H2-Eb1 (histocompatibility 2, class II antigen E beta) - Rat Genome Database

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Gene: H2-Eb1 (histocompatibility 2, class II antigen E beta) Mus musculus
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Symbol: H2-Eb1
Name: histocompatibility 2, class II antigen E beta
RGD ID: 1558147
MGI Page MGI
Description: Predicted to enable several functions, including MHC class II receptor activity; peptide antigen binding activity; and signaling receptor binding activity. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II. Predicted to be located in external side of plasma membrane and immunological synapse. Predicted to be part of MHC class II protein complex. Predicted to be active in late endosome membrane and lysosomal membrane. Is expressed in lung. Human ortholog(s) of this gene implicated in several diseases, including asthma (multiple); autoimmune disease (multiple); bacterial infectious disease (multiple); eye disease (multiple); and sarcoidosis (multiple). Orthologous to several human genes including HLA-DRB5 (major histocompatibility complex, class II, DR beta 5).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cell surface glycoprotein; Eb; H-2 class II histocompatibility antigen, I-E beta chain; H-2Eb; H2-Eb_p; H2Eb; histocompatibility 2, class II antigen E beta, promoter 1; I; I-E beta MHC class II; Ia; Ia-4; Ia4; major histocompatibility complex H-2E beta chain; MGC163794; MGC163796; MHC class II antigen beta chain; MHC class II IE-b; MHC H2-IE-beta cell surface glycoprotein
RGD Orthologs
Human
Rat
Dog
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,524,841 - 34,535,648 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1734,524,841 - 34,535,648 (+)EnsemblGRCm39 Ensembl
GRCm381734,305,867 - 34,316,674 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,305,867 - 34,316,674 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,442,812 - 34,453,619 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361733,913,637 - 33,923,895 (+)NCBIMGSCv36mm8
Celera1737,067,715 - 37,078,914 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
abdominal aortic aneurysm  (ISO)
Actinic Prurigo  (ISO)
acute disseminated encephalomyelitis  (ISO)
Addison's disease  (ISO)
allergic asthma  (ISO)
allergic bronchopulmonary aspergillosis  (ISO)
allergic disease  (ISO)
Alport syndrome  (ISO)
alveolar echinococcosis  (ISO)
Alzheimer's disease  (ISO)
Amebic Liver Abscess  (ISO)
angioedema  (ISO)
ankylosing spondylitis  (ISO)
anti-basement membrane glomerulonephritis  (ISO)
antiphospholipid syndrome  (ISO)
aspirin-induced respiratory disease  (ISO)
asthma  (ISO)
atrophic gastritis  (ISO)
autistic disorder  (ISO)
autoimmune disease  (ISO)
autoimmune hepatitis  (ISO)
autoimmune polyendocrine syndrome  (ISO)
autoimmune polyendocrine syndrome type 2  (ISO)
autoimmune thrombocytopenic purpura  (ISO)
autoimmune thyroiditis  (ISO)
bacterial infectious disease  (ISO)
Behcet's disease  (ISO)
berylliosis  (ISO)
breast cancer  (ISO)
breast carcinoma  (ISO)
celiac disease  (ISO)
cerebral infarction  (ISO)
cervix uteri carcinoma in situ  (ISO)
Chagas Cardiomyopathy  (ISO)
Chagas disease  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
choreatic disease  (ISO)
Chronic Hepatitis B  (ISO)
Chronic Hepatitis C  (ISO)
cicatricial pemphigoid  (ISO)
COVID-19  (ISO)
Crohn's disease  (ISO)
cystic echinococcosis  (ISO)
diabetic angiopathy  (ISO)
diabetic retinopathy  (ISO)
drug allergy  (ISO)
End Stage Liver Disease  (ISO)
endometriosis  (ISO)
eosinophilia-myalgia syndrome  (ISO)
Experimental Arthritis  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Liver Cirrhosis  (ISO)
Germ Cell and Embryonal Neoplasms  (ISO)
glaucoma  (ISO)
Graves' disease  (ISO)
Hantavirus hemorrhagic fever with renal syndrome  (ISO)
Hashimoto Disease  (ISO)
Helicobacter Infections  (ISO)
hepatitis C  (ISO)
HIV Seropositivity  (ISO)
human immunodeficiency virus infectious disease  (ISO)
Human Influenza  (ISO)
hypothyroidism  (ISO)
Idiopathic Hypersomnolence  (ISO)
idiopathic pulmonary fibrosis  (ISO)
infectious mononucleosis  (ISO)
Juvenile Pauciarticular Chronic Arthritis  (ISO)
juvenile rheumatoid arthritis  (ISO)
latex allergy  (ISO)
leprosy  (ISO)
liver cirrhosis  (ISO)
lupus nephritis  (ISO)
membranous glomerulonephritis  (ISO)
Meniere's disease  (ISO)
mixed connective tissue disease  (ISO)
Multibacillary Leprosy  (ISO)
multidrug-resistant tuberculosis  (ISO)
multiple sclerosis  (ISO)
myasthenia gravis  (ISO)
Mycobacterium Infections  (ISO)
myositis  (ISO)
narcolepsy  (ISO)
Nasal Polyps  (ISO)
nephrotic syndrome  (ISO)
neuromyelitis optica  (ISO)
non-Hodgkin lymphoma  (ISO)
optic neuritis  (ISO)
Oropharyngeal Neoplasms  (ISO)
Ovarian Neoplasms  (ISO)
pancreatitis  (ISO)
papillomavirus infectious disease  (ISO)
paracoccidioidomycosis  (ISO)
Parkinson's disease  (ISO)
pemphigus  (ISO)
peptic ulcer disease  (ISO)
PERITONEAL GLIOMATOSIS  (ISO)
Pneumocystis Infections  (ISO)
polyneuropathy  (ISO)
primary progressive multiple sclerosis  (ISO)
prostate cancer  (ISO)
proteasome-associated autoinflammatory syndrome 1  (ISO)
proteinuria  (ISO)
Pulmonary Atresia  (ISO)
pulmonary sarcoidosis  (ISO)
pulmonary tuberculosis  (ISO)
pure red-cell aplasia  (ISO)
Recurrent Respiratory Papillomatosis  (ISO)
renal cell carcinoma  (ISO)
retinopathy of prematurity  (ISO)
rheumatic fever  (ISO)
rheumatic heart disease  (ISO)
rheumatoid arthritis  (ISO)
sarcoidosis  (ISO)
schistosomiasis  (ISO)
schizophrenia  (ISO)
sensorineural hearing loss  (ISO)
severe acute respiratory syndrome  (ISO)
Sjogren's syndrome  (ISO)
Stroke  (ISO)
Sudden Hearing Loss  (ISO)
sympathetic ophthalmia  (ISO)
systemic lupus erythematosus  (ISO)
Takayasu's arteritis  (ISO)
temporal arteritis  (ISO)
thromboangiitis obliterans  (ISO)
toxic shock syndrome  (ISO)
Trichiasis  (ISO)
tuberculosis  (ISO)
Tubulointerstitial Nephritis and Uveitis  (ISO)
type 1 diabetes mellitus  (ISO)
typhoid fever  (ISO)
ulcerative colitis  (ISO)
urticaria  (ISO)
Uterine Cervical Neoplasms  (ISO)
uveitis  (ISO)
uveoparotid fever  (ISO)
visceral leishmaniasis  (ISO)
vitiligo  (ISO)
Vogt-Koyanagi-Harada disease  (ISO)
vulva cancer  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2-hydroxypropanoic acid  (ISO)
3,7-dihydropurine-6-thione  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acetylsalicylic acid  (ISO)
acrylamide  (ISO)
all-trans-retinoic acid  (EXP)
alpha-Zearalanol  (ISO)
amitriptyline  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
auranofin  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
Benzo[k]fluoranthene  (EXP)
beryllium sulfate  (ISO)
bexarotene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
C60 fullerene  (EXP)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (EXP,ISO)
cefepime  (ISO)
celecoxib  (ISO)
choline  (EXP)
ciprofloxacin  (ISO)
clindamycin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
D-penicillamine  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
dichloromethane  (ISO)
diclofenac  (ISO)
diethylstilbestrol  (EXP)
diltiazem  (ISO)
diquat  (EXP)
diuron  (ISO)
doxorubicin  (EXP)
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor  (ISO)
epoxiconazole  (EXP)
ethylbenzene  (ISO)
ethylparaben  (ISO)
fenofibrate  (EXP)
ferric oxide  (EXP)
flutamide  (ISO)
fulvestrant  (ISO)
gefitinib  (ISO)
genistein  (EXP)
gentamycin  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
hexachlorobenzene  (ISO)
hydrochlorothiazide  (ISO)
irinotecan  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
isoprenaline  (EXP)
lead(0)  (ISO)
lumiracoxib  (ISO)
mercaptopurine  (ISO)
metronidazole  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
monosodium L-glutamate  (ISO)
N-(6-acetamidohexyl)acetamide  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
nickel atom  (EXP)
nickel dichloride  (ISO)
nicotine  (ISO)
nitric oxide  (ISO)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
palladium  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
PCB138  (ISO)
perfluorobutyric acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
pirinixic acid  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
purine-6-thiol  (ISO)
quercetin  (EXP)
rac-lactic acid  (ISO)
S-adenosyl-L-methioninate  (EXP)
S-adenosyl-L-methionine  (EXP)
sodium arsenite  (EXP)
succimer  (EXP)
tamoxifen  (EXP,ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
tremolite asbestos  (EXP)
Tributyltin oxide  (ISO)
trichloroethene  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
triptonide  (EXP)
valproic acid  (ISO)
vancomycin  (EXP)
vinclozolin  (ISO)
vorinostat  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adaptive immune response  (IEA)
antigen processing and presentation  (IEA)
antigen processing and presentation of endogenous peptide antigen via MHC class II  (ISO)
antigen processing and presentation of exogenous peptide antigen via MHC class II  (IBA,IDA)
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II  (IEA)
humoral immune response  (ISO)
immune response  (IEA)
immune system process  (IEA)
inflammatory response to antigenic stimulus  (ISO)
macrophage differentiation  (ISO)
myeloid dendritic cell antigen processing and presentation  (ISO)
negative regulation of inflammatory response to antigenic stimulus  (ISO)
negative regulation of T cell proliferation  (ISO)
negative regulation of type II interferon production  (ISO)
peptide antigen assembly with MHC class II protein complex  (IBA)
positive regulation of canonical NF-kappaB signal transduction  (ISO)
positive regulation of CD4-positive, alpha-beta T cell activation  (ISO)
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation  (ISO)
positive regulation of DNA-templated transcription  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of immune response  (IBA)
positive regulation of insulin secretion involved in cellular response to glucose stimulus  (ISO)
positive regulation of kinase activity  (ISO)
positive regulation of MAPK cascade  (ISO)
positive regulation of memory T cell differentiation  (ISO)
positive regulation of monocyte differentiation  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of T cell activation  (IBA)
positive regulation of T cell mediated cytotoxicity  (ISO)
positive regulation of T cell mediated immune response to tumor cell  (ISO)
positive regulation of viral entry into host cell  (ISO)
protein tetramerization  (ISO)
regulation of interleukin-10 production  (ISO)
regulation of interleukin-4 production  (ISO)
regulation of T-helper cell differentiation  (ISO)
response to dexamethasone  (ISO)
response to type II interferon  (IDA)
signal transduction  (ISO)
T cell receptor signaling pathway  (ISO)
T-helper 1 type immune response  (ISO)

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Human leukocyte antigen (HLA)-B, DRB1, and DQB1 allotypes associated with disease and protection of trachoma endemic villagers. Abbas M, etal., Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1734-8. doi: 10.1167/iovs.08-2053. Epub 2008 Sep 29.
2. Neuroprotective effects of recombinant T-cell receptor ligand in autoimmune optic neuritis in HLA-DR2 mice. Adamus G, etal., Invest Ophthalmol Vis Sci. 2012 Jan 25;53(1):406-12. doi: 10.1167/iovs.11-8419.
3. Selected class I and class II HLA alleles and haplotypes and risk of high-grade cervical intraepithelial neoplasia. Ades S, etal., Int J Cancer. 2008 Jun 15;122(12):2820-6.
4. Vitamin D receptor (VDR) gene SNPs influence VDR expression and modulate protection from multiple sclerosis in HLA-DRB1*15-positive individuals. Agliardi C, etal., Brain Behav Immun. 2011 Jun 12.
5. Strong association of HLA class II sequences in Mexicans with Vogt-Koyanagi-Harada's disease. Alaez C, etal., Hum Immunol. 1999 Sep;60(9):875-82.
6. The rheumatoid arthritis-associated allele HLA-DR10 (DRB1*1001) shares part of its repertoire with HLA-DR1 (DRB1*0101) and HLA-DR4 (DRB*0401). Alvarez I, etal., Arthritis Rheum. 2008 Jun;58(6):1630-9.
7. Acute disseminated encephalomyelitis: clinical features, HLA DRB1*1501, HLA DRB1*1503, HLA DQA1*0102, HLA DQB1*0602, and HLA DPA1*0301 allelic association study. Alves-Leon SV, etal., Arq Neuropsiquiatr. 2009 Sep;67(3A):643-51.
8. Human leukocyte antigen-DQB1 and -DRB1 associations in patients with idiopathic sudden sensorineural hearing loss from a defined population of Northwest Spain. Amor-Dorado JC, etal., Acta Otolaryngol. 2005 Dec;125(12):1277-82.
9. Relationship between HLA-DR antigen and HLA-DRB1 alleles and prostate cancer in Japanese men. Azuma H, etal., Int Urol Nephrol. 1999;31(3):343-9.
10. HLA class II polymorphism: protective or risk factors to breast cancer in Tunisia? Baccar Harrath A, etal., Pathol Oncol Res. 2006;12(2):79-81. Epub 2006 Jun 24.
11. Alport syndrome: HLA association and kidney graft outcome. Barocci S, etal., Eur J Immunogenet. 2004 Jun;31(3):115-9.
12. Association of tumor necrosis factor and human leukocyte antigen DRB1 alleles with Graves' ophthalmopathy. Bednarczuk T, etal., Hum Immunol. 2004 Jun;65(6):632-9.
13. To B or not to B: Role of B cells in pathogenesis of arthritis in HLA transgenic mice. Behrens M, etal., J Autoimmun. 2011 Jun 10.
14. Genetic basis of the latex-fruit syndrome: association with HLA class II alleles in a Spanish population. Blanco C, etal., J Allergy Clin Immunol. 2004 Nov;114(5):1070-6.
15. [HLA-DRB1 typing in Caucasians patients with neuromyelitis optica.] Blanco Y, etal., Rev Neurol. 2011 Aug 1;53(3):146-152.
16. HLA alleles, IFN-gamma responses to HPV-11 E6, and disease severity in patients with recurrent respiratory papillomatosis. Bonagura VR, etal., Hum Immunol. 2004 Aug;65(8):773-82.
17. Carriage of DRB1*13 is associated with increased posttreatment IgE levels against Schistosoma mansoni antigens and lower long-term reinfection levels. Booth M, etal., J Immunol. 2006 Jun 1;176(11):7112-8. doi: 10.4049/jimmunol.176.11.7112.
18. HLA status in patients with chronic spontaneous urticaria. Bozek A, etal., Int Arch Allergy Immunol. 2010;153(4):419-23. Epub 2010 Jun 18.
19. Increased occurrence of anti-AQP4 seropositivity and unique HLA Class II associations with neuromyelitis optica (NMO), among Muslim Arabs in Israel. Brill L, etal., J Neuroimmunol. 2016 Apr 15;293:65-70. doi: 10.1016/j.jneuroim.2016.02.006. Epub 2016 Feb 15.
20. Analysis of maternal-offspring HLA compatibility, parent-of-origin effects, and noninherited maternal antigen effects for HLA-DRB1 in systemic lupus erythematosus. Bronson PG, etal., Arthritis Rheum. 2010 Jun;62(6):1712-7.
21. Occurrence rates of HLA-DRB1, HLA-DQB1, and HLA-DPB1 alleles in patients suffering from vitiligo. Buc M, etal., Eur J Dermatol. 1998 Jan-Feb;8(1):13-5.
22. HLA class II gene polymorphisms in antiphospholipid syndrome: haplotype analysis in 83 Caucasoid patients. Caliz R, etal., Rheumatology (Oxford). 2001 Jan;40(1):31-6.
23. Peptide immunotherapy in allergic asthma generates IL-10-dependent immunological tolerance associated with linked epitope suppression. Campbell JD, etal., J Exp Med. 2009 Jul 6;206(7):1535-47. Epub 2009 Jun 15.
24. HLA class II-associated genetic susceptibility in idiopathic progressive sensorineural hearing loss. Cao MY, etal., Ann Otol Rhinol Laryngol. 1996 Aug;105(8):628-33.
25. Tumour necrosis factor microsatellites and HLA-DRB1*, HLA-DQA1*, and HLA-DQB1* alleles in Peruvian patients with rheumatoid arthritis. Castro F, etal., Ann Rheum Dis. 2001 Aug;60(8):791-5.
26. HLA-DRB1*1602 allele is positively associated with HPV cervical infection in Bolivian Andean women. Cervantes J, etal., Hum Immunol. 2003 Sep;64(9):890-5.
27. Comprehensive genotyping in two homogeneous Graves' disease samples reveals major and novel HLA association alleles. Chen PL, etal., PLoS One. 2011 Jan 28;6(1):e16635. doi: 10.1371/journal.pone.0016635.
28. Microarray studies on effects of Pneumocystis carinii infection on global gene expression in alveolar macrophages. Cheng BH, etal., BMC Microbiol. 2010 Apr 8;10:103.
29. Association of HLA-DRB1 alleles and neuropsychological function in autism. Chien YL, etal., Psychiatr Genet. 2011 Jun 28.
30. Tumour necrosis factor-alpha single nucleotide polymorphisms are not independent of HLA class I in UK Caucasians with adult onset idiopathic inflammatory myopathies. Chinoy H, etal., Rheumatology (Oxford). 2007 Sep;46(9):1411-6. Epub 2007 Jun 22.
31. The HLA DRB1*1501-DQB1*0602-DPB1*0501 haplotype is a risk factor for toluene diisocyanate-induced occupational asthma. Choi JH, etal., Int Arch Allergy Immunol. 2009;150(2):156-63. Epub 2009 May 12.
32. Distribution of the human leukocyte antigen class II alleles in Brazilian patients with chronic hepatitis C virus infection. Corghi DB, etal., Braz J Med Biol Res. 2008 Oct;41(10):884-9. Epub 2008 Sep 30.
33. Association between high-risk HPV types, HLA DRB1* and DQB1* alleles and cervical cancer in British women. Cuzick J, etal., Br J Cancer. 2000 Apr;82(7):1348-52.
34. HLA-DR and HLA-DQ alleles in patients from the south of Brazil: markers for leprosy susceptibility and resistance. da Silva SA, etal., BMC Infect Dis. 2009 Aug 22;9:134.
35. HLA-DRB1* alleles and symptoms associated with Heerfordt's syndrome in sarcoidosis. Darlington P, etal., Eur Respir J. 2011 Jun 9.
36. Association between human leukocyte antigen polymorphism and human papillomavirus 16-positive vulval intraepithelial neoplasia in British women. Davidson EJ, etal., Cancer Res. 2003 Jan 15;63(2):400-3.
37. Immune responses against human papillomavirus (HPV) type 16 virus-like particles in a cohort study of women with cervical intraepithelial neoplasia. I. Differential T-helper and IgG responses in relation to HPV infection and disease outcome. de Gruijl TD, etal., J Gen Virol. 1999 Feb;80 ( Pt 2):399-408.
38. HLA class II influences humoral autoimmunity in patients with type 2 autoimmune hepatitis. Djilali-Saiah I, etal., J Hepatol. 2006 Dec;45(6):844-50. Epub 2006 Sep 28.
39. HLA-DRB1 and HLA-DQB1 genes in susceptibility and resistance to cicatricial pemphigoid in French Caucasians. Drouet M, etal., Eur J Dermatol. 1998 Jul-Aug;8(5):330-3.
40. HLA class II alleles as markers of tuberculosis susceptibility and resistance. Duarte R, etal., Rev Port Pneumol. 2011 Jan;17(1):15-9.
41. Genes of the class II and class III major histocompatibility complex are associated with typhoid fever in Vietnam. Dunstan SJ, etal., J Infect Dis. 2001 Jan 15;183(2):261-268. doi: 10.1086/317940. Epub 2000 Dec 21.
42. Variation at HLA-DRB1 is associated with resistance to enteric fever. Dunstan SJ, etal., Nat Genet. 2014 Dec;46(12):1333-6. doi: 10.1038/ng.3143. Epub 2014 Nov 10.
43. No association between bronchial asthma and HLA-DRB1, -DQB1 alleles in the Slovak population. Dzurilla M, etal., Bratisl Lek Listy. 2013;114(2):93-5.
44. HLA and alveolar echinococcosis. Eiermann TH, etal., Tissue Antigens. 1998 Aug;52(2):124-9. doi: 10.1111/j.1399-0039.1998.tb02275.x.
45. Heterozygosity or homozygosity for 2 HLA class II haplotypes predict favorable outcomes for renal cell carcinoma treated with cytokine therapy. Ellerhorst JA, etal., J Urol. 2003 Jun;169(6):2084-8.
46. Clinical, immunological, and genetic features of autoimmune primary adrenal insufficiency: observations from a Norwegian registry. Erichsen MM, etal., J Clin Endocrinol Metab. 2009 Dec;94(12):4882-90. Epub 2009 Oct 26.
47. HLA-DRB and HLA-DQ genetic variability in patients with aspirin-exacerbated respiratory disease. Esmaeilzadeh H, etal., Am J Rhinol Allergy. 2015 May-Jun;29(3):e63-9. doi: 10.2500/ajra.2015.29.4154.
48. HLA class II haplotype DRB1*04-DQB1*0301 contributes to risk of familial generalized vitiligo and early disease onset. Fain PR, etal., Pigment Cell Res. 2006 Feb;19(1):51-7.
49. HLA profile in patients with AIDS and tuberculosis. Figueiredo JF, etal., Braz J Infect Dis. 2008 Aug;12(4):278-80. doi: 10.1590/s1413-86702008000400004.
50. The role of the human leukocyte antigen system in retinopathy of prematurity: a pilot study. Flor-de-Lima F, etal., Acta Paediatr. 2013 Aug 29. doi: 10.1111/apa.12410.
51. Coexpression of susceptible and resistant HLA class II transgenes in murine experimental autoimmune thyroiditis: DQ8 molecules downregulate DR3-mediated thyroiditis. Flynn JC, etal., J Autoimmun. 2002 May;18(3):213-20.
52. Distribution of HLA-DRB1 alleles in Argentinean patients with Chagas' disease cardiomyopathy. Garcia Borras S, etal., Immunol Invest. 2009;38(3-4):268-75.
53. HLA-DBR 1 alleles and the susceptibility of Iranian patients with breast cancer. Ghaderi A, etal., Pathol Oncol Res. 2001;7(1):39-41.
54. HLA-DRB and HLA-DQB loci in the genetic susceptibility to develop glaucoma in Mexicans. Gil-Carrasco F, etal., Am J Ophthalmol. 1999 Sep;128(3):297-300.
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57. Human leukocyte antigen (HLA) class I and II alleles in Turkish patients with rheumatic heart disease. Gundogdu F, etal., J Heart Valve Dis. 2007 May;16(3):293-9.
58. Subtypes of HLA-DRB1*03, *08, *11, *12, *13 and *14 in early onset pauciarticular juvenile chronic arthritis (EOPA) with and without iridocyclitis. Haas JP, etal., Clin Exp Rheumatol. 1994 Sep-Oct;12 Suppl 10:S7-14.
59. Relationship of human leukocyte antigen class II genes with the susceptibility to hepatitis B virus infection and the response to interferon in HBV-infected patients. Han YN, etal., World J Gastroenterol. 2005 Sep 28;11(36):5721-4. doi: 10.3748/wjg.v11.i36.5721.
60. Susceptibility alleles and haplotypes of human leukocyte antigen DRB1, DQA1, and DQB1 in autoimmune polyglandular syndrome type III in Japanese population. Hashimoto K, etal., Horm Res. 2005;64(5):253-60. Epub 2005 Oct 27.
61. MICA4/HLA-DRB1*04/TNF1 haplotype is associated with mixed connective tissue disease in Swedish patients. Hassan AB, etal., Hum Immunol. 2003 Feb;64(2):290-6.
62. Prevalent HLA Class II Alleles in Mexico City Appear to Confer Resistance to the Development of Amebic Liver Abscess. Hernández EG, etal., PLoS One. 2015 May 4;10(5):e0126195. doi: 10.1371/journal.pone.0126195. eCollection 2015.
63. Association of HLA-DRB1*0405 with resistance to multibacillary leprosy in Taiwanese. Hsieh NK, etal., Hum Immunol. 2010 Jul;71(7):712-6. Epub 2010 Apr 9.
64. [Possible association between HLA-HRB1 and DQB1 genes frequency and susceptibility or resistance to Helicobacter pylori infection in Kunming Yi ethnic group children]. Huang YK, etal., Zhonghua Er Ke Za Zhi. 2005 Feb;43(2):137-40.
65. HLA-DR alleles determine responsiveness to Borrelia burgdorferi antigens in a mouse model of self-perpetuating arthritis. Iliopoulou BP, etal., Arthritis Rheum. 2009 Dec;60(12):3831-40.
66. Does HLA Class II haplotype play a role in adult acute disseminated encephalomyelitis? Preliminary findings from a Southern Italy hospital-based study. Imbesi D, etal., Arch Ital Biol. 2012 Mar;150(1):1-4. doi: 10.4449/aib.v150i1.1384.
67. The distribution of HLA alleles among children with atopic asthma in Croatia. Ivkovic-Jurekovic I, etal., Coll Antropol. 2011 Dec;35(4):1243-9.
68. Possession of HLA class II DRB1*1303 associates with reduced viral loads in chronic HIV-1 clade C and B infection. Julg B, etal., J Infect Dis. 2011 Mar 15;203(6):803-9. Epub 2011 Jan 21.
69. The association between the HLA system and retinopathy development in patients with type 1 diabetes mellitus. Kastelan S, etal., Coll Antropol. 2013 Apr;37 Suppl 1:65-70.
70. Effect of human leukocyte antigen class II genes on acute-onset and slow-onset type 1 diabetes in the Japanese population. Katahira M, etal., Hum Immunol. 2010 Aug;71(8):789-94. Epub 2010 May 25.
71. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
72. HLA DR and DQ interaction in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in HLA class II transgenic mice. Khare M, etal., J Neuroimmunol. 2005 Dec;169(1-2):1-12. Epub 2005 Sep 27.
73. Immunogenetics and clinical phenotype of sympathetic ophthalmia in British and Irish patients. Kilmartin DJ, etal., Br J Ophthalmol. 2001 Mar;85(3):281-6.
74. Mold-sensitivity in children with moderate-severe asthma is associated with HLA-DR and HLA-DQ. Knutsen AP, etal., Allergy. 2010 Nov;65(11):1367-75. doi: 10.1111/j.1398-9995.2010.02382.x. Epub 2010 Jun 16.
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76. HLA-DRB genotypes in Japanese patients with renal cell carcinoma. Kojima Y, etal., Oncology. 2000 Jun;59(1):57-62.
77. Major histocompatibility complex class II (DRB1*, DQA1*, and DQB1*) and DRB1*04 subtypes' associations of Hashimoto's thyroiditis in a Greek population. Kokaraki G, etal., Tissue Antigens. 2009 Mar;73(3):199-205.
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80. HLA associations with multiple sclerosis in Greece. Kouri I, etal., J Neurol Sci. 2011 Jul 7.
81. Genetic alterations of HLA-class II in ovarian cancer. Kubler K, etal., Int J Cancer. 2008 Sep 15;123(6):1350-6.
82. The role of HLA molecules in susceptibility to chronic rheumatic heart disease. Kudat H, etal., Int J Immunogenet. 2006 Feb;33(1):41-4.
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85. HLA-DRB1 and -DQB1 alleles in mestizo patients with Vogt-Koyanagi-Harada's disease in Southern California. Levinson RD, etal., Hum Immunol. 2004 Dec;65(12):1477-82.
86. Strong associations between specific HLA-DQ and HLA-DR alleles and the tubulointerstitial nephritis and uveitis syndrome. Levinson RD, etal., Invest Ophthalmol Vis Sci. 2003 Feb;44(2):653-7.
87. Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions. Li X, etal., J Allergy Clin Immunol. 2010 Feb;125(2):328-335.e11. doi: 10.1016/j.jaci.2009.11.018.
88. A three-way interplay of DR4, autoantibodies and synovitis in biopsy-proven idiopathic inflammatory myositis. Limaye VS, etal., Rheumatol Int. 2010 Dec 2.
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92. The association of HLA-DQB1, -DQA1 and -DPB1 alleles with anti- glomerular basement membrane (GBM) disease in Chinese patients. Luo H, etal., BMC Nephrol. 2011 May 13;12:21.
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125. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
126. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
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132. Mouse MP Annotation Import Pipeline RGD automated import pipeline
133. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
134. Infection of HLA-DR1 transgenic mice with a human isolate of influenza a virus (H1N1) primes a diverse CD4 T-cell repertoire that includes CD4 T cells with heterosubtypic cross-reactivity to avian (H5N1) influenza virus. Richards KA, etal., J Virol. 2009 Jul;83(13):6566-77. Epub 2009 Apr 22.
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137. Generic human leukocyte antigen class II (DRB1 and DQB1) alleles in patients with paracoccidioidomycosis. Sadahiro A, etal., Med Mycol. 2007 Feb;45(1):35-40.
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141. Regression of low-grade cervical intraepithelial neoplasia in patients with HLA-DRB1*13 genotype. Sastre-Garau X, etal., Obstet Gynecol. 2004 Oct;104(4):751-5.
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146. A variant of childhood-onset myasthenia gravis: HLA typing and clinical characteristics in Japan. Shinomiya N, etal., Clin Immunol. 2004 Feb;110(2):154-8.
147. Multiple Loci in the HLA Complex Are Associated with Addison's Disease. Skinningsrud B, etal., J Clin Endocrinol Metab. 2011 Aug 3.
148. Chronic hepatitis C infection and sicca syndrome: a clear association with HLA DQB1*02. Smyth CM, etal., Eur J Gastroenterol Hepatol. 2007 Jun;19(6):493-8. doi: 10.1097/MEG.0b013e328010687d.
149. HLA class II DR and DQ genotypes and haplotypes associated with rheumatic fever among a clinically homogeneous patient population of Latvian children. Stanevicha V, etal., Arthritis Res Ther. 2007;9(3):R58.
150. Endometriosis and autoimmune disease: association of susceptibility to moderate/severe endometriosis with CCL21 and HLA-DRB1. Sundqvist J, etal., Fertil Steril. 2011 Jan;95(1):437-40. Epub 2010 Aug 24.
151. Increased frequency of HLA-DRB1*15 in patients with multifocal motor neuropathy. Sutedja NA, etal., Neurology. 2010 Mar 9;74(10):828-32.
152. Genetic characterization and susceptibility for sarcoidosis in Japanese patients: risk factors of BTNL2 gene polymorphisms and HLA class II alleles. Suzuki H, etal., Invest Ophthalmol Vis Sci. 2012 Oct 11;53(11):7109-15. doi: 10.1167/iovs.12-10491.
153. HLA class II DPB1, DQA1, DQB1, and DRB1 genotypic associations with occupational allergic cough to Bunashimeji mushroom. Suzuki K, etal., Tissue Antigens. 2005 May;65(5):459-66.
154. Human leukocyte antigens and HIV type 1 viral load in early and chronic infection: predominance of evolving relationships. Tang J, etal., PLoS One. 2010 Mar 10;5(3):e9629.
155. Sequence feature variant type (sfvt) analysis of the hla genetic association in juvenile idiopathic arthritis. Thomson G, etal., Pac Symp Biocomput. 2010:359-70.
156. A shared HLA-DRB1 epitope in the DR beta first domain is associated with Vogt-Koyanagi-Harada syndrome in Indian patients. Tiercy JM, etal., Mol Vis. 2010 Mar 5;16:353-8.
157. Low frequency of HLA-DRB1*11 in hepatitis C virus induced end stage liver disease. Tillmann HL, etal., Gut. 2001 May;48(5):714-8. doi: 10.1136/gut.48.5.714.
158. Strain-based HLA association analysis identified HLA-DRB1*09:01 associated with modern strain tuberculosis. Toyo-Oka L, etal., HLA. 2017 Sep;90(3):149-156. doi: 10.1111/tan.13070. Epub 2017 Jun 14.
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160. Does the DRB1*1501 allele confer more severe and faster progression in primary progressive multiple sclerosis patients? HLA in primary progressive multiple sclerosis. Vasconcelos CC, etal., J Neuroimmunol. 2009 Sep 29;214(1-2):101-3. Epub 2009 Jul 17.
161. Differences in the genetic background of latent autoimmune diabetes in adults (LADA) and type 1 diabetes mellitus. Vatay A, etal., Immunol Lett. 2002 Nov 1;84(2):109-115.
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Additional References at PubMed
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Genomics

Comparative Map Data
H2-Eb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,524,841 - 34,535,648 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1734,524,841 - 34,535,648 (+)EnsemblGRCm39 Ensembl
GRCm381734,305,867 - 34,316,674 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,305,867 - 34,316,674 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,442,812 - 34,453,619 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361733,913,637 - 33,923,895 (+)NCBIMGSCv36mm8
Celera1737,067,715 - 37,078,914 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
HLA-DRB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38632,578,775 - 32,589,848 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl632,577,902 - 32,589,848 (-)EnsemblGRCh38hg38GRCh38
GRCh37632,546,552 - 32,557,625 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36632,654,527 - 32,665,559 (-)NCBINCBI36Build 36hg18NCBI36
Build 34632,654,526 - 32,665,559NCBI
Cytogenetic Map6p21.32NCBI
CHM1_1632,549,025 - 32,560,089 (-)NCBICHM1_1
T2T-CHM13v2.0632,408,987 - 32,422,414 (-)NCBIT2T-CHM13v2.0
RT1-Db1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8204,550,594 - 4,560,182 (-)NCBIGRCr8
mRatBN7.2204,548,664 - 4,558,237 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl204,548,666 - 4,558,258 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0204,087,621 - 4,097,190 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,087,618 - 4,097,190 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,167,759 - 6,177,328 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,671,489 - 4,681,058 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera206,150,824 - 6,160,393 (-)NCBICelera
Cytogenetic Map20p12NCBI
DLA-DRB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1122,151,409 - 2,164,564 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha122,300,636 - 2,313,266 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0122,427,792 - 2,440,407 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1122,150,930 - 2,163,511 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0122,232,117 - 2,244,754 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0122,306,389 - 2,319,034 (-)NCBIUU_Cfam_GSD_1.0

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:462
Count of miRNA genes:308
Interacting mature miRNAs:325
Transcripts:ENSMUST00000074557
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10045977Tir9_mtrypanosome infection response 9 (mouse)Not determined172787811943885114Mouse
26884379Skwq5_mskull length QTL 5, 5 week (mouse)173311897454107028Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
11075105Modc1_mmodifier of Odc1 (mouse)172771579245622654Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171506165249061760Mouse
15039348Nmrs37_mNAFLD-associated magnetic resonance shift 37 (mouse)172781520961815209Mouse
4141357Mrdq1_mmodifier of retinal degeneration QTL 1 (mouse)Not determined3098790348039703Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171681972150819843Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171087811944878219Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171914502553145025Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined485475245670266Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17858491442585149Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171264696146646961Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171506165249061760Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171746220851462345Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171746220851462345Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171746220851462345Mouse
4140955Plgr1_mplague resistance locus 1 (mouse)Not determined3103350065033630Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171506165249061760Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171746220851462345Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171702994351030078Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172605118560051352Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17689393640893936Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1188597145886119Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171245178746451787Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172507658355712970Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1120648439364059Mouse
10412196Bbaa28_mB.burgdorferi-associated arthritis 28 (mouse)Not determined172558491443976235Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17858491442585149Mouse
1302189Dps3_mdelta power in slow-wave sleep 3 (mouse)Not determined173381972136250180Mouse
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171841835752420983Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171817541252178214Mouse
1300692Blmpf1_mbleomycin-induced pulmonary fibrosis 1 (mouse)Not determined173206165237644775Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
12880399Sst6_msusceptibility to tuberculosis 6 (mouse)173446220834552681Mouse
1300703Uvbi2_mUVB induced immunosuppression 2 (mouse)Not determined172862240662622654Mouse
11038694Pas19_mpulmonary adenoma susceptibility 19 (mouse)172971116434754437Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171842214152424327Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172461275058612864Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171199818445998184Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172688497260885114Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
1300602Eye2_meye weight 2 (mouse)Not determined172650533741105037Mouse
25394538Skmw84_mskeletal muscle weight 84, TA (mouse)173266042635520036Mouse
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17334817537348299Mouse
1301759Sles1_msystemic lupus erythmatosus suppressor 1 (mouse)Not determined173421989035175937Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171681972150819843Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17485475246469702Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171506165249061760Mouse
1558758Kcal2_mkilocalorie 2 (mouse)Not determined172640101252911704Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171412337248123496Mouse
1300589Myaa2_mmodifier of Yaa 2 (mouse)Not determined173013255564132666Mouse

Markers in Region
H2-Eb1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371734,450,973 - 34,451,265UniSTSGRCm37
MGSCv371734,450,973 - 34,451,080UniSTSGRCm37
MGSCv371734,450,013 - 34,450,132UniSTSGRCm37
MGSCv371734,449,888 - 34,450,284UniSTSGRCm37
Celera1737,076,268 - 37,076,560UniSTS
Celera1737,076,268 - 37,076,375UniSTS
Celera1737,075,183 - 37,075,579UniSTS
Celera1737,075,308 - 37,075,427UniSTS
Cytogenetic Map17B1UniSTS
cM Map1718.66UniSTS
H2-Eb1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381734,314,028 - 34,314,135UniSTSGRCm38
MGSCv371734,450,973 - 34,451,080UniSTSGRCm37
Celera1737,076,268 - 37,076,375UniSTS
Cytogenetic Map17B1UniSTS
cM Map129.0UniSTS
cM Map865.5UniSTS
cM Map1917.5UniSTS
cM Map1718.66UniSTS
H2-Eb1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381734,313,068 - 34,313,187UniSTSGRCm38
MGSCv371734,450,013 - 34,450,132UniSTSGRCm37
Celera1737,075,308 - 37,075,427UniSTS
Cytogenetic Map17B1UniSTS
cM Map1718.66UniSTS
H2-Eb1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381734,314,028 - 34,314,320UniSTSGRCm38
MGSCv371734,450,973 - 34,451,265UniSTSGRCm37
Celera1737,076,268 - 37,076,560UniSTS
Cytogenetic Map17B1UniSTS
cM Map1718.66UniSTS
H2-Eb1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381734,312,943 - 34,313,339UniSTSGRCm38
MGSCv371734,449,888 - 34,450,284UniSTSGRCm37
Celera1737,075,183 - 37,075,579UniSTS
Cytogenetic Map17B1UniSTS
cM Map1718.66UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_010382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF050157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH002024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH002026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH002028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH005312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH005404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH005405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ492958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ492959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ492960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ492961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ492962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ492963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ492964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ493002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ493003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ493004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ493005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ493006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ493007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ493008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ493009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ493010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ493011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ493012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ634270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ634271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ634274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ634275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ634276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ634277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ634278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ717776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY611735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740486 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY740509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC132163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC132165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY202562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CAAA01111730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR974422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU424424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU468138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D90032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D90275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM443553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM443554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM443561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM443562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM443564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM443565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  K01145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KX981919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L15349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L15350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L38589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L38590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M11355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M12826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M14231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M14232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M14234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M14235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M14236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M14237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M28408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M28591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M36939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M36940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M37515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M73841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M73959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M73960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M74823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF629313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U13650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U13651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U13656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U28489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U28490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U88917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U88918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U88932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U88933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U88934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U88935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U88937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X00623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X00701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X00702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X00958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X07239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X52641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X52642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X54428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X86154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X86155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X86156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y13072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y13075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y13076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y13079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z69809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000074557   ⟹   ENSMUSP00000074143
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1734,524,991 - 34,535,173 (+)Ensembl
GRCm38.p6 Ensembl1734,306,017 - 34,316,199 (+)Ensembl
Ensembl Acc Id: ENSMUST00000235501
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1734,528,549 - 34,534,926 (+)Ensembl
GRCm38.p6 Ensembl1734,309,575 - 34,315,952 (+)Ensembl
Ensembl Acc Id: ENSMUST00000235530   ⟹   ENSMUSP00000158533
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1734,524,841 - 34,535,648 (+)Ensembl
GRCm38.p6 Ensembl1734,305,867 - 34,316,674 (+)Ensembl
Ensembl Acc Id: ENSMUST00000235729
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1734,524,908 - 34,533,557 (+)Ensembl
GRCm38.p6 Ensembl1734,305,934 - 34,314,583 (+)Ensembl
Ensembl Acc Id: ENSMUST00000236232   ⟹   ENSMUSP00000157594
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1734,524,900 - 34,535,173 (+)Ensembl
GRCm38.p6 Ensembl1734,305,926 - 34,316,199 (+)Ensembl
RefSeq Acc Id: NM_010382   ⟹   NP_034512
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391734,524,841 - 34,535,648 (+)NCBI
GRCm381734,305,867 - 34,316,674 (+)ENTREZGENE
MGSCv371734,442,812 - 34,453,619 (+)RGD
Celera1737,067,715 - 37,078,914 (+)RGD
cM Map17 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_034512 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA16542 (Get FASTA)   NCBI Sequence Viewer  
  AAA16543 (Get FASTA)   NCBI Sequence Viewer  
  AAA39586 (Get FASTA)   NCBI Sequence Viewer  
  AAA39589 (Get FASTA)   NCBI Sequence Viewer  
  AAA39590 (Get FASTA)   NCBI Sequence Viewer  
  AAA39591 (Get FASTA)   NCBI Sequence Viewer  
  AAA39593 (Get FASTA)   NCBI Sequence Viewer  
  AAA39594 (Get FASTA)   NCBI Sequence Viewer  
  AAA39595 (Get FASTA)   NCBI Sequence Viewer  
  AAA39606 (Get FASTA)   NCBI Sequence Viewer  
  AAA39639 (Get FASTA)   NCBI Sequence Viewer  
  AAA39640 (Get FASTA)   NCBI Sequence Viewer  
  AAA39641 (Get FASTA)   NCBI Sequence Viewer  
  AAA39642 (Get FASTA)   NCBI Sequence Viewer  
  AAA39643 (Get FASTA)   NCBI Sequence Viewer  
  AAA39644 (Get FASTA)   NCBI Sequence Viewer  
  AAA39645 (Get FASTA)   NCBI Sequence Viewer  
  AAB17688 (Get FASTA)   NCBI Sequence Viewer  
  AAB17689 (Get FASTA)   NCBI Sequence Viewer  
  AAB53282 (Get FASTA)   NCBI Sequence Viewer  
  AAB53283 (Get FASTA)   NCBI Sequence Viewer  
  AAB53297 (Get FASTA)   NCBI Sequence Viewer  
  AAB53298 (Get FASTA)   NCBI Sequence Viewer  
  AAB53299 (Get FASTA)   NCBI Sequence Viewer  
  AAB53300 (Get FASTA)   NCBI Sequence Viewer  
  AAB53302 (Get FASTA)   NCBI Sequence Viewer  
  AAB60680 (Get FASTA)   NCBI Sequence Viewer  
  AAB60681 (Get FASTA)   NCBI Sequence Viewer  
  AAC05286 (Get FASTA)   NCBI Sequence Viewer  
  AAC52533 (Get FASTA)   NCBI Sequence Viewer  
  AAC52534 (Get FASTA)   NCBI Sequence Viewer  
  AAI32164 (Get FASTA)   NCBI Sequence Viewer  
  AAI32166 (Get FASTA)   NCBI Sequence Viewer  
  AAT36825 (Get FASTA)   NCBI Sequence Viewer  
  AAU94606 (Get FASTA)   NCBI Sequence Viewer  
  AAU94608 (Get FASTA)   NCBI Sequence Viewer  
  AAU94609 (Get FASTA)   NCBI Sequence Viewer  
  AAU94610 (Get FASTA)   NCBI Sequence Viewer  
  AAU94611 (Get FASTA)   NCBI Sequence Viewer  
  AAU94612 (Get FASTA)   NCBI Sequence Viewer  
  AAU94613 (Get FASTA)   NCBI Sequence Viewer  
  AAU94615 (Get FASTA)   NCBI Sequence Viewer  
  AAU94616 (Get FASTA)   NCBI Sequence Viewer  
  AAU94617 (Get FASTA)   NCBI Sequence Viewer  
  AAU94618 (Get FASTA)   NCBI Sequence Viewer  
  AAU94619 (Get FASTA)   NCBI Sequence Viewer  
  AAU94620 (Get FASTA)   NCBI Sequence Viewer  
  AAU94621 (Get FASTA)   NCBI Sequence Viewer  
  AAU94622 (Get FASTA)   NCBI Sequence Viewer  
  AAU94623 (Get FASTA)   NCBI Sequence Viewer  
  AAU94624 (Get FASTA)   NCBI Sequence Viewer  
  AAU94625 (Get FASTA)   NCBI Sequence Viewer  
  AAU94626 (Get FASTA)   NCBI Sequence Viewer  
  AAU94627 (Get FASTA)   NCBI Sequence Viewer  
  AAU94628 (Get FASTA)   NCBI Sequence Viewer  
  AAU94629 (Get FASTA)   NCBI Sequence Viewer  
  AAU94630 (Get FASTA)   NCBI Sequence Viewer  
  AAU94631 (Get FASTA)   NCBI Sequence Viewer  
  AAU94632 (Get FASTA)   NCBI Sequence Viewer  
  ADQ37242 (Get FASTA)   NCBI Sequence Viewer  
  ADQ37243 (Get FASTA)   NCBI Sequence Viewer  
  ADQ37250 (Get FASTA)   NCBI Sequence Viewer  
  ADQ37252 (Get FASTA)   NCBI Sequence Viewer  
  ADQ37253 (Get FASTA)   NCBI Sequence Viewer  
  ATD50493 (Get FASTA)   NCBI Sequence Viewer  
  AWY63481 (Get FASTA)   NCBI Sequence Viewer  
  AWY63486 (Get FASTA)   NCBI Sequence Viewer  
  AWY63493 (Get FASTA)   NCBI Sequence Viewer  
  AWY63513 (Get FASTA)   NCBI Sequence Viewer  
  AWY63514 (Get FASTA)   NCBI Sequence Viewer  
  AWY63515 (Get FASTA)   NCBI Sequence Viewer  
  AWY63517 (Get FASTA)   NCBI Sequence Viewer  
  AWY63518 (Get FASTA)   NCBI Sequence Viewer  
  AWY63519 (Get FASTA)   NCBI Sequence Viewer  
  AWY63520 (Get FASTA)   NCBI Sequence Viewer  
  AWY63521 (Get FASTA)   NCBI Sequence Viewer  
  AWY63522 (Get FASTA)   NCBI Sequence Viewer  
  AWY63527 (Get FASTA)   NCBI Sequence Viewer  
  AWY63528 (Get FASTA)   NCBI Sequence Viewer  
  AWY63529 (Get FASTA)   NCBI Sequence Viewer  
  AWY63530 (Get FASTA)   NCBI Sequence Viewer  
  AWY63531 (Get FASTA)   NCBI Sequence Viewer  
  AWY63532 (Get FASTA)   NCBI Sequence Viewer  
  AWY63535 (Get FASTA)   NCBI Sequence Viewer  
  AWY63538 (Get FASTA)   NCBI Sequence Viewer  
  AWY63539 (Get FASTA)   NCBI Sequence Viewer  
  AWY63540 (Get FASTA)   NCBI Sequence Viewer  
  AWY63541 (Get FASTA)   NCBI Sequence Viewer  
  AWY63542 (Get FASTA)   NCBI Sequence Viewer  
  AWY63543 (Get FASTA)   NCBI Sequence Viewer  
  AWY63544 (Get FASTA)   NCBI Sequence Viewer  
  AWY63545 (Get FASTA)   NCBI Sequence Viewer  
  AWY63546 (Get FASTA)   NCBI Sequence Viewer  
  AWY63547 (Get FASTA)   NCBI Sequence Viewer  
  AWY63548 (Get FASTA)   NCBI Sequence Viewer  
  BAA14080 (Get FASTA)   NCBI Sequence Viewer  
  BAA14319 (Get FASTA)   NCBI Sequence Viewer  
  BAE33527 (Get FASTA)   NCBI Sequence Viewer  
  BAE35816 (Get FASTA)   NCBI Sequence Viewer  
  CAA25257 (Get FASTA)   NCBI Sequence Viewer  
  CAA25470 (Get FASTA)   NCBI Sequence Viewer  
  CAA30228 (Get FASTA)   NCBI Sequence Viewer  
  CAA36863 (Get FASTA)   NCBI Sequence Viewer  
  CAA36864 (Get FASTA)   NCBI Sequence Viewer  
  CAA38300 (Get FASTA)   NCBI Sequence Viewer  
  CAA73515 (Get FASTA)   NCBI Sequence Viewer  
  CAA73518 (Get FASTA)   NCBI Sequence Viewer  
  CAA73519 (Get FASTA)   NCBI Sequence Viewer  
  CAA73522 (Get FASTA)   NCBI Sequence Viewer  
  CAB51615 (Get FASTA)   NCBI Sequence Viewer  
  CAD37846 (Get FASTA)   NCBI Sequence Viewer  
  CAD37847 (Get FASTA)   NCBI Sequence Viewer  
  CAD37848 (Get FASTA)   NCBI Sequence Viewer  
  CAD37849 (Get FASTA)   NCBI Sequence Viewer  
  CAD37850 (Get FASTA)   NCBI Sequence Viewer  
  CAD37851 (Get FASTA)   NCBI Sequence Viewer  
  CAD37852 (Get FASTA)   NCBI Sequence Viewer  
  CAD37884 (Get FASTA)   NCBI Sequence Viewer  
  CAD37885 (Get FASTA)   NCBI Sequence Viewer  
  CAD37886 (Get FASTA)   NCBI Sequence Viewer  
  CAD37887 (Get FASTA)   NCBI Sequence Viewer  
  CAD37888 (Get FASTA)   NCBI Sequence Viewer  
  CAD37889 (Get FASTA)   NCBI Sequence Viewer  
  CAD37890 (Get FASTA)   NCBI Sequence Viewer  
  CAD37891 (Get FASTA)   NCBI Sequence Viewer  
  CAD37892 (Get FASTA)   NCBI Sequence Viewer  
  CAD37893 (Get FASTA)   NCBI Sequence Viewer  
  CAD37894 (Get FASTA)   NCBI Sequence Viewer  
  CAG24014 (Get FASTA)   NCBI Sequence Viewer  
  CAG24015 (Get FASTA)   NCBI Sequence Viewer  
  CAG24018 (Get FASTA)   NCBI Sequence Viewer  
  CAG24019 (Get FASTA)   NCBI Sequence Viewer  
  CAG24020 (Get FASTA)   NCBI Sequence Viewer  
  CAG24021 (Get FASTA)   NCBI Sequence Viewer  
  CAG24022 (Get FASTA)   NCBI Sequence Viewer  
  CAG30744 (Get FASTA)   NCBI Sequence Viewer  
  CAG30745 (Get FASTA)   NCBI Sequence Viewer  
  CAG30746 (Get FASTA)   NCBI Sequence Viewer  
  CAG30747 (Get FASTA)   NCBI Sequence Viewer  
  CAG30748 (Get FASTA)   NCBI Sequence Viewer  
  CAG30749 (Get FASTA)   NCBI Sequence Viewer  
  CAG30750 (Get FASTA)   NCBI Sequence Viewer  
  CAG30751 (Get FASTA)   NCBI Sequence Viewer  
  CAG30752 (Get FASTA)   NCBI Sequence Viewer  
  CAG30753 (Get FASTA)   NCBI Sequence Viewer  
  CAG30754 (Get FASTA)   NCBI Sequence Viewer  
  CAG30755 (Get FASTA)   NCBI Sequence Viewer  
  CAG30756 (Get FASTA)   NCBI Sequence Viewer  
  CAG30757 (Get FASTA)   NCBI Sequence Viewer  
  CAG30758 (Get FASTA)   NCBI Sequence Viewer  
  CAG30759 (Get FASTA)   NCBI Sequence Viewer  
  CAG30760 (Get FASTA)   NCBI Sequence Viewer  
  CAG30761 (Get FASTA)   NCBI Sequence Viewer  
  CAG30762 (Get FASTA)   NCBI Sequence Viewer  
  CAG30763 (Get FASTA)   NCBI Sequence Viewer  
  CAG30764 (Get FASTA)   NCBI Sequence Viewer  
  CAG30765 (Get FASTA)   NCBI Sequence Viewer  
  CAG30766 (Get FASTA)   NCBI Sequence Viewer  
  CAG30767 (Get FASTA)   NCBI Sequence Viewer  
  CAG30768 (Get FASTA)   NCBI Sequence Viewer  
  CAG30769 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000074143.10
  ENSMUSP00000157594.2
  ENSMUSP00000158533
  ENSMUSP00000158533.2
GenBank Protein P04230 (Get FASTA)   NCBI Sequence Viewer  
  P04231 (Get FASTA)   NCBI Sequence Viewer  
  P18468 (Get FASTA)   NCBI Sequence Viewer  
  P18469 (Get FASTA)   NCBI Sequence Viewer  
  P20040 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_034512   ⟸   NM_010382
- Peptide Label: precursor
- UniProtKB: P04230 (UniProtKB/Swiss-Prot),   O78226 (UniProtKB/Swiss-Prot),   O78196 (UniProtKB/TrEMBL),   F6VX29 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000157594   ⟸   ENSMUST00000236232
Ensembl Acc Id: ENSMUSP00000074143   ⟸   ENSMUST00000074557
Ensembl Acc Id: ENSMUSP00000158533   ⟸   ENSMUST00000235530
Protein Domains
Ig-like   Ig-like C1-type   MHC class II beta chain N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P01915-F1-model_v2 AlphaFold P01915 1-264 view protein structure
AF-P04230-F1-model_v2 AlphaFold P04230 1-264 view protein structure
AF-P20040-F1-model_v2 AlphaFold P20040 1-264 view protein structure

Promoters
RGD ID:13675686
Promoter ID:EPDNEW_M21992
Type:initiation region
Name:H2-Eb1_1
Description:Mus musculus histocompatibility 2, class II antigen E beta (H2-Eb1),mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381734,305,897 - 34,305,957EPDNEW
RGD ID:6828213
Promoter ID:MM_KWN:23180
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver,   Lung,   Spleen
Transcripts:NM_010382
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361734,441,846 - 34,443,012 (+)MPROMDB
RGD ID:6828210
Promoter ID:MM_KWN:23181
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Lung,   MEF_B4,   Spleen
Transcripts:ENSMUST00000074557,   UC008CCI.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361734,446,516 - 34,447,016 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95901 AgrOrtholog
Ensembl Genes ENSMUSG00000060586 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000074557.11 UniProtKB/TrEMBL
  ENSMUST00000235530 ENTREZGENE
  ENSMUST00000235530.2 UniProtKB/TrEMBL
  ENSMUST00000236232.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig/MHC_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_C1-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC/Immunoglobulin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I/II-like_Ag-recog UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_II_a/b_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_II_b_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14969 UniProtKB/TrEMBL
MGD MGI:95901 ENTREZGENE
NCBI Gene 14969 ENTREZGENE
PANTHER HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DRB1 BETA CHAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC CLASS II-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam C1-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_II_beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB HLA-DRB1 RGD
PhenoGen H2-Eb1 PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG_MHC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IGc1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_II_beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A068BET0_MOUSE UniProtKB/TrEMBL
  A0A068BFW3_MOUSE UniProtKB/TrEMBL
  A0A068BIU3_MOUSE UniProtKB/TrEMBL
  A0A2Z4SWY4_MOUSE UniProtKB/TrEMBL
  A0A2Z4SWZ4_MOUSE UniProtKB/TrEMBL
  A0A2Z4SWZ5_MOUSE UniProtKB/TrEMBL
  A0A2Z4SX03_MOUSE UniProtKB/TrEMBL
  A0A2Z4SX04_MOUSE UniProtKB/TrEMBL
  A0A2Z4SX15_MOUSE UniProtKB/TrEMBL
  A0A2Z4SX16_MOUSE UniProtKB/TrEMBL
  A0A2Z4SX25_MOUSE UniProtKB/TrEMBL
  A0A2Z4SX26_MOUSE UniProtKB/TrEMBL
  A0A2Z4SX33_MOUSE UniProtKB/TrEMBL
  A0A2Z4SX35_MOUSE UniProtKB/TrEMBL
  A0A2Z4SX43_MOUSE UniProtKB/TrEMBL
  A0A2Z4SX44_MOUSE UniProtKB/TrEMBL
  A0A2Z4SX53_MOUSE UniProtKB/TrEMBL
  A0A2Z4SX55_MOUSE UniProtKB/TrEMBL
  A0A2Z4SX62_MOUSE UniProtKB/TrEMBL
  A0A2Z4SX71_MOUSE UniProtKB/TrEMBL
  A0A2Z4SX81_MOUSE UniProtKB/TrEMBL
  A0A2Z4SX90_MOUSE UniProtKB/TrEMBL
  A0A2Z4SX95_MOUSE UniProtKB/TrEMBL
  A0A2Z4SXA1_MOUSE UniProtKB/TrEMBL
  A0A2Z4SXA6_MOUSE UniProtKB/TrEMBL
  A0A2Z4SXB0_MOUSE UniProtKB/TrEMBL
  A0A2Z4SXB5_MOUSE UniProtKB/TrEMBL
  A0A2Z4SXC6_MOUSE UniProtKB/TrEMBL
  A0A2Z4SXD5_MOUSE UniProtKB/TrEMBL
  A0A2Z4SXE7_MOUSE UniProtKB/TrEMBL
  A0A2Z4SXF7_MOUSE UniProtKB/TrEMBL
  A0A2Z4SY02_MOUSE UniProtKB/TrEMBL
  A0A2Z4SY11_MOUSE UniProtKB/TrEMBL
  A0A2Z4SY21_MOUSE UniProtKB/TrEMBL
  A0A2Z4SY32_MOUSE UniProtKB/TrEMBL
  A0A2Z4SY42_MOUSE UniProtKB/TrEMBL
  A0A2Z4SY53_MOUSE UniProtKB/TrEMBL
  A0A2Z4SY63_MOUSE UniProtKB/TrEMBL
  A0A2Z4SYI8_MOUSE UniProtKB/TrEMBL
  A0A2Z4SYJ8_MOUSE UniProtKB/TrEMBL
  A0A2Z4SYK9_MOUSE UniProtKB/TrEMBL
  A0A2Z4SYL9_MOUSE UniProtKB/TrEMBL
  A0A2Z4SYN0_MOUSE UniProtKB/TrEMBL
  A0A2Z4SYN7_MOUSE UniProtKB/TrEMBL
  A0A2Z4SYP0_MOUSE UniProtKB/TrEMBL
  A0A2Z4SYP9_MOUSE UniProtKB/TrEMBL
  A0A2Z4SYQ0_MOUSE UniProtKB/TrEMBL
  A0A2Z4SYQ8_MOUSE UniProtKB/TrEMBL
  A0A2Z4SYR6_MOUSE UniProtKB/TrEMBL
  A0A2Z4SYS8_MOUSE UniProtKB/TrEMBL
  A0A2Z4SYT7_MOUSE UniProtKB/TrEMBL
  A0A2Z4SYU4_MOUSE UniProtKB/TrEMBL
  A0A2Z4T150_MOUSE UniProtKB/TrEMBL
  A0A2Z4T159_MOUSE UniProtKB/TrEMBL
  A0A2Z4T169_MOUSE UniProtKB/TrEMBL
  A0A2Z4T178_MOUSE UniProtKB/TrEMBL
  A0A2Z4T188_MOUSE UniProtKB/TrEMBL
  A0A2Z4T196_MOUSE UniProtKB/TrEMBL
  A0A2Z4T1A9_MOUSE UniProtKB/TrEMBL
  A0A2Z4T247_MOUSE UniProtKB/TrEMBL
  A0A2Z4T259_MOUSE UniProtKB/TrEMBL
  A0A2Z4T270_MOUSE UniProtKB/TrEMBL
  A0A2Z4T282_MOUSE UniProtKB/TrEMBL
  A0A2Z4T292_MOUSE UniProtKB/TrEMBL
  A0A2Z4T2A8_MOUSE UniProtKB/TrEMBL
  A0A2Z4T2C0_MOUSE UniProtKB/TrEMBL
  A0A2Z4T356_MOUSE UniProtKB/TrEMBL
  A0A2Z4T368_MOUSE UniProtKB/TrEMBL
  A0A2Z4T379_MOUSE UniProtKB/TrEMBL
  A0A2Z4T389_MOUSE UniProtKB/TrEMBL
  A0A2Z4T397_MOUSE UniProtKB/TrEMBL
  A0A2Z4T3A7_MOUSE UniProtKB/TrEMBL
  A0A2Z4T3B6_MOUSE UniProtKB/TrEMBL
  A0A494B9C8_MOUSE UniProtKB/TrEMBL
  A0A498U6I0_MOUSE UniProtKB/TrEMBL
  F6VX29 ENTREZGENE
  HB21_MOUSE UniProtKB/Swiss-Prot
  HB23_MOUSE UniProtKB/Swiss-Prot
  HB24_MOUSE UniProtKB/Swiss-Prot
  HB2I_MOUSE UniProtKB/Swiss-Prot
  HB2J_MOUSE UniProtKB/Swiss-Prot
  O78196 ENTREZGENE, UniProtKB/TrEMBL
  O78226 ENTREZGENE
  P04230 ENTREZGENE
  P04231 ENTREZGENE
  P18468 ENTREZGENE
  P18469 ENTREZGENE
  P20040 ENTREZGENE
  Q31103_MOUSE UniProtKB/TrEMBL
  Q31104_MOUSE UniProtKB/TrEMBL
  Q31124_MOUSE UniProtKB/TrEMBL
  Q31161_MOUSE UniProtKB/TrEMBL
  Q31163_MOUSE UniProtKB/TrEMBL
  Q31164_MOUSE UniProtKB/TrEMBL
  Q31171_MOUSE UniProtKB/TrEMBL
  Q31185_MOUSE UniProtKB/TrEMBL
  Q31239_MOUSE UniProtKB/TrEMBL
  Q3U1H1_MOUSE UniProtKB/TrEMBL
  Q61713_MOUSE UniProtKB/TrEMBL
  Q61857_MOUSE UniProtKB/TrEMBL
UniProt Secondary F6VX29 UniProtKB/TrEMBL
  O78225 UniProtKB/Swiss-Prot
  O78226 UniProtKB/Swiss-Prot