HLA-DRB1 (major histocompatibility complex, class II, DR beta 1) - Rat Genome Database

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Gene: HLA-DRB1 (major histocompatibility complex, class II, DR beta 1) Homo sapiens
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Symbol: HLA-DRB1
Name: major histocompatibility complex, class II, DR beta 1
RGD ID: 1349823
HGNC Page HGNC:4948
Description: Enables several functions, including MHC class II receptor activity; peptide antigen binding activity; and signaling receptor binding activity. Involved in several processes, including positive regulation of immune response; regulation of gene expression; and regulation of leukocyte differentiation. Located in bounding membrane of organelle; external side of plasma membrane; and immunological synapse. Part of MHC class II protein complex. Implicated in several diseases, including asthma (multiple); autoimmune disease (multiple); bacterial infectious disease (multiple); eye disease (multiple); and sarcoidosis (multiple). Biomarker of toxic shock syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: DR-16; DR-8; DR1; DR16; DR5; DR8; DRB1; DRw10; DRw11; DRw8; DW2.2/DR2.2; FLJ75017; FLJ76359; HLA class II antigen beta chain; HLA class II histocompatibility antigen, DR-1 beta chain; HLA-DR-beta 1; HLA-DR1B; HLA-DRB; HLA-DRB1*; human leucocyte antigen DRB1; leucocyte antigen DR beta 1 chain; leucocyte antigen DRB1; lymphocyte antigen DRB1; major histocompatibility complex, class II, DR beta 1 precursor; MHC class II antigen; MHC class II antigen HLA-DR13; MHC class II HLA-DR beta 1 chain; MHC class II HLA-DR-beta cell surface glycoprotein; MHC class II HLA-DRw10-beta; SS1
RGD Orthologs
Mouse
Rat
Dog
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Is Marker For: QTLs:   MULTSCL5_H   MULTSCL19_H  
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: This gene has been reviewed for its involvement in coronavirus biology, and is locus in the vicinity of disease-associated variant(s).
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38632,578,775 - 32,589,848 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl632,577,902 - 32,589,848 (-)EnsemblGRCh38hg38GRCh38
GRCh37632,546,552 - 32,557,625 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36632,654,527 - 32,665,559 (-)NCBINCBI36Build 36hg18NCBI36
Build 34632,654,526 - 32,665,559NCBI
Cytogenetic Map6p21.32NCBI
CHM1_1632,549,025 - 32,560,089 (-)NCBICHM1_1
T2T-CHM13v2.0632,408,987 - 32,422,414 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
abdominal aortic aneurysm  (IAGP)
Actinic Prurigo  (IAGP)
acute disseminated encephalomyelitis  (IAGP)
Addison's disease  (IAGP)
allergic asthma  (IAGP)
allergic bronchopulmonary aspergillosis  (IAGP)
allergic disease  (EXP,IAGP)
Alport syndrome  (IAGP)
alveolar echinococcosis  (IAGP)
Alzheimer's disease  (IMP)
Amebic Liver Abscess  (IAGP)
angioedema  (EXP)
ankylosing spondylitis  (IAGP)
anti-basement membrane glomerulonephritis  (IAGP)
antiphospholipid syndrome  (IAGP)
aspirin-induced respiratory disease  (IAGP)
asthma  (EXP,IAGP)
atrophic gastritis  (IAGP)
autistic disorder  (EXP,IAGP)
autoimmune disease  (IAGP)
autoimmune hepatitis  (IAGP)
autoimmune polyendocrine syndrome  (IAGP)
autoimmune polyendocrine syndrome type 2  (IAGP)
autoimmune thrombocytopenic purpura  (IAGP)
autoimmune thyroiditis  (IAGP,IMP)
bacterial infectious disease  (IAGP)
Behcet's disease  (IAGP)
berylliosis  (EXP)
breast cancer  (IAGP)
breast carcinoma  (IAGP)
celiac disease  (IAGP)
cerebral infarction  (IAGP)
cervix uteri carcinoma in situ  (IAGP)
Chagas Cardiomyopathy  (IAGP)
Chagas disease  (IAGP)
Chemical and Drug Induced Liver Injury  (EXP)
choreatic disease  (IAGP)
Chronic Hepatitis B  (IAGP)
Chronic Hepatitis C  (IAGP)
cicatricial pemphigoid  (IAGP)
COVID-19  (HEP)
Crohn's disease  (EXP)
cystic echinococcosis  (IAGP)
diabetic angiopathy  (IAGP)
diabetic retinopathy  (IAGP)
drug allergy  (EXP)
End Stage Liver Disease  (IAGP)
endometriosis  (IAGP)
eosinophilia-myalgia syndrome  (EXP)
Experimental Arthritis  (IMP)
Experimental Autoimmune Encephalomyelitis  (IMP)
Experimental Liver Cirrhosis  (ISO)
Germ Cell and Embryonal Neoplasms  (IAGP)
glaucoma  (IAGP)
Graves' disease  (IAGP)
Hantavirus hemorrhagic fever with renal syndrome  (IAGP)
Hashimoto Disease  (IAGP)
Helicobacter Infections  (IAGP)
hepatitis C  (IAGP)
HIV Seropositivity  (IAGP)
human immunodeficiency virus infectious disease  (IAGP)
Human Influenza  (IMP)
hypothyroidism  (IAGP)
Idiopathic Hypersomnolence  (IAGP)
idiopathic pulmonary fibrosis  (IAGP)
infectious mononucleosis  (IAGP)
Juvenile Pauciarticular Chronic Arthritis  (IAGP)
juvenile rheumatoid arthritis  (IAGP)
latex allergy  (IAGP)
leprosy  (IAGP)
liver cirrhosis  (IAGP)
lupus nephritis  (IAGP)
membranous glomerulonephritis  (EXP)
Meniere's disease  (IAGP)
mixed connective tissue disease  (IAGP)
Multibacillary Leprosy  (IAGP)
multidrug-resistant tuberculosis  (IAGP)
multiple sclerosis  (EXP,IAGP)
myasthenia gravis  (IAGP)
Mycobacterium Infections  (IAGP)
myositis  (IAGP)
narcolepsy  (EXP,IAGP)
Nasal Polyps  (IAGP)
nephrotic syndrome  (EXP)
neuromyelitis optica  (IAGP)
non-Hodgkin lymphoma  (EXP)
optic neuritis  (IMP)
Oropharyngeal Neoplasms  (EXP)
Ovarian Neoplasms  (IAGP)
pancreatitis  (EXP)
papillomavirus infectious disease  (IAGP)
paracoccidioidomycosis  (IAGP)
Parkinson's disease  (IAGP)
pemphigus  (IAGP)
peptic ulcer disease  (IAGP)
PERITONEAL GLIOMATOSIS  (IAGP)
Pneumocystis Infections  (ISO)
polyneuropathy  (IAGP)
primary progressive multiple sclerosis  (IAGP)
prostate cancer  (IAGP)
proteasome-associated autoinflammatory syndrome 1  (IAGP)
proteinuria  (EXP)
Pulmonary Atresia  (IAGP)
pulmonary sarcoidosis  (IAGP)
pulmonary tuberculosis  (IAGP)
pure red-cell aplasia  (IAGP)
Recurrent Respiratory Papillomatosis  (IAGP)
renal cell carcinoma  (IAGP)
retinopathy of prematurity  (IAGP)
rheumatic fever  (IAGP)
rheumatic heart disease  (IAGP)
rheumatoid arthritis  (EXP,IAGP)
sarcoidosis  (EXP,IAGP)
schistosomiasis  (IAGP)
schizophrenia  (EXP)
sensorineural hearing loss  (IAGP)
severe acute respiratory syndrome  (IAGP)
Sjogren's syndrome  (IAGP)
Stroke  (IAGP)
Sudden Hearing Loss  (IAGP)
sympathetic ophthalmia  (IAGP)
systemic lupus erythematosus  (EXP,IAGP)
Takayasu's arteritis  (IAGP)
temporal arteritis  (IAGP)
thromboangiitis obliterans  (IAGP)
toxic shock syndrome  (IEP)
Trichiasis  (IAGP)
tuberculosis  (IAGP)
Tubulointerstitial Nephritis and Uveitis  (IAGP)
type 1 diabetes mellitus  (EXP,IAGP)
typhoid fever  (EXP,IAGP)
ulcerative colitis  (EXP)
urticaria  (EXP,IAGP)
Uterine Cervical Neoplasms  (IAGP)
uveitis  (IAGP)
uveoparotid fever  (IAGP)
visceral leishmaniasis  (EXP)
vitiligo  (IAGP)
Vogt-Koyanagi-Harada disease  (IAGP)
vulva cancer  (IAGP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
(S)-nicotine  (EXP)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-hydroxypropanoic acid  (EXP)
3,7-dihydropurine-6-thione  (EXP,ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
acetylsalicylic acid  (EXP)
acrylamide  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (ISO)
amitriptyline  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (EXP)
arsane  (EXP)
arsenic atom  (EXP)
auranofin  (EXP)
azathioprine  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (ISO)
Benzo[k]fluoranthene  (ISO)
beryllium sulfate  (EXP)
bexarotene  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
C60 fullerene  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (EXP,ISO)
cefepime  (EXP)
celecoxib  (EXP)
choline  (ISO)
ciprofloxacin  (EXP)
clindamycin  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
Cuprizon  (ISO)
cyclosporin A  (EXP)
D-penicillamine  (EXP)
decabromodiphenyl ether  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (ISO)
dichloromethane  (ISO)
diclofenac  (EXP)
diethylstilbestrol  (ISO)
diltiazem  (EXP)
diquat  (ISO)
diuron  (ISO)
doxorubicin  (ISO)
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor  (EXP)
epoxiconazole  (ISO)
ethylbenzene  (ISO)
ethylparaben  (EXP)
fenofibrate  (ISO)
ferric oxide  (ISO)
flutamide  (ISO)
fulvestrant  (EXP)
gefitinib  (EXP)
genistein  (ISO)
gentamycin  (ISO)
gold atom  (EXP)
gold(0)  (EXP)
hexachlorobenzene  (ISO)
hydrochlorothiazide  (EXP)
irinotecan  (EXP)
iron atom  (ISO)
iron(0)  (ISO)
isoprenaline  (ISO)
lead(0)  (EXP)
lumiracoxib  (EXP)
mercaptopurine  (EXP,ISO)
metronidazole  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
monosodium L-glutamate  (ISO)
N-(6-acetamidohexyl)acetamide  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
nickel atom  (ISO)
nickel dichloride  (EXP)
nicotine  (EXP)
nitric oxide  (EXP)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
palladium  (EXP)
paracetamol  (EXP)
paraquat  (ISO)
PCB138  (ISO)
perfluorobutyric acid  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (EXP)
purine-6-thiol  (EXP,ISO)
quercetin  (ISO)
rac-lactic acid  (EXP)
S-adenosyl-L-methioninate  (ISO)
S-adenosyl-L-methionine  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
tamoxifen  (EXP,ISO)
temozolomide  (EXP)
testosterone  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
topotecan  (ISO)
tremolite asbestos  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (ISO)
triclosan  (EXP)
triphenyl phosphate  (EXP,ISO)
triptonide  (ISO)
valproic acid  (EXP)
vancomycin  (ISO)
vinclozolin  (ISO)
vorinostat  (ISO)
zoledronic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adaptive immune response  (IEA)
antigen processing and presentation  (IEA)
antigen processing and presentation of endogenous peptide antigen via MHC class II  (IDA)
antigen processing and presentation of exogenous peptide antigen via MHC class II  (IBA,IDA,ISO)
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II  (IEA)
cytoskeleton organization  (IEA)
epidermis development  (TAS)
humoral immune response  (IMP)
immune response  (IDA,IEA,IMP,NAS,TAS)
inflammatory response to antigenic stimulus  (IDA)
macrophage differentiation  (IDA)
myeloid dendritic cell antigen processing and presentation  (IDA)
negative regulation of inflammatory response to antigenic stimulus  (IDA)
negative regulation of T cell proliferation  (IMP)
negative regulation of type II interferon production  (IMP)
peptide antigen assembly with MHC class II protein complex  (IBA,IDA)
positive regulation of canonical NF-kappaB signal transduction  (IDA)
positive regulation of CD4-positive, alpha-beta T cell activation  (IDA)
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation  (IDA)
positive regulation of DNA-templated transcription  (IDA)
positive regulation of ERK1 and ERK2 cascade  (IDA)
positive regulation of immune response  (IBA)
positive regulation of insulin secretion involved in cellular response to glucose stimulus  (IMP)
positive regulation of kinase activity  (IDA)
positive regulation of MAPK cascade  (IDA)
positive regulation of memory T cell differentiation  (IDA)
positive regulation of monocyte differentiation  (IDA)
positive regulation of protein phosphorylation  (IDA)
positive regulation of T cell activation  (IBA)
positive regulation of T cell mediated cytotoxicity  (IDA)
positive regulation of T cell mediated immune response to tumor cell  (IDA)
positive regulation of viral entry into host cell  (IDA)
protein tetramerization  (IDA)
regulation of interleukin-10 production  (IDA)
regulation of interleukin-4 production  (IDA)
regulation of T-helper cell differentiation  (IDA)
response to dexamethasone  (ISO)
signal transduction  (IMP,NAS)
T cell receptor signaling pathway  (IDA)
T-helper 1 type immune response  (IMP)

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Abdominal aortic aneurysm  (IAGP)
Abdominal pain  (IAGP)
Abnormal blistering of the skin  (IAGP)
Abnormal bowel sounds  (IAGP)
Abnormal cardiac ventricular function  (IAGP)
Abnormal cerebrospinal fluid morphology  (IAGP)
Abnormal circulating protein concentration  (IAGP)
Abnormal conjunctiva morphology  (IAGP)
Abnormal liver parenchyma morphology  (IAGP)
Abnormal lung morphology  (IAGP)
Abnormal lymph node morphology  (IAGP)
Abnormal mitral valve morphology  (IAGP)
Abnormal nasal mucosa morphology  (IAGP)
Abnormal peritoneum morphology  (IAGP)
Abnormal pigmentation of the oral mucosa  (IAGP)
Abnormal platelet count  (IAGP)
Abnormal pleura morphology  (IAGP)
Abnormal pulmonary interstitial morphology  (IAGP)
Abnormal pupillary function  (IAGP)
Abnormal rapid eye movement sleep  (IAGP)
Abnormal reproductive system morphology  (IAGP)
Abnormal salivary gland morphology  (IAGP)
Abnormal skin morphology  (IAGP)
Abnormality of connective tissue  (IAGP)
Abnormality of salivation  (IAGP)
Abnormality of skin pigmentation  (IAGP)
Abnormality of T cell physiology  (IAGP)
Abnormality of the adrenal glands  (IAGP)
Abnormality of the gastrointestinal tract  (IAGP)
Abnormality of the musculature  (IAGP)
Abnormality of the skin  (IAGP)
Abnormality of the thyroid gland  (IAGP)
Abnormality of the upper respiratory tract  (IAGP)
Abnormality of thrombocytes  (IAGP)
Adrenocorticotropic hormone excess  (IAGP)
Adult onset  (IAGP)
Alopecia  (IAGP)
Amaurosis fugax  (IAGP)
Anemia  (IAGP)
Anorexia  (IAGP)
Anterior uveitis  (IAGP)
Anti-BP180 antibody positivity  (IAGP)
Anti-BP230 antibody positivity  (IAGP)
Anti-complement component C1q antibody positivity  (IAGP)
Anti-dsDNA antibody positivity  (IAGP)
Anti-La/SS-B antibody positivity  (IAGP)
Anti-nucleoporin 62 antibody positivity  (IAGP)
Anti-phosphatidic acid antibody positivity  (IAGP)
Anti-ribosome Po antibody positivity  (IAGP)
Anti-Ro52/TRIM21 antibody positivity  (IAGP)
Anti-Sm antibody positivity  (IAGP)
Anti-titin antibody positivity  (IAGP)
Anti-U1 ribonucleoprotein antibody positivity  (IAGP)
Antineutrophil antibody positivity  (IAGP)
Antinuclear antibody positivity  (IAGP)
Anxiety  (IAGP)
Aortic dissection  (IAGP)
Arrhythmia  (IAGP)
Arterial thrombosis  (IAGP)
Arteritis  (IAGP)
Arthralgia  (IAGP)
Arthritis  (IAGP)
Asthma  (IAGP)
Ataxia  (IAGP)
Attention deficit hyperactivity disorder  (IAGP)
Atypical behavior  (IAGP)
Autoimmune antibody positivity  (IAGP)
Autoimmunity  (IAGP)
Autosomal dominant inheritance  (IAGP)
Back pain  (IAGP)
Blindness  (IAGP)
Blurred vision  (IAGP)
Bone cyst  (IAGP)
Bradykinesia  (IAGP)
Bronchiectasis  (IAGP)
Carious teeth  (IAGP)
Cataplexy  (IAGP)
Cataract  (IAGP)
Cerebral ischemia  (IAGP)
Cheilitis  (IAGP)
Chest pain  (IAGP)
Chorea  (IAGP)
Chorioretinitis  (IAGP)
Chylothorax  (IAGP)
Clubbing  (IAGP)
CNS demyelination  (IAGP)
Conductive hearing impairment  (IAGP)
Congestive heart failure  (IAGP)
Constipation  (IAGP)
Cough  (IAGP)
Crackles  (IAGP)
Crazy paving pattern  (IAGP)
Cutaneous photosensitivity  (IAGP)
Cyanosis  (IAGP)
Dacryocystitis  (IAGP)
Decreased circulating complement C3 concentration  (IAGP)
Decreased circulating complement C4 concentration  (IAGP)
Decreased circulating cortisol level  (IAGP)
Decreased DLCO  (IAGP)
Decreased liver function  (IAGP)
Depression  (IAGP)
Diabetes insipidus  (IAGP)
Diabetes mellitus  (IAGP)
Diplopia  (IAGP)
Discoid lupus rash  (IAGP)
Double outlet right ventricle with subpulmonary ventricular septal defect without pulmonary stenosis  (IAGP)
Drooling  (IAGP)
Dysarthria  (IAGP)
Dyspareunia  (IAGP)
Dysphagia  (IAGP)
Dyspnea  (IAGP)
Eczematoid dermatitis  (IAGP)
Elevated bronchoalveolar lavage fluid lymphocyte proportion  (IAGP)
Elevated circulating C-reactive protein concentration  (IAGP)
Elevated circulating D-dimer concentration  (IAGP)
Elevated circulating osteopontin level  (IAGP)
Elevated erythrocyte sedimentation rate  (IAGP)
Emotional lability  (IAGP)
Emphysema  (IAGP)
Enlarged lacrimal glands  (IAGP)
Enlargement of parotid gland  (IAGP)
Eosinophilia  (IAGP)
Epiphora  (IAGP)
Epistaxis  (IAGP)
Erythema  (IAGP)
Erythema nodosum  (IAGP)
Excessive daytime somnolence  (IAGP)
Facial palsy  (IAGP)
Fatigue  (IAGP)
Female sexual dysfunction  (IAGP)
Fever  (IAGP)
Flexion contracture  (IAGP)
Foam cells  (IAGP)
Foot joint contracture  (IAGP)
Gangrene  (IAGP)
Gastroesophageal reflux  (IAGP)
Gastrointestinal infarctions  (IAGP)
Generalized lymphadenopathy  (IAGP)
Glaucoma  (IAGP)
Glomerulonephritis  (IAGP)
Glossitis  (IAGP)
Hallucinations  (IAGP)
Headache  (IAGP)
Hearing impairment  (IAGP)
Heart block  (IAGP)
Hematuria  (IAGP)
Hemiplegia  (IAGP)
Hemolytic anemia  (IAGP)
Hemoptysis  (IAGP)
Hepatic failure  (IAGP)
Hepatomegaly  (IAGP)
Hypercalcemia  (IAGP)
Hypercalciuria  (IAGP)
Hyperfibrinogenemia  (IAGP)
Hyperhidrosis  (IAGP)
Hyperpigmentation of the skin  (IAGP)
Hypertension  (IAGP)
Hypertensive crisis  (IAGP)
Hyperthyroidism  (IAGP)
Hypnagogic hallucination  (IAGP)
Hypnopompic hallucination  (IAGP)
Hypopigmentation of the skin  (IAGP)
Hypopigmented skin patches  (IAGP)
Hypothermia  (IAGP)
Hypothyroidism  (IAGP)
Hypoxemia  (IAGP)
Impaired mastication  (IAGP)
Incoordination  (IAGP)
Increased alpha-globulin  (IAGP)
Increased circulating antibody concentration  (IAGP)
Increased circulating IgE concentration  (IAGP)
Increased circulating interleukin 6 concentration  (IAGP)
Increased circulating lactate dehydrogenase concentration  (IAGP)
Increased CSF protein concentration  (IAGP)
Increased T cell count  (IAGP)
Inflammation of the large intestine  (IAGP)
Insomnia  (IAGP)
Intraalveolar phospholipid accumulation  (IAGP)
Iridocyclitis  (IAGP)
Ischemic stroke  (IAGP)
Jaw claudication  (IAGP)
Joint contracture of the hand  (IAGP)
Joint stiffness  (IAGP)
Joint swelling  (IAGP)
Juvenile rheumatoid arthritis  (IAGP)
Keratoconjunctivitis sicca  (IAGP)
Leukopenia  (IAGP)
Livedo reticularis  (IAGP)
Lupus nephritis  (IAGP)
Lymphadenopathy  (IAGP)
Lymphedema  (IAGP)
Lymphoma  (IAGP)
Macule  (IAGP)
Maculopapular exanthema  (IAGP)
Malabsorption  (IAGP)
Malaise  (IAGP)
Malar rash  (IAGP)
Male sexual dysfunction  (IAGP)
Mediastinal lymphadenopathy  (IAGP)
Mediastinal mass  (IAGP)
Meningitis  (IAGP)
Migraine  (IAGP)
Motor conduction block  (IAGP)
Mucosal telangiectasiae  (IAGP)
Muscle weakness  (IAGP)
Myalgia  (IAGP)
Myocarditis  (IAGP)
Myositis  (IAGP)
Narrow foramen obturatorium  (IAGP)
Nasal polyposis  (IAGP)
Nausea and vomiting  (IAGP)
Nephrocalcinosis  (IAGP)
Nephrolithiasis  (IAGP)
Night sweats  (IAGP)
Nocturia  (IAGP)
Non-Mendelian inheritance  (IAGP)
Nonproductive cough  (IAGP)
NREM parasomnia  (IAGP)
Nystagmus  (IAGP)
Obesity  (IAGP)
Oliguria  (IAGP)
Ophthalmoparesis  (IAGP)
Optic atrophy  (IAGP)
Optic neuropathy  (IAGP)
Oral mucosal blisters  (IAGP)
Oral ulcer  (IAGP)
Osteolysis  (IAGP)
Pancytopenia  (IAGP)
Paresthesia  (IAGP)
Parkinsonism  (IAGP)
Parotitis  (IAGP)
Peptic ulcer  (IAGP)
Pericardial effusion  (IAGP)
Pericarditis  (IAGP)
Peripheral neuropathy  (IAGP)
Peritoneal effusion  (IAGP)
Photophobia  (IAGP)
Pleural effusion  (IAGP)
Pneumothorax  (IAGP)
Polyarticular arthritis  (IAGP)
Polyneuropathy  (IAGP)
Portal hypertension  (IAGP)
Precocious puberty  (IAGP)
Proteinuria  (IAGP)
Proximal muscle weakness  (IAGP)
Pruritus  (IAGP)
Psoriasiform dermatitis  (IAGP)
Psychosis  (IAGP)
Ptosis  (IAGP)
Pulmonary arterial hypertension  (IAGP)
Pulmonary artery atresia  (IAGP)
Pulmonary fibrosis  (IAGP)
Pulmonary infiltrates  (IAGP)
Pyuria  (IAGP)
Raynaud phenomenon  (IAGP)
Recurrent infections  (IAGP)
Recurrent pharyngitis  (IAGP)
Renal insufficiency  (IAGP)
Restless legs  (IAGP)
Restlessness  (IAGP)
Restrictive ventilatory defect  (IAGP)
Reticulocytopenia  (IAGP)
Retinopathy  (IAGP)
Sacroiliac arthritis  (IAGP)
Scalp tenderness  (IAGP)
Scarring  (IAGP)
Seizure  (IAGP)
Serositis  (IAGP)
Skin nodule  (IAGP)
Skin plaque  (IAGP)
Skin rash  (IAGP)
Skin ulcer  (IAGP)
Sleep abnormality  (IAGP)
Sleep apnea  (IAGP)
Sleep paralysis  (IAGP)
Slurred speech  (IAGP)
Spasticity  (IAGP)
Splenomegaly  (IAGP)
Sporadic  (IAGP)
Subcutaneous nodule  (IAGP)
Sudden cardiac death  (IAGP)
Syncope  (IAGP)
Systemic lupus erythematosus  (IAGP)
Telangiectasia of the skin  (IAGP)
Thrombocytopenia  (IAGP)
Transient global amnesia  (IAGP)
Tubulointerstitial nephritis  (IAGP)
Type I diabetes mellitus  (IAGP)
Upper airway obstruction  (IAGP)
Urinary hesitancy  (IAGP)
Urinary incontinence  (IAGP)
Urticaria  (IAGP)
Uveitis  (IAGP)
Vasculitis  (IAGP)
Ventricular tachycardia  (IAGP)
Vertigo  (IAGP)
Visual field defect  (IAGP)
Visual hallucination  (IAGP)
Visual impairment  (IAGP)
Visual loss  (IAGP)
Weight loss  (IAGP)
Xerostomia  (IAGP)
References

References - curated
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4. Vitamin D receptor (VDR) gene SNPs influence VDR expression and modulate protection from multiple sclerosis in HLA-DRB1*15-positive individuals. Agliardi C, etal., Brain Behav Immun. 2011 Jun 12.
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9. Relationship between HLA-DR antigen and HLA-DRB1 alleles and prostate cancer in Japanese men. Azuma H, etal., Int Urol Nephrol. 1999;31(3):343-9.
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12. Association of tumor necrosis factor and human leukocyte antigen DRB1 alleles with Graves' ophthalmopathy. Bednarczuk T, etal., Hum Immunol. 2004 Jun;65(6):632-9.
13. To B or not to B: Role of B cells in pathogenesis of arthritis in HLA transgenic mice. Behrens M, etal., J Autoimmun. 2011 Jun 10.
14. Genetic basis of the latex-fruit syndrome: association with HLA class II alleles in a Spanish population. Blanco C, etal., J Allergy Clin Immunol. 2004 Nov;114(5):1070-6.
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16. HLA alleles, IFN-gamma responses to HPV-11 E6, and disease severity in patients with recurrent respiratory papillomatosis. Bonagura VR, etal., Hum Immunol. 2004 Aug;65(8):773-82.
17. Carriage of DRB1*13 is associated with increased posttreatment IgE levels against Schistosoma mansoni antigens and lower long-term reinfection levels. Booth M, etal., J Immunol. 2006 Jun 1;176(11):7112-8. doi: 10.4049/jimmunol.176.11.7112.
18. HLA status in patients with chronic spontaneous urticaria. Bozek A, etal., Int Arch Allergy Immunol. 2010;153(4):419-23. Epub 2010 Jun 18.
19. Increased occurrence of anti-AQP4 seropositivity and unique HLA Class II associations with neuromyelitis optica (NMO), among Muslim Arabs in Israel. Brill L, etal., J Neuroimmunol. 2016 Apr 15;293:65-70. doi: 10.1016/j.jneuroim.2016.02.006. Epub 2016 Feb 15.
20. Analysis of maternal-offspring HLA compatibility, parent-of-origin effects, and noninherited maternal antigen effects for HLA-DRB1 in systemic lupus erythematosus. Bronson PG, etal., Arthritis Rheum. 2010 Jun;62(6):1712-7.
21. Occurrence rates of HLA-DRB1, HLA-DQB1, and HLA-DPB1 alleles in patients suffering from vitiligo. Buc M, etal., Eur J Dermatol. 1998 Jan-Feb;8(1):13-5.
22. HLA class II gene polymorphisms in antiphospholipid syndrome: haplotype analysis in 83 Caucasoid patients. Caliz R, etal., Rheumatology (Oxford). 2001 Jan;40(1):31-6.
23. Peptide immunotherapy in allergic asthma generates IL-10-dependent immunological tolerance associated with linked epitope suppression. Campbell JD, etal., J Exp Med. 2009 Jul 6;206(7):1535-47. Epub 2009 Jun 15.
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25. HLA class II-associated genetic susceptibility in idiopathic progressive sensorineural hearing loss. Cao MY, etal., Ann Otol Rhinol Laryngol. 1996 Aug;105(8):628-33.
26. Tumour necrosis factor microsatellites and HLA-DRB1*, HLA-DQA1*, and HLA-DQB1* alleles in Peruvian patients with rheumatoid arthritis. Castro F, etal., Ann Rheum Dis. 2001 Aug;60(8):791-5.
27. HLA-DRB1*1602 allele is positively associated with HPV cervical infection in Bolivian Andean women. Cervantes J, etal., Hum Immunol. 2003 Sep;64(9):890-5.
28. Comprehensive genotyping in two homogeneous Graves' disease samples reveals major and novel HLA association alleles. Chen PL, etal., PLoS One. 2011 Jan 28;6(1):e16635. doi: 10.1371/journal.pone.0016635.
29. [Correlation study between ischemic stroke and polymorphism of human leucocyte antigen gene]. Chen W, etal., Zhonghua Yi Xue Za Zhi. 2014 Feb 25;94(7):499-502.
30. Microarray studies on effects of Pneumocystis carinii infection on global gene expression in alveolar macrophages. Cheng BH, etal., BMC Microbiol. 2010 Apr 8;10:103.
31. Association of HLA-DRB1 alleles and neuropsychological function in autism. Chien YL, etal., Psychiatr Genet. 2011 Jun 28.
32. Tumour necrosis factor-alpha single nucleotide polymorphisms are not independent of HLA class I in UK Caucasians with adult onset idiopathic inflammatory myopathies. Chinoy H, etal., Rheumatology (Oxford). 2007 Sep;46(9):1411-6. Epub 2007 Jun 22.
33. The HLA DRB1*1501-DQB1*0602-DPB1*0501 haplotype is a risk factor for toluene diisocyanate-induced occupational asthma. Choi JH, etal., Int Arch Allergy Immunol. 2009;150(2):156-63. Epub 2009 May 12.
34. Influence of HLA-DRB1 alleles and HBV genotypes on interferon-alpha therapy for chronic hepatitis B. Chu RH, etal., World J Gastroenterol. 2005 Aug 14;11(30):4753-7. doi: 10.3748/wjg.v11.i30.4753.
35. Distribution of the human leukocyte antigen class II alleles in Brazilian patients with chronic hepatitis C virus infection. Corghi DB, etal., Braz J Med Biol Res. 2008 Oct;41(10):884-9. Epub 2008 Sep 30.
36. Association between high-risk HPV types, HLA DRB1* and DQB1* alleles and cervical cancer in British women. Cuzick J, etal., Br J Cancer. 2000 Apr;82(7):1348-52.
37. HLA-DR and HLA-DQ alleles in patients from the south of Brazil: markers for leprosy susceptibility and resistance. da Silva SA, etal., BMC Infect Dis. 2009 Aug 22;9:134.
38. HLA-DRB1* alleles and symptoms associated with Heerfordt's syndrome in sarcoidosis. Darlington P, etal., Eur Respir J. 2011 Jun 9.
39. Association between human leukocyte antigen polymorphism and human papillomavirus 16-positive vulval intraepithelial neoplasia in British women. Davidson EJ, etal., Cancer Res. 2003 Jan 15;63(2):400-3.
40. Immune responses against human papillomavirus (HPV) type 16 virus-like particles in a cohort study of women with cervical intraepithelial neoplasia. I. Differential T-helper and IgG responses in relation to HPV infection and disease outcome. de Gruijl TD, etal., J Gen Virol. 1999 Feb;80 ( Pt 2):399-408.
41. Human leukocyte antigen class I (A, B) and class II (DRB1) allele and haplotype frequencies in Iranian patients with Buerger's disease. Dehghani Firouzabadi F, etal., Immun Inflamm Dis. 2020 Sep;8(3):434-440. doi: 10.1002/iid3.325. Epub 2020 Jun 21.
42. HLA class II influences humoral autoimmunity in patients with type 2 autoimmune hepatitis. Djilali-Saiah I, etal., J Hepatol. 2006 Dec;45(6):844-50. Epub 2006 Sep 28.
43. HLA-DRB1 and HLA-DQB1 genes in susceptibility and resistance to cicatricial pemphigoid in French Caucasians. Drouet M, etal., Eur J Dermatol. 1998 Jul-Aug;8(5):330-3.
44. HLA class II alleles as markers of tuberculosis susceptibility and resistance. Duarte R, etal., Rev Port Pneumol. 2011 Jan;17(1):15-9.
45. Genes of the class II and class III major histocompatibility complex are associated with typhoid fever in Vietnam. Dunstan SJ, etal., J Infect Dis. 2001 Jan 15;183(2):261-268. doi: 10.1086/317940. Epub 2000 Dec 21.
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49. Heterozygosity or homozygosity for 2 HLA class II haplotypes predict favorable outcomes for renal cell carcinoma treated with cytokine therapy. Ellerhorst JA, etal., J Urol. 2003 Jun;169(6):2084-8.
50. Clinical, immunological, and genetic features of autoimmune primary adrenal insufficiency: observations from a Norwegian registry. Erichsen MM, etal., J Clin Endocrinol Metab. 2009 Dec;94(12):4882-90. Epub 2009 Oct 26.
51. HLA-DRB and HLA-DQ genetic variability in patients with aspirin-exacerbated respiratory disease. Esmaeilzadeh H, etal., Am J Rhinol Allergy. 2015 May-Jun;29(3):e63-9. doi: 10.2500/ajra.2015.29.4154.
52. HLA class II haplotype DRB1*04-DQB1*0301 contributes to risk of familial generalized vitiligo and early disease onset. Fain PR, etal., Pigment Cell Res. 2006 Feb;19(1):51-7.
53. HLA profile in patients with AIDS and tuberculosis. Figueiredo JF, etal., Braz J Infect Dis. 2008 Aug;12(4):278-80. doi: 10.1590/s1413-86702008000400004.
54. The role of the human leukocyte antigen system in retinopathy of prematurity: a pilot study. Flor-de-Lima F, etal., Acta Paediatr. 2013 Aug 29. doi: 10.1111/apa.12410.
55. Coexpression of susceptible and resistant HLA class II transgenes in murine experimental autoimmune thyroiditis: DQ8 molecules downregulate DR3-mediated thyroiditis. Flynn JC, etal., J Autoimmun. 2002 May;18(3):213-20.
56. Distribution of HLA-DRB1 alleles in Argentinean patients with Chagas' disease cardiomyopathy. Garcia Borras S, etal., Immunol Invest. 2009;38(3-4):268-75.
57. HLA-DBR 1 alleles and the susceptibility of Iranian patients with breast cancer. Ghaderi A, etal., Pathol Oncol Res. 2001;7(1):39-41.
58. HLA-DRB and HLA-DQB loci in the genetic susceptibility to develop glaucoma in Mexicans. Gil-Carrasco F, etal., Am J Ophthalmol. 1999 Sep;128(3):297-300.
59. HLA-DRB1*0405 is the predominant allele in Brazilian patients with Vogt-Koyanagi-Harada disease. Goldberg AC, etal., Hum Immunol. 1998 Mar;59(3):183-8.
60. Analysis of HLA haplotypes in autoimmune hepatitis type 1: identifying the major susceptibility locus. Goldberg AC, etal., Hum Immunol. 2001 Feb;62(2):165-9.
61. Clinical course of sarcoidosis in dependence on HLA-DRB1 allele frequencies, inflammatory markers, and the presence of M. tuberculosis DNA fragments. Grosser M, etal., Sarcoidosis Vasc Diffuse Lung Dis. 2005 Mar;22(1):66-74.
62. Human leukocyte antigen (HLA) class I and II alleles in Turkish patients with rheumatic heart disease. Gundogdu F, etal., J Heart Valve Dis. 2007 May;16(3):293-9.
63. Subtypes of HLA-DRB1*03, *08, *11, *12, *13 and *14 in early onset pauciarticular juvenile chronic arthritis (EOPA) with and without iridocyclitis. Haas JP, etal., Clin Exp Rheumatol. 1994 Sep-Oct;12 Suppl 10:S7-14.
64. Relationship of human leukocyte antigen class II genes with the susceptibility to hepatitis B virus infection and the response to interferon in HBV-infected patients. Han YN, etal., World J Gastroenterol. 2005 Sep 28;11(36):5721-4. doi: 10.3748/wjg.v11.i36.5721.
65. Susceptibility alleles and haplotypes of human leukocyte antigen DRB1, DQA1, and DQB1 in autoimmune polyglandular syndrome type III in Japanese population. Hashimoto K, etal., Horm Res. 2005;64(5):253-60. Epub 2005 Oct 27.
66. MICA4/HLA-DRB1*04/TNF1 haplotype is associated with mixed connective tissue disease in Swedish patients. Hassan AB, etal., Hum Immunol. 2003 Feb;64(2):290-6.
67. Prevalent HLA Class II Alleles in Mexico City Appear to Confer Resistance to the Development of Amebic Liver Abscess. Hernández EG, etal., PLoS One. 2015 May 4;10(5):e0126195. doi: 10.1371/journal.pone.0126195. eCollection 2015.
68. Association of HLA-DRB1*0405 with resistance to multibacillary leprosy in Taiwanese. Hsieh NK, etal., Hum Immunol. 2010 Jul;71(7):712-6. Epub 2010 Apr 9.
69. [Possible association between HLA-HRB1 and DQB1 genes frequency and susceptibility or resistance to Helicobacter pylori infection in Kunming Yi ethnic group children]. Huang YK, etal., Zhonghua Er Ke Za Zhi. 2005 Feb;43(2):137-40.
70. HLA-DR alleles determine responsiveness to Borrelia burgdorferi antigens in a mouse model of self-perpetuating arthritis. Iliopoulou BP, etal., Arthritis Rheum. 2009 Dec;60(12):3831-40.
71. Does HLA Class II haplotype play a role in adult acute disseminated encephalomyelitis? Preliminary findings from a Southern Italy hospital-based study. Imbesi D, etal., Arch Ital Biol. 2012 Mar;150(1):1-4. doi: 10.4449/aib.v150i1.1384.
72. The distribution of HLA alleles among children with atopic asthma in Croatia. Ivkovic-Jurekovic I, etal., Coll Antropol. 2011 Dec;35(4):1243-9.
73. Possession of HLA class II DRB1*1303 associates with reduced viral loads in chronic HIV-1 clade C and B infection. Julg B, etal., J Infect Dis. 2011 Mar 15;203(6):803-9. Epub 2011 Jan 21.
74. The association between the HLA system and retinopathy development in patients with type 1 diabetes mellitus. Kastelan S, etal., Coll Antropol. 2013 Apr;37 Suppl 1:65-70.
75. Effect of human leukocyte antigen class II genes on acute-onset and slow-onset type 1 diabetes in the Japanese population. Katahira M, etal., Hum Immunol. 2010 Aug;71(8):789-94. Epub 2010 May 25.
76. Association of human leukocyte antigen class II alleles with severe acute respiratory syndrome in the Vietnamese population. Keicho N, etal., Hum Immunol. 2009 Jul;70(7):527-31. doi: 10.1016/j.humimm.2009.05.006. Epub 2009 May 13.
77. HLA DR and DQ interaction in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in HLA class II transgenic mice. Khare M, etal., J Neuroimmunol. 2005 Dec;169(1-2):1-12. Epub 2005 Sep 27.
78. Immunogenetics and clinical phenotype of sympathetic ophthalmia in British and Irish patients. Kilmartin DJ, etal., Br J Ophthalmol. 2001 Mar;85(3):281-6.
79. Genetic markers for differentiating aspirin-hypersensitivity. Kim SH and Park HS, Yonsei Med J. 2006 Feb 28;47(1):15-21.
80. Mold-sensitivity in children with moderate-severe asthma is associated with HLA-DR and HLA-DQ. Knutsen AP, etal., Allergy. 2010 Nov;65(11):1367-75. doi: 10.1111/j.1398-9995.2010.02382.x. Epub 2010 Jun 16.
81. Association between HLA Class II alleles with HPV mediated Cervical Cancer in Indian women. Kohaar I, etal., Hum Immunol. 2009 Jan 17.
82. HLA-DRB genotypes in Japanese patients with renal cell carcinoma. Kojima Y, etal., Oncology. 2000 Jun;59(1):57-62.
83. Major histocompatibility complex class II (DRB1*, DQA1*, and DQB1*) and DRB1*04 subtypes' associations of Hashimoto's thyroiditis in a Greek population. Kokaraki G, etal., Tissue Antigens. 2009 Mar;73(3):199-205.
84. Efficacy of HLA-DRB1 *03:01 and H2E transgenic mouse strains to correlate pathogenic thyroglobulin epitopes for autoimmune thyroiditis. Kong YC, etal., J Autoimmun. 2011 Jun 17.
85. [HLA-DRB1/DQA1/DQB1 alleles and haplotypes in Czech children with celiac sprue]. Kotalova R, etal., Cas Lek Cesk. 2002 Aug 16;141(16):518-22.
86. HLA associations with multiple sclerosis in Greece. Kouri I, etal., J Neurol Sci. 2011 Jul 7.
87. Genetic alterations of HLA-class II in ovarian cancer. Kubler K, etal., Int J Cancer. 2008 Sep 15;123(6):1350-6.
88. The role of HLA molecules in susceptibility to chronic rheumatic heart disease. Kudat H, etal., Int J Immunogenet. 2006 Feb;33(1):41-4.
89. The 8.1 ancestral MHC haplotype is associated with delayed onset of colonization in cystic fibrosis. Laki J, etal., Int Immunol. 2006 Nov;18(11):1585-90. Epub 2006 Sep 20.
90. Immunogenetics of atopic asthma: association of DRB1*1101 DQA1*0501 DQB1*0301 haplotype with Dermatophagoides spp.-sensitive asthma in a sample of the Venezuelan population. Lara-Marquez ML, etal., Clin Exp Allergy 1999 Jan;29(1):60-71.
91. HLA alleles in Korean patients with Takayasu arteritis. Lee SW, etal., Clin Exp Rheumatol. 2007 Jan-Feb;25(1 Suppl 44):S18-22.
92. HLA-DRB1 and -DQB1 alleles in mestizo patients with Vogt-Koyanagi-Harada's disease in Southern California. Levinson RD, etal., Hum Immunol. 2004 Dec;65(12):1477-82.
93. Strong associations between specific HLA-DQ and HLA-DR alleles and the tubulointerstitial nephritis and uveitis syndrome. Levinson RD, etal., Invest Ophthalmol Vis Sci. 2003 Feb;44(2):653-7.
94. Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions. Li X, etal., J Allergy Clin Immunol. 2010 Feb;125(2):328-335.e11. doi: 10.1016/j.jaci.2009.11.018.
95. A three-way interplay of DR4, autoantibodies and synovitis in biopsy-proven idiopathic inflammatory myositis. Limaye VS, etal., Rheumatol Int. 2010 Dec 2.
96. HLA class I and II alleles are associated with microvascular complications of type 1 diabetes. Lipner EM, etal., Hum Immunol. 2013 May;74(5):538-44. doi: 10.1016/j.humimm.2013.01.013. Epub 2013 Jan 29.
97. [Association of haplotype formed on HLA-DRB1 and HLA-DQA1 alleles with outcomes of hepatitis B virus infection]. Lu LP, etal., Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2006 Aug;23(4):427-30.
98. [Distribution of HLA specificity frequencies in patients with cystic echinococcosis]. Lukmanova GI, etal., Med Parazitol (Mosk). 2011 Oct-Dec;(4):14-6.
99. The association of HLA-DQB1, -DQA1 and -DPB1 alleles with anti- glomerular basement membrane (GBM) disease in Chinese patients. Luo H, etal., BMC Nephrol. 2011 May 13;12:21.
100. Can the prognosis of polymyalgia rheumatica be predicted at disease onset? Results from a 5-year prospective study. Mackie SL, etal., Rheumatology (Oxford). 2010 Apr;49(4):716-22. Epub 2010 Jan 11.
101. Human leukocyte antigen class II and cervical cancer risk: a population-based study. Madeleine MM, etal., J Infect Dis. 2002 Dec 1;186(11):1565-74. Epub 2002 Nov 4.
102. Genetic and diabetic auto-antibody markers in Saudi children with type 1 diabetes. Manan H, etal., Hum Immunol. 2010 Dec;71(12):1238-42. Epub 2010 Sep 19.
103. HLA class II antigens associated with lupus nephritis in Italian SLE patients. Marchini M, etal., Hum Immunol. 2003 Apr;64(4):462-8. doi: 10.1016/s0198-8859(03)00017-x.
104. Human leukocyte antigen type and progression from onset of symptoms to development of asthma. Martyn MB, etal., Allergy Asthma Proc. 2010 Mar;31(2):120-5. Epub 2010 Mar 8.
105. Human papillomavirus type 16 E6 variants and HLA class II alleles among Japanese women with cervical cancer. Matsumoto K, etal., Int J Cancer. 2003 Oct 10;106(6):919-22.
106. HLA class II antigens positively and negatively associated with hepatosplenic schistosomiasis in a Chinese population. McManus DP, etal., Int J Parasitol. 2001 May 15;31(7):674-80. doi: 10.1016/s0020-7519(01)00132-1.
107. Complex HLA-DR and -DQ interactions confer risk of narcolepsy-cataplexy in three ethnic groups. Mignot E, etal., Am J Hum Genet. 2001 Mar;68(3):686-99. Epub 2001 Feb 13.
108. HLA-DRB1*04 and DRB1*14 alleles are associated with susceptibility to pemphigus among Japanese. Miyagawa S, etal., J Invest Dermatol. 1997 Nov;109(5):615-8. doi: 10.1111/1523-1747.ep12337585.
109. Polymorphism located in TCRA locus confers susceptibility to essential hypersomnia with HLA-DRB1*1501-DQB1*0602 haplotype. Miyagawa T, etal., J Hum Genet. 2010 Jan;55(1):63-5. Epub 2009 Nov 20.
110. Human leukocyte antigen serologic and DNA typing of Behcet's disease and its primary association with B51. Mizuki N, etal., Invest Ophthalmol Vis Sci. 1992 Nov;33(12):3332-40.
111. HLA-A*11 and novel associations in Malays and Chinese with systemic lupus erythematosus. Mohd-Yusuf Y, etal., Immunol Lett. 2011 Sep 30;139(1-2):68-72. Epub 2011 May 30.
112. HLA-DRB1, -DQA1, and -DQB1 genotypes in patients with nasal polyposis. Molnar-Gabor E, etal., Laryngoscope. 2000 Mar;110(3 Pt 1):422-5.
113. Association of FCGR2A and FCGR2A-FCGR3A haplotypes with susceptibility to giant cell arteritis. Morgan AW, etal., Arthritis Res Ther. 2006;8(4):R109.
114. Clinical and genetic characteristics of patients with autoimmune thyroid disease with anti-islet autoimmunity. Moriguchi M, etal., Metabolism. 2011 Jun;60(6):761-6. Epub 2010 Sep 9.
115. HLA-DRB1 and HLA-DQB1 genes on susceptibility to and protection from allergic bronchopulmonary aspergillosis in patients with cystic fibrosis. Muro M, etal., Microbiol Immunol. 2013 Mar;57(3):193-7. doi: 10.1111/1348-0421.12020.
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