Ido1 (indoleamine 2,3-dioxygenase 1) - Rat Genome Database

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Gene: Ido1 (indoleamine 2,3-dioxygenase 1) Heterocephalus glaber
Analyze
Symbol: Ido1
Name: indoleamine 2,3-dioxygenase 1
RGD ID: 18912360
Description: ENCODES a protein that exhibits amino acid binding (ortholog); indoleamine 2,3-dioxygenase activity (ortholog); oxygen binding (ortholog); INVOLVED IN inflammatory response (ortholog); kynurenic acid biosynthetic process (ortholog); L-tryptophan catabolic process to kynurenine (ortholog); PARTICIPATES IN kynurenine metabolic pathway; tryptophan metabolic pathway; ASSOCIATED WITH acquired immunodeficiency syndrome (ortholog); Acute Lung Injury (ortholog); Animal Toxoplasmosis (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); smooth muscle contractile fiber (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247803,685,069 - 3,697,474 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247803,684,941 - 3,697,506 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ido1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247803,685,069 - 3,697,474 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247803,684,941 - 3,697,506 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
IDO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38839,913,891 - 39,928,790 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl839,902,275 - 39,928,790 (+)EnsemblGRCh38hg38GRCh38
GRCh37839,771,410 - 39,786,309 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36839,890,485 - 39,905,107 (+)NCBINCBI36Build 36hg18NCBI36
Build 34839,890,484 - 39,905,102NCBI
Celera838,723,061 - 38,737,682 (+)NCBICelera
Cytogenetic Map8p11.21NCBI
HuRef838,304,038 - 38,319,017 (+)NCBIHuRef
CHM1_1839,817,930 - 39,832,909 (+)NCBICHM1_1
T2T-CHM13v2.0840,190,729 - 40,205,625 (+)NCBIT2T-CHM13v2.0
Ido1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39825,074,148 - 25,086,987 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl825,074,152 - 25,087,025 (-)EnsemblGRCm39 Ensembl
GRCm38824,584,133 - 24,596,952 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl824,584,136 - 24,597,009 (-)EnsemblGRCm38mm10GRCm38
MGSCv37825,694,613 - 25,707,481 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36826,049,686 - 26,062,554 (-)NCBIMGSCv36mm8
Celera826,068,313 - 26,081,132 (-)NCBICelera
Cytogenetic Map8A2NCBI
cM Map812.76NCBI
Ido1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81674,133,259 - 74,145,328 (+)NCBIGRCr8
mRatBN7.21667,430,654 - 67,442,726 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1667,430,578 - 67,442,730 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1672,707,823 - 72,719,592 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01676,112,135 - 76,124,005 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01671,361,330 - 71,373,199 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01672,216,326 - 72,228,098 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1672,216,326 - 72,228,098 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01671,866,330 - 71,878,339 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41671,866,340 - 71,878,373 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11671,866,604 - 71,878,638 (+)NCBI
Celera1665,330,156 - 65,341,814 (+)NCBICelera
Cytogenetic Map16q12.5NCBI
Ido1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555362,943,611 - 2,955,829 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555362,944,770 - 2,955,829 (-)NCBIChiLan1.0ChiLan1.0
IDO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2758,370,241 - 58,385,003 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1834,087,337 - 34,102,106 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0839,108,310 - 39,123,611 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1836,606,721 - 36,632,371 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl836,617,312 - 36,632,352 (+)Ensemblpanpan1.1panPan2
IDO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11625,391,759 - 25,407,161 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1625,391,754 - 25,407,048 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1625,901,596 - 25,916,857 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01627,218,925 - 27,234,204 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1627,218,820 - 27,234,153 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11625,516,922 - 25,532,182 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01626,072,694 - 26,087,946 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01626,131,508 - 26,146,796 (-)NCBIUU_Cfam_GSD_1.0
Ido1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494348,593,856 - 48,608,521 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936843657,979 - 672,700 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936843658,058 - 672,662 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IDO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl179,245,196 - 9,260,473 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1179,245,283 - 9,260,140 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21710,913,978 - 10,928,837 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IDO1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1837,930,910 - 37,950,790 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl837,930,562 - 37,946,505 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660523,981,103 - 3,996,711 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000004400   ⟹   ENSHGLP00000004340
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247803,685,069 - 3,697,474 (-)Ensembl
RefSeq Acc Id: XM_004855319   ⟹   XP_004855376
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247803,684,941 - 3,697,506 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004855376 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000004340
GenBank Protein JAO00082 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004855376   ⟸   XM_004855319
- UniProtKB: A0A0P6JCP1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000004340   ⟸   ENSHGLT00000004400


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000003174 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000004400 ENTREZGENE
Gene3D-CATH 1.20.58.480 UniProtKB/TrEMBL
InterPro Indolamine_dOase UniProtKB/TrEMBL
  Trp/Indoleamine_2_3_dOase-like UniProtKB/TrEMBL
KEGG Report hgl:101723745 UniProtKB/TrEMBL
NCBI Gene Ido1 ENTREZGENE
PANTHER INDOLEAMINE 2,3-DIOXYGENASE 1 UniProtKB/TrEMBL
  PTHR28657 UniProtKB/TrEMBL
Pfam IDO UniProtKB/TrEMBL
PROSITE IDO_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF140959 UniProtKB/TrEMBL
UniProt A0A0P6JCP1 ENTREZGENE, UniProtKB/TrEMBL