Greb1l (GREB1 like retinoic acid receptor coactivator) - Rat Genome Database

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Gene: Greb1l (GREB1 like retinoic acid receptor coactivator) Rattus norvegicus
Analyze
Symbol: Greb1l
Name: GREB1 like retinoic acid receptor coactivator
RGD ID: 1562371
Description: Predicted to be involved in animal organ development and paramesonephric duct development. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in renal agenesis. Orthologous to human GREB1L (GREB1 like retinoic acid receptor coactivator); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine; 3',5'-cyclic AMP.
Type: protein-coding
RefSeq Status: MODEL
Also known as: growth regulation by estrogen in breast cancer 1 like; growth regulation by estrogen in breast cancer-like; LOC498819; RGD1562371; similar to GREB1 protein isoform a
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2181,392,330 - 1,629,483 (+)NCBI
Rnor_6.0 Ensembl181,723,565 - 1,784,233 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0181,537,315 - 1,784,260 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0181,704,334 - 1,742,157 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0181,757,633 - 1,821,402 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4181,795,820 - 1,908,522 (+)NCBIRGSC3.4rn4RGSC3.4
Celera181,273,512 - 1,511,753 (+)NCBICelera
Cytogenetic Map18p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

Additional References at PubMed
PMID:29100090   PMID:29100091  


Genomics

Comparative Map Data
Greb1l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2181,392,330 - 1,629,483 (+)NCBI
Rnor_6.0 Ensembl181,723,565 - 1,784,233 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0181,537,315 - 1,784,260 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0181,704,334 - 1,742,157 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0181,757,633 - 1,821,402 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4181,795,820 - 1,908,522 (+)NCBIRGSC3.4rn4RGSC3.4
Celera181,273,512 - 1,511,753 (+)NCBICelera
Cytogenetic Map18p13NCBI
GREB1L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1821,242,242 - 21,525,417 (+)EnsemblGRCh38hg38GRCh38
GRCh381821,242,225 - 21,528,503 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371818,822,193 - 19,106,073 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361817,076,317 - 17,356,789 (+)NCBINCBI36hg18NCBI36
Build 341817,076,200 - 17,342,674NCBI
Celera1815,628,176 - 15,908,773 (+)NCBI
Cytogenetic Map18q11.1-q11.2NCBI
HuRef1815,669,485 - 15,949,616 (+)NCBIHuRef
CHM1_11818,749,282 - 19,029,843 (+)NCBICHM1_1
Greb1l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391810,324,933 - 10,562,945 (+)NCBIGRCm39mm39
GRCm39 Ensembl1810,325,177 - 10,562,940 (+)Ensembl
GRCm381810,324,933 - 10,562,945 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1810,325,177 - 10,562,940 (+)EnsemblGRCm38mm10GRCm38
MGSCv371810,325,177 - 10,562,939 (+)NCBIGRCm37mm9NCBIm37
MGSCv361810,325,175 - 10,562,939 (+)NCBImm8
MGSCv361810,327,252 - 10,429,003 (+)NCBImm8
Celera1810,354,956 - 10,592,831 (+)NCBICelera
Cytogenetic Map18A1NCBI
Greb1l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540210,104,225 - 10,201,479 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554029,865,934 - 10,204,990 (+)NCBIChiLan1.0ChiLan1.0
GREB1L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11818,120,919 - 18,402,948 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1818,244,575 - 18,400,335 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01814,482,493 - 14,763,789 (+)NCBIMhudiblu_PPA_v0panPan3
GREB1L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1766,489,124 - 66,758,207 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl766,503,999 - 66,639,013 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha765,943,213 - 66,212,115 (-)NCBI
ROS_Cfam_1.0766,553,669 - 66,823,094 (-)NCBI
UMICH_Zoey_3.1766,231,940 - 66,488,010 (-)NCBI
UNSW_CanFamBas_1.0766,242,907 - 66,511,844 (-)NCBI
UU_Cfam_GSD_1.0766,544,142 - 66,813,301 (-)NCBI
Greb1l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494462,574,871 - 62,832,489 (-)NCBI
SpeTri2.0NW_0049365501,110,679 - 1,240,463 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GREB1L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6106,419,943 - 106,691,646 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16106,545,882 - 106,693,711 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2698,943,800 - 99,199,449 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GREB1L
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11858,960,397 - 59,104,188 (-)NCBI
ChlSab1.1 Ensembl1858,963,914 - 59,103,993 (-)Ensembl
Greb1l
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477010,223,131 - 10,471,309 (-)NCBI

Position Markers
RH131132  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0181,685,936 - 1,686,155NCBIRnor6.0
Rnor_5.0181,731,947 - 1,732,166UniSTSRnor5.0
RGSC_v3.4181,818,161 - 1,818,380UniSTSRGSC3.4
Celera181,421,558 - 1,421,777UniSTS
RH 3.4 Map1810.3UniSTS
Cytogenetic Map18p13UniSTS
RH131955  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0181,753,708 - 1,753,927NCBIRnor6.0
Rnor_5.0181,787,681 - 1,787,900UniSTSRnor5.0
Celera181,478,108 - 1,478,327UniSTS
RH 3.4 Map1810.3UniSTS
Cytogenetic Map18p13UniSTS
AU047007  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0181,653,242 - 1,653,389NCBIRnor6.0
Rnor_5.0181,699,253 - 1,699,400UniSTSRnor5.0
RGSC_v3.4181,784,411 - 1,784,558UniSTSRGSC3.4
Celera181,388,726 - 1,388,873UniSTS
Cytogenetic Map18p13UniSTS
RH138057  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0181,785,660 - 1,785,868NCBIRnor6.0
Rnor_5.0181,819,633 - 1,819,841UniSTSRnor5.0
RGSC_v3.4181,931,159 - 1,931,367UniSTSRGSC3.4
Celera181,509,984 - 1,510,192UniSTS
RH 3.4 Map1812.5UniSTS
Cytogenetic Map18p13UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590248Scort10Serum corticosterone level QTL 1019.710.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)18125999214Rat
8552968Pigfal19Plasma insulin-like growth factor 1 level QTL 1911.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)18125999214Rat
61388Bp2Blood pressure QTL 23.23arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)18135097280Rat
2300180Bmd67Bone mineral density QTL 674.80.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)18138195967Rat
2293661Bss50Bone structure and strength QTL 504.640.0003lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)18138195967Rat
9589153Insul31Insulin level QTL 317.150.05blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)18138753381Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:25
Count of miRNA genes:25
Interacting mature miRNAs:25
Transcripts:ENSRNOT00000033468
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 3 2 2 8 9
Low 34 53 38 19 38 8 8 66 35 32 11 8
Below cutoff 3 6 1 1 1 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000033468   ⟹   ENSRNOP00000029000
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl181,723,565 - 1,784,233 (+)Ensembl
RefSeq Acc Id: XM_017587815   ⟹   XP_017443304
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera181,273,514 - 1,511,753 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017587816   ⟹   XP_017443305
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera181,387,554 - 1,511,753 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017587817   ⟹   XP_017443306
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera181,273,516 - 1,511,753 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017587818   ⟹   XP_017443307
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera181,273,512 - 1,511,753 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017601152   ⟹   XP_017456641
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0181,537,315 - 1,784,260 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039097265   ⟹   XP_038953193
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2181,392,330 - 1,629,483 (+)NCBI
RefSeq Acc Id: XM_039097266   ⟹   XP_038953194
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2181,492,428 - 1,629,483 (+)NCBI
RefSeq Acc Id: XM_039097267   ⟹   XP_038953195
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2181,392,330 - 1,629,483 (+)NCBI
RefSeq Acc Id: XM_039097268   ⟹   XP_038953196
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2181,392,330 - 1,629,483 (+)NCBI
RefSeq Acc Id: XM_039097269   ⟹   XP_038953197
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2181,492,428 - 1,629,483 (+)NCBI
RefSeq Acc Id: XM_039097270   ⟹   XP_038953198
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2181,392,331 - 1,629,483 (+)NCBI
RefSeq Acc Id: XM_039097272   ⟹   XP_038953200
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2181,392,330 - 1,629,483 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_017443307   ⟸   XM_017587818
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017443304   ⟸   XM_017587815
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017443306   ⟸   XM_017587817
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017443305   ⟸   XM_017587816
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017456641   ⟸   XM_017601152
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000029000   ⟸   ENSRNOT00000033468
RefSeq Acc Id: XP_038953195   ⟸   XM_039097267
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038953196   ⟸   XM_039097268
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038953193   ⟸   XM_039097265
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038953200   ⟸   XM_039097272
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038953198   ⟸   XM_039097270
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038953197   ⟸   XM_039097269
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038953194   ⟸   XM_039097266
- Peptide Label: isoform X1

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562371 AgrOrtholog
Ensembl Genes ENSRNOG00000023492 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000029000 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000033468 UniProtKB/TrEMBL
InterPro GREB1 UniProtKB/TrEMBL
  GREB1-like UniProtKB/TrEMBL
NCBI Gene 498819 ENTREZGENE
PANTHER PTHR15720 UniProtKB/TrEMBL
  PTHR15720:SF12 UniProtKB/TrEMBL
Pfam GREB1 UniProtKB/TrEMBL
PhenoGen Greb1l PhenoGen
UniProt F1LTR0_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-04-04 Greb1l  GREB1 like retinoic acid receptor coactivator  Greb1l  growth regulation by estrogen in breast cancer 1 like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-06-22 Greb1l  growth regulation by estrogen in breast cancer 1 like  Greb1l  growth regulation by estrogen in breast cancer-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-25 Greb1l  growth regulation by estrogen in breast cancer-like  RGD1562371  similar to GREB1 protein isoform a  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1562371  similar to GREB1 protein isoform a   RGD1562371_predicted  similar to GREB1 protein isoform a (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1562371_predicted  similar to GREB1 protein isoform a (predicted)  LOC498819  similar to GREB1 protein isoform a  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498819  similar to GREB1 protein isoform a      Symbol and Name status set to provisional 70820 PROVISIONAL