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Gene: Prss3 (serine protease 3) Rattus norvegicus
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Symbol: Prss3
Name: serine protease 3
Description: Predicted to have calcium ion binding activity and serine-type endopeptidase activity. Predicted to be involved in endothelial cell migration and zymogen activation. Predicted to localize to the extracellular space. Human ortholog(s) of this gene implicated in pancreatitis. Orthologous to several human genes including PRSS3 (serine protease 3); PARTICIPATES IN influenza A pathway; INTERACTS WITH (RS)-amphetamine; 2,2',5,5'-tetrachlorobiphenyl; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC362347; protease, serine 3; protease, serine, 3 (mesotrypsin); similar to protease, serine, 3 (mesotrypsin); Try4; trypsin 4
Orthologs:
Homo sapiens (human) : PRSS3 (serine protease 3)  HGNC  Alliance
Mus musculus (house mouse) : Try4 (trypsin 4)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : PRSS3 (serine protease 3)
Canis lupus familiaris (dog) : PRSS2 (serine protease 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0470,614,524 - 70,617,998 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04135,405,339 - 135,408,813 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4469,011,939 - 69,015,413 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1469,288,070 - 69,291,540 (+)NCBI
Celera465,173,009 - 65,176,483 (+)NCBICelera
Cytogenetic Map4q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Prss3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311446
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.