IL27 (interleukin 27) - Rat Genome Database

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Gene: IL27 (interleukin 27) Sus scrofa
Analyze
Symbol: IL27
Name: interleukin 27
RGD ID: 14102791
Description: ENCODES a protein that exhibits cytokine activity (inferred); interleukin-27 receptor binding (inferred); signaling receptor binding (inferred); INVOLVED IN positive regulation of defense response to virus by host (ortholog); regulation of T cell proliferation (ortholog); response to bacterium (ortholog); PARTICIPATES IN interleukin-27 signaling pathway; ASSOCIATED WITH Acute-On-Chronic Liver Failure (ortholog); Arenaviridae infectious disease (ortholog); asthma (ortholog); FOUND IN cell surface (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: IL-27 subunit alpha; IL-27-A; IL-27p28; IL27-A; IL27A; interleukin 27 p28 subunit; Interleukin-27 p28 subunit; interleukin-27 subunit alpha; p28
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl318,421,981 - 18,427,915 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1318,421,962 - 18,427,916 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:19269039  


Genomics

Comparative Map Data
IL27
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl318,421,981 - 18,427,915 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1318,421,962 - 18,427,916 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
IL27
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381628,499,362 - 28,506,834 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1628,499,362 - 28,512,051 (-)EnsemblGRCh38hg38GRCh38
GRCh371628,510,683 - 28,518,155 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361628,418,184 - 28,425,656 (-)NCBINCBI36hg18NCBI36
Build 341628,418,472 - 28,425,633NCBI
Celera1627,685,614 - 27,693,084 (+)NCBI
Cytogenetic Map16p12.1-p11.2NCBI
HuRef1626,536,601 - 26,544,073 (-)NCBIHuRef
CHM1_11629,522,293 - 29,529,765 (-)NCBICHM1_1
T2T-CHM13v2.01628,888,944 - 28,896,415 (+)NCBI
Il27
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397126,188,181 - 126,194,197 (-)NCBIGRCm39mm39
GRCm39 Ensembl7126,188,182 - 126,194,113 (-)Ensembl
GRCm387126,589,009 - 126,595,035 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7126,589,010 - 126,594,941 (-)EnsemblGRCm38mm10GRCm38
MGSCv377133,732,809 - 133,738,424 (-)NCBIGRCm37mm9NCBIm37
MGSCv367126,380,443 - 126,386,058 (-)NCBImm8
Celera7126,438,423 - 126,444,039 (-)NCBICelera
Cytogenetic Map7F3NCBI
Il27
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21181,173,108 - 181,178,720 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1181,173,372 - 181,178,582 (-)Ensembl
Rnor_6.01198,003,615 - 198,010,112 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1198,003,683 - 198,008,893 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01204,981,789 - 204,987,782 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,730,394 - 185,735,604 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1178,831,320 - 178,837,817 (-)NCBICelera
Cytogenetic Map1q36NCBI
Il27
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554936,712,005 - 6,717,417 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554936,712,005 - 6,717,417 (-)NCBIChiLan1.0ChiLan1.0
IL27
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11628,979,717 - 28,984,655 (-)NCBIpanpan1.1PanPan1.1panPan2
IL27
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1618,243,988 - 18,248,369 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl618,244,040 - 18,247,635 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha619,822,685 - 19,827,046 (+)NCBI
ROS_Cfam_1.0618,380,027 - 18,384,391 (+)NCBI
ROS_Cfam_1.0 Ensembl618,380,086 - 18,384,093 (+)Ensembl
UMICH_Zoey_3.1618,179,035 - 18,183,396 (+)NCBI
UNSW_CanFamBas_1.0618,094,139 - 18,098,496 (+)NCBI
UU_Cfam_GSD_1.0618,410,212 - 18,414,571 (+)NCBI
Il27
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344123,875,494 - 123,879,941 (-)NCBI
SpeTri2.0NW_00493650111,972,715 - 11,978,152 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL27
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1526,348,559 - 26,358,028 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl526,348,848 - 26,356,360 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660683,217,584 - 3,222,518 (+)NCBIVero_WHO_p1.0
Il27
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478213,009,564 - 13,015,440 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462478213,009,450 - 13,015,548 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system hemolymphoid system reproductive system respiratory system
High
Medium
Low 1 1 2
Below cutoff 4 2 4 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000039070   ⟹   ENSSSCP00000051345
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl318,421,981 - 18,427,915 (+)Ensembl
RefSeq Acc Id: NM_001007520   ⟹   NP_001007521
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1318,422,095 - 18,427,630 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021085893   ⟹   XP_020941552
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1318,421,962 - 18,427,916 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001007521 (Get FASTA)   NCBI Sequence Viewer  
  XP_020941552 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAV54185 (Get FASTA)   NCBI Sequence Viewer  
  BAN09009 (Get FASTA)   NCBI Sequence Viewer  
  Q5S1V9 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020941552   ⟸   XM_021085893
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001007521   ⟸   NM_001007520
- Peptide Label: precursor
- UniProtKB: Q5S1V9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSSSCP00000051345   ⟸   ENSSSCT00000039070


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000039300 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000051345 ENTREZGENE
  ENSSSCP00000051345.1 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000039070 ENTREZGENE
  ENSSSCT00000039070.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro 4_helix_cytokine-like_core UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-27_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:493187 UniProtKB/Swiss-Prot
NCBI Gene IL27 ENTREZGENE
PANTHER PTHR20879 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A287B4I8_PIG UniProtKB/TrEMBL
  IL27A_PIG UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID VGNC:89101 ENTREZGENE