxiety-related response  (IEA)
increased birth weight  (IAGP)
increased blood urea nitrogen level  (IAGP)
increased blood uric acid level  (IAGP)
increased body fat mass  (IAGP)
increased body length  (IAGP)
increased body size  (IAGP)
increased body weight  (IAGP)
increased bone volume  (IAGP)
increased brown adipose tissue amount  (IAGP)
increased carbon dioxide production  (IAGP)
increased cholesterol level  (IAGP)
increased circulating alanine transaminase level  (IEA)
increased circulating alkaline phosphatase level  (IEA)
increased circulating amylase level  (IEA)
increased circulating aspartate transaminase level  (IEA)
increased circulating calcium level  (IEA)
increased circulating cholesterol level  (IAGP)
increased circulating corticosterone level  (IAGP)
increased circulating creatinine level  (IAGP)
increased circulating free fatty acids level  (IAGP)
increased circulating fructosamine level  (IEA)
increased circulating glucagon level  (IAGP)
increased circulating glucose level  (IAGP)
increased circulating glycerol level  (IAGP)
increased circulating HDL cholesterol level  (IAGP)
increased circulating insulin level  (IAGP)
increased circulating interleukin-6 level  (IAGP)
increased circulating iron level  (IEA)
increased circulating ketone body level  (IAGP)
increased circulating LDL cholesterol level  (IAGP)
increased circulating leptin level  (IAGP)
increased circulating phosphate level  (IEA)
increased circulating potassium level  (IEA)
increased circulating serum albumin level  (IEA)
increased circulating testosterone level  (IAGP)
increased circulating total protein level  (IEA)
increased circulating triglyceride level  (IAGP)
increased circulating VLDL cholesterol level  (IAGP)
increased creatinine clearance  (IAGP)
increased effector memory CD4-positive, alpha-beta T cell number  (IEA)
increased effector memory CD8-positive, alpha-beta T cell number  (IEA)
increased enterocyte apoptosis  (IAGP)
increased eosinophil cell number  (IEA)
increased epididymal fat pad weight  (IAGP)
increased fasting circulating glucose level  (IAGP)
increased fat cell size  (IAGP)
increased fluid intake  (IAGP)
increased food intake  (IAGP)
increased glucagon secretion  (IAGP)
increased glycosylated hemoglobin level  (IAGP)
increased gonadal fat pad weight  (IAGP)
increased heart weight  (IAGP)
increased hematocrit  (IEA)
increased hemoglobin content  (IEA)
increased hepatocyte apoptosis  (IAGP)
increased IgE level  (IEA)
increased insulin secretion  (IAGP)
increased insulin sensitivity  (IAGP)
increased interleukin-6 secretion  (IAGP)
increased kidney weight  (IAGP)
increased lean body mass  (IAGP)
increased left ventricle diastolic pressure  (IAGP)
increased liver glycogen level  (IEA)
increased liver triglyceride level  (IAGP)
increased liver weight  (IAGP)
increased mean corpuscular hemoglobin  (IEA)
increased mean corpuscular volume  (IEA)
increased mean platelet volume  (IEA)
increased mean systemic arterial blood pressure  (IAGP)
increased mesenteric fat pad weight  (IAGP)
increased metastatic potential  (IAGP)
increased monocyte cell number  (IEA)
increased neutrophil cell number  (IAGP)
increased omental fat pad weight  (IAGP)
increased oxygen consumption  (IAGP)
increased pancreatic alpha cell number  (IAGP)
increased pancreatic beta cell mass  (IAGP)
increased pancreatic beta cell number  (IAGP)
increased pancreatic islet cell apoptosis  (IAGP)
increased percent body fat/body weight  (IAGP)
increased red blood cell distribution width  (IEA)
increased renal glomerulus apoptosis  (IAGP)
increased renal glomerulus basement membrane thickness  (IAGP)
increased respiratory quotient  (IAGP)
increased subcutaneous adipose tissue amount  (IAGP)
increased susceptibility to age related obesity  (IAGP)
increased susceptibility to autoimmune diabetes  (IAGP)
increased susceptibility to diet-induced hepatic steatosis  (IAGP)
increased susceptibility to diet-induced non-insulin dependent diabetes  (IAGP)
increased susceptibility to diet-induced obesity  (IAGP)
increased susceptibility to endotoxin shock  (IAGP)
increased susceptibility to induced morbidity/mortality  (IAGP)
increased susceptibility to non-insulin-dependent diabetes  (IAGP)
increased susceptibility to parasitic infection  (IAGP)
increased susceptibility to weight gain  (IAGP)
increased systemic arterial systolic blood pressure  (IAGP)
increased total body fat amount  (IAGP)
increased urine glucose level  (IAGP)
increased urine protein level  (IAGP)
increased vasoconstriction  (IAGP)
increased white fat cell size  (IAGP)
infertility  (IAGP)
insulin resistance  (IAGP)
lethality, incomplete penetrance  (IAGP)
limb grasping  (IEA)
liver fibrosis  (IAGP)
liver inflammation  (IAGP)
lung inflammation  (IAGP)
macrovesicular hepatic steatosis  (IAGP)
male infertility  (IAGP)
maternal effect  (IAGP)
mesangiolysis  (IAGP)
microvesicular hepatic steatosis  (IAGP)
no abnormal phenotype detected  (IAGP)
obese  (IAGP)
ovary inflammation  (IAGP)
oxidative stress  (IAGP)
pancreas inflammation  (IAGP)
pancreatic islet hyperplasia  (IAGP)
periinsulitis  (IAGP)
polydipsia  (IAGP)
polyphagia  (IAGP)
polyuria  (IAGP)
premature death  (IAGP)
pup cannibalization  (IAGP)
reduced female fertility  (IAGP)
reduced long-term potentiation  (IAGP)
reduced male fertility  (IEA)
reduced male mating frequency  (IAGP)
renal glomerular immunoglobulin deposits  (IAGP)
renal glomerular protein deposits  (IAGP)
renal glomerulus fibrosis  (IAGP)
renal glomerulus lipidosis  (IAGP)
short femur  (IAGP)
short tail  (IAGP)
short tibia  (IEA)
small male preputial gland  (IAGP)
small seminal vesicle  (IEA)
small uterus  (IAGP)
spleen hyperplasia  (IAGP)
thrombocytopenia  (IEA)
tremors  (IEA)
trunk curl  (IEA)
weight loss  (IAGP)
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PMID:36012573   PMID:36030260   PMID:36050503   PMID:36058294   PMID:36059948   PMID:36083102   PMID:36091357   PMID:36104081   PMID:36104373   PMID:36142408   PMID:36147472   PMID:36152407  
PMID:36159784   PMID:36198696   PMID:36213297   PMID:36232770   PMID:36240146   PMID:36243006   PMID:36266275   PMID:36272977   PMID:36302455   PMID:36325440   PMID:36347273   PMID:36361612  
PMID:36361652   PMID:36383351   PMID:36416174   PMID:36423694   PMID:36446229   PMID:36448459   PMID:36481371   PMID:36497087   PMID:36505926   PMID:36506555   PMID:36512408   PMID:36568118  
PMID:36577075   PMID:36593271   PMID:36607794   PMID:36634673   PMID:36639674   PMID:36674854   PMID:36683455   PMID:36697822   PMID:36713846   PMID:36717247   PMID:36727569   PMID:36732513  
PMID:36742073   PMID:36753399   PMID:36774552   PMID:36822326   PMID:36827985   PMID:36854759   PMID:36859576   PMID:36868235   PMID:36874012   PMID:36889283   PMID:36891264   PMID:36892073  
PMID:36901964   PMID:36912597   PMID:36921531   PMID:37035668   PMID:37037837   PMID:37047807   PMID:37048134   PMID:37062410   PMID:37097749   PMID:37116488   PMID:37123234   PMID:37124755  
PMID:37168577   PMID:37175628   PMID:37185464   PMID:37202506   PMID:37208852   PMID:37216518   PMID:37217565   PMID:37224018   PMID:37272212   PMID:37279395   PMID:37314160   PMID:37331680  
PMID:37337031   PMID:37401647   PMID:37402735   PMID:37421924   PMID:37433299   PMID:37433344   PMID:37435939   PMID:37454871   PMID:37458434   PMID:37468098   PMID:37482199   PMID:37488474  
PMID:37511155   PMID:37524876   PMID:37541251   PMID:37562743   PMID:37569859   PMID:37611830   PMID:37624889   PMID:37731032   PMID:37762509   PMID:37783236   PMID:37791586   PMID:37834032  
PMID:37850099   PMID:37863964   PMID:37871012   PMID:37895057   PMID:37952690   PMID:38071217   PMID:38091996   PMID:38141610   PMID:38145825   PMID:38147550   PMID:38164169   PMID:38251917  
PMID:38362276  


Genomics

Comparative Map Data
Lepr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394101,574,393 - 101,676,375 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4101,574,601 - 101,672,549 (+)EnsemblGRCm39 Ensembl
GRCm384101,717,137 - 101,815,352 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4101,717,404 - 101,815,352 (+)EnsemblGRCm38mm10GRCm38
MGSCv374101,390,012 - 101,487,959 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364101,215,371 - 101,313,237 (+)NCBIMGSCv36mm8
Celera4100,061,452 - 100,155,523 (+)NCBICelera
Cytogenetic Map4C6NCBI
cM Map446.96NCBI
LEPR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38165,420,652 - 65,641,559 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl165,420,652 - 65,641,559 (+)EnsemblGRCh38hg38GRCh38
GRCh37165,886,335 - 66,107,242 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36165,658,906 - 65,875,410 (+)NCBINCBI36Build 36hg18NCBI36
Build 34165,598,338 - 65,814,843NCBI
Celera164,176,916 - 64,393,787 (+)NCBICelera
Cytogenetic Map1p31.3NCBI
HuRef163,995,123 - 64,212,195 (+)NCBIHuRef
CHM1_1166,002,606 - 66,219,234 (+)NCBICHM1_1
T2T-CHM13v2.0165,298,629 - 65,519,352 (+)NCBIT2T-CHM13v2.0
Lepr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85121,409,735 - 121,593,201 (+)NCBIGRCr8
mRatBN7.25116,294,409 - 116,477,904 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5116,289,823 - 116,475,908 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5118,847,763 - 119,019,098 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05120,573,106 - 120,744,441 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05120,624,429 - 120,795,760 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05120,503,475 - 120,682,281 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5120,564,645 - 120,682,221 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05124,380,327 - 124,525,200 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.05124,555,678 - 124,556,585 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45122,320,075 - 122,503,449NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5114,817,255 - 114,982,861 (+)NCBICelera
RH 3.4 Map5 RGD
Cytogenetic Map5q33NCBI
Lepr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542325,111,266 - 25,185,407 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542325,108,897 - 25,185,315 (-)NCBIChiLan1.0ChiLan1.0
LEPR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21161,226,191 - 161,441,177 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11160,386,446 - 160,592,001 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0164,772,612 - 64,881,886 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1166,651,994 - 66,764,768 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl166,693,926 - 66,764,768 (+)Ensemblpanpan1.1panPan2
LEPR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1544,684,118 - 44,775,626 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl544,688,109 - 44,775,636 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha544,745,719 - 44,810,649 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0544,870,825 - 44,963,640 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl544,875,468 - 44,963,183 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1544,840,852 - 44,906,048 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0544,786,008 - 44,851,055 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0545,029,763 - 45,094,688 (-)NCBIUU_Cfam_GSD_1.0
Lepr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505878,634,973 - 78,718,201 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365915,774,326 - 5,836,444 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365915,771,371 - 5,846,177 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LEPR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6146,801,954 - 146,895,995 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16146,802,297 - 146,896,152 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LEPR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12067,454,205 - 67,567,524 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2067,454,334 - 67,524,229 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603349,988,602 - 50,125,048 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lepr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474229,223,392 - 29,337,049 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474229,221,742 - 29,313,273 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Lepr
3937 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2172
Count of miRNA genes:783
Interacting mature miRNAs:1010
Transcripts:ENSMUST00000037552, ENSMUST00000102777, ENSMUST00000106921, ENSMUST00000128948, ENSMUST00000145024, ENSMUST00000151733, ENSMUST00000156402
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117072206Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000128993793Mouse
27226724Tibw2_mtibia width 2, proximal, 10 week (mouse)443000000108357197Mouse
1558948Ath8_matherosclerosis 8 (mouse)Not determined445658442105156995Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138342753Mouse
1300966Pabr2_mplasma apolipoprotein B (human) regulator 2 (mouse)Not determined446332646105801860Mouse
11532714Sluc43_msusceptibility to lung cancer 43 (mouse)446642108123127211Mouse
4141900Skts-fp1_mskin tumor susceptibility in FVB and PWK 1 (mouse)Not determined453550839124055180Mouse
26884434Zlq1_mzygomatic length QTL 1, 5 week (mouse)453700000103257197Mouse
27095905Scvln3_msacral vertebrae length 2, 5 week (mouse)455600000128993793Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
27095939Ulnl9_mulna length 9, 16 week (mouse)465318237118857197Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465718237146584457Mouse
27095900Scvln9_msacral vertebrae length 2, 10 week (mouse)468018237107157197Mouse
27095917Scvln14_msacral vertebrae length 2, 16 week (mouse)468018237130277062Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468018237150884457Mouse
27095924Pglq2_mpelvic girdle length QTL 2, 5 week (mouse)469118237130727311Mouse
1302057Pgia27_mproteoglycan induced arthritis 27 (mouse)Not determined470067227104067464Mouse
12879897Berr4_mberghei resistance locus 4 (mouse)471982069105982216Mouse
1302044Nss1_mNOD Sjogren's syndrome 1 (mouse)Not determined471982069105982216Mouse
1301739Pitm2_mprion incubation time 2 (mouse)Not determined471982069105982216Mouse
1302031Bulb1_mbulb size 1 (mouse)Not determined474033887108034029Mouse
1301597Anxty_manxiety (mouse)Not determined474137574128009280Mouse
10412193Plep_mplasma lepin levels (mouse)Not determined474444699108444983Mouse
11532700Sluc43d_msusceptibility to lung cancer 43d (mouse)474444699108444983Mouse
11532701Sluc43e_msusceptibility to lung cancer 43e (mouse)474444699108444983Mouse
11532702Sluc43f_msusceptibility to lung cancer 43f (mouse)474444699108444983Mouse
11532703Sluc43g_msusceptibility to lung cancer 43g (mouse)474444699108444983Mouse
11532704Sluc43a_msusceptibility to lung cancer 43a (mouse)474444699108444983Mouse
11532705Sluc43b_msusceptibility to lung cancer 43b (mouse)474444699108444983Mouse
11532706Sluc43c_msusceptibility to lung cancer 43c (mouse)474444699108444983Mouse
11532707Sluc43h_msusceptibility to lung cancer 43h (mouse)474444699108444983Mouse
11532708Sluc43i_msusceptibility to lung cancer 43i (mouse)474444699108444983Mouse
26884431Zlq8_mzygomatic length QTL 8, 16 week (mouse)474718237108357197Mouse
1301545Gauc_mglucose area under curve (mouse)Not determined476763107110763305Mouse
1300697Sle2_msystemic lupus erythmatosus susceptibility 2 (mouse)Not determined477957579111957775Mouse
11039504Ltpr4a_mLeishmania tropica response 4a (mouse)479365751113365867Mouse
11039505Ltpr4c_mLeishmania tropica response 4c (mouse)479365751113365867Mouse
11039506Ltpr4b_mLeishmania tropica response 4b (mouse)479365751113365867Mouse
11039517Ltpr4_mLeishmania tropica response 4 (mouse)479365751113365867Mouse
12904933Edlmmq3_mextensor digitorum longus muscle mass QTL 3 (mouse)481213991115213991Mouse
1302204Spm1_msplenomegaly modifier (mouse)Not determined482244395116244582Mouse
27095921Pglq12_mpelvic girdle length QTL 12, 16 week (mouse)483118237108357197Mouse
1301867Idd11_minsulin dependent diabetes susceptibility 11 (mouse)Not determined483604870117605006Mouse
27226787Feml14_mfemur length 14, 10 week (mouse)484918237107157197Mouse
26884435Zlq4_mzygomatic length QTL 4, 10 week (mouse)485118237104957197Mouse
1357726Lnopy1_mlens opacity 1 (mouse)Not determined485428838119429037Mouse
1301556Cd4vts1_mCD4 virgin T cell subset 1 (mouse)Not determined485428838119429037Mouse
1301930Papg1_mpulmonary adenoma progression 1 (mouse)Not determined485781167119781279Mouse
1301118Bbaa23_mB.burgdorferi-associated arthritis 23 (mouse)Not determined485781167119781279Mouse
27226801Feml6_mfemur length 6, 5 week (mouse)487518237103257197Mouse
27226746Metcl8_mmetatarsal-calcaneal length 8, 10 week (mouse)487518237107157197Mouse
27226739Metcl14_mmetatarsal-calcaneal length 14, 16 week (mouse)487518237108357197Mouse
27095927Pglq7_mpelvic girdle length QTL 7, 10 week (mouse)488118237108357197Mouse
27226716Metcl2_mmetatarsal-calcaneal length 2, 5 week (mouse)488118237118557197Mouse
27226770Tibl11_mtibia length 11, 10 week (mouse)488518237108357197Mouse
27226766Tibl17_mtibia length 17, 16 week (mouse)488518237108457197Mouse
11532738Abd1_mautoimmune biliary disease 1 (mouse)488982069116271120Mouse
4141623W6q13_mweight 6 weeks QTL 13 (mouse)Not determined88982069140468203Mouse
4141549W10q10_mweight 10 weeks QTL 10 (mouse)Not determined88982069140468203Mouse
4141093W3q17_mweight 3 weeks QTL 17 (mouse)Not determined88982069140468203Mouse
39128212Lwq21_mliver weight QTL 21 (mouse)488982069140468203Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined488982069151654550Mouse
13824982Svwq1_mseminal vesicle weight QTL 1 (mouse)489888237118857197Mouse
1300918Stheal4_msoft tissue heal 4 (mouse)Not determined489969627123969747Mouse
11553870Cmmm_mcarcinoma modifier of MSM (mouse)490590668124590781Mouse
15039368Nmrs19_mNAFLD-associated magnetic resonance shift 19 (mouse)490882780124882780Mouse
27226760Feml19_mfemur length 19, 16 week (mouse)490888237108457197Mouse
27226782Tibl2_mtibia length 2, 5 week (mouse)490888237111257197Mouse
13208562Wght7_mweight 7 (mouse)490888237148084457Mouse
12904002Opfaq9_mopen field activity QTL 9 (mouse)492975790126975790Mouse
1301731Cafq2_mcaffeine metabolism QTL 2 (mouse)Not determined494732255128732454Mouse
1301233Sbw2_msplenomegaly-NZB x NZW 2 (mouse)Not determined494957579128009280Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined494957579150676858Mouse
14696687Gdq1_mgrooming duration QTL 1, males (mouse)496888237111857197Mouse
1300580Lbw2_mlupus NZB x NZW 2 (mouse)Not determined498545539128009280Mouse
1301106Skts7_mskin tumor susceptibility 7 (mouse)Not determined4100071971134072206Mouse
1301847Fecq2_mfecundity QTL 2 (mouse)Not determined4100071971134072206Mouse
14696689Gdq2_mgrooming duration QTL 2, females (mouse)4100857197124893793Mouse
12880433Fgf23lq1_mFGF23 serum level QTL 1 (mouse)4101157197135157197Mouse
1300689Dob1_mDietary obesity 1 (mouse)Body weight4101574601123127211Mouse

Markers in Region
BE687169  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384101,813,501 - 101,813,607UniSTSGRCm38
MGSCv374101,486,106 - 101,486,212UniSTSGRCm37
Celera4100,153,670 - 100,153,776UniSTS
Cytogenetic Map4C6UniSTS
cM Map446.7UniSTS
Whitehead/MRC_RH41414.06UniSTS
U52915  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384101,792,155 - 101,792,257UniSTSGRCm38
MGSCv374101,464,760 - 101,464,862UniSTSGRCm37
Celera4100,132,338 - 100,132,440UniSTS
Cytogenetic Map4C6UniSTS
cM Map446.7UniSTS
Whitehead_YAC4 UniSTS
D9Mit34.1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7F1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map2C1.3UniSTS
Cytogenetic Map19D1UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map1FUniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map3F2UniSTS
Cytogenetic Map14C3UniSTS
Cytogenetic Map9A3UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map11B4UniSTS
Cytogenetic Map5G3UniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map6F2UniSTS
Cytogenetic Map1C1.3UniSTS
Cytogenetic Map16B1UniSTS
Cytogenetic Map12C1UniSTS
Cytogenetic Map7E2UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map2E2UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map15E1UniSTS
Cytogenetic Map3G2UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map1E3UniSTS
Cytogenetic Map5E1UniSTS
Cytogenetic Map7F3UniSTS
Cytogenetic Map16B3UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map19D3UniSTS
Cytogenetic Map1H5UniSTS
Cytogenetic Map1DUniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map8A2UniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map2BUniSTS
Cytogenetic Map5A3UniSTS
Cytogenetic Map9DUniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map4C6UniSTS
Cytogenetic Map17DUniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map13A1UniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map12A3UniSTS
Cytogenetic Map1H2.1UniSTS
Cytogenetic Map7F5UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map2E1UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map5C3.3UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map5G1UniSTS
Cytogenetic Map6A2UniSTS
Cytogenetic Map7B1UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map5C3.1UniSTS
Cytogenetic Map2C3UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map11B1.1UniSTS
Cytogenetic Map1H6UniSTS
Cytogenetic Map2C2UniSTS
Cytogenetic Map19CUniSTS
Cytogenetic Map17E1.3UniSTS
Cytogenetic Map5A1UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map1A1UniSTS
Cytogenetic Map13A5UniSTS
Cytogenetic MapXA1.1UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map3A3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map8CUniSTS
Cytogenetic Map12EUniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map2H3UniSTS
Cytogenetic Map2A1UniSTS
Cytogenetic Map1H1UniSTS
Cytogenetic Map15F3UniSTS
Cytogenetic Map9E1UniSTS
Cytogenetic Map9CUniSTS
Cytogenetic Map1A2UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXC-DUniSTS
Cytogenetic Map5G1.3UniSTS
Cytogenetic Map7D1-E2UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map1H2.2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic Map11DUniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map16C1.1UniSTS
Cytogenetic Map15F2UniSTS
Cytogenetic Map9A2UniSTS
Cytogenetic Map1H4-H6UniSTS
Cytogenetic Map12D2UniSTS
Cytogenetic Map1G3UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map1H3UniSTS
Cytogenetic Map19BUniSTS
cM Map950.0UniSTS
Whitehead Genetic943.7UniSTS
PMC104257P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384101,768,070 - 101,768,222UniSTSGRCm38
MGSCv374101,440,675 - 101,440,827UniSTSGRCm37
Celera4100,106,117 - 100,106,269UniSTS
Cytogenetic Map4C6UniSTS
cM Map446.7UniSTS
PMC104257P2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384101,814,563 - 101,815,050UniSTSGRCm38
MGSCv374101,487,168 - 101,487,655UniSTSGRCm37
Celera4100,154,732 - 100,155,219UniSTS
Cytogenetic Map4C6UniSTS
cM Map446.7UniSTS
Lepr  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv374101,464,602 - 101,464,781UniSTSGRCm37
MGSCv374101,487,354 - 101,487,894UniSTSGRCm37
Celera4100,154,918 - 100,155,458UniSTS
Celera4100,132,180 - 100,132,359UniSTS
Cytogenetic Map4C6UniSTS
cM Map446.7UniSTS
cM Map446.7UniSTS
cM Map446.7UniSTS
PMC21274P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384101,814,674 - 101,814,794UniSTSGRCm38
MGSCv374101,487,279 - 101,487,399UniSTSGRCm37
Celera4100,154,843 - 100,154,963UniSTS
Cytogenetic Map4C6UniSTS
cM Map446.7UniSTS
PMC21274P2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384101,792,558 - 101,792,770UniSTSGRCm38
MGSCv374101,465,163 - 101,465,375UniSTSGRCm37
Celera4100,132,741 - 100,132,953UniSTS
Cytogenetic Map4C6UniSTS
cM Map446.7UniSTS
PMC21274P3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384101,813,825 - 101,814,720UniSTSGRCm38
MGSCv374101,486,430 - 101,487,325UniSTSGRCm37
Celera4100,153,994 - 100,154,889UniSTS
Cytogenetic Map4C6UniSTS
cM Map446.7UniSTS
LEPR-2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384101,814,554 - 101,815,056UniSTSGRCm38
MGSCv374101,487,159 - 101,487,661UniSTSGRCm37
Celera4100,154,723 - 100,155,225UniSTS
Cytogenetic Map4C6UniSTS
cM Map446.7UniSTS
Lepr  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384101,791,997 - 101,792,176UniSTSGRCm38
MGSCv374101,464,602 - 101,464,781UniSTSGRCm37
Celera4100,132,180 - 100,132,359UniSTS
Cytogenetic Map4C6UniSTS
cM Map446.7UniSTS
Lepr  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384101,814,749 - 101,815,289UniSTSGRCm38
MGSCv374101,487,354 - 101,487,894UniSTSGRCm37
Celera4100,154,918 - 100,155,458UniSTS
Cytogenetic Map4C6UniSTS
cM Map446.7UniSTS
Lepr  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4C6UniSTS
Lepr  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4C6UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001122899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_146146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036163750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036163751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036163752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB519174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB519175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB519176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB519177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB519178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF098792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF152957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH005809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK136231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK140785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK143989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL929373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC082551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ319649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN692760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U42467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U46135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U49106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U49107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U49108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U49109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U49110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U52915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U58861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U58862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U58863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U97032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U97034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y10296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y10298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000037552   ⟹   ENSMUSP00000037385
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4101,574,601 - 101,672,549 (+)Ensembl
GRCm38.p6 Ensembl4101,717,404 - 101,815,352 (+)Ensembl
RefSeq Acc Id: ENSMUST00000102777   ⟹   ENSMUSP00000099838
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4101,574,601 - 101,649,455 (+)Ensembl
GRCm38.p6 Ensembl4101,717,404 - 101,792,258 (+)Ensembl
RefSeq Acc Id: ENSMUST00000106921   ⟹   ENSMUSP00000102534
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4101,574,601 - 101,670,864 (+)Ensembl
GRCm38.p6 Ensembl4101,717,404 - 101,813,667 (+)Ensembl
RefSeq Acc Id: ENSMUST00000128948
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4101,625,244 - 101,636,790 (+)Ensembl
GRCm38.p6 Ensembl4101,768,047 - 101,779,593 (+)Ensembl
RefSeq Acc Id: ENSMUST00000145024   ⟹   ENSMUSP00000123654
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4101,574,604 - 101,590,514 (+)Ensembl
GRCm38.p6 Ensembl4101,717,407 - 101,733,317 (+)Ensembl
RefSeq Acc Id: ENSMUST00000151733
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4101,646,111 - 101,649,353 (+)Ensembl
GRCm38.p6 Ensembl4101,788,914 - 101,792,156 (+)Ensembl
RefSeq Acc Id: ENSMUST00000156402
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4101,628,565 - 101,640,092 (+)Ensembl
GRCm38.p6 Ensembl4101,771,368 - 101,782,895 (+)Ensembl
RefSeq Acc Id: NM_001122899   ⟹   NP_001116371
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394101,575,103 - 101,670,864 (+)NCBI
GRCm384101,717,906 - 101,813,667 (+)NCBI
MGSCv374101,390,012 - 101,487,959 (+)RGD
Celera4100,061,452 - 100,155,523 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_010704   ⟹   NP_034834
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394101,574,604 - 101,649,455 (+)NCBI
GRCm384101,717,407 - 101,792,258 (+)NCBI
MGSCv374101,390,012 - 101,487,959 (+)RGD
Celera4100,061,452 - 100,155,523 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_146146   ⟹   NP_666258
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394101,575,103 - 101,672,549 (+)NCBI
GRCm384101,717,906 - 101,815,352 (+)NCBI
MGSCv374101,390,012 - 101,487,959 (+)RGD
Celera4100,061,452 - 100,155,523 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036163750   ⟹   XP_036019643
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394101,574,393 - 101,676,375 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036163751   ⟹   XP_036019644
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394101,574,433 - 101,671,278 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036163752   ⟹   XP_036019645
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394101,574,430 - 101,666,866 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001116371 (Get FASTA)   NCBI Sequence Viewer  
  NP_034834 (Get FASTA)   NCBI Sequence Viewer  
  NP_666258 (Get FASTA)   NCBI Sequence Viewer  
  XP_036019643 (Get FASTA)   NCBI Sequence Viewer  
  XP_036019644 (Get FASTA)   NCBI Sequence Viewer  
  XP_036019645 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA93014 (Get FASTA)   NCBI Sequence Viewer  
  AAB95332 (Get FASTA)   NCBI Sequence Viewer  
  AAB95333 (Get FASTA)   NCBI Sequence Viewer  
  AAB95334 (Get FASTA)   NCBI Sequence Viewer  
  AAB95335 (Get FASTA)   NCBI Sequence Viewer  
  AAC52408 (Get FASTA)   NCBI Sequence Viewer  
  AAC52420 (Get FASTA)   NCBI Sequence Viewer  
  AAC52421 (Get FASTA)   NCBI Sequence Viewer  
  AAC52422 (Get FASTA)   NCBI Sequence Viewer  
  AAC52423 (Get FASTA)   NCBI Sequence Viewer  
  AAC52424 (Get FASTA)   NCBI Sequence Viewer  
  AAC52599 (Get FASTA)   NCBI Sequence Viewer  
  AAC52705 (Get FASTA)   NCBI Sequence Viewer  
  AAC52706 (Get FASTA)   NCBI Sequence Viewer  
  AAC52707 (Get FASTA)   NCBI Sequence Viewer  
  AAD13218 (Get FASTA)   NCBI Sequence Viewer  
  AAD41084 (Get FASTA)   NCBI Sequence Viewer  
  AAH82551 (Get FASTA)   NCBI Sequence Viewer  
  BAE24478 (Get FASTA)   NCBI Sequence Viewer  
  BAE25649 (Get FASTA)   NCBI Sequence Viewer  
  BAI47482 (Get FASTA)   NCBI Sequence Viewer  
  BAI47483 (Get FASTA)   NCBI Sequence Viewer  
  BAI47484 (Get FASTA)   NCBI Sequence Viewer  
  BAI47485 (Get FASTA)   NCBI Sequence Viewer  
  BAI47486 (Get FASTA)   NCBI Sequence Viewer  
  CAA71342 (Get FASTA)   NCBI Sequence Viewer  
  CAA71343 (Get FASTA)   NCBI Sequence Viewer  
  EDL30863 (Get FASTA)   NCBI Sequence Viewer  
  EDL30864 (Get FASTA)   NCBI Sequence Viewer  
  EDL30865 (Get FASTA)   NCBI Sequence Viewer  
  EDL30866 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000037385
  ENSMUSP00000037385.4
  ENSMUSP00000099838
  ENSMUSP00000099838.4
  ENSMUSP00000102534
  ENSMUSP00000102534.3
  ENSMUSP00000123654.2
GenBank Protein P48356 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_034834   ⟸   NM_010704
- Peptide Label: isoform 2 precursor
- UniProtKB: Q3UNU8 (UniProtKB/TrEMBL),   Q640Q2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_666258   ⟸   NM_146146
- Peptide Label: isoform 1 precursor
- UniProtKB: Q9QWG3 (UniProtKB/Swiss-Prot),   Q64309 (UniProtKB/Swiss-Prot),   Q61215 (UniProtKB/Swiss-Prot),   O54986 (UniProtKB/Swiss-Prot),   O35686 (UniProtKB/Swiss-Prot),   Q9QWV5 (UniProtKB/Swiss-Prot),   P48356 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001116371   ⟸   NM_001122899
- Peptide Label: isoform 3 precursor
- UniProtKB: Q3US58 (UniProtKB/TrEMBL),   Q640Q2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000123654   ⟸   ENSMUST00000145024
RefSeq Acc Id: ENSMUSP00000102534   ⟸   ENSMUST00000106921
RefSeq Acc Id: ENSMUSP00000037385   ⟸   ENSMUST00000037552
RefSeq Acc Id: ENSMUSP00000099838   ⟸   ENSMUST00000102777
RefSeq Acc Id: XP_036019643   ⟸   XM_036163750
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036019645   ⟸   XM_036163752
- Peptide Label: isoform X3
- UniProtKB: Q640Q2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036019644   ⟸   XM_036163751
- Peptide Label: isoform X2
- UniProtKB: Q640Q2 (UniProtKB/TrEMBL)
Protein Domains
Fibronectin type-III   Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P48356-F1-model_v2 AlphaFold P48356 1-1162 view protein structure

Promoters
RGD ID:6835566
Promoter ID:MM_KWN:38667
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:ENSMUST00000084387,   OTTMUST00000019183,   OTTMUST00000019184,   OTTMUST00000019185,   OTTMUST00000019186,   OTTMUST00000019187,   UC008TVX.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364101,389,821 - 101,390,321 (+)MPROMDB
RGD ID:6883978
Promoter ID:EPDNEW_M5440
Type:initiation region
Name:Lepr_2
Description:Mus musculus leptin receptor , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M5441  EPDNEW_M5442  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384101,717,430 - 101,717,490EPDNEW
RGD ID:6883980
Promoter ID:EPDNEW_M5441
Type:multiple initiation site
Name:Lepr_1
Description:Mus musculus leptin receptor , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M5440  EPDNEW_M5442  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384101,717,906 - 101,717,966EPDNEW
RGD ID:6883982
Promoter ID:EPDNEW_M5442
Type:multiple initiation site
Name:Lepr_3
Description:Mus musculus leptin receptor , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M5440  EPDNEW_M5441  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384101,727,942 - 101,728,002EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:104993 AgrOrtholog
Ensembl Genes ENSMUSG00000057722 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000037552 ENTREZGENE
  ENSMUST00000037552.10 UniProtKB/Swiss-Prot
  ENSMUST00000102777 ENTREZGENE
  ENSMUST00000102777.10 UniProtKB/Swiss-Prot
  ENSMUST00000106921 ENTREZGENE
  ENSMUST00000106921.9 UniProtKB/Swiss-Prot
  ENSMUST00000145024.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hematopoietin_rcpt_Gp130_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hempt_rcpt_S_F1_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IgC2-like_lig-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LEP-R_IGD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16847 UniProtKB/Swiss-Prot
MGD MGI:104993 ENTREZGENE
NCBI Gene 16847 ENTREZGENE
PANTHER CYTOKINE RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot
  PTHR23037:SF35 UniProtKB/TrEMBL
Pfam Lep_receptor_Ig UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ObR_Ig UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB LEPR RGD
PhenoGen Lepr PhenoGen
PROSITE FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HEMATOPO_REC_L_F2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HEMATOPO_REC_S_F1 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49265 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2AV66_MOUSE UniProtKB/TrEMBL
  D0FZQ3_MOUSE UniProtKB/TrEMBL
  LEPR_MOUSE UniProtKB/Swiss-Prot
  O35686 ENTREZGENE
  O54986 ENTREZGENE
  P48356 ENTREZGENE
  Q3UNU8 ENTREZGENE, UniProtKB/TrEMBL
  Q3US58 ENTREZGENE, UniProtKB/TrEMBL
  Q61215 ENTREZGENE
  Q640Q2 ENTREZGENE, UniProtKB/TrEMBL
  Q64309 ENTREZGENE
  Q9QWG3 ENTREZGENE
  Q9QWV5 ENTREZGENE
  Q9WV88_MOUSE UniProtKB/TrEMBL
UniProt Secondary O35686 UniProtKB/Swiss-Prot
  O54986 UniProtKB/Swiss-Prot
  Q61215 UniProtKB/Swiss-Prot
  Q64309 UniProtKB/Swiss-Prot
  Q9QWG3 UniProtKB/Swiss-Prot
  Q9QWV5 UniProtKB/Swiss-Prot