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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10865
Species: Mus musculus
RGD Object: Gene
Symbol: Lepr
Name: leptin receptor
Acc ID: CHEBI:79736
Term: ziram
Definition: A dithiocarbamate salt that is the zinc salt of dimethyldithiocarbamic acid. It is a broad-spectrum fungicide and bird and animal repellent that is also used to accelerate the vulcanisation of rubber.
Chemical ID: MESH:D015039
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Leprmultiple interactionsISOLepr (Rattus norvegicus)6480464CTD[2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in decreased expression of LEPR mRNAPMID:29321614
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