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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dolichol
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Accession:CHEBI:16091 term browser browse the term
Definition:Any one of a group of prenol derivatives made up of varying numbers of cis-linked isoprene units, terminating in an alpha-saturated isoprenoid group containing an alcohol functional group, with the three isoprene units at the distal end trans-linked.
Synonyms:exact_synonym: alpha-(4-hydroxy-2-methylbutyl)-omega-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]poly[(2Z)-2-methylbut-2-ene-1,4-diyl]
 related_synonym: 2,3-dihydropolyprenol;   Formula=(C5H8)nC20H36O;   dolichols
 alt_id: CHEBI:14190;   CHEBI:23877;   CHEBI:4686;   CHEBI:57636;   CHEBI:67131
 xref: KEGG:C00381;   PMID:12702274;   PMID:14739709;   PMID:20637498;   PMID:21570481;   PMID:22717794;   PMID:23059969;   PMID:8486680


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dolichyl phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mvk mevalonate kinase decreases activity
multiple interactions
ISO dolichol monophosphate results in decreased activity of MVK protein
dolichol monophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; dolichol monophosphate inhibits the reaction [MVK protein results in increased phosphorylation of Mevalonic Acid]
CTD PMID:9392419 NCBI chr12:47,904,266...47,920,457
Ensembl chr12:47,904,719...47,919,400
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    chemical entity 19816
      atom 19814
        nonmetal atom 19690
          carbon atom 19597
            organic molecular entity 19597
              isoprenoid 9607
                dolichol 1
                  acyldolichol + 1
                  dolichyl group 0
                  dolichyl phosphate + 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      chalcogen 19399
                        oxygen atom 19361
                          oxygen molecular entity 19361
                            hydroxides 19107
                              organic hydroxy compound 18661
                                alcohol 15008
                                  prenols 514
                                    polyprenol 505
                                      dolichol 1
                                        acyldolichol + 1
                                        dolichyl group 0
                                        dolichyl phosphate + 1
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