IL10 (interleukin 10) - Rat Genome Database

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Gene: IL10 (interleukin 10) Canis lupus familiaris
Analyze
Symbol: IL10
Name: interleukin 10
RGD ID: 12383470
Description: ENCODES a protein that exhibits interleukin-10 receptor binding (ortholog); INVOLVED IN aging (ortholog); branching involved in labyrinthine layer morphogenesis (ortholog); cellular response to antibiotic (ortholog); PARTICIPATES IN Interleukin-10 signaling pathway; interleukin-4 signaling pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); Actinic Cheilitis (ortholog); Acute Experimental Pancreatitis (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CSIF; cytokine synthesis inhibitory factor; IL-10; interleukin-10
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.175,933,285 - 5,937,057 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl75,933,285 - 5,937,057 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha75,497,391 - 5,501,163 (-)NCBI
ROS_Cfam_1.075,622,589 - 5,626,365 (-)NCBI
ROS_Cfam_1.0 Ensembl75,622,079 - 5,626,428 (-)Ensembl
UMICH_Zoey_3.175,557,139 - 5,560,910 (-)NCBI
UNSW_CanFamBas_1.075,658,009 - 5,661,775 (-)NCBI
UU_Cfam_GSD_1.075,697,728 - 5,701,500 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
abdominal aortic aneurysm  (ISO)
Actinic Cheilitis  (ISO)
Acute Experimental Pancreatitis  (ISO)
acute kidney failure  (ISO)
Acute Liver Failure  (ISO)
Acute Lung Injury  (ISO)
acute lymphoblastic leukemia  (ISO)
acute myeloid leukemia  (ISO)
acute pancreatitis  (ISO)
adult respiratory distress syndrome  (ISO)
adult T-cell leukemia/lymphoma  (ISO)
aggressive periodontitis  (ISO)
Airway Obstruction  (ISO)
allergic conjunctivitis  (ISO)
allergic contact dermatitis  (ISO)
allergic rhinitis  (ISO)
Alveolar Bone Loss  (ISO)
Alzheimer's disease  (ISO)
anemia  (ISO)
Animal Disease Models  (ISO)
anogenital venereal wart  (ISO)
anti-basement membrane glomerulonephritis  (ISO)
aphthous stomatitis  (ISO)
appendicitis  (ISO)
arteriosclerosis  (ISO)
Asthenopia  (ISO)
asthma  (ISO)
atopic dermatitis  (ISO)
autistic disorder  (ISO)
autoimmune hemolytic anemia  (ISO)
autoimmune hepatitis  (ISO)
autoimmune thrombocytopenic purpura  (ISO)
B-Cell Chronic Lymphocytic Leukemia  (ISO)
bacterial infectious disease  (ISO)
bacterial pneumonia  (ISO)
Behcet's disease  (ISO)
Brain Injuries  (ISO)
Breast Neoplasms  (ISO)
Bronchial Hyperreactivity  (ISO)
bronchus carcinoma  (ISO)
Burns  (ISO)
carotid artery disease  (ISO)
carotid stenosis  (ISO)
celiac disease  (ISO)
central nervous system lymphoma  (ISO)
cervical cancer  (ISO)
Chagas Cardiomyopathy  (ISO)
choroid disease  (ISO)
Choroidal Neovascularization  (ISO)
Chronic Bronchitis  (ISO)
Chronic Hepatitis C  (ISO)
chronic myeloid leukemia  (ISO)
Chronic Periodontitis  (ISO)
colitis  (ISO)
colon cancer  (ISO)
common cold  (ISO)
Common Variable Immunodeficiency 7  (ISO)
congestive heart failure  (ISO)
coronary artery disease  (ISO)
Coronavirus infectious disease  (ISO)
COVID-19  (ISO)
Crohn's disease  (ISO)
cutaneous leishmaniasis  (ISO)
cytomegalovirus retinitis  (ISO)
decubitus ulcer  (ISO)
diabetes mellitus  (ISO)
Diabetic Cardiomyopathies  (ISO)
Diabetic Nephropathies  (ISO)
diabetic retinopathy  (ISO)
diffuse scleroderma  (ISO)
dilated cardiomyopathy  (ISO)
disseminated intravascular coagulation  (ISO)
drug allergy  (ISO)
Drug-Related Side Effects and Adverse Reactions  (ISO)
dry eye syndrome  (ISO)
Dysbiosis  (ISO)
Dyspepsia  (ISO)
Eales Disease  (ISO)
endometrial cancer  (ISO)
endometriosis  (ISO)
Endotoxemia  (ISO)
Entamoebiasis  (ISO)
Enterocolitis  (ISO)
Enterovirus Infections  (ISO)
esophageal cancer  (ISO)
Experimental Arthritis  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Autoimmune Myocarditis  (ISO)
Experimental Autoimmune Uveitis  (ISO)
Experimental Autoimmune Uveoretinitis  (ISO)
Experimental Colitis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
Eye Burns  (ISO)
factor VIII deficiency  (ISO)
Fanconi anemia  (ISO)
fatty liver disease  (ISO)
Femoral Fractures  (ISO)
gallbladder carcinoma  (ISO)
gastric dilatation  (ISO)
Gastro-Enteropancreatic Neuroendocrine Tumor  (ISO)
gastrointestinal stromal tumor  (ISO)
Genetic Predisposition to Disease  (ISO)
gestational diabetes  (ISO)
glomerulonephritis  (ISO)
glucosephosphate dehydrogenase deficiency  (ISO)
Graft vs Host Disease  (ISO)
granulomatosis with polyangiitis  (ISO)
Graves ophthalmopathy  (ISO)
Graves' disease  (ISO)
Hearing Loss  (ISO)
Heat Stroke  (ISO)
Hemorrhagic Shock  (ISO)
Heparin-induced Thrombocytopenia  (ISO)
hepatitis B  (ISO)
hepatitis C  (ISO)
hepatocellular carcinoma  (ISO)
herpes simplex virus keratitis  (ISO)
herpes zoster  (ISO)
high grade glioma  (ISO)
Hodgkin's lymphoma  (ISO)
human immunodeficiency virus infectious disease  (ISO)
Human Influenza  (ISO)
Human Viral Hepatitis  (ISO)
Hyperalgesia  (ISO)
hypertension  (ISO)
hyperthyroidism  (ISO)
hypothyroidism  (ISO)
ileitis  (ISO)
Immediate Hypersensitivity  (ISO)
Inflammation  (ISO)
inflammatory bowel disease  (ISO)
intermediate uveitis  (ISO)
intestinal obstruction  (ISO)
irritable bowel syndrome  (ISO)
Kidney Reperfusion Injury  (ISO)
leishmaniasis  (ISO)
lip cancer  (ISO)
liver benign neoplasm  (ISO)
liver cancer  (ISO)
liver carcinoma  (ISO)
liver cirrhosis  (ISO)
Liver Reperfusion Injury  (ISO)
lung disease  (ISO)
Lung Neoplasms  (ISO)
lung non-small cell carcinoma  (ISO)
major depressive disorder  (ISO)
Malignant Pleural Effusions  (ISO)
Mammary Neoplasms, Experimental  (ISO)
Middle East respiratory syndrome  (ISO)
mitral valve stenosis  (ISO)
mucositis  (ISO)
multiple myeloma  (ISO)
Multiple Organ Failure  (ISO)
multiple sclerosis  (ISO)
Murine Acquired Immunodeficiency Syndrome  (ISO)
myocardial infarction  (ISO)
Myocardial Reperfusion Injury  (ISO)
myocarditis  (ISO)
Nasal Polyps  (ISO)
Neoplasm Metastasis  (ISO)
Neuralgia  (ISO)
non-alcoholic fatty liver disease  (ISO)
non-alcoholic steatohepatitis  (ISO)
obesity  (ISO)
obstructive sleep apnea  (ISO)
occupational dermatitis  (ISO)
Ocular Toxoplasmosis  (ISO)
ocular tuberculosis  (ISO)
open-angle glaucoma  (ISO)
oral squamous cell carcinoma  (ISO)
otitis media  (ISO)
ovarian cancer  (ISO)
pancreatic cancer  (ISO)
pancreatitis  (ISO)
panuveitis  (ISO)
parathyroid carcinoma  (ISO)
pericardial effusion  (ISO)
perinatal necrotizing enterocolitis  (ISO)
periodontitis  (ISO)
plasmacytoma  (ISO)
pleurisy  (ISO)
pneumonia  (ISO)
postpartum depression  (ISO)
Pregnancy-associated Malaria  (ISO)
primary biliary cholangitis  (ISO)
Primary Graft Dysfunction  (ISO)
Prostatic Neoplasms  (ISO)
prostatitis  (ISO)
Pseudomonas Aeruginosa Keratitis  (ISO)
psoriasis  (ISO)
pulmonary eosinophilia  (ISO)
pulmonary hypertension  (ISO)
Radiation Injuries, Experimental  (ISO)
Reperfusion Injury  (ISO)
respiratory allergy  (ISO)
respiratory syncytial virus infectious disease  (ISO)
retinal artery occlusion  (ISO)
retinal disease  (ISO)
retinopathy of prematurity  (ISO)
Retroviridae Infections  (ISO)
rheumatic heart disease  (ISO)
rheumatoid arthritis  (ISO)
Rhinosinusitis  (ISO)
schizophrenia  (ISO)
sciatic neuropathy  (ISO)
Seasonal Allergic Rhinitis  (ISO)
Sepsis  (ISO)
severe acute respiratory syndrome  (ISO)
shigellosis  (ISO)
Shwartzman phenomenon  (ISO)
sickle cell anemia  (ISO)
Sjogren's syndrome  (ISO)
skin disease  (ISO)
Spinal Cord Injuries  (ISO)
Splenomegaly  (ISO)
Staphylococcal Infections  (ISO)
Staphylococcal Pneumonia  (ISO)
stomach cancer  (ISO)
Stroke  (ISO)
systemic lupus erythematosus  (ISO)
thrombocytopenia  (ISO)
thrombosis  (ISO)
thyrotoxicosis  (ISO)
tongue squamous cell carcinoma  (ISO)
toxic encephalopathy  (ISO)
toxic shock syndrome  (ISO)
Toxoplasma Chorioretinitis  (ISO)
trachoma  (ISO)
transient cerebral ischemia  (ISO)
Transplant Rejection  (ISO)
trichinosis  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
ulcerative colitis  (ISO)
uveitis  (ISO)
vasculitis  (ISO)
Venous Thrombosis  (ISO)
Ventilator-Induced Lung Injury  (ISO)
viral pneumonia  (ISO)
visceral leishmaniasis  (ISO)
Waldenstroem's macroglobulinemia  (ISO)
Weight Loss  (ISO)
Wilson disease  (ISO)
Wounds and Injuries  (ISO)
Wounds, Penetrating  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aging  (ISO)
antigen processing and presentation of exogenous peptide antigen via MHC class II  (NAS)
branching involved in labyrinthine layer morphogenesis  (IEA,ISO)
cellular response to antibiotic  (ISO)
cellular response to estradiol stimulus  (ISO)
cellular response to hepatocyte growth factor stimulus  (IEA,ISO)
cellular response to lipopolysaccharide  (IEA,ISO)
cellular response to virus  (ISO)
chronic inflammatory response to antigenic stimulus  (IEA,ISO)
defense response to bacterium  (IEA,ISO)
defense response to protozoan  (IEA,ISO)
immune response  (IEA,ISO)
liver regeneration  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of autophagy  (IEA)
negative regulation of B cell proliferation  (IEA,ISO,ISS)
negative regulation of cell population proliferation  (IEA)
negative regulation of chronic inflammatory response to antigenic stimulus  (IEA,ISO)
negative regulation of cytokine activity  (IEA)
negative regulation of cytokine production  (IEA,ISO)
negative regulation of cytokine production involved in immune response  (IEA,ISS)
negative regulation of endothelial cell apoptotic process  (IEA,ISO)
negative regulation of heterotypic cell-cell adhesion  (IEA)
negative regulation of hydrogen peroxide-induced neuron death  (IEA)
negative regulation of inflammatory response  (IEA,ISO,ISS)
negative regulation of interleukin-12 production  (IEA,ISO)
negative regulation of interleukin-6 production  (IEA,ISS)
negative regulation of membrane protein ectodomain proteolysis  (IEA,ISS)
negative regulation of MHC class II biosynthetic process  (IEA)
negative regulation of myeloid dendritic cell activation  (IEA,ISO)
negative regulation of neuron apoptotic process  (ISO)
negative regulation of nitric oxide biosynthetic process  (ISO)
negative regulation of sensory perception of pain  (ISO)
negative regulation of tumor necrosis factor production  (IEA,ISO)
negative regulation of type II interferon production  (IEA,ISO)
negative regulation of vascular associated smooth muscle cell proliferation  (IEA)
positive regulation of B cell apoptotic process  (IEA,ISO,ISS)
positive regulation of cell cycle  (IEA)
positive regulation of cytokine production  (IEA,ISS)
positive regulation of DNA-binding transcription factor activity  (IEA,ISS)
positive regulation of DNA-templated transcription  (IEA,ISS)
positive regulation of endothelial cell proliferation  (IEA)
positive regulation of immunoglobulin production  (IEA,ISO)
positive regulation of macrophage activation  (ISO)
positive regulation of MHC class II biosynthetic process  (IEA,ISO)
positive regulation of miRNA transcription  (IEA)
positive regulation of plasma cell differentiation  (IEA,ISO)
positive regulation of receptor signaling pathway via JAK-STAT  (IEA)
positive regulation of signaling receptor activity  (IEA,ISO)
positive regulation of sprouting angiogenesis  (IEA)
positive regulation of transcription by RNA polymerase II  (IEA)
regulation of complement-dependent cytotoxicity  (ISO)
regulation of cytokine production  (IEA)
regulation of gene expression  (IEA,ISO)
regulation of response to wounding  (IEA)
regulation of sensory perception of pain  (ISO)
regulation of synapse organization  (ISO)
response to activity  (ISO)
response to carbon monoxide  (ISO)
response to glucocorticoid  (IEA,ISO,ISS)
response to inactivity  (ISO)
response to insulin  (ISO)
response to lipopolysaccharide  (ISO)
response to molecule of bacterial origin  (IEA,ISS)
response to organic substance  (ISO)
response to xenobiotic stimulus  (ISO)
signal transduction  (IEA)

Cellular Component
extracellular region  (IEA,NAS)
extracellular space  (IEA,ISO,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:8746793   PMID:11730929   PMID:23351639   PMID:23911411   PMID:24487092  


Genomics

Comparative Map Data
IL10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.175,933,285 - 5,937,057 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl75,933,285 - 5,937,057 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha75,497,391 - 5,501,163 (-)NCBI
ROS_Cfam_1.075,622,589 - 5,626,365 (-)NCBI
ROS_Cfam_1.0 Ensembl75,622,079 - 5,626,428 (-)Ensembl
UMICH_Zoey_3.175,557,139 - 5,560,910 (-)NCBI
UNSW_CanFamBas_1.075,658,009 - 5,661,775 (-)NCBI
UU_Cfam_GSD_1.075,697,728 - 5,701,500 (-)NCBI
IL10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381206,767,602 - 206,772,494 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1206,767,602 - 206,774,541 (-)EnsemblGRCh38hg38GRCh38
GRCh371206,940,947 - 206,945,839 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361205,007,571 - 205,012,462 (-)NCBINCBI36hg18NCBI36
Build 341203,329,342 - 203,334,234NCBI
Celera1180,192,396 - 180,197,294 (-)NCBI
Cytogenetic Map1q32.1NCBI
HuRef1177,639,274 - 177,644,165 (-)NCBIHuRef
CHM1_11208,213,574 - 208,218,465 (-)NCBICHM1_1
T2T-CHM13v2.01206,031,803 - 206,036,695 (-)NCBI
Il10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391130,947,459 - 130,952,707 (+)NCBIGRCm39mm39
GRCm39 Ensembl1130,947,582 - 130,952,711 (+)Ensembl
GRCm381131,019,845 - 131,024,970 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1131,019,845 - 131,024,974 (+)EnsemblGRCm38mm10GRCm38
MGSCv371132,916,422 - 132,921,547 (+)NCBIGRCm37mm9NCBIm37
MGSCv361132,847,393 - 132,852,516 (+)NCBImm8
Celera1133,642,456 - 133,647,581 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map156.89NCBI
Il10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21342,472,625 - 42,477,308 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1342,472,839 - 42,477,313 (+)Ensembl
Rnor_6.01347,738,933 - 47,743,392 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1347,739,526 - 47,743,392 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01352,824,594 - 52,828,560 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41343,953,900 - 43,957,766 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11343,967,906 - 43,972,374 (+)NCBI
Celera1342,821,569 - 42,825,416 (+)NCBICelera
Cytogenetic Map13q13NCBI
Il10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540642,307,664 - 42,312,779 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540642,307,789 - 42,312,255 (-)NCBIChiLan1.0ChiLan1.0
IL10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11186,648,289 - 186,653,155 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1186,648,289 - 186,653,371 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01182,369,234 - 182,374,207 (-)NCBIMhudiblu_PPA_v0panPan3
Il10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934468,594,566 - 68,598,867 (+)NCBI
SpeTri2.0NW_0049365575,834,874 - 5,838,502 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl967,400,728 - 67,405,378 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1967,400,727 - 67,405,941 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2973,757,707 - 73,762,925 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IL10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12522,590,389 - 22,595,877 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2522,590,962 - 22,594,836 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605523,288,754 - 23,293,715 (+)NCBIVero_WHO_p1.0
Il10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248074,687,176 - 4,691,732 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248074,687,249 - 4,691,658 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 6 5 2
Low 5 1 22 6 6 6 12 5 4
Below cutoff 4 6 7

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000018154   ⟹   ENSCAFP00000016812
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl75,933,285 - 5,937,057 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845002231   ⟹   ENSCAFP00845001764
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl75,622,079 - 5,626,428 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845002236   ⟹   ENSCAFP00845001769
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl75,622,082 - 5,626,424 (-)Ensembl
RefSeq Acc Id: NM_001003077   ⟹   NP_001003077
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.175,933,285 - 5,937,057 (-)NCBI
Dog10K_Boxer_Tasha75,497,391 - 5,501,163 (-)NCBI
ROS_Cfam_1.075,622,589 - 5,626,365 (-)NCBI
UMICH_Zoey_3.175,557,139 - 5,560,910 (-)NCBI
UNSW_CanFamBas_1.075,658,009 - 5,661,775 (-)NCBI
UU_Cfam_GSD_1.075,697,728 - 5,701,500 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001003077   ⟸   NM_001003077
- Peptide Label: precursor
- UniProtKB: P48411 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSCAFP00000016812   ⟸   ENSCAFT00000018154
RefSeq Acc Id: ENSCAFP00845001769   ⟸   ENSCAFT00845002236
RefSeq Acc Id: ENSCAFP00845001764   ⟸   ENSCAFT00845002231

Damaging Variants


Assembly: CanFam3.1
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
7 5937011 5937012 C T snv Chihuahua (CH019), Dachshund (DH098), Rhodesian Ridgeback (RR224), Rhodesian Ridgeback (RR098), Old English Sheepdog (OS001)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000011443 Ensembl
  ENSCAFG00030021895 UniProtKB/TrEMBL
  ENSCAFG00040013882 UniProtKB/TrEMBL
  ENSCAFG00845001289 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00030035111.1 UniProtKB/TrEMBL
  ENSCAFP00040022314 UniProtKB/TrEMBL
  ENSCAFP00845001764.1 UniProtKB/TrEMBL
  ENSCAFP00845001769 ENTREZGENE
  ENSCAFP00845001769.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00030040236.1 UniProtKB/TrEMBL
  ENSCAFT00040025664 UniProtKB/TrEMBL
  ENSCAFT00845002231.1 UniProtKB/TrEMBL
  ENSCAFT00845002236 ENTREZGENE
  ENSCAFT00845002236.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro 4_helix_cytokine-like_core UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-10/19/20/22/24/26_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-10_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report cfa:403628 UniProtKB/Swiss-Prot
NCBI Gene IL10 ENTREZGENE
Pfam IL10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS INTRLEUKIN10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE INTERLEUKIN_10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IL10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47266 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8C0SL83_CANLF UniProtKB/TrEMBL
  A0A8I3MNZ8_CANLF UniProtKB/TrEMBL
  F1PZ65_CANLF UniProtKB/TrEMBL
  IL10_CANLF UniProtKB/Swiss-Prot, ENTREZGENE
  W8E075_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:41928 ENTREZGENE