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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Klrc1 | Mouse | 17beta-estradiol | multiple interactions | ISO | KLRC1 (Homo sapiens) | 6480464 | ESR1 protein affects the reaction [Estradiol promotes the reaction [NCOA2 protein binds to KLRC1 gene]] more ... | CTD | PMID:17962382 | Klrc1 | Mouse | 17beta-estradiol | multiple interactions | ISO | Klrc1 (Rattus norvegicus) | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of KLRC1 mRNA | CTD | PMID:32741896 | Klrc1 | Mouse | 17beta-estradiol | increases expression | ISO | KLRC1 (Homo sapiens) | 6480464 | Estradiol results in increased expression of KLRC1 mRNA | CTD | PMID:17962382 | Klrc1 | Mouse | 17beta-estradiol 3-benzoate | multiple interactions | ISO | Klrc1 (Rattus norvegicus) | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of KLRC1 mRNA | CTD | PMID:32741896 | Klrc1 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Klrc1 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of KLRC1 mRNA | CTD | PMID:21215274 | Klrc1 | Mouse | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | EXP | | 6480464 | 2 more ... | CTD | PMID:38648751 | Klrc1 | Mouse | 4,4'-diaminodiphenylmethane | decreases expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of KLRC1 mRNA | CTD | PMID:18648102 | Klrc1 | Mouse | 8-Br-cAMP | increases expression | ISO | KLRC1 (Homo sapiens) | 6480464 | 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of KLRC1 mRNA | CTD | PMID:22079614 | Klrc1 | Mouse | acrolein | affects expression | EXP | | 6480464 | Acrolein affects the expression of KLRC1 mRNA | CTD | PMID:18515264 | Klrc1 | Mouse | aflatoxin B1 | decreases methylation | ISO | KLRC1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of KLRC1 gene | CTD | PMID:27153756 | Klrc1 | Mouse | ammonium chloride | affects expression | ISO | Klrc1 (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of KLRC1 mRNA | CTD | PMID:16483693 | Klrc1 | Mouse | aristolochic acid A | increases expression | ISO | KLRC1 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of KLRC1 mRNA | CTD | PMID:33212167 | Klrc1 | Mouse | benzo[a]pyrene | increases expression | ISO | KLRC1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of KLRC1 mRNA | CTD | PMID:22316170 | Klrc1 | Mouse | benzo[a]pyrene | affects methylation | ISO | KLRC1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of KLRC1 promoter | CTD | PMID:27901495 | Klrc1 | Mouse | bisphenol A | decreases expression | ISO | Klrc1 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of KLRC1 mRNA | CTD | PMID:25181051 | Klrc1 | Mouse | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | Klrc1 | Mouse | chloroprene | decreases expression | EXP | | 6480464 | Chloroprene results in decreased expression of KLRC1 mRNA | CTD | PMID:23125180 | Klrc1 | Mouse | copper(II) sulfate | affects expression | ISO | KLRC1 (Homo sapiens) | 6480464 | Copper Sulfate affects the expression of KLRC1 mRNA | CTD | PMID:19549813 | Klrc1 | Mouse | Dibutyl phosphate | affects expression | ISO | KLRC1 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of KLRC1 mRNA | CTD | PMID:37042841 | Klrc1 | Mouse | flavonoids | decreases expression | ISO | Klrc1 (Rattus norvegicus) | 6480464 | Flavonoids results in decreased expression of KLRC1 mRNA | CTD | PMID:18035473 | Klrc1 | Mouse | folic acid | multiple interactions | ISO | KLRC1 (Homo sapiens) | 6480464 | [Folic Acid affects the susceptibility to Pemetrexed] which affects the expression of KLRC1 mRNA | CTD | PMID:22975265 | Klrc1 | Mouse | genistein | decreases expression | EXP | | 6480464 | Genistein results in decreased expression of KLRC1 mRNA | CTD | PMID:32186404 | Klrc1 | Mouse | ledipasvir | decreases expression | ISO | KLRC1 (Homo sapiens) | 40400920 | ledipasvir co-treated with sofosbuvir decreases expression of NCR1 protein in natural killer cells | RGD | | Klrc1 | Mouse | lipopolysaccharide | decreases expression | ISO | KLRC1 (Homo sapiens) | 6480464 | Lipopolysaccharides results in decreased expression of KLRC1 mRNA | CTD | PMID:35811015 | Klrc1 | Mouse | lipopolysaccharide | multiple interactions | ISO | KLRC1 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of KLRC1 mRNA | CTD | PMID:35811015 | Klrc1 | Mouse | pemetrexed | multiple interactions | ISO | KLRC1 (Homo sapiens) | 6480464 | [Folic Acid affects the susceptibility to Pemetrexed] which affects the expression of KLRC1 mRNA | CTD | PMID:22975265 | Klrc1 | Mouse | pentanal | decreases expression | ISO | KLRC1 (Homo sapiens) | 6480464 | pentanal results in decreased expression of KLRC1 mRNA | CTD | PMID:26079696 | Klrc1 | Mouse | pregnenolone 16alpha-carbonitrile | increases expression | ISO | Klrc1 (Rattus norvegicus) | 6480464 | Pregnenolone Carbonitrile results in increased expression of KLRC1 mRNA | CTD | PMID:19162173 | Klrc1 | Mouse | raloxifene | increases expression | ISO | KLRC1 (Homo sapiens) | 6480464 | Raloxifene Hydrochloride results in increased expression of KLRC1 mRNA | CTD | PMID:17962382 | Klrc1 | Mouse | ribavirin | affects expression | ISO | KLRC1 (Homo sapiens) | 40818079 | Ribavirin co-treated with Interferon alfa-2a affects expression of KLRC1 protein in Natural Killer cells | RGD | | Klrc1 | Mouse | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | KLRC1 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of KLRC1 mRNA | CTD | PMID:35811015 | Klrc1 | Mouse | silicon dioxide | decreases expression | ISO | KLRC1 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of KLRC1 mRNA | CTD | PMID:23806026 and PMID:25895662 | Klrc1 | Mouse | silicon dioxide | increases expression | EXP | | 6480464 | Silicon Dioxide results in increased expression of KLRC1 mRNA | CTD | PMID:29341224 | Klrc1 | Mouse | sofosbuvir | decreases expression | ISO | KLRC1 (Homo sapiens) | 40400920 | sofosbuvir co-treated with ledipasvir decreased expression of NCR1 protein in natural killer cells | RGD | | Klrc1 | Mouse | tamoxifen | increases expression | ISO | KLRC1 (Homo sapiens) | 6480464 | Tamoxifen results in increased expression of KLRC1 mRNA | CTD | PMID:17962382 | Klrc1 | Mouse | testosterone | multiple interactions | ISO | Klrc1 (Rattus norvegicus) | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of KLRC1 mRNA | CTD | PMID:32741896 | Klrc1 | Mouse | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of KLRC1 mRNA | CTD | PMID:23557971 | Klrc1 | Mouse | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of KLRC1 mRNA | CTD | PMID:29264374 | Klrc1 | Mouse | triphenyl phosphate | affects expression | ISO | KLRC1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of KLRC1 mRNA | CTD | PMID:37042841 | |