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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:polyprenol
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Accession:CHEBI:26199 term browser browse the term
Definition:Any member of the class of prenols possessing the general formula H-[CH2C(Me)=CHCH2]nOH in which the carbon skeleton is composed of more than one isoprene units.
Synonyms:related_synonym: Formula=(C5H8)nC10H18O;   polyprenols
 alt_id: CHEBI:8317
 xref: KEGG:C06081



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2-trans,6-trans,10-trans-geranylgeranyl diphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [kuwanon G results in increased expression of ABCB1 protein] CTD PMID:29355567 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [kuwanon G results in increased expression of ABCG1 protein] CTD PMID:29355567 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of AKT1 mRNA]
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased phosphorylation of AKT1 protein]
CTD PMID:18031796 PMID:33034787 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of BCL2 mRNA] CTD PMID:18031796 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in decreased expression of BIRC5 protein] CTD PMID:17472962 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bmp2 bone morphogenetic protein 2 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]] CTD PMID:18310456 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP
geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin results in increased activity of CASP3 protein]; geranylgeranyl pyrophosphate inhibits the reaction [cerivastatin results in increased activity of CASP3 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased activity of and results in increased cleavage of CASP3 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in increased activity of CASP3 protein] CTD PMID:15200425 PMID:16470222 PMID:18766339 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TGFB1 results in increased expression of CCN2 mRNA]] CTD PMID:15298857 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccna2 cyclin A2 multiple interactions EXP geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CCNA2 protein] CTD PMID:26577051 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccne1 cyclin E1 multiple interactions EXP geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CCNE1 protein] CTD PMID:26577051 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Cd40 CD40 molecule multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CD40 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CD40 protein]] CTD PMID:17507688 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions EXP geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CDK1 protein] CTD PMID:26577051 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions EXP geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CDK2 protein] CTD PMID:26577051 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in increased expression of CDKN1A protein] CTD PMID:18625202 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of COL1A1 mRNA] CTD PMID:16575855 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Crp C-reactive protein multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [CRP results in increased expression of RETN mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [CRP results in increased secretion of RETN protein]] CTD PMID:18023360 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions EXP geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CYP17A1 mRNA] CTD PMID:21918126 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [resveratrol results in increased expression of CYP7A1 mRNA] CTD PMID:22607622 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of F3 mRNA] CTD PMID:18031796 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Fbxo32 F-box protein 32 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased expression of FBXO32 mRNA]; geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased expression of FBXO32 protein] CTD PMID:19406843 NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased phosphorylation of and affects the localization of FOXO1 protein] CTD PMID:33034787 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Ggps1 geranylgeranyl diphosphate synthase 1 decreases activity ISO geranylgeranyl pyrophosphate analog results in decreased activity of GGPS1 protein CTD PMID:16787319 NCBI chr17:51,263,262...51,282,471
Ensembl chr17:51,263,263...51,276,220
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO [Lovastatin results in decreased activity of HMGCR protein] which results in decreased abundance of geranylgeranyl pyrophosphate CTD PMID:17208200 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased activity of HRAS protein]] CTD PMID:18625914 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of ICAM1 protein]] CTD PMID:10946302 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifng interferon gamma multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CD40 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CD40 protein]] CTD PMID:17507688 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il12b interleukin 12B multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B protein] CTD PMID:15187114 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO
EXP
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased expression of MMP9 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]]
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in decreased expression of NOS2 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in increased abundance of Nitric Oxide]]
CTD PMID:15705589 PMID:15728660 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased secretion of IL1B protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of ICAM1 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]] CTD PMID:10946302 PMID:17075836 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of IL6 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased secretion of IL6 protein]]
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [[Lipopolysaccharides co-treated with TNF] results in increased expression of IL6 protein]]
CTD PMID:16511915 PMID:17075836 PMID:17729120 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Irf4 interferon regulatory factor 4 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of IRF4 mRNA]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of IRF4 protein] CTD PMID:33034787 NCBI chr17:33,721,800...33,742,570
Ensembl chr17:33,721,811...33,740,070
JBrowse link
G Lep leptin multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of LEP mRNA]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased secretion of LEP protein] CTD PMID:19254925 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin results in decreased phosphorylation of MAPK1 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]] CTD PMID:16470222 PMID:18625914 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin results in decreased phosphorylation of MAPK3 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]] CTD PMID:16470222 PMID:18625914 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mbp myelin basic protein multiple interactions EXP geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased expression of MBP mRNA] CTD PMID:20578043 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of MMP1]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of MMP1 mRNA]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of MMP1 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased secretion of MMP1 protein] CTD PMID:17303772 PMID:18625914 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO
EXP
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased expression of MMP9 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]]
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Smoke analog results in increased expression of MMP9 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Smoke analog results in increased expression of MMP9]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Smoke analog results in increased secretion of MMP9 protein]]
CTD PMID:15728660 PMID:19299917 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mstn myostatin multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in increased expression of MSTN mRNA]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in increased expression of MSTN protein] CTD PMID:33034787 NCBI chr 9:48,452,533...48,458,933
Ensembl chr 9:48,452,533...48,458,933
JBrowse link
G Mvk mevalonate kinase multiple interactions
decreases chemical synthesis
decreases activity
ISO geranylgeranyl pyrophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; geranylgeranyl pyrophosphate inhibits the reaction [MVK protein results in increased phosphorylation of Mevalonic Acid]
MVK protein mutant form results in decreased chemical synthesis of geranylgeranyl pyrophosphate
geranylgeranyl pyrophosphate results in decreased activity of MVK protein
CTD PMID:9392419 PMID:24073415 NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased degradation of NFKBIA protein]] CTD PMID:17075836 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in decreased expression of NOS2 protein]] CTD PMID:15705589 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 decreases activity ISO geranylgeranyl pyrophosphate results in decreased activity of NR1H3 protein CTD PMID:22607622 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of NR4A3 mRNA] CTD PMID:16005304 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [TNFSF10 protein promotes the reaction [Simvastatin results in increased cleavage of PARP1 protein]] CTD PMID:21910007 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased expression of MMP9 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]] CTD PMID:15728660 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Plat plasminogen activator, tissue type multiple interactions EXP geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased expression of PLAT protein] CTD PMID:10412747 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Pon1 paraoxonase 1 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in increased expression of PON1 mRNA] CTD PMID:14500290 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions EXP geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased expression of PPARG mRNA] CTD PMID:20578043 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions EXP geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased expression of PTEN mRNA] CTD PMID:20578043 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin inhibits the reaction [Glucose results in increased localization of RAC1 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased activity of RAC1 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased localization of RAC1 protein]] CTD PMID:17279352 PMID:18625914 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Retn resistin multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [CRP results in increased expression of RETN mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [CRP results in increased secretion of RETN protein]] CTD PMID:18023360 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620
JBrowse link
G Rhoa ras homolog family member A multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin results in decreased activity of RHOA protein]; geranylgeranyl pyrophosphate inhibits the reaction [Atorvastatin results in increased localization of RHOA protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin affects the localization of and results in decreased activity of RHOA protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in decreased activity of RHOA protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased activity of RHOA protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased activity of RHOA protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in increased localization of RHOA protein]; Simvastatin inhibits the reaction [geranylgeranyl pyrophosphate affects the localization of RHOA protein]
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF affects the localization of RHOA protein]]
CTD PMID:16005304 PMID:16470222 PMID:17075836 PMID:18031796 PMID:18310456 More... NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]] CTD PMID:18310456 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Sele selectin E multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]] CTD PMID:10946302 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Sox10 SRY-box transcription factor 10 multiple interactions EXP geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased expression of SOX10 mRNA] CTD PMID:20578043 NCBI chr 7:110,725,274...110,734,651
Ensembl chr 7:110,725,274...110,735,544
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions
increases expression
ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of STAT1 mRNA]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of STAT1 protein]
geranylgeranyl pyrophosphate results in increased expression of STAT1 protein
CTD PMID:17507688 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TGFB1 results in increased expression of CCN2 mRNA]] CTD PMID:15298857 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased activity of RHOA protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased degradation of NFKBIA protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of IL6 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased secretion of IL1B protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased secretion of IL6 protein]]
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF affects the localization of RHOA protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [[Lipopolysaccharides co-treated with TNF] results in increased abundance of Nitric Oxide]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [[Lipopolysaccharides co-treated with TNF] results in increased expression of IL6 protein]]
CTD PMID:16511915 PMID:17075836 PMID:17729120 PMID:18310456 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [TNFSF10 protein promotes the reaction [Simvastatin results in increased cleavage of PARP1 protein]] CTD PMID:21910007 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in increased expression of VEGFA mRNA] CTD PMID:18356691 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
2-trans,6-trans-farnesyl diphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin results in decreased phosphorylation of AKT1 protein] CTD PMID:33034787 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Lovastatin results in decreased expression of BIRC5 protein] CTD PMID:17472962 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bmp2 bone morphogenetic protein 2 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]] CTD PMID:18310456 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP
farnesyl pyrophosphate inhibits the reaction [Lovastatin results in increased activity of and results in increased cleavage of CASP3 protein]
farnesyl pyrophosphate inhibits the reaction [Simvastatin results in increased activity of CASP3 protein]
CTD PMID:15200425 PMID:18766339 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions EXP farnesyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CYP17A1 mRNA] CTD PMID:21918126 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Fnta farnesyltransferase, CAAX box, subunit alpha multiple interactions EXP [FNTA protein binds to FNTB protein] binds to [farnesyl pyrophosphate analog co-treated with KRAS protein] CTD PMID:10673434 NCBI chr16:66,065,131...66,083,460
Ensembl chr16:66,065,132...66,083,460
JBrowse link
G Fntb farnesyltransferase, CAAX box, subunit beta multiple interactions EXP [FNTA protein binds to FNTB protein] binds to [farnesyl pyrophosphate analog co-treated with KRAS protein] CTD PMID:10673434 NCBI chr 6:95,536,540...95,619,587
Ensembl chr 6:95,470,683...95,619,586
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of FOS mRNA] CTD PMID:16005304 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin results in decreased phosphorylation of FOXO1 protein] CTD PMID:33034787 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO [Lovastatin results in decreased activity of HMGCR protein] which results in decreased abundance of farnesyl pyrophosphate CTD PMID:17208200 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased activity of HRAS protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased localization of HRAS protein]] CTD PMID:18625914 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of ICAM1 protein]] CTD PMID:10946302 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il12b interleukin 12B multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B protein] CTD PMID:15187114 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of ICAM1 protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]] CTD PMID:10946302 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions EXP [FNTA protein binds to FNTB protein] binds to [farnesyl pyrophosphate analog co-treated with KRAS protein] CTD PMID:10673434 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK1 protein]] CTD PMID:18310456 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK3 protein]] CTD PMID:18310456 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein]] CTD PMID:18310456 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Smoke analog results in increased expression of MMP9 mRNA]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Smoke analog results in increased secretion of MMP9 protein]] CTD PMID:19299917 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mvk mevalonate kinase decreases activity
decreases chemical synthesis
multiple interactions
ISO farnesyl pyrophosphate results in decreased activity of MVK protein
MVK protein mutant form results in decreased chemical synthesis of farnesyl pyrophosphate
farnesyl pyrophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; farnesyl pyrophosphate inhibits the reaction [MVK protein results in increased phosphorylation of Mevalonic Acid]
CTD PMID:9392419 PMID:24073415 NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882
JBrowse link
G Pon1 paraoxonase 1 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [pitavastatin results in increased expression of PON1 mRNA]; farnesyl pyrophosphate inhibits the reaction [Simvastatin results in increased expression of PON1 mRNA] CTD PMID:14500290 PMID:15690306 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased activity of RAC1 protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased localization of RAC1 protein]] CTD PMID:18625914 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Rhoa ras homolog family member A multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in decreased activity of RHOA protein]]
farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF affects the localization of RHOA protein]]
CTD PMID:18310456 PMID:18625914 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]] CTD PMID:18310456 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Sele selectin E multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]] CTD PMID:10946302 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF affects the localization of RHOA protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK1 protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK3 protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein]] CTD PMID:18310456 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
dolichyl phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mvk mevalonate kinase decreases activity
multiple interactions
ISO dolichol monophosphate results in decreased activity of MVK protein
dolichol monophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; dolichol monophosphate inhibits the reaction [MVK protein results in increased phosphorylation of Mevalonic Acid]
CTD PMID:9392419 NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882
JBrowse link
farnesol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa1a acetyl-CoA acyltransferase 1A multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACAA1 mRNA CTD PMID:30611723 NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:119,079,775...119,088,624
JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 multiple interactions
increases expression
ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACAA2 mRNA
Farnesol analog results in increased expression of ACAA2 mRNA
CTD PMID:30611723 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACADM mRNA CTD PMID:30611723 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Acads acyl-CoA dehydrogenase short chain multiple interactions
increases expression
ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACADS mRNA
Farnesol analog results in increased expression of ACADS mRNA
CTD PMID:30611723 NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 increases expression ISO Farnesol analog results in increased expression of ACAT1 mRNA CTD PMID:30611723 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 increases expression ISO Farnesol analog results in increased expression of ACAT2 mRNA CTD PMID:30611723 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
JBrowse link
G Acot1 acyl-CoA thioesterase 1 multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACOT1 mRNA CTD PMID:30611723 NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
JBrowse link
G Acot12 acyl-CoA thioesterase 12 increases expression
multiple interactions
ISO Farnesol analog results in increased expression of ACOT12 mRNA
[Farnesol analog co-treated with Oleic Acid] results in increased expression of ACOT12 mRNA
CTD PMID:30611723 NCBI chr 2:22,986,867...23,027,538
Ensembl chr 2:22,986,626...23,027,536
JBrowse link
G Acot6 acyl-CoA thioesterase 6 multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in decreased expression of ACOT6 mRNA CTD PMID:30611723 NCBI chr 6:103,732,372...103,741,446
Ensembl chr 6:103,732,372...103,741,446
JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA CTD PMID:30611723 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Acox2 acyl-CoA oxidase 2 decreases expression
increases expression
ISO Farnesol analog results in decreased expression of ACOX2 mRNA
Farnesol analog results in increased expression of ACOX2 mRNA
CTD PMID:30611723 NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACSL4 mRNA CTD PMID:30611723 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACSL5 mRNA CTD PMID:30611723 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
JBrowse link
G Agpat1 1-acylglycerol-3-phosphate O-acyltransferase 1 multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in decreased expression of AGPAT1 mRNA CTD PMID:30611723 NCBI chr20:4,135,955...4,144,880
Ensembl chr20:4,135,957...4,145,278
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases chemical synthesis ISO AKR1B10 protein results in increased chemical synthesis of Farnesol CTD PMID:21187079 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 increases expression ISO Farnesol results in increased expression of AKR1C1 mRNA CTD PMID:30806763 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases chemical synthesis
multiple interactions
ISO AKR1C3 protein results in increased chemical synthesis of Farnesol
[Flurbiprofen results in decreased activity of AKR1C3 protein] which results in increased metabolism of Farnesol; [tolfenamic acid results in decreased activity of AKR1C3 protein] which results in increased metabolism of Farnesol
CTD PMID:21187079 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Apoa5 apolipoprotein A5 multiple interactions
increases expression
ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of APOA5 mRNA
Farnesol analog results in increased expression of APOA5 mRNA
CTD PMID:30611723 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
JBrowse link
G Apoc4 apolipoprotein C4 decreases expression ISO Farnesol analog results in decreased expression of APOC4 mRNA CTD PMID:30611723 NCBI chr 1:79,335,745...79,339,942
Ensembl chr 1:79,335,745...79,339,981
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Farnesol results in increased expression of ATF3 mRNA CTD PMID:27965148 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO Farnesol results in increased expression of BAK1 protein CTD PMID:12530055 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Casp3 caspase 3 increases activity
decreases activity
ISO
EXP
Farnesol results in increased activity of CASP3 protein
Farnesol results in decreased activity of CASP3 protein
CTD PMID:10733934 PMID:21453689 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase increases expression
multiple interactions
EXP
ISO
Farnesol results in increased expression of CAT protein
Farnesol inhibits the reaction [Acetaminophen results in decreased activity of CAT protein]
Farnesol inhibits the reaction [Tobacco Smoke Pollution results in decreased activity of CAT protein]
CTD PMID:18793622 PMID:21453689 PMID:37458150 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases secretion ISO Farnesol results in increased secretion of CCL4 protein CTD PMID:30806763 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Farnesol results in decreased expression of CCNA2 protein CTD PMID:17138864 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Farnesol results in decreased expression of CCNB1 protein CTD PMID:17138864 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression
multiple interactions
ISO Farnesol results in decreased expression of CDK2 protein
Farnesol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein]; Farnesol promotes the reaction [CDKN1B protein binds to and results in decreased activity of CDK2 protein]
CTD PMID:17138864 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
increases response to substance
ISO Farnesol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein]
Farnesol results in increased expression of CDKN1A protein
CDKN1A protein results in increased susceptibility to Farnesol
CTD PMID:17138864 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases response to substance
increases expression
multiple interactions
ISO CDKN1B protein results in increased susceptibility to Farnesol
Farnesol results in increased expression of CDKN1B protein
Farnesol promotes the reaction [CDKN1B protein binds to and results in decreased activity of CDK2 protein]
CTD PMID:17138864 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cox10 cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 decreases expression ISO Farnesol analog results in decreased expression of COX10 mRNA CTD PMID:30611723 NCBI chr10:48,630,993...48,742,805
Ensembl chr10:48,630,676...48,746,667
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of CPT1A mRNA CTD PMID:30611723 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity EXP Farnesol results in increased activity of CYP19A1 protein CTD PMID:15840382 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
increases expression
EXP
ISO
Farnesol results in increased activity of CYP1A1 protein
Farnesol results in increased expression of CYP1A1 mRNA
CTD PMID:15840382 PMID:30806763 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases activity
multiple interactions
EXP
ISO
Farnesol results in increased activity of CYP1A2 protein
Farnesol analog inhibits the reaction [Oleic Acid results in decreased expression of CYP1A2 mRNA]
CTD PMID:15840382 PMID:30611723 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 increases activity EXP Farnesol results in increased activity of CYP2A1 protein CTD PMID:15840382 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 increases activity EXP Farnesol results in increased activity of CYP2A2 protein CTD PMID:15840382 NCBI chr 1:82,263,833...82,289,487
Ensembl chr 1:82,263,833...82,289,487
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 increases activity EXP Farnesol results in increased activity of CYP2A3 protein CTD PMID:15840382 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases activity EXP Farnesol results in increased activity of CYP2B1 protein CTD PMID:15840382 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases activity EXP Farnesol results in increased activity of CYP2B2 protein CTD PMID:15840382 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
increases expression
ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of CYP2B6 mRNA; Farnesol analog inhibits the reaction [Oleic Acid results in decreased expression of CYP2B6 mRNA]
Farnesol analog results in increased expression of CYP2B6 mRNA; Farnesol results in increased expression of CYP2B6 mRNA
CTD PMID:30611723 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 increases activity EXP Farnesol results in increased activity of CYP2C11 protein CTD PMID:15840382 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 increases activity EXP Farnesol results in increased activity of CYP2C12 protein CTD PMID:15840382 NCBI chr 1:238,699,859...238,757,011
Ensembl chr 1:238,699,854...238,757,019
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases activity
multiple interactions
decreases expression
EXP
ISO
Farnesol results in increased activity of CYP2E1 protein
[Farnesol analog co-treated with Oleic Acid] results in increased expression of CYP2E1 mRNA; Farnesol analog inhibits the reaction [Oleic Acid results in increased expression of CYP2E1 mRNA]
Farnesol analog results in decreased expression of CYP2E1 mRNA; Farnesol results in decreased expression of CYP2E1 mRNA
CTD PMID:15840382 PMID:30611723 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases activity
increases expression
multiple interactions
EXP
ISO
Farnesol results in increased activity of CYP3A2 protein
Farnesol results in increased expression of CYP3A4 mRNA
Farnesol analog inhibits the reaction [Oleic Acid results in decreased expression of CYP3A4 mRNA]
CTD PMID:15840382 PMID:30611723 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases activity EXP Farnesol results in increased activity of CYP3A23-3A1 protein CTD PMID:15840382 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases activity EXP Farnesol results in increased activity of CYP4A1 protein CTD PMID:15840382 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
JBrowse link
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 increases activity EXP Farnesol results in increased activity of CYP4A2 protein CTD PMID:15840382 NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165
JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 increases activity EXP Farnesol results in increased activity of CYP4A3 protein CTD PMID:15840382 NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463
JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in decreased expression of DECR1 mRNA CTD PMID:30611723 NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 decreases expression ISO Farnesol analog results in decreased expression of DGAT1 mRNA CTD PMID:30611723 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of DGAT2 mRNA CTD PMID:30611723 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO Farnesol results in increased expression of DNAJB4 mRNA CTD PMID:27965148 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression ISO Farnesol analog results in increased expression of ECH1 mRNA CTD PMID:30611723 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
JBrowse link
G Egf epidermal growth factor multiple interactions ISO Farnesol analog inhibits the reaction [EGF protein results in increased activity of RHOA protein]; Farnesol analog results in decreased susceptibility to [INS protein co-treated with EGF protein] CTD PMID:24587105 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of ELOVL6 mRNA CTD PMID:30611723 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression ISO Farnesol analog results in increased expression of FABP1 mRNA CTD PMID:30611723 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression ISO Farnesol results in increased expression of FABP4 mRNA CTD PMID:30806763 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of FASN mRNA CTD PMID:30611723 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression ISO Farnesol analog results in increased expression of FDFT1 mRNA CTD PMID:30611723 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fnta farnesyltransferase, CAAX box, subunit alpha multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of FNTA mRNA CTD PMID:30611723 NCBI chr16:66,065,131...66,083,460
Ensembl chr16:66,065,132...66,083,460
JBrowse link
G Fntb farnesyltransferase, CAAX box, subunit beta decreases expression ISO Farnesol analog results in decreased expression of FNTB mRNA CTD PMID:30611723 NCBI chr 6:95,536,540...95,619,587
Ensembl chr 6:95,470,683...95,619,586
JBrowse link
G Gpat4 glycerol-3-phosphate acyltransferase 4 multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of GPAT4 mRNA CTD PMID:30611723 NCBI chr16:68,819,031...68,852,903
Ensembl chr16:68,819,079...68,852,901
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO Farnesol inhibits the reaction [Acetaminophen results in increased expression of GPT protein] CTD PMID:37458150 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gsr glutathione-disulfide reductase increases activity
multiple interactions
increases expression
EXP
ISO
Farnesol results in increased activity of GSR protein
Farnesol inhibits the reaction [Acetaminophen results in decreased activity of GSR protein]
Farnesol results in increased expression of GSR protein
CTD PMID:15840382 PMID:21453689 PMID:37458150 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha increases expression
multiple interactions
ISO Farnesol analog results in increased expression of HADHA mRNA
[Farnesol analog co-treated with Oleic Acid] results in increased expression of HADHA mRNA
CTD PMID:30611723 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta increases expression
multiple interactions
ISO Farnesol analog results in increased expression of HADHB mRNA
[Farnesol analog co-treated with Oleic Acid] results in increased expression of HADHB mRNA
CTD PMID:30611723 NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases expression
decreases activity
ISO
EXP
[Farnesol analog co-treated with Oleic Acid] results in increased expression of HMGCR mRNA
Farnesol results in increased expression of HMGCR protein
Farnesol results in decreased activity of HMGCR protein
CTD PMID:12477733 PMID:16332721 PMID:30611723 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Farnesol results in increased expression of HMOX1 mRNA CTD PMID:30806763 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO Farnesol inhibits the reaction [Simvastatin results in decreased farnesylation of and affects the localization of HRAS protein] CTD PMID:12477733 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Farnesol results in increased expression of ICAM1 mRNA CTD PMID:30806763 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO Farnesol inhibits the reaction [Acetaminophen results in increased expression of IKBKB mRNA] CTD PMID:37458150 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Il16 interleukin 16 increases secretion ISO Farnesol results in increased secretion of IL16 protein CTD PMID:30806763 NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Farnesol results in increased expression of IL1A mRNA CTD PMID:30806763 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Farnesol inhibits the reaction [[MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased expression of IL1B protein]
Farnesol inhibits the reaction [[Alendronate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]; Farnesol inhibits the reaction [Acetaminophen results in increased expression of IL1B protein]
CTD PMID:20304105 PMID:37458150 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1r2 interleukin 1 receptor type 2 increases expression ISO Farnesol results in increased expression of IL1R2 mRNA CTD PMID:30806763 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Farnesol inhibits the reaction [Acetaminophen results in increased expression of IL6 mRNA] CTD PMID:37458150 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins2 insulin 2 multiple interactions ISO Farnesol analog results in decreased susceptibility to [INS protein co-treated with EGF protein] CTD PMID:24587105 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Lipc lipase C, hepatic type increases expression ISO Farnesol analog results in increased expression of LIPC mRNA CTD PMID:30611723 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Lpin1 lipin 1 multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of LPIN1 mRNA CTD PMID:30611723 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
G Lpin3 lipin 3 decreases expression ISO Farnesol analog results in decreased expression of LPIN3 mRNA CTD PMID:30611723 NCBI chr 3:149,533,719...149,558,494
Ensembl chr 3:149,534,051...149,558,327
JBrowse link
G Mlxipl MLX interacting protein-like multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in decreased expression of MLXIPL mRNA CTD PMID:30611723 NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112
JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression ISO Farnesol results in increased expression of MMP3 mRNA CTD PMID:30806763 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mvk mevalonate kinase decreases activity
multiple interactions
ISO Farnesol results in decreased activity of MVK protein
Farnesol inhibits the reaction [[MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased expression of IL1B protein]; Farnesol inhibits the reaction [MVK gene mutant form results in increased susceptibility to Lipopolysaccharides]; Farnesol inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; Farnesol inhibits the reaction [MVK protein results in increased phosphorylation of Mevalonic Acid]
CTD PMID:9392419 PMID:20304105 NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882
JBrowse link
G Myl9 myosin light chain 9 multiple interactions ISO Farnesol analog inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MYL9 protein] CTD PMID:24587105 NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases activity EXP Farnesol results in increased activity of NQO1 protein CTD PMID:15840382 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression
multiple interactions
ISO Farnesol analog results in decreased expression of NR0B2 mRNA
[Farnesol analog co-treated with Oleic Acid] results in decreased expression of NR0B2 mRNA
CTD PMID:30611723 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions
decreases expression
ISO Farnesol binds to and results in increased activity of NR1H4 protein
Farnesol analog results in decreased expression of NR1H4 mRNA
CTD PMID:15491415 PMID:30611723 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions
decreases expression
ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of PCK1 mRNA
Farnesol analog results in decreased expression of PCK1 mRNA
CTD PMID:30611723 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pdss1 decaprenyl diphosphate synthase subunit 1 increases expression ISO Farnesol analog results in increased expression of PDSS1 mRNA CTD PMID:30611723 NCBI chr17:85,059,953...85,098,739
Ensembl chr17:85,060,106...85,098,730
JBrowse link
G Plin2 perilipin 2 increases expression
multiple interactions
ISO Farnesol analog results in increased expression of PLIN2 mRNA
[Farnesol analog co-treated with Oleic Acid] results in increased expression of PLIN2 mRNA
CTD PMID:30611723 NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of PPARA mRNA; Farnesol inhibits the reaction [cerivastatin promotes the reaction [Bezafibrate results in increased activity of [PPARA protein binds to RXRA protein]]] CTD PMID:11779144 PMID:30611723 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
increases expression
ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of PPARG mRNA
Farnesol analog results in increased expression of PPARG mRNA
CTD PMID:30611723 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions EXP Farnesol inhibits the reaction [Atorvastatin inhibits the reaction [TNF protein results in decreased expression of PPARGC1A protein]] CTD PMID:22343369 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Rabggta Rab geranylgeranyltransferase subunit alpha multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in decreased expression of RABGGTA mRNA CTD PMID:30611723 NCBI chr15:29,206,328...29,213,398
Ensembl chr15:29,206,157...29,213,348
JBrowse link
G Rabggtb Rab geranylgeranyltransferase subunit beta multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in decreased expression of RABGGTB mRNA CTD PMID:30611723 NCBI chr 2:242,844,758...242,850,951
Ensembl chr 2:242,844,762...242,851,050
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO Farnasol inhibits the reaction [Ropivacaine decreases activity of RAC1 protein in esophageal carcinoma cells] RGD PMID:29777701 RGD:155230817 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Rhoa ras homolog family member A multiple interactions EXP
ISO
Farnesol inhibits the reaction [Lovastatin affects the localization of RHOA protein]
Farnesol analog inhibits the reaction [EGF protein results in increased activity of RHOA protein]; Farnesol analog inhibits the reaction [lysophosphatidic acid results in increased activity of RHOA protein]
CTD PMID:9398081 PMID:24587105 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rhoc ras homolog family member C multiple interactions ISO Farnesol analog inhibits the reaction [lysophosphatidic acid results in increased activity of RHOC protein] CTD PMID:24587105 NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO Farnesol inhibits the reaction [cerivastatin promotes the reaction [Bezafibrate results in increased activity of [PPARA protein binds to RXRA protein]]] CTD PMID:11779144 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in decreased expression of SCD mRNA CTD PMID:30611723 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Serpinb3 serpin family B member 3 increases expression ISO Farnesol results in increased expression of SERPINB3 mRNA CTD PMID:30806763 NCBI chr13:23,274,120...23,280,660
Ensembl chr13:23,274,484...23,313,682
JBrowse link
G Slc25a20 solute carrier family 25 member 20 multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of SLC25A20 mRNA CTD PMID:30611723 NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512
JBrowse link
G Slc27a1 solute carrier family 27 member 1 multiple interactions ISO [Farnesol analog co-treated with Oleic Acid] results in increased expression of SLC27A1 mRNA CTD PMID:30611723 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
JBrowse link
G Slc27a2 solute carrier family 27 member 2 increases expression ISO Farnesol analog results in increased expression of SLC27A2 mRNA CTD PMID:30611723 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Farnesol results in increased expression of SLC7A11 mRNA CTD PMID:30806763 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP
ISO
Farnesol inhibits the reaction [Atorvastatin inhibits the reaction [TNF protein results in decreased expression of PPARGC1A protein]]
Farnesol inhibits the reaction [Acetaminophen results in increased expression of TNF protein]
Farnesol results in increased expression of TNF mRNA
CTD PMID:22343369 PMID:30806763 PMID:37458150 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of Farnesol CTD PMID:15320866 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of Farnesol CTD PMID:15320866 NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 increases glucuronidation ISO UGT1A4 protein results in increased glucuronidation of Farnesol CTD PMID:15320866 NCBI chr 9:88,762,250...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases glucuronidation ISO UGT1A6 protein results in increased glucuronidation of Farnesol CTD PMID:15320866 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of Farnesol CTD PMID:15320866 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 increases glucuronidation ISO UGT2B7 protein results in increased glucuronidation of Farnesol CTD PMID:15320866 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
JBrowse link
farnesyl diphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin results in decreased phosphorylation of AKT1 protein] CTD PMID:33034787 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Lovastatin results in decreased expression of BIRC5 protein] CTD PMID:17472962 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bmp2 bone morphogenetic protein 2 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]] CTD PMID:18310456 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP
farnesyl pyrophosphate inhibits the reaction [Lovastatin results in increased activity of and results in increased cleavage of CASP3 protein]
farnesyl pyrophosphate inhibits the reaction [Simvastatin results in increased activity of CASP3 protein]
CTD PMID:15200425 PMID:18766339 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions EXP farnesyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CYP17A1 mRNA] CTD PMID:21918126 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Fnta farnesyltransferase, CAAX box, subunit alpha multiple interactions EXP [FNTA protein binds to FNTB protein] binds to [farnesyl pyrophosphate analog co-treated with KRAS protein] CTD PMID:10673434 NCBI chr16:66,065,131...66,083,460
Ensembl chr16:66,065,132...66,083,460
JBrowse link
G Fntb farnesyltransferase, CAAX box, subunit beta multiple interactions EXP [FNTA protein binds to FNTB protein] binds to [farnesyl pyrophosphate analog co-treated with KRAS protein] CTD PMID:10673434 NCBI chr 6:95,536,540...95,619,587
Ensembl chr 6:95,470,683...95,619,586
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of FOS mRNA] CTD PMID:16005304 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin results in decreased phosphorylation of FOXO1 protein] CTD PMID:33034787 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO [Lovastatin results in decreased activity of HMGCR protein] which results in decreased abundance of farnesyl pyrophosphate CTD PMID:17208200 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased activity of HRAS protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased localization of HRAS protein]] CTD PMID:18625914 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of ICAM1 protein]] CTD PMID:10946302 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il12b interleukin 12B multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B protein] CTD PMID:15187114 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of ICAM1 protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]] CTD PMID:10946302 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions EXP [FNTA protein binds to FNTB protein] binds to [farnesyl pyrophosphate analog co-treated with KRAS protein] CTD PMID:10673434 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK1 protein]] CTD PMID:18310456 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK3 protein]] CTD PMID:18310456 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein]] CTD PMID:18310456 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Smoke analog results in increased expression of MMP9 mRNA]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Smoke analog results in increased secretion of MMP9 protein]] CTD PMID:19299917 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mvk mevalonate kinase decreases activity
decreases chemical synthesis
multiple interactions
ISO farnesyl pyrophosphate results in decreased activity of MVK protein
MVK protein mutant form results in decreased chemical synthesis of farnesyl pyrophosphate
farnesyl pyrophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; farnesyl pyrophosphate inhibits the reaction [MVK protein results in increased phosphorylation of Mevalonic Acid]
CTD PMID:9392419 PMID:24073415 NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882
JBrowse link
G Pon1 paraoxonase 1 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [pitavastatin results in increased expression of PON1 mRNA]; farnesyl pyrophosphate inhibits the reaction [Simvastatin results in increased expression of PON1 mRNA] CTD PMID:14500290 PMID:15690306 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased activity of RAC1 protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased localization of RAC1 protein]] CTD PMID:18625914 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Rhoa ras homolog family member A multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in decreased activity of RHOA protein]]
farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF affects the localization of RHOA protein]]
CTD PMID:18310456 PMID:18625914 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]] CTD PMID:18310456 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Sele selectin E multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]] CTD PMID:10946302 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF affects the localization of RHOA protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK1 protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK3 protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein]] CTD PMID:18310456 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
geraniol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions EXP geraniol inhibits the reaction [Fructose results in decreased expression of ABCC2 mRNA]; geraniol inhibits the reaction [Fructose results in decreased expression of ABCC2 protein] CTD PMID:31005848 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Acaca acetyl-CoA carboxylase alpha decreases expression ISO geraniol results in decreased expression of ACACA mRNA CTD PMID:26141755 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Ache acetylcholinesterase multiple interactions EXP geraniol inhibits the reaction [Acrylamide results in increased activity of ACHE protein]; geraniol inhibits the reaction [Streptozocin results in increased activity of ACHE protein] CTD PMID:24752916 PMID:25199698 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ACTA2 mRNA] CTD PMID:26695085 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Actl6a actin-like 6A decreases expression ISO geraniol results in decreased expression of ACTL6A mRNA CTD PMID:27683099 NCBI chr 2:115,492,374...115,508,401
Ensembl chr 2:115,492,285...115,508,401
JBrowse link
G Acvr1 activin A receptor type 1 increases expression ISO geraniol results in increased expression of ACVR1 mRNA CTD PMID:27683099 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions EXP geraniol inhibits the reaction [Fructose results in decreased secretion of ADIPOQ protein]; geraniol promotes the reaction [Streptozocin results in decreased expression of ADIPOQ protein] CTD PMID:25679220 PMID:28178614 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Aff4 ALF transcription elongation factor 4 increases expression ISO geraniol results in increased expression of AFF4 mRNA CTD PMID:27683099 NCBI chr10:37,498,825...37,579,751
Ensembl chr10:37,498,825...37,579,751
JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions EXP geraniol inhibits the reaction [Fructose results in increased expression of AGER protein] CTD PMID:25679220 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Ahctf1 AT hook containing transcription factor 1 decreases expression ISO geraniol results in decreased expression of AHCTF1 mRNA CTD PMID:27683099 NCBI chr13:91,481,936...91,536,391
Ensembl chr13:91,481,936...91,536,391
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 increases expression ISO geraniol results in increased expression of AKR1C1 mRNA CTD PMID:30806763 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G Ap5z1 adaptor related protein complex 5 subunit zeta 1 increases expression ISO geraniol results in increased expression of AP5Z1 mRNA CTD PMID:27683099 NCBI chr12:12,093,834...12,109,043
Ensembl chr12:12,093,834...12,108,511
JBrowse link
G Apbb2 amyloid beta precursor protein binding family B member 2 increases expression ISO geraniol results in increased expression of APBB2 mRNA CTD PMID:27683099 NCBI chr14:41,557,918...41,878,622
Ensembl chr14:41,557,972...41,877,495
JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 decreases expression ISO geraniol results in decreased expression of APPL1 mRNA CTD PMID:27683099 NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO geraniol results in increased expression of ATF3 mRNA CTD PMID:27683099 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO geraniol inhibits the reaction [Rotenone results in increased expression of ATF4 protein] CTD PMID:30141137 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf6 activating transcription factor 6 increases expression
multiple interactions
ISO geraniol results in increased expression of ATF6 mRNA
geraniol inhibits the reaction [Rotenone results in increased expression of ATF6 protein]
CTD PMID:27683099 PMID:30141137 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atg12 autophagy related 12 multiple interactions ISO geraniol inhibits the reaction [Rotenone results in decreased expression of ATG12 protein] CTD PMID:30141137 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
JBrowse link
G Atg5 autophagy related 5 multiple interactions ISO geraniol inhibits the reaction [Rotenone results in decreased expression of ATG5 protein] CTD PMID:30141137 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Atg7 autophagy related 7 multiple interactions ISO geraniol inhibits the reaction [Rotenone results in decreased expression of ATG7 protein] CTD PMID:30141137 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO geraniol results in increased expression of BAK1 protein CTD PMID:12530055 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO
EXP
geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of BAX mRNA]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of BAX protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in decreased expression of BAX protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of BAX protein]
geraniol inhibits the reaction [Doxorubicin results in increased expression of BAX mRNA]
geraniol results in increased expression of BAX mRNA; geraniol results in increased expression of BAX protein
CTD PMID:21371438 PMID:22760862 PMID:24768735 PMID:29050341 PMID:29745075 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B decreases expression ISO geraniol results in decreased expression of BAZ1B mRNA CTD PMID:27683099 NCBI chr12:21,431,985...21,489,956
Ensembl chr12:21,431,985...21,490,426
JBrowse link
G Baz2b bromodomain adjacent to zinc finger domain, 2B increases expression ISO geraniol results in increased expression of BAZ2B mRNA CTD PMID:27683099 NCBI chr 3:44,384,282...44,681,619
Ensembl chr 3:44,385,474...44,592,908
JBrowse link
G Bbx BBX high mobility group box domain containing increases expression ISO geraniol results in increased expression of BBX mRNA CTD PMID:27683099 NCBI chr11:50,381,249...50,628,934
Ensembl chr11:50,381,247...50,623,251
JBrowse link
G Bcl11a BCL11 transcription factor A decreases expression ISO geraniol results in decreased expression of BCL11A mRNA CTD PMID:27683099 NCBI chr14:98,029,018...98,124,181
Ensembl chr14:98,030,461...98,124,180
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
increases expression
ISO
EXP
geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of BCL2 mRNA]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of BCL2 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of BCL2 protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of BCL2 protein]
geraniol inhibits the reaction [Doxorubicin results in decreased expression of BCL2 mRNA]
geraniol results in decreased expression of BCL2 mRNA; geraniol results in decreased expression of BCL2 protein
geraniol results in increased expression of BCL2 protein
CTD PMID:21371438 PMID:21445532 PMID:22760862 PMID:24768735 PMID:29050341 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions EXP geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of BCL2L1 protein]; geraniol inhibits the reaction [Isoproterenol results in decreased expression of BCL2L1 mRNA] CTD PMID:26695085 PMID:35608392 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l2 Bcl2-like 2 decreases expression ISO geraniol results in decreased expression of BCL2L2 protein CTD PMID:21371438 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
JBrowse link
G Bcl6 BCL6, transcription repressor increases expression ISO geraniol results in increased expression of BCL6 mRNA CTD PMID:27683099 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 decreases expression ISO geraniol results in decreased expression of BCLAF1 mRNA CTD PMID:27683099 NCBI chr 1:15,088,436...15,117,666
Ensembl chr 1:15,070,894...15,148,832
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BDNF mRNA]; geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BDNF protein] CTD PMID:23943375 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO geraniol results in decreased expression of BIRC5 mRNA CTD PMID:27683099 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 increases expression ISO geraniol results in increased expression of BMAL1 mRNA CTD PMID:27683099 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO geraniol results in increased expression of BMP6 mRNA CTD PMID:27683099 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression ISO geraniol results in increased expression of BNIP3 protein CTD PMID:21371438 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Brca1 BRCA1, DNA repair associated decreases expression ISO geraniol results in decreased expression of BRCA1 mRNA CTD PMID:27683099 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brca2 BRCA2, DNA repair associated decreases expression ISO geraniol results in decreased expression of BRCA2 mRNA CTD PMID:27683099 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Btf3 basic transcription factor 3 decreases expression ISO geraniol results in decreased expression of BTF3 mRNA CTD PMID:27683099 NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression ISO geraniol results in decreased expression of BUB1 mRNA CTD PMID:27683099 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B decreases expression ISO geraniol results in decreased expression of BUB1B mRNA CTD PMID:27683099 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases expression
EXP
ISO
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased cleavage of CASP3 protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of CASP3 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP3 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP3 mRNA]; geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased activity of CASP3 protein]; geraniol inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein]
geraniol results in increased activity of CASP3 protein
geraniol results in increased expression of CASP3 mRNA; geraniol results in increased expression of CASP3 protein
geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CASP3 protein]
geraniol results in increased expression of CASP3 protein modified form
CTD PMID:21371438 PMID:21907755 PMID:22509279 PMID:24875281 PMID:26154255 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions
increases expression
EXP
ISO
geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP8 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP8 mRNA]
geraniol results in increased expression of CASP8 mRNA; geraniol results in increased expression of CASP8 protein
CTD PMID:21907755 PMID:30506710 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
EXP
ISO
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased cleavage of CASP9 protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of CASP9 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP9 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP9 mRNA]; geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased activity of CASP9 protein]; geraniol inhibits the reaction [Doxorubicin results in increased cleavage of CASP9 protein]
geraniol results in increased expression of CASP9 mRNA; geraniol results in increased expression of CASP9 protein
geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CASP9 mRNA]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CASP9 protein]
CTD PMID:21907755 PMID:22509279 PMID:24768735 PMID:26364502 PMID:26695085 More... NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions
decreases activity
increases activity
ISO
EXP
geraniol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CAT protein]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased activity of CAT protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CAT protein]
geraniol results in decreased activity of CAT protein
geraniol results in increased activity of CAT protein
geraniol inhibits the reaction [2-Acetylaminofluorene results in decreased activity of CAT protein]; geraniol inhibits the reaction [ferric nitrilotriacetate results in decreased activity of CAT protein]; geraniol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; geraniol inhibits the reaction [Isoproterenol results in decreased expression of CAT mRNA]; geraniol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]
CTD PMID:21907755 PMID:22760862 PMID:23033690 PMID:23399806 PMID:24752916 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cbfa2t2 CBFA2/RUNX1 partner transcriptional co-repressor 2 increases expression ISO geraniol results in increased expression of CBFA2T2 mRNA CTD PMID:27683099 NCBI chr 3:142,936,945...143,043,205
Ensembl chr 3:142,936,985...143,043,197
JBrowse link
G Cbfb core-binding factor subunit beta decreases expression ISO geraniol results in decreased expression of CBFB mRNA CTD PMID:27683099 NCBI chr19:33,049,162...33,092,752
Ensembl chr19:33,049,172...33,092,751
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases secretion ISO geraniol results in increased secretion of CCL4 protein CTD PMID:30806763 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO geraniol results in decreased expression of CCNA2 mRNA; geraniol results in decreased expression of CCNA2 protein CTD PMID:17138864 PMID:27683099 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO geraniol results in decreased expression of CCNB1 protein CTD PMID:17138864 PMID:21371438 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO geraniol results in decreased expression of CCND1 protein CTD PMID:15450939 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cd86 CD86 molecule increases expression ISO geraniol results in increased expression of CD86 protein CTD PMID:30806763 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdc20 cell division cycle 20 decreases expression ISO geraniol results in decreased expression of CDC20 mRNA CTD PMID:27683099 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdc25a cell division cycle 25A decreases expression ISO geraniol results in decreased expression of CDC25A mRNA CTD PMID:27683099 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO geraniol results in decreased expression of CDC25C mRNA CTD PMID:27683099 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
JBrowse link
G Cdc45 cell division cycle 45 decreases expression ISO geraniol results in decreased expression of CDC45 mRNA CTD PMID:27683099 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
JBrowse link
G Cdc7 cell division cycle 7 decreases expression ISO geraniol results in decreased expression of CDC7 mRNA CTD PMID:27683099 NCBI chr14:2,804,660...2,824,796
Ensembl chr14:2,804,661...2,824,778
JBrowse link
G Cdh1 cadherin 1 multiple interactions EXP geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 protein] CTD PMID:28428697 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO geraniol results in decreased expression of CDK1 protein CTD PMID:21371438 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression
multiple interactions
ISO geraniol results in decreased expression of CDK2 mRNA; geraniol results in decreased expression of CDK2 protein
geraniol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein]; geraniol promotes the reaction [CDKN1B protein binds to and results in decreased activity of CDK2 protein]
CTD PMID:15450939 PMID:17138864 PMID:27683099 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO geraniol results in decreased expression of CDK4 protein CTD PMID:15450939 PMID:21371438 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
increases response to substance
ISO geraniol results in increased expression of CDKN1A protein
geraniol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein]
CDKN1A protein results in increased susceptibility to geraniol
CTD PMID:17138864 PMID:21371438 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression
multiple interactions
increases response to substance
ISO geraniol results in increased expression of CDKN1B protein
geraniol promotes the reaction [CDKN1B protein binds to and results in decreased activity of CDK2 protein]
CDKN1B protein results in increased susceptibility to geraniol
CTD PMID:17138864 PMID:21371438 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C decreases expression ISO geraniol results in decreased expression of CDKN2C mRNA CTD PMID:27683099 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression ISO geraniol results in decreased expression of CDKN3 mRNA CTD PMID:27683099 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 decreases expression ISO geraniol results in decreased expression of CDT1 mRNA CTD PMID:27683099 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO geraniol results in increased expression of CEBPB mRNA CTD PMID:27683099 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma increases expression ISO geraniol results in increased expression of CEBPG mRNA CTD PMID:27683099 NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569
JBrowse link
G Cenpe centromere protein E decreases expression ISO geraniol results in decreased expression of CENPE mRNA CTD PMID:27683099 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
JBrowse link
G Cenpf centromere protein F decreases expression ISO geraniol results in decreased expression of CENPF mRNA CTD PMID:27683099 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
JBrowse link
G Chek1 checkpoint kinase 1 decreases expression ISO geraniol results in decreased expression of CHEK1 mRNA CTD PMID:27683099 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
JBrowse link
G Cit citron rho-interacting serine/threonine kinase decreases expression ISO geraniol results in decreased expression of CIT mRNA CTD PMID:27683099 NCBI chr12:40,603,073...40,764,846
Ensembl chr12:40,605,563...40,763,860
JBrowse link
G Ckm creatine kinase, M-type multiple interactions EXP geraniol inhibits the reaction [Doxorubicin results in increased activity of CKM protein] CTD PMID:34343525 NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720
JBrowse link
G Cnbp CCHC-type zinc finger, nucleic acid binding protein decreases expression ISO geraniol results in decreased expression of CNBP mRNA CTD PMID:27683099 NCBI chr 4:120,302,768...120,311,694
Ensembl chr 4:120,302,771...120,311,637
JBrowse link
G Cnga2 cyclic nucleotide gated channel subunit alpha 2 multiple interactions ISO CNGA2 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein] CTD PMID:29070885 NCBI chr  X:149,696,999...149,715,051
Ensembl chr  X:149,696,997...149,715,051
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA] CTD PMID:26695085 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Cox7c cytochrome c oxidase subunit 7C multiple interactions ISO geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of COX7C mRNA] CTD PMID:24768735 NCBI chr 2:16,841,771...16,843,796
Ensembl chr 2:16,840,837...16,843,760
JBrowse link
G Creb3 cAMP responsive element binding protein 3 increases expression ISO geraniol results in increased expression of CREB3 mRNA CTD PMID:27683099 NCBI chr 5:57,817,865...57,823,233
Ensembl chr 5:57,817,832...57,824,390
JBrowse link
G Creb3l2 cAMP responsive element binding protein 3-like 2 increases expression ISO geraniol results in increased expression of CREB3L2 mRNA CTD PMID:27683099 NCBI chr 4:65,907,570...66,112,078
Ensembl chr 4:65,907,655...66,023,763
JBrowse link
G Crp C-reactive protein multiple interactions EXP geraniol inhibits the reaction [Isoproterenol results in increased expression of CRP protein] CTD PMID:35608392 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions EXP geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CTNNB1 mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 protein] CTD PMID:26165751 PMID:28428697 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctsd cathepsin D multiple interactions EXP geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased activity of CTSD protein] CTD PMID:23499697 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cyb5a cytochrome b5 type A multiple interactions EXP geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased activity of CYB5A protein] CTD PMID:23499697 NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions ISO geraniol inhibits the reaction [Dietary Fats results in increased expression of CYBB protein]
geraniol inhibits the reaction [Palmitic Acid results in increased expression of CYBB protein]
CTD PMID:27107694 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cyc1 cytochrome c-1 multiple interactions ISO geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CYC1 protein] CTD PMID:24768735 NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases metabolic processing
ISO [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol; [CYP1A1 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [CYP1A1 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite CTD PMID:18824010 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol CTD PMID:18824010 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
increases metabolic processing
ISO [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol; [CYP2B6 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; geraniol inhibits the reaction [CYP2B6 protein results in increased hydrolysis of Bupropion] CTD PMID:18611395 PMID:18824010 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP
ISO
geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CYP2E1 protein]
[[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol
CTD PMID:18824010 PMID:26695085 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases metabolic processing
multiple interactions
ISO CYP3A5 protein results in increased metabolism of geraniol
[[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol; [CYP3A5 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [CYP3A5 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite
CTD PMID:18824010 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Dbf4 DBF4-CDC7 kinase regulatory subunit decreases expression ISO geraniol results in decreased expression of DBF4 mRNA CTD PMID:27683099 NCBI chr 4:25,676,570...25,701,152
Ensembl chr 4:25,676,634...25,701,066
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO geraniol results in increased expression of DDIT3 mRNA
geraniol inhibits the reaction [Rotenone results in increased expression of DDIT3 protein]
CTD PMID:27683099 PMID:30141137 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dek DEK proto-oncogene decreases expression ISO geraniol results in decreased expression of DEK mRNA CTD PMID:27683099 NCBI chr17:17,580,804...17,602,825
Ensembl chr17:17,580,843...17,602,808
JBrowse link
G Dmtf1 cyclin D binding myb-like transcription factor 1 increases expression ISO geraniol results in increased expression of DMTF1 mRNA CTD PMID:27683099 NCBI chr 4:24,909,937...24,950,786
Ensembl chr 4:24,910,534...24,950,967
JBrowse link
G Dnajc1 DnaJ heat shock protein family (Hsp40) member C1 increases expression ISO geraniol results in increased expression of DNAJC1 mRNA CTD PMID:27683099 NCBI chr17:80,955,209...81,112,025
Ensembl chr17:80,955,237...81,111,988
JBrowse link
G Dr1 down-regulator of transcription 1 decreases expression ISO geraniol results in decreased expression of DR1 mRNA CTD PMID:27683099 NCBI chr14:1,458,223...1,469,578
Ensembl chr14:1,458,223...1,469,638
JBrowse link
G Dtymk deoxythymidylate kinase decreases expression ISO geraniol results in decreased expression of DTYMK mRNA CTD PMID:27683099 NCBI chr 9:94,315,552...94,324,386
Ensembl chr 9:94,315,552...94,324,870
JBrowse link
G E2f1 E2F transcription factor 1 decreases expression ISO geraniol results in decreased expression of E2F1 mRNA CTD PMID:27683099 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
JBrowse link
G E2f8 E2F transcription factor 8 decreases expression ISO geraniol results in decreased expression of E2F8 mRNA; geraniol results in decreased expression of E2F8 protein CTD PMID:27683099 NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098
JBrowse link
G Ehf ets homologous factor decreases expression ISO geraniol results in decreased expression of EHF mRNA CTD PMID:27683099 NCBI chr 3:89,639,845...89,680,061
Ensembl chr 3:89,641,833...89,679,997
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions ISO geraniol inhibits the reaction [Rotenone results in increased expression of EIF2AK3 protein] CTD PMID:30141137 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions ISO geraniol inhibits the reaction [Rotenone results in increased expression of EIF2S1 protein] CTD PMID:30141137 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Elavl2 ELAV like RNA binding protein 2 decreases expression ISO geraniol results in decreased expression of ELAVL2 mRNA CTD PMID:27683099 NCBI chr 5:105,960,872...106,086,463
Ensembl chr 5:105,960,875...106,109,097
JBrowse link
G Elf1 E74 like ETS transcription factor 1 increases expression ISO geraniol results in increased expression of ELF1 mRNA CTD PMID:27683099 NCBI chr15:54,890,644...54,986,721
Ensembl chr15:54,865,616...54,986,699
JBrowse link
G Elk4 ETS transcription factor ELK4 increases expression ISO geraniol results in increased expression of ELK4 mRNA CTD PMID:27683099 NCBI chr13:43,451,130...43,475,035
Ensembl chr13:43,435,843...43,475,035
JBrowse link
G Erc1 ELKS/RAB6-interacting/CAST family member 1 increases expression ISO geraniol results in increased expression of ERC1 mRNA CTD PMID:27683099 NCBI chr 4:152,763,664...153,055,724
Ensembl chr 4:152,767,419...153,055,639
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO geraniol inhibits the reaction [Rotenone results in increased expression of ERN1 protein] CTD PMID:30141137 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Espl1 extra spindle pole bodies like 1, separase decreases expression ISO geraniol results in decreased expression of ESPL1 mRNA CTD PMID:27683099 NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984
JBrowse link
G Esr1 estrogen receptor 1 affects binding
multiple interactions
ISO geraniol binds to ESR1 protein
geraniol inhibits the reaction [Estradiol binds to ESR1 protein]
CTD PMID:12495555 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 affects binding
multiple interactions
ISO geraniol binds to ESR2 protein
geraniol inhibits the reaction [Estradiol binds to ESR2 protein]
CTD PMID:12495555 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor increases expression ISO geraniol results in increased expression of ETS2 mRNA CTD PMID:27683099 NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319
JBrowse link
G Etv1 ETS variant transcription factor 1 decreases expression ISO geraniol results in decreased expression of ETV1 mRNA CTD PMID:27683099 NCBI chr 6:55,590,149...55,681,784
Ensembl chr 6:55,590,234...55,681,775
JBrowse link
G Ewsr1 EWS RNA-binding protein 1 decreases expression ISO geraniol results in decreased expression of EWSR1 mRNA CTD PMID:27683099 NCBI chr14:79,965,365...79,994,108
Ensembl chr14:79,965,368...79,994,544
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit decreases expression ISO geraniol results in decreased expression of EZH2 mRNA CTD PMID:27683099 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression ISO geraniol results in increased expression of FABP4 mRNA CTD PMID:30806763 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Fads1 fatty acid desaturase 1 multiple interactions
decreases activity
ISO [geraniol results in decreased activity of FADS1 protein] which results in decreased chemical synthesis of Arachidonic Acid; [geraniol results in decreased activity of FADS1 protein] which results in decreased metabolism of 8,11,14-Eicosatrienoic Acid CTD PMID:16462894 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
JBrowse link
G Fancg FA complementation group G decreases expression ISO geraniol results in decreased expression of FANCG mRNA CTD PMID:27683099 NCBI chr 5:57,230,287...57,240,067
Ensembl chr 5:57,231,685...57,240,029
JBrowse link
G Fasn fatty acid synthase multiple interactions EXP geraniol promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of FASN mRNA] CTD PMID:26695085 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbxo5 F-box protein 5 decreases expression ISO geraniol results in decreased expression of FBXO5 mRNA CTD PMID:27683099 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO geraniol results in increased expression of FOS mRNA CTD PMID:27683099 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit decreases expression ISO geraniol results in decreased expression of FOSL1 mRNA CTD PMID:27683099 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit increases expression ISO geraniol results in increased expression of FOSL2 mRNA CTD PMID:27683099 NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034
JBrowse link
G Foxa2 forkhead box A2 decreases expression ISO geraniol results in decreased expression of FOXA2 mRNA CTD PMID:27683099 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
JBrowse link
G Foxj3 forkhead box J3 increases expression ISO geraniol results in increased expression of FOXJ3 mRNA CTD PMID:27683099 NCBI chr 5:133,140,344...133,228,489
Ensembl chr 5:133,140,884...133,228,489
JBrowse link
G Foxm1 forkhead box M1 decreases expression ISO geraniol results in decreased expression of FOXM1 mRNA CTD PMID:27683099 NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684
JBrowse link
G Foxo4 forkhead box O4 increases expression ISO geraniol results in increased expression of FOXO4 mRNA CTD PMID:27683099 NCBI chr  X:66,385,241...66,392,115
Ensembl chr  X:66,385,558...66,392,115
JBrowse link
G Fst follistatin increases expression ISO geraniol results in increased expression of FST mRNA CTD PMID:27683099 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
JBrowse link
G Fubp1 far upstream element binding protein 1 decreases expression ISO geraniol results in decreased expression of FUBP1 mRNA CTD PMID:27683099 NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions ISO
EXP
geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of G6PD protein]
geraniol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]
CTD PMID:23399806 PMID:28330423 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gatad1 GATA zinc finger domain containing 1 increases expression ISO geraniol results in increased expression of GATAD1 mRNA CTD PMID:27683099 NCBI chr 4:30,507,530...30,519,107
Ensembl chr 4:30,507,538...30,519,107
JBrowse link
G Gbx2 gastrulation brain homeobox 2 decreases expression ISO geraniol results in decreased expression of GBX2 mRNA CTD PMID:27683099 NCBI chr 9:90,509,633...90,512,212
Ensembl chr 9:90,509,633...90,512,212
JBrowse link
G Gcg glucagon multiple interactions
increases secretion
ISO 9-(tetrahydro-2-furyl)-adenine inhibits the reaction [geraniol results in increased secretion of GCG protein]; CNGA2 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein]; GNAL mRNA promotes the reaction [geraniol results in increased secretion of GCG protein]; OR1A1 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein]; OR1G1 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein] CTD PMID:29070885 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929
JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions ISO geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of GDNF mRNA]; geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of GDNF protein] CTD PMID:23943375 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Gmnn geminin, DNA replication inhibitor decreases expression ISO geraniol results in decreased expression of GMNN mRNA CTD PMID:27683099 NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054
JBrowse link
G Gna15 G protein subunit alpha 15 increases response to substance
multiple interactions
ISO GNA15 protein results in increased susceptibility to geraniol
[GNA15 protein results in increased susceptibility to geraniol] which results in increased activity of OR1A1B protein
CTD PMID:15598656 NCBI chr 7:8,184,632...8,205,508
Ensembl chr 7:8,184,861...8,205,508
JBrowse link
G Gnal G protein subunit alpha L increases response to substance
multiple interactions
ISO GNAL protein results in increased susceptibility to geraniol
[GNAL protein results in increased susceptibility to geraniol] which results in increased activity of OR1A1B protein; GNAL mRNA promotes the reaction [geraniol results in increased secretion of GCG protein]
CTD PMID:15598656 PMID:29070885 NCBI chr18:60,622,311...60,762,599
Ensembl chr18:60,622,311...60,762,599
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions EXP geraniol inhibits the reaction [Doxorubicin results in increased activity of GOT1 protein] CTD PMID:34343525 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP geraniol inhibits the reaction [Doxorubicin results in increased activity of GPT protein] CTD PMID:34343525 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of GPX1 mRNA] CTD PMID:22509279 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein] CTD PMID:26165751 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
ISO
EXP
geraniol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of GSR protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GSR protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of GSR protein]
geraniol results in decreased activity of GSR protein
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased activity of GSR protein]; [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of GSR mRNA]; geraniol inhibits the reaction [2-Acetylaminofluorene results in decreased activity of GSR protein]; geraniol inhibits the reaction [Streptozocin affects the activity of GSR protein]
CTD PMID:22509279 PMID:22760862 PMID:23033690 PMID:23399806 PMID:24752916 More... NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions EXP geraniol inhibits the reaction [Diethylnitrosamine results in increased expression of GSTP1 protein] CTD PMID:27046949 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gtf2b general transcription factor IIB increases expression ISO geraniol results in increased expression of GTF2B mRNA CTD PMID:27683099 NCBI chr 2:231,767,317...231,785,626
Ensembl chr 2:231,767,238...231,785,651
JBrowse link
G Gtf2h1 general transcription factor IIH subunit 1 increases expression ISO geraniol results in increased expression of GTF2H1 mRNA CTD PMID:27683099 NCBI chr 1:97,321,417...97,349,455
Ensembl chr 1:97,321,394...97,349,455
JBrowse link
G Gtf2ird1 GTF2I repeat domain containing 1 increases expression ISO geraniol results in increased expression of GTF2IRD1 mRNA CTD PMID:27683099 NCBI chr12:22,254,113...22,361,052
Ensembl chr12:22,254,221...22,361,040
JBrowse link
G Gtf3a general transcription factor III A decreases expression ISO geraniol results in decreased expression of GTF3A mRNA CTD PMID:27683099 NCBI chr12:8,136,746...8,144,690
Ensembl chr12:8,136,747...8,144,690
JBrowse link
G Gtf3c1 general transcription factor IIIC subunit 1 increases expression ISO geraniol results in increased expression of GTF3C1 mRNA CTD PMID:27683099 NCBI chr 1:180,203,995...180,270,201
Ensembl chr 1:180,203,995...180,270,201
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions EXP geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of HAVCR1 mRNA]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of HAVCR1 protein] CTD PMID:21907755 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Hbb hemoglobin subunit beta multiple interactions EXP geraniol inhibits the reaction [Fructose promotes the reaction [Glucose binds to HBB protein]] CTD PMID:25679220 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
JBrowse link
G Hbp1 HMG-box transcription factor 1 increases expression ISO geraniol results in increased expression of HBP1 mRNA CTD PMID:27683099 NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787
JBrowse link
G Hivep1 HIVEP zinc finger 1 increases expression ISO geraniol results in increased expression of HIVEP1 mRNA CTD PMID:27683099 NCBI chr17:22,585,016...22,714,517
Ensembl chr17:22,585,016...22,711,956
JBrowse link
G Hlf HLF transcription factor, PAR bZIP family member decreases expression ISO geraniol results in decreased expression of HLF mRNA CTD PMID:27683099 NCBI chr10:75,154,244...75,211,884
Ensembl chr10:75,154,507...75,211,935
JBrowse link
G Hmbox1 homeobox containing 1 increases expression ISO geraniol results in increased expression of HMBOX1 mRNA CTD PMID:27683099 NCBI chr15:39,067,805...39,200,633
Ensembl chr15:39,067,804...39,200,323
JBrowse link
G Hmg20b high mobility group 20 B decreases expression ISO geraniol results in decreased expression of HMG20B mRNA CTD PMID:27683099 NCBI chr 7:8,368,934...8,373,650
Ensembl chr 7:8,368,990...8,373,640
JBrowse link
G Hmgb2 high mobility group box 2 decreases expression ISO geraniol results in decreased expression of HMGB2 mRNA CTD PMID:27683099 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
JBrowse link
G Hmgb3 high mobility group box 3 decreases expression ISO geraniol results in decreased expression of HMGB3 mRNA CTD PMID:27683099 NCBI chr  X:149,296,303...149,301,290
Ensembl chr  X:149,296,375...149,301,292
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression
decreases expression
affects expression
decreases activity
ISO geraniol results in increased expression of HMGCR mRNA
geraniol results in decreased expression of HMGCR protein
geraniol affects the expression of HMGCR mRNA
geraniol results in decreased activity of HMGCR protein
CTD PMID:12477733 PMID:15450939 PMID:16462894 PMID:23668785 PMID:24875281 More... NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgxb3 HMG-box containing 3 increases expression ISO geraniol results in increased expression of HMGXB3 mRNA CTD PMID:27683099 NCBI chr18:54,590,558...54,638,050
Ensembl chr18:54,590,560...54,638,155
JBrowse link
G Hmgxb4 HMG-box containing 4 decreases expression ISO geraniol results in decreased expression of HMGXB4 mRNA CTD PMID:27683099 NCBI chr19:13,364,741...13,403,563
Ensembl chr19:13,364,807...13,403,563
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO
EXP
geraniol results in increased expression of HMOX1 mRNA
geraniol promotes the reaction [Doxorubicin results in increased expression of HMOX1 mRNA]; geraniol promotes the reaction [Doxorubicin results in increased expression of HMOX1 protein]
geraniol results in increased expression of HMOX1 protein
CTD PMID:20713136 PMID:28334550 PMID:30806763 PMID:34343525 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnrnpab heterogeneous nuclear ribonucleoprotein A/B decreases expression ISO geraniol results in decreased expression of HNRNPAB mRNA CTD PMID:27683099 NCBI chr10:35,857,040...35,862,935
Ensembl chr10:35,857,041...35,863,344
JBrowse link
G Hoxa5 homeo box A5 increases expression ISO geraniol results in increased expression of HOXA5 mRNA CTD PMID:27683099 NCBI chr 4:81,302,341...81,306,234
Ensembl chr 4:81,302,353...81,306,234
JBrowse link
G Hoxb13 homeo box B13 decreases expression ISO geraniol results in decreased expression of HOXB13 mRNA CTD PMID:27683099 NCBI chr10:81,160,498...81,162,777
Ensembl chr10:81,160,498...81,162,777
JBrowse link
G Hoxc6 homeo box C6 increases expression ISO geraniol results in increased expression of HOXC6 mRNA CTD PMID:27683099 NCBI chr 7:134,138,017...134,148,899
Ensembl chr 7:134,135,502...134,148,392
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with geraniol] affects the localization of HRAS protein CTD PMID:22760862 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 decreases expression ISO geraniol results in decreased expression of HSPA2 mRNA CTD PMID:27683099 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A decreases activity ISO geraniol results in decreased activity of HTR3A protein CTD PMID:26456648 NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO
EXP
geraniol inhibits the reaction [Dietary Fats results in increased expression of ICAM1 protein]
geraniol inhibits the reaction [Palmitic Acid results in increased expression of ICAM1 protein]
geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]
CTD PMID:26165751 PMID:27107694 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Id1 inhibitor of DNA binding 1 increases expression ISO geraniol results in increased expression of ID1 mRNA CTD PMID:27683099 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Id3 inhibitor of DNA binding 3 increases expression ISO geraniol results in increased expression of ID3 mRNA CTD PMID:27683099 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
JBrowse link
G Ifng interferon gamma multiple interactions ISO geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IFNG protein] CTD PMID:26973525 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il10 interleukin 10 increases expression
multiple interactions
ISO geraniol results in increased expression of IL10 protein
geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL10 protein]
CTD PMID:24934659 PMID:26973525 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il16 interleukin 16 increases secretion ISO geraniol results in increased secretion of IL16 protein CTD PMID:30806763 NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130
JBrowse link
G Il17a interleukin 17A multiple interactions ISO geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL17A protein] CTD PMID:26973525 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il18 interleukin 18 multiple interactions ISO
EXP
geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]; geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]]; geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]]; geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]]
geraniol inhibits the reaction [Doxorubicin results in increased expression of IL18 protein]
CTD PMID:21430599 PMID:34343525 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO geraniol results in increased expression of IL1A protein CTD PMID:19878710 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of IL1B protein]; geraniol inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]; geraniol inhibits the reaction [Fructose results in increased expression of IL1B protein]; geraniol inhibits the reaction [Fructose results in increased secretion of IL1B protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]
2-chloro-5-nitrobenzanilide inhibits the reaction [geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of IL1B protein]]; geraniol inhibits the reaction [[Alendronate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]; geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of IL1B protein]; geraniol inhibits the reaction [[Pamidronate co-treated with Acetylmuramyl-Alanyl-Isoglutamine] results in increased secretion of IL1B protein]; geraniol inhibits the reaction [[Pamidronate co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]; geraniol inhibits the reaction [ovalbumin-alum results in increased expression of and results in increased secretion of IL1B protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]]; geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]]; geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]]
geraniol inhibits the reaction [[MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased expression of IL1B protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL1B protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]
CTD PMID:20304105 PMID:21282739 PMID:21430599 PMID:23399806 PMID:25679220 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1r2 interleukin 1 receptor type 2 increases expression ISO geraniol results in increased expression of IL1R2 mRNA CTD PMID:30806763 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO
EXP
geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; geraniol inhibits the reaction [Dietary Fats results in increased expression of IL6 protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]
geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL6 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]
geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 protein]; geraniol inhibits the reaction [Fructose results in increased expression of IL6 protein]; geraniol inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]
geraniol results in increased expression of IL6 mRNA
CTD PMID:23399806 PMID:26190278 PMID:26695085 PMID:26973525 PMID:27107694 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il7r interleukin 7 receptor increases expression ISO geraniol results in increased expression of IL7R mRNA CTD PMID:20713136 NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757
JBrowse link
G Ilf2 interleukin enhancer binding factor 2 decreases expression ISO geraniol results in decreased expression of ILF2 mRNA CTD PMID:27683099 NCBI chr 2:175,952,174...175,971,191
Ensembl chr 2:175,952,186...175,971,337
JBrowse link
G Ins1 insulin 1 increases secretion
multiple interactions
ISO
EXP
geraniol results in increased secretion of INS1 protein
geraniol inhibits the reaction [Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein]
CTD PMID:28330423 PMID:29070885 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Irf1 interferon regulatory factor 1 increases expression ISO geraniol results in increased expression of IRF1 mRNA CTD PMID:27683099 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Irf6 interferon regulatory factor 6 increases expression ISO geraniol results in increased expression of IRF6 mRNA CTD PMID:27683099 NCBI chr13:104,672,179...104,691,386
Ensembl chr13:104,672,179...104,691,386
JBrowse link
G Irf7 interferon regulatory factor 7 increases expression ISO geraniol results in increased expression of IRF7 mRNA CTD PMID:27683099 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
JBrowse link
G Irf9 interferon regulatory factor 9 increases expression ISO geraniol results in increased expression of IRF9 mRNA CTD PMID:27683099 NCBI chr15:29,095,474...29,101,924
Ensembl chr15:29,095,789...29,101,236
JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 increases expression ISO geraniol results in increased expression of JARID2 mRNA CTD PMID:27683099 NCBI chr17:19,777,487...19,957,696
Ensembl chr17:19,777,266...19,955,690
JBrowse link
G Jmjd1c jumonji domain containing 1C increases expression ISO geraniol results in increased expression of JMJD1C mRNA CTD PMID:27683099 NCBI chr20:21,332,147...21,494,220
Ensembl chr20:21,332,147...21,463,122
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO geraniol results in increased expression of JUN mRNA CTD PMID:27683099 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit increases expression ISO geraniol results in increased expression of JUNB mRNA CTD PMID:27683099 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit increases expression ISO geraniol results in increased expression of JUND mRNA CTD PMID:27683099 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
JBrowse link
G Kdr kinase insert domain receptor decreases expression ISO geraniol results in decreased expression of KDR protein CTD PMID:26154255 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Khdrbs1 KH RNA binding domain containing, signal transduction associated 1 decreases expression ISO geraniol results in decreased expression of KHDRBS1 mRNA CTD PMID:27683099 NCBI chr 5:142,051,844...142,089,175
Ensembl chr 5:142,063,570...142,089,180
JBrowse link
G Kif11 kinesin family member 11 decreases expression ISO geraniol results in decreased expression of KIF11 mRNA CTD PMID:27683099 NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
JBrowse link
G Kif15 kinesin family member 15 decreases expression ISO geraniol results in decreased expression of KIF15 mRNA CTD PMID:27683099 NCBI chr 8:122,601,888...122,672,750
Ensembl chr 8:122,601,897...122,672,750
JBrowse link
G Kif22 kinesin family member 22 decreases expression ISO geraniol results in decreased expression of KIF22 mRNA CTD PMID:27683099 NCBI chr 1:181,635,347...181,650,351
Ensembl chr 1:181,635,183...181,650,401
JBrowse link
G Kif23 kinesin family member 23 decreases expression ISO geraniol results in decreased expression of KIF23 mRNA CTD PMID:27683099 NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
JBrowse link
G Kif2c kinesin family member 2C decreases expression ISO geraniol results in decreased expression of KIF2C mRNA CTD PMID:27683099 NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637
JBrowse link
G Klf11 KLF transcription factor 11 increases expression ISO geraniol results in increased expression of KLF11 mRNA CTD PMID:27683099 NCBI chr 6:41,285,699...41,297,548
Ensembl chr 6:41,285,842...41,297,550
JBrowse link
G Klf13 KLF transcription factor 13 increases expression ISO geraniol results in increased expression of KLF13 mRNA CTD PMID:27683099 NCBI chr 1:117,505,857...117,536,626
Ensembl chr 1:117,503,602...117,551,227
JBrowse link
G Klf3 KLF transcription factor 3 increases expression ISO geraniol results in increased expression of KLF3 mRNA CTD PMID:27683099 NCBI chr14:43,474,767...43,505,801
Ensembl chr14:43,474,767...43,497,209
JBrowse link
G Klf4 KLF transcription factor 4 increases expression ISO geraniol results in increased expression of KLF4 mRNA CTD PMID:27683099 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Klf5 KLF transcription factor 5 increases expression ISO geraniol results in increased expression of KLF5 mRNA CTD PMID:27683099 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
JBrowse link
G Klf6 KLF transcription factor 6 increases expression ISO geraniol results in increased expression of KLF6 mRNA CTD PMID:27683099 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
JBrowse link
G Klf7 KLF transcription factor 7 increases expression ISO geraniol results in increased expression of KLF7 mRNA CTD PMID:27683099 NCBI chr 9:65,433,683...65,526,372
Ensembl chr 9:65,437,167...65,526,261
JBrowse link
G Kntc1 kinetochore associated 1 decreases expression ISO geraniol results in decreased expression of KNTC1 mRNA CTD PMID:27683099 NCBI chr12:32,769,020...32,839,617
Ensembl chr12:32,769,020...32,839,561
JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions EXP geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of KRAS mRNA] CTD PMID:28428697 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO geraniol results in increased expression of LDLR mRNA CTD PMID:26141755 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lif LIF, interleukin 6 family cytokine decreases expression ISO geraniol results in decreased expression of LIF protein CTD PMID:19878710 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Lztfl1 leucine zipper transcription factor-like 1 increases expression ISO geraniol results in increased expression of LZTFL1 mRNA CTD PMID:27683099 NCBI chr 8:123,344,085...123,360,245
Ensembl chr 8:123,344,925...123,360,192
JBrowse link
G Lztr1 leucine zipper like post translational regulator 1 increases expression ISO geraniol results in increased expression of LZTR1 mRNA CTD PMID:27683099 NCBI chr11:83,487,717...83,503,896
Ensembl chr11:83,487,717...83,503,633
JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 decreases expression ISO geraniol results in decreased expression of MAD2L1 mRNA CTD PMID:27683099 NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO geraniol results in increased expression of MAFF mRNA CTD PMID:27683099 NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Mafg MAF bZIP transcription factor G increases expression ISO geraniol results in increased expression of MAFG mRNA CTD PMID:27683099 NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026
JBrowse link
G Maob monoamine oxidase B multiple interactions ISO geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of MAOB protein] CTD PMID:24103762 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions EXP geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of MAP2K1 mRNA] CTD PMID:28428697 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation
ISO geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK1 protein]
geraniol results in decreased phosphorylation of MAPK1 protein
CTD PMID:12388655 PMID:22760862 PMID:26154255 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation
ISO
EXP
geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK3 protein]
geraniol inhibits the reaction [Isoproterenol results in increased expression of MAPK3 mRNA]; geraniol inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]
geraniol results in decreased phosphorylation of MAPK3 protein
CTD PMID:12388655 PMID:22760862 PMID:26154255 PMID:35608392 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP geraniol inhibits the reaction [Isoproterenol results in increased expression of MAPK8 mRNA]; geraniol inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein] CTD PMID:35608392 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 decreases expression ISO geraniol results in decreased expression of MCM2 mRNA CTD PMID:27683099 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
JBrowse link
G Mef2a myocyte enhancer factor 2a increases expression ISO geraniol results in increased expression of MEF2A mRNA CTD PMID:27683099 NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948
JBrowse link
G Men1 menin 1 increases expression ISO geraniol results in increased expression of MEN1 mRNA CTD PMID:27683099 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO geraniol results in decreased expression of MKI67 mRNA
geraniol results in decreased expression of MKI67 protein
CTD PMID:26154255 PMID:27683099 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP geraniol inhibits the reaction [Isoproterenol results in increased expression of MMP2 mRNA] CTD PMID:35608392 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression ISO geraniol results in increased expression of MMP3 mRNA CTD PMID:30806763 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP geraniol inhibits the reaction [Isoproterenol results in increased expression of MMP9 mRNA] CTD PMID:35608392 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mnt MAX network transcriptional repressor increases expression ISO geraniol results in increased expression of MNT mRNA CTD PMID:27683099 NCBI chr10:59,699,208...59,714,848
Ensembl chr10:59,699,585...59,714,835
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO
EXP
2-chloro-5-nitrobenzanilide inhibits the reaction [geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased activity of MPO protein]]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased activity of MPO protein]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of MPO protein]
geraniol inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of MPO protein]; geraniol inhibits the reaction [Cysteamine results in increased expression of MPO protein]; geraniol inhibits the reaction [Ethanol results in increased expression of MPO protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]
CTD PMID:24337826 PMID:26165751 PMID:26190278 PMID:30550845 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases activity
multiple interactions
ISO geraniol results in decreased activity of MTOR protein
geraniol inhibits the reaction [Rotenone results in increased phosphorylation of MTOR protein]
CTD PMID:22200837 PMID:30141137 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Mvk mevalonate kinase multiple interactions ISO geraniol inhibits the reaction [[MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased expression of IL1B protein]; geraniol inhibits the reaction [MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] CTD PMID:20304105 NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882
JBrowse link
G Mxd1 max dimerization protein 1 increases expression ISO geraniol results in increased expression of MXD1 mRNA CTD PMID:27683099 NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751
JBrowse link
G Mxd4 Max dimerization protein 4 increases expression ISO geraniol results in increased expression of MXD4 mRNA CTD PMID:27683099 NCBI chr14:76,562,105...76,576,224
Ensembl chr14:76,561,774...76,576,221
JBrowse link
G Mxi1 MAX interactor 1, dimerization protein increases expression ISO geraniol results in increased expression of MXI1 mRNA CTD PMID:27683099 NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:252,323,303...252,383,681
JBrowse link
G Myb MYB proto-oncogene, transcription factor decreases expression ISO geraniol results in decreased expression of MYB mRNA CTD PMID:27683099 NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057
JBrowse link
G Mybl1 MYB proto-oncogene like 1 decreases expression ISO geraniol results in decreased expression of MYBL1 mRNA CTD PMID:27683099 NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183
JBrowse link
G Mybl2 MYB proto-oncogene like 2 decreases expression ISO geraniol results in decreased expression of MYBL2 mRNA CTD PMID:27683099 NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708
JBrowse link
G Myo6 myosin VI increases expression ISO geraniol results in increased expression of MYO6 mRNA CTD PMID:27683099 NCBI chr 8:81,087,157...81,242,022
Ensembl chr 8:81,087,139...81,239,292
JBrowse link
G Nasp nuclear autoantigenic sperm protein decreases expression ISO geraniol results in decreased expression of NASP mRNA CTD PMID:27683099 NCBI chr 5:130,057,363...130,083,003
Ensembl chr 5:130,057,363...130,082,928
JBrowse link
G Ncaph non-SMC condensin I complex, subunit H decreases expression ISO geraniol results in decreased expression of NCAPH mRNA CTD PMID:27683099 NCBI chr 3:114,371,937...114,399,178
Ensembl chr 3:114,371,941...114,399,180
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 increases expression ISO geraniol results in increased expression of NCOR1 mRNA CTD PMID:27683099 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
JBrowse link
G Ndp norrin cystine knot growth factor NDP decreases expression ISO geraniol results in decreased expression of NDP mRNA CTD PMID:27683099 NCBI chr  X:5,796,487...5,820,934
Ensembl chr  X:5,796,487...5,820,934
JBrowse link
G Nek2 NIMA-related kinase 2 decreases expression ISO geraniol results in decreased expression of NEK2 mRNA CTD PMID:27683099 NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051
JBrowse link
G Nfat5 nuclear factor of activated T-cells 5 increases expression ISO geraniol results in increased expression of NFAT5 mRNA CTD PMID:27683099 NCBI chr19:35,199,737...35,286,675
Ensembl chr19:35,199,016...35,286,675
JBrowse link
G Nfe2l1 NFE2 like bZIP transcription factor 1 increases expression ISO geraniol results in increased expression of NFE2L1 mRNA CTD PMID:27683099 NCBI chr10:81,796,055...81,812,926
Ensembl chr10:81,800,366...81,832,318
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions
ISO
EXP
geraniol results in increased expression of NFE2L2 mRNA
geraniol promotes the reaction [Doxorubicin results in increased expression of NFE2L2 mRNA]; geraniol promotes the reaction [Doxorubicin results in increased expression of NFE2L2 protein]
geraniol results in increased expression of NFE2L2 protein
CTD PMID:27683099 PMID:28334550 PMID:34343525 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated increases expression ISO geraniol results in increased expression of NFIL3 mRNA CTD PMID:27683099 NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions EXP geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of NFKB1 mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NFKB1 protein] CTD PMID:21907755 PMID:26165751 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO
EXP
geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of NFKBIA mRNA]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of NFKBIA protein modified form]; geraniol inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKBIA protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NFKBIA protein modified form]; geraniol inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]
geraniol inhibits the reaction [Doxorubicin results in increased expression of and results in increased phosphorylation of NFKBIA protein]
CTD PMID:20506077 PMID:26190278 PMID:29050341 PMID:30550845 PMID:34343525 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfyb nuclear transcription factor Y subunit beta decreases expression ISO geraniol results in decreased expression of NFYB mRNA CTD PMID:27683099 NCBI chr 7:20,964,988...20,980,569
Ensembl chr 7:20,964,993...20,980,565
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression
EXP
ISO
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased expression of NOS2 mRNA]; [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased expression of NOS2 protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of NOS2 protein]; geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of NOS2 protein]; geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of NOS2 protein]
geraniol results in decreased expression of NOS2 mRNA; geraniol results in decreased expression of NOS2 protein
geraniol inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 protein]
CTD PMID:20506077 PMID:22509279 PMID:26190278 PMID:26364502 PMID:26695085 More... NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions ISO geraniol inhibits the reaction [Palmitic Acid results in increased expression of NOX1 protein] CTD PMID:27107694 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236
JBrowse link
G Npm1 nucleophosmin 1 decreases expression ISO geraniol results in decreased expression of NPM1 mRNA CTD PMID:27683099 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in decreased activity of NQO1 protein]; geraniol inhibits the reaction [Doxorubicin results in decreased expression of NQO1 protein] CTD PMID:23499697 PMID:34343525 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 increases expression ISO geraniol results in increased expression of NR1D1 mRNA CTD PMID:27683099 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 increases expression ISO geraniol results in increased expression of NR1D2 mRNA CTD PMID:27683099 NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553
JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 decreases expression ISO geraniol results in decreased expression of NR2F1 mRNA CTD PMID:27683099 NCBI chr 2:8,040,375...8,050,123
Ensembl chr 2:8,040,377...8,050,123
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases expression ISO geraniol results in increased expression of NR3C1 mRNA CTD PMID:27683099 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases expression ISO geraniol results in increased expression of NR4A2 mRNA CTD PMID:27683099 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 decreases expression ISO geraniol results in decreased expression of NSD2 mRNA CTD PMID:27683099 NCBI chr14:76,833,179...76,911,304
Ensembl chr14:76,835,637...76,913,641
JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 decreases expression ISO geraniol results in decreased expression of NUSAP1 mRNA CTD PMID:27683099 NCBI chr 3:106,603,273...106,633,428
Ensembl chr 3:106,603,289...106,633,624
JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions
decreases activity
ISO geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 protein]
geraniol results in decreased activity of ODC1 protein
CTD PMID:11408542 PMID:22760862 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase multiple interactions EXP [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased expression of OGG1 protein] CTD PMID:22509279 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Or1a1 olfactory receptor family 1 subfamily A member 1 multiple interactions ISO [GNA15 protein results in increased susceptibility to geraniol] which results in increased activity of OR1A1B protein; [GNAL protein results in increased susceptibility to geraniol] which results in increased activity of OR1A1B protein; OR1A1 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein] CTD PMID:15598656 PMID:29070885 NCBI chr10:59,058,941...59,059,879
Ensembl chr10:59,052,828...59,060,676
JBrowse link
G Or1ad5 olfactory receptor family 1 subfamily AD member 5 multiple interactions ISO OR1G1 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein] CTD PMID:29070885 NCBI chr10:35,307,662...35,308,573
Ensembl chr10:35,304,703...35,308,919
JBrowse link
G Pa2g4 proliferation-associated 2G4 decreases expression ISO geraniol results in decreased expression of PA2G4 mRNA CTD PMID:27683099 NCBI chr 7:984,795...992,264
Ensembl chr 7:983,971...992,331
JBrowse link
G Pbx1 PBX homeobox 1 decreases expression ISO geraniol results in decreased expression of PBX1 mRNA CTD PMID:27683099 NCBI chr13:80,278,766...80,588,563
Ensembl chr13:80,278,770...80,588,594
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions
decreases expression
EXP
ISO
geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of PCNA protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of PCNA mRNA]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of PCNA protein]; geraniol inhibits the reaction [Diethylnitrosamine results in increased expression of PCNA protein]; geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA protein]
geraniol results in decreased expression of PCNA protein
CTD PMID:21907755 PMID:26154255 PMID:26364502 PMID:27046949 PMID:28428697 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pgr progesterone receptor multiple interactions EXP geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of PGR protein] CTD PMID:28428697 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Phb1 prohibitin 1 decreases expression
multiple interactions
ISO
EXP
geraniol results in decreased expression of PHB1 mRNA
geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PHB1 protein]
CTD PMID:26695085 PMID:27683099 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
JBrowse link
G Phf1 PHD finger protein 1 increases expression ISO geraniol results in increased expression of PHF1 mRNA CTD PMID:27683099 NCBI chr20:5,017,765...5,022,872
Ensembl chr20:5,017,893...5,022,871
JBrowse link
G Phf21a PHD finger protein 21A increases expression ISO geraniol results in increased expression of PHF21A mRNA CTD PMID:27683099 NCBI chr 3:78,158,760...78,331,903
Ensembl chr 3:78,194,549...78,331,865
JBrowse link
G Phtf1 putative homeodomain transcription factor 1 increases expression ISO geraniol results in increased expression of PHTF1 mRNA CTD PMID:27683099 NCBI chr 2:191,470,849...191,537,399
Ensembl chr 2:191,473,130...191,512,078
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions EXP geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PIK3R1 mRNA] CTD PMID:28428697 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pkmyt1 protein kinase, membrane associated tyrosine/threonine 1 decreases expression ISO geraniol results in decreased expression of PKMYT1 mRNA CTD PMID:27683099 NCBI chr10:12,748,221...12,758,995
Ensembl chr10:12,748,237...12,758,995
JBrowse link
G Plagl1 PLAG1 like zinc finger 1 increases expression ISO geraniol results in increased expression of PLAGL1 mRNA CTD PMID:27683099 NCBI chr 1:7,477,295...7,517,229
Ensembl chr 1:7,477,177...7,517,228
JBrowse link
G Plk1 polo-like kinase 1 decreases expression ISO geraniol results in decreased expression of PLK1 mRNA CTD PMID:27683099 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit decreases expression ISO geraniol results in decreased expression of POLA1 mRNA CTD PMID:27683099 NCBI chr  X:58,034,617...58,348,612
Ensembl chr  X:58,034,619...58,348,536
JBrowse link
G Pole DNA polymerase epsilon, catalytic subunit decreases expression ISO geraniol results in decreased expression of POLE mRNA CTD PMID:27683099 NCBI chr12:46,345,420...46,393,984
Ensembl chr12:46,345,420...46,393,939
JBrowse link
G Polr1g RNA polymerase I subunit G decreases expression ISO geraniol results in decreased expression of POLR1G mRNA CTD PMID:27683099 NCBI chr 1:79,007,490...79,010,766
Ensembl chr 1:79,007,490...79,010,766
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions EXP geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased activity of POR protein] CTD PMID:23499697 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
increases activity
EXP
ISO
geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PPARA mRNA]
geraniol results in increased activity of PPARA protein
CTD PMID:21597168 PMID:26695085 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression
increases activity
multiple interactions
ISO
EXP
geraniol results in decreased expression of PPARG mRNA
geraniol results in increased activity of PPARG protein
geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in decreased expression of PPARG mRNA]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in decreased expression of PPARG protein]
geraniol inhibits the reaction [Fructose results in decreased activity of PPARG protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]
CTD PMID:21597168 PMID:25679220 PMID:26165751 PMID:27683099 PMID:30550845 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Prc1 protein regulator of cytokinesis 1 decreases expression ISO geraniol results in decreased expression of PRC1 mRNA CTD PMID:27683099 NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765
JBrowse link
G Prdm4 PR/SET domain 4 increases expression ISO geraniol results in increased expression of PRDM4 mRNA CTD PMID:27683099 NCBI chr 7:17,953,832...17,980,489
Ensembl chr 7:17,954,019...17,980,489
JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions EXP geraniol inhibits the reaction [Isoproterenol results in decreased expression of PRDX1 mRNA]; geraniol inhibits the reaction [Isoproterenol results in decreased expression of PRDX1 protein] CTD PMID:35608392 NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856
JBrowse link
G Prdx3 peroxiredoxin 3 decreases expression ISO geraniol results in decreased expression of PRDX3 mRNA CTD PMID:27683099 NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions ISO geraniol inhibits the reaction [Rotenone results in increased expression of PRKAA1 protein] CTD PMID:30141137 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions EXP geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of PTEN protein] CTD PMID:28428697 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO
EXP
geraniol inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 mRNA]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; geraniol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of PTGS2 protein]
CTD PMID:20506077 PMID:21597168 PMID:22760862 PMID:23399806 PMID:26190278 More... NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin decreases expression ISO geraniol results in decreased expression of PTTG1 mRNA CTD PMID:27683099 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
JBrowse link
G Pwp1 PWP1 homolog, endonuclein decreases expression ISO geraniol results in decreased expression of PWP1 mRNA CTD PMID:27683099 NCBI chr 7:17,982,730...17,998,728
Ensembl chr 7:17,982,235...17,998,731
JBrowse link
G Racgap1 Rac GTPase-activating protein 1 decreases expression ISO geraniol results in decreased expression of RACGAP1 mRNA CTD PMID:27683099 NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
JBrowse link
G Rad51 RAD51 recombinase decreases expression ISO geraniol results in decreased expression of RAD51 mRNA CTD PMID:27683099 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
JBrowse link
G Rad54b RAD54 homolog B decreases expression ISO geraniol results in decreased expression of RAD54B mRNA CTD PMID:27683099 NCBI chr 5:25,032,112...25,104,630
Ensembl chr 5:25,032,066...25,104,616
JBrowse link
G Rad54l RAD54 like decreases expression ISO geraniol results in decreased expression of RAD54L mRNA CTD PMID:27683099 NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RAF1 protein] CTD PMID:22760862 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rcan1 regulator of calcineurin 1 increases expression ISO geraniol results in increased expression of RCAN1 mRNA CTD PMID:27683099 NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045
JBrowse link
G Rcor3 REST corepressor 3 increases expression ISO geraniol results in increased expression of RCOR3 mRNA CTD PMID:27683099 NCBI chr13:103,624,966...103,665,565
Ensembl chr13:103,624,971...103,665,565
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP
geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of RELA mRNA]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of RELA protein modified form]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of and affects the localization of and results in increased activity of RELA protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of RELA protein modified form]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]
geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of RELA protein]; geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of and affects the localization of RELA protein]; geraniol inhibits the reaction [Doxorubicin results in increased expression of RELA protein]
CTD PMID:23399806 PMID:26190278 PMID:26364502 PMID:28397014 PMID:29050341 More... NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rfx5 regulatory factor X5 increases expression ISO geraniol results in increased expression of RFX5 mRNA CTD PMID:27683099 NCBI chr 2:182,521,191...182,528,720
Ensembl chr 2:182,521,202...182,528,717
JBrowse link
G Rnf19a ring finger protein 19A, RBR E3 ubiquitin protein ligase increases expression ISO geraniol results in increased expression of RNF19A mRNA CTD PMID:27683099 NCBI chr 7:67,425,833...67,465,214
Ensembl chr 7:67,425,837...67,465,222
JBrowse link
G Ruvbl1 RuvB-like AAA ATPase 1 decreases expression ISO geraniol results in decreased expression of RUVBL1 mRNA CTD PMID:27683099 NCBI chr 4:120,932,486...120,967,400
Ensembl chr 4:120,932,417...121,029,384
JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 decreases expression ISO geraniol results in decreased expression of RUVBL2 mRNA CTD PMID:27683099 NCBI chr 1:95,902,014...95,915,247
Ensembl chr 1:95,901,701...95,915,342
JBrowse link
G Satb1 SATB homeobox 1 increases expression ISO geraniol results in increased expression of SATB1 mRNA CTD PMID:27683099 NCBI chr 9:4,677,817...4,773,061
Ensembl chr 9:4,680,920...4,753,251
JBrowse link
G Serpinb3 serpin family B member 3 increases expression ISO geraniol results in increased expression of SERPINB3 mRNA CTD PMID:30806763 NCBI chr13:23,274,120...23,280,660
Ensembl chr13:23,274,484...23,313,682
JBrowse link
G Sim2 SIM bHLH transcription factor 2 increases expression ISO geraniol results in increased expression of SIM2 mRNA CTD PMID:27683099 NCBI chr11:33,414,218...33,453,663
Ensembl chr11:33,414,218...33,453,663
JBrowse link
G Sirt1 sirtuin 1 increases expression ISO geraniol results in increased expression of SIRT1 mRNA CTD PMID:27683099 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Skp2 S-phase kinase associated protein 2 decreases expression ISO geraniol results in decreased expression of SKP2 mRNA CTD PMID:27683099 NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338
JBrowse link
G Slc18a2 solute carrier family 18 member A2 multiple interactions ISO geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SLC18A2 protein] CTD PMID:23943375 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
JBrowse link
G Slc2a4rg SLC2A4 regulator decreases expression ISO geraniol results in decreased expression of SLC2A4RG mRNA CTD PMID:27683099 NCBI chr 3:168,493,975...168,497,616 JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions ISO geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SLC6A3 protein] CTD PMID:23943375 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
G Smad3 SMAD family member 3 decreases expression ISO geraniol results in decreased expression of SMAD3 mRNA CTD PMID:27683099 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Smad6 SMAD family member 6 decreases expression ISO geraniol results in decreased expression of SMAD6 mRNA CTD PMID:27683099 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763
JBrowse link
G Smad7 SMAD family member 7 increases expression ISO geraniol results in increased expression of SMAD7 mRNA CTD PMID:27683099 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link
G Smarca2 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2 decreases expression ISO geraniol results in decreased expression of SMARCA2 mRNA CTD PMID:27683099 NCBI chr 1:224,191,125...224,358,640
Ensembl chr 1:224,191,125...224,358,684
JBrowse link
G Smarcal1 SNF2 related chromatin remodeling annealing helicase 1 increases expression ISO geraniol results in increased expression of SMARCAL1 mRNA CTD PMID:27683099 NCBI chr 9:74,239,718...74,286,156
Ensembl chr 9:74,240,241...74,286,146
JBrowse link
G Smc4 structural maintenance of chromosomes 4 decreases expression ISO geraniol results in decreased expression of SMC4 mRNA CTD PMID:27683099 NCBI chr 2:153,240,243...153,268,722
Ensembl chr 2:153,240,283...153,271,571
JBrowse link
G Snca synuclein alpha multiple interactions ISO geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SNCA mRNA]; geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SNCA protein]
geraniol inhibits the reaction [Rotenone results in increased expression of SNCA protein]; geraniol inhibits the reaction [SNCA protein results in decreased abundance of Dopamine]; geraniol inhibits the reaction [SNCA protein results in decreased abundance of Glutathione]; geraniol inhibits the reaction [SNCA protein results in increased abundance of Thiobarbituric Acid Reactive Substances]
CTD PMID:24103762 PMID:27026137 PMID:30141137 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP
ISO
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of SOD1 mRNA]
geraniol inhibits the reaction [Rotenone results in decreased activity of SOD1 protein]
CTD PMID:22509279 PMID:30141137 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP
ISO
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of SOD2 mRNA]; [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of SOD2 protein]
geraniol inhibits the reaction [Rotenone results in decreased activity of SOD2 protein]
CTD PMID:22509279 PMID:30141137 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sox9 SRY-box transcription factor 9 decreases expression ISO geraniol results in decreased expression of SOX9 mRNA CTD PMID:27683099 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
G Sp100 SP100 nuclear antigen increases expression ISO geraniol results in increased expression of SP100 mRNA CTD PMID:27683099 NCBI chr 9:86,310,990...86,377,036
Ensembl chr 9:86,311,032...86,377,034
JBrowse link
G Sqstm1 sequestosome 1 increases expression
multiple interactions
ISO geraniol results in increased expression of SQSTM1 mRNA
geraniol inhibits the reaction [Rotenone results in decreased expression of SQSTM1 protein]
CTD PMID:27683099 PMID:30141137 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions EXP geraniol promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of SREBF1 mRNA] CTD PMID:26695085 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 increases expression ISO geraniol results in increased expression of SREBF2 mRNA CTD PMID:23668785 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression ISO geraniol results in increased expression of STAT1 mRNA CTD PMID:27683099 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Stat2 signal transducer and activator of transcription 2 increases expression ISO geraniol results in increased expression of STAT2 mRNA CTD PMID:27683099 NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967
JBrowse link
G Stat6 signal transducer and activator of transcription 6 increases expression ISO geraniol results in increased expression of STAT6 mRNA CTD PMID:27683099 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
JBrowse link
G Stmn1 stathmin 1 decreases expression ISO geraniol results in decreased expression of STMN1 mRNA CTD PMID:27683099 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Sub1 SUB1 regulator of transcription decreases expression ISO geraniol results in decreased expression of SUB1 mRNA CTD PMID:27683099 NCBI chr 2:61,005,646...61,020,486
Ensembl chr 2:61,005,666...61,020,436
Ensembl chr 2:61,005,666...61,020,436
JBrowse link
G Supt16h SPT16 homolog, facilitates chromatin remodeling subunit decreases expression ISO geraniol results in decreased expression of SUPT16H mRNA CTD PMID:27683099 NCBI chr15:24,867,697...24,904,818
Ensembl chr15:24,866,489...24,904,846
JBrowse link
G Supt5h SPT5 homolog, DSIF elongation factor subunit increases expression ISO geraniol results in increased expression of SUPT5H mRNA CTD PMID:27683099 NCBI chr 1:83,586,713...83,616,971
Ensembl chr 1:83,586,718...83,616,892
JBrowse link
G Tardbp TAR DNA binding protein decreases expression ISO geraniol results in decreased expression of TARDBP mRNA CTD PMID:27683099 NCBI chr 5:159,050,518...159,062,218
Ensembl chr 5:159,051,799...159,062,055
JBrowse link
G Tceal1 transcription elongation factor A like 1 increases expression ISO geraniol results in increased expression of TCEAL1 mRNA CTD PMID:27683099 NCBI chr  X:100,058,485...100,060,439
Ensembl chr  X:100,058,132...100,060,551
JBrowse link
G Tcf12 transcription factor 12 increases expression ISO geraniol results in increased expression of TCF12 mRNA CTD PMID:27683099 NCBI chr 8:72,490,447...72,799,265
Ensembl chr 8:72,492,567...72,799,201
JBrowse link
G Tcf25 transcription factor 25 increases expression ISO geraniol results in increased expression of TCF25 mRNA CTD PMID:27683099 NCBI chr19:51,415,341...51,449,725
Ensembl chr19:51,415,543...51,449,723
JBrowse link
G Tcf4 transcription factor 4 decreases expression ISO geraniol results in decreased expression of TCF4 mRNA CTD PMID:27683099 NCBI chr18:62,941,739...63,288,126
Ensembl chr18:62,943,782...63,284,425
JBrowse link
G Tcf7l2 transcription factor 7 like 2 decreases expression ISO geraniol results in decreased expression of TCF7L2 mRNA CTD PMID:27683099 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967
JBrowse link
G Terf1 telomeric repeat binding factor 1 decreases expression ISO geraniol results in decreased expression of TERF1 mRNA CTD PMID:27683099 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340
JBrowse link
G Tfap2a transcription factor AP-2 alpha increases expression ISO geraniol results in increased expression of TFAP2A mRNA CTD PMID:27683099 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507
JBrowse link
G Tfcp2 transcription factor CP2 decreases expression ISO geraniol results in decreased expression of TFCP2 mRNA CTD PMID:27683099 NCBI chr 7:131,616,777...131,658,995
Ensembl chr 7:131,616,785...131,658,939
JBrowse link
G Tfdp1 transcription factor Dp-1 decreases expression ISO geraniol results in decreased expression of TFDP1 mRNA CTD PMID:27683099 NCBI chr16:76,162,040...76,200,871
Ensembl chr16:76,162,043...76,200,817
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of TGFB1 mRNA] CTD PMID:28428697 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 increases expression ISO geraniol results in increased expression of TGIF1 mRNA CTD PMID:27683099 NCBI chr 9:110,748,094...110,757,714
Ensembl chr 9:110,720,921...110,757,802
JBrowse link
G Th tyrosine hydroxylase multiple interactions ISO geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein] CTD PMID:23943375 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Timeless timeless circadian regulator decreases expression ISO geraniol results in decreased expression of TIMELESS mRNA CTD PMID:27683099 NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738
JBrowse link
G Tk1 thymidine kinase 1 decreases expression
multiple interactions
ISO geraniol results in decreased expression of TK1 mRNA
Fluorouracil promotes the reaction [geraniol results in decreased expression of TK1 mRNA]
CTD PMID:15374632 NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920
JBrowse link
G Tle1 TLE family member 1, transcriptional corepressor increases expression ISO geraniol results in increased expression of TLE1 mRNA CTD PMID:27683099 NCBI chr 5:85,851,827...85,934,806
Ensembl chr 5:85,851,827...85,934,774
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TLR4 mRNA]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TLR4 protein] CTD PMID:29050341 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO
EXP
geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of TNF protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]
2-chloro-5-nitrobenzanilide inhibits the reaction [geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of TNF protein]]; geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of TNF protein]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]]; geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]]; geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]]
geraniol results in increased expression of TNF mRNA
geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of TNF protein]; geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF protein]; geraniol inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; geraniol inhibits the reaction [Fructose results in increased secretion of TNF protein]; geraniol inhibits the reaction [Isoproterenol results in increased expression of TNF protein]
CTD PMID:21430599 PMID:23399806 PMID:25679220 PMID:26190278 PMID:26695085 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
EXP
ISO
geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 mRNA]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 protein]
geraniol results in increased expression of TP53 mRNA
CTD PMID:21907755 PMID:27683099 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpx2 TPX2, microtubule nucleation factor decreases expression ISO geraniol results in decreased expression of TPX2 mRNA CTD PMID:27683099 NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468
JBrowse link
G Traip TRAF-interacting protein decreases expression ISO geraniol results in decreased expression of TRAIP mRNA CTD PMID:27683099 NCBI chr 8:108,641,860...108,661,640
Ensembl chr 8:108,641,852...108,661,638
JBrowse link
G Trak1 trafficking kinesin protein 1 increases expression ISO geraniol results in increased expression of TRAK1 mRNA CTD PMID:27683099 NCBI chr 8:120,984,445...121,139,357
Ensembl chr 8:120,984,431...121,139,367
JBrowse link
G Trim29 tripartite motif-containing 29 increases expression ISO geraniol results in increased expression of TRIM29 mRNA CTD PMID:27683099 NCBI chr 8:43,682,221...43,706,992
Ensembl chr 8:43,682,221...43,706,992
JBrowse link
G Trps1 transcriptional repressor GATA binding 1 increases expression ISO geraniol results in increased expression of TRPS1 mRNA CTD PMID:27683099 NCBI chr 7:81,916,668...82,142,733
Ensembl chr 7:81,921,601...82,141,905
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions ISO geraniol binds to and results in increased activity of TRPV1 protein CTD PMID:20686244 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 increases expression ISO geraniol results in increased expression of TSC22D3 mRNA CTD PMID:27683099 NCBI chr  X:104,217,898...104,277,886
Ensembl chr  X:104,217,925...104,276,861
JBrowse link
G Ttk Ttk protein kinase decreases expression ISO geraniol results in decreased expression of TTK mRNA CTD PMID:27683099 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651
JBrowse link
G Tulp3 TUB like protein 3 increases expression ISO geraniol results in increased expression of TULP3 mRNA CTD PMID:27683099 NCBI chr 4:161,590,478...161,632,244
Ensembl chr 4:161,590,479...161,632,149
JBrowse link
G Tulp4 TUB like protein 4 increases expression ISO geraniol results in increased expression of TULP4 mRNA CTD PMID:27683099 NCBI chr 1:46,682,416...46,813,167
Ensembl chr 1:46,682,863...46,809,688
JBrowse link
G Tyms thymidylate synthetase multiple interactions
decreases expression
ISO Fluorouracil promotes the reaction [geraniol results in decreased expression of TYMS mRNA] CTD PMID:15374632 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C decreases expression ISO geraniol results in decreased expression of UBE2C mRNA CTD PMID:27683099 NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339
JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N decreases expression ISO geraniol results in decreased expression of UBE2N mRNA CTD PMID:27683099 NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
JBrowse link
G Ubp1 upstream binding protein 1 decreases expression ISO geraniol results in decreased expression of UBP1 mRNA CTD PMID:27683099 NCBI chr 8:113,869,771...113,915,625
Ensembl chr 8:113,869,979...113,915,625
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions EXP geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of UCP2 protein] CTD PMID:26695085 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO geraniol inhibits the reaction [Palmitic Acid results in increased expression of VCAM1 protein]
geraniol inhibits the reaction [Dietary Fats results in increased expression of VCAM1 protein]
CTD PMID:27107694 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of VEGFA protein] CTD PMID:26364502 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vldlr very low density lipoprotein receptor increases expression ISO geraniol results in increased expression of VLDLR mRNA CTD PMID:26141755 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
JBrowse link
G Xbp1 X-box binding protein 1 increases expression ISO geraniol results in increased expression of XBP1 mRNA CTD PMID:27683099 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Zbtb1 zinc finger and BTB domain containing 1 increases expression ISO geraniol results in increased expression of ZBTB1 mRNA CTD PMID:27683099 NCBI chr 6:95,096,838...95,125,811
Ensembl chr 6:95,096,387...95,118,996
JBrowse link
G Zbtb10 zinc finger and BTB domain containing 10 increases expression ISO geraniol results in increased expression of ZBTB10 mRNA CTD PMID:27683099 NCBI chr 2:92,475,254...92,509,892
Ensembl chr 2:92,479,014...92,512,515
JBrowse link
G Zbtb11 zinc finger and BTB domain containing 11 decreases expression ISO geraniol results in decreased expression of ZBTB11 mRNA CTD PMID:27683099 NCBI chr11:44,598,694...44,652,559
Ensembl chr11:44,616,289...44,651,050
JBrowse link
G Zbtb20 zinc finger and BTB domain containing 20 increases expression ISO geraniol results in increased expression of ZBTB20 mRNA CTD PMID:27683099 NCBI chr11:57,052,129...57,791,214
Ensembl chr11:57,072,880...57,510,210
JBrowse link
G Zfp110 zinc finger protein 110 increases expression ISO geraniol results in increased expression of ZNF274 mRNA CTD PMID:27683099 NCBI chr 1:73,445,303...73,461,112
Ensembl chr 1:73,445,336...73,461,086
JBrowse link
G Zfp189 zinc finger protein 189 increases expression ISO geraniol results in increased expression of ZNF189 mRNA CTD PMID:27683099 NCBI chr 5:63,872,596...63,884,348
Ensembl chr 5:63,872,738...63,884,121
JBrowse link
G Zfp207 zinc finger protein 207 decreases expression ISO geraniol results in decreased expression of ZNF207 mRNA CTD PMID:27683099 NCBI chr10:65,385,807...65,398,086
Ensembl chr10:65,385,740...65,397,386
JBrowse link
G Zfp248 zinc finger protein 248 decreases expression ISO geraniol results in decreased expression of ZNF248 mRNA CTD PMID:27683099 NCBI chr 4:151,605,433...151,630,249
Ensembl chr 4:151,606,495...151,629,850
JBrowse link
G Zfp263 zinc finger protein 263 increases expression ISO geraniol results in increased expression of ZNF263 mRNA CTD PMID:27683099 NCBI chr10:11,764,424...11,774,324
Ensembl chr10:11,764,427...11,771,235
JBrowse link
G Zfp281 zinc finger protein 281 increases expression ISO geraniol results in increased expression of ZNF281 mRNA CTD PMID:27683099 NCBI chr13:48,096,103...48,104,265
Ensembl chr13:48,037,286...48,104,888
JBrowse link
G Zfp329 zinc finger protein 329 increases expression ISO geraniol results in increased expression of ZNF329 mRNA CTD PMID:27683099 NCBI chr 1:73,403,067...73,498,349
Ensembl chr 1:73,402,972...73,422,037
JBrowse link
G Zfp334 zinc finger protein 334 increases expression ISO geraniol results in increased expression of ZNF334 mRNA CTD PMID:27683099 NCBI chr 3:154,112,537...154,125,087
Ensembl chr 3:154,113,561...154,125,057
JBrowse link
G Zfp354a zinc finger protein 354A increases expression ISO geraniol results in increased expression of ZNF354A mRNA CTD PMID:27683099 NCBI chr10:35,396,242...35,408,069
Ensembl chr10:35,396,231...35,408,068
JBrowse link
G Zfp394 zinc finger protein 394 increases expression ISO geraniol results in increased expression of ZNF394 mRNA CTD PMID:27683099 NCBI chr12:9,409,047...9,417,228
Ensembl chr12:9,409,078...9,417,246
JBrowse link
G Zfp410 zinc finger protein 410 increases expression ISO geraniol results in increased expression of ZNF410 mRNA CTD PMID:27683099 NCBI chr 6:103,963,265...103,990,252
Ensembl chr 6:103,964,060...103,990,225
JBrowse link
G Zfp455l1 zinc finger protein 455 like 1 increases expression ISO geraniol results in increased expression of KRBOX4 mRNA CTD PMID:27683099 NCBI chr 1:34,866,934...34,944,939
Ensembl chr 1:34,927,303...34,944,121
JBrowse link
G Zfp467 zinc finger protein 467 increases expression ISO geraniol results in increased expression of ZNF467 mRNA CTD PMID:27683099 NCBI chr 4:77,385,752...77,394,709
Ensembl chr 4:77,385,758...77,392,229
JBrowse link
G Zfp606 zinc finger protein 606 increases expression ISO geraniol results in increased expression of ZNF606 mRNA CTD PMID:27683099 NCBI chr 1:72,981,920...73,022,423
Ensembl chr 1:72,981,989...73,008,072
JBrowse link
G Zfp612 zinc finger protein 612 increases expression ISO geraniol results in increased expression of ZNF23 mRNA CTD PMID:27683099 NCBI chr19:38,053,953...38,071,196
Ensembl chr19:38,053,967...38,067,455
JBrowse link
G Zfp68 zinc finger protein 68 increases expression ISO geraniol results in increased expression of ZNF84 mRNA CTD PMID:27683099 NCBI chr12:16,026,058...16,040,995
Ensembl chr12:16,026,079...16,040,995
JBrowse link
G Zfp75d zinc finger protein 75D increases expression ISO geraniol results in increased expression of ZNF75D mRNA CTD PMID:27683099 NCBI chr  X:134,035,116...134,053,765
Ensembl chr  X:134,036,143...134,051,519
JBrowse link
G Zfp768 zinc finger protein 768 increases expression ISO geraniol results in increased expression of ZNF768 mRNA CTD PMID:27683099 NCBI chr 1:181,966,314...181,968,950
Ensembl chr 1:181,966,316...181,969,147
JBrowse link
G Zhx2 zinc fingers and homeoboxes 2 increases expression ISO geraniol results in increased expression of ZHX2 mRNA CTD PMID:27683099 NCBI chr 7:89,226,358...89,374,266
Ensembl chr 7:89,226,463...89,374,378
JBrowse link
G Zmiz1 zinc finger, MIZ-type containing 1 increases expression ISO geraniol results in increased expression of ZMIZ1 mRNA CTD PMID:27683099 NCBI chr16:1,027,083...1,232,616
Ensembl chr16:1,027,325...1,232,597
JBrowse link
G Zmym4 zinc finger MYM-type containing 4 increases expression ISO geraniol results in increased expression of ZMYM4 mRNA CTD PMID:27683099 NCBI chr 5:139,146,782...139,264,387
Ensembl chr 5:139,146,665...139,264,421
JBrowse link
G Zmynd11 zinc finger, MYND-type containing 11 increases expression ISO geraniol results in increased expression of ZMYND11 mRNA CTD PMID:27683099 NCBI chr17:60,542,669...60,631,913
Ensembl chr17:60,543,077...60,631,902
JBrowse link
G Zscan18 zinc finger and SCAN domain containing 18 increases expression ISO geraniol results in increased expression of ZSCAN18 mRNA CTD PMID:27683099 NCBI chr 1:73,332,883...73,349,846
Ensembl chr 1:73,332,889...73,345,897
JBrowse link
G Zzz3 zinc finger, ZZ-type containing 3 increases expression ISO geraniol results in increased expression of ZZZ3 mRNA CTD PMID:27683099 NCBI chr 2:241,330,366...241,397,308
Ensembl chr 2:241,331,022...241,397,307
JBrowse link
geranyl acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO geranyl acetate results in increased expression of BAX protein CTD PMID:29745075 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO geranyl acetate results in decreased expression of BCL2 protein CTD PMID:29745075 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
geranyl diphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases abundance
ISO [geranylgeraniol co-treated with geranyl pyrophosphate] results in decreased expression of HMGCR protein; Lovastatin inhibits the reaction [HMGCR protein results in increased abundance of geranyl diphosphate] CTD PMID:19819230 PMID:19856009 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Mvk mevalonate kinase decreases activity
multiple interactions
ISO geranyl diphosphate results in decreased activity of MVK protein
geranyl diphosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; geranyl diphosphate inhibits the reaction [MVK protein results in increased phosphorylation of Mevalonic Acid]
CTD PMID:9392419 NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family multiple interactions ISO [geranylgeraniol co-treated with geranyl pyrophosphate] results in decreased expression of RAP1A protein modified form CTD PMID:19819230 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
JBrowse link
geranylgeraniol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b10 aldo-keto reductase family 1 member B10 increases chemical synthesis ISO AKR1B10 protein results in increased chemical synthesis of geranylgeraniol CTD PMID:21187079 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases chemical synthesis ISO AKR1C3 protein results in increased chemical synthesis of geranylgeraniol CTD PMID:21187079 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Casp3 caspase 3 increases activity ISO geranylgeraniol results in increased activity of CASP3 protein CTD PMID:9175767 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cav1 caveolin 1 multiple interactions ISO geranylgeraniol inhibits the reaction [rosiglitazone results in increased expression of CAV1 mRNA] CTD PMID:15314095 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions ISO geranylgeraniol inhibits the reaction [Zoledronic Acid results in decreased expression of CCN1 protein] CTD PMID:19530242 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Egf epidermal growth factor multiple interactions ISO geranylgeraniol analog inhibits the reaction [EGF protein results in increased phosphorylation of RHOA protein] CTD PMID:24587105 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO geranylgeraniol inhibits the reaction [Fluvastatin results in decreased expression of F3 protein]; geranylgeraniol inhibits the reaction [Simvastatin results in decreased expression of F3] CTD PMID:9081680 PMID:12753293 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
decreases activity
ISO [geranylgeraniol co-treated with geranyl pyrophosphate] results in decreased expression of HMGCR protein; [MVK gene mutant form results in increased activity of HMGCR protein] which results in increased susceptibility to geranylgeraniol; MVK gene mutant form promotes the reaction [geranylgeraniol results in decreased activity of HMGCR protein] CTD PMID:12477733 PMID:19819230 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Ibsp integrin-binding sialoprotein multiple interactions ISO geranylgeraniol inhibits the reaction [zoledronic acid results in increased expression of IBSP mRNA] CTD PMID:15324309 NCBI chr14:5,439,825...5,452,570
Ensembl chr14:5,439,829...5,452,693
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO geranylgeraniol inhibits the reaction [[MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased expression of IL1B protein]
geranylgeraniol inhibits the reaction [[Alendronate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]
CTD PMID:20304105 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Itga2 integrin subunit alpha 2 multiple interactions ISO
EXP
geranylgeraniol inhibits the reaction [Atorvastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]]; geranylgeraniol inhibits the reaction [Pravastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]] CTD PMID:12500026 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481
JBrowse link
G Itgb1 integrin subunit beta 1 multiple interactions ISO
EXP
geranylgeraniol inhibits the reaction [Atorvastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]]; geranylgeraniol inhibits the reaction [Pravastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]] CTD PMID:12500026 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Mvk mevalonate kinase multiple interactions ISO [MVK gene mutant form results in increased activity of HMGCR protein] which results in increased susceptibility to geranylgeraniol; geranylgeraniol inhibits the reaction [[MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased expression of IL1B protein]; geranylgeraniol inhibits the reaction [MVK gene mutant form results in increased susceptibility to Lipopolysaccharides]; MVK gene mutant form promotes the reaction [geranylgeraniol results in decreased activity of HMGCR protein] CTD PMID:12477733 PMID:20304105 NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882
JBrowse link
G Myl9 myosin light chain 9 multiple interactions ISO geranylgeraniol analog inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MYL9 protein] CTD PMID:24587105 NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333
JBrowse link
G Plat plasminogen activator, tissue type multiple interactions ISO geranylgeraniol inhibits the reaction [Simvastatin results in increased expression of PLAT mRNA]; geranylgeraniol inhibits the reaction [Simvastatin results in increased expression of PLAT] CTD PMID:12371961 PMID:12753293 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO geranylgeraniol inhibits the reaction [cerivastatin promotes the reaction [Bezafibrate results in increased activity of [PPARA protein binds to RXRA protein]]] CTD PMID:11779144 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A multiple interactions EXP geranylgeraniol inhibits the reaction [Simvastatin inhibits the reaction [Phenylephrine results in increased phosphorylation of PPP1R12A protein]] CTD PMID:24449418 NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425
JBrowse link
G Ppp1r14a protein phosphatase 1, regulatory (inhibitor) subunit 14A multiple interactions EXP geranylgeraniol inhibits the reaction [Simvastatin inhibits the reaction [Phenylephrine results in increased phosphorylation of PPP1R14A protein]] CTD PMID:24449418 NCBI chr 1:84,583,127...84,590,743
Ensembl chr 1:84,586,627...84,590,671
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO geranylgeraniol inhibits the reaction [Lovastatin affects the localization of RAC1 protein]
Geranylgeraniol inhibits the reaction [Ropivacaine decreases activity of RAC1 protein in esophageal carcinoma cells]
CTD
RGD
PMID:12933658 PMID:29777701 RGD:155230817 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family multiple interactions ISO [geranylgeraniol co-treated with geranyl pyrophosphate] results in decreased expression of RAP1A protein modified form; geranylgeraniol inhibits the reaction [zoledronic acid results in decreased geranoylation of RAP1A protein] CTD PMID:16539721 PMID:19819230 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
JBrowse link
G Rhoa ras homolog family member A multiple interactions ISO
EXP
geranylgeraniol analog inhibits the reaction [EGF protein results in increased phosphorylation of RHOA protein]; geranylgeraniol analog inhibits the reaction [lysophosphatidic acid results in increased activity of RHOA protein]; geranylgeraniol inhibits the reaction [Lovastatin affects the localization of RHOA protein]; geranylgeraniol inhibits the reaction [Simvastatin results in decreased geranoylation of and affects the localization of RHOA protein]; geranylgeraniol inhibits the reaction [Zoledronic Acid results in decreased expression of and affects the localization of RHOA protein]
geranylgeraniol inhibits the reaction [Lovastatin affects the localization of RHOA protein]; geranylgeraniol inhibits the reaction [Simvastatin inhibits the reaction [Phenylephrine results in increased activity of RHOA protein]]
CTD PMID:9398081 PMID:12477733 PMID:12933658 PMID:15324309 PMID:24449418 More... NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rhoc ras homolog family member C multiple interactions ISO geranylgeraniol analog inhibits the reaction [lysophosphatidic acid results in increased activity of RHOC protein] CTD PMID:24587105 NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO geranylgeraniol inhibits the reaction [cerivastatin promotes the reaction [Bezafibrate results in increased activity of [PPARA protein binds to RXRA protein]]] CTD PMID:11779144 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Sele selectin E multiple interactions ISO geranylgeraniol inhibits the reaction [Simvastatin promotes the reaction [TNF protein results in increased expression of SELE protein]] CTD PMID:16740276 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO geranylgeraniol inhibits the reaction [Simvastatin promotes the reaction [TNF protein results in increased expression of SELE protein]] CTD PMID:16740276 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
solanesol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO 2-phenylacetylenesulfonamide inhibits the reaction [solanesol inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]]; solanesol inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]; solanesol promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]]; tin protoporphyrin IX inhibits the reaction [solanesol inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]] CTD PMID:25645596 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase multiple interactions ISO solanesol inhibits the reaction [Glucose results in decreased activity of CAT protein] CTD PMID:37586544 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cul3 cullin 3 multiple interactions ISO solanesol inhibits the reaction [KEAP1 protein binds to CUL3 protein binds to RBX1 protein] CTD PMID:25645596 NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO solanesol inhibits the reaction [Glucose results in increased secretion of GPT protein] CTD PMID:37586544 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO geldanamycin inhibits the reaction [solanesol results in increased expression of HMOX1 mRNA]; geldanamycin inhibits the reaction [solanesol results in increased expression of HMOX1 protein]; solanesol inhibits the reaction [Glucose results in decreased expression of HMOX1 mRNA]; solanesol inhibits the reaction [Glucose results in decreased expression of HMOX1 protein]
solanesol results in increased expression of HMOX1 mRNA; solanesol results in increased expression of HMOX1 protein
CTD PMID:25645596 PMID:37586544 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hsf1 heat shock transcription factor 1 multiple interactions
affects localization
ISO 2-phenylacetylenesulfonamide inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; geldanamycin inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; N2-(1H-indazole-5-yl)-N6-methyl-3-nitropyridine-2,6-diamine inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]
solanesol affects the localization of HSF1 protein
CTD PMID:25645596 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions ISO solanesol inhibits the reaction [Glucose results in increased expression of KEAP1 mRNA]; solanesol inhibits the reaction [Glucose results in increased expression of KEAP1 protein]; solanesol inhibits the reaction [KEAP1 protein binds to CUL3 protein binds to RBX1 protein]; solanesol inhibits the reaction [KEAP1 protein binds to NFE2L2 protein] CTD PMID:25645596 PMID:37586544 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO solanesol affects the localization of and results in increased activity of NFE2L2 protein; solanesol inhibits the reaction [Glucose results in decreased expression of NFE2L2 mRNA]; solanesol inhibits the reaction [Glucose results in decreased expression of NFE2L2 protein]; solanesol inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]; solanesol results in decreased ubiquitination of and results in decreased degradation of NFE2L2 protein CTD PMID:25645596 PMID:37586544 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO solanesol inhibits the reaction [Glucose results in decreased expression of NQO1 mRNA]; solanesol inhibits the reaction [Glucose results in decreased expression of NQO1 protein] CTD PMID:37586544 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Rbx1 ring-box 1 multiple interactions ISO solanesol inhibits the reaction [KEAP1 protein binds to CUL3 protein binds to RBX1 protein] CTD PMID:25645596 NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051
JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 multiple interactions ISO 2-phenylacetylenesulfonamide inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; geldanamycin inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; N2-(1H-indazole-5-yl)-N6-methyl-3-nitropyridine-2,6-diamine inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]]; solanesol promotes the reaction [HSF1 protein binds to STUB1 protein] CTD PMID:25645596 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19898
    chemical entity 19896
      atom 19896
        nonmetal atom 19818
          carbon atom 19771
            organic molecular entity 19771
              isoprenoid 14074
                prenols 528
                  polyprenol 519
                    (2E,6E,10E)-omega-hydroxyfarnesol 0
                    (2E,6E,10Z,14Z,18Z,22E)-3,7,11,15,19,23,27,31,35-Nonamethylhexatriaconta-2,6,10,14,18,22-hexaen-1-ol 0
                    3,7-dimethylocta-2,6-dien-1-ol + 399
                    Bionectin F 0
                    Dolichol-16 0
                    Dolichol-17 0
                    Dolichol-18 0
                    Dolichol-19 0
                    Glisoprenin A 0
                    Glisoprenin B 0
                    Glisoprenin D 0
                    Glisoprenin E 0
                    Glisoprenin F 0
                    Gymnoprenol A10 0
                    Gymnoprenol A9 0
                    SCH 60057 0
                    SCH 60061 0
                    SCH 66878 0
                    archaeal dolichol + 0
                    decaprenol 0
                    ditrans,polycis-polyprenol + 0
                    dolichol + 1
                    farnesol + 112
                    geranylgeraniol + 25
                    hexaprenols + 0
                    nonaprenol + 11
                    octaprenols + 0
                    omega-hydroxygeranylgeraniol 0
                    polyprenol phosphate + 66
                    undecaprenols + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19898
    subatomic particle 19896
      composite particle 19896
        hadron 19896
          baryon 19896
            nucleon 19896
              atomic nucleus 19896
                atom 19896
                  main group element atom 19835
                    p-block element atom 19835
                      chalcogen 19586
                        oxygen atom 19558
                          oxygen molecular entity 19558
                            hydroxides 19365
                              organic hydroxy compound 18978
                                alcohol 15732
                                  prenols 528
                                    polyprenol 519
                                      (2E,6E,10E)-omega-hydroxyfarnesol 0
                                      (2E,6E,10Z,14Z,18Z,22E)-3,7,11,15,19,23,27,31,35-Nonamethylhexatriaconta-2,6,10,14,18,22-hexaen-1-ol 0
                                      3,7-dimethylocta-2,6-dien-1-ol + 399
                                      Bionectin F 0
                                      Dolichol-16 0
                                      Dolichol-17 0
                                      Dolichol-18 0
                                      Dolichol-19 0
                                      Glisoprenin A 0
                                      Glisoprenin B 0
                                      Glisoprenin D 0
                                      Glisoprenin E 0
                                      Glisoprenin F 0
                                      Gymnoprenol A10 0
                                      Gymnoprenol A9 0
                                      SCH 60057 0
                                      SCH 60061 0
                                      SCH 66878 0
                                      archaeal dolichol + 0
                                      decaprenol 0
                                      ditrans,polycis-polyprenol + 0
                                      dolichol + 1
                                      farnesol + 112
                                      geranylgeraniol + 25
                                      hexaprenols + 0
                                      nonaprenol + 11
                                      octaprenols + 0
                                      omega-hydroxygeranylgeraniol 0
                                      polyprenol phosphate + 66
                                      undecaprenols + 0
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