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Gene: Kmt2c (lysine methyltransferase 2C) Rattus norvegicus
Symbol: Kmt2c
Name: lysine methyltransferase 2C
RGD ID: 1587205
Description: Predicted to have histone methyltransferase activity (H3-K4 specific). Predicted to be involved in several processes, including eyelid development in camera-type eye; histone H3-K4 monomethylation; and positive regulation of fibroblast proliferation. Predicted to localize to MLL3/4 complex. Human ortholog(s) of this gene implicated in Kleefstra syndrome 2; esophagus squamous cell carcinoma; and squamous cell carcinoma. Orthologous to human KMT2C (lysine methyltransferase 2C); PARTICIPATES IN DNA modification pathway; histone modification pathway; INTERACTS WITH amphetamine; bisphenol A; dibutyl phthalate.
Type: protein-coding
RefSeq Status: MODEL
Also known as: histone-lysine N-methyltransferase 2C; LOC502710; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C; lysine (K)-specific methyltransferase 2C; myeloid/lymphoid or mixed-lineage leukemia 3-like; similar to Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3)
Homo sapiens (human) : KMT2C (lysine methyltransferase 2C)  HGNC  Alliance
Mus musculus (house mouse) : Kmt2c (lysine (K)-specific methyltransferase 2C)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kmt2c (lysine methyltransferase 2C)
Pan paniscus (bonobo/pygmy chimpanzee) : KMT2C (lysine methyltransferase 2C)
Canis lupus familiaris (dog) : KMT2C (lysine methyltransferase 2C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kmt2c (lysine methyltransferase 2C)
Sus scrofa (pig) : KMT2C (lysine methyltransferase 2C)
Chlorocebus sabaeus (African green monkey) : KMT2C (lysine methyltransferase 2C)
Heterocephalus glaber (naked mole-rat) : Kmt2c (lysine methyltransferase 2C)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0482,506 - 109,986 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.046,083,650 - 6,294,413 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl46,083,736 - 6,292,516 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0482,826 - 109,979 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.046,104,240 - 6,315,339 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.445,020,018 - 5,239,019 (+)NCBIRGSC3.4rn4RGSC3.4
Celera4484,949 - 698,981 (-)NCBICelera
Cytogenetic Map4q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Kmt2c
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1587205
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2020-11-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.