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Gene: TREM1 (triggering receptor expressed on myeloid cells 1) Canis lupus familiaris

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Symbol:

TREM1

Name:

triggering receptor expressed on myeloid cells 1

RGD ID:

12165478

Description:

ENCODES a protein that exhibits receptor decoy activity (ortholog); INVOLVED IN cellular response to lipopolysaccharide (ortholog); cellular response to vitamin D (ortholog); neutrophil chemotaxis (ortholog); ASSOCIATED WITH Acute Lung Injury (ortholog); acute pancreatitis (ortholog); allergic asthma (ortholog); FOUND IN extracellular space (ortholog)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

TREM-1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	9,990,678 - 10,000,195 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	9,990,679 - 10,000,236 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	10,020,952 - 10,030,132 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	10,470,281 - 10,479,802 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	10,470,277 - 10,479,839 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	10,002,655 - 10,011,845 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	10,084,374 - 10,093,559 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	10,179,448 - 10,188,597 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TREM1	Dog	Acute Lung Injury	exacerbates	ISO	RGD:1309467	9068941		RGD	PMID:26832696\|REF_RGD_ID:127284840
TREM1	Dog	Acute Lung Injury	ameliorates	ISO	RGD:1309467	9068941		RGD	PMID:26832696\|REF_RGD_ID:127284840
TREM1	Dog	acute pancreatitis	severity	ISO	RGD:1319824	9068941		RGD	PMID:26250893\|REF_RGD_ID:11522077
TREM1	Dog	acute pancreatitis	ameliorates	ISO	RGD:1309467	9068941		RGD	PMID:19787284\|REF_RGD_ID:127284839
TREM1	Dog	allergic asthma		ISO	RGD:1319824	9068941		RGD	PMID:21592044\|REF_RGD_ID:126928124
TREM1	Dog	allergic asthma	exacerbates	ISO	RGD:1319824	9068941		RGD	PMID:21592044\|REF_RGD_ID:126928124
TREM1	Dog	amyloidosis		ISO	RGD:1319823	9068941	associated with familial Mediterranean fever;protein:increased expression:serum:	RGD	PMID:31474164\|REF_RGD_ID:127229901
TREM1	Dog	bacterial gastritis		ISO	RGD:1319823	9068941	mRNA,protein:increased expression:gastric epithelium	RGD	PMID:18321350\|REF_RGD_ID:126928123
TREM1	Dog	bacterial meningitis	disease_progression	ISO	RGD:1319823	9068941		RGD	PMID:16786330\|REF_RGD_ID:126928126
TREM1	Dog	bacterial pneumonia	severity	ISO	RGD:1319823	9068941		RGD	PMID:22996209\|PMID:24465168\|REF_RGD_ID:126848796\|REF_RGD_ID:126925987
TREM1	Dog	bacterial pneumonia	ameliorates	ISO	RGD:1309467	9068941		RGD	PMID:16960786\|REF_RGD_ID:127229902
TREM1	Dog	bacterial sepsis	treatment	ISO	RGD:1319823	9068941		RGD	PMID:21507332\|REF_RGD_ID:126925982
TREM1	Dog	bacterial sepsis	ameliorates	ISO	RGD:1309467	9068941	associated with bacterial pneumonia	RGD	PMID:16960786\|REF_RGD_ID:127229902
TREM1	Dog	bacterial sepsis	exacerbates	ISO	RGD:1319824	9068941		RGD	PMID:17230441\|REF_RGD_ID:126928125
TREM1	Dog	chorioamnionitis		ISO	RGD:1319823	9068941	associated with Premature Obstetric Labor;protein:increased expression:amniotic fluid:	RGD	PMID:19591072\|REF_RGD_ID:127229904
TREM1	Dog	colitis	severity	ISO	RGD:1319824	9068941		RGD	PMID:24453980\|REF_RGD_ID:126925972
TREM1	Dog	congestive heart failure	treatment	ISO	RGD:1309467	9068941		RGD	PMID:33495812\|REF_RGD_ID:127229929
TREM1	Dog	depressive disorder	treatment	ISO	RGD:1309467	9068941		RGD	PMID:32009956\|REF_RGD_ID:127284856
TREM1	Dog	Diabetic Nephropathies		ISO	RGD:1319823	9068941	protein:increased expression:kidney interstitium	RGD	PMID:30478987\|REF_RGD_ID:127229931
TREM1	Dog	Diabetic Nephropathies	treatment	ISO	RGD:1309467	9068941		RGD	PMID:29331667\|PMID:30478987\|REF_RGD_ID:127229931\|REF_RGD_ID:127284861
TREM1	Dog	endometritis	ameliorates	ISO	RGD:1319824	9068941		RGD	PMID:31365951\|REF_RGD_ID:126928127
TREM1	Dog	Endotoxemia		ISO	RGD:1319823	9068941		RGD	PMID:15585833\|REF_RGD_ID:126928122
TREM1	Dog	Endotoxemia	treatment	ISO	RGD:1319824	9068941		RGD	PMID:21507332\|REF_RGD_ID:126925982
TREM1	Dog	Experimental Autoimmune Neuritis		ISO	RGD:1309467	9068941	mRNA:increased expression:sciatic nerve,peripheral blood mononuclar cell	RGD	PMID:28260057\|REF_RGD_ID:127284841
TREM1	Dog	Experimental Autoimmune Neuritis	ameliorates	ISO	RGD:1309467	9068941		RGD	PMID:28260057\|REF_RGD_ID:127284841
TREM1	Dog	Fungal Keratitis		ISO	RGD:1319824	9068941	mRNA:increased expression:cornea	RGD	PMID:26963514\|REF_RGD_ID:11526921
TREM1	Dog	Fungal Keratitis	treatment	ISO	RGD:1319824	9068941		RGD	PMID:26963514\|REF_RGD_ID:11526921
TREM1	Dog	Fungal Keratitis		ISO	RGD:1319823	9068941	mRNA:increased expression:cornea	RGD	PMID:26963514\|REF_RGD_ID:11526921
TREM1	Dog	Hemorrhagic Shock	ameliorates	ISO	RGD:1309467	9068941		RGD	PMID:19333144\|REF_RGD_ID:127284838
TREM1	Dog	hepatitis B		ISO	RGD:1319823	9068941	protein:increased expression:plasma	RGD	PMID:27328755\|REF_RGD_ID:126925974
TREM1	Dog	hepatitis C		ISO	RGD:1319823	9068941	protein:increased expression:plasma	RGD	PMID:27328755\|REF_RGD_ID:126925974
TREM1	Dog	human immunodeficiency virus infectious disease		ISO	RGD:1319823	9068941	mRNA,protein:increased expression:peripheral blood mononuclear cell, macrophage, plasma	RGD	PMID:31260499\|REF_RGD_ID:126925971
TREM1	Dog	Intestinal Reperfusion Injury	ameliorates	ISO	RGD:1309467	9068941	associated with mesenteric vascular occlusion;	RGD	PMID:18091551\|REF_RGD_ID:127284848
TREM1	Dog	Klebsiella pneumonia	disease_progression	ISO	RGD:1319824	9068941		RGD	PMID:24396044\|REF_RGD_ID:126925976
TREM1	Dog	leishmaniasis	severity	ISO	RGD:1319824	9068941		RGD	PMID:24453980\|REF_RGD_ID:126925972
TREM1	Dog	Liver Abscess	severity	ISO	RGD:1319824	9068941	associated with Klebsiella pneumonia	RGD	PMID:24396044\|REF_RGD_ID:126925976
TREM1	Dog	malaria	severity	ISO	RGD:1319823	9068941	DNA:SNP: :rs2234237A>T (human)	RGD	PMID:27671831\|REF_RGD_ID:126848795
TREM1	Dog	melioidosis	severity	ISO	RGD:1319823	9068941		RGD	PMID:18008257\|REF_RGD_ID:126928120
TREM1	Dog	melioidosis	treatment	ISO	RGD:1319824	9068941		RGD	PMID:18008257\|REF_RGD_ID:126928120
TREM1	Dog	melioidosis		ISO	RGD:1319824	9068941		RGD	PMID:18008257\|REF_RGD_ID:126928120
TREM1	Dog	mesenteric vascular occlusion	ameliorates	ISO	RGD:1309467	9068941		RGD	PMID:18091551\|REF_RGD_ID:127284848
TREM1	Dog	middle cerebral artery infarction	ameliorates	ISO	RGD:1309467	9068941		RGD	PMID:32736673\|REF_RGD_ID:127284860
TREM1	Dog	myocardial infarction	ameliorates	ISO	RGD:1319824	9068941		RGD	PMID:25840803\|REF_RGD_ID:127284842
TREM1	Dog	myocardial infarction	ameliorates	ISO	RGD:1309467	9068941		RGD	PMID:25840803\|REF_RGD_ID:127284842
TREM1	Dog	myocardial infarction	disease_progression	ISO	RGD:1319823	9068941		RGD	PMID:25840803\|REF_RGD_ID:127284842
TREM1	Dog	periodontitis		ISO	RGD:1309467	9068941	mRNA,protein:increased expression:periodontium	RGD	PMID:29972971\|REF_RGD_ID:127284858
TREM1	Dog	pleural empyema	treatment	ISO	RGD:1309467	9068941		RGD	PMID:20819512\|REF_RGD_ID:127284851
TREM1	Dog	Pneumococcal Pneumonia	ameliorates	ISO	RGD:1319824	9068941		RGD	PMID:19596984\|REF_RGD_ID:127229903
TREM1	Dog	Pneumococcal Pneumonia		ISO	RGD:1319824	9068941		RGD	PMID:24752755\|REF_RGD_ID:126928121
TREM1	Dog	pulmonary tuberculosis	disease_progression	ISO	RGD:1319823	9068941		RGD	PMID:29844416\|REF_RGD_ID:126925977
TREM1	Dog	rheumatoid arthritis	treatment	ISO	RGD:1309467	9068941		RGD	PMID:27049384\|REF_RGD_ID:127229930
TREM1	Dog	Rotator Cuff Injuries		ISO	RGD:1309467	9068941	protein:increased expression:tendon:	RGD	PMID:29891998\|REF_RGD_ID:127284862
TREM1	Dog	Schistosomiasis Mansoni		ISO	RGD:1319824	9068941		RGD	PMID:21332515\|REF_RGD_ID:126925988
TREM1	Dog	Sepsis		ISO	RGD:1319823	9068941	mRNA:decreased expression:polymorph nuclear cell:	RGD	PMID:22996209\|REF_RGD_ID:126925987
TREM1	Dog	Sepsis	treatment	ISO	RGD:1309467	9068941		RGD	PMID:22147417\|REF_RGD_ID:127284847
TREM1	Dog	Sepsis	disease_progression	ISO	RGD:1319823	9068941		RGD	PMID:22809118\|REF_RGD_ID:126925981
TREM1	Dog	Subarachnoid Hemorrhage	severity	ISO	RGD:1319823	9068941		RGD	PMID:33727099\|REF_RGD_ID:127284864
TREM1	Dog	Subarachnoid Hemorrhage	treatment	ISO	RGD:1309467	9068941		RGD	PMID:30910643\|REF_RGD_ID:127284863
TREM1	Dog	swine influenza	severity	ISO	RGD:1319824	9068941		RGD	PMID:24453980\|REF_RGD_ID:126925972
TREM1	Dog	Toxemia	ameliorates	ISO	RGD:1319824	9068941		RGD	PMID:17230441\|REF_RGD_ID:126928125
TREM1	Dog	toxic shock syndrome		ISO	RGD:1319823	9068941	mRNA:decreased expression:polymorphonuclear leukocyte	RGD	PMID:24465168\|REF_RGD_ID:126848796
TREM1	Dog	viral hepatitis	disease_progression	ISO	RGD:1319824	9068941		RGD	PMID:27328755\|REF_RGD_ID:126925974

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TREM1	Dog	infantile Refsum disease		ISO	RGD:1319823	8554872	ClinVar Annotator: match by term: ADRENOLEUKODYSTROPHY, AUTOSOMAL NEONATAL	ClinVar	PMID:19877282\|PMID:21031596\|PMID:28492532\|PMID:8670792
TREM1	Dog	Zellweger syndrome		ISO	RGD:1319823	8554872	ClinVar Annotator: match by term: Peroxisome biogenesis disorders, Zellweger syndrome spectrum	ClinVar	PMID:19877282\|PMID:21031596\|PMID:28492532\|PMID:8670792

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TREM1	Dog	liver disease		ISO	RGD:1319823	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:12651611

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TREM1	Dog	adaptive immune response	involved_in	IEA	UniProtKB-KW:KW-1064	150520179		UniProt	GO_REF:0000043
TREM1	Dog	cellular response to lipopolysaccharide		ISO	RGD:1309467	9068941		RGD	PMID:26383906\|REF_RGD_ID:127284850
TREM1	Dog	cellular response to vitamin D		ISO	RGD:1309467	9068941		RGD	PMID:29331667\|REF_RGD_ID:127284861
TREM1	Dog	immune response	involved_in	IBA	MGI:1930003\|MGI:1930005\|PANTHER:PTN000451705	150520179		GO_Central	GO_REF:0000033
TREM1	Dog	immune system process	involved_in	IEA	UniProtKB-KW:KW-0391	150520179		UniProt	GO_REF:0000043
TREM1	Dog	innate immune response	involved_in	IEA	UniProtKB-KW:KW-0399	150520179		UniProt	GO_REF:0000043
TREM1	Dog	neutrophil chemotaxis	involved_in	IBA	MGI:1930003\|MGI:1930005\|PANTHER:PTN000451705	150520179		GO_Central	GO_REF:0000033
TREM1	Dog	neutrophil chemotaxis	acts_upstream_of_or_within	ISO	MGI:1930003	9068941	PMID:23241959	MGI	PMID:23241959
TREM1	Dog	neutrophil extravasation	acts_upstream_of_or_within	ISO	MGI:1930003	9068941	PMID:23241959	MGI	PMID:23241959
TREM1	Dog	neutrophil migration	acts_upstream_of_or_within	ISO	MGI:1930003	9068941	PMID:23241959	MGI	PMID:23241959
TREM1	Dog	neutrophil-mediated killing of gram-negative bacterium	acts_upstream_of_or_within	ISO	MGI:1930003	9068941	PMID:23241959	MGI	PMID:23241959
TREM1	Dog	neutrophil-mediated killing of gram-negative bacterium	involved_in	IBA	MGI:1930003\|MGI:1930005\|PANTHER:PTN000451705	150520179		GO_Central	GO_REF:0000033
TREM1	Dog	positive regulation of cardiac muscle cell apoptotic process		ISO	RGD:1309467	9068941		RGD	PMID:33495812\|REF_RGD_ID:127229929
TREM1	Dog	positive regulation of cell-matrix adhesion		ISO	RGD:1309467	9068941		RGD	PMID:29331667\|REF_RGD_ID:127284861
TREM1	Dog	positive regulation of macrophage chemotaxis		ISO	RGD:1309467	9068941		RGD	PMID:29331667\|REF_RGD_ID:127284861

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TREM1	Dog	cell surface	is_active_in	IBA	PANTHER:PTN000451705\|UniProtKB:Q9NP99	150520179		GO_Central	GO_REF:0000033
TREM1	Dog	cell surface	is_active_in	IEA	UniProtKB:Q9NP99\|ensembl:ENSP00000244709	150520179		Ensembl	GO_REF:0000107
TREM1	Dog	extracellular space	is_active_in	ISO	RGD:1319823	9068941	PMID:26561551	UniProt	PMID:26561551
TREM1	Dog	membrane	located_in	IEA	UniProtKB-KW:KW-0472	150520179		UniProt	GO_REF:0000043
TREM1	Dog	plasma membrane	located_in	IEA	UniProtKB-KW:KW-1003	150520179		UniProt	GO_REF:0000043
TREM1	Dog	plasma membrane	located_in	IEA	UniProtKB-SubCell:SL-0039	150520179		UniProt	GO_REF:0000044

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TREM1	Dog	receptor decoy activity	enables	ISO	RGD:1319823	9068941	PMID:26561551	UniProt	PMID:26561551
TREM1	Dog	scaffold protein binding	enables	IEA	UniProtKB:Q9NP99\|ensembl:ENSP00000244709	150520179		Ensembl	GO_REF:0000107
TREM1	Dog	transmembrane signaling receptor activity	enables	IBA	PANTHER:PTN000451705\|UniProtKB:Q9NP99	150520179		GO_Central	GO_REF:0000033
TREM1	Dog	transmembrane signaling receptor activity	enables	IEA	UniProtKB:Q9NP99\|ensembl:ENSP00000244709	150520179		Ensembl	GO_REF:0000107

PMID:21549750	PMID:30032202

TREM1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	9,990,678 - 10,000,195 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	9,990,679 - 10,000,236 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	10,020,952 - 10,030,132 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	10,470,281 - 10,479,802 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	10,470,277 - 10,479,839 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	10,002,655 - 10,011,845 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	10,084,374 - 10,093,559 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	10,179,448 - 10,188,597 (-)	NCBI		UU_Cfam_GSD_1.0

TREM1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	41,267,385 - 41,286,682 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	41,267,100 - 41,286,682 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	41,235,123 - 41,254,420 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	41,351,690 - 41,362,435 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	41,351,689 - 41,362,435	NCBI
Celera	6	42,797,142 - 42,807,885 (-)	NCBI		Celera
Cytogenetic Map	6	p21.1	NCBI
HuRef	6	40,961,518 - 40,972,978 (-)	NCBI		HuRef
CHM1_1	6	41,246,251 - 41,257,709 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	41,096,688 - 41,115,965 (-)	NCBI		T2T-CHM13v2.0

Trem1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	48,539,763 - 48,553,955 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	48,539,796 - 48,553,952 (+)	Ensembl		GRCm39 Ensembl
GRCm38	17	48,232,713 - 48,246,927 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	48,232,768 - 48,246,924 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	48,371,922 - 48,386,091 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	47,698,178 - 47,712,333 (+)	NCBI		MGSCv36	mm8
Celera	17	51,668,001 - 51,682,161 (+)	NCBI		Celera
Cytogenetic Map	17	C	NCBI
cM Map	17	23.99	NCBI

Trem1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	20,259,227 - 20,276,879 (-)	NCBI		GRCr8
mRatBN7.2	9	12,763,819 - 12,779,285 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	12,763,819 - 12,779,203 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	21,277,179 - 21,288,238 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	26,343,405 - 26,354,464 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	24,732,622 - 24,743,689 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	14,727,887 - 14,743,371 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	14,727,976 - 14,809,447 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	13,649,246 - 13,664,645 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	8,175,081 - 8,186,142 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	8,175,083 - 8,193,441 (-)	NCBI
Celera	9	10,535,490 - 10,546,547 (-)	NCBI		Celera
Cytogenetic Map	9	q12	NCBI

TREM1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	55,770,728 - 55,782,228 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	51,639,052 - 51,652,228 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	40,861,283 - 40,874,446 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	42,168,992 - 42,182,134 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	42,163,337 - 42,183,091 (-)	Ensembl	panpan1.1		panPan2

Trem1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	45,374,752 - 45,385,967 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936476	18,574,381 - 18,583,647 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936476	18,577,825 - 18,583,675 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TREM1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	36,510,253 - 36,531,796 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	36,510,253 - 36,531,796 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	41,804,122 - 41,825,672 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TREM1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	30,873,647 - 30,885,292 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	30,873,666 - 30,886,967 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	41,275,669 - 41,288,974 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants in TREM1
78 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	21	22	16	6	6	6	6	32	21	10	14	10


RefSeq Transcripts	NM_001284492	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005627314	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038682770	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000123	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000357	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JF330417	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000002493 ⟹ ENSCAFP00000002313

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	12	9,990,679 - 10,000,236 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00000084674 ⟹ ENSCAFP00000063632

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	12	9,990,679 - 9,997,950 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845027325 ⟹ ENSCAFP00845021506

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	12	10,470,277 - 10,479,839 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845027355 ⟹ ENSCAFP00845021532

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	12	10,470,277 - 10,477,539 (-)	Ensembl

RefSeq Acc Id:

NM_001284492 ⟹ NP_001271421

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	12	9,990,973 - 10,000,150 (-)	NCBI
Dog10K_Boxer_Tasha	12	10,020,952 - 10,030,132 (-)	NCBI
ROS_Cfam_1.0	12	10,470,571 - 10,479,739 (-)	NCBI
UMICH_Zoey_3.1	12	10,002,655 - 10,011,845 (-)	NCBI
UNSW_CanFamBas_1.0	12	10,084,374 - 10,093,559 (-)	NCBI
UU_Cfam_GSD_1.0	12	10,179,448 - 10,188,597 (-)	NCBI

Sequence:

show sequence

ATGAGGAAGGCCAGGCTCTGGGAGCTGCTCTGGTTGCTCTTCATCTCAGAACTCCAAGCTACAACTGAACCAGATGAAATAAAGTATGTCTTAGCAGAGGGAGGCACCCTGAATATGAAATGTACCAC
CTCCACCTGGAAGTACACCTATAGCCAGAAAGCTTGGCAGAAGCTTATGGATAGAGAGAAGCCCCTGACACTGATTTTCACAGAGAATGTTTCAGGGGATACCAGTCAAGTCCAGAGAGGCAGGTACT
TCCTAGAAGACATCCCCAGCGAGGCCATCCTGAACGTCCAAATGACTAATCTTCAAGTGGAGGATTCAGGACTGTATCAGTGTGTGATCTACCACCCTCAGAAGAACCCTGACATCCTGTACCCCCGT
GTCCGCCTGGTGGTGACCAAGGGCATCACTGCATCAGACAAGAGTCCTACCCAGAACTTGGCTCAGATTTCCACCCATCCTCCTACCACTACCAAGGCCCAGAGCACGCTTCTTGCCAGCCCCAGGAC
TGTGACCCAACTCCCACCCAAATCAACTGCTGACACCTCCTCTCCTGACTTTGGAGTCAACATCACAAATGTGACGAATGTCACCAGCTATGGTTTCAGGTTCTCTGTGATCAACATTGTCATTCTTG
TGCTGTGTGGATTCCTGAGCAAGAGCCTGGTCTTCACTGTCCTGATTGCTGTCACACAGAGGTCATTTGGACCCTAG

hide sequence

RefSeq Acc Id:

XM_038682770 ⟹ XP_038538698

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	12	10,470,281 - 10,479,802 (-)	NCBI


Protein RefSeqs	NP_001271421	(Get FASTA)	NCBI Sequence Viewer
	XP_038538698	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AEB77686	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000002313.3
	ENSCAFP00000063632.1
	ENSCAFP00030009998.1
	ENSCAFP00030010032.1
	ENSCAFP00030010067.1
	ENSCAFP00040008063.1
	ENSCAFP00040008086.1
	ENSCAFP00845021506
	ENSCAFP00845021506.1
	ENSCAFP00845021532
	ENSCAFP00845021532.1

RefSeq Acc Id:	NP_001271421 ⟸ NM_001284492
- Peptide Label:	precursor
- UniProtKB:	E2RP37 (UniProtKB/TrEMBL), A0A8C0K5N1 (UniProtKB/TrEMBL), A0A8C0MDA6 (UniProtKB/TrEMBL), G0ZS87 (UniProtKB/TrEMBL), A0A8C0MDB9 (UniProtKB/TrEMBL), A0A8I3NKZ7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRKARLWELLWLLFISELQATTEPDEIKYVLAEGGTLNMKCTTSTWKYTYSQKAWQKLMDREKPLTLIFTENVSGDTSQVQRGRYFLEDIPSEAILNVQMTNLQVEDSGLYQCVIYHPQKNPDILYPR VRLVVTKGITASDKSPTQNLAQISTHPPTTTKAQSTLLASPRTVTQLPPKSTADTSSPDFGVNITNVTNVTSYGFRFSVINIVILVLCGFLSKSLVFTVLIAVTQRSFGP hide sequence

Ensembl Acc Id:

ENSCAFP00000063632 ⟸ ENSCAFT00000084674

Ensembl Acc Id:

ENSCAFP00000002313 ⟸ ENSCAFT00000002493

RefSeq Acc Id:	XP_038538698 ⟸ XM_038682770
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0MDB9 (UniProtKB/TrEMBL), A0A8I3NKZ7 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845021506 ⟸ ENSCAFT00845027325

Protein Domains

Ig-like

RGD ID:

13685416

Promoter ID:

EPDNEW_C3484

Type:

single initiation site

Name:

TREM1_1

Description:

triggering receptor expressed on myeloid cells 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	12	10,000,180 - 10,000,240	EPDNEW

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000001591	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030006207	UniProtKB/TrEMBL
	ENSCAFG00040004948	UniProtKB/TrEMBL
	ENSCAFG00845015313	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000002493.5	UniProtKB/TrEMBL
	ENSCAFT00000084674.2	UniProtKB/TrEMBL
	ENSCAFT00030011430.1	UniProtKB/TrEMBL
	ENSCAFT00030011468.1	UniProtKB/TrEMBL
	ENSCAFT00030011506.1	UniProtKB/TrEMBL
	ENSCAFT00040009304.1	UniProtKB/TrEMBL
	ENSCAFT00040009336.1	UniProtKB/TrEMBL
	ENSCAFT00845027325	ENTREZGENE
	ENSCAFT00845027325.1	UniProtKB/TrEMBL
	ENSCAFT00845027355	ENTREZGENE
	ENSCAFT00845027355.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
InterPro	Ig-like_dom	UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
	Ig_sub	UniProtKB/TrEMBL
	Ig_V-set	UniProtKB/TrEMBL
KEGG Report	cfa:608994	UniProtKB/TrEMBL
NCBI Gene	TREM1	ENTREZGENE
PANTHER	PTHR19357:SF0	UniProtKB/TrEMBL
	TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1	UniProtKB/TrEMBL
Pfam	V-set	UniProtKB/TrEMBL
PROSITE	IG_LIKE	UniProtKB/TrEMBL
SMART	SM00409	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48726	UniProtKB/TrEMBL
UniProt	A0A8C0K5N1	ENTREZGENE
	A0A8C0MDA6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0MDB9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0MIS5_CANLF	UniProtKB/TrEMBL
	A0A8I3NKZ7	ENTREZGENE, UniProtKB/TrEMBL
	E2RP37	ENTREZGENE, UniProtKB/TrEMBL
	G0ZS87	ENTREZGENE
UniProt Secondary	G0ZS87	UniProtKB/TrEMBL
VGNC ID	VGNC:47793	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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