Gene: Mir100 (microRNA 100) Mus musculus
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Symbol:
Mir100
Name:
microRNA 100
Description:
Involved in several processes, including cellular response to forskolin; cellular response to leukemia inhibitory factor; and long-term synaptic potentiation. Localizes to the synapse. Is expressed in embryo and lung.
Type:
ncrna
RefSeq Status:
PROVISIONAL
Also known as:
mir-100; Mirn100; mmu-mir-100
Orthologs:
Latest Assembly:
GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm38 9 41,531,425 - 41,531,504 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 MGSCv37 9 41,339,508 - 41,339,587 (+) NCBI GRCm37 mm9 NCBIm37 Celera 9 38,770,225 - 38,770,304 (+) NCBI Celera Cytogenetic Map 9 A5.1 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - CTD
Alzheimer's disease ISO RGD:1345382 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:25992776 Animal Mammary Neoplasms ISO RGD:1345382 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:24447120 Chemical and Drug Induced Liver Injury ISO RGD:1345382 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:28545106 Disease Progression ISO RGD:1345382 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:30026881 glomerulonephritis ISO RGD:1345382 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:25758243 hepatitis B ISO RGD:1345382 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:28545106 Neoplasm Metastasis ISO RGD:1345382 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:19487542 pancreatitis ISO RGD:1345382 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:27840954 transitional cell carcinoma ISO RGD:1345382 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:30026881 urinary bladder cancer ISO RGD:1345382 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:30026881
Gene-Chemical Interaction Annotations
17beta-hydroxy-5alpha-androstan-3-one decreases expression ISO RGD:1345382 6480464 Dihydrotestosterone results in decreased expression of MIR100 mRNA CTD PMID:25846647 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1345382 6480464 Tetrachlorodibenzodioxin results in increased expression of MIR100 mRNA CTD PMID:30096437 arsenous acid increases expression ISO RGD:1345382 6480464 Arsenic Trioxide results in increased expression of MIR100 mRNA CTD PMID:22072212 bleomycin A2 decreases expression ISO RGD:2325389 6480464 Bleomycin results in decreased expression of MIR100 mRNA CTD PMID:25933445 diarsenic trioxide increases expression ISO RGD:1345382 6480464 Arsenic Trioxide results in increased expression of MIR100 mRNA CTD PMID:22072212 formaldehyde decreases expression ISO RGD:1345382 6480464 Formaldehyde results in decreased expression of MIR100 mRNA CTD PMID:21147603 hydrogen peroxide increases expression ISO RGD:1345382 6480464 Hydrogen Peroxide results in increased expression of MIR100 mRNA CTD PMID:26339600 methapyrilene affects expression ISO RGD:2325389 6480464 Methapyrilene affects the expression of MIR100 mRNA CTD PMID:24863736 microcystin-LR decreases expression ISO RGD:1345382 6480464 cyanoginosin LR results in decreased expression of MIR100 mRNA CTD PMID:29518473 nitrofen increases expression ISO RGD:2325389 6480464 nitrofen results in increased expression of MIR100 mRNA CTD PMID:26720608 paracetamol increases expression ISO RGD:1345382 6480464 Acetaminophen results in increased expression of MIR100 mRNA CTD PMID:25092309 , PMID:28545106 paracetamol affects expression ISO RGD:2325389 6480464 Acetaminophen affects the expression of MIR100 mRNA CTD PMID:24863736 progesterone decreases expression ISO RGD:1345382 6480464 Progesterone results in decreased expression of MIR100 mRNA CTD PMID:22950660 resveratrol increases expression ISO RGD:1345382 6480464 Resveratrol results in increased expression of MIR100 mRNA CTD PMID:22016468 sodium arsenite increases expression ISO RGD:1345382 6480464 sodium arsenite results in increased expression of MIR100 mRNA CTD PMID:29207610 streptozocin decreases expression EXP 6480464 Streptozocin results in decreased expression of MIR100 mRNA CTD PMID:27629361 zinc atom decreases expression ISO RGD:2325389 6480464 Zinc deficiency results in decreased expression of MIR100 mRNA CTD PMID:22689922 zinc(0) decreases expression ISO RGD:2325389 6480464 Zinc deficiency results in decreased expression of MIR100 mRNA CTD PMID:22689922
Gene Ontology Annotations
Biological Process
cellular hyperosmotic salinity response IDA 2290270 (MGI:MGI:3691268, PMID:17028171) MGI MGI:MGI:3691268 , PMID:17028171 cellular response to forskolin IEP 2290270 (MGI:MGI:5305371, PMID:21993888) MGI MGI:MGI:5305371 , PMID:21993888 cellular response to inorganic substance IDA 2290270 (MGI:MGI:5305371, PMID:21993888) MGI MGI:MGI:5305371 , PMID:21993888 cellular response to leukemia inhibitory factor IEP 2290270 (MGI:MGI:4822296, PMID:20439489) MGI MGI:MGI:4822296 , PMID:20439489 gene silencing by miRNA IDA 2290270 (MGI:MGI:4822296, PMID:20439489) MGI MGI:MGI:4822296 , PMID:20439489 long-term synaptic potentiation IEP 2290270 (MGI:MGI:5645435, PMID:25858512) MGI MGI:MGI:5645435 , PMID:25858512 myelination IDA 2290270 (MGI:MGI:4830414, PMID:20805985) MGI MGI:MGI:4830414 , PMID:20805985 positive regulation of stem cell differentiation IMP 2290270 (MGI:MGI:4822296, PMID:20439489) MGI MGI:MGI:4822296 , PMID:20439489 sensory perception of sound IEP 2290270 (MGI:MGI:5508842, PMID:23646144) MGI MGI:MGI:5508842 , PMID:23646144
Cellular Component
synapse IDA 2290270 (MGI:MGI:5449129, PMID:22897173) MGI MGI:MGI:5449129 , PMID:22897173
13504833 Bglu19_m blood glucose level 19 (mouse) 9 9999472 43999472 Mouse 1300532 Tbs2_m tuberculosis severity 2 (mouse) Not determined 9 12458674 46458818 Mouse 10043917 Obq37_m obesity QTL 37 (mouse) Not determined 9 13479879 47479879 Mouse 1357637 Si5lq2_m serum IGFBP-5 level QTL 2 (mouse) Not determined 9 15500455 49500594 Mouse 4141447 Cfmq2_m cystic fibrosis modifier QTL 2 (mouse) Not determined 9 15500455 49500594 Mouse 4141591 Cq4_m cholesterol QTL 4 (mouse) Not determined 9 15500455 49500594 Mouse 1301421 Lgth4_m body length 4 (mouse) Not determined 9 15500455 49500594 Mouse 11354951 Pdcc3_m plasmacytoid dentritic cell compartment 3 (mouse) 9 15838331 49838331 Mouse 12790993 Adq1_m aortic diameter QTL 1 (mouse) 9 15838331 49838331 Mouse 12790997 Adq2_m aortic diameter QTL 2 (mouse) 9 15838331 49838331 Mouse 12880415 V125Dq7_m vitamin D active form serum level QTL 7 (mouse) 9 16100000 50100000 Mouse 12880416 V125Dq8_m vitamin D active form serum level QTL 8 (mouse) 9 16100000 50100000 Mouse 13504834 Hdlq109_m HDL QTL 109 (mouse) 9 16798345 50798345 Mouse 1357465 Vtbt6_m vertebral trabecular bone trait 6 (mouse) Not determined 9 17067544 51067647 Mouse 1300643 Pvcan2_m protection against vaginal candidiasis 2 (mouse) Not determined 9 20032110 54032229 Mouse 1301439 Morph2_m morphine antinociception 2 (mouse) Not determined 9 20242066 54242196 Mouse 1301045 Sluc10_m susceptibility to lung cancer 10 (mouse) Not determined 9 20394901 54395074 Mouse 1301883 Skull12_m skull morphology 12 (mouse) Not determined 9 20394901 54395074 Mouse 4142352 Lmr17_m leishmaniasis resistance 17 (mouse) Not determined 9 20394901 54395074 Mouse 10043950 Pbft5_m percent body fat 5 (mouse) Not determined 9 20394901 54395074 Mouse 12904939 Edlmmq8_m extensor digitorum longus muscle mass QTL 8 (mouse) 9 20941444 54941444 Mouse 13208563 Bmiq8_m body mass index QTL 8 (mouse) 9 25000000 69000000 Mouse 11532694 Sluc39a_m susceptibility to lung cancer 39a (mouse) 9 25676189 59676285 Mouse 11532695 Sluc39b_m susceptibility to lung cancer 39b (mouse) 9 25676189 59676285 Mouse 11532696 Sluc39c_m susceptibility to lung cancer 39c (mouse) 9 25676189 59676285 Mouse 11532712 Sluc39d_m susceptibility to lung cancer 39d (mouse) 9 25676189 59676285 Mouse 1300932 Hdlq17_m HDL QTL 17 (mouse) Not determined 9 26885124 60885255 Mouse 10043867 Mtbcq9_m multiple trait body composition QTL 9 (mouse) Not determined 9 26885124 60885255 Mouse 10043987 Stheal13_m soft tissue heal 13 (mouse) Not determined 9 26885124 60885255 Mouse 10043878 Adip20_m adiposity 20 (mouse) Not determined 9 27339897 61340026 Mouse 1301000 Obq5_m obesity QTL 5 (mouse) Not determined 9 28592037 41888030 Mouse 10043847 Hdlq89_m HDL QTL 89 (mouse) Not determined 9 29381631 63381774 Mouse 1301782 Chol11_m cholesterol 11 (mouse) Not determined 9 29381631 63381774 Mouse 1301365 Ap5q_m alcohol preference 5 QTL (mouse) Not determined 9 30141866 64141979 Mouse 1357746 Vtbt7_m vertebral trabecular bone trait 7 (mouse) Not determined 9 30828617 64828723 Mouse 1302180 Actd4_m activity-distance traveled 4 (mouse) Not determined 9 32523263 66523557 Mouse 4141148 Cq5_m cholesterol QTL 5 (mouse) Not determined 9 32541121 66541246 Mouse 1301692 Hts_m hypothermia sensitivity (mouse) Not determined 9 32599872 66600121 Mouse 4141323 Ptnu3_m proteinuria 3 (mouse) Not determined 9 32978402 66978536 Mouse 1357709 Si5lq3_m serum IGFBP-5 level QTL 3 (mouse) Not determined 9 33199725 67199840 Mouse 1558872 Ibdq1_m inflammatory bowel disease QTL 1 (mouse) Not determined 9 34067544 73531973 Mouse 1357682 Phdlc1_m plasma HDL cholesterol 1 (mouse) Not determined 9 34193323 42853570 Mouse 1301252 Etohc3_m ethanol consumption 3 (mouse) Not determined 9 35123178 69123299 Mouse 1301972 Cocrb8_m cocaine related behavior 8 (mouse) Not determined 9 35123178 69123299 Mouse 1558968 Tbdr1_m body temperature response to dietary restriction, QTL 1 (mouse) Not determined 9 35123178 69123299 Mouse 10045613 Rapop7_m radiation-induced apoptosis 6 (mouse) Not determined 9 36824947 49509211 Mouse 1301501 Lmr2_m leishmaniasis resistance 2 (mouse) Not determined 9 37032110 50199840 Mouse 1301007 Pid2_m prion incubation determinant 2 (mouse) Not determined 9 37242066 44340026 Mouse 4142042 Alpq3_m alcohol preference QTL 3 (mouse) Not determined 9 37394901 98819654 Mouse 10043971 Obq32_m obesity QTL 32 (mouse) Not determined 9 37912244 71912244 Mouse 12791002 Arlsq2_m aortic root lesion size QTL 2 (mouse) 9 38192291 72192291 Mouse 12790986 Pcho9_m plasma cholesterol 9 (mouse) 9 38192291 72192291 Mouse 12790992 Arlsq1_m aortic root lesion size QTL 1 (mouse) 9 38192291 72192291 Mouse 12738449 Spcq2_m sperm count QTL 2 (mouse) 9 39492601 73492601 Mouse 1558993 Tdmq1_m type 2 diabetes modifying QTL 1 (mouse) Not determined 9 40508298 51897370 Mouse 4141071 Ath29_m atherosclerosis 29 (mouse) Not determined 9 40508298 74700643 Mouse 11532693 Sluc39_m susceptibility to lung cancer 39 (mouse) 9 40734078 48440176 Mouse 1301702 Brm1_m brachyury modifier 1 (mouse) Not determined 9 40897764 74897921 Mouse 12738415 Lfibq8_m liver fibrosis QTL 8 (mouse) 9 41490866 45432445 Mouse
Confirmed Targets
Smarca5 mmu-miR-100-5p Mirecords external_info NA NA 20439489 Mtor mmu-miR-100-5p OncomiRDB external_info NA NA 23292834 Plk1 mmu-miR-100-5p OncomiRDB external_info NA NA 23151088 Plk1 mmu-miR-100-5p OncomiRDB external_info NA NA 22249248 Plk1 mmu-miR-100-5p OncomiRDB external_info NA NA 22246341 Plk1 mmu-miR-100-5p OncomiRDB external_info NA NA 22120675 Smarca5 mmu-miR-100-5p OncomiRDB external_info NA NA 21212412 Atm mmu-miR-100-5p OncomiRDB external_info NA NA 20869334 Igf1r mmu-miR-100-5p OncomiRDB external_info NA NA 20484036 Plk1 mmu-miR-100-5p OncomiRDB external_info NA NA 19739117 Ctdspl mmu-miR-100-5p OncomiRDB external_info NA NA 21643017
Predicted Targets
Count of predictions: 10507 Count of gene targets: 5619 Count of transcripts: 8759 Interacting mature miRNAs: mmu-miR-100-3p, mmu-miR-100-5p Prediction methods: Microtar, Miranda, Pita, Rnahybrid, Targetscan Result types: miRGate_prediction