TLR9 (toll like receptor 9) - Rat Genome Database

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Gene: TLR9 (toll like receptor 9) Homo sapiens
Analyze
Symbol: TLR9
Name: toll like receptor 9
RGD ID: 1346715
HGNC Page HGNC
Description: Enables interleukin-1 receptor binding activity and siRNA binding activity. Involved in several processes, including regulation of B cell activation; regulation of gene expression; and regulation of signal transduction. Located in apical plasma membrane; basolateral plasma membrane; and cytoplasm. Implicated in several diseases, including allergic bronchopulmonary aspergillosis; cystic fibrosis; glomerulonephritis (multiple); hepatitis B; and lung disease (multiple). Biomarker of several diseases, including Human papillomavirus infectious disease; anogenital venereal wart; liver disease (multiple); lung disease (multiple); and nose disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD289; toll-like receptor 9
RGD Orthologs
Mouse
Rat
Chinchilla
Dog
Pig
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl352,221,080 - 52,225,645 (-)EnsemblGRCh38hg38GRCh38
GRCh38352,221,080 - 52,225,645 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37352,255,096 - 52,259,661 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36352,230,138 - 52,235,219 (-)NCBINCBI36hg18NCBI36
Build 34352,230,137 - 52,233,247NCBI
Celera352,234,410 - 52,239,491 (-)NCBI
Cytogenetic Map3p21.2NCBI
HuRef352,317,258 - 52,322,341 (-)NCBIHuRef
CHM1_1352,207,624 - 52,212,707 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Achlorhydria  (IAGP)
acute kidney failure  (ISO)
acute necrotizing pancreatitis  (ISO)
adult respiratory distress syndrome  (ISO)
alcoholic liver cirrhosis  (IEP)
allergic bronchopulmonary aspergillosis  (IAGP,ISO)
allergic conjunctivitis  (IEP)
allergic rhinitis  (IEP)
anogenital venereal wart  (IEP)
asthma  (IAGP,IEP,ISO)
bacterial pneumonia  (ISO)
Brain Injuries  (EXP)
breast cancer  (IEP)
bronchiolitis obliterans  (IAGP)
cardiovascular system disease  (IAGP)
cervix uteri carcinoma in situ  (IEP)
Chemical and Drug Induced Liver Injury  (IEP,ISO)
chronic granulomatous disease  (IEP)
Chronic Hepatitis B  (IAGP,IEP)
Chronic Hepatitis C  (IEP)
chronic kidney disease  (IAGP)
Chronic Periodontitis  (IEP)
crescentic glomerulonephritis  (ISO)
Crohn's disease  (EXP)
cutaneous leishmaniasis  (IEP)
cystic fibrosis  (IAGP)
dermatomyositis  (IEP)
Experimental Autoimmune Neuritis  (ISO)
Granuloma, Foreign-Body  (EXP)
Hearing Loss  (IAGP)
hepatitis B  (IAGP)
hepatitis C  (IAGP,IEP)
hepatocellular carcinoma  (EXP,IEP,IMP)
Herpes Simplex Encephalitis  (ISO)
herpes simplex virus keratitis  (ISO)
Hypergammaglobulinemia  (ISO)
IgA glomerulonephritis  (IAGP,ISO)
Inflammation  (EXP)
interstitial lung disease  (IEP)
Klebsiella Infections  (ISO)
Legionnaires' disease  (ISO)
Liver Injury  (ISO)
Lung Neoplasms  (IEP)
lung non-small cell carcinoma  (IEP)
lupus nephritis  (IAGP,IEP,ISO)
Malarial Anemia  (IAGP)
mastitis  (ISO)
membranoproliferative glomerulonephritis  (ISO)
non-alcoholic fatty liver disease  (IEP)
non-alcoholic steatohepatitis  (ISO)
Oral Lichen Planus  (IEP)
papillomavirus infectious disease  (IEP)
perinatal necrotizing enterocolitis  (ISO)
Pneumococcal Infections  (ISO)
Pneumococcal Meningitis  (ISO)
primary biliary cholangitis  (IEP)
proteinuria  (IAGP,ISO)
pulmonary fibrosis  (IEP)
pulmonary tuberculosis  (IAGP)
renal cell carcinoma  (IEP)
Respiratory Sounds  (IAGP)
Respiratory Tract Granuloma  (EXP,ISO)
Schistosomiasis Mansoni  (EXP)
sinusitis  (IEP)
squamous cell carcinoma  (IEP)
systemic lupus erythematosus  (IAGP,ISO)
Tracheoesophageal Fistula  (IAGP)
Transplant Rejection  (IAGP)
Triple Negative Breast Neoplasms  (EXP)
trypanosomiasis  (ISO)
ureteral obstruction  (ISO)
viral pneumonia  (IAGP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of innate immune response  (ISO)
cellular response to chloroquine  (ISO)
cellular response to lipopolysaccharide  (ISO)
cellular response to metal ion  (ISO)
defense response to bacterium  (NAS)
defense response to Gram-negative bacterium  (IMP)
defense response to virus  (IBA,ISO)
I-kappaB kinase/NF-kappaB signaling  (IBA)
I-kappaB phosphorylation  (IDA)
immune response  (ISO)
inflammatory response  (IEA)
innate immune response  (TAS)
maintenance of gastrointestinal epithelium  (ISS)
male gonad development  (ISO)
microglial cell activation  (ISO)
MyD88-dependent toll-like receptor signaling pathway  (IEA)
negative regulation of ATPase-coupled calcium transmembrane transporter activity  (IDA)
negative regulation of ERK1 and ERK2 cascade  (ISO)
negative regulation of interleukin-6 production  (ISS)
negative regulation of interleukin-8 production  (IDA)
negative regulation of NF-kappaB transcription factor activity  (IDA)
negative regulation of toll-like receptor signaling pathway  (IDA)
positive regulation of autophagy  (ISO)
positive regulation of B cell activation  (IDA)
positive regulation of B cell proliferation  (IDA)
positive regulation of chemokine production  (IDA)
positive regulation of cytokine production  (ISO)
positive regulation of gene expression  (IDA)
positive regulation of granulocyte macrophage colony-stimulating factor production  (IDA)
positive regulation of I-kappaB kinase/NF-kappaB signaling  (IDA)
positive regulation of immunoglobulin production  (IDA)
positive regulation of inflammatory response  (IC)
positive regulation of interferon-alpha production  (IDA)
positive regulation of interferon-beta production  (IDA,ISS)
positive regulation of interferon-gamma production  (IDA)
positive regulation of interleukin-10 production  (ISS)
positive regulation of interleukin-12 production  (ISS)
positive regulation of interleukin-18 production  (ISS)
positive regulation of interleukin-6 production  (IBA,IDA)
positive regulation of interleukin-8 production  (IDA)
positive regulation of JNK cascade  (IC)
positive regulation of JUN kinase activity  (IDA)
positive regulation of MAPK cascade  (IDA)
positive regulation of NF-kappaB transcription factor activity  (IBA,IDA)
positive regulation of NIK/NF-kappaB signaling  (IDA)
positive regulation of nitric-oxide synthase biosynthetic process  (ISS)
positive regulation of toll-like receptor 9 signaling pathway  (ISO)
positive regulation of toll-like receptor signaling pathway  (IDA)
positive regulation of transcription by RNA polymerase II  (ISS)
positive regulation of tumor necrosis factor production  (ISS)
regulation of B cell activation  (ISO)
regulation of B cell differentiation  (IDA)
regulation of dendritic cell cytokine production  (ISO)
regulation of inflammatory response  (ISO)
regulation of protein phosphorylation  (ISO)
regulation of toll-like receptor 9 signaling pathway  (IDA)
response to molecule of bacterial origin  (TAS)
response to virus  (ISO)
toll-like receptor 9 signaling pathway  (IEA)
toll-like receptor signaling pathway  (IBA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
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Additional References at PubMed
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PMID:21604257   PMID:21607583   PMID:21633947   PMID:21682079   PMID:21689850   PMID:21703981   PMID:21720175   PMID:21734566   PMID:21741080   PMID:21748790   PMID:21778270   PMID:21778277  
PMID:21823020   PMID:21833528   PMID:21843566   PMID:21844166   PMID:21850017   PMID:21866115   PMID:21873635   PMID:21876325   PMID:21903422   PMID:21908428   PMID:21911421   PMID:21926972  
PMID:21940676   PMID:21968308   PMID:21968713   PMID:21977996   PMID:21978158   PMID:21990957   PMID:22001237   PMID:22014045   PMID:22041559   PMID:22046272   PMID:22055432   PMID:22057691  
PMID:22059466   PMID:22065095   PMID:22067623   PMID:22070100   PMID:22132241   PMID:22169598   PMID:22170068   PMID:22174451   PMID:22178715   PMID:22196370   PMID:22207622   PMID:22211722  
PMID:22221660   PMID:22228476   PMID:22269973   PMID:22288832   PMID:22344539   PMID:22423970   PMID:22427638   PMID:22488361   PMID:22552867   PMID:22554506   PMID:22577991   PMID:22594374  
PMID:22594608   PMID:22613717   PMID:22653776   PMID:22671429   PMID:22684144   PMID:22691414   PMID:22695187   PMID:22701693   PMID:22714906   PMID:22768144   PMID:22822061   PMID:22836641  
PMID:22847512   PMID:22853846   PMID:22893852   PMID:22898741   PMID:22908309   PMID:22931661   PMID:22932083   PMID:22948021   PMID:22948541   PMID:22952899   PMID:22964787   PMID:23009111  
PMID:23021866   PMID:23043436   PMID:23071157   PMID:23091345   PMID:23103284   PMID:23123793   PMID:23133627   PMID:23135998   PMID:23179584   PMID:23182970   PMID:23183093   PMID:23219390  
PMID:23221735   PMID:23237868   PMID:23266611   PMID:23276930   PMID:23289794   PMID:23296704   PMID:23369718   PMID:23383065   PMID:23406596   PMID:23407387   PMID:23425749   PMID:23467704  
PMID:23472199   PMID:23490285   PMID:23497207   PMID:23564191   PMID:23592712   PMID:23593431   PMID:23617757   PMID:23651260   PMID:23673637   PMID:23677790   PMID:23711330   PMID:23724117  
PMID:23731219   PMID:23752229   PMID:23758740   PMID:23766695   PMID:23776537   PMID:23816930   PMID:23826189   PMID:23827939   PMID:23855294   PMID:23857366   PMID:23893288   PMID:23913633  
PMID:23953621   PMID:23957925   PMID:23962979   PMID:23964786   PMID:23967355   PMID:23974051   PMID:23974872   PMID:23990988   PMID:23994589   PMID:24004541   PMID:24007656   PMID:24053111  
PMID:24067965   PMID:24080302   PMID:24091496   PMID:24168509   PMID:24176007   PMID:24184955   PMID:24212717   PMID:24269682   PMID:24301797   PMID:24375473   PMID:24390332   PMID:24409285  
PMID:24459426   PMID:24470136   PMID:24504675   PMID:24532514   PMID:24571477   PMID:24574405   PMID:24582318   PMID:24610369   PMID:24612681   PMID:24647486   PMID:24658023   PMID:24692849  
PMID:24709112   PMID:24722226   PMID:24747071   PMID:24788552   PMID:24801457   PMID:24801688   PMID:24865418   PMID:24886842   PMID:24906089   PMID:24912772   PMID:24919757   PMID:24987851  
PMID:24990399   PMID:24993857   PMID:25037760   PMID:25068657   PMID:25081715   PMID:25098409   PMID:25121361   PMID:25124588   PMID:25133733   PMID:25182168   PMID:25187653   PMID:25187660  
PMID:25194054   PMID:25224571   PMID:25244363   PMID:25248338   PMID:25293716   PMID:25309919   PMID:25318894   PMID:25333705   PMID:25338738   PMID:25339018   PMID:25373689   PMID:25385499  
PMID:25400780   PMID:25444819   PMID:25454809   PMID:25466615   PMID:25473100   PMID:25480557   PMID:25499923   PMID:25561051   PMID:25586463   PMID:25605370   PMID:25616954   PMID:25660181  
PMID:25662572   PMID:25735984   PMID:25744504   PMID:25780037   PMID:25790192   PMID:25796310   PMID:25844529   PMID:25862837   PMID:25889916   PMID:25891128   PMID:25892310   PMID:25892855  
PMID:25912131   PMID:25941114   PMID:25948535   PMID:25967142   PMID:25995217   PMID:26000920   PMID:26003847   PMID:26028230   PMID:26067373   PMID:26087186   PMID:26164937   PMID:26270118  
PMID:26307434   PMID:26313906   PMID:26339055   PMID:26340429   PMID:26361369   PMID:26371257   PMID:26371589   PMID:26416273   PMID:26426362   PMID:26462624   PMID:26466955   PMID:26504005  
PMID:26505293   PMID:26525587   PMID:26563540   PMID:26568059   PMID:26569074   PMID:26613957   PMID:26620361   PMID:26632396   PMID:26643792   PMID:26648480   PMID:26680366   PMID:26723518  
PMID:26759164   PMID:26762473   PMID:26780557   PMID:26903634   PMID:26934958   PMID:26938157   PMID:27018624   PMID:27026438   PMID:27045344   PMID:27075928   PMID:27105145   PMID:27122592  
PMID:27157617   PMID:27196570   PMID:27221282   PMID:27252169   PMID:27277333   PMID:27288485   PMID:27346696   PMID:27390897   PMID:27392462   PMID:27398910   PMID:27424138   PMID:27432810  
PMID:27432908   PMID:27474073   PMID:27492306   PMID:27498757   PMID:27525854   PMID:27538656   PMID:27566084   PMID:27590109   PMID:27668411   PMID:27716055   PMID:27744078   PMID:27765276  
PMID:27768958   PMID:27793667   PMID:27941651   PMID:27993530   PMID:28049380   PMID:28061462   PMID:28083607   PMID:28093541   PMID:28106541   PMID:28115525   PMID:28151579   PMID:28191612  
PMID:28202935   PMID:28246611   PMID:28255201   PMID:28295589   PMID:28321710   PMID:28340580   PMID:28346226   PMID:28433888   PMID:28445304   PMID:28459195   PMID:28487240   PMID:28497211  
PMID:28500897   PMID:28518215   PMID:28528372   PMID:28530246   PMID:28544067   PMID:28594360   PMID:28622534   PMID:28703296   PMID:28724760   PMID:28762092   PMID:28763101   PMID:28819773  
PMID:28834234   PMID:28886076   PMID:28916728   PMID:28973009   PMID:28988039   PMID:29030552   PMID:29053005   PMID:29076114   PMID:29088270   PMID:29097808   PMID:29101363   PMID:29147913  
PMID:29157732   PMID:29228322   PMID:29276096   PMID:29286214   PMID:29290528   PMID:29363775   PMID:29437897   PMID:29458158   PMID:29476183   PMID:29515028   PMID:29543867   PMID:29675696  
PMID:29697393   PMID:29755476   PMID:29860675   PMID:29880709   PMID:29883450   PMID:29895224   PMID:29901280   PMID:29934589   PMID:29945961   PMID:29968427   PMID:30021884   PMID:30057921  
PMID:30185518   PMID:30215163   PMID:30218032   PMID:30239236   PMID:30239551   PMID:30277474   PMID:30321082   PMID:30345020   PMID:30348730   PMID:30357962   PMID:30373864   PMID:30424735  
PMID:30431116   PMID:30508414   PMID:30587483   PMID:30610847   PMID:30651082   PMID:30745168   PMID:30793925   PMID:30824926   PMID:30846988   PMID:31002145   PMID:31170232   PMID:31278284  
PMID:31279905   PMID:31300344   PMID:31317790   PMID:31335975   PMID:31355328   PMID:31365550   PMID:31379843   PMID:31380807   PMID:31385869   PMID:31450898   PMID:31470365   PMID:31521407  
PMID:31534550   PMID:31571275   PMID:31647295   PMID:31681284   PMID:31781672   PMID:31851971   PMID:31879046   PMID:31886298   PMID:31889719   PMID:32054102   PMID:32173390   PMID:32173534  
PMID:32205444   PMID:32372371   PMID:32547554   PMID:32638255   PMID:32658127   PMID:32729323   PMID:32753695   PMID:32871478   PMID:32939755   PMID:32967147   PMID:33143777   PMID:33247440  
PMID:33354779   PMID:33369094   PMID:33372855   PMID:33382388   PMID:33389882   PMID:33472905   PMID:33643304   PMID:33800897   PMID:33939072   PMID:33994431   PMID:34161457   PMID:34216052  
PMID:34416273   PMID:34456901  


Genomics

Comparative Map Data
TLR9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl352,221,080 - 52,225,645 (-)EnsemblGRCh38hg38GRCh38
GRCh38352,221,080 - 52,225,645 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37352,255,096 - 52,259,661 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36352,230,138 - 52,235,219 (-)NCBINCBI36hg18NCBI36
Build 34352,230,137 - 52,233,247NCBI
Celera352,234,410 - 52,239,491 (-)NCBI
Cytogenetic Map3p21.2NCBI
HuRef352,317,258 - 52,322,341 (-)NCBIHuRef
CHM1_1352,207,624 - 52,212,707 (-)NCBICHM1_1
Tlr9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399106,099,797 - 106,104,075 (+)NCBIGRCm39mm39
GRCm39 Ensembl9106,099,797 - 106,104,082 (+)Ensembl
GRCm389106,222,598 - 106,226,876 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9106,222,598 - 106,226,883 (+)EnsemblGRCm38mm10GRCm38
MGSCv379106,124,929 - 106,129,207 (+)NCBIGRCm37mm9NCBIm37
MGSCv369106,080,699 - 106,084,977 (+)NCBImm8
Celera9105,848,890 - 105,853,167 (+)NCBICelera
Cytogenetic Map9F1NCBI
Tlr9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28106,864,680 - 106,868,796 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl8106,864,680 - 106,868,796 (+)Ensembl
Rnor_6.08114,916,122 - 114,920,171 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8114,916,122 - 114,920,171 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08114,279,020 - 114,283,069 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera8106,185,754 - 106,189,869 (+)NCBICelera
Cytogenetic Map8q32NCBI
Tlr9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555323,828,645 - 3,832,699 (-)NCBIChiLan1.0ChiLan1.0
TLR9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12037,529,322 - 37,547,117 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2037,542,340 - 37,547,114 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2037,529,401 - 37,539,957 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2037,510,887 - 37,521,504 (+)NCBI
Dog10K_Boxer_Tasha2037,523,889 - 37,528,666 (+)NCBI
ROS_Cfam_1.02037,879,856 - 37,897,682 (+)NCBI
UMICH_Zoey_3.12037,256,577 - 37,261,354 (+)NCBI
UMICH_Zoey_3.12037,243,558 - 37,254,192 (+)NCBI
UNSW_CanFamBas_1.02037,652,111 - 37,662,740 (+)NCBI
UNSW_CanFamBas_1.02037,665,125 - 37,669,902 (+)NCBI
UU_Cfam_GSD_1.02037,936,949 - 37,947,576 (+)NCBI
UU_Cfam_GSD_1.02037,950,172 - 37,954,949 (+)NCBI
TLR9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11334,353,444 - 34,370,990 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21337,634,343 - 37,652,036 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Position Markers
PMC128073P9  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37352,257,646 - 52,257,876UniSTSGRCh37
Build 36352,232,686 - 52,232,916RGDNCBI36
Celera352,236,958 - 52,237,188RGD
Cytogenetic Map3p21.3UniSTS
HuRef352,319,808 - 52,320,038UniSTS
PMC55404P4  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37352,257,916 - 52,258,175UniSTSGRCh37
Build 36352,232,956 - 52,233,215RGDNCBI36
Celera352,237,228 - 52,237,487RGD
Cytogenetic Map3p21.3UniSTS
HuRef352,320,078 - 52,320,337UniSTS
TLR9_1094  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37352,255,183 - 52,256,079UniSTSGRCh37
Build 36352,230,223 - 52,231,119RGDNCBI36
Celera352,234,495 - 52,235,391RGD
HuRef352,317,345 - 52,318,241UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:609
Count of miRNA genes:290
Interacting mature miRNAs:301
Transcripts:ENST00000360658, ENST00000597542
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 39 282 7 367 5 3 22 11 7 5
Low 1983 2022 977 183 824 44 3468 1660 2732 57 1101 1165 139 1080 2414
Below cutoff 225 654 526 271 469 249 624 484 847 109 150 158 25 124 367 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_033933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_017442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB045180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB445673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC097637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF245704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF246972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF259262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF259263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY359085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC032713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ019992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ019993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ019994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ019995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ019996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ019997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ019998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ019999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU170539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU170540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU170541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU170542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU170543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ946863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ946864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ946865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ946866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ946867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ946868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ946869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ946870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ946871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ946872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ946873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ946874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ946875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ946876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HF584053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC624802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322486 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322568 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322592 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG322604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000360658   ⟹   ENSP00000353874
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl352,221,080 - 52,225,645 (-)Ensembl
RefSeq Acc Id: NM_017442   ⟹   NP_059138
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38352,221,080 - 52,225,645 (-)NCBI
GRCh37352,255,096 - 52,260,179 (-)ENTREZGENE
Build 36352,230,138 - 52,235,219 (-)NCBI Archive
HuRef352,317,258 - 52,322,341 (-)ENTREZGENE
CHM1_1352,207,624 - 52,212,707 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_059138 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF72189 (Get FASTA)   NCBI Sequence Viewer  
  AAF72190 (Get FASTA)   NCBI Sequence Viewer  
  AAF78037 (Get FASTA)   NCBI Sequence Viewer  
  AAG01734 (Get FASTA)   NCBI Sequence Viewer  
  AAH32713 (Get FASTA)   NCBI Sequence Viewer  
  AAQ89443 (Get FASTA)   NCBI Sequence Viewer  
  AAZ95513 (Get FASTA)   NCBI Sequence Viewer  
  AAZ95514 (Get FASTA)   NCBI Sequence Viewer  
  AAZ95515 (Get FASTA)   NCBI Sequence Viewer  
  AAZ95516 (Get FASTA)   NCBI Sequence Viewer  
  AAZ95517 (Get FASTA)   NCBI Sequence Viewer  
  AAZ95518 (Get FASTA)   NCBI Sequence Viewer  
  AAZ95519 (Get FASTA)   NCBI Sequence Viewer  
  AAZ95520 (Get FASTA)   NCBI Sequence Viewer  
  ABW37074 (Get FASTA)   NCBI Sequence Viewer  
  ABW37075 (Get FASTA)   NCBI Sequence Viewer  
  ABW37076 (Get FASTA)   NCBI Sequence Viewer  
  ABW37077 (Get FASTA)   NCBI Sequence Viewer  
  ABW37078 (Get FASTA)   NCBI Sequence Viewer  
  ACQ41818 (Get FASTA)   NCBI Sequence Viewer  
  ACQ41819 (Get FASTA)   NCBI Sequence Viewer  
  ACQ41820 (Get FASTA)   NCBI Sequence Viewer  
  ACQ41821 (Get FASTA)   NCBI Sequence Viewer  
  ACQ41822 (Get FASTA)   NCBI Sequence Viewer  
  ACQ41823 (Get FASTA)   NCBI Sequence Viewer  
  ACQ41824 (Get FASTA)   NCBI Sequence Viewer  
  ACQ41825 (Get FASTA)   NCBI Sequence Viewer  
  ACQ41826 (Get FASTA)   NCBI Sequence Viewer  
  ACQ41827 (Get FASTA)   NCBI Sequence Viewer  
  ACQ41828 (Get FASTA)   NCBI Sequence Viewer  
  ACQ41829 (Get FASTA)   NCBI Sequence Viewer  
  ACQ41830 (Get FASTA)   NCBI Sequence Viewer  
  ACQ41831 (Get FASTA)   NCBI Sequence Viewer  
  AVX47207 (Get FASTA)   NCBI Sequence Viewer  
  AVX47208 (Get FASTA)   NCBI Sequence Viewer  
  AVX47209 (Get FASTA)   NCBI Sequence Viewer  
  AVX47210 (Get FASTA)   NCBI Sequence Viewer  
  AVX47211 (Get FASTA)   NCBI Sequence Viewer  
  AVX47212 (Get FASTA)   NCBI Sequence Viewer  
  AVX47213 (Get FASTA)   NCBI Sequence Viewer  
  AVX47214 (Get FASTA)   NCBI Sequence Viewer  
  AVX47215 (Get FASTA)   NCBI Sequence Viewer  
  AVX47216 (Get FASTA)   NCBI Sequence Viewer  
  AVX47217 (Get FASTA)   NCBI Sequence Viewer  
  AVX47218 (Get FASTA)   NCBI Sequence Viewer  
  AVX47219 (Get FASTA)   NCBI Sequence Viewer  
  AVX47220 (Get FASTA)   NCBI Sequence Viewer  
  AVX47221 (Get FASTA)   NCBI Sequence Viewer  
  AVX47222 (Get FASTA)   NCBI Sequence Viewer  
  AVX47223 (Get FASTA)   NCBI Sequence Viewer  
  AVX47224 (Get FASTA)   NCBI Sequence Viewer  
  AVX47225 (Get FASTA)   NCBI Sequence Viewer  
  AVX47226 (Get FASTA)   NCBI Sequence Viewer  
  AVX47227 (Get FASTA)   NCBI Sequence Viewer  
  AVX47228 (Get FASTA)   NCBI Sequence Viewer  
  AVX47229 (Get FASTA)   NCBI Sequence Viewer  
  AVX47230 (Get FASTA)   NCBI Sequence Viewer  
  AVX47231 (Get FASTA)   NCBI Sequence Viewer  
  AVX47232 (Get FASTA)   NCBI Sequence Viewer  
  AVX47233 (Get FASTA)   NCBI Sequence Viewer  
  AVX47234 (Get FASTA)   NCBI Sequence Viewer  
  AVX47235 (Get FASTA)   NCBI Sequence Viewer  
  AVX47236 (Get FASTA)   NCBI Sequence Viewer  
  AVX47237 (Get FASTA)   NCBI Sequence Viewer  
  AVX47238 (Get FASTA)   NCBI Sequence Viewer  
  AVX47239 (Get FASTA)   NCBI Sequence Viewer  
  AVX47240 (Get FASTA)   NCBI Sequence Viewer  
  AVX47241 (Get FASTA)   NCBI Sequence Viewer  
  AVX47242 (Get FASTA)   NCBI Sequence Viewer  
  AVX47243 (Get FASTA)   NCBI Sequence Viewer  
  AVX47244 (Get FASTA)   NCBI Sequence Viewer  
  AVX47245 (Get FASTA)   NCBI Sequence Viewer  
  AVX47246 (Get FASTA)   NCBI Sequence Viewer  
  AVX47247 (Get FASTA)   NCBI Sequence Viewer  
  AVX47248 (Get FASTA)   NCBI Sequence Viewer  
  AVX47249 (Get FASTA)   NCBI Sequence Viewer  
  AVX47250 (Get FASTA)   NCBI Sequence Viewer  
  AVX47251 (Get FASTA)   NCBI Sequence Viewer  
  AVX47252 (Get FASTA)   NCBI Sequence Viewer  
  AVX47253 (Get FASTA)   NCBI Sequence Viewer  
  AVX47254 (Get FASTA)   NCBI Sequence Viewer  
  AVX47255 (Get FASTA)   NCBI Sequence Viewer  
  AVX47256 (Get FASTA)   NCBI Sequence Viewer  
  AVX47257 (Get FASTA)   NCBI Sequence Viewer  
  AVX47258 (Get FASTA)   NCBI Sequence Viewer  
  AVX47259 (Get FASTA)   NCBI Sequence Viewer  
  AVX47260 (Get FASTA)   NCBI Sequence Viewer  
  AVX47261 (Get FASTA)   NCBI Sequence Viewer  
  AVX47262 (Get FASTA)   NCBI Sequence Viewer  
  AVX47263 (Get FASTA)   NCBI Sequence Viewer  
  AVX47264 (Get FASTA)   NCBI Sequence Viewer  
  AVX47265 (Get FASTA)   NCBI Sequence Viewer  
  AVX47266 (Get FASTA)   NCBI Sequence Viewer  
  AVX47267 (Get FASTA)   NCBI Sequence Viewer  
  AVX47268 (Get FASTA)   NCBI Sequence Viewer  
  AVX47269 (Get FASTA)   NCBI Sequence Viewer  
  AVX47270 (Get FASTA)   NCBI Sequence Viewer  
  AVX47271 (Get FASTA)   NCBI Sequence Viewer  
  AVX47272 (Get FASTA)   NCBI Sequence Viewer  
  AVX47273 (Get FASTA)   NCBI Sequence Viewer  
  AVX47274 (Get FASTA)   NCBI Sequence Viewer  
  AVX47275 (Get FASTA)   NCBI Sequence Viewer  
  AVX47276 (Get FASTA)   NCBI Sequence Viewer  
  AVX47277 (Get FASTA)   NCBI Sequence Viewer  
  AVX47278 (Get FASTA)   NCBI Sequence Viewer  
  AVX47279 (Get FASTA)   NCBI Sequence Viewer  
  AVX47280 (Get FASTA)   NCBI Sequence Viewer  
  AVX47281 (Get FASTA)   NCBI Sequence Viewer  
  AVX47282 (Get FASTA)   NCBI Sequence Viewer  
  AVX47283 (Get FASTA)   NCBI Sequence Viewer  
  AVX47284 (Get FASTA)   NCBI Sequence Viewer  
  AVX47285 (Get FASTA)   NCBI Sequence Viewer  
  AVX47286 (Get FASTA)   NCBI Sequence Viewer  
  AVX47287 (Get FASTA)   NCBI Sequence Viewer  
  AVX47288 (Get FASTA)   NCBI Sequence Viewer  
  AVX47289 (Get FASTA)   NCBI Sequence Viewer  
  AVX47290 (Get FASTA)   NCBI Sequence Viewer  
  AVX47291 (Get FASTA)   NCBI Sequence Viewer  
  AVX47292 (Get FASTA)   NCBI Sequence Viewer  
  AVX47293 (Get FASTA)   NCBI Sequence Viewer  
  AVX47294 (Get FASTA)   NCBI Sequence Viewer  
  AVX47295 (Get FASTA)   NCBI Sequence Viewer  
  AVX47296 (Get FASTA)   NCBI Sequence Viewer  
  AVX47297 (Get FASTA)   NCBI Sequence Viewer  
  AVX47298 (Get FASTA)   NCBI Sequence Viewer  
  AVX47299 (Get FASTA)   NCBI Sequence Viewer  
  AVX47300 (Get FASTA)   NCBI Sequence Viewer  
  AVX47301 (Get FASTA)   NCBI Sequence Viewer  
  AVX47302 (Get FASTA)   NCBI Sequence Viewer  
  AVX47303 (Get FASTA)   NCBI Sequence Viewer  
  AVX47304 (Get FASTA)   NCBI Sequence Viewer  
  AVX47305 (Get FASTA)   NCBI Sequence Viewer  
  AVX47306 (Get FASTA)   NCBI Sequence Viewer  
  AVX47307 (Get FASTA)   NCBI Sequence Viewer  
  AVX47308 (Get FASTA)   NCBI Sequence Viewer  
  AVX47309 (Get FASTA)   NCBI Sequence Viewer  
  AVX47310 (Get FASTA)   NCBI Sequence Viewer  
  AVX47311 (Get FASTA)   NCBI Sequence Viewer  
  AVX47312 (Get FASTA)   NCBI Sequence Viewer  
  AVX47313 (Get FASTA)   NCBI Sequence Viewer  
  AVX47314 (Get FASTA)   NCBI Sequence Viewer  
  AVX47315 (Get FASTA)   NCBI Sequence Viewer  
  AVX47316 (Get FASTA)   NCBI Sequence Viewer  
  AVX47317 (Get FASTA)   NCBI Sequence Viewer  
  AVX47318 (Get FASTA)   NCBI Sequence Viewer  
  AVX47319 (Get FASTA)   NCBI Sequence Viewer  
  AVX47320 (Get FASTA)   NCBI Sequence Viewer  
  AVX47321 (Get FASTA)   NCBI Sequence Viewer  
  AVX47322 (Get FASTA)   NCBI Sequence Viewer  
  AVX47323 (Get FASTA)   NCBI Sequence Viewer  
  AVX47324 (Get FASTA)   NCBI Sequence Viewer  
  AVX47325 (Get FASTA)   NCBI Sequence Viewer  
  AVX47326 (Get FASTA)   NCBI Sequence Viewer  
  AVX47327 (Get FASTA)   NCBI Sequence Viewer  
  AVX47328 (Get FASTA)   NCBI Sequence Viewer  
  AVX47329 (Get FASTA)   NCBI Sequence Viewer  
  AVX47330 (Get FASTA)   NCBI Sequence Viewer  
  AVX47331 (Get FASTA)   NCBI Sequence Viewer  
  AVX47332 (Get FASTA)   NCBI Sequence Viewer  
  AVX47333 (Get FASTA)   NCBI Sequence Viewer  
  AVX47334 (Get FASTA)   NCBI Sequence Viewer  
  AVX47335 (Get FASTA)   NCBI Sequence Viewer  
  AVX47336 (Get FASTA)   NCBI Sequence Viewer  
  AVX47337 (Get FASTA)   NCBI Sequence Viewer  
  AVX47338 (Get FASTA)   NCBI Sequence Viewer  
  AVX47339 (Get FASTA)   NCBI Sequence Viewer  
  AVX47340 (Get FASTA)   NCBI Sequence Viewer  
  AVX47341 (Get FASTA)   NCBI Sequence Viewer  
  AVX47342 (Get FASTA)   NCBI Sequence Viewer  
  AVX47343 (Get FASTA)   NCBI Sequence Viewer  
  AVX47344 (Get FASTA)   NCBI Sequence Viewer  
  AVX47345 (Get FASTA)   NCBI Sequence Viewer  
  AVX47346 (Get FASTA)   NCBI Sequence Viewer  
  AVX47347 (Get FASTA)   NCBI Sequence Viewer  
  AVX47348 (Get FASTA)   NCBI Sequence Viewer  
  AVX47349 (Get FASTA)   NCBI Sequence Viewer  
  AVX47350 (Get FASTA)   NCBI Sequence Viewer  
  AVX47351 (Get FASTA)   NCBI Sequence Viewer  
  BAB19259 (Get FASTA)   NCBI Sequence Viewer  
  BAG55070 (Get FASTA)   NCBI Sequence Viewer  
  CCQ43550 (Get FASTA)   NCBI Sequence Viewer  
  EAW65191 (Get FASTA)   NCBI Sequence Viewer  
  EAW65193 (Get FASTA)   NCBI Sequence Viewer  
  Q9NR96 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_059138   ⟸   NM_017442
- Peptide Label: precursor
- UniProtKB: Q9NR96 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000353874   ⟸   ENST00000360658
Protein Domains
TIR

Promoters
RGD ID:6864614
Promoter ID:EPDNEW_H5472
Type:initiation region
Name:TLR9_2
Description:toll like receptor 9
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H5473  EPDNEW_H5474  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38352,222,215 - 52,222,275EPDNEW
RGD ID:6864616
Promoter ID:EPDNEW_H5473
Type:initiation region
Name:TLR9_1
Description:toll like receptor 9
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H5472  EPDNEW_H5474  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38352,225,636 - 52,225,696EPDNEW
RGD ID:6864618
Promoter ID:EPDNEW_H5474
Type:multiple initiation site
Name:TLR9_3
Description:toll like receptor 9
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H5472  EPDNEW_H5473  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38352,226,275 - 52,226,335EPDNEW
RGD ID:6801785
Promoter ID:HG_KWN:45207
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_017442
Position:
Human AssemblyChrPosition (strand)Source
Build 36352,234,746 - 52,235,857 (-)MPROMDB
RGD ID:6801783
Promoter ID:HG_KWN:45208
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   Lymphoblastoid
Transcripts:UC003DDB.1,   UC003DDC.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36352,238,681 - 52,239,827 (-)MPROMDB

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 3p21.31-14.3(chr3:49461000-55314500)x1 copy number loss See cases [RCV000051511] Chr3:49461000..55314500 [GRCh38]
Chr3:49498433..55348528 [GRCh37]
Chr3:49473437..55323568 [NCBI36]
Chr3:3p21.31-14.3
pathogenic
NM_017442.3(TLR9):c.1540G>A (p.Gly514Ser) single nucleotide variant Malignant melanoma [RCV000066137] Chr3:52222776 [GRCh38]
Chr3:52256792 [GRCh37]
Chr3:52231832 [NCBI36]
Chr3:3p21.2
not provided
NM_017442.3(TLR9):c.2185G>A (p.Glu729Lys) single nucleotide variant Malignant melanoma [RCV000060846] Chr3:52222131 [GRCh38]
Chr3:52256147 [GRCh37]
Chr3:52231187 [NCBI36]
Chr3:3p21.2
not provided
GRCh38/hg38 3p21.2-14.3(chr3:51394434-55064449)x1 copy number loss See cases [RCV000143631] Chr3:51394434..55064449 [GRCh38]
Chr3:51431865..55098476 [GRCh37]
Chr3:51406905..55073516 [NCBI36]
Chr3:3p21.2-14.3
likely pathogenic
GRCh37/hg19 3p21.2-14.2(chr3:52086599-59689209)x1 copy number loss See cases [RCV000239886] Chr3:52086599..59689209 [GRCh37]
Chr3:3p21.2-14.2
pathogenic
GRCh37/hg19 3p21.2(chr3:52257338-52264976)x3 copy number gain See cases [RCV000449360] Chr3:52257338..52264976 [GRCh37]
Chr3:3p21.2
likely benign
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986) copy number gain See cases [RCV000512358] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3 copy number gain See cases [RCV000511055] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3 copy number gain not provided [RCV000742138] Chr3:61495..197838262 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3 copy number gain not provided [RCV000742133] Chr3:60174..197948027 [GRCh37]
Chr3:3p26.3-q29
pathogenic
NM_017442.3(TLR9):c.1711G>A (p.Val571Met) single nucleotide variant not provided [RCV000884426] Chr3:52222605 [GRCh38]
Chr3:52256621 [GRCh37]
Chr3:3p21.2
likely benign
NM_017442.3(TLR9):c.2151C>A (p.Ala717=) single nucleotide variant not provided [RCV000881869] Chr3:52222165 [GRCh38]
Chr3:52256181 [GRCh37]
Chr3:3p21.2
likely benign
NM_017442.3(TLR9):c.441C>A (p.Ser147=) single nucleotide variant not provided [RCV000881115] Chr3:52223875 [GRCh38]
Chr3:52257891 [GRCh37]
Chr3:3p21.2
benign
NM_017442.3(TLR9):c.696C>T (p.Ile232=) single nucleotide variant not provided [RCV000949692] Chr3:52223620 [GRCh38]
Chr3:52257636 [GRCh37]
Chr3:3p21.2
benign
NM_017442.3(TLR9):c.192T>C (p.Asn64=) single nucleotide variant not provided [RCV000885053] Chr3:52224124 [GRCh38]
Chr3:52258140 [GRCh37]
Chr3:3p21.2
likely benign
NM_017442.3(TLR9):c.3093C>T (p.Ala1031=) single nucleotide variant not provided [RCV000886122] Chr3:52221223 [GRCh38]
Chr3:52255239 [GRCh37]
Chr3:3p21.2
benign
NM_017442.3(TLR9):c.1929C>T (p.Leu643=) single nucleotide variant not provided [RCV000925203] Chr3:52222387 [GRCh38]
Chr3:52256403 [GRCh37]
Chr3:3p21.2
likely benign
NM_017442.3(TLR9):c.1644G>A (p.Glu548=) single nucleotide variant not provided [RCV000941502] Chr3:52222672 [GRCh38]
Chr3:52256688 [GRCh37]
Chr3:3p21.2
likely benign
NM_017442.3(TLR9):c.13C>T (p.Arg5Cys) single nucleotide variant not provided [RCV000971495] Chr3:52224303 [GRCh38]
Chr3:52258319 [GRCh37]
Chr3:3p21.2
benign
GRCh37/hg19 3p21.31-21.1(chr3:45153770-53878616) copy number gain not provided [RCV000767704] Chr3:45153770..53878616 [GRCh37]
Chr3:3p21.31-21.1
pathogenic
NM_017442.3(TLR9):c.1800G>T (p.Leu600=) single nucleotide variant not provided [RCV000914864] Chr3:52222516 [GRCh38]
Chr3:52256532 [GRCh37]
Chr3:3p21.2
likely benign
GRCh37/hg19 3p21.2-21.1(chr3:52195134-52869037)x1 copy number loss not provided [RCV000848455] Chr3:52195134..52869037 [GRCh37]
Chr3:3p21.2-21.1
pathogenic
GRCh37/hg19 3p21.2-21.1(chr3:51247306-53069942)x3 copy number gain not provided [RCV001005434] Chr3:51247306..53069942 [GRCh37]
Chr3:3p21.2-21.1
uncertain significance
NM_017442.3(TLR9):c.1262A>T (p.Asp421Val) single nucleotide variant not provided [RCV000959560] Chr3:52223054 [GRCh38]
Chr3:52257070 [GRCh37]
Chr3:3p21.2
likely benign
NM_017442.3(TLR9):c.2412G>A (p.Gln804=) single nucleotide variant not provided [RCV000912388] Chr3:52221904 [GRCh38]
Chr3:52255920 [GRCh37]
Chr3:3p21.2
benign
NM_017442.3(TLR9):c.1689C>T (p.Gly563=) single nucleotide variant not provided [RCV000911602] Chr3:52222627 [GRCh38]
Chr3:52256643 [GRCh37]
Chr3:3p21.2
benign
NM_017442.3(TLR9):c.2588G>A (p.Arg863Gln) single nucleotide variant not provided [RCV000956636] Chr3:52221728 [GRCh38]
Chr3:52255744 [GRCh37]
Chr3:3p21.2
benign
NM_017442.3(TLR9):c.1527G>A (p.Ser509=) single nucleotide variant not provided [RCV000956765] Chr3:52222789 [GRCh38]
Chr3:52256805 [GRCh37]
Chr3:3p21.2
benign
NM_017442.3(TLR9):c.1149G>A (p.Thr383=) single nucleotide variant not provided [RCV000956766] Chr3:52223167 [GRCh38]
Chr3:52257183 [GRCh37]
Chr3:3p21.2
benign
NM_017442.3(TLR9):c.548C>G (p.Pro183Arg) single nucleotide variant Tracheoesophageal fistula [RCV001172304] Chr3:52223768 [GRCh38]
Chr3:52257784 [GRCh37]
Chr3:3p21.2
likely pathogenic
GRCh37/hg19 3p21.2-21.1(chr3:51975459-52561678)x4 copy number gain not provided [RCV001259685] Chr3:51975459..52561678 [GRCh37]
Chr3:3p21.2-21.1
uncertain significance

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:15633 AgrOrtholog
COSMIC TLR9 COSMIC
Ensembl Genes ENSG00000239732 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSP00000353874 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000360658 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.10140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
GTEx ENSG00000239732 GTEx
HGNC ID HGNC:15633 ENTREZGENE
Human Proteome Map TLR9 Human Proteome Map
InterPro Leu-rich_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_12 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  TIR_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TLR9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Toll_tir_struct_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:54106 UniProtKB/Swiss-Prot
NCBI Gene 54106 ENTREZGENE
OMIM 605474 OMIM
PANTHER PTHR47410:SF3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam LRR_12 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA38010 PharmGKB
PROSITE LRR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART LRR_TYP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52200 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2R4P858_HUMAN UniProtKB/TrEMBL
  A0A2R4P8E0_HUMAN UniProtKB/TrEMBL
  B6CH46_HUMAN UniProtKB/TrEMBL
  C3W5P5_HUMAN UniProtKB/TrEMBL
  D1CS61_HUMAN UniProtKB/TrEMBL
  D1CS62_HUMAN UniProtKB/TrEMBL
  L0R5D6_HUMAN UniProtKB/TrEMBL
  L8E8B9_HUMAN UniProtKB/TrEMBL
  Q9NR96 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary B3Y661 UniProtKB/Swiss-Prot
  D1CS56 UniProtKB/Swiss-Prot
  Q6UVZ2 UniProtKB/Swiss-Prot
  Q9HD68 UniProtKB/Swiss-Prot
  Q9HD69 UniProtKB/Swiss-Prot
  Q9HD70 UniProtKB/Swiss-Prot
  Q9NYC2 UniProtKB/Swiss-Prot
  Q9NYC3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-26 TLR9  toll like receptor 9    toll-like receptor 9  Symbol and/or name change 5135510 APPROVED
2011-08-16 TLR9  toll-like receptor 9  TLR9  toll-like receptor 9  Symbol and/or name change 5135510 APPROVED