TAP1 (transporter 1, ATP binding cassette subfamily B member) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: TAP1 (transporter 1, ATP binding cassette subfamily B member) Sus scrofa
Analyze
Symbol: TAP1
Name: transporter 1, ATP binding cassette subfamily B member
RGD ID: 14057022
Description: ENCODES a protein that exhibits ADP binding (ortholog); ATP binding (ortholog); ATP hydrolysis activity (ortholog); INVOLVED IN defense response (ortholog); peptide transport (ortholog); protection from natural killer cell mediated cytotoxicity (ortholog); ASSOCIATED WITH allergic disease (ortholog); ankylosing spondylitis (ortholog); asthma (ortholog); FOUND IN TAP complex (ortholog); INTERACTS WITH Estradiol 17beta-cyclopentylpropionate
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: antigen peptide transporter 1; putative ABC-transporter; TAP; transporter 1, ATP-binding cassette, sub-family B (MDR/TAP); transporter associated with antigen processing 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl725,062,771 - 25,074,843 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1725,062,772 - 25,071,989 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2729,274,670 - 29,283,290 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:14681463   PMID:16555068   PMID:17145712   PMID:22211104   PMID:22301074   PMID:24854449   PMID:24955792   PMID:26169022   PMID:30032202   PMID:30950765  


Genomics

Comparative Map Data
TAP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl725,062,771 - 25,074,843 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1725,062,772 - 25,071,989 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2729,274,670 - 29,283,290 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TAP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38632,845,209 - 32,853,704 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl632,845,209 - 32,853,816 (-)EnsemblGRCh38hg38GRCh38
GRCh37632,812,986 - 32,821,481 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36632,920,964 - 32,929,726 (-)NCBINCBI36Build 36hg18NCBI36
Build 34632,920,964 - 32,929,726NCBI
Celera634,361,879 - 34,370,641 (-)NCBICelera
Cytogenetic Map6p21.32NCBI
HuRef632,555,192 - 32,563,954 (-)NCBIHuRef
CHM1_1632,813,813 - 32,822,573 (-)NCBICHM1_1
T2T-CHM13v2.0632,666,584 - 32,675,079 (-)NCBIT2T-CHM13v2.0
Tap1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,406,530 - 34,416,199 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1734,406,527 - 34,416,199 (+)EnsemblGRCm39 Ensembl
GRCm381734,187,556 - 34,197,225 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,187,553 - 34,197,225 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,324,501 - 34,334,170 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361733,798,168 - 33,807,011 (+)NCBIMGSCv36mm8
Celera1736,941,149 - 36,950,813 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
Tap1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8204,658,171 - 4,668,543 (-)NCBIGRCr8
mRatBN7.2204,656,262 - 4,666,634 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl204,656,263 - 4,666,901 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx205,408,978 - 5,419,351 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0204,770,721 - 4,781,094 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0205,252,375 - 5,262,585 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0203,979,302 - 3,989,669 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl203,979,035 - 3,989,669 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,058,850 - 6,069,217 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,790,363 - 4,800,730 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1204,791,029 - 4,800,898 (-)NCBI
Celera206,257,317 - 6,267,656 (-)NCBICelera
RH 3.4 Map2060.6RGD
Cytogenetic Map20p12NCBI
Tap1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554371,504,947 - 1,511,097 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554371,504,549 - 1,511,110 (-)NCBIChiLan1.0ChiLan1.0
TAP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2547,320,282 - 47,329,198 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1643,191,833 - 43,200,750 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0632,414,665 - 32,423,488 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1633,530,170 - 33,538,978 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl633,530,171 - 33,538,978 (-)Ensemblpanpan1.1panPan2
TAP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1122,424,049 - 2,432,165 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl122,378,126 - 2,432,303 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha122,505,714 - 2,513,929 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0122,705,692 - 2,714,297 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl122,701,094 - 2,714,024 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1122,423,131 - 2,431,320 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0122,504,597 - 2,512,789 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0122,578,932 - 2,587,126 (-)NCBIUU_Cfam_GSD_1.0
Tap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494638,052,572 - 38,060,923 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647625,899,339 - 25,907,695 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647625,899,514 - 25,907,690 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TAP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11739,252,000 - 39,260,195 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604432,632,142 - 32,640,337 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tap1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475423,815,915 - 23,822,827 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475423,815,464 - 23,822,480 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TAP1
162 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 8 2 5 2 3
Low 2 2 3 2 23 2 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001044581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021098370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF074420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK231976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK233721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK234624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK346482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK346940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK390391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK396084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK396698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU633196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ227989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ227990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GBZA01000658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GFLN01078964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSSCT00000001630   ⟹   ENSSSCP00000001588
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl725,062,773 - 25,071,862 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000082786   ⟹   ENSSSCP00000071230
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl725,062,771 - 25,074,843 (-)Ensembl
RefSeq Acc Id: NM_001044581   ⟹   NP_001038046
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1725,063,168 - 25,071,788 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021098370   ⟹   XP_020954029
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1725,062,772 - 25,071,989 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020954029   ⟸   XM_021098370
- Peptide Label: isoform X1
- UniProtKB: A0A8D1H710 (UniProtKB/TrEMBL),   Q1ACV5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001038046   ⟸   NM_001044581
- UniProtKB: Q1ACV6 (UniProtKB/TrEMBL),   A0A8D0ZVL3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000001588   ⟸   ENSSSCT00000001630
RefSeq Acc Id: ENSSSCP00000071230   ⟸   ENSSSCT00000082786
Protein Domains
ABC transmembrane type-1   ABC transporter


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000025618 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015080014 UniProtKB/TrEMBL
  ENSSSCG00025070869 UniProtKB/TrEMBL
  ENSSSCG00035045265 UniProtKB/TrEMBL
  ENSSSCG00040030747 UniProtKB/TrEMBL
  ENSSSCG00045010415 UniProtKB/TrEMBL
  ENSSSCG00050003103 UniProtKB/TrEMBL
  ENSSSCG00055009706 UniProtKB/TrEMBL
  ENSSSCG00060005116 UniProtKB/TrEMBL
  ENSSSCG00065067746 UniProtKB/TrEMBL
  ENSSSCG00070021243 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000001630 ENTREZGENE
  ENSSSCT00000001630.4 UniProtKB/TrEMBL
  ENSSSCT00000082786 ENTREZGENE
  ENSSSCT00000082786.2 UniProtKB/TrEMBL
  ENSSSCT00015109064.1 UniProtKB/TrEMBL
  ENSSSCT00015109072.1 UniProtKB/TrEMBL
  ENSSSCT00015109103.1 UniProtKB/TrEMBL
  ENSSSCT00015109131.1 UniProtKB/TrEMBL
  ENSSSCT00025097715.1 UniProtKB/TrEMBL
  ENSSSCT00025097916.1 UniProtKB/TrEMBL
  ENSSSCT00025098078.1 UniProtKB/TrEMBL
  ENSSSCT00035060452.1 UniProtKB/TrEMBL
  ENSSSCT00040041417.1 UniProtKB/TrEMBL
  ENSSSCT00040041772.1 UniProtKB/TrEMBL
  ENSSSCT00040041819.1 UniProtKB/TrEMBL
  ENSSSCT00040041846.1 UniProtKB/TrEMBL
  ENSSSCT00045017657.1 UniProtKB/TrEMBL
  ENSSSCT00045017850.1 UniProtKB/TrEMBL
  ENSSSCT00045017905.1 UniProtKB/TrEMBL
  ENSSSCT00045017961.1 UniProtKB/TrEMBL
  ENSSSCT00050004080.1 UniProtKB/TrEMBL
  ENSSSCT00050004111.1 UniProtKB/TrEMBL
  ENSSSCT00050004155.1 UniProtKB/TrEMBL
  ENSSSCT00055019308.1 UniProtKB/TrEMBL
  ENSSSCT00055019457.1 UniProtKB/TrEMBL
  ENSSSCT00055019504.1 UniProtKB/TrEMBL
  ENSSSCT00060006403.1 UniProtKB/TrEMBL
  ENSSSCT00060006410.1 UniProtKB/TrEMBL
  ENSSSCT00060006448.1 UniProtKB/TrEMBL
  ENSSSCT00065093239.1 UniProtKB/TrEMBL
  ENSSSCT00065093245.1 UniProtKB/TrEMBL
  ENSSSCT00065093259.1 UniProtKB/TrEMBL
  ENSSSCT00065093265.1 UniProtKB/TrEMBL
  ENSSSCT00070042246.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1560.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  ABC1_TM_dom UniProtKB/TrEMBL
  ABC1_TM_sf UniProtKB/TrEMBL
  ABC_Tap-like UniProtKB/TrEMBL
  ABC_transporter-like UniProtKB/TrEMBL
  ABC_transporter_CS UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Type_I_exporter UniProtKB/TrEMBL
KEGG Report ssc:733649 UniProtKB/TrEMBL
NCBI Gene TAP1 ENTREZGENE
PANTHER ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL UniProtKB/TrEMBL
  TRANSPORTER 1, ATP BINDING CASSETTE SUBFAMILY B MEMBER UniProtKB/TrEMBL
Pfam ABC_membrane UniProtKB/TrEMBL
  ABC_tran UniProtKB/TrEMBL
PIRSF ABC_prm/ATPase_B UniProtKB/TrEMBL
PRINTS TAP1PROTEIN UniProtKB/TrEMBL
PROSITE ABC_TM1F UniProtKB/TrEMBL
  ABC_TRANSPORTER_1 UniProtKB/TrEMBL
  ABC_TRANSPORTER_2 UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
  SSF90123 UniProtKB/TrEMBL
UniProt A0A4X1V406_PIG UniProtKB/TrEMBL
  A0A8D0ZVL3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1H710 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1JQ78_PIG UniProtKB/TrEMBL
  A0A8D1JU47_PIG UniProtKB/TrEMBL
  A0A8D1Q8H7_PIG UniProtKB/TrEMBL
  A5D9J3_PIG UniProtKB/TrEMBL
  F6PWU7_PIG UniProtKB/TrEMBL
  Q1ACV5 ENTREZGENE, UniProtKB/TrEMBL
  Q1ACV6 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A5G2RAR7 UniProtKB/TrEMBL
VGNC ID VGNC:98358 ENTREZGENE