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Gene: CD68 (CD68 molecule) Homo sapiens
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Symbol: CD68
Name: CD68 molecule
Description: Predicted to be involved in several processes, including cellular response to lipopolysaccharide; cellular response to oxidised low-density lipoprotein particle stimulus; and negative regulation of dendritic cell antigen processing and presentation. Predicted to localize to late endosome membrane; lysosomal membrane; and plasma membrane. Biomarker of severe acute respiratory syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD68 antigen; DKFZp686M18236; GP110; LAMP4; macrophage antigen CD68; macrosialin; SCARD1; scavenger receptor class D, member 1
Orthologs:
Mus musculus (house mouse) : Cd68 (CD68 antigen)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cd68 (Cd68 molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd68 (CD68 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD68 (CD68 molecule)
Canis lupus familiaris (dog) : CD68 (CD68 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd68 (CD68 molecule)
Sus scrofa (pig) : CD68 (CD68 molecule)
Chlorocebus sabaeus (African green monkey) : CD68 (CD68 molecule)
Heterocephalus glaber (naked mole-rat) : Cd68 (CD68 molecule)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl177,579,491 - 7,582,111 (+)EnsemblGRCh38hg38GRCh38
GRCh38177,579,638 - 7,582,111 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37177,482,805 - 7,485,429 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,423,529 - 7,426,153 (+)NCBINCBI36hg18NCBI36
Build 34177,423,707 - 7,426,150NCBI
Celera177,509,128 - 7,511,752 (+)NCBI
Cytogenetic Map17p13.1NCBI
HuRef177,376,970 - 7,379,593 (+)NCBIHuRef
CHM1_1177,491,734 - 7,494,362 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on CD68
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1314316
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-08
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.