LOC100995226 (HLA class II histocompatibility antigen, DP beta 1 chain) - Rat Genome Database

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Gene: LOC100995226 (HLA class II histocompatibility antigen, DP beta 1 chain) Pan paniscus
Analyze
Symbol: LOC100995226 (Ensembl: HLA-DPB1)
Name: HLA class II histocompatibility antigen, DP beta 1 chain (Ensembl:major histocompatibility complex, class II, DP beta 1)
RGD ID: 11671164
Description: ENCODES a protein that exhibits peptide antigen binding (inferred); INVOLVED IN adaptive immune response (inferred); antigen processing and presentation (inferred); antigen processing and presentation of exogenous peptide antigen via MHC class II (inferred); ASSOCIATED WITH allergic asthma (ortholog); angioedema (ortholog); anti-basement membrane glomerulonephritis (ortholog); FOUND IN cell surface (inferred); endosome (inferred); endosome membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DP beta 1 chain; DP beta chain 1; Papa-DPB1
RGD Orthologs
Human
Rat
Chinchilla
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2547,554,419 - 47,565,212 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1643,426,026 - 43,436,864 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0632,648,780 - 32,659,613 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1633,763,566 - 33,774,387 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl633,763,566 - 33,774,387 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
LOC100995226
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2547,554,419 - 47,565,212 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1643,426,026 - 43,436,864 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0632,648,780 - 32,659,613 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1633,763,566 - 33,774,387 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl633,763,566 - 33,774,387 (+)Ensemblpanpan1.1panPan2
HLA-DPB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38633,075,990 - 33,089,696 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl633,075,990 - 33,089,696 (+)EnsemblGRCh38hg38GRCh38
GRCh37633,043,767 - 33,057,473 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36633,151,738 - 33,162,954 (+)NCBINCBI36Build 36hg18NCBI36
Build 34633,151,737 - 33,162,954NCBI
Celera634,592,531 - 34,609,302 (+)NCBICelera
Cytogenetic Map6p21.32NCBI
HuRef632,786,143 - 32,799,913 (+)NCBIHuRef
CHM1_1633,045,380 - 33,059,156 (+)NCBICHM1_1
T2T-CHM13v2.0632,897,341 - 32,911,047 (+)NCBIT2T-CHM13v2.0
RT1-Hb-ps1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8204,777,494 - 4,781,486 (+)NCBIGRCr8
mRatBN7.2204,775,598 - 4,779,590 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl204,774,650 - 4,780,618 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0203,866,361 - 3,870,353 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl203,866,636 - 3,870,351 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0205,945,754 - 5,949,746 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,913,121 - 4,917,113 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera206,376,076 - 6,380,068 (+)NCBICelera
Cytogenetic Map20p12NCBI
LOC102026469
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554371,635,538 - 1,669,042 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554371,655,092 - 1,666,552 (+)NCBIChiLan1.0ChiLan1.0
LOC101963197
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494638,219,177 - 38,229,467 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647625,730,596 - 25,741,145 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647625,730,800 - 25,741,089 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MHC-DPB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11738,996,329 - 39,007,097 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604432,914,008 - 32,924,191 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101697345
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475423,658,339 - 23,672,663 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475423,661,031 - 23,672,549 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000060302   ⟹   ENSPPAP00000037402
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl633,763,566 - 33,774,387 (+)Ensembl
RefSeq Acc Id: XM_003808595   ⟹   XP_003808643
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2547,554,419 - 47,565,212 (+)NCBI
NHGRI_mPanPan1643,426,026 - 43,436,864 (+)NCBI
Mhudiblu_PPA_v0632,648,780 - 32,659,613 (+)NCBI
PanPan1.1633,763,566 - 33,774,387 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003808643   ⟸   XM_003808595
- UniProtKB: A0A2R9CGS3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000037402   ⟸   ENSPPAT00000060302
Protein Domains
Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000041449 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000060302.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig/MHC_CS UniProtKB/TrEMBL
  Ig_C1-set UniProtKB/TrEMBL
  MHC_I/II-like_Ag-recog UniProtKB/TrEMBL
  MHC_II_a/b_N UniProtKB/TrEMBL
  MHC_II_b_N UniProtKB/TrEMBL
KEGG Report pps:100995226 UniProtKB/TrEMBL
NCBI Gene LOC100995226 ENTREZGENE
PANTHER HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DP BETA 1 CHAIN UniProtKB/TrEMBL
  MHC CLASS II-RELATED UniProtKB/TrEMBL
Pfam C1-set UniProtKB/TrEMBL
  MHC_II_beta UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
  IG_MHC UniProtKB/TrEMBL
SMART IGc1 UniProtKB/TrEMBL
  MHC_II_beta UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
  SSF54452 UniProtKB/TrEMBL
UniProt A0A2R9CGS3 ENTREZGENE, UniProtKB/TrEMBL