IFNB1 (interferon beta 1) - Rat Genome Database

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Gene: IFNB1 (interferon beta 1) Sus scrofa
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Symbol: IFNB1
Name: interferon beta 1
RGD ID: 14134245
Description: ENCODES a protein that exhibits chloramphenicol O-acetyltransferase activity (inferred); cytokine activity (inferred); cytokine receptor binding (inferred); INVOLVED IN adaptive immune response (ortholog); cellular response to dexamethasone stimulus (ortholog); cellular response to dsRNA (ortholog); ASSOCIATED WITH amelanotic melanoma (ortholog); anus benign neoplasm (ortholog); brain disease (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred); INTERACTS WITH cadmium nitrate; chloroquine; deoxynivalenol
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: IFN-beta; IFNb; interferon beta; interferon-beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1201,850,935 - 201,851,495 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11201,850,935 - 201,851,495 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21225,469,554 - 225,470,114 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap1q23-q27NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:1640116   PMID:11356957   PMID:11683720   PMID:16933611   PMID:20406849   PMID:22592217   PMID:23834966   PMID:23871214   PMID:25008936   PMID:25086295   PMID:25451299   PMID:26773386  
PMID:27314873   PMID:27718457   PMID:27896670   PMID:27984784   PMID:29793076   PMID:29864504   PMID:30473349   PMID:30473353   PMID:32452419   PMID:34452346  


Genomics

Comparative Map Data
IFNB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1201,850,935 - 201,851,495 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11201,850,935 - 201,851,495 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21225,469,554 - 225,470,114 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap1q23-q27NCBI
IFNB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38921,077,104 - 21,077,942 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl921,077,104 - 21,077,942 (-)EnsemblGRCh38hg38GRCh38
GRCh37921,077,103 - 21,077,941 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36921,067,104 - 21,067,943 (-)NCBINCBI36hg18NCBI36
Build 34921,067,103 - 21,067,943NCBI
Celera921,015,373 - 21,016,212 (-)NCBI
Cytogenetic Map9p21.3NCBI
HuRef921,040,313 - 21,041,152 (-)NCBIHuRef
CHM1_1921,076,893 - 21,077,732 (-)NCBICHM1_1
T2T-CHM13v2.0921,090,986 - 21,091,824 (-)NCBI
Ifnb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39488,440,262 - 88,441,031 (-)NCBIGRCm39mm39
GRCm39 Ensembl488,440,262 - 88,441,011 (-)Ensembl
GRCm38488,522,025 - 88,522,794 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl488,522,025 - 88,522,774 (-)EnsemblGRCm38mm10GRCm38
MGSCv37488,167,929 - 88,168,698 (-)NCBIGRCm37mm9NCBIm37
MGSCv36487,993,256 - 87,994,025 (-)NCBImm8
Celera487,037,706 - 87,038,475 (-)NCBICelera
Cytogenetic Map4C4NCBI
cM Map441.91NCBI
Ifnb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25103,020,969 - 103,021,523 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl5103,020,969 - 103,021,523 (-)Ensembl
Rnor_6.05106,865,192 - 106,865,746 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5106,865,192 - 106,865,746 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05110,843,902 - 110,844,456 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45107,837,628 - 107,838,182 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15107,842,853 - 107,843,408 (-)NCBI
Celera5100,095,218 - 100,095,772 (+)NCBICelera
RH 3.4 Map5746.3RGD
Cytogenetic Map5q32NCBI
Ifnb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495543423,301,623 - 23,302,304 (-)NCBIChiLan1.0ChiLan1.0
IFNB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1921,540,849 - 21,541,695 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0920,884,742 - 20,886,317 (-)NCBIMhudiblu_PPA_v0panPan3
IFNB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11140,668,295 - 40,668,855 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1140,668,295 - 40,668,855 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1139,330,806 - 39,331,366 (-)NCBI
ROS_Cfam_1.01141,610,249 - 41,610,809 (-)NCBI
ROS_Cfam_1.0 Ensembl1141,610,249 - 41,610,809 (-)Ensembl
UMICH_Zoey_3.11140,302,366 - 40,302,926 (-)NCBI
UNSW_CanFamBas_1.01140,090,657 - 40,091,217 (-)NCBI
UU_Cfam_GSD_1.01140,726,193 - 40,726,753 (-)NCBI
Ifnb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947155,066,763 - 155,067,326 (-)NCBI
SpeTri2.0NW_0049366522,736,270 - 2,736,833 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
Ifnb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473625,099,061 - 25,099,746 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system
High
Medium
Low
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000005691   ⟹   ENSSSCP00000005550
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1201,850,935 - 201,851,495 (+)Ensembl
RefSeq Acc Id: NM_001003923   ⟹   NP_001003923
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11201,850,935 - 201,851,495 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001003923   ⟸   NM_001003923
- Peptide Label: precursor
- UniProtKB: Q68IQ4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000005550   ⟸   ENSSSCT00000005691


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000005163 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00005021718 UniProtKB/TrEMBL
  ENSSSCG00015029022 UniProtKB/TrEMBL
  ENSSSCG00025055931 UniProtKB/TrEMBL
  ENSSSCG00030053628 UniProtKB/TrEMBL
  ENSSSCG00035019170 UniProtKB/TrEMBL
  ENSSSCG00040069322 UniProtKB/TrEMBL
  ENSSSCG00045011611 UniProtKB/TrEMBL
  ENSSSCG00050064948 UniProtKB/TrEMBL
  ENSSSCG00055006914 UniProtKB/TrEMBL
  ENSSSCG00060012989 UniProtKB/TrEMBL
  ENSSSCG00065055305 UniProtKB/TrEMBL
  ENSSSCG00070030326 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000005550.1 UniProtKB/TrEMBL
  ENSSSCP00005020890.1 UniProtKB/TrEMBL
  ENSSSCP00015015313.1 UniProtKB/TrEMBL
  ENSSSCP00025033201.1 UniProtKB/TrEMBL
  ENSSSCP00030034213.1 UniProtKB/TrEMBL
  ENSSSCP00035009324.1 UniProtKB/TrEMBL
  ENSSSCP00040042045.1 UniProtKB/TrEMBL
  ENSSSCP00045013473.1 UniProtKB/TrEMBL
  ENSSSCP00050037903.1 UniProtKB/TrEMBL
  ENSSSCP00055010522.1 UniProtKB/TrEMBL
  ENSSSCP00060006770.1 UniProtKB/TrEMBL
  ENSSSCP00065032915.1 UniProtKB/TrEMBL
  ENSSSCP00070052039.1 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000005691.2 UniProtKB/TrEMBL
  ENSSSCT00005034280.1 UniProtKB/TrEMBL
  ENSSSCT00015038565.1 UniProtKB/TrEMBL
  ENSSSCT00025076595.1 UniProtKB/TrEMBL
  ENSSSCT00030074792.1 UniProtKB/TrEMBL
  ENSSSCT00035024789.1 UniProtKB/TrEMBL
  ENSSSCT00040094984.1 UniProtKB/TrEMBL
  ENSSSCT00045019653.1 UniProtKB/TrEMBL
  ENSSSCT00050088424.1 UniProtKB/TrEMBL
  ENSSSCT00055013382.1 UniProtKB/TrEMBL
  ENSSSCT00060017055.1 UniProtKB/TrEMBL
  ENSSSCT00065075687.1 UniProtKB/TrEMBL
  ENSSSCT00070061048.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.10 UniProtKB/TrEMBL
InterPro 4_helix_cytokine-like_core UniProtKB/TrEMBL
  Interferon_alpha/beta/delta UniProtKB/TrEMBL
  Interferon_beta UniProtKB/TrEMBL
KEGG Report ssc:445459 UniProtKB/TrEMBL
NCBI Gene IFNB1 ENTREZGENE
PANTHER PTHR11691 UniProtKB/TrEMBL
  PTHR11691:SF68 UniProtKB/TrEMBL
Pfam Interferon UniProtKB/TrEMBL
PRINTS INTERFERONAB UniProtKB/TrEMBL
PROSITE INTERFERON_A_B_D UniProtKB/TrEMBL
SMART IFabd UniProtKB/TrEMBL
Superfamily-SCOP SSF47266 UniProtKB/TrEMBL
UniProt A0A4X1WC07_PIG UniProtKB/TrEMBL
  A0A8D0J9V5_PIG UniProtKB/TrEMBL
  A1E3C5_PIG UniProtKB/TrEMBL
  Q29412_PIG UniProtKB/TrEMBL
  Q68IQ4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:89038 ENTREZGENE