Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Mir125b-2 (microRNA 125b-2) Mus musculus
Analyze
Symbol: Mir125b-2
Name: microRNA 125b-2
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: mir-125b-2; Mirn125b-2
Orthologs:
Homo sapiens (human) : MIR125B2 (microRNA 125b-2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mir125b2 (microRNA 125b-2)  Alliance
Canis lupus familiaris (dog) : MIR125B-2 (microRNA mir-125b-2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381677,646,273 - 77,646,343 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371677,646,518 - 77,646,588 (+)NCBIGRCm37mm9NCBIm37
Celera1677,873,203 - 77,873,273 (+)NCBICelera
Cytogenetic Map16 C3.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Promoters

Additional Information

External Database Links
 
More on Mir125b-2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1607571
Created: 2007-04-29
Species: Mus musculus
Last Modified: 2019-04-16
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.