TREM1 (triggering receptor expressed on myeloid cells 1) - Rat Genome Database

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Gene: TREM1 (triggering receptor expressed on myeloid cells 1) Canis lupus familiaris
Analyze
Symbol: TREM1
Name: triggering receptor expressed on myeloid cells 1
RGD ID: 12165478
Description: ENCODES a protein that exhibits receptor decoy activity (ortholog); INVOLVED IN cellular response to lipopolysaccharide (ortholog); cellular response to vitamin D (ortholog); neutrophil chemotaxis (ortholog); ASSOCIATED WITH Acute Lung Injury (ortholog); acute pancreatitis (ortholog); allergic asthma (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: TREM-1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1129,990,678 - 10,000,195 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl129,990,679 - 10,000,236 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1210,020,952 - 10,030,132 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01210,470,281 - 10,479,802 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1210,470,277 - 10,479,839 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11210,002,655 - 10,011,845 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01210,084,374 - 10,093,559 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01210,179,448 - 10,188,597 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21549750   PMID:30032202  


Genomics

Comparative Map Data
TREM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1129,990,678 - 10,000,195 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl129,990,679 - 10,000,236 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1210,020,952 - 10,030,132 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01210,470,281 - 10,479,802 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1210,470,277 - 10,479,839 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11210,002,655 - 10,011,845 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01210,084,374 - 10,093,559 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01210,179,448 - 10,188,597 (-)NCBIUU_Cfam_GSD_1.0
TREM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38641,267,385 - 41,286,682 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl641,267,100 - 41,286,682 (-)EnsemblGRCh38hg38GRCh38
GRCh37641,235,123 - 41,254,420 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36641,351,690 - 41,362,435 (-)NCBINCBI36Build 36hg18NCBI36
Build 34641,351,689 - 41,362,435NCBI
Celera642,797,142 - 42,807,885 (-)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef640,961,518 - 40,972,978 (-)NCBIHuRef
CHM1_1641,246,251 - 41,257,709 (-)NCBICHM1_1
T2T-CHM13v2.0641,096,688 - 41,115,965 (-)NCBIT2T-CHM13v2.0
Trem1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391748,539,763 - 48,553,955 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1748,539,796 - 48,553,952 (+)EnsemblGRCm39 Ensembl
GRCm381748,232,713 - 48,246,927 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1748,232,768 - 48,246,924 (+)EnsemblGRCm38mm10GRCm38
MGSCv371748,371,922 - 48,386,091 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361747,698,178 - 47,712,333 (+)NCBIMGSCv36mm8
Celera1751,668,001 - 51,682,161 (+)NCBICelera
Cytogenetic Map17CNCBI
cM Map1723.99NCBI
Trem1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8920,259,227 - 20,276,879 (-)NCBIGRCr8
mRatBN7.2912,763,819 - 12,779,285 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl912,763,819 - 12,779,203 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx921,277,179 - 21,288,238 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0926,343,405 - 26,354,464 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0924,732,622 - 24,743,689 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0914,727,887 - 14,743,371 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl914,727,976 - 14,809,447 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0913,649,246 - 13,664,645 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.498,175,081 - 8,186,142 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.198,175,083 - 8,193,441 (-)NCBI
Celera910,535,490 - 10,546,547 (-)NCBICelera
Cytogenetic Map9q12NCBI
TREM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2555,770,728 - 55,782,228 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1651,639,052 - 51,652,228 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0640,861,283 - 40,874,446 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1642,168,992 - 42,182,134 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl642,163,337 - 42,183,091 (-)Ensemblpanpan1.1panPan2
Trem1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494645,374,752 - 45,385,967 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647618,574,381 - 18,583,647 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647618,577,825 - 18,583,675 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TREM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl736,510,253 - 36,531,796 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1736,510,253 - 36,531,796 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2741,804,122 - 41,825,672 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TREM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11730,873,647 - 30,885,292 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1730,873,666 - 30,886,967 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604441,275,669 - 41,288,974 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in TREM1
78 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 21 22 16 6 6 6 6 32 21 10 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000002493   ⟹   ENSCAFP00000002313
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl129,990,679 - 10,000,236 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000084674   ⟹   ENSCAFP00000063632
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl129,990,679 - 9,997,950 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845027325   ⟹   ENSCAFP00845021506
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1210,470,277 - 10,479,839 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845027355   ⟹   ENSCAFP00845021532
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1210,470,277 - 10,477,539 (-)Ensembl
RefSeq Acc Id: NM_001284492   ⟹   NP_001271421
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1129,990,973 - 10,000,150 (-)NCBI
Dog10K_Boxer_Tasha1210,020,952 - 10,030,132 (-)NCBI
ROS_Cfam_1.01210,470,571 - 10,479,739 (-)NCBI
UMICH_Zoey_3.11210,002,655 - 10,011,845 (-)NCBI
UNSW_CanFamBas_1.01210,084,374 - 10,093,559 (-)NCBI
UU_Cfam_GSD_1.01210,179,448 - 10,188,597 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038682770   ⟹   XP_038538698
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01210,470,281 - 10,479,802 (-)NCBI
RefSeq Acc Id: NP_001271421   ⟸   NM_001284492
- Peptide Label: precursor
- UniProtKB: A0A8C0K5N1 (UniProtKB/TrEMBL),   A0A8C0MDA6 (UniProtKB/TrEMBL),   G0ZS87 (UniProtKB/TrEMBL),   A0A8C0MDB9 (UniProtKB/TrEMBL),   A0A8I3NKZ7 (UniProtKB/TrEMBL),   E2RP37 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000063632   ⟸   ENSCAFT00000084674
Ensembl Acc Id: ENSCAFP00000002313   ⟸   ENSCAFT00000002493
RefSeq Acc Id: XP_038538698   ⟸   XM_038682770
- Peptide Label: isoform X1
- UniProtKB: A0A8C0MDB9 (UniProtKB/TrEMBL),   A0A8I3NKZ7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845021506   ⟸   ENSCAFT00845027325
Ensembl Acc Id: ENSCAFP00845021532   ⟸   ENSCAFT00845027355
Protein Domains
Ig-like

Promoters
RGD ID:13685416
Promoter ID:EPDNEW_C3484
Type:single initiation site
Name:TREM1_1
Description:triggering receptor expressed on myeloid cells 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11210,000,180 - 10,000,240EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000001591 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030006207 UniProtKB/TrEMBL
  ENSCAFG00040004948 UniProtKB/TrEMBL
  ENSCAFG00845015313 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000002493.5 UniProtKB/TrEMBL
  ENSCAFT00000084674.2 UniProtKB/TrEMBL
  ENSCAFT00030011430.1 UniProtKB/TrEMBL
  ENSCAFT00030011468.1 UniProtKB/TrEMBL
  ENSCAFT00030011506.1 UniProtKB/TrEMBL
  ENSCAFT00040009304.1 UniProtKB/TrEMBL
  ENSCAFT00040009336.1 UniProtKB/TrEMBL
  ENSCAFT00845027325 ENTREZGENE
  ENSCAFT00845027325.1 UniProtKB/TrEMBL
  ENSCAFT00845027355 ENTREZGENE
  ENSCAFT00845027355.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
KEGG Report cfa:608994 UniProtKB/TrEMBL
NCBI Gene TREM1 ENTREZGENE
PANTHER PTHR19357:SF0 UniProtKB/TrEMBL
  TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1 UniProtKB/TrEMBL
Pfam V-set UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A8C0K5N1 ENTREZGENE
  A0A8C0MDA6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0MDB9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0MIS5_CANLF UniProtKB/TrEMBL
  A0A8I3NKZ7 ENTREZGENE, UniProtKB/TrEMBL
  E2RP37 ENTREZGENE, UniProtKB/TrEMBL
  G0ZS87 ENTREZGENE
UniProt Secondary G0ZS87 UniProtKB/TrEMBL
VGNC ID VGNC:47793 ENTREZGENE