GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Lepr | increases expression | EXP | | 6480464 | CTD | Ethinyl Estradiol results in increased expression of LEPR mRNA | PMID:17942748 PMID:29112739 | Lepr | multiple interactions | EXP | | 6480464 | CTD | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LEPR mRNA; ESR1 gene mutant form inhibits the reaction [Ethinyl Estradiol results in increased expression of LEPR mRNA] | PMID:17942748 PMID:29112739 | Lepr | affects expression | ISO | Lepr (Rattus norvegicus) | 6480464 | CTD | Ethinyl Estradiol affects the expression of LEPR mRNA | PMID:26865667 | Lepr | decreases expression | ISO | Lepr (Rattus norvegicus) | 6480464 | CTD | Ethinyl Estradiol results in decreased expression of LEPR mRNA | PMID:17351261 | |
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