Prss3 (serine protease 3) - Rat Genome Database

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Gene: Prss3 (serine protease 3) Rattus norvegicus
Analyze
Symbol: Prss3
Name: serine protease 3
RGD ID: 1311446
Description: Predicted to enable calcium ion binding activity and serine-type endopeptidase activity. Predicted to be involved in endothelial cell migration and zymogen activation. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in pancreatitis. Orthologous to several human genes including PRSS3P2 (PRSS3 pseudogene 2); PRSS1 (serine protease 1); and PRSS2 (serine protease 2); PARTICIPATES IN influenza A pathway; INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; acrylamide; amphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC362347; protease, serine 3; protease, serine, 3 (mesotrypsin); similar to protease, serine, 3 (mesotrypsin); Try4; trypsin 4
RGD Orthologs
Human
Mouse
Bonobo
Dog
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8471,169,749 - 71,173,223 (+)NCBIGRCr8
mRatBN7.2470,203,088 - 70,206,562 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl470,203,088 - 70,206,562 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx475,117,399 - 75,120,876 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0471,031,384 - 71,034,858 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0469,447,371 - 69,450,848 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0470,614,524 - 70,617,998 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl470,614,524 - 70,617,998 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04135,405,339 - 135,408,813 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4469,011,939 - 69,015,413 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1469,288,070 - 69,291,540 (+)NCBI
Celera465,173,009 - 65,176,483 (+)NCBICelera
Cytogenetic Map4q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:6698368   PMID:9099703   PMID:11827488   PMID:14507909   PMID:15313892   PMID:16903872   PMID:17623652   PMID:23376485  


Genomics

Comparative Map Data
Prss3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8471,169,749 - 71,173,223 (+)NCBIGRCr8
mRatBN7.2470,203,088 - 70,206,562 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl470,203,088 - 70,206,562 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx475,117,399 - 75,120,876 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0471,031,384 - 71,034,858 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0469,447,371 - 69,450,848 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0470,614,524 - 70,617,998 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl470,614,524 - 70,617,998 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04135,405,339 - 135,408,813 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4469,011,939 - 69,015,413 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1469,288,070 - 69,291,540 (+)NCBI
Celera465,173,009 - 65,176,483 (+)NCBICelera
Cytogenetic Map4q23NCBI
PRSS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38933,750,679 - 33,799,231 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl933,750,679 - 33,799,231 (+)EnsemblGRCh38hg38GRCh38
GRCh37933,750,677 - 33,799,229 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36933,785,559 - 33,789,228 (+)NCBINCBI36Build 36hg18NCBI36
Build 34933,785,558 - 33,789,228NCBI
Celera933,682,374 - 33,731,080 (+)NCBICelera
Cytogenetic Map9p13.3NCBI
HuRef933,708,415 - 33,757,154 (+)NCBIHuRef
CHM1_1933,750,270 - 33,799,034 (+)NCBICHM1_1
T2T-CHM13v2.0933,769,262 - 33,817,820 (+)NCBIT2T-CHM13v2.0
Try4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39641,279,206 - 41,282,467 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl641,279,203 - 41,282,466 (+)EnsemblGRCm39 Ensembl
GRCm38641,302,272 - 41,305,533 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl641,302,269 - 41,305,532 (+)EnsemblGRCm38mm10GRCm38
MGSCv37641,252,271 - 41,255,532 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36641,231,876 - 41,235,139 (+)NCBIMGSCv36mm8
Celera641,256,920 - 41,260,181 (+)NCBICelera
Cytogenetic Map6B1NCBI
cM Map619.41NCBI
PRSS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21190,802,768 - 90,851,190 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1990,808,710 - 90,857,132 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0933,589,522 - 33,637,991 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1934,401,323 - 34,449,666 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl934,401,323 - 34,449,666 (+)Ensemblpanpan1.1panPan2
PRSS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1166,778,109 - 6,781,404 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha167,636,741 - 7,640,085 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0166,698,975 - 6,702,319 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl166,698,970 - 6,702,925 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1166,652,160 - 6,655,505 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0166,494,056 - 6,497,400 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0166,562,480 - 6,565,824 (-)NCBIUU_Cfam_GSD_1.0

Variants

.
Variants in Prss3
36 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:123
Count of miRNA genes:90
Interacting mature miRNAs:93
Transcripts:ENSRNOT00000017852, ENSRNOT00000018042, ENSRNOT00000041100
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658103194791Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44043338885433388Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44345797688457976Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)457486946102486946Rat
61336Bp21Blood pressure QTL 214.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45711470578881294Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658115089733Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)42690728575585128Rat
61475Aia2Adjuvant induced arthritis QTL 25.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)43950527573892441Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44043341485433414Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)42949419581006281Rat
2317577Eae24Experimental allergic encephalomyelitis QTL 24nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)46699318572752834Rat
6909122Insul22Insulin level QTL 224.63blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)42690728575585128Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
2300179Bmd50Bone mineral density QTL 505.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)460928534105928534Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)462933508114921294Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)456647873149491524Rat
1578657Bss12Bone structure and strength QTL 128.9femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)460220938105220938Rat
1578658Bss13Bone structure and strength QTL 138femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)460220938105220938Rat
4889969Bss96Bone structure and strength QTL 964.9tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)45664777678882945Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
4889972Bss97Bone structure and strength QTL 975.6tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)45664777678882945Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
5685012Bmd87Bone mineral density QTL 875.1tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)45664777678882945Rat
5685009Bmd86Bone mineral density QTL 863.7tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)45664777678882945Rat
1331807Rf31Renal function QTL 312.988urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)43952426474726312Rat
8552782Vie1Viral induced encephalitis QTL 126.4brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
634311Sach7Saccharin preference QTL 7taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)45711443281266970Rat
2306547Iddm38Insulin dependent diabetes mellitus QTL 38blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)46738666970362197Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
2312569Pur19Proteinuria QTL 193.40.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)46588210796130297Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)436303261103194984Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
8552801Bw143Body weight QTL 1437.3body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)43443048482490359Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
8552807Vie4Viral induced encephalitis QTL 47.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)46293350882490359Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4521460278882945Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)462277855128289560Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)462879517107879517Rat
8552809Vie5Viral induced encephalitis QTL 525.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
1558651Swd3Spike wave discharge measurement QTL 34.620.000024brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)45843213392991462Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)456698790126192555Rat
631546Bp86Blood pressure QTL 863.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45711443291360801Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
7394826Bw126Body weight QTL 1260.002body mass (VT:0001259)body weight gain (CMO:0000420)46293326987483707Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat
631671Iddm11Insulin dependent diabetes mellitus QTL 113.60.0012blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)45863587778886137Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
4 2 3 9 18 21 8 22 8 1 45 29 4 2 12 13

Sequence


Ensembl Acc Id: ENSRNOT00000041100   ⟹   ENSRNOP00000039224
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl470,203,088 - 70,206,562 (+)Ensembl
Rnor_6.0 Ensembl470,614,524 - 70,617,998 (+)Ensembl
RefSeq Acc Id: NM_001108626   ⟹   NP_001102096
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8471,169,749 - 71,173,223 (+)NCBI
mRatBN7.2470,203,088 - 70,206,562 (+)NCBI
Rnor_6.0470,614,524 - 70,617,998 (+)NCBI
Rnor_5.04135,405,339 - 135,408,813 (+)NCBI
RGSC_v3.4469,011,939 - 69,015,413 (+)RGD
Celera465,173,009 - 65,176,483 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001102096 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM15461 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000039224.3
RefSeq Acc Id: NP_001102096   ⟸   NM_001108626
- Peptide Label: precursor
- UniProtKB: D3ZQV0 (UniProtKB/TrEMBL),   A6IF24 (UniProtKB/TrEMBL),   A6IF27 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000039224   ⟸   ENSRNOT00000041100
Protein Domains
Peptidase S1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZQV0-F1-model_v2 AlphaFold D3ZQV0 1-246 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692994
Promoter ID:EPDNEW_R3519
Type:single initiation site
Name:Prss3_1
Description:protease, serine 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0470,614,528 - 70,614,588EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311446 AgrOrtholog
BioCyc Gene G2FUF-45125 BioCyc
Ensembl Genes ENSRNOG00000031385 Ensembl
  ENSRNOG00000068192 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000041100.4 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
InterPro Peptidase_S1/S6_AS UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Peptidase_S1_S6 UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/TrEMBL
  Ser/Cys_Pept_Trypsin-like UniProtKB/TrEMBL
  Serine_Proteases_S1 UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
KEGG Report rno:362347 UniProtKB/TrEMBL
NCBI Gene 362347 ENTREZGENE
PANTHER PROTEASE, SERINE 1 (TRYPSIN 1)-RELATED UniProtKB/TrEMBL
  TRYPSIN-1 UniProtKB/TrEMBL
  TRYPSIN-RELATED UniProtKB/TrEMBL
Pfam Trypsin UniProtKB/TrEMBL
PhenoGen Prss3 PhenoGen
PRINTS CHYMOTRYPSIN UniProtKB/TrEMBL
PROSITE TRYPSIN_DOM UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
RatGTEx ENSRNOG00000031385 RatGTEx
  ENSRNOG00000068192 RatGTEx
SMART Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP Pept_Ser_Cys UniProtKB/TrEMBL
UniProt A6IF24 ENTREZGENE, UniProtKB/TrEMBL
  A6IF27 ENTREZGENE, UniProtKB/TrEMBL
  D3ZQV0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-01-26 Prss3  serine protease 3  Prss3  protease, serine 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-12-10 Prss3  protease, serine 3  Try4  trypsin 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-09-17 Try4  trypsin 4  LOC362347  similar to protease, serine, 3 (mesotrypsin)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 LOC362347  similar to protease, serine, 3 (mesotrypsin)   LOC362347_predicted  similar to protease, serine, 3 (mesotrypsin) (predicted)  'predicted' is removed 2292626 APPROVED
2007-09-25 LOC362347_predicted  similar to protease, serine, 3 (mesotrypsin) (predicted)  Prss3_predicted  protease, serine, 3 (mesotrypsin) (predicted)  Symbol and Name updated 1299863 PROVISIONAL
2005-01-12 Prss3_predicted  protease, serine, 3 (mesotrypsin) (predicted)      Symbol and Name status set to approved 70820 APPROVED