B9D2 (B9 domain containing 2) - Rat Genome Database

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Gene: B9D2 (B9 domain containing 2) Canis lupus familiaris
Analyze
Symbol: B9D2 (Ensembl: TGFB1)
Name: B9 domain containing 2 (Ensembl:transforming growth factor beta 1)
RGD ID: 12362351
Description: ENCODES a protein that exhibits cytokine activity (ortholog); deubiquitinase activator activity (ortholog); enzyme binding (ortholog); INVOLVED IN adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (ortholog); animal organ regeneration (ortholog); aortic valve morphogenesis (ortholog); PARTICIPATES IN altered transforming growth factor-beta Smad dependent signaling pathway; colorectal cancer pathway; glypican signaling pathway; ASSOCIATED WITH acromicric dysplasia (ortholog); actinic keratosis (ortholog); acute kidney failure (ortholog); FOUND IN axon (ortholog); cell surface (ortholog); collagen-containing extracellular matrix (ortholog); INTERACTS WITH ochratoxin A; testosterone
Type: protein-coding
RefSeq Status: MODEL
Previously known as: B9 domain-containing protein 2; B9 protein domain 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11112,621,832 - 112,627,726 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1112,621,633 - 112,643,885 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1112,025,951 - 112,032,055 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01113,219,930 - 113,226,035 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1113,219,701 - 113,241,694 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11112,781,179 - 112,787,278 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01112,413,522 - 112,419,614 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01113,406,803 - 113,412,909 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acromicric dysplasia  (ISO)
actinic keratosis  (ISO)
acute kidney failure  (ISO)
Acute Lung Injury  (ISO)
adenocarcinoma  (ISO)
alcohol use disorder  (ISO)
alcoholic liver cirrhosis  (ISO)
allergic conjunctivitis  (ISO)
allergic disease  (ISO)
allergic rhinitis  (ISO)
Anetoderma  (ISO)
anogenital venereal wart  (ISO)
aortic valve insufficiency  (ISO)
aphthous stomatitis  (ISO)
aplastic anemia  (ISO)
arteriosclerosis  (ISO)
asthma  (ISO)
atopic dermatitis  (ISO)
atrial fibrillation  (ISO)
autoimmune hepatitis  (ISO)
autoimmune thrombocytopenic purpura  (ISO)
bacterial pneumonia  (ISO)
Behcet's disease  (ISO)
berylliosis  (ISO)
biliary atresia  (ISO)
brain disease  (ISO)
brain ischemia  (ISO)
breast cancer  (ISO)
Cachexia  (ISO)
calcinosis  (ISO)
Camurati-Engelmann disease  (ISO)
carcinoma  (ISO)
carcinosarcoma  (ISO)
Cardiac Fibrosis  (ISO)
Cardiomegaly  (ISO)
carotid artery disease  (ISO)
Carotid Artery Injuries  (ISO)
Carpenter syndrome 2  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
chlamydia  (ISO)
cholangiocarcinoma  (ISO)
chorioamnionitis  (ISO)
Chronic Experimental Pancreatitis  (ISO)
Chronic Hepatitis  (ISO)
Chronic Hepatitis B  (ISO)
chronic myeloid leukemia  (ISO)
chronic obstructive pulmonary disease  (ISO)
cleft palate  (ISO)
colon adenocarcinoma  (ISO)
colon cancer  (ISO)
colon carcinoma  (ISO)
colorectal cancer  (ISO)
Colorectal Neoplasms  (ISO)
congenital hypoplastic anemia  (ISO)
Copper-Overload Cirrhosis  (ISO)
craniosynostosis 1  (ISO)
cystic fibrosis  (ISO)
degenerative disc disease  (ISO)
diabetes mellitus  (ISO)
Diabetic Nephropathies  (ISO)
diabetic neuropathy  (ISO)
Diamond-Blackfan anemia  (ISO)
Diaphragmatic Hernia  (ISO)
Dilatation, Pathologic  (ISO)
dry eye syndrome  (ISO)
Duchenne muscular dystrophy  (ISO)
duodenal ulcer  (ISO)
Ehlers-Danlos syndrome  (ISO)
end stage renal disease  (ISO)
endomyocardial fibrosis  (ISO)
eosinophilic esophagitis  (ISO)
epilepsy  (ISO)
essential thrombocythemia  (ISO)
Experimental Arthritis  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
Experimental Liver Neoplasms  (ISO)
Experimental Mammary Neoplasms  (ISO)
extrahepatic cholestasis  (ISO)
factor VIII deficiency  (ISO)
familial hyperlipidemia  (ISO)
Fibrosis  (ISO)
focal segmental glomerulosclerosis  (ISO)
Gallbladder Neoplasms  (ISO)
genetic disease  (ISO)
gout  (ISO)
Graves' disease  (ISO)
heart disease  (ISO)
Heart Injuries  (ISO)
Hemorrhagic Shock  (ISO)
hepatic encephalopathy  (ISO)
Hepatic Insufficiency  (ISO)
hepatocellular carcinoma  (ISO)
Hepatomegaly  (ISO)
Hereditary Hemorrhagic Telangiectasia, Type 1  (ISO)
Hyperoxia  (ISO)
Hyperplasia  (ISO)
hypertension  (ISO)
hypertrophic cardiomyopathy  (ISO)
hyperuricemia  (ISO)
IgA glomerulonephritis  (ISO)
impotence  (ISO)
Infant, Newborn, Diseases  (ISO)
Inflammation  (ISO)
inflammatory bowel disease  (ISO)
INFLAMMATORY BOWEL DISEASE, IMMUNODEFICIENCY, AND ENCEPHALOPATHY  (ISO)
insulinoma  (ISO)
interstitial lung disease  (ISO)
Joubert syndrome 1  (ISO)
kidney disease  (ISO)
Kidney Reperfusion Injury  (ISO)
liver cirrhosis  (ISO)
localized scleroderma  (ISO)
lung disease  (ISO)
Lung Neoplasms  (ISO)
Lymphomatoid Papulosis  (ISO)
maple syrup urine disease  (ISO)
Meckel Syndrome 10  (ISO)
metabolic dysfunction and alcohol associated liver disease  (ISO)
metabolic dysfunction-associated steatotic liver disease  (ISO)
Metabolic Syndrome  (ISO)
middle cerebral artery infarction  (ISO)
multiple myeloma  (ISO)
muscular disease  (ISO)
myelofibrosis  (ISO)
myocardial infarction  (ISO)
Myocardial Reperfusion Injury  (ISO)
Nasal Polyps  (ISO)
Neoplasm Invasiveness  (ISO)
Neoplasm Metastasis  (ISO)
Neoplastic Cell Transformation  (ISO)
nephrolithiasis  (ISO)
nephrosclerosis  (ISO)
nephrotic syndrome  (ISO)
nephrotoxicity  (ISO)
Neuralgia  (ISO)
obesity  (ISO)
occupational asthma  (ISO)
Occupational Diseases  (ISO)
oral submucous fibrosis  (ISO)
osteoarthritis  (ISO)
osteochondrodysplasia  (ISO)
osteoporosis  (ISO)
pancreatic cancer  (ISO)
pancreatic ductal adenocarcinoma  (ISO)
pancreatic ductal carcinoma  (ISO)
papilloma  (ISO)
Paraquat Lung  (ISO)
Peritoneal Fibrosis  (ISO)
Peyronie's disease  (ISO)
pleural disease  (ISO)
pneumonia  (ISO)
Posterior Leukoencephalopathy Syndrome  (ISO)
Postmenopausal Osteoporosis  (ISO)
primary biliary cholangitis  (ISO)
Progressive Diaphyseal Dysplasia 1  (ISO)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
proteinuria  (ISO)
psoriasis  (ISO)
pulmonary emphysema  (ISO)
pulmonary fibrosis  (ISO)
pulmonary hypertension  (ISO)
pulmonary sarcoidosis  (ISO)
Radiation Pneumonitis  (ISO)
renal cell carcinoma  (ISO)
rhinitis  (ISO)
Right Ventricular Hypertrophy  (ISO)
sarcoidosis  (ISO)
Sepsis  (ISO)
severe acute respiratory syndrome  (ISO)
sickle cell anemia  (ISO)
Sjogren's syndrome  (ISO)
Skin Neoplasms  (ISO)
Spinal Cord Injuries  (ISO)
Spontaneous Abortions  (ISO)
Spontaneous Neoplasm Regression  (ISO)
squamous cell carcinoma  (ISO)
Stroke  (ISO)
thrombocytopenia  (ISO)
tracheal stenosis  (ISO)
traumatic brain injury  (ISO)
Tubulointerstitial Fibrosis  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
uremia  (ISO)
ureteral obstruction  (ISO)
urethral obstruction  (ISO)
urticaria  (ISO)
uveitis  (ISO)
Ventricular Remodeling  (ISO)
vitiligo  (ISO)
Wallerian Degeneration  (ISO)
Wounds and Injuries  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains  (ISO)
animal organ regeneration  (ISO)
aortic valve morphogenesis  (ISO)
apoptotic process  (ISO)
ATP biosynthetic process  (ISO)
branch elongation involved in mammary gland duct branching  (ISO)
bronchiole development  (ISO)
canonical Wnt signaling pathway  (ISO)
cell activation  (ISO)
cell morphogenesis  (ISO)
cell population proliferation  (ISO)
cell projection organization  (IEA)
cell-cell junction organization  (ISO)
cellular response to acetaldehyde  (ISO)
cellular response to dexamethasone stimulus  (ISO)
cellular response to glucose stimulus  (ISO)
cellular response to growth factor stimulus  (ISO)
cellular response to hypoxia  (ISO)
cellular response to insulin-like growth factor stimulus  (ISO)
cellular response to ionizing radiation  (ISO)
cellular response to low-density lipoprotein particle stimulus  (ISO)
cellular response to mechanical stimulus  (ISO)
cellular response to platelet-derived growth factor stimulus  (ISO)
cellular response to transforming growth factor beta stimulus  (ISO)
cellular response to virus  (ISO)
chondrocyte differentiation  (ISO)
columnar/cuboidal epithelial cell maturation  (ISO)
connective tissue development  (ISO)
defense response to fungus  (ISO)
digestive tract development  (ISO)
embryonic liver development  (ISO)
endoderm development  (ISO)
epithelial cell proliferation  (ISO)
epithelial to mesenchymal transition  (ISO)
extracellular matrix assembly  (ISO)
extrinsic apoptotic signaling pathway  (ISO)
face morphogenesis  (ISO)
female pregnancy  (ISO)
frontal suture morphogenesis  (ISO)
gene expression  (ISO)
germ cell migration  (ISO)
heart development  (ISO)
heart valve morphogenesis  (ISO)
hematopoietic progenitor cell differentiation  (ISO)
hyaluronan catabolic process  (ISO)
inflammatory response  (ISO)
inner ear development  (ISO)
intracellular calcium ion homeostasis  (ISO)
Langerhans cell differentiation  (ISO)
lens fiber cell differentiation  (ISO)
liver regeneration  (ISO)
lung alveolus development  (ISO)
lymph node development  (ISO)
mammary gland branching involved in thelarche  (ISO)
mammary gland development  (ISO)
membrane protein intracellular domain proteolysis  (ISO)
mononuclear cell proliferation  (ISO)
morphogenesis of a branching structure  (ISO)
muscle cell cellular homeostasis  (ISO)
myelination  (ISO)
negative regulation of biomineral tissue development  (ISO)
negative regulation of blood vessel endothelial cell migration  (ISO)
negative regulation of cell cycle  (ISO)
negative regulation of cell differentiation  (ISO)
negative regulation of cell growth  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of cell-cell adhesion mediated by cadherin  (ISO)
negative regulation of DNA-templated transcription  (ISO)
negative regulation of epithelial cell proliferation  (ISO)
negative regulation of fat cell differentiation  (ISO)
negative regulation of gene expression  (ISO)
negative regulation of hyaluronan biosynthetic process  (ISO)
negative regulation of interleukin-17 production  (ISO)
negative regulation of macrophage cytokine production  (ISO)
negative regulation of miRNA transcription  (ISO)
negative regulation of myoblast differentiation  (ISO)
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target  (ISO)
negative regulation of neuroblast proliferation  (ISO)
negative regulation of ossification  (ISO)
negative regulation of phagocytosis  (ISO)
negative regulation of protein localization to plasma membrane  (ISO)
negative regulation of release of sequestered calcium ion into cytosol  (ISO)
negative regulation of skeletal muscle tissue development  (ISO)
negative regulation of T cell activation  (ISO)
negative regulation of T cell proliferation  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
neural tube closure  (ISO)
neural tube development  (ISO)
neuron apoptotic process  (ISO)
Notch signaling pathway  (ISO)
odontoblast differentiation  (ISO)
odontogenesis of dentin-containing tooth  (ISO)
oligodendrocyte development  (ISO)
osteoclast differentiation  (ISO)
phosphate-containing compound metabolic process  (ISO)
phospholipid homeostasis  (ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of blood vessel endothelial cell migration  (ISO)
positive regulation of branching involved in ureteric bud morphogenesis  (ISO)
positive regulation of canonical NF-kappaB signal transduction  (ISO)
positive regulation of canonical Wnt signaling pathway  (ISO)
positive regulation of cardiac muscle cell differentiation  (ISO)
positive regulation of cell migration  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of chemokine (C-X-C motif) ligand 2 production  (ISO)
positive regulation of chemotaxis  (ISO)
positive regulation of collagen biosynthetic process  (ISO)
positive regulation of DNA-templated transcription  (ISO)
positive regulation of endothelial cell apoptotic process  (ISO)
positive regulation of epidermal growth factor receptor signaling pathway  (ISO)
positive regulation of epithelial cell proliferation  (ISO)
positive regulation of epithelial to mesenchymal transition  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of exit from mitosis  (ISO)
positive regulation of extracellular matrix assembly  (ISO)
positive regulation of fibroblast migration  (ISO)
positive regulation of fibroblast proliferation  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of inflammatory response  (ISO)
positive regulation of interleukin-17 production  (ISO)
positive regulation of interleukin-6 production  (ISO)
positive regulation of isotype switching to IgA isotypes  (ISO)
positive regulation of MAPK cascade  (ISO)
positive regulation of mesenchymal stem cell proliferation  (ISO)
positive regulation of microglia differentiation  (ISO)
positive regulation of miRNA transcription  (ISO)
positive regulation of mononuclear cell migration  (ISO)
positive regulation of NF-kappaB transcription factor activity  (ISO)
positive regulation of odontogenesis  (ISO)
positive regulation of peptidyl-tyrosine phosphorylation  (ISO)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (ISO)
positive regulation of primary miRNA processing  (ISO)
positive regulation of protein import into nucleus  (ISO)
positive regulation of protein localization to nucleus  (ISO)
positive regulation of protein metabolic process  (ISO)
positive regulation of protein secretion  (ISO)
positive regulation of protein-containing complex assembly  (ISO)
positive regulation of receptor signaling pathway via STAT  (ISO)
positive regulation of regulatory T cell differentiation  (ISO)
positive regulation of SMAD protein signal transduction  (ISO)
positive regulation of smooth muscle cell differentiation  (ISO)
positive regulation of smooth muscle cell proliferation  (ISO)
positive regulation of stem cell proliferation  (ISO)
positive regulation of superoxide anion generation  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of tumor necrosis factor production  (ISO)
positive regulation of vascular permeability  (ISO)
positive regulation of vasculature development  (ISO)
protein export from nucleus  (ISO)
protein phosphorylation  (ISO)
receptor catabolic process  (ISO)
regulation of actin cytoskeleton organization  (ISO)
regulation of branching involved in mammary gland duct morphogenesis  (ISO)
regulation of cartilage development  (ISO)
regulation of cell cycle  (ISO)
regulation of cell population proliferation  (ISO)
regulation of enamel mineralization  (ISO)
regulation of epithelial to mesenchymal transition involved in endocardial cushion formation  (ISO)
regulation of gene expression  (ISO)
regulation of interleukin-23 production  (ISO)
regulation of miRNA transcription  (ISO)
regulation of protein import into nucleus  (ISO)
regulation of regulatory T cell differentiation  (ISO)
regulation of sodium ion transport  (ISO)
regulation of striated muscle tissue development  (ISO)
regulatory T cell differentiation  (ISO)
response to cholesterol  (ISO)
response to estradiol  (ISO)
response to ethanol  (ISO)
response to gamma radiation  (ISO)
response to glucose  (ISO)
response to hypoxia  (ISO)
response to immobilization stress  (ISO)
response to laminar fluid shear stress  (ISO)
response to progesterone  (ISO)
response to salt  (ISO)
response to vitamin D  (ISO)
response to wounding  (ISO)
response to xenobiotic stimulus  (ISO)
retina vasculature development in camera-type eye  (ISO)
salivary gland morphogenesis  (ISO)
signal transduction  (IEA)
sprouting angiogenesis  (ISO)
stem cell proliferation  (ISO)
surfactant homeostasis  (ISO)
T cell activation  (ISO)
T cell differentiation  (ISO)
T cell homeostasis  (ISO)
T cell proliferation  (ISO)
tolerance induction to self antigen  (ISO)
transforming growth factor beta receptor signaling pathway  (ISO)
ureteric bud development  (ISO)
vasculogenesis  (ISO)
ventricular cardiac muscle tissue morphogenesis  (ISO)

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
B9D2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11112,621,832 - 112,627,726 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1112,621,633 - 112,643,885 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1112,025,951 - 112,032,055 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01113,219,930 - 113,226,035 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1113,219,701 - 113,241,694 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11112,781,179 - 112,787,278 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01112,413,522 - 112,419,614 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01113,406,803 - 113,412,909 (+)NCBIUU_Cfam_GSD_1.0
TGFB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381941,330,323 - 41,353,922 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1941,301,587 - 41,353,922 (-)EnsemblGRCh38hg38GRCh38
GRCh371941,836,228 - 41,859,827 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361946,528,491 - 46,551,656 (-)NCBINCBI36Build 36hg18NCBI36
Build 341946,528,658 - 46,551,158NCBI
Celera1938,636,964 - 38,659,992 (-)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1938,268,902 - 38,291,920 (-)NCBIHuRef
CHM1_11941,836,504 - 41,859,495 (-)NCBICHM1_1
T2T-CHM13v2.01944,151,181 - 44,174,790 (-)NCBIT2T-CHM13v2.0
Tgfb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39725,386,406 - 25,404,503 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl725,386,427 - 25,404,502 (+)EnsemblGRCm39 Ensembl
GRCm38725,687,002 - 25,705,077 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl725,687,002 - 25,705,077 (+)EnsemblGRCm38mm10GRCm38
MGSCv37726,472,021 - 26,490,015 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36725,395,762 - 25,413,756 (+)NCBIMGSCv36mm8
Celera720,295,914 - 20,313,908 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map713.98NCBI
Tgfb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8190,324,312 - 90,340,627 (+)NCBIGRCr8
mRatBN7.2181,196,532 - 81,212,848 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl181,196,532 - 81,212,847 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx186,588,717 - 86,605,032 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0195,140,207 - 95,156,569 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0188,344,513 - 88,360,828 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0182,480,875 - 82,497,196 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl182,480,195 - 82,497,199 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0183,742,151 - 83,758,472 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4180,894,705 - 80,911,020 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1180,972,549 - 80,988,992 (+)NCBI
Celera175,636,001 - 75,652,315 (+)NCBICelera
Cytogenetic Map1q21NCBI
Tgfb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955555270,652 - 288,441 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955555274,405 - 288,441 (-)NCBIChiLan1.0ChiLan1.0
TGFB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22047,541,048 - 47,564,105 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11949,409,816 - 49,432,810 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01938,324,009 - 38,347,003 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11946,831,659 - 46,852,973 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1946,831,659 - 46,852,973 (-)Ensemblpanpan1.1panPan2
Tgfb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934915,314,010 - 15,330,197 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366613,742,066 - 3,758,272 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366613,742,080 - 3,758,266 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TGFB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl649,332,173 - 49,349,046 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1649,332,169 - 49,348,642 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2645,127,027 - 45,141,968 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap6q11-q21NCBI
TGFB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1635,651,583 - 35,674,387 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl635,648,677 - 35,674,365 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607313,886,646 - 13,908,666 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tgfb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624907161,569 - 176,605 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624907162,567 - 175,696 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in B9D2
55 total Variants

Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005616543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005616544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038468070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038468071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038468072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038528807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038528808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038528809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038593080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038593081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038593082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038656897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038656898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038656899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_533658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: XM_005616543   ⟹   XP_005616600
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11112,622,205 - 112,627,726 (+)NCBI
Dog10K_Boxer_Tasha1112,026,311 - 112,032,055 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005616544   ⟹   XP_005616601
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11112,621,832 - 112,627,726 (+)NCBI
Dog10K_Boxer_Tasha1112,025,951 - 112,032,055 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038468070   ⟹   XP_038323998
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11112,781,539 - 112,787,278 (+)NCBI
RefSeq Acc Id: XM_038468071   ⟹   XP_038323999
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11112,781,179 - 112,787,278 (+)NCBI
RefSeq Acc Id: XM_038468072   ⟹   XP_038324000
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11112,781,179 - 112,787,278 (+)NCBI
RefSeq Acc Id: XM_038528807   ⟹   XP_038384735
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01113,407,163 - 113,412,909 (+)NCBI
RefSeq Acc Id: XM_038528808   ⟹   XP_038384736
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01113,406,803 - 113,412,909 (+)NCBI
RefSeq Acc Id: XM_038528809   ⟹   XP_038384737
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01113,406,803 - 113,412,909 (+)NCBI
RefSeq Acc Id: XM_038593080   ⟹   XP_038449008
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01112,413,882 - 112,419,614 (+)NCBI
RefSeq Acc Id: XM_038593081   ⟹   XP_038449009
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01112,413,522 - 112,419,614 (+)NCBI
RefSeq Acc Id: XM_038593082   ⟹   XP_038449010
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01112,413,522 - 112,419,614 (+)NCBI
RefSeq Acc Id: XM_038656897   ⟹   XP_038512825
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01113,220,290 - 113,226,035 (+)NCBI
RefSeq Acc Id: XM_038656898   ⟹   XP_038512826
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01113,219,930 - 113,226,035 (+)NCBI
RefSeq Acc Id: XM_038656899   ⟹   XP_038512827
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01113,219,930 - 113,226,035 (+)NCBI
RefSeq Acc Id: XM_533658   ⟹   XP_533658
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11112,621,835 - 112,627,726 (+)NCBI
Dog10K_Boxer_Tasha1112,025,951 - 112,032,055 (+)NCBI
Sequence:
RefSeq Acc Id: XP_005616601   ⟸   XM_005616544
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M6E3 (UniProtKB/TrEMBL),   A0A8C0KM44 (UniProtKB/TrEMBL),   A0A8I3N1Y5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_533658   ⟸   XM_533658
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M6E3 (UniProtKB/TrEMBL),   A0A8C0KM44 (UniProtKB/TrEMBL),   A0A8I3N1Y5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005616600   ⟸   XM_005616543
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_038323999   ⟸   XM_038468071
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038324000   ⟸   XM_038468072
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038323998   ⟸   XM_038468070
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038449009   ⟸   XM_038593081
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038449010   ⟸   XM_038593082
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038449008   ⟸   XM_038593080
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038512826   ⟸   XM_038656898
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M6E3 (UniProtKB/TrEMBL),   A0A8C0KM44 (UniProtKB/TrEMBL),   A0A8I3N1Y5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038512827   ⟸   XM_038656899
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M6E3 (UniProtKB/TrEMBL),   A0A8C0KM44 (UniProtKB/TrEMBL),   A0A8I3N1Y5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038512825   ⟸   XM_038656897
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038384736   ⟸   XM_038528808
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KM44 (UniProtKB/TrEMBL),   A0A8C0M6E3 (UniProtKB/TrEMBL),   A0A8I3N1Y5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038384737   ⟸   XM_038528809
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KM44 (UniProtKB/TrEMBL),   A0A8C0M6E3 (UniProtKB/TrEMBL),   A0A8I3N1Y5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038384735   ⟸   XM_038528807
- Peptide Label: isoform X1
Protein Domains
TGF-beta family profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000005014 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030002746 UniProtKB/TrEMBL
  ENSCAFG00040008564 UniProtKB/TrEMBL
  ENSCAFG00845002395 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000037002.5 UniProtKB/TrEMBL
  ENSCAFT00000043918.3 UniProtKB/TrEMBL
  ENSCAFT00030005160.1 UniProtKB/TrEMBL
  ENSCAFT00040015984.1 UniProtKB/TrEMBL
  ENSCAFT00845004222.1 UniProtKB/TrEMBL
  ENSCAFT00845004228 ENTREZGENE
  ENSCAFT00845004228.1 UniProtKB/TrEMBL
  ENSCAFT00845004249.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.90.10 UniProtKB/TrEMBL
  2.60.120.970 UniProtKB/TrEMBL
InterPro C2_B9-type_dom UniProtKB/TrEMBL
  Cystine-knot_cytokine UniProtKB/TrEMBL
  TGF-b_C UniProtKB/TrEMBL
  TGF-b_propeptide UniProtKB/TrEMBL
  TGF-beta-rel UniProtKB/TrEMBL
  TGFb1 UniProtKB/TrEMBL
  TGFb_CS UniProtKB/TrEMBL
NCBI Gene B9D2 ENTREZGENE
PANTHER B9 DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
  PTHR11848 UniProtKB/TrEMBL
  PTHR12968 UniProtKB/TrEMBL
  TRANSFORMING GROWTH FACTOR BETA-1 PROPROTEIN UniProtKB/TrEMBL
Pfam B9-C2 UniProtKB/TrEMBL
  TGF_beta UniProtKB/TrEMBL
  TGFb_propeptide UniProtKB/TrEMBL
PRINTS TGFBETA1 UniProtKB/TrEMBL
PROSITE C2_B9 UniProtKB/TrEMBL
  TGF_BETA_1 UniProtKB/TrEMBL
  TGF_BETA_2 UniProtKB/TrEMBL
SMART TGFB UniProtKB/TrEMBL
Superfamily-SCOP SSF57501 UniProtKB/TrEMBL
UniProt A0A8C0KM44 ENTREZGENE
  A0A8C0M6E3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MMV5_CANLF UniProtKB/TrEMBL
  A0A8I3N1Y5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RQP1_CANLF UniProtKB/TrEMBL
  A0A8P0SPW7_CANLF UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-08-15 B9D2  B9 domain containing 2    B9 protein domain 2  Symbol and/or name change 5135510 APPROVED