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Gene: UBE2L3 (ubiquitin conjugating enzyme E2 L3) Chlorocebus sabaeus

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Symbol:

UBE2L3

Name:

ubiquitin conjugating enzyme E2 L3

RGD ID:

18707987

Description:

ENCODES a protein that exhibits transcription coactivator activity (ortholog); ubiquitin conjugating enzyme activity (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN cell cycle phase transition (ortholog); cell population proliferation (ortholog); cellular response to glucocorticoid stimulus (ortholog); PARTICIPATES IN mitochondrial autophagy pathway; ASSOCIATED WITH chromosome 22q11.2 deletion syndrome, distal (ortholog); Chronic Hepatitis B (ortholog); DiGeorge syndrome (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); presynapse (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ubiquitin-conjugating enzyme E2 L3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	19	4,485,960 - 4,538,838 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666085	2,458,762 - 2,513,218 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

chromosome 22q11.2 deletion syndrome, distal (ISO)

Chronic Hepatitis B (ISO)

DiGeorge syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell cycle phase transition (ISO)

cell population proliferation (ISO)

cellular response to glucocorticoid stimulus (ISO)

cellular response to steroid hormone stimulus (ISO)

positive regulation of protein targeting to mitochondrion (ISO)

positive regulation of protein ubiquitination (ISO)

positive regulation of ubiquitin-protein transferase activity (ISO)

protein K11-linked ubiquitination (ISO)

protein polyubiquitination (ISO)

protein ubiquitination (ISO)

regulation of DNA-templated transcription (ISO)

ubiquitin-dependent protein catabolic process (ISO)

Cellular Component

cytoplasm (ISO)

nucleus (ISO)

presynapse (ISO)

Molecular Function

protein binding (ISO)

transcription coactivator activity (ISO)

ubiquitin conjugating enzyme activity (ISO)

ubiquitin protein ligase binding (ISO)

ubiquitin-protein transferase activator activity (ISO)

ubiquitin-protein transferase activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

mitochondrial autophagy pathway (ISO)

References

Genomics

Comparative Map Data

UBE2L3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	19	4,485,960 - 4,538,838 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666085	2,458,762 - 2,513,218 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

UBE2L3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	22	21,549,447 - 21,624,034 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	22	21,549,447 - 21,624,034 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	22	21,903,736 - 21,978,323 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	22	20,251,957 - 20,308,323 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	22	20,246,510 - 20,302,877	NCBI
Celera	22	5,739,499 - 5,795,863 (+)	NCBI		Celera
Cytogenetic Map	22	q11.21	NCBI
HuRef	22	4,879,945 - 4,936,197 (+)	NCBI		HuRef
CHM1_1	22	21,904,101 - 21,978,521 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	22	21,962,924 - 22,037,518 (+)	NCBI		T2T-CHM13v2.0

Ube2l3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	16,969,879 - 17,019,363 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	16,969,877 - 17,020,513 (-)	Ensembl		GRCm39 Ensembl
GRCm38	16	17,152,015 - 17,201,512 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	17,152,013 - 17,202,649 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	17,152,108 - 17,201,585 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	17,065,578 - 17,115,055 (-)	NCBI		MGSCv36	mm8
Celera	16	17,724,819 - 17,774,277 (-)	NCBI		Celera
Cytogenetic Map	16	A3	NCBI
cM Map	16	10.63	NCBI

Ube2l3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	97,300,584 - 97,343,084 (+)	NCBI		GRCr8
mRatBN7.2	11	83,797,722 - 83,838,862 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	83,797,722 - 83,838,862 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	92,527,835 - 92,569,030 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	85,188,988 - 85,230,172 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	84,242,565 - 84,283,751 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	88,047,186 - 88,088,477 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	88,047,832 - 88,088,476 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	91,100,202 - 91,140,629 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	85,801,097 - 85,843,043 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	85,841,676 - 85,883,641 (+)	NCBI
Celera	11	82,559,953 - 82,601,068 (+)	NCBI		Celera
Cytogenetic Map	11	q23	NCBI

Ube2l3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	17,487,815 - 17,581,675 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955442	17,487,815 - 17,581,675 (-)	NCBI	ChiLan1.0	ChiLan1.0

UBE2L3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	23	31,112,684 - 31,169,247 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	22	33,661,486 - 33,717,975 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	22	3,690,100 - 3,746,665 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	22	20,174,546 - 20,229,928 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	22	20,174,546 - 20,229,928 (+)	Ensembl	panpan1.1		panPan2

UBE2L3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	30,835,222 - 30,899,842 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	30,823,209 - 30,898,324 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	30,792,988 - 30,857,171 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	32,240,509 - 32,305,707 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	32,228,421 - 32,306,279 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	30,289,976 - 30,355,037 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	29,914,008 - 29,978,785 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	31,004,051 - 31,068,673 (+)	NCBI		UU_Cfam_GSD_1.0

Ube2l3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	140,616,677 - 140,683,226 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936619	2,070,731 - 2,137,369 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936619	2,070,836 - 2,137,314 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

UBE2L3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	14	50,265,102 - 50,315,409 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	53,716,702 - 53,765,937 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Ube2l3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624747	1,125,022 - 1,177,524 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624747	1,125,009 - 1,178,595 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007974919	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007974920	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000053	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_007974919 ⟹ XP_007973110

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	19	4,485,960 - 4,538,838 (-)	NCBI
Vero_WHO_p1.0	NW_023666085	2,458,762 - 2,513,218 (+)	NCBI

Sequence:

show sequence

TCCAGGAAGTGCGGGGGCTCCAGCCGCCCGGCCGGCCGCGATGCATTCTGGGGAAGGAGCAGCA
CCAAATCCAAGATGGCGGCCAGCAGGAGGCTGATGAAGGAGCTTGAAGAAATCCGCAAATGTGG
GATGAAAAACTTCCGTAACATCCAGGTTGATGAAGCTAATTTATTGACTTGGCAAGGGCTTATT
GTTCCTGACAACCCTCCATATGATAAGGGGGCCTTCAGAATCGAAATCAACTTTCCAGCAGAGT
ACCCATTCAAACCACCGAAGATCACATTTAAAACAAAGATCTATCACCCGAACATTGACGAAAA
GGGGCAGGTCTGTCTGCCAGTAATTAGCGCTGAAAACTGGAAGCCAGCAACCAAAACCGACCAA
GTAATCCAGTCCCTCATAGCACTGGTGAATGACCCCCAGCCCGAGCACCCGCTTCGGGCTGACC
TAGCTGAAGAATACTCTAAGGACCGTAAAAAATTCTGTAAGAATGCTGAAGAGTTTACAAAGAA
ATATGGGGAAAAGCGACCTGTGGACTAAAATCTGCCACGATTGGTTCCAGCAAGTGTGAGCAGA
GGCCCCGTGCAGTGCATTCAGACACCCCGCAAAGCAGGACTCTGTGGAAATTGACACGTGCCAC
CGCCTGGCGTTCGCTTGTGGCAGTTACTAACTTTCTACAGTTTTCTTAATCAAAAGTGGTCTAG
GTAACCTGTAAAGAAAGGATTAAAAATTTAAGATGTTCTAGTTCTGCTCTCTTTGTTTTAAAAA
TCACTGCTTCAATCTATTCCAAAAGAATGGTGTTTCTTTTCTTGTCCAATTTTATCCAAAATCT
TCAAGTTGCATTTAGCCCATAATGTTTAAAAAAAAGGAAAAAAAAGGTTGTGGTTCCCTTTCTT
CCCTACCCTTGCCACTCCCACTTTCTGGCACCGAGTTTATTTTTCACTTACTTCCCCAGACCCG
GGGCCCGCCTCCACAAAAGAGAAGAGACTGCCCTGGCGGTCCTGGTGGCTTTTCTTAGCACGTG
TGGGACTGTTGCCCAGTGTGGGAGTTGGTTTAAATTCTCCTGACTCCAGTTTATAACATCCTTT
TAAAAAATTTAAAAACAAACAGCTACACCCCTCCTCCAGTCCTTCTCCTCAGTTCTTGTGTGAA
TCTCCAGCTGATGTTACCACAGTAACATCAGTTAATTGGGCAAGCCCTGATGTCAGTGTGTGTA
ACTGACCTCTGGCCTGGCCTGCACAGACAAACCCTATAATCACAGGTCTGTAGTGGCCCCGAAA
TGGGGGGCCTGCTAGTCAGGAGGATGCTGTGCACACTGTGTGTGATGAATCTCGCCGAAAGGCT
CCTGATGTCCCAGGTTGGCACTTCTTCCTGCAGCCATTGTAGAAGATCTGCTGGTCCTTGCAGG
CAAAGCTACAGCCAGAATGTCCGTTTGAAATTCCCAGCTCATCTGTCACCGAGTTTCATCTGAA
TGTGCCACGGAGCTTGCTCTCCACTTCCTCTGTGCAGCGGCCCCGCCACAGCCCTCCCTCGGCA
CACTTTGACCCTTTGTAGGATTGGAATTAGCAGGACTTGGCTATTTAAAGCACCAGTCTGGGGT
CTCCTGGGCCCCTGCTGACCCCTTCCTCCAGAGCAGCTGGCCCAGCCCGGGAACAAGACGGACT
TCCTCTCCCTTTGGACTCACAGCCTTTGCAGAGTCAAGCTCCACTTGAAGCTCACTCAGTAATA
TCCTTTCAATGTGTTTTATATTGTTTTGACTGCCTTTTTTTGTAGAAATAAAAATTGACCTTAG
AATTTATCATCAGATAAACTTGTAAAGATTTGAATATTAATGTCTTTTCAAGGCAAATGGGATT
GTCCCCAAACTAGTAGAGAATCTGTGTCGCTCTGACACCCCAAGGAAGCCGACGATCCAAATGC
CGTGTGTCACCAACCCTGCTTCTTCCACTGGCGGCTTCCCTTCTTGGCTTTTGGGGGGACTAGA
TCCTGTGGAGAAGATGACTTAAACTTTGCTTTTTGTTTTAATTTTAATTCTAGATCTTTCCGGT
CTGATCTGTGCAGAAGTGGGGAGTGATGGGCAGGTTAGGCAGCCTAACATCATTCAGGCGTGTG
GCCCCTGTGGTGTGTACATGAACTCAGCTTCTTTTGTCCTAGGTACGCCAAGGGCAGGTTTCTG
GAGACTCGTGTGCCCAGGATGGCAAGGGCACCGGGCTGGCGTTTCCGTATATGTCTCTTCATTA
GCAGAAAAATGATGATGGATTTTATTTCACTCACACTCCAATTTGTAATAAAATGCCAAATTCT
GTCAGAAACTATCTAAATAAGCCACCATTTGTTCTTGTTGCTTCTCTGGATCCAGAAATGTTGC
CATTCTTGGAAACTGTCCCATTGCTTCATATTTCTGCCAACGTAGCTCTGCCTGCCTGTCACCC
CCTCACTGCGCTCTGCTCACCACGGGAGGATACCTGTGTGCCAGCAGCCCCTCAGGGACTCTCA
GCCCTGGCACTGGCACCCCAGGGTTGGCCCCGTCAGCAGAGGCCTGGCTTTCGAGCCAGTGGGT
GTCTCTCCTTCAGGCCTGGGCGACTTGCTCCTGCCAGCCATGCCCTCAGGGTAGGCTCTGAGCA
AGCTGGTGAACAGCCTTGGCTGCTCCAAAACCAAAAAGCTGGGTCCTCTGGAGGAGGGGCGAGC
TGTGGAGCAGCCACCCACTGCTGCCCCTAGCTCACTCAGGAATTCACACCCGCCTGGTTTCTTC
AAGTGTGCCGGGTCCTTCCCTCTGCTCCCCACTCCCCACCACGGCAGAGAATAGGCTTTCTAAG
ATGCTGCGATCCCGTTCTGCTGCCCTTAATAAAAATGCTCTCAGACACTG

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Protein Sequences


Protein RefSeqs	XP_007973110	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_007973110 ⟸ XM_007974919

Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	UBE2L3	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations