PTEN (phosphatase and tensin homolog) - Rat Genome Database

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Gene: PTEN (phosphatase and tensin homolog) Chlorocebus sabaeus
Analyze
Symbol: PTEN
Name: phosphatase and tensin homolog
RGD ID: 18778066
Description: ENCODES a protein that exhibits ionotropic glutamate receptor binding (ortholog); molecular function inhibitor activity (ortholog); PDZ domain binding (ortholog); INVOLVED IN adult behavior (ortholog); angiogenesis (ortholog); apoptotic process (ortholog); PARTICIPATES IN altered phosphatidylinositol 3-kinase signaling pathway; altered phosphatidylinositol 3-kinase-Akt signaling pathway; endometrial cancer pathway; ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); acute megakaryocytic leukemia (ortholog); acute myocardial infarction (ortholog); FOUND IN dendritic spine (ortholog); myelin sheath adaxonal region (ortholog); neuron projection (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1981,308,058 - 81,412,386 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl981,309,099 - 81,409,146 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604841,972,612 - 42,077,014 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute lymphoblastic leukemia  (ISO)
acute megakaryocytic leukemia  (ISO)
acute myocardial infarction  (ISO)
adenocarcinoma  (ISO)
adenoid cystic carcinoma  (ISO)
angiomyolipoma  (ISO)
anisometropia  (ISO)
asthma  (ISO)
Ataxia  (ISO)
autism spectrum disorder  (ISO)
autistic disorder  (ISO)
bacterial pneumonia  (ISO)
Bannayan-Riley-Ruvalcaba syndrome  (ISO)
biliary atresia  (ISO)
bladder squamous cell carcinoma  (ISO)
brain disease  (ISO)
Brain Neoplasms  (ISO)
breast cancer  (ISO)
Breast Cancer, Familial  (ISO)
breast carcinoma  (ISO)
Breast Neoplasms  (ISO)
carcinoma  (ISO)
Cardiomegaly  (ISO)
Cardiovascular Abnormalities  (ISO)
cataract  (ISO)
cerebral cavernous malformation  (ISO)
cervix uteri carcinoma in situ  (ISO)
Chlamydiaceae Infections  (ISO)
cholangiocarcinoma  (ISO)
colon cancer  (ISO)
colon carcinoma  (ISO)
colorectal cancer  (ISO)
Colorectal Neoplasms  (ISO)
Congenital Hypomyelinating Neuropathy  (ISO)
Cowden syndrome  (ISO)
Cowden syndrome 4  (ISO)
Craniofacial Abnormalities  (ISO)
developmental coordination disorder  (ISO)
Developmental Disabilities  (ISO)
diabetes mellitus  (ISO)
Diabetic Nephropathies  (ISO)
diabetic retinopathy  (ISO)
diffuse large B-cell lymphoma  (ISO)
disease of cellular proliferation  (ISO)
Disease Progression  (ISO)
Ductal Carcinoma  (ISO)
dysplastic nevus syndrome  (ISO)
endometrial adenocarcinoma  (ISO)
endometrial cancer  (ISO)
endometrial carcinoma  (ISO)
endometrial hyperplasia  (ISO)
Endometrial Intraepithelial Neoplasia  (ISO)
Endometrial Neoplasms  (ISO)
Endometrioid Carcinomas  (ISO)
epilepsy  (ISO)
Epstein-Barr virus infectious disease  (ISO)
esophageal cancer  (ISO)
Experimental Mammary Neoplasms  (ISO)
Experimental Melanoma  (ISO)
familial melanoma  (ISO)
familial meningioma  (ISO)
fetal alcohol spectrum disorder  (ISO)
Follicular Thyroid Cancer  (ISO)
follicular thyroid carcinoma  (ISO)
gastric adenocarcinoma  (ISO)
Generalized Epilepsy  (ISO)
genetic disease  (ISO)
glioblastoma  (ISO)
head and neck squamous cell carcinoma  (ISO)
Helicobacter Infections  (ISO)
hemangioma  (ISO)
hemangiopericytoma  (ISO)
Hemimegalencephaly  (ISO)
hepatitis B  (ISO)
hepatocellular adenoma  (ISO)
hepatocellular carcinoma  (ISO)
Hepatomegaly  (ISO)
hereditary breast ovarian cancer syndrome  (ISO)
Hereditary Neoplastic Syndromes  (ISO)
high grade glioma  (ISO)
hyperinsulinism  (ISO)
hypertension  (ISO)
Hypertrophy  (ISO)
in situ carcinoma  (ISO)
Insulin Resistance  (ISO)
intellectual disability  (ISO)
intermediate coronary syndrome  (ISO)
intestinal pseudo-obstruction  (ISO)
Intimal Hyperplasia  (ISO)
intrahepatic cholangiocarcinoma  (ISO)
juvenile polyposis syndrome  (ISO)
Language Development Disorders  (ISO)
Left Ventricular Hypertrophy  (ISO)
leiomyoma  (ISO)
leukemia  (ISO)
lipoma  (ISO)
lipomatosis  (ISO)
liver cirrhosis  (ISO)
long QT syndrome  (ISO)
lung adenocarcinoma  (ISO)
Lung Neoplasms  (ISO)
lung non-small cell carcinoma  (ISO)
lung oat cell carcinoma  (ISO)
lung small cell carcinoma  (ISO)
lung squamous cell carcinoma  (ISO)
Lymphatic Metastasis  (ISO)
lymphoma  (ISO)
Macrocephaly  (ISO)
macrocephaly-autism syndrome  (ISO)
major depressive disorder  (ISO)
melanoma  (ISO)
meningioma  (ISO)
metabolic dysfunction-associated steatotic liver disease  (ISO)
Mouth Neoplasms  (ISO)
Multiple Abnormalities  (ISO)
muscular dystrophy  (ISO)
myeloproliferative neoplasm  (ISO)
Myocardial Reperfusion Injury  (ISO)
Neoplasm Invasiveness  (ISO)
Neoplasm Metastasis  (ISO)
Neoplastic Cell Transformation  (ISO)
Nerve Sheath Neoplasms  (ISO)
Nervous System Malformations  (ISO)
Neurodevelopmental Disorders  (ISO)
Noonan syndrome with multiple lentigines  (ISO)
oral squamous cell carcinoma  (ISO)
osteochondrodysplasia  (ISO)
ovarian cancer  (ISO)
Ovarian Neoplasms  (ISO)
ovarian serous carcinoma  (ISO)
pancreatic cancer  (ISO)
papillary tumor of the pineal region  (ISO)
papillomavirus infectious disease  (ISO)
peripheral nervous system neoplasm  (ISO)
persistent fetal circulation syndrome  (ISO)
Pneumococcal Pneumonia  (ISO)
polydactyly  (ISO)
portal hypertension  (ISO)
prostate adenocarcinoma  (ISO)
prostate cancer  (ISO)
Prostate Cancer, Hereditary, 1  (ISO)
Prostate Cancer, Somatic  (ISO)
prostate carcinoma in situ  (ISO)
prostatic hypertrophy  (ISO)
Prostatic Neoplasms  (ISO)
Proteus syndrome  (ISO)
Pseudomonas Infections  (ISO)
PTEN hamartoma tumor syndrome  (ISO)
renal cell carcinoma  (ISO)
Renal Cell Carcinoma 1  (ISO)
Reperfusion Injury  (ISO)
retinitis pigmentosa  (ISO)
rhabdomyosarcoma  (ISO)
schizophrenia  (ISO)
Septic Peritonitis  (ISO)
Sezary's disease  (ISO)
silicosis  (ISO)
skin disease  (ISO)
skin melanoma  (ISO)
Skin Neoplasms  (ISO)
skin squamous cell carcinoma  (ISO)
Spinal Cord Injuries  (ISO)
sporadic breast cancer  (ISO)
squamous cell carcinoma  (ISO)
steatotic liver disease  (ISO)
stomach cancer  (ISO)
stomach disease  (ISO)
substance-related disorder  (ISO)
Thyroid Neoplasms  (ISO)
transient cerebral ischemia  (ISO)
transitional cell carcinoma  (ISO)
urinary bladder cancer  (ISO)
uterine cancer  (ISO)
uterine carcinosarcoma  (ISO)
Uterine Cervical Neoplasms  (ISO)
uterine corpus cancer  (ISO)
visual epilepsy  (ISO)
X-linked VACTERL association  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adult behavior  (ISO)
angiogenesis  (ISO)
apoptotic process  (IEA,ISO)
B cell proliferation  (ISO)
brain morphogenesis  (ISO)
canonical Wnt signaling pathway  (IEA)
cardiac muscle tissue development  (ISO)
cell migration  (ISO)
cell motility  (IEA)
cell population proliferation  (ISO)
cellular response to decreased oxygen levels  (ISO)
cellular response to electrical stimulus  (IEA)
cellular response to ethanol  (ISO)
cellular response to hypoxia  (ISO)
cellular response to insulin stimulus  (ISO)
cellular response to insulin-like growth factor stimulus  (ISO)
cellular response to leptin stimulus  (ISO)
cellular response to nerve growth factor stimulus  (ISO)
cellular response to sorbitol  (ISO)
central nervous system development  (ISO)
central nervous system myelin maintenance  (ISO)
central nervous system neuron axonogenesis  (ISO)
chromatin remodeling  (IEA)
dendritic spine morphogenesis  (ISO)
dentate gyrus development  (ISO)
endothelial cell migration  (ISO)
forebrain morphogenesis  (ISO)
gene expression  (ISO)
heart development  (ISO)
inositol phosphate catabolic process  (ISO)
learning or memory  (ISO)
lipid metabolic process  (IEA)
locomotor rhythm  (ISO)
locomotory behavior  (ISO)
long-term synaptic depression  (ISO)
long-term synaptic potentiation  (ISO)
male mating behavior  (ISO)
maternal behavior  (ISO)
memory  (ISO)
multicellular organismal response to stress  (ISO)
myelination  (ISO)
negative regulation of androgen receptor signaling pathway  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of axon regeneration  (ISO)
negative regulation of axonogenesis  (ISO)
negative regulation of B cell proliferation  (ISO)
negative regulation of cardiac muscle cell proliferation  (ISO)
negative regulation of cell cycle  (ISO)
negative regulation of cell cycle G1/S phase transition  (IEA)
negative regulation of cell migration  (IEA)
negative regulation of cell population proliferation  (IEA,ISO)
negative regulation of cell size  (ISO)
negative regulation of cellular senescence  (ISO)
negative regulation of cyclin-dependent protein serine/threonine kinase activity  (ISO)
negative regulation of defense response to bacterium  (ISO)
negative regulation of dendrite extension  (ISO)
negative regulation of dendritic spine morphogenesis  (ISO)
negative regulation of epithelial cell proliferation  (ISO)
negative regulation of epithelial to mesenchymal transition  (IEA)
negative regulation of excitatory postsynaptic potential  (ISO)
negative regulation of focal adhesion assembly  (IEA)
negative regulation of G1/S transition of mitotic cell cycle  (IEA)
negative regulation of keratinocyte migration  (IEA)
negative regulation of myelination  (ISO)
negative regulation of neuron projection development  (ISO)
negative regulation of organ growth  (ISO)
negative regulation of osteoblast differentiation  (IEA)
negative regulation of peptidyl-serine phosphorylation  (ISO)
negative regulation of phagocytosis  (ISO)
negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IEA,ISO)
negative regulation of potassium ion transmembrane transporter activity  (ISO)
negative regulation of protein kinase activity by regulation of protein phosphorylation  (ISO)
negative regulation of protein phosphorylation  (ISO)
negative regulation of ribosome biogenesis  (ISO)
negative regulation of signaling receptor activity  (ISO)
negative regulation of synaptic vesicle clustering  (ISO)
negative regulation of T cell proliferation  (ISO)
negative regulation of TORC1 signaling  (ISO)
negative regulation of vascular associated smooth muscle cell proliferation  (IEA)
negative regulation of wound healing, spreading of epidermal cells  (IEA)
nervous system development  (IEA)
neuron projection development  (ISO)
neuron-neuron synaptic transmission  (ISO)
phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IEA,ISO)
phosphatidylinositol dephosphorylation  (IEA,ISO)
platelet-derived growth factor receptor signaling pathway  (ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of apoptotic signaling pathway  (ISO)
positive regulation of cardiac muscle cell apoptotic process  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of DNA-binding transcription factor activity  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of excitatory postsynaptic potential  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of interleukin-6 production  (ISO)
positive regulation of neuron differentiation  (ISO)
positive regulation of tumor necrosis factor production  (ISO)
positive regulation of ubiquitin protein ligase activity  (ISO)
positive regulation of ubiquitin-dependent protein catabolic process  (IEA)
postsynaptic density assembly  (ISO)
prepulse inhibition  (ISO)
presynaptic membrane assembly  (ISO)
prostate gland growth  (ISO)
protein dephosphorylation  (ISO)
protein stabilization  (IEA)
regulation of axon regeneration  (ISO)
regulation of B cell apoptotic process  (ISO)
regulation of cell cycle  (ISO)
regulation of cellular component size  (ISO)
regulation of cellular localization  (ISO)
regulation of Fc receptor mediated stimulatory signaling pathway  (ISO)
regulation of macrophage apoptotic process  (ISO)
regulation of neuron projection development  (ISO)
regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IEA)
regulation of protein stability  (IEA)
regulation of synaptic transmission, GABAergic  (ISO)
regulation of transcription by RNA polymerase II  (IEA)
response to activity  (ISO)
response to arsenic-containing substance  (ISO)
response to ATP  (ISO)
response to estradiol  (ISO)
response to ethanol  (ISO)
response to glucose  (ISO)
response to nutrient  (ISO)
response to quercetin  (ISO)
response to xenobiotic stimulus  (ISO)
response to zinc ion  (ISO)
rhythmic synaptic transmission  (ISO)
social behavior  (ISO)
spindle assembly involved in female meiosis  (IEA)
synapse assembly  (ISO)
synapse maturation  (ISO)
T cell proliferation  (ISO)

Molecular Function
anaphase-promoting complex binding  (IEA)
calmodulin-dependent protein phosphatase activity  (IEA)
enzyme binding  (IEA)
histone H2AXS140 phosphatase activity  (IEA)
histone H2AXY142 phosphatase activity  (IEA)
identical protein binding  (IEA)
inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity  (IEA)
inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity  (IEA)
ionotropic glutamate receptor binding  (ISO)
MAP kinase serine/threonine phosphatase activity  (IEA)
molecular function inhibitor activity  (ISO)
myosin phosphatase activity  (IEA)
non-membrane spanning protein tyrosine phosphatase activity  (IEA)
PDZ domain binding  (IEA,ISO)
phosphatidylinositol phosphate phosphatase activity  (IEA)
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity  (IEA,ISO)
phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity  (IEA)
phosphatidylinositol-3-phosphate phosphatase activity  (IEA)
phosphoprotein phosphatase activity  (IEA)
platelet-derived growth factor receptor binding  (ISO)
protein binding  (ISO)
protein kinase binding  (ISO)
protein serine/threonine phosphatase activity  (IEA)
protein tyrosine kinase binding  (ISO)
protein tyrosine phosphatase activity  (IEA)
protein tyrosine phosphatase activity, metal-dependent  (IEA)
RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity  (IEA)
RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity  (IEA)
RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity  (IEA)
RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity  (IEA)
RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity  (IEA)
ubiquitin ligase activator activity  (ISO)
ubiquitin-specific protease binding  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PTEN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1981,308,058 - 81,412,386 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl981,309,099 - 81,409,146 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604841,972,612 - 42,077,014 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
PTEN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381087,863,625 - 87,971,930 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1087,862,638 - 87,971,930 (+)EnsemblGRCh38hg38GRCh38
GRCh371089,623,382 - 89,731,687 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361089,613,175 - 89,718,512 (+)NCBINCBI36Build 36hg18NCBI36
Build 341089,613,174 - 89,716,382NCBI
Celera1083,369,676 - 83,474,975 (+)NCBICelera
Cytogenetic Map10q23.31NCBI
HuRef1083,258,013 - 83,363,313 (+)NCBIHuRef
CHM1_11089,905,493 - 90,010,826 (+)NCBICHM1_1
T2T-CHM13v2.01088,747,528 - 88,855,830 (+)NCBIT2T-CHM13v2.0
Pten
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391932,734,977 - 32,803,560 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1932,734,897 - 32,803,560 (+)EnsemblGRCm39 Ensembl
GRCm381932,757,577 - 32,826,160 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1932,757,497 - 32,826,160 (+)EnsemblGRCm38mm10GRCm38
MGSCv371932,832,067 - 32,900,650 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361932,823,574 - 32,892,157 (+)NCBIMGSCv36mm8
Celera1933,541,182 - 33,610,051 (+)NCBICelera
Cytogenetic Map19C1NCBI
cM Map1928.14NCBI
Pten
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81240,043,707 - 240,110,330 (+)NCBIGRCr8
mRatBN7.21230,630,443 - 230,697,070 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1230,630,338 - 230,696,838 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1239,010,509 - 239,075,549 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01245,940,213 - 246,005,253 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01238,778,317 - 238,843,363 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01251,421,814 - 251,487,634 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1251,421,596 - 251,487,832 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01258,651,829 - 258,717,009 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41236,771,027 - 236,837,261 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11236,935,049 - 237,001,284 (+)NCBI
Celera1227,746,622 - 227,812,108 (+)NCBICelera
Cytogenetic Map1q52NCBI
Pten
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554255,014,147 - 5,091,829 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554255,007,811 - 5,091,829 (-)NCBIChiLan1.0ChiLan1.0
PTEN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2899,880,836 - 99,988,640 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11099,886,147 - 99,990,806 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01084,587,841 - 84,689,043 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11088,093,539 - 88,197,902 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1088,093,539 - 88,194,605 (+)Ensemblpanpan1.1panPan2
PTEN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12637,853,148 - 37,913,176 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2637,835,661 - 37,913,176 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2637,711,222 - 37,730,964 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02639,359,420 - 39,447,205 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2639,359,407 - 39,447,189 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12637,265,630 - 37,349,813 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02636,847,668 - 36,931,645 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02638,118,261 - 38,202,372 (+)NCBIUU_Cfam_GSD_1.0
Pten
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721377,454,602 - 77,542,975 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367351,252,414 - 1,338,323 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367351,252,414 - 1,338,318 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTEN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11499,929,590 - 100,021,619 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214108,911,519 - 109,003,081 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pten
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462479113,975,235 - 14,056,900 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007963471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCSAT00000004976   ⟹   ENSCSAP00000003218
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl981,309,099 - 81,409,146 (+)Ensembl
RefSeq Acc Id: XM_007963471   ⟹   XP_007961662
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1981,308,058 - 81,412,386 (+)NCBI
Vero_WHO_p1.0NW_02366604841,972,612 - 42,077,014 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007961662 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000003218
  ENSCSAP00000003218.1
RefSeq Acc Id: XP_007961662   ⟸   XM_007963471
- UniProtKB: A0A0D9R3M9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000003218   ⟸   ENSCSAT00000004976


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000006930 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000004976 ENTREZGENE
  ENSCSAT00000004976.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.1110 UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/TrEMBL
InterPro Bifunc_PIno_P3_Pase/Pase_PTEN UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  Dual-spec_lipid-protein_phosph UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  PTP_PTEN UniProtKB/TrEMBL
  Tensin_C2-dom UniProtKB/TrEMBL
  Tensin_phosphatase UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/TrEMBL
KEGG Report csab:103216211 UniProtKB/TrEMBL
NCBI Gene PTEN ENTREZGENE
PANTHER PHOSPHATASE WITH HOMOLOGY TO TENSIN UniProtKB/TrEMBL
  PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE AND DUAL-SPECIFICITY PROTEIN PHOSPHATASE PTEN UniProtKB/TrEMBL
Pfam PTEN_C2 UniProtKB/TrEMBL
  Tc-R-P UniProtKB/TrEMBL
PIRSF PTEN UniProtKB/TrEMBL
PROSITE C2_TENSIN UniProtKB/TrEMBL
  PPASE_TENSIN UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
SMART PTEN_C2 UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
  PTPlike_phytase UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
  SSF52799 UniProtKB/TrEMBL
UniProt A0A0D9R3M9 ENTREZGENE, UniProtKB/TrEMBL