MIR455 (microRNA 455) - Rat Genome Database

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Gene: MIR455 (microRNA 455) Homo sapiens
Analyze
Symbol: MIR455
Name: microRNA 455
RGD ID: 1604864
HGNC Page HGNC
Description: Predicted to act upstream of or within several processes, including cellular response to amino acid stimulus; cellular response to leukemia inhibitory factor; and sensory perception of sound. Predicted to be part of RISC complex.
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: hsa-mir-455; mir-455; MIRN455
RGD Orthologs
Mouse
Rat
Dog
Pig
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl9114,209,434 - 114,209,529 (+)EnsemblGRCh38hg38GRCh38
GRCh389114,209,434 - 114,209,529 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379116,971,714 - 116,971,809 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369116,011,534 - 116,011,629 (+)NCBINCBI36hg18NCBI36
Celera987,619,629 - 87,619,724 (+)NCBI
Cytogenetic Map9q32NCBI
HuRef986,578,236 - 86,578,331 (+)NCBIHuRef
CHM1_19117,118,235 - 117,118,330 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
RISC complex  (ISO)

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15652478   PMID:16381832   PMID:17604727   PMID:17616659   PMID:21037258   PMID:23685355   PMID:25100943   PMID:25188518   PMID:25355599   PMID:25686251   PMID:25916817   PMID:26801503  
PMID:27235675   PMID:27451075   PMID:27625077   PMID:27638301   PMID:27748890   PMID:27861461   PMID:28038450   PMID:28300591   PMID:28350134   PMID:28440508   PMID:28535014   PMID:28538837  
PMID:28633632   PMID:28714005   PMID:28770965   PMID:28934394   PMID:29039517   PMID:29170127   PMID:29257232   PMID:29518510   PMID:29615149   PMID:29748607   PMID:29932921   PMID:30048472  
PMID:30132981   PMID:30193773   PMID:30310937   PMID:30444038   PMID:30584669   PMID:30609030   PMID:30838724   PMID:30858037   PMID:30898696   PMID:31181293   PMID:31197461   PMID:31237446  
PMID:31492753   PMID:31509024   PMID:31524168   PMID:31638263   PMID:31732382   PMID:31763681   PMID:31809639   PMID:31828845   PMID:31973730   PMID:32163390   PMID:32272865   PMID:32343998  
PMID:32413267   PMID:32478495   PMID:32574796   PMID:32584608   PMID:32838807   PMID:32841775   PMID:32879124   PMID:32918360   PMID:33008443   PMID:33040830   PMID:33057072   PMID:33311443  
PMID:33412267   PMID:33495816   PMID:33708992  


Genomics

Comparative Map Data
MIR455
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl9114,209,434 - 114,209,529 (+)EnsemblGRCh38hg38GRCh38
GRCh389114,209,434 - 114,209,529 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379116,971,714 - 116,971,809 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369116,011,534 - 116,011,629 (+)NCBINCBI36hg18NCBI36
Celera987,619,629 - 87,619,724 (+)NCBI
Cytogenetic Map9q32NCBI
HuRef986,578,236 - 86,578,331 (+)NCBIHuRef
CHM1_19117,118,235 - 117,118,330 (+)NCBICHM1_1
Mir455
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39463,175,088 - 63,175,169 (+)NCBIGRCm39mm39
GRCm39 Ensembl463,175,088 - 63,175,169 (+)Ensembl
GRCm38463,256,851 - 63,256,932 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl463,256,851 - 63,256,932 (+)EnsemblGRCm38mm10GRCm38
MGSCv37462,917,885 - 62,917,966 (+)NCBIGRCm37mm9NCBIm37
Celera461,913,734 - 61,913,815 (+)NCBICelera
Cytogenetic Map4B3NCBI
Mir455
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2576,689,313 - 76,689,390 (+)NCBImRatBN7.2
Rnor_6.0 Ensembl579,097,208 - 79,097,285 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0579,097,208 - 79,097,285 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0583,211,456 - 83,211,533 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera575,623,186 - 75,623,263 (+)NCBICelera
Cytogenetic Map5q24NCBI
MIR455
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11168,461,911 - 68,461,968 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1168,461,896 - 68,461,983 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1166,864,258 - 66,864,315 (+)NCBI
ROS_Cfam_1.01169,585,477 - 69,585,534 (+)NCBI
UMICH_Zoey_3.11168,101,107 - 68,101,164 (+)NCBI
UNSW_CanFamBas_1.01168,132,141 - 68,132,198 (+)NCBI
UU_Cfam_GSD_1.01168,871,375 - 68,871,432 (+)NCBI
MIR455
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1254,824,196 - 254,824,291 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11254,824,200 - 254,824,279 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21286,017,379 - 286,017,458 (+)NCBISscrofa10.2Sscrofa10.2susScr3

miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
ROPN1Bhsa-miR-455-3pMirtarbaseexternal_infoCLASHFunctional MTI (Weak)23622248
TRIM23hsa-miR-455-5pMirtarbaseexternal_infoCLASHFunctional MTI (Weak)23622248

Predicted Targets
Summary Value
Count of predictions:31773
Count of gene targets:13608
Count of transcripts:26972
Interacting mature miRNAs:hsa-miR-455-3p, hsa-miR-455-5p
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 1 1 1 1 1 1
Low 36 31 70 50 20 50 81 19 85 56 81 61 4 11 45 2
Below cutoff 70 70 57 26 24 23 100 51 94 24 53 45 3 37 58

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000384993
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl9114,209,434 - 114,209,529 (+)Ensembl
RefSeq Acc Id: NR_030255
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh389114,209,434 - 114,209,529 (+)NCBI
GRCh379116,971,714 - 116,971,809 (+)RGD
Celera987,619,629 - 87,619,724 (+)RGD
HuRef986,578,236 - 86,578,331 (+)ENTREZGENE
CHM1_19117,118,235 - 117,118,330 (+)NCBI
Sequence:

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 9p24.3-q34.3(chr9:204193-138179445) copy number gain See cases [RCV000133791] Chr9:204193..138179445 [GRCh38]
Chr9:204193..141073897 [GRCh37]
Chr9:194193..140193718 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138124524)x3 copy number gain See cases [RCV000138783] Chr9:193412..138124524 [GRCh38]
Chr9:204090..141018976 [GRCh37]
Chr9:194090..140138797 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138159073)x3 copy number gain See cases [RCV000138962] Chr9:193412..138159073 [GRCh38]
Chr9:204104..141053525 [GRCh37]
Chr9:194104..140173346 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic|conflicting data from submitters
GRCh38/hg38 9p11.2-q34.3(chr9:193412-138159073)x3 copy number gain See cases [RCV000139207] Chr9:193412..138159073 [GRCh38]
Chr9:68420641..141053525 [GRCh37]
Chr9:67910461..140173346 [NCBI36]
Chr9:9p11.2-q34.3
pathogenic
GRCh38/hg38 9q31.2-33.1(chr9:107530314-117965944)x1 copy number loss See cases [RCV000140794] Chr9:107530314..117965944 [GRCh38]
Chr9:110292595..120728222 [GRCh37]
Chr9:109332416..119768043 [NCBI36]
Chr9:9q31.2-33.1
pathogenic
GRCh38/hg38 9q32(chr9:114193726-114677465)x3 copy number gain See cases [RCV000140795] Chr9:114193726..114677465 [GRCh38]
Chr9:116956006..117439745 [GRCh37]
Chr9:115995827..116479566 [NCBI36]
Chr9:9q32
benign
GRCh38/hg38 9p24.3-q34.3(chr9:203861-138125937)x3 copy number gain See cases [RCV000141876] Chr9:203861..138125937 [GRCh38]
Chr9:203861..141020389 [GRCh37]
Chr9:193861..140140210 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:203862-138125937)x3 copy number gain See cases [RCV000143476] Chr9:203862..138125937 [GRCh38]
Chr9:203862..141020389 [GRCh37]
Chr9:193862..140140210 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh38/hg38 9q22.33-33.1(chr9:99138048-115011033)x1 copy number loss See cases [RCV000148264] Chr9:99138048..115011033 [GRCh38]
Chr9:101900330..117773312 [GRCh37]
Chr9:100940151..116813133 [NCBI36]
Chr9:9q22.33-33.1
pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138179445)x3 copy number gain See cases [RCV000148113] Chr9:193412..138179445 [GRCh38]
Chr9:204193..141073897 [GRCh37]
Chr9:194193..140193718 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh38/hg38 9q22.33-33.1(chr9:99138048-115011033)x1 copy number loss See cases [RCV000050315] Chr9:99138048..115011033 [GRCh38]
Chr9:101900330..117773312 [GRCh37]
Chr9:100940151..116813133 [NCBI36]
Chr9:9q22.33-33.1
pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138179445)x3 copy number gain See cases [RCV000050348] Chr9:193412..138179445 [GRCh38]
Chr9:204193..141073897 [GRCh37]
Chr9:194193..140193718 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh38/hg38 9q22.33-33.1(chr9:99349916-115767475)x1 copy number loss See cases [RCV000052921] Chr9:99349916..115767475 [GRCh38]
Chr9:102112198..118529754 [GRCh37]
Chr9:101152019..117569575 [NCBI36]
Chr9:9q22.33-33.1
pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138124532)x3 copy number gain See cases [RCV000053745] Chr9:193412..138124532 [GRCh38]
Chr9:204193..141018984 [GRCh37]
Chr9:194193..140138805 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138114463)x3 copy number gain See cases [RCV000053746] Chr9:193412..138114463 [GRCh38]
Chr9:214367..141008915 [GRCh37]
Chr9:204367..140128736 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138179445)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053748]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053748]|See cases [RCV000053748] Chr9:193412..138179445 [GRCh38]
Chr9:266045..141073897 [GRCh37]
Chr9:256045..140193718 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:32344 AgrOrtholog
COSMIC MIR455 COSMIC
Ensembl Genes ENSG00000207726 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000384993 ENTREZGENE
GTEx ENSG00000207726 GTEx
HGNC ID HGNC:32344 ENTREZGENE
Human Proteome Map MIR455 Human Proteome Map
miRBase MI0003513 ENTREZGENE
NCBI Gene 619556 ENTREZGENE
PharmGKB PA164722727 PharmGKB
RNAcentral URS00000AD002 RNACentral
  URS000022A78C RNACentral
  URS000075AC6B RNACentral