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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dolichol
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Accession:CHEBI:16091 term browser browse the term
Definition:Any one of a group of prenol derivatives made up of varying numbers of cis-linked isoprene units, terminating in an alpha-saturated isoprenoid group containing an alcohol functional group, with the three isoprene units at the distal end trans-linked.
Synonyms:exact_synonym: alpha-(4-hydroxy-2-methylbutyl)-omega-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]poly[(2Z)-2-methylbut-2-ene-1,4-diyl]
 related_synonym: 2,3-dihydropolyprenol;   Formula=(C5H8)nC20H36O;   di-trans,poly-cis-dolichol;   dolichols
 alt_id: CHEBI:14190;   CHEBI:23877;   CHEBI:4686;   CHEBI:57636;   CHEBI:67131
 xref: KEGG:C00381;   PMID:12702274;   PMID:14739709;   PMID:20637498;   PMID:21570481;   PMID:22717794;   PMID:23059969;   PMID:8486680


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dolichyl phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mvk mevalonate kinase decreases activity
multiple interactions		 ISO dolichol monophosphate results in decreased activity of MVK protein
dolichol monophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; dolichol monophosphate inhibits the reaction [MVK protein results in increased phosphorylation of Mevalonic Acid]		 CTD PMID:9392419 NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    chemical entity 19878
      atom 19878
        nonmetal atom 19800
          carbon atom 19754
            organic molecular entity 19754
              isoprenoid 14066
                dolichol 1
                  acyldolichol + 1
                  dolichyl group 0
                  dolichyl phosphate + 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      chalcogen 19569
                        oxygen atom 19541
                          oxygen molecular entity 19541
                            hydroxides 19347
                              organic hydroxy compound 18957
                                alcohol 15719
                                  prenols 528
                                    polyprenol 519
                                      dolichol 1
                                        acyldolichol + 1
                                        dolichyl group 0
                                        dolichyl phosphate + 1
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