LOC100972354 (interferon alpha-2) - Rat Genome Database

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Gene: LOC100972354 (interferon alpha-2) Pan paniscus
Analyze
Symbol: LOC100972354
Name: interferon alpha-2
RGD ID: 11974528
Description: INVOLVED IN defense response to virus (ortholog); negative regulation of gene expression (ortholog); negative regulation of interleukin-13 production (ortholog); ASSOCIATED WITH Abdominal Pain (ortholog); acute kidney failure (ortholog); adult T-cell leukemia (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: IFNA2; interferon alpha 2
RGD Orthologs
Human
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1921,862,557 - 21,863,690 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl921,863,062 - 21,863,736 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0921,245,017 - 21,246,210 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Abdominal Pain  (ISO)
acute kidney failure  (ISO)
adult T-cell leukemia  (ISO)
anemia  (ISO)
Anorexia  (ISO)
anterior ischemic optic neuropathy  (ISO)
anxiety disorder  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
Chills  (ISO)
Chronic Hepatitis  (ISO)
Chronic Hepatitis B  (ISO)
Chronic Hepatitis C  (ISO)
chronic myeloid leukemia  (ISO)
Colorectal Neoplasms  (ISO)
common cold  (ISO)
diarrhea  (ISO)
disease of mental health  (ISO)
Epithelioid Hemangioendothelioma  (ISO)
essential thrombocythemia  (ISO)
Experimental Liver Cirrhosis  (ISO)
Fatigue  (ISO)
fatty liver disease  (ISO)
Fever  (ISO)
Flavivirus Infections  (ISO)
follicular lymphoma  (ISO)
glioblastoma  (ISO)
Headache  (ISO)
hemolytic anemia  (ISO)
hepatitis B  (ISO)
hepatitis C  (ISO)
hepatocellular carcinoma  (ISO)
Hepatomegaly  (ISO)
Hodgkin's lymphoma  (ISO)
Hypertriglyceridemia  (ISO)
intestinal perforation  (ISO)
kidney failure  (ISO)
leukopenia  (ISO)
liver cirrhosis  (ISO)
melanoma  (ISO)
Meningism  (ISO)
mental depression  (ISO)
multiple myeloma  (ISO)
myocardial infarction  (ISO)
Nausea  (ISO)
neutropenia  (ISO)
non-alcoholic fatty liver disease  (ISO)
non-Hodgkin lymphoma  (ISO)
Pain  (ISO)
pancreatic cancer  (ISO)
polycythemia vera  (ISO)
Polyomavirus Infections  (ISO)
pterygium  (ISO)
Raynaud disease  (ISO)
renal cell carcinoma  (ISO)
retinal detachment  (ISO)
retinal disease  (ISO)
schizophrenia  (ISO)
Sepsis  (ISO)
skin disease  (ISO)
somatoform disorder  (ISO)
squamous cell carcinoma  (ISO)
Stevens-Johnson syndrome  (ISO)
stomatitis  (ISO)
thrombocytopenia  (ISO)
Thyroid Neoplasms  (ISO)
Tinnitus  (ISO)
transitional cell carcinoma  (ISO)
urinary bladder cancer  (ISO)
Viremia  (ISO)
Vogt-Koyanagi-Harada disease  (ISO)
Vomiting  (ISO)
Weight Gain  (ISO)
Weight Loss  (ISO)
withdrawal disorder  (ISO)

References

Genomics

Comparative Map Data
LOC100972354
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1921,862,557 - 21,863,690 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl921,863,062 - 21,863,736 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0921,245,017 - 21,246,210 (-)NCBIMhudiblu_PPA_v0panPan3
IFNA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl921,384,255 - 21,385,398 (-)EnsemblGRCh38hg38GRCh38
GRCh38921,384,255 - 21,385,398 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37921,384,254 - 21,385,397 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36921,374,254 - 21,375,396 (-)NCBINCBI36hg18NCBI36
Build 34921,374,253 - 21,375,396NCBI
Celera921,322,568 - 21,323,710 (-)NCBI
Cytogenetic Map9p21.3NCBI
HuRef921,347,656 - 21,348,798 (-)NCBIHuRef
CHM1_1921,384,072 - 21,385,214 (-)NCBICHM1_1
IFNA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11258,468,018 - 58,469,825 (+)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003830676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide SSBP01000193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000023181   ⟹   ENSPPAP00000005073
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl921,863,062 - 21,863,736 (-)Ensembl
RefSeq Acc Id: XM_003830676   ⟹   XP_003830724
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1921,862,557 - 21,863,690 (-)NCBI
Mhudiblu_PPA_v0921,245,017 - 21,246,210 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003830724 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003830724   ⟸   XM_003830676
- Sequence:
RefSeq Acc Id: ENSPPAP00000005073   ⟸   ENSPPAT00000023181


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000021138 Ensembl, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000005073 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000023181 UniProtKB/TrEMBL
InterPro 4_helix_cytokine-like_core UniProtKB/TrEMBL
  Interferon_alpha/beta/delta UniProtKB/TrEMBL
NCBI Gene IFNA2 ENTREZGENE
PANTHER PTHR11691 UniProtKB/TrEMBL
Pfam Interferon UniProtKB/TrEMBL
PRINTS INTERFERONAB UniProtKB/TrEMBL
SMART IFabd UniProtKB/TrEMBL
Superfamily-SCOP SSF47266 UniProtKB/TrEMBL
UniProt A0A2R8ZJA8_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-07-01 LOC100972354  interferon alpha-2  IFNA2  interferon alpha 2  Symbol and/or name change 5135510 APPROVED