bladder disease - Ontology Report - Rat Genome Database

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RGD DISEASE ONTOLOGY - ANNOTATIONS

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RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:	bladder disease	go back to main search page
Accession:	DOID:365	browse the term
Definition:	A urinary system disease that is located_in the bladder. (DO)
Synonyms:	exact_synonym:	bladder diseases; urinary bladder disease; urinary bladder diseases
	primary_id:	MESH:D001745
	xref:	EFO:1000018; ICD10CM:N32.9; ICD9CM:596.9; NCI:C2900
For additional species annotation, visit the Alliance of Genome Resources.

show annotations for term's descendants Sort by:
Rat (448) Mouse (453) Human (2514) Chinchilla (392) Bonobo (427) Dog (432) Squirrel (401) Pig (433) Green Monkey (418) Naked Mole-rat (395) All
Genes (448)

bladder disease

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cholinergic receptor, muscarinic 3

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:22077972 PMID:17922784

NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278

G

fibroblast growth factor 2

associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:urinary bladder

RGD

NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221

G

insulin 2

CTD Direct Evidence: therapeutic

NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775

G

nerve growth factor

associated with Diabetes Mellitus, Experimental

RGD

NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452

G

Ras association domain family member 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:108,225,023...108,236,164
Ensembl chr 8:108,225,023...108,236,164

G

regulator of G-protein signaling 2

treatment

associated with hypertension

RGD

NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385

G

regulator of G-protein signaling 3

treatment

associated with hypertension

RGD

NCBI chr 5:76,022,038...76,161,895
Ensembl chr 5:76,022,001...76,161,894

G

regulator of G-protein signaling 4

treatment

associated with hypertension

RGD

NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068

G

solute carrier family 18 member A3

associated with Spinal Cord Injuries;protein:decreased expression:axon terminus

RGD

NCBI chr16:7,713,630...7,716,491

G

TIMP metallopeptidase inhibitor 3

CTD Direct Evidence: marker/mechanism

NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839

G

vasoactive intestinal peptide

CTD Direct Evidence: marker/mechanism

NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216

acute cystitis

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

lipocalin 2

disease_progression

associated with urinary tract infection;

RGD

NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095

bladder calculus

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aryl hydrocarbon receptor

CTD Direct Evidence: marker/mechanism

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

bladder carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

fibroblast growth factor receptor 3

ClinVar Annotator: match by term: Urinary bladder carcinoma

PMID:7773297 PMID:8589699 PMID:8845844 PMID:9438390 PMID:9790257 More...

NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341

G

HRas proto-oncogene, GTPase

ClinVar Annotator: match by term: Urinary bladder carcinoma

PMID:16170316 PMID:16372351 PMID:16443854 PMID:16835863 PMID:17601930 More...

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

G

leucine rich repeat containing 56

ClinVar Annotator: match by term: Urinary bladder carcinoma

PMID:16170316 PMID:16372351 PMID:16443854 PMID:16835863 PMID:17601930 More...

NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172

G

polyamine-modulated factor 1

disease_progression

RGD

NCBI chr 2:173,848,074...173,868,272
Ensembl chr 2:173,848,074...173,868,270

bladder diverticulum

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

EGF containing fibulin extracellular matrix protein 1

ClinVar Annotator: match by term: Diverticulum of bladder

PMID:25741868 PMID:31792352

NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018

BLADDER DYSFUNCTION, AUTONOMIC, WITH IMPAIRED PUPILLARY REFLEX AND SECONDARY CAKUT

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cholinergic receptor nicotinic alpha 3 subunit

ClinVar Annotator: match by term: CHRNA3-related condition | ClinVar Annotator: match by term: Urinary bladder, atony of

PMID:25741868 PMID:28492532 PMID:31708116

NCBI chr 8:55,401,668...55,415,165
Ensembl chr 8:55,401,702...55,415,165

bladder exstrophy

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

leucine zipper like post translational regulator 1

ClinVar Annotator: match by term: Bladder exstrophy

PMID:25741868 PMID:28492532 PMID:31044557

NCBI chr11:83,487,717...83,503,896
Ensembl chr11:83,487,717...83,503,633

G

tumor protein p63

OMIM:600057

NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398

bladder neck obstruction

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adrenoceptor alpha 1A

RGD

NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500

G

collagen type I alpha 1 chain

treatment

RGD

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

collagen type III alpha 1 chain

treatment

RGD

NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547

G

cytochrome P450, family 19, subfamily a, polypeptide 1

RGD

NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758

G

elastin

treatment

RGD

NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928

G

hypoxia inducible factor 1 subunit alpha

protein:increased expression:urinary bladder (rat)

RGD

NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261

G

5-hydroxytryptamine receptor 2A

mRNA:increased expression:urinary bladder

RGD

NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928

G

matrix metallopeptidase 7

treatment

RGD

NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902

G

nerve growth factor

treatment

RGD

NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452

G

nitric oxide synthase 3

mRNA:decreased expression:urinary bladder

RGD

NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166

G

optineurin

protein:increased expression:urinary bladder:

RGD

NCBI chr17:73,209,572...73,260,251
Ensembl chr17:73,209,575...73,260,251

G

prostaglandin-endoperoxide synthase 2

CTD Direct Evidence: marker/mechanism

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

superoxide dismutase 2

RGD

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

bladder squamous cell carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

phosphatase and tensin homolog

disease_progression

associated with schistosomiasis;protein:decreased expression:urothelium (human)

RGD

NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838

bladder urothelial carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

actin-like 7a

RGD

NCBI chr 5:71,447,447...71,450,440
Ensembl chr 5:71,447,071...71,450,908

G

baculoviral IAP repeat-containing 5

disease_progression

mRNA:increased expression:urinary bladder (human)

NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380

G

baculoviral IAP repeat-containing 7

disease_progression

mRNA:increased expression:urinary bladder (human)

NCBI chr 3:168,047,824...168,052,606
Ensembl chr 3:168,047,824...168,052,606

G

fibroblast growth factor receptor 3

severity

protein:increased expression:urothelial cells (human)

RGD

NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341

G

lysine demethylase 6A

susceptibility

associated with upper tract urothelial carcinoma; DNA:mutations:multiple: (human)

RGD

NCBI chr X:4,337,466...4,477,100
Ensembl chr X:4,337,750...4,477,062

CAKUT

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

angiotensin I converting enzyme

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131

G

actin, gamma 1

ClinVar Annotator: match by term: Congenital anomalies of the kidney and urinary tract

PMID:3351890 PMID:13680526 PMID:18414213 PMID:22366783 PMID:25052316 More...

NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232

G

BicC family RNA binding protein 1

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

NCBI chr20:17,449,639...17,686,775
Ensembl chr20:17,449,560...17,686,776

G

bone morphogenetic protein 4

susceptibility

DNA:SNPs: :rs2071047,rs17563(human)

RGD

NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306

G

bone morphogenetic protein 7

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788

G

cell division cycle 5-like

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

NCBI chr 9:15,564,949...15,603,453
Ensembl chr 9:15,564,767...15,603,450

G

chromodomain helicase DNA binding protein 1-like

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

NCBI chr 2:185,138,526...185,217,498
Ensembl chr 2:185,139,308...185,217,595

G

collagen type IV alpha 1 chain

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract | ClinVar Annotator: match by term: Congenital anomalies of the kidney and urinary tract

PMID:25741868 PMID:28492532 PMID:31230195

NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412

G

cytosolic thiouridylase subunit 2

ClinVar Annotator: match by term: Congenital anomalies of the kidney and urinary tract

PMID:28492532 PMID:30143558 PMID:33057194 PMID:35982159

NCBI chr19:50,539,184...50,544,629
Ensembl chr19:50,539,352...50,544,623

G

DEAH-box helicase 8

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

NCBI chr10:86,667,641...86,704,198
Ensembl chr10:86,667,834...86,705,137

G

deoxyribonuclease 1

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

PMID:25741868 PMID:28492532 PMID:30143558

NCBI chr10:11,498,930...11,505,151
Ensembl chr10:11,498,931...11,501,869

G

ER membrane protein complex subunit 1

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

PMID:26572623 PMID:26942288 PMID:27657687 PMID:28492532 PMID:29271071

NCBI chr 5:151,608,557...151,633,888
Ensembl chr 5:151,608,568...151,633,888

G

ETS variant transcription factor 4

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974

G

FAT atypical cadherin 4

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

PMID:25741868 PMID:28492532 PMID:28878612 PMID:30143558

NCBI chr 2:121,927,266...122,056,700
Ensembl chr 2:121,927,942...122,056,707

G

forkhead box C1

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract | ClinVar Annotator: match by term: Congenital anomalies of the kidney and urinary tract

PMID:25741868 PMID:28492532 PMID:30143558 PMID:32475988

NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803

G

Fraser extracellular matrix complex subunit 1

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract | ClinVar Annotator: match by term: Congenital anomalies of the kidney and urinary tract

PMID:12766769 PMID:16199547 PMID:18671281 PMID:25741868 PMID:28492532 More...

NCBI chr14:12,791,407...13,200,862
Ensembl chr14:12,793,599...13,200,726

G

Fras1 related extracellular matrix 1

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

PMID:25741868 PMID:28492532

NCBI chr 5:97,321,266...97,469,523
Ensembl chr 5:97,322,538...97,469,543

G

FRAS1 related extracellular matrix 2

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract | ClinVar Annotator: match by term: Congenital anomalies of the kidney and urinary tract

PMID:24700879 PMID:25741868 PMID:28492532 PMID:30143558

NCBI chr 2:137,602,784...137,740,785
Ensembl chr 2:137,602,784...137,740,785

G

GATA binding protein 3

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391

G

growth differentiation factor 6

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract | ClinVar Annotator: match by term: Congenital anomalies of the kidney and urinary tract

PMID:18425797 PMID:19129173 PMID:23307924 PMID:24033266 PMID:25741868 More...

NCBI chr 5:22,996,246...23,012,567
Ensembl chr 5:22,996,246...23,012,567

G

GREB1 like retinoic acid receptor coactivator

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

PMID:25741868 PMID:29100090 PMID:30143558

NCBI chr18:1,392,330...1,629,483
Ensembl chr18:1,392,725...1,628,067

G

HNF1 homeobox B

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

PMID:15930087 PMID:16249435 PMID:16371430 PMID:17116179 PMID:18249217 More...

NCBI chr10:68,735,894...68,789,888
Ensembl chr10:68,735,894...68,789,888

G

heparanase 2 (inactive)

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract | ClinVar Annotator: match by term: Congenital anomalies of the kidney and urinary tract

PMID:19669792 PMID:20560210 PMID:25510506 PMID:27151922 PMID:28492532 More...

NCBI chr 1:241,582,904...242,284,348
Ensembl chr 1:241,583,187...242,246,118

G

heat shock protein family A (Hsp70) member 1B

DNA: SNP: :g.1267A>G

RGD

NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240

G

jagged canonical Notch ligand 1

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

PMID:25741868 PMID:28492532

NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209

G

lysine acetyltransferase 6B

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

PMID:28492532 PMID:30143558

NCBI chr15:2,638,885...2,811,977
Ensembl chr15:2,639,200...2,812,316

G

lysine methyltransferase 2D

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

NCBI chr 7:129,980,744...130,022,088
Ensembl chr 7:129,962,887...130,020,325

G

LIF receptor subunit alpha

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

MouseDO
ClinVar

PMID:25741868 PMID:26627873 PMID:28334964 PMID:28492532 PMID:34063511 More...

NCBI chr 2:56,224,393...56,292,988
Ensembl chr 2:56,250,120...56,286,699

G

notch receptor 2

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

PMID:25741868 PMID:28492532 PMID:30143558

NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088

G

nephrocystin 1

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

NCBI chr 3:114,960,650...115,016,234
Ensembl chr 3:114,960,650...115,016,234

G

nephrocystin 4

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

PMID:28492532 PMID:30143558

NCBI chr 5:162,986,157...163,073,708
Ensembl chr 5:162,988,370...163,073,706

G

nuclear receptor interacting protein 1

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

PMID:28381549 PMID:30143558

NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761

G

Ofd1 centriole and centriolar satellite protein

ClinVar Annotator: match by term: Congenital anomalies of the kidney and urinary tract

PMID:25741868 PMID:28492532

NCBI chr X:28,015,347...28,056,115
Ensembl chr X:28,015,347...28,056,110

G

paired box 2

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

PMID:3377002 PMID:8589702 PMID:9106533 PMID:11093271 PMID:11241473 More...

NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321

G

RNA polymerase I and III subunit C

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

NCBI chr 9:14,735,740...14,739,852
Ensembl chr 9:14,735,714...14,739,852

G

ret proto-oncogene

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract | ClinVar Annotator: match by term: Congenital anomalies of the kidney and urinary tract

PMID:25741868 PMID:27657687 PMID:28492532 PMID:29641532

NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176

G

roundabout guidance receptor 1

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract | ClinVar Annotator: match by term: Congenital anomalies of the kidney and urinary tract

PMID:25741868 PMID:28492532 PMID:30692597 PMID:35227688

NCBI chr11:10,580,863...11,621,675
Ensembl chr11:10,580,908...11,620,203

G

roundabout guidance receptor 2

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract | ClinVar Annotator: match by term: Congenital anomalies of the kidney and urinary tract

PMID:17357069 PMID:18235093 PMID:22995991 PMID:23536131 PMID:24429398 More...

NCBI chr11:12,528,949...14,096,726
Ensembl chr11:12,528,951...13,041,536

G

spalt-like transcription factor 1

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

PMID:25741868 PMID:28492532 PMID:30143558

NCBI chr19:18,005,782...18,022,705
Ensembl chr19:18,007,503...18,022,705

G

SIX homeobox 2

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

PMID:25741868 PMID:27657687 PMID:28492532 PMID:32164334

NCBI chr 6:8,974,859...8,981,345
Ensembl chr 6:8,967,157...8,981,193

G

slit guidance ligand 2

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract | ClinVar Annotator: match by term: Congenital anomalies of the kidney and urinary tract

PMID:25741868 PMID:26026792 PMID:28492532

NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948

G

SLIT-ROBO Rho GTPase activating protein 1

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract | ClinVar Annotator: match by term: Congenital anomalies of the kidney and urinary tract

PMID:25741868 PMID:26026792 PMID:30143558

NCBI chr 7:57,329,532...57,594,681
Ensembl chr 7:57,329,532...57,596,196

G

TBC1 domain family member 1

ClinVar Annotator: match by term: Non-syndromic renal or urinary tract malformation

NCBI chr14:43,936,820...44,135,133
Ensembl chr14:43,935,636...44,136,499

G

T-box transcription factor 18

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

PMID:26235987 PMID:30143558

NCBI chr 8:88,652,054...88,680,081
Ensembl chr 8:88,652,054...88,680,058

G

T-box transcription factor 6

CTD Direct Evidence: marker/mechanism

NCBI chr 1:181,387,851...181,392,762
Ensembl chr 1:181,388,684...181,392,593

G

transmembrane protein 231

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

PMID:25741868 PMID:30143558

NCBI chr19:39,883,077...39,904,296
Ensembl chr19:39,883,077...39,904,269

G

TNF receptor-associated protein 1

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

PMID:25741868 PMID:28492532 PMID:30143558

NCBI chr10:11,464,882...11,498,931
Ensembl chr10:11,464,821...11,498,981

G

transcriptional repressor GATA binding 1

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract

PMID:11112658 PMID:11950061 PMID:18946009 PMID:24502542 PMID:25792522 More...

NCBI chr 7:81,916,668...82,142,733
Ensembl chr 7:81,921,601...82,141,905

G

zinc finger MYM-type containing 2

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract | ClinVar Annotator: match by term: Congenital anomalies of the kidney and urinary tract

PMID:25741868 PMID:32891193

NCBI chr15:31,035,835...31,108,945
Ensembl chr15:31,035,838...31,109,357

G

Zn regulated GTPase metalloprotein activator 1A

NCBI chr 1:222,568,278...222,612,937
Ensembl chr 1:222,564,545...222,610,629

CAKUT1

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cadherin, EGF LAG seven-pass G-type receptor 3

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract 1

NCBI chr 8:109,530,597...109,558,360
Ensembl chr 8:109,530,641...109,558,354

G

deoxyribonuclease 1

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract 1

PMID:24152966 PMID:28710113 PMID:35765067

NCBI chr10:11,498,930...11,505,151
Ensembl chr10:11,498,931...11,501,869

G

dual serine/threonine and tyrosine protein kinase

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract 1 | ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract 1, susceptibility to

OMIM
CTD
ClinVar

PMID:9536098 PMID:17273976 PMID:17576681 PMID:23862974 PMID:25741868 More...

NCBI chr13:43,857,266...43,905,280
Ensembl chr13:43,857,266...43,905,269

G

SLIT-ROBO Rho GTPase activating protein 1

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract 1, susceptibility to

PMID:25741868 PMID:26026792 PMID:30143558

NCBI chr 7:57,329,532...57,594,681
Ensembl chr 7:57,329,532...57,596,196

G

TNF receptor-associated protein 1

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract 1

PMID:24152966 PMID:28710113 PMID:35765067

NCBI chr10:11,464,882...11,498,931
Ensembl chr10:11,464,821...11,498,981

G

uroplakin 3A

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract 1 | ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract 1, susceptibility to

PMID:15888565 PMID:16731295 PMID:25741868

NCBI chr 7:116,128,981...116,139,950
Ensembl chr 7:116,134,874...116,139,948

CAKUT2

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

bone morphogenetic protein 4

DNA:mutations:cds: c.485G> A (p.R162Q), c.1167T> C(human)

RGD

NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306

G

matrix metallopeptidase 9

treatment

RGD

NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120

G

T-box transcription factor 18

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract 2 | ClinVar Annotator: match by term: Pelvi-ureteric junction obstruction

OMIM
CTD
ClinVar

PMID:25741868 PMID:25741890 PMID:26235987 PMID:28492532 PMID:30143558

NCBI chr 8:88,652,054...88,680,081
Ensembl chr 8:88,652,054...88,680,058

G

TIMP metallopeptidase inhibitor 1

treatment

RGD

NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664

CAKUT3

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

nuclear receptor interacting protein 1

ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tract 3 | ClinVar Annotator: match by term: NRIP1-related condition

PMID:25741868 PMID:28381549 PMID:28492532 PMID:30143558

NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761

congenital megabladder

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

myocardin

OMIM:618719
ClinVar Annotator: match by term: Megabladder, congenital

OMIM
MouseDO
ClinVar

PMID:25741868 PMID:31513549

NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627

cystinuria

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

centromere protein F

ClinVar Annotator: match by term: Cystinuria

NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669

G

centrosomal protein 89

ClinVar Annotator: match by term: Cystinuria

NCBI chr 1:88,058,211...88,100,114
Ensembl chr 1:88,058,227...88,100,112

G

prolyl endopeptidase-like

ClinVar Annotator: match by term: Cystinuria | ClinVar Annotator: match by term: Cystinuria, non-type I

PMID:7573036 PMID:8054986 PMID:8792820 PMID:9648062 PMID:9768685 More...

NCBI chr 6:9,580,367...9,609,957
Ensembl chr 6:9,580,217...9,607,772

G

solute carrier family 3 member 1

susceptibility

DNA:missense mutations
ClinVar Annotator: match by term: Cystine urolithiasis | ClinVar Annotator: match by term: Cystinuria | ClinVar Annotator: match by term: Cystinuria, non-type I
OMIM:220100
CTD Direct Evidence: marker/mechanism

ClinVar
MouseDO
CTD
OMIM
RGD

PMID:7539209 PMID:7573036 PMID:8054986 PMID:8731106 PMID:8792820 More...

NCBI chr 6:9,608,169...9,641,881
Ensembl chr 6:9,608,178...9,641,907

G

solute carrier family 7 member 9

DNA:missense mutations, nonsense mutations:cds:multiple (human)
ClinVar Annotator: match by term: Cystine urolithiasis | ClinVar Annotator: match by term: Cystinuria | ClinVar Annotator: match by term: SLC7A9-related condition
OMIM:220100
CTD Direct Evidence: marker/mechanism

ClinVar
MouseDO
CTD
OMIM
RGD

PMID:6031738 PMID:9536098 PMID:10471498 PMID:11013083 PMID:11157794 More...

NCBI chr 1:88,109,517...88,132,653
Ensembl chr 1:88,110,644...88,132,641

cystitis

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adenylate cyclase activating polypeptide 1

mRNA:increased expression:urinary bladder urothelium

RGD

NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773

G

ADCYAP receptor type I

mRNA:increased expression:urothelium, detrusor muscle (rat)

RGD

NCBI chr 4:84,593,558...84,642,700
Ensembl chr 4:84,593,892...84,642,700

G

brain-derived neurotrophic factor

RGD

PMID:20079809 PMID:9631447

RGD:5684910, RGD:8657090

NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615

G

catalase

mRNA:decreased expression:urinary bladder

RGD

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

colony stimulating factor 3

protein:increased expression:urinary bladder

RGD

NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603

G

C-X3-C motif chemokine ligand 1

protein:increased expression:urinary bladder urothelium

RGD

NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833

G

C-X3-C motif chemokine receptor 1

protein:increased expression:urinary bladder urothelium

RGD

NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014

G

estrogen receptor 2

protein:decreased expression:bladder

RGD

NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919

G

interleukin 11

CTD Direct Evidence: therapeutic

NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129

G

interleukin 18

protein:increased expression:urine, bladder

RGD

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

G

interleukin 1 beta

mRNA, protein:increased expression:urinary bladder

RGD

PMID:11948286 PMID:23000860

RGD:6907118, RGD:7175333

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 2

RGD

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 4

protein:increased expression:urine

RGD

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

G

kinase insert domain receptor

RGD

NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018

G

lymphotoxin alpha

mRNA:increased expression:urinary bladder

RGD

NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859

G

macrophage migration inhibitory factor

mRNA, protein:increased expression:nervous system

RGD

PMID:12853844 PMID:19066630

RGD:1642002, RGD:4890977

NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504

G

myeloperoxidase

protein:increased activity:bladder

RGD

NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819

G

mucin 2, oligomeric mucus/gel-forming

RGD

NCBI chr 1:196,799,494...196,831,740
Ensembl chr 1:196,799,517...196,831,756

G

mucin 5AC, oligomeric mucus/gel-forming

RGD

NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475

G

nerve growth factor

treatment

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:16889433 PMID:20127836 PMID:11350415 PMID:19996110

RGD:7242782, RGD:7242808, RGD:7242802

NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452

G

nerve growth factor receptor

protein, mRNA:increased expression:lumbosacral dorsal root ganglia

RGD

NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518

G

programmed cell death 1

RGD

NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937

G

proopiomelanocortin

CTD Direct Evidence: marker/mechanism

NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664

G

prostaglandin E receptor 4

RGD

NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670

G

prostaglandin-endoperoxide synthase 2

RGD

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

RELA proto-oncogene, NF-kB subunit

CTD Direct Evidence: marker/mechanism

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

superoxide dismutase 1

mRNA:decreased expression:urinary bladder

RGD

NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249

G

superoxide dismutase 2

mRNA:decreased expression:urinary bladder

RGD

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

G

tachykinin receptor 1

RGD

NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733

G

toll-like receptor 5

severity

DNA:nonsense mutation:cds:p.R392X (human)

RGD

NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738

G

tumor necrosis factor

mRNA:increased expression:urinary bladder

RGD

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

Diabetic Cystopathy

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

apoptosis inducing factor, mitochondria associated 1

protein:increased expression:nuclei:

RGD

NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256

G

BCL2-associated agonist of cell death

treatment

associated with Diabetes Mellitus, Experimental

RGD

NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823

G

caspase 12

associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:urinary bladder detrusor smooth muscle

RGD

NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037

female stress incontinence

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

regulator of G-protein signaling 2

RGD

NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385

hemorrhagic cystitis

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

glutathione-disulfide reductase

protein:increased activity:urinary bladder:

RGD

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

hypotonia-cystinuria syndrome

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

calmodulin-lysine N-methyltransferase

CTD Direct Evidence: marker/mechanism
OMIM:606407

NCBI chr 6:9,198,945...9,580,200
Ensembl chr 6:9,198,947...9,580,242

G

protein phosphatase, Mg2+/Mn2+ dependent, 1B

CTD Direct Evidence: marker/mechanism

NCBI chr 6:9,646,695...9,707,471
Ensembl chr 6:9,655,765...9,707,974

G

prolyl endopeptidase-like

CTD Direct Evidence: marker/mechanism

NCBI chr 6:9,580,367...9,609,957
Ensembl chr 6:9,580,217...9,607,772

G

solute carrier family 3 member 1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:9,608,169...9,641,881
Ensembl chr 6:9,608,178...9,641,907

interstitial cystitis

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adrenoceptor beta 2

susceptibility

DNA:polymorphism:cds:p.R16G (human)

RGD

NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512

G

allograft inflammatory factor 1

treatment

RGD

NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668

G

C-reactive protein

protein:increased expression:serum

RGD

NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178

G

colony stimulating factor 1

treatment

RGD

NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704

G

colony stimulating factor 2

protein:increased expression:urine

RGD

NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199

G

C-X-C motif chemokine ligand 10

CTD Direct Evidence: marker/mechanism

NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975

G

C-X-C motif chemokine ligand 11

CTD Direct Evidence: marker/mechanism

NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271

G

C-X-C motif chemokine ligand 9

CTD Direct Evidence: marker/mechanism

NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435

G

erb-b2 receptor tyrosine kinase 2

disease_progression

RGD

NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078

G

erb-b2 receptor tyrosine kinase 4

disease_progression

RGD

NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595

G

estrogen receptor 2

RGD

NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919

G

mitogen activated protein kinase 14

treatment

RGD

NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589

G

marker of proliferation Ki-67

RGD

NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762

G

mechanistic target of rapamycin kinase

RGD

NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311

G

nerve growth factor

treatment

protein:increased expression:serum, urine

RGD

PMID:23028581 PMID:18162370 PMID:20227820

RGD:7242773, RGD:7242805, RGD:7242781

NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452

G

nitric oxide synthase 2

protein:increased expression:bladder

RGD

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

G

neuregulin 1

disease_progression

RGD

NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884

G

tumor necrosis factor

treatment

RGD

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

vascular cell adhesion molecule 1

protein:increased expression:bladder, urine

RGD

NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958

neurogenic bladder

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

calcium voltage-gated channel subunit alpha1 A

ClinVar Annotator: match by term: Neurogenic bladder

PMID:25741868 PMID:26467025 PMID:28492532

NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225

G

cholinergic receptor, muscarinic 2

CTD Direct Evidence: therapeutic

NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103

G

EBF transcription factor 3

ClinVar Annotator: match by term: Neurogenic bladder

PMID:28017373 PMID:32366537 PMID:33956416

NCBI chr 1:191,996,726...192,114,593
Ensembl chr 1:191,996,730...192,114,359

G

nerve growth factor

treatment

associated with Meningomyelocele;protein:increased expression:urine
associated with Spinal Cord Injuries

RGD

PMID:23301927 PMID:22220508

RGD:7242771, RGD:7242776

NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452

overactive bladder syndrome

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adenylate cyclase activating polypeptide 1

CTD Direct Evidence: therapeutic

NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773

G

bradykinin receptor B1

RGD

NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747

G

CD40 ligand

protein:increased expression:urine

RGD

NCBI chr X:135,127,052...135,138,768
Ensembl chr X:135,126,969...135,138,306

G

C-reactive protein

protein:increased expression:serum

RGD

NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178

G

endothelin 1

CTD Direct Evidence: marker/mechanism

NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885

G

gap junction protein, alpha 1

mRNA:increased expression:urinary bladder

RGD

NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582

G

gap junction protein, alpha 5

mRNA:increased expression:urinary bladder

RGD

NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952

G

nerve growth factor

treatment

associated with Hypertension
CTD Direct Evidence: marker/mechanism
associated with Cystitis
associated with Cystitis;protein:increased expression:urine
protein:increased expression:serum

CTD
RGD

PMID:16600756 PMID:22473863 PMID:17050722 PMID:21605172 PMID:21717507 More...

RGD:7242775, RGD:7242798, RGD:7242780, RGD:7242779, RGD:7242778

NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452

G

NAD(P)H quinone dehydrogenase 1

treatment

associated with Spinal Cord Injuries

RGD

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

G

neuregulin 1

treatment

RGD

NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884

G

proenkephalin

treatment

RGD

NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129

G

transient receptor potential cation channel, subfamily A, member 1

CTD Direct Evidence: marker/mechanism|therapeutic

CTD
RGD

PMID:21367919 PMID:23523557 PMID:21367919

NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570

renal coloboma syndrome

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

hypoxia inducible factor 1 subunit alpha inhibitor

ClinVar Annotator: match by term: Renal coloboma syndrome

PMID:11461952 PMID:24676634 PMID:28492532

NCBI chr 1:243,419,175...243,440,464
Ensembl chr 1:243,419,194...243,434,327

G

NADH:ubiquinone oxidoreductase subunit B8

ClinVar Annotator: match by term: Renal coloboma syndrome

PMID:11461952 PMID:24676634 PMID:28492532

NCBI chr 1:243,408,656...243,413,715
Ensembl chr 1:243,408,619...243,413,817

G

paired box 2

ClinVar Annotator: match by term: Papillorenal syndrome with macular abnormalities | ClinVar Annotator: match by term: Renal coloboma syndrome
OMIM:120330
CTD Direct Evidence: marker/mechanism

OMIM
ClinVar
MouseDO
CTD

PMID:2644560 PMID:3377002 PMID:7795640 PMID:8589702 PMID:8943028 More...

NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321

urinary bladder cancer

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acetylcholinesterase

CTD Direct Evidence: marker/mechanism

NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651

G

AKT serine/threonine kinase 1

disease_progression

protein:increased expression:urinary bladder
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:36115647 PMID:18190825

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

arachidonate 12-lipoxygenase, 12S type

protein:increased expression:urinary bladder

RGD

NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542

G

alpha-methylacyl-CoA racemase

severity

RGD

NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255

G

autocrine motility factor receptor

CTD Direct Evidence: marker/mechanism

NCBI chr19:10,996,705...11,032,260
Ensembl chr19:10,996,099...11,032,247

G

angiogenin

protein:increased expression:plasma
protein:increased expression:urine

RGD

PMID:15912517 PMID:15329320

RGD:2325700, RGD:2325704

NCBI chr15:24,312,711...24,323,361

G

ankyrin repeat and FYVE domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:57,312,246...57,383,964
Ensembl chr10:57,312,246...57,383,964

G

alanyl aminopeptidase, membrane

CTD Direct Evidence: marker/mechanism

NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789

G

apurinic/apyrimidinic endodeoxyribonuclease 1

susceptibility

RGD

NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785

G

aquaporin 3 (Gill blood group)

CTD Direct Evidence: marker/mechanism

NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720

G

amphiregulin

disease_progression

mRNA:increased expression:urinary bladder

RGD

PMID:11507076 PMID:11133810

RGD:2292661, RGD:2292662

NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535

G

AT-rich interaction domain 1A

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malignant tumor of urinary bladder

PMID:21822268 PMID:25741868 PMID:32888375 PMID:34942405

NCBI chr 5:145,908,173...145,981,552
Ensembl chr 5:145,908,181...145,985,564

G

arsenite methyltransferase

CTD Direct Evidence: marker/mechanism

PMID:22747749 PMID:29669044 PMID:29859237 PMID:32539094

NCBI chr 1:245,595,939...245,628,921
Ensembl chr 1:245,596,108...245,627,872

G

ArfGAP with SH3 domain, ankyrin repeat and PH domain 1

CTD Direct Evidence: marker/mechanism

NCBI chr 7:95,786,130...96,093,111
Ensembl chr 7:95,787,818...96,092,754

G

ASXL transcriptional regulator 2

CTD Direct Evidence: marker/mechanism

NCBI chr 6:26,425,017...26,514,899
Ensembl chr 6:26,425,954...26,507,477

G

ATM serine/threonine kinase

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malignant tumor of urinary bladder

PMID:8755918 PMID:9043869 PMID:9450874 PMID:9463314 PMID:9497252 More...

NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437

G

ATP synthase F1 subunit delta

CTD Direct Evidence: marker/mechanism

NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929

G

ATP synthase membrane subunit c locus 2

DNA:hypermethylation:promoter

RGD

NCBI chr 7:133,791,341...133,799,713
Ensembl chr 7:133,791,342...133,799,733

G

aurora kinase A

disease_progression

mRNA, protein:increased expression:urinary bladder

RGD

NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390

G

axin 1

susceptibility

DNA:SNPs:5'utr: (rs12921862, rs1805105, rs370681) (human)

RGD

NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615

G

BRCA1 associated deubiquitinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535

G

BCL2 associated X, apoptosis regulator

RGD

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

BCL2, apoptosis regulator

severity

DNA:hypermethylation:promoter
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:36115647 PMID:18094410 PMID:18342927

RGD:2293014, RGD:2292910

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

Bcl2-like 1

disease_progression

RGD

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479

G

baculoviral IAP repeat-containing 3

CTD Direct Evidence: marker/mechanism

NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802

G

baculoviral IAP repeat-containing 5

disease_progression

protein:increased expression:urinary bladder

RGD

PMID:17905101 PMID:18089718

RGD:2293096, RGD:2293094

NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380

G

bromodomain PHD finger transcription factor

CTD Direct Evidence: marker/mechanism

NCBI chr10:91,980,279...92,082,731
Ensembl chr10:91,982,758...92,082,769

G

BRCA1, DNA repair associated

DNA:hypermethylation:promoter
ClinVar Annotator: match by term: Bladder cancer | ClinVar Annotator: match by term: Malignant tumor of urinary bladder

PMID:7894493 PMID:8460636 PMID:8554067 PMID:8968102 PMID:9150154 More...

NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304

G

BRCA2, DNA repair associated

ClinVar Annotator: match by term: Malignant tumor of urinary bladder

PMID:2673801 PMID:8673091 PMID:8896551 PMID:8988179 PMID:9150172 More...

NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567

G

similar to human chromosome 11 open reading frame 65

ClinVar Annotator: match by term: Malignant tumor of urinary bladder

PMID:8755918 PMID:9450874 PMID:9463314 PMID:9497252 PMID:9733514 More...

NCBI chr 8:53,796,033...53,825,277
Ensembl chr 8:53,796,366...53,824,748

G

calcium homeostasis modulator 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:246,030,269...246,032,988
Ensembl chr 1:246,030,269...246,032,988

G

carbonic anhydrase 9

disease_progression

RGD

NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838

G

caspase 3

disease_progression

RGD

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 9

susceptibility
disease_progression

DNA:polymorphism, deletion: :1263A>G, 293del (human)
DNA:SNP:exon:p.Q221R (rs1052576) (human)

RGD

PMID:19412632 PMID:19252927

RGD:2315929, RGD:2315930

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

G

catalase

CTD Direct Evidence: marker/mechanism

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

caveolin 1

severity

protein:increased expression:urinary bladder

RGD

NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705

G

chromobox 7

severity

mRNA:decreased expression:urinary bladder (human)

RGD

NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973

G

cyclin D1

protein:increased expression:bladder
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:36115647 PMID:12372886

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

cyclin D3

disease_progression

RGD

NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371

G

cyclin E1

severity
disease_progression

protein:decreased expression:urinary bladder
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:20972438 PMID:27514407 PMID:16739882 PMID:18047954

RGD:2289267, RGD:2296035

NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101

G

cyclin G1

mRNA:decreased expression:bladder (human)

RGD

NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641

G

CD40 ligand

treatment

RGD

NCBI chr X:135,127,052...135,138,768
Ensembl chr X:135,126,969...135,138,306

G

CD44 molecule

RGD

NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620

G

Cd82 molecule

disease_progression

protein:decreased expression:urinary bladder

RGD

PMID:14706010 PMID:17290345

RGD:2289401, RGD:2289391

NCBI chr 3:79,387,361...79,431,847
Ensembl chr 3:79,385,887...79,431,809

G

CD9 molecule

disease_progression

RGD

NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222

G

cell division cycle 25A

RGD

NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701

G

cell division cycle 25B

disease_progression

RGD

NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272

G

cadherin 1

disease_progression

protein:decreased expression:urinary bladder
CTD Direct Evidence: marker/mechanism
Protein:increased expression:cytoplasm

CTD
RGD

PMID:17520682 PMID:26901067 PMID:17760743 PMID:17167984

RGD:2289491, RGD:1599549

NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775

G

cadherin 13

DNA:hypermethylation:promoter

RGD

NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459

G

cyclin-dependent kinase 1

RGD

NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408

G

cyclin-dependent kinase 4

disease_progression

protein:increased expression:urinary bladder
DNA:amplification

RGD

PMID:16896691 PMID:11971182

RGD:2289144, RGD:2299056

NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase inhibitor 1A

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malignant tumor of urinary bladder

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1B

susceptibility
disease_progression

RGD

PMID:18027869 PMID:18334837

RGD:2293595, RGD:2293592

NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982

G

cyclin-dependent kinase inhibitor 2A

DNA:hypermethylation:promoter
ClinVar Annotator: match by term: Bladder cancer | ClinVar Annotator: match by term: Malignant tumor of urinary bladder
CTD Direct Evidence: marker/mechanism|therapeutic
DNA:deletion
protein:increased expression:urinary bladder

ClinVar
CTD
RGD

PMID:7777061 PMID:7987387 PMID:8668202 PMID:8755727 PMID:8834170 More...

RGD:2296052, RGD:2289687, RGD:2296048

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

G

cyclin-dependent kinase inhibitor 2A, variant 1

DNA:deletion

RGD

G

cyclin-dependent kinase inhibitor 2B

disease_progression

DNA:deletion:urinary bladder

RGD

PMID:15590562 PMID:16624482

RGD:2289696, RGD:7248757

NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050

G

chromodomain helicase DNA binding protein 6

CTD Direct Evidence: marker/mechanism

NCBI chr 3:149,596,509...149,757,765
Ensembl chr 3:149,596,509...149,757,755

G

checkpoint kinase 2

susceptibility
treatment

DNA:mutations: :multiple

RGD

PMID:17918154 PMID:21396995

RGD:2289704, RGD:10401655

NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286

G

CLPTM1-like

CTD Direct Evidence: marker/mechanism

NCBI chr 1:29,667,545...29,683,530
Ensembl chr 1:29,667,545...29,683,530

G

collagen type VI alpha 3 chain

mRNA, protein:increased expression:bladder (human)

RGD

NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471

G

catechol-O-methyltransferase

protein:increased expression:urinary bladder, urine

RGD

NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642

G

CREB binding protein

CTD Direct Evidence: marker/mechanism

NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888

G

colony stimulating factor 3

CTD Direct Evidence: therapeutic

PMID:7525883 PMID:17515069

NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603

G

catenin alpha 1

disease_progression

RGD

NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910

G

catenin alpha 3

ClinVar Annotator: match by term: Malignant tumor of urinary bladder

NCBI chr20:23,614,469...25,200,026
Ensembl chr20:23,623,560...25,199,978

G

catenin beta 1

disease_progression

ClinVar Annotator: match by term: Bladder cancer | ClinVar Annotator: match by term: Malignant tumor of urinary bladder
OMIM:109800

ClinVar
MouseDO
RGD

PMID:10192393 PMID:10666372 PMID:25157968 PMID:26619011 PMID:26822237 More...

NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111

G

cathepsin B

protein:increased activity:transitional cell carcinoma (human)

RGD

NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500

G

C-X-C motif chemokine receptor 2

DNA:SNP

RGD

NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425

G

cytochrome P450, family 17, subfamily a, polypeptide 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573

G

cytochrome P450, family 19, subfamily a, polypeptide 1

RGD

NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758

G

cytochrome P450, family 1, subfamily a, polypeptide 1

no_association

DNA:polymorphisms: :3801T>C (human)
DNA:polymorphism: :2455A>G (human)

RGD

PMID:21990318 PMID:18200441 PMID:18979064

RGD:7257730, RGD:7257736, RGD:7257733

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily b, polypeptide 1

RGD

NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917

G

cytochrome P450, subfamily 2, polypeptide 11

RGD

NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066

G

cytochrome P450, family 4, subfamily b, polypeptide 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348

G

death associated protein kinase 1

DNA:hypermethylation

RGD

NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991

G

DNA methyltransferase 1

protein:increased expression (in humans)

RGD

NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659

G

dual specificity phosphatase 1

disease_progression

RGD

NCBI chr10:16,680,478...16,683,275

G

E2F transcription factor 1

disease_progression

mRNA:increased expression:bladder

RGD

NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361

G

eukaryotic translation elongation factor 1 epsilon 1

disease_progression

protein:decreased expression:urothelium:

RGD

NCBI chr17:26,148,652...26,159,358
Ensembl chr17:26,148,633...26,215,720

G

epidermal growth factor receptor

disease_progression

protein:increased expression:urinary bladder
ClinVar Annotator: match by term: Malignant tumor of urinary bladder
CTD Direct Evidence: marker/mechanism

ClinVar
CTD
RGD

PMID:11723127 PMID:23523951 PMID:28492532 PMID:18006009 PMID:16685269

RGD:2289943, RGD:2298502

NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382

G

enolase 2

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:22613180 PMID:17951193

NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980

G

eomesodermin

CTD Direct Evidence: marker/mechanism

NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316

G

E1A binding protein p300

CTD Direct Evidence: marker/mechanism

NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088

G

epoxide hydrolase 1

disease_progression

DNA:SNPs

RGD

NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235

G

erb-b2 receptor tyrosine kinase 2

disease_progression

ClinVar Annotator: match by term: Malignant tumor of urinary bladder
CTD Direct Evidence: marker/mechanism

ClinVar
CTD
RGD

PMID:22908275 PMID:34291863 PMID:16685269 PMID:16771730

RGD:2298502, RGD:2289934

NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078

G

erb-b2 receptor tyrosine kinase 3

disease_progression

ClinVar Annotator: match by term: Bladder cancer | ClinVar Annotator: match by term: Malignant tumor of urinary bladder

PMID:26619011 PMID:16685269

NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525

G

erb-b2 receptor tyrosine kinase 4

disease_progression

protein:decreased expression:urinary bladder

RGD

PMID:18006009 PMID:16685269

RGD:2289943, RGD:2298502

NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595

G

ERCC excision repair 2, TFIIH core complex helicase subunit

disease_progression

ClinVar Annotator: match by term: Malignant tumor of urinary bladder
CTD Direct Evidence: marker/mechanism

ClinVar
CTD
RGD

PMID:9238033 PMID:11335038 PMID:19085937 PMID:19934020 PMID:24121791 More...

NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102

G

ERCC excision repair 4, endonuclease catalytic subunit

CTD Direct Evidence: marker/mechanism

NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369

G

extra spindle pole bodies like 1, separase

CTD Direct Evidence: marker/mechanism

NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984

G

estrogen receptor 1

CTD Direct Evidence: marker/mechanism

PMID:16712894 PMID:35764155

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

estrogen receptor 2

severity

protein:increased expression:urinary bladder urothelium (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:16700038 PMID:23612777

NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

mRNA:increased expression:urinary bladder

RGD

NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362

G

coagulation factor II, thrombin

severity

protein:increased expression:urine

RGD

NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486

G

FA complementation group A

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:24121791 PMID:19237606

NCBI chr19:51,304,126...51,362,586
Ensembl chr19:51,304,021...51,362,527

G

Fas cell surface death receptor

susceptibility

DNA:polymorphisms:promoter:-1377G>A,-670A>G
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:9070496 PMID:16538171

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

G

Fas ligand

susceptibility

DNA:polymorphisms:promoter:-844T>C

RGD

NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215

G

F-box and WD repeat domain containing 8

CTD Direct Evidence: marker/mechanism

NCBI chr12:38,426,466...38,517,076
Ensembl chr12:38,426,444...38,516,424

G

FERM domain containing kindlin 2

CTD Direct Evidence: marker/mechanism

NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811

G

fibroblast growth factor 1

RGD

NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357

G

fibroblast growth factor 2

RGD

NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221

G

fibroblast growth factor receptor 2

DNA:hypermethylation, loss of heterozygosity, deletions:exon (human)
associated with Acrocephalosyndactylia (MeSH:D000168)

RGD

PMID:10602477 PMID:16969861

RGD:2301193, RGD:2289664

NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626

G

fibroblast growth factor receptor 3

severity
disease_progression

DNA:mutations
ClinVar Annotator: match by term: Bladder cancer | ClinVar Annotator: match by term: Malignant tumor of urinary bladder | ClinVar Annotator: match by term: Urinary bladder cancer
CTD Direct Evidence: marker/mechanism
protein:increased expression:urinary bladder

ClinVar
CTD
OMIM
RGD

PMID:1908846 PMID:7647778 PMID:7649548 PMID:7670477 PMID:7702086 More...

RGD:2301223, RGD:2301224, RGD:2301225, RGD:2301222, RGD:2289864

NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341

G

fragile histidine triad diadenosine triphosphatase

protein:decreased expression:urinary bladder
associated with Schistosomiasis;DNA:hypermethylation:urinary bladder

RGD

PMID:15591090 PMID:11751381 PMID:15154012

RGD:2301232, RGD:2289897, RGD:2301233

NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340

G

fibronectin 1

protein:increased expression:urine

RGD

NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678

G

gamma-glutamyl hydrolase

CTD Direct Evidence: marker/mechanism

NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:33,529,880...33,552,787

G

GLI family zinc finger 1

CTD Direct Evidence: marker/mechanism

NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251

G

glutathione peroxidase 1

CTD Direct Evidence: marker/mechanism

PMID:15247771 PMID:35764155

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

glycogen synthase kinase 3 beta

CTD Direct Evidence: marker/mechanism

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

G

glutathione S-transferase mu 1

susceptibility

DNA:deletion: : (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:18505952 PMID:20972438 PMID:18544563

NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411

G

glutathione S-transferase omega 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:246,731,314...246,757,592
Ensembl chr 1:246,732,089...246,753,866

G

glutathione S-transferase pi 1

CTD Direct Evidence: marker/mechanism
mRNA:increased expression:urinary bladder

CTD
RGD

PMID:7729958 PMID:12500666 PMID:22306368 PMID:18544563 PMID:21213404 More...

RGD:6906879, RGD:10401939, RGD:6906883

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

glutathione S-transferase theta 1

susceptibility

DNA:deletion: : (human)

RGD

NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585

G

glutathione S-transferase zeta 1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284

G

H19 imprinted maternally expressed transcript

DNA:hypomethylation
DNA:SNP
mRNA:increased expression:urinary bladder

RGD

PMID:18950807 PMID:11726548 PMID:18262338 PMID:9886562

RGD:2306168, RGD:2306180, RGD:2306171, RGD:2306184

NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134

G

histone deacetylase 4

CTD Direct Evidence: marker/mechanism

NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164

G

hypoxia inducible factor 1 subunit alpha

CTD Direct Evidence: marker/mechanism

NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261

G

hexokinase 1

treatment

RGD

NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131

G

hydroxymethylbilane synthase

urinary bladder transitional cell carcinoma; mRNA:decreased expression:tumor:in matched malignant and non-malignant sample pairs (p = 0.008) (human)

RGD

NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957

G

high mobility group box 3

CTD Direct Evidence: marker/mechanism

NCBI chr X:149,296,303...149,301,290
Ensembl chr X:149,296,375...149,301,292

G

high mobility group nucleosome binding domain 5

CTD Direct Evidence: marker/mechanism

NCBI chr X:74,085,871...74,094,488
Ensembl chr X:74,085,875...74,094,441

G

homeobox A9

CTD Direct Evidence: marker/mechanism

NCBI chr 4:81,323,235...81,329,344
Ensembl chr 4:81,323,382...81,326,358

G

HRas proto-oncogene, GTPase

disease_progression

ClinVar Annotator: match by term: Bladder cancer | ClinVar Annotator: match by term: Urinary bladder cancer
CTD Direct Evidence: marker/mechanism

ClinVar
CTD
OMIM
RGD

PMID:2228319 PMID:2278634 PMID:2999610 PMID:3537694 PMID:6092966 More...

RGD:2314833, RGD:11060144

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

G

heat shock protein family A (Hsp70) member 1A

treatment

RGD

NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227

G

intercellular adhesion molecule 1

protein:increased expression:serum:

RGD

NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438

G

interferon beta 1

CTD Direct Evidence: therapeutic

NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523

G

interferon gamma

treatment

protein:decreased expression:serum

RGD

PMID:22906662 PMID:11219496

RGD:6893349, RGD:8157619

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

insulin-like growth factor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor binding protein 3

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:21347663 PMID:12544349

NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083

G

insulin-like growth factor binding protein 5

CTD Direct Evidence: marker/mechanism

NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156

G

immunoglobin superfamily, member 21

CTD Direct Evidence: marker/mechanism

NCBI chr 5:152,287,834...152,512,174
Ensembl chr 5:152,287,835...152,512,174

G

interleukin 1 beta

disease_progression

mRNA:increased expression:urinary bladder tumor (human)

RGD

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 1 receptor antagonist

susceptibility

DNA:repeats:intron:IVS2+914_1000dup IL1RN*2 (human)
DNA:repeats:intron:IVS2+914_1000dup multiple (human)

RGD

PMID:19489682 PMID:16698387

RGD:6907081, RGD:6907367

NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445

G

interleukin 2

treatment

CTD Direct Evidence: therapeutic

CTD
RGD

PMID:1949363 PMID:3495671 PMID:3262172

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

inositol polyphosphate-4-phosphatase type II B

CTD Direct Evidence: marker/mechanism

NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634

G

ISL LIM homeobox 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584

G

Janus kinase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

G

junction plakoglobin

disease_progression
severity

DNA, protein:mutations, increased expression:urinary bladder
protein:altered localization:tumor:loss of membrane expression associated with higher grade (p<0.05), higher stage (p<0.05), and poor survival (p<0.05)

PMID:9783980 PMID:11585741 PMID:17363521

RGD:2291880, RGD:2301748, RGD:2289818

NCBI chr10:85,300,438...85,327,378
Ensembl chr10:85,300,440...85,327,057

G

potassium inwardly-rectifying channel, subfamily J, member 12

CTD Direct Evidence: marker/mechanism

NCBI chr10:45,696,621...45,745,528
Ensembl chr10:45,696,849...45,745,492

G

lysine demethylase 4A

mRNA:increased expression:urinary bladder (human)

RGD

NCBI chr 5:131,672,754...131,719,534
Ensembl chr 5:131,672,754...131,719,501

G

lysine demethylase 4B

mRNA, protein:increased expression:urinary bladder (human)

RGD

NCBI chr 9:1,158,737...1,237,233
Ensembl chr 9:1,158,752...1,236,543

G

lysine demethylase 5B

mRNA:increased expression:urinary bladder (human)

RGD

NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872

G

lysine demethylase 6A

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malignant tumor of urinary bladder

PMID:21822268 PMID:23076834 PMID:23913813 PMID:25741868 PMID:27777708 More...

NCBI chr X:4,337,466...4,477,100
Ensembl chr X:4,337,750...4,477,062

G

kinase insert domain receptor

severity

RGD

PMID:12940780 PMID:12215294

RGD:2291949, RGD:2301758

NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018

G

KiSS-1 metastasis-suppressor

RGD

NCBI chr13:44,775,106...44,780,707
Ensembl chr13:44,774,823...44,780,612

G

KIT proto-oncogene receptor tyrosine kinase

urinary bladder small cell carcinoma

RGD

NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652

G

KLF transcription factor 5

CTD Direct Evidence: marker/mechanism

NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445

G

lysine methyltransferase 2A

CTD Direct Evidence: marker/mechanism

NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181

G

lysine methyltransferase 2C

CTD Direct Evidence: marker/mechanism

NCBI chr 4:9,620,638...9,834,787
Ensembl chr 4:9,609,627...9,833,539

G

lysine methyltransferase 2D

CTD Direct Evidence: marker/mechanism

NCBI chr 7:129,980,744...130,022,088
Ensembl chr 7:129,962,887...130,020,325

G

KRAS proto-oncogene, GTPase

transitional cell bladder carcinoma, OMIM:109800
ClinVar Annotator: match by term: Bladder cancer | ClinVar Annotator: match by term: Bladder cancer, transitional cell, somatic | ClinVar Annotator: match by term: Urinary bladder cancer
CTD Direct Evidence: marker/mechanism

ClinVar
CTD
OMIM
RGD

PMID:1553789 PMID:6695174 PMID:12110640 PMID:12460918 PMID:14982869 More...

NCBI chr 4:178,185,418...178,218,484

G

keratin 16

CTD Direct Evidence: marker/mechanism

NCBI chr10:85,168,357...85,171,816
Ensembl chr10:85,066,802...85,171,799

G

keratin 5

RGD

NCBI chr 7:132,846,132...132,851,861
Ensembl chr 7:132,846,136...132,851,850

G

laminin subunit alpha 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:17,672,675...18,320,641
Ensembl chr 1:17,672,536...18,320,530

G

DNA ligase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:74,165,688...74,204,400
Ensembl chr 1:74,165,842...74,204,413

G

lysyl oxidase-like 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:58,691,763...58,716,365
Ensembl chr 8:58,692,593...58,716,356

G

lysyl oxidase-like 4

CTD Direct Evidence: marker/mechanism

NCBI chr 1:241,396,183...241,416,385
Ensembl chr 1:241,397,983...241,416,322

G

leucine rich repeat containing 56

ClinVar Annotator: match by term: Bladder cancer | ClinVar Annotator: match by term: Malignant tumor of urinary bladder | ClinVar Annotator: match by term: Urinary bladder cancer

PMID:2999610 PMID:3537694 PMID:6092966 PMID:6330729 PMID:7177195 More...

NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172

G

MAGE family member A9

CTD Direct Evidence: marker/mechanism

NCBI chr X:142,619,282...142,624,654
Ensembl chr X:142,619,395...142,624,653

G

mitogen activated protein kinase kinase 4

RGD

NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993

G

mitogen activated protein kinase kinase 7

mRNA:splice variant:exon 2: (human)

RGD

NCBI chr12:2,591,312...2,600,534
Ensembl chr12:2,591,219...2,604,222

G

mitogen-activated protein kinase 15

CTD Direct Evidence: marker/mechanism

NCBI chr 7:107,694,907...107,714,640
Ensembl chr 7:107,694,964...107,714,645

G

MDM2 proto-oncogene

severity

mRNA:increased expression:bladder

RGD

NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915

G

O-6-methylguanine-DNA methyltransferase

susceptibility

DNA:polymorphisms:cds:p.L53L, p.L84F (human)

RGD

NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756

G

microRNA 100

CTD Direct Evidence: marker/mechanism

NCBI chr 8:41,901,225...41,901,304
Ensembl chr 8:41,901,225...41,901,304

G

microRNA 132

CTD Direct Evidence: marker/mechanism

NCBI chr10:60,023,696...60,023,796
Ensembl chr10:60,023,696...60,023,796

G

microRNA 145

CTD Direct Evidence: marker/mechanism

NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727

G

microRNA 152

severity

miRNA:decreased expression:urinary bladder

RGD

NCBI chr10:81,832,936...81,833,020
Ensembl chr10:81,832,936...81,833,020

G

microRNA 186

CTD Direct Evidence: marker/mechanism

NCBI chr 2:246,582,806...246,582,891
Ensembl chr 2:246,582,806...246,582,891

G

microRNA 193b

CTD Direct Evidence: marker/mechanism

NCBI chr10:1,317,742...1,317,824
Ensembl chr10:1,317,742...1,317,824

G

microRNA 221

CTD Direct Evidence: marker/mechanism

NCBI chr X:3,429,465...3,429,573
Ensembl chr X:3,429,465...3,429,573

G

microRNA 27a

CTD Direct Evidence: marker/mechanism

NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917

G

microRNA 34b

CTD Direct Evidence: marker/mechanism

NCBI chr 8:51,410,244...51,410,327
Ensembl chr 8:51,410,244...51,410,327

G

microRNA 494

ameliorates

RGD

NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793

G

microRNA 532

CTD Direct Evidence: marker/mechanism

NCBI chr X:15,247,315...15,247,393
Ensembl chr X:15,247,315...15,247,393

G

microRNA 93

CTD Direct Evidence: marker/mechanism

NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221

G

microRNA 99a

CTD Direct Evidence: marker/mechanism

NCBI chr11:16,200,443...16,200,523
Ensembl chr11:16,200,443...16,200,523

G

marker of proliferation Ki-67

protein:increased expression:urinary bladder

RGD

NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762

G

mutL homolog 1

disease_progression

RGD

NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617

G

matrix metallopeptidase 1

severity

DNA:insertion:promoter:g.-1607insG (human)
protein:increased expression:urine (human)

RGD

PMID:17986285 PMID:11705862

RGD:7207077, RGD:7207140

NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097

G

matrix metallopeptidase 13

urinary bladder transitional-cell carcinomas

RGD

NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239

G

matrix metallopeptidase 2

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:30548095 PMID:17466450

NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870

G

matrix metallopeptidase 9

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:30548095 PMID:17466450

NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120

G

myeloperoxidase

CTD Direct Evidence: marker/mechanism

NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819

G

MRE11 homolog, double strand break repair nuclease

susceptibility

DNA:snp:3' utr:c.2501A>G rs2155209 (human)
ClinVar Annotator: match by term: Malignant tumor of urinary bladder

PMID:28492532 PMID:18638378

NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279

G

mutS homolog 2

disease_progression

DNA:mutation
DNA:mutations: :multiple
associated with Lynch syndrome
protein:decreased expression:urinary bladder

RGD

PMID:18389386 PMID:26385421 PMID:22883484 PMID:18254781

RGD:2293502, RGD:126790580, RGD:126790557, RGD:2293503

NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938

G

mutS homolog 6

disease_progression

protein:decreased expression:urinary bladder

NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956

G

mitochondrially encoded ATP synthase membrane subunit 8

DNA:deletion: :(human)

RGD

NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961

G

mitochondrially encoded cytochrome b

DNA:deletion:cds

RGD

NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2

DNA:deletion: :(human)

RGD

NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942

G

metallothionein 1

CTD Direct Evidence: marker/mechanism

NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049

G

metallothionein 2A

CTD Direct Evidence: marker/mechanism

PMID:7729958 PMID:16565513

NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784

G

metallothionein 3

CTD Direct Evidence: marker/mechanism

NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158

G

methylenetetrahydrofolate reductase

susceptibility
no_association

DNA:transition:cds:g.677C>T (human)
CTD Direct Evidence: marker/mechanism
protein:missense mutation:cds:p.A222V (human)
DNA:transversion:cds:g.1298A>C (human)
DNA:transition, transversion, haplotype:cds:g.677C>T, g.1298A>C (human)

CTD
RGD

PMID:22747749 PMID:22126575 PMID:17311259 PMID:19837268 PMID:20146887

RGD:6893457, RGD:6893597, RGD:6893521, RGD:6893516

NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797

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mechanistic target of rapamycin kinase

treatment

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:36115647 PMID:19261747

NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311

G

5-methyltetrahydrofolate-homocysteine methyltransferase

susceptibility

DNA:polymorphism: :2756A>G(human)

RGD

NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822

G

mucin 1, cell surface associated

protein:increased expression:serum:

RGD

NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733

G

mucin 5B, oligomeric mucus/gel-forming

DNA:repeats

RGD

NCBI chr 1:196,916,861...196,948,830
Ensembl chr 1:196,916,825...196,949,250

G

MYC proto-oncogene, bHLH transcription factor

susceptibility
disease_progression

DNA:snp, haplotype:enhancer:g.-30772G>T rs9642880 (human)
CTD Direct Evidence: marker/mechanism
protein:decreased expression:urinary bladder urothelium (human)

CTD
RGD

PMID:2228319 PMID:23284801 PMID:20939013 PMID:22028816

RGD:7207401, RGD:7207427, RGD:7207418

NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630

G

N-acetyltransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:22,218,217...22,238,516
Ensembl chr16:22,208,194...22,238,520

G

N-acetyltransferase 2

susceptibility

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:10022756 PMID:15717312 PMID:18505952 PMID:20972438 PMID:24221535 More...

NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520

G

neurocan

CTD Direct Evidence: marker/mechanism

NCBI chr16:19,301,969...19,328,436
Ensembl chr16:19,301,969...19,328,436

G

nuclear receptor co-repressor 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032

G

nicastrin

OMIM:109800

NCBI chr13:84,530,442...84,546,454
Ensembl chr13:84,530,440...84,546,454

G

nectin cell adhesion molecule 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360

G

NEDD4 E3 ubiquitin protein ligase

RGD

NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951

G

neurofibromin 1

ClinVar Annotator: match by term: Bladder cancer | ClinVar Annotator: match by term: Malignant tumor of urinary bladder

PMID:8069310 PMID:10090487 PMID:10712197 PMID:10862084 PMID:10980545 More...

NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658

G

NME/NM23 nucleoside diphosphate kinase 1

mRNA:increased expression:urinary bladder

RGD

NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408

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NME/NM23 nucleoside diphosphate kinase 2

mRNA:increased expression:urinary bladder

RGD

NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538

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nitric oxide synthase 3

protein:increased expression:urinary bladder

RGD

NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166

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NAD(P)H quinone dehydrogenase 1

treatment

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:8631603 PMID:21213404

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

G

neurensin 1

CTD Direct Evidence: marker/mechanism

NCBI chr17:39,806,238...39,824,550
Ensembl chr17:39,806,238...39,823,813

G

olfactory receptor family 8 subfamily S member 5

CTD Direct Evidence: marker/mechanism

NCBI chr 7:129,490,113...129,491,030
Ensembl chr 7:129,486,292...129,496,949

G

poly(A) binding protein, cytoplasmic 1

CTD Direct Evidence: marker/mechanism

NCBI chr 7:67,777,438...67,789,731
Ensembl chr 7:67,777,381...67,789,744

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prohibitin 1

mRNA:increased expression:urinary bladder

RGD

NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042

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phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

ClinVar Annotator: match by term: Malignant tumor of urinary bladder

NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032

G

phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha

CTD Direct Evidence: marker/mechanism

NCBI chr 2:182,628,299...182,671,584
Ensembl chr 2:182,628,300...182,671,598

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plasminogen activator, urokinase

treatment

protein:increased expression:urinary bladder (human)
DNA:snp:3' utr:g.4065C>T (human)

RGD

PMID:19010488 PMID:18336603 PMID:16825821

RGD:4144867, RGD:7241213, RGD:7241144

NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775

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polo-like kinase 1

severity

RGD

PMID:16837776 PMID:15761500

RGD:2299938, RGD:2299940

NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400

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polyamine-modulated factor 1

disease_progression

RGD

NCBI chr 2:173,848,074...173,868,272
Ensembl chr 2:173,848,074...173,868,270

G

PMS1 homolog 2, mismatch repair system component

susceptibility

DNA:SNP: :rs6463524 (human)

RGD

NCBI chr12:10,676,818...10,701,161
Ensembl chr12:10,676,764...10,701,066

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DNA polymerase beta

CTD Direct Evidence: marker/mechanism

NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812

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paraoxonase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360

G

cytochrome p450 oxidoreductase

CTD Direct Evidence: marker/mechanism

NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245

G

peroxisome proliferator-activated receptor gamma

protein:decreased expression:urinary bladder

RGD

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

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protein phosphatase 3 catalytic subunit gamma

CTD Direct Evidence: marker/mechanism

NCBI chr15:45,289,917...45,362,012
Ensembl chr15:45,290,373...45,361,832

G

PR/SET domain 2

CTD Direct Evidence: marker/mechanism

NCBI chr 5:155,421,066...155,531,884
Ensembl chr 5:155,422,134...155,531,825

G

protein kinase C, alpha

severity
disease_progression

protein:increased expression:urinary bladder
protein:altered localization:urinary bladder

RGD

PMID:16008942 PMID:15922420

RGD:2292455, RGD:2298669

NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012

G

serine protease 3

CTD Direct Evidence: marker/mechanism

NCBI chr 4:70,203,088...70,206,562
Ensembl chr 4:70,203,088...70,206,562

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prostate stem cell antigen

CTD Direct Evidence: marker/mechanism

PMID:19648920 PMID:20083643

NCBI chr 7:106,598,203...106,603,114
Ensembl chr 7:106,595,284...106,609,746

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proteasome 20S subunit beta 2

CTD Direct Evidence: marker/mechanism

NCBI chr 5:138,970,564...139,002,715
Ensembl chr 5:138,970,533...139,021,137

G

phosphatase and tensin homolog

disease_progression

DNA:mutations: :multiple
ClinVar Annotator: match by term: Malignant tumor of urinary bladder
OMIM:109800
protein:decreased expression:urinary bladder

ClinVar
MouseDO
RGD

PMID:9140396 PMID:9256433 PMID:9735393 PMID:9811831 PMID:10051603 More...

RGD:2292515, RGD:2291891

NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838

G

prostaglandin-endoperoxide synthase 2

disease_progression
susceptibility

CTD Direct Evidence: marker/mechanism
DNA:SNP:3' utr:837T>C (human)

CTD
RGD

PMID:10582676 PMID:10873095 PMID:12442003 PMID:12664575 PMID:16098373 More...

RGD:2300200, RGD:5508302, RGD:2300127

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

RAB27A, member RAS oncogene family

CTD Direct Evidence: marker/mechanism

NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829

G

RAB27B, member RAS oncogene family

CTD Direct Evidence: marker/mechanism

NCBI chr18:63,597,554...63,794,124
Ensembl chr18:63,600,937...63,757,180

G

ralA binding protein 1

mRNA, protein:increased expression:urinary bladder

RGD

NCBI chr 9:105,456,425...105,493,235
Ensembl chr 9:105,456,425...105,492,707

G

Ral GEF with PH domain and SH3 binding motif 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:16,433,323...16,670,276
Ensembl chr 3:16,433,742...16,669,972

G

Ras association domain family member 1

DNA:hypermethylation
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:15987713 PMID:18702824 PMID:12222680

RGD:2299860, RGD:2291977

NCBI chr 8:108,225,023...108,236,164
Ensembl chr 8:108,225,023...108,236,164

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RB transcriptional corepressor 1

disease_progression

ClinVar Annotator: match by term: Bladder cancer | ClinVar Annotator: match by term: Malignant tumor of urinary bladder | ClinVar Annotator: match by term: Urinary bladder cancer
CTD Direct Evidence: marker/mechanism

ClinVar
CTD
OMIM
RGD

PMID:1352883 PMID:2181449 PMID:2601691 PMID:7704558 PMID:7881418 More...

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

G

RELA proto-oncogene, NF-kB subunit

disease_progression

RGD

PMID:18188593 PMID:18089718

RGD:2298753, RGD:2293094

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

resistin

protein:increased expression:urine

RGD

NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620

G

ras homolog family member A

disease_progression

protein:increased expression:urinary bladder
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:19896475 PMID:12855641

NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746

G

ribonucleotide reductase regulatory subunit M2

mRNA:increased expression:bladder (rat)

RGD

NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773

G

RUNX family transcription factor 3

DNA:hypermethylation:promoter

RGD

NCBI chr 5:147,360,587...147,419,161
Ensembl chr 5:147,360,994...147,419,156

G

S100 calcium binding protein A8

mRNA:increased expression:urinary bladder

RGD

NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643

G

S100 calcium binding protein A9

mRNA:increased expression:urinary bladder

RGD

NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230

G

S100 calcium binding protein B

mRNA:increased expression:urinary bladder urothelium

RGD

NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743

G

serpin family E member 1

RGD

NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657

G

stratifin

disease_progression

protein:increased expression:urothelium (human)

RGD

NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314

G

solute carrier family 11 member 1

disease_progression

DNA:repeat, polymorphism:promoter, cds:p.D543N (human)

RGD

NCBI chr 9:75,957,193...75,968,115
Ensembl chr 9:75,957,316...75,968,101

G

solute carrier family 12 member 7

CTD Direct Evidence: marker/mechanism

NCBI chr 1:29,472,692...29,554,246
Ensembl chr 1:29,472,692...29,554,302

G

solute carrier family 19 member 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:11,584,410...11,602,429
Ensembl chr20:11,584,411...11,601,972

G

SMAD family member 2

RGD

NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323

G

SMAD family member 4

protein:decreased expression:urinary bladder

RGD

NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438

G

structural maintenance of chromosomes 1A

CTD Direct Evidence: marker/mechanism

NCBI chr X:21,103,323...21,148,053
Ensembl chr X:21,103,282...21,148,056

G

structural maintenance of chromosomes 1B

CTD Direct Evidence: marker/mechanism

NCBI chr 7:116,180,987...116,242,778
Ensembl chr 7:116,180,987...116,242,744

G

suppressor of cytokine signaling 1

disease_progression

DNA:hypermethylation:promoter

RGD

PMID:16242928 PMID:17522834

RGD:2298906, RGD:2298903

NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383

G

superoxide dismutase 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249

G

superoxide dismutase 2

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:14729580 PMID:18930813 PMID:17974967

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

G

SRY-box transcription factor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338

G

SRY-box transcription factor 4

RGD

NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665

G

secreted protein acidic and cysteine rich

disease_progression

RGD

PMID:11696817 PMID:17149610

RGD:2300024, RGD:2300021

NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396

G

serine peptidase inhibitor, Kazal type 1

disease_progression

mRNA, protein:decreased expression:urinary bladder

RGD

NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642

G

secreted phosphoprotein 1

RGD

NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162

G

SRC proto-oncogene, non-receptor tyrosine kinase

CTD Direct Evidence: marker/mechanism

PMID:11723127 PMID:17093206

NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476

G

serine and arginine rich splicing factor 9

mRNA:increased expression:urinary bladder epithelium (human)

RGD

NCBI chr12:41,278,225...41,284,502
Ensembl chr12:41,275,687...41,284,499

G

STAG2 cohesin complex component

CTD Direct Evidence: marker/mechanism

PMID:24121789 PMID:24121791 PMID:24121792

NCBI chr X:120,974,687...121,105,677
Ensembl chr X:120,974,857...121,105,677

G

signal transducer and activator of transcription 3

CTD Direct Evidence: marker/mechanism

NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057

G

sulfotransferase family 1A member 1

RGD

NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562

G

transforming, acidic coiled-coil containing protein 3

CTD Direct Evidence: marker/mechanism

NCBI chr14:77,051,209...77,065,343
Ensembl chr14:77,051,215...77,065,219

G

telomerase RNA component

disease_progression

RNA:increased expression:urinary bladder
RNA:increased expression:urine

RGD

PMID:16104909 PMID:17644139

RGD:2291967, RGD:2291986

NCBI chr 2:112,815,654...112,816,041

G

telomerase reverse transcriptase

protein:increased expression:urine
ClinVar Annotator: match by term: Malignant tumor of urinary bladder
CTD Direct Evidence: marker/mechanism

ClinVar
CTD
RGD

PMID:19151717 PMID:20871597 PMID:22037553 PMID:23066086 PMID:23348503 More...

NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561

G

trefoil factor 1

protein:increased expression:urinary bladder

RGD

NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597

G

transferrin receptor

CTD Direct Evidence: marker/mechanism

NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257

G

transforming growth factor, beta receptor 1

RGD

NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777

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thrombospondin 1

severity

protein:decreased expression:bladder

RGD

NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440

G

TIMP metallopeptidase inhibitor 2

disease_progression

protein:decreased expression:serum
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:30548095 PMID:17374529 PMID:17466450

RGD:2298521, RGD:2290395

NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611

G

TIMP metallopeptidase inhibitor 3

DNA:hypermethylation:promoter

RGD

NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839

G

toll-like receptor 2

DNA:deletion:promoter:−196_−174del (human)

RGD

NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630

G

toll-like receptor 4

treatment

RGD

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

G

transmembrane protein with EGF-like and two follistatin-like domains 2

DNA:hypermethylation:promoter

RGD

NCBI chr 9:50,445,947...50,733,473
Ensembl chr 9:50,436,079...50,733,475

G

tumor necrosis factor

CTD Direct Evidence: therapeutic

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

TNF receptor superfamily member 10b

DNA:missense mutation:cds:p.E228A (c.683A>C) (human)

RGD

NCBI chr15:44,840,386...44,868,318
Ensembl chr15:44,840,386...44,867,467

G

DNA topoisomerase II alpha

disease_progression

RGD

NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874

G

tumor protein p53

disease_progression

protein:increased expression:urinary bladder
ClinVar Annotator: match by term: Bladder cancer | ClinVar Annotator: match by term: Malignant tumor of urinary bladder
CTD Direct Evidence: marker/mechanism

ClinVar
CTD
RGD

PMID:224644 PMID:1565143 PMID:1591732 PMID:1631151 PMID:1683921 More...

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

G

tumor protein p63

disease_progression

RGD

NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398

G

tumor protein p73

disease_progression

mRNA:increased expression:urinary bladder

RGD

NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128

G

transient receptor potential cation channel, subfamily V, member 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513

G

TSC complex subunit 1

ClinVar Annotator: match by term: Bladder cancer | ClinVar Annotator: match by term: Malignant tumor of urinary bladder

PMID:9242607 PMID:9328481 PMID:9803264 PMID:9863590 PMID:9924605 More...

NCBI chr 3:11,969,547...12,018,591
Ensembl chr 3:11,979,729...12,015,674

G

thymidine phosphorylase

disease_progression

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:11103787 PMID:15841086 PMID:16937303

NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874
Ensembl chr 7:120,438,770...120,443,874

G

thymidylate synthetase

RGD

NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536

G

ubiquitin-conjugating enzyme E2I

radiation-induced dysplasia and carcinoma in situ; protein:increased expression:bladder urothelium:increased in Chernobyl victims vs controls from uncontaminated areas of the Ukraine (p<0.001) (human)

RGD

NCBI chr10:14,277,749...14,294,681
Ensembl chr10:69,701,618...69,702,443
Ensembl chr10:69,701,618...69,702,443

G

UDP glucuronosyltransferase family 2 member B7

CTD Direct Evidence: marker/mechanism

NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604

G

ubiquitin specific peptidase 7

CTD Direct Evidence: marker/mechanism

NCBI chr10:6,880,684...6,925,355
Ensembl chr10:6,828,795...6,925,355

G

vascular endothelial growth factor A

mRNA:increased expression:bladder

RGD

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

G

vascular endothelial growth factor C

disease_progression

RGD

NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848

G

vascular endothelial growth factor D

disease_progression

RGD

NCBI chr X:30,073,122...30,108,413
Ensembl chr X:30,074,163...30,108,295

G

von Hippel-Lindau tumor suppressor

mRNA:decreased expression:urinary bladder

RGD

NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377

G

von Willebrand factor A domain containing 3A

CTD Direct Evidence: marker/mechanism

NCBI chr 1:175,293,782...175,355,588
Ensembl chr 1:175,293,873...175,355,602

G

Wnt inhibitory factor 1

disease_progression

protein:decreased expression:urinary bladder
DNA:hypermethylation:promoter

RGD

PMID:14517837 PMID:18325051

RGD:727214, RGD:2291868

NCBI chr 7:56,548,060...56,618,364
Ensembl chr 7:56,548,053...56,618,360

G

Wnt family member 7B

superficial, NOT invasive

RGD

NCBI chr 7:116,634,817...116,679,459
Ensembl chr 7:116,634,814...116,679,581

G

xanthine dehydrogenase

protein:decreased activity:urinary bladder

RGD

NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268

G

X-ray repair cross complementing 1

susceptibility
no_association

DNA:polymorphism: :p.R399Q
DNA:SNP: p.R399Q (human)
DNA:polymorphisms: :multiple

RGD

PMID:18765423 PMID:18272472 PMID:17425776

RGD:2302568, RGD:150530493, RGD:2302572

NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701

G

YjeF N-terminal domain containing 3

CTD Direct Evidence: marker/mechanism

NCBI chr16:19,533,742...19,539,759
Ensembl chr16:19,533,788...19,539,728

G

zinc finger protein 609

CTD Direct Evidence: marker/mechanism

NCBI chr 8:66,214,553...66,349,319
Ensembl chr 8:66,214,555...66,317,977

Urinary Bladder Neoplasm

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

AT-rich interaction domain 1A

ClinVar Annotator: match by term: Urinary Bladder Neoplasms

PMID:25741868 PMID:32888375 PMID:34942405

NCBI chr 5:145,908,173...145,981,552
Ensembl chr 5:145,908,181...145,985,564

G

BRCA1, DNA repair associated

ClinVar Annotator: match by term: Urinary Bladder Neoplasms

PMID:7894493 PMID:9150154 PMID:10227398 PMID:11802209 PMID:12402341 More...

NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304

G

BRCA2, DNA repair associated

ClinVar Annotator: match by term: Urinary Bladder Neoplasms

PMID:17924331 PMID:18607349 PMID:19043619 PMID:19200354 PMID:19563646 More...

NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567

G

cyclin-dependent kinase inhibitor 2A

ClinVar Annotator: match by term: Urinary Bladder Neoplasms

PMID:7777061 PMID:8668202 PMID:8755727 PMID:8834170 PMID:9660926 More...

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

G

catenin beta 1

ClinVar Annotator: match by term: Urinary Bladder Neoplasms

PMID:10192393 PMID:10666372 PMID:26619011 PMID:26822237

NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111

G

erb-b2 receptor tyrosine kinase 3

ClinVar Annotator: match by term: Urinary Bladder Neoplasms

NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525

G

fibroblast growth factor receptor 3

ClinVar Annotator: match by term: Urinary Bladder Neoplasms

PMID:1908846 PMID:7647778 PMID:7649548 PMID:7670477 PMID:7702086 More...

NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341

G

HRas proto-oncogene, GTPase

ClinVar Annotator: match by term: Urinary Bladder Neoplasms

PMID:2999610 PMID:3537694 PMID:6092966 PMID:6330729 PMID:7177195 More...

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

G

KRAS proto-oncogene, GTPase

ClinVar Annotator: match by term: Urinary Bladder Neoplasms

PMID:6695174 PMID:12110640 PMID:12460918 PMID:14982869 PMID:15696205 More...

NCBI chr 4:178,185,418...178,218,484

G

leucine rich repeat containing 56

ClinVar Annotator: match by term: Urinary Bladder Neoplasms

PMID:2999610 PMID:3537694 PMID:6092966 PMID:6330729 PMID:7177195 More...

NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172

G

neurofibromin 1

ClinVar Annotator: match by term: Urinary Bladder Neoplasms

PMID:10712197 PMID:16835897 PMID:16944272 PMID:23913538 PMID:25074460 More...

NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658

G

RB transcriptional corepressor 1

ClinVar Annotator: match by term: Urinary Bladder Neoplasms

PMID:1352883 PMID:7881418 PMID:9632788 PMID:9671401 PMID:10486322 More...

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

G

tumor protein p53

ClinVar Annotator: match by term: Urinary Bladder Neoplasms

PMID:1565143 PMID:1591732 PMID:1631151 PMID:1683921 PMID:1978757 More...

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

G

TSC complex subunit 1

ClinVar Annotator: match by term: Urinary Bladder Neoplasms

PMID:9328481 PMID:9803264 PMID:9863590 PMID:9924605 PMID:10227394 More...

NCBI chr 3:11,969,547...12,018,591
Ensembl chr 3:11,979,729...12,015,674

Urinary Bladder Reperfusion Injury

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

elastase, neutrophil expressed

treatment

RGD

NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100

urinary schistosomiasis

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

CD1d1 molecule

protein:increased expression:B cell (human)

RGD

NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089

G

cytotoxic T-lymphocyte-associated protein 4

susceptibility

DNA:SNPs:multiple:Gabonese(human)

RGD

NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963

G

interleukin 5

resistance

RGD

NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213

G

signal transducer and activator of transcription 6

severity

DNA:SNP:enhancer: (rs324013)

RGD

NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495

vesicoureteral reflux

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

actin filament associated protein 1-like 2

ClinVar Annotator: match by term: Vesicoureteral reflux

NCBI chr 1:255,964,238...256,060,828
Ensembl chr 1:255,964,238...256,060,820

G

angiotensin II receptor, type 1a

RGD

NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946

G

angiotensin II receptor, type 2

no_association

DNA:transition:intron:-1332A>G (human)

RGD

PMID:12187255 PMID:15470205 PMID:11819209

RGD:6903860, RGD:6903853, RGD:6903866

NCBI chr X:112,119,876...112,124,060
Ensembl chr X:112,120,228...112,124,057

G

colony stimulating factor 1

RGD

NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704

G

hepatitis A virus cellular receptor 1

RGD

NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698

G

interferon gamma

DNA:polymorphism: : 874T>A (human)

RGD

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

insulin-like growth factor 1 receptor

RGD

NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777

G

lysine acetyltransferase 6B

ClinVar Annotator: match by term: Vesico-Ureteral Reflux

NCBI chr15:2,638,885...2,811,977
Ensembl chr15:2,639,200...2,812,316

G

mediator complex subunit 13L

ClinVar Annotator: match by term: Vesico-Ureteral Reflux

NCBI chr12:37,807,596...38,004,886
Ensembl chr12:37,808,285...38,004,473

G

roundabout guidance receptor 2

ClinVar Annotator: match by term: Vesicoureteral reflux

NCBI chr11:12,528,949...14,096,726
Ensembl chr11:12,528,951...13,041,536

G

SRY-box transcription factor 17

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Vesicoureteral reflux

NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228

G

tenascin XB

CTD Direct Evidence: marker/mechanism

G

uroplakin 3A

OMIM:193000 | OMIM:314550 | OMIM:610878 | OMIM:613674 | OMIM:614317 | OMIM:614318 | OMIM:614319 | OMIM:614674 | OMIM:615390 | OMIM:615963

NCBI chr 7:116,128,981...116,139,950
Ensembl chr 7:116,134,874...116,139,948

G

von Willebrand factor A domain containing 2

ClinVar Annotator: match by term: Vesicoureteral reflux

NCBI chr 1:255,922,263...255,963,920
Ensembl chr 1:255,923,541...255,963,934

Vesicoureteral Reflux 2

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

roundabout guidance receptor 2

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: ROBO2-related condition | ClinVar Annotator: match by term: Vesicoureteral reflux 2

OMIM
CTD
ClinVar

PMID:16199547 PMID:17357069 PMID:18235093 PMID:22558067 PMID:22995991 More...

NCBI chr11:12,528,949...14,096,726
Ensembl chr11:12,528,951...13,041,536

Vesicoureteral Reflux 3

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

SRY-box transcription factor 17

ClinVar Annotator: match by term: SOX17-related condition | ClinVar Annotator: match by term: Vesicoureteral reflux 3

PMID:20960469 PMID:25741868 PMID:28492532 PMID:28566479

NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228

Vesicoureteral Reflux 5

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

reticulophagy regulator 1

Neuropathy, sensory, RETREG1-related

PMID:6295050 PMID:15971901 PMID:16266014 PMID:23123885 PMID:27527794 More...

NCBI chr 2:76,335,609...76,474,817
Ensembl chr 2:76,335,609...76,493,898

Vesicoureteral Reflux 8

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

tenascin XB

ClinVar Annotator: match by term: TNXB-related condition | ClinVar Annotator: match by term: Vesicoureteral reflux 8

PMID:9288108 PMID:11642233 PMID:15733269 PMID:16199547 PMID:20853426 More...

Term paths to the root

Path 1
Term	Annotations
disease	19072
disease of anatomical entity	18365
Urogenital Diseases	5279
urinary system disease	2851
bladder disease	448
Cystocele +	0
Diabetic Cystopathy	3
Panic Disorder with Bladder Conditions	0
Urinary Bladder Fistula +	0
Urinary Bladder Neoplasm +	307
Urinary Bladder Reperfusion Injury	1
bladder calculus +	1
bladder diverticulum +	1
bladder exstrophy	2
bladder fermentation syndrome	0
bladder neck obstruction	13
bladder tuberculosis	0
congenital megabladder	1
cystinuria +	7
cystitis +	49
detrusor sphincter dyssynergia	0
female stress incontinence	1
low compliance bladder	0
neurogenic bladder +	5
overactive bladder syndrome	12
pelvic lipomatosis +	0
urinary schistosomiasis	4
vesicoureteral reflux +	70

paths to the root