IL27 (interleukin 27) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: IL27 (interleukin 27) Canis lupus familiaris
Analyze
Symbol: IL27
Name: interleukin 27
RGD ID: 12283377
Description: ENCODES a protein that exhibits interleukin-27 receptor binding (inferred); signaling receptor binding (inferred); INVOLVED IN positive regulation of defense response to virus by host (ortholog); regulation of T cell proliferation (ortholog); response to bacterium (ortholog); PARTICIPATES IN interleukin-27 signaling pathway; ASSOCIATED WITH Acute-On-Chronic Liver Failure (ortholog); Arenaviridae infectious disease (ortholog); asthma (ortholog); FOUND IN cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: interleukin-27 subunit alpha
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1618,243,988 - 18,248,369 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl618,244,040 - 18,247,635 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha619,822,685 - 19,827,046 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0618,380,027 - 18,384,391 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl618,380,086 - 18,384,093 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1618,179,035 - 18,183,396 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0618,094,139 - 18,098,496 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0618,410,212 - 18,414,571 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
IL27
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1618,243,988 - 18,248,369 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl618,244,040 - 18,247,635 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha619,822,685 - 19,827,046 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0618,380,027 - 18,384,391 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl618,380,086 - 18,384,093 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1618,179,035 - 18,183,396 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0618,094,139 - 18,098,496 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0618,410,212 - 18,414,571 (+)NCBIUU_Cfam_GSD_1.0
IL27
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381628,499,362 - 28,506,834 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1628,499,362 - 28,512,051 (-)EnsemblGRCh38hg38GRCh38
GRCh371628,510,683 - 28,518,155 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361628,418,184 - 28,425,656 (-)NCBINCBI36Build 36hg18NCBI36
Build 341628,418,472 - 28,425,633NCBI
Celera1627,685,614 - 27,693,084 (+)NCBICelera
Cytogenetic Map16p12.1-p11.2NCBI
HuRef1626,536,601 - 26,544,073 (-)NCBIHuRef
CHM1_11629,522,293 - 29,529,765 (-)NCBICHM1_1
T2T-CHM13v2.01628,869,090 - 28,896,415 (+)NCBIT2T-CHM13v2.0
Il27
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397126,188,181 - 126,194,197 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7126,188,182 - 126,194,113 (-)EnsemblGRCm39 Ensembl
GRCm387126,589,009 - 126,595,035 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7126,589,010 - 126,594,941 (-)EnsemblGRCm38mm10GRCm38
MGSCv377133,732,809 - 133,738,424 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367126,380,443 - 126,386,058 (-)NCBIMGSCv36mm8
Celera7126,438,423 - 126,444,039 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map769.18NCBI
Il27
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81190,603,684 - 190,609,292 (-)NCBIGRCr8
mRatBN7.21181,173,108 - 181,178,720 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1181,173,372 - 181,178,582 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01198,003,615 - 198,010,112 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1198,003,683 - 198,008,893 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01204,981,789 - 204,987,782 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,730,394 - 185,735,604 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1178,831,320 - 178,837,817 (-)NCBICelera
Cytogenetic Map1q36NCBI
Il27
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554936,712,005 - 6,717,417 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554936,712,005 - 6,717,417 (-)NCBIChiLan1.0ChiLan1.0
IL27
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21831,104,366 - 31,111,861 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11634,982,084 - 34,989,328 (+)NCBINHGRI_mPanPan1
PanPan1.11628,979,717 - 28,984,655 (-)NCBIpanpan1.1PanPan1.1panPan2
Il27
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344123,875,494 - 123,879,941 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650111,973,385 - 11,976,583 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650111,972,715 - 11,978,152 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL27
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl318,421,981 - 18,427,915 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1318,421,962 - 18,427,916 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
IL27
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1526,348,559 - 26,358,028 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl526,348,848 - 26,356,360 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660683,217,584 - 3,222,518 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Il27
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478213,009,564 - 13,015,440 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478213,009,450 - 13,015,548 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in IL27
55 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 4 1 21 22 16 6 6 6 6 22 12 10 9 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022419898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038478682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038478684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038539927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038539928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038543743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038543750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038604008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038604009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038668726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038668727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_844736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000046162   ⟹   ENSCAFP00000036897
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl618,244,040 - 18,247,635 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845004059   ⟹   ENSCAFP00845003246
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl618,380,086 - 18,384,093 (+)Ensembl
RefSeq Acc Id: XM_038478682   ⟹   XP_038334610
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1618,179,306 - 18,183,396 (+)NCBI
RefSeq Acc Id: XM_038478684   ⟹   XP_038334612
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1618,179,035 - 18,183,396 (+)NCBI
RefSeq Acc Id: XM_038539927   ⟹   XP_038395855
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0618,410,480 - 18,414,571 (+)NCBI
RefSeq Acc Id: XM_038539928   ⟹   XP_038395856
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0618,410,212 - 18,414,571 (+)NCBI
RefSeq Acc Id: XM_038543743   ⟹   XP_038399671
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha619,822,953 - 19,827,046 (+)NCBI
RefSeq Acc Id: XM_038543750   ⟹   XP_038399678
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha619,822,685 - 19,827,046 (+)NCBI
RefSeq Acc Id: XM_038604008   ⟹   XP_038459936
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0618,094,407 - 18,098,496 (+)NCBI
RefSeq Acc Id: XM_038604009   ⟹   XP_038459937
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0618,094,139 - 18,098,496 (+)NCBI
RefSeq Acc Id: XM_038668726   ⟹   XP_038524654
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0618,380,295 - 18,384,391 (+)NCBI
RefSeq Acc Id: XM_038668727   ⟹   XP_038524655
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0618,380,027 - 18,384,391 (+)NCBI
Ensembl Acc Id: ENSCAFP00000036897   ⟸   ENSCAFT00000046162
RefSeq Acc Id: XP_038334612   ⟸   XM_038478684
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038334610   ⟸   XM_038478682
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038459937   ⟸   XM_038604009
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038459936   ⟸   XM_038604008
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038524655   ⟸   XM_038668727
- Peptide Label: isoform X2
- UniProtKB: A0A8C0PUD4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038524654   ⟸   XM_038668726
- Peptide Label: isoform X1
- UniProtKB: A0A8C0PUD4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038399678   ⟸   XM_038543750
- Peptide Label: isoform X2
- UniProtKB: A0A8C0PUD4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038399671   ⟸   XM_038543743
- Peptide Label: isoform X1
- UniProtKB: A0A8C0PUD4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038395856   ⟸   XM_038539928
- Peptide Label: isoform X2
- UniProtKB: A0A8C0PUD4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038395855   ⟸   XM_038539927
- Peptide Label: isoform X1
- UniProtKB: A0A8C0PUD4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845003246   ⟸   ENSCAFT00845004059

Promoters
RGD ID:13683637
Promoter ID:EPDNEW_C1703
Type:single initiation site
Name:IL27_1
Description:interleukin 27
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1618,246,131 - 18,246,191EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000017132 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030000719 UniProtKB/TrEMBL
  ENSCAFG00040000408 UniProtKB/TrEMBL
  ENSCAFG00845002305 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000046162.3 UniProtKB/TrEMBL
  ENSCAFT00030001218.1 UniProtKB/TrEMBL
  ENSCAFT00040000685.1 UniProtKB/TrEMBL
  ENSCAFT00845004059 ENTREZGENE
  ENSCAFT00845004059.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.10 UniProtKB/TrEMBL
InterPro 4_helix_cytokine-like_core UniProtKB/TrEMBL
  IL-27_alpha UniProtKB/TrEMBL
NCBI Gene IL27 ENTREZGENE
PANTHER INTERLEUKIN-27 SUBUNIT ALPHA UniProtKB/TrEMBL
  PTHR20879 UniProtKB/TrEMBL
UniProt A0A8C0LXY1_CANLF UniProtKB/TrEMBL
  A0A8C0PUD4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RS44_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:41976 ENTREZGENE