Kmt2c (lysine methyltransferase 2C) - Rat Genome Database

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Gene: Kmt2c (lysine methyltransferase 2C) Rattus norvegicus
Analyze
Symbol: Kmt2c
Name: lysine methyltransferase 2C
RGD ID: 1587205
Description: Predicted to enable histone H3K4 monomethyltransferase activity and transcription coactivator activity. Involved in response to electrical stimulus. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of MLL3/4 complex. Used to study rheumatoid arthritis. Human ortholog(s) of this gene implicated in Kleefstra syndrome 2; carcinoma (multiple); and stomach cancer. Orthologous to human KMT2C (lysine methyltransferase 2C); PARTICIPATES IN DNA modification pathway; histone modification pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: histone-lysine N-methyltransferase 2C; LOC502710; lysine (K)-specific methyltransferase 2C; myeloid/lymphoid or mixed-lineage leukemia 3-like; similar to Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8410,353,698 - 10,755,965 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl410,353,735 - 10,568,620 (+)EnsemblGRCr8
mRatBN7.249,620,638 - 9,834,787 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl49,609,627 - 9,833,539 (+)EnsemblmRatBN7.2
Rnor_6.0482,506 - 109,986 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.046,083,650 - 6,294,413 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl46,083,736 - 6,292,516 (+)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.0482,826 - 109,979 (+)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.046,104,240 - 6,315,339 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.445,020,018 - 5,239,019 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4484,949 - 698,981 (-)NCBICelera
Cytogenetic Map4q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
acute myeloid leukemia  (ISO)
adenocarcinoma  (ISO)
adenoid cystic carcinoma  (ISO)
autism spectrum disorder  (ISO)
autistic disorder  (ISO)
brachydactyly  (ISO)
Breast Cancer, Familial  (ISO)
breast carcinoma  (ISO)
Cafe-au-Lait Spots  (ISO)
cervical cancer  (ISO)
cervical dystonia  (ISO)
cholangiocarcinoma  (ISO)
clear cell renal cell carcinoma  (ISO)
cleft palate  (ISO)
colon adenocarcinoma  (ISO)
Craniosynostosis Syndrome, Autosomal Recessive  (ISO)
cystic lymphangioma  (ISO)
developmental and epileptic encephalopathy 92  (ISO)
Developmental Disabilities  (ISO)
disease of cellular proliferation  (ISO)
Dwarfism  (ISO)
early-onset dystonia and/or spastic paraplegia  (ISO)
Enuresis  (ISO)
epilepsy  (ISO)
esophageal cancer  (ISO)
esophagus squamous cell carcinoma  (ISO)
Familial Pancreatic Carcinoma  (ISO)
Familial Prostate Cancer  (ISO)
Funnel Chest  (ISO)
generalized epilepsy  (ISO)
genetic disease  (ISO)
head and neck squamous cell carcinoma  (ISO)
hepatocellular carcinoma  (ISO)
high grade glioma  (ISO)
Hypertelorism  (ISO)
intellectual disability  (ISO)
Klatskin's tumor  (ISO)
Kleefstra syndrome 2  (ISO)
Language Development Disorders  (ISO)
laryngeal carcinoma  (ISO)
laryngomalacia  (ISO)
learning disability  (ISO)
lung adenocarcinoma  (ISO)
lung cancer  (ISO)
lung non-small cell carcinoma  (ISO)
lung squamous cell carcinoma  (ISO)
medulloblastoma non-WNT/non-SHH group 3  (ISO)
medulloblastoma non-WNT/non-SHH group 4  (ISO)
medulloblastoma WNT activated  (ISO)
melanoma  (ISO)
meningioma  (ISO)
microcephaly  (ISO)
multiple myeloma  (ISO)
Muscle Hypotonia  (ISO)
nasopharynx carcinoma  (ISO)
Neurodevelopmental Disorders  (ISO)
nonpapillary renal cell carcinoma  (ISO)
obstructive sleep apnea  (ISO)
osteochondrodysplasia  (ISO)
ovarian serous cystadenocarcinoma  (ISO)
Parasitic Liver Diseases  (ISO)
Plagiocephaly  (ISO)
posterior fossa ependymoma  (ISO)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
Retrognathia  (ISO)
rheumatoid arthritis  (IMP)
sarcoma  (ISO)
sensorineural hearing loss  (ISO)
Sezary's disease  (ISO)
squamous cell carcinoma  (ISO)
stomach cancer  (ISO)
stomach carcinoma  (ISO)
Stomach Neoplasms  (ISO)
strabismus  (ISO)
syndactyly  (ISO)
syndromic intellectual disability  (ISO)
Talipes Cavus  (ISO)
thymoma  (ISO)
Thyroid Carcinoma, Nonmedullary 1  (ISO)
transitional cell carcinoma  (ISO)
urinary bladder cancer  (ISO)
uterine corpus endometrial carcinoma  (ISO)
Velopharyngeal Insufficiency  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
amphetamine  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
copper(II) sulfate  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
folic acid  (ISO)
FR900359  (ISO)
gallic acid  (ISO)
inulin  (ISO)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
Mecamylamine  (ISO)
methidathion  (ISO)
methimazole  (EXP)
nicotine  (ISO)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
potassium chromate  (ISO)
rac-lactic acid  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
tubocurarine  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. SPLUNC1 and MLL3 regulate cancer stem cells in nasopharyngeal carcinoma. Bian S, etal., J BUON. 2019 Jul-Aug;24(4):1700-1705.
2. Histone lysine methylation dynamics: establishment, regulation, and biological impact. Black JC, etal., Mol Cell. 2012 Nov 30;48(4):491-507. doi: 10.1016/j.molcel.2012.11.006.
3. H3K4 Methylation Status and Lysine Specific Methyltransferase KMT2C Expression Correlate with Prognosis in Lung Adenocarcinoma. Bosgana P, etal., Curr Mol Pharmacol. 2021;14(6):1028-1036. doi: 10.2174/1874467213999200831130739.
4. MLL3 Inhibits Apoptosis of Rheumatoid Arthritis Fibroblast-Like Synoviocytes and Promotes Secretion of Inflammatory Factors by Activating CCL2 and the NF-κB Pathway. Fan W, etal., Inflammation. 2021 Oct;44(5):1803-1814. doi: 10.1007/s10753-021-01459-2. Epub 2021 Apr 29.
5. Comprehensive analysis of genomic alterations of Chinese hilar cholangiocarcinoma patients. Feng F, etal., Int J Clin Oncol. 2021 Apr;26(4):717-727. doi: 10.1007/s10147-020-01846-z. Epub 2021 Jan 2.
6. Assessment of MLL methyltransferase gene expression in larynx carcinoma. Figueiredo DL, etal., Oncol Rep. 2015 Apr;33(4):2017-22. doi: 10.3892/or.2015.3756. Epub 2015 Jan 28.
7. Genetic landscape of esophageal squamous cell carcinoma. Gao YB, etal., Nat Genet. 2014 Oct;46(10):1097-102. doi: 10.1038/ng.3076. Epub 2014 Aug 24.
8. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
9. Genetic hallmarks of recurrent/metastatic adenoid cystic carcinoma. Ho AS, etal., J Clin Invest. 2019 Oct 1;129(10):4276-4289. doi: 10.1172/JCI128227.
10. Mll3 genetic variants affect risk of gastric cancer in the chinese han population. Li B, etal., Asian Pac J Cancer Prev. 2013;14(7):4239-42. doi: 10.7314/apjcp.2013.14.7.4239.
11. Association of MLL3 expression with prognosis in gastric cancer. Li B, etal., Genet Mol Res. 2014 Sep 12;13(3):7513-8. doi: 10.4238/2014.September.12.18.
12. A missense mutation (S3660L) in MLL3 gene influences risk of gastric cancer. Li B, etal., J BUON. 2014 Apr-Jun;19(2):394-7.
13. ZF-CxxC domain-containing proteins, CpG islands and the chromatin connection. Long HK, etal., Biochem Soc Trans. 2013 Jun;41(3):727-40. doi: 10.1042/BST20130028.
14. Genomic Analyses for Predictors of Response to Chemoradiation in Stage III Non-Small Cell Lung Cancer. Luo LY, etal., Adv Radiat Oncol. 2020 Nov 14;6(1):100615. doi: 10.1016/j.adro.2020.10.027. eCollection 2021 Jan-Feb.
15. Mutational landscape of aggressive cutaneous squamous cell carcinoma. Pickering CR, etal., Clin Cancer Res. 2014 Oct 10. pii: clincanres.1768.2014.
16. Acute and Chronic Electroconvulsive Seizures (ECS) Differentially Regulate the Expression of Epigenetic Machinery in the Adult Rat Hippocampus. Pusalkar M, etal., Int J Neuropsychopharmacol. 2016 Sep 21;19(9). pii: pyw040. doi: 10.1093/ijnp/pyw040. Print 2016 Sep.
17. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
18. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
19. Comprehensive gene review and curation RGD comprehensive gene curation
20. The COMPASS family of histone H3K4 methylases: mechanisms of regulation in development and disease pathogenesis. Shilatifard A Annu Rev Biochem. 2012;81:65-95. doi: 10.1146/annurev-biochem-051710-134100.
21. Deregulated expression of selected histone methylases and demethylases in prostate carcinoma. Vieira FQ, etal., Endocr Relat Cancer. 2013 Dec 16;21(1):51-61. doi: 10.1530/ERC-13-0375. Print 2014 Feb.
22. Comprehensive analysis of age-related somatic mutation profiles in Chinese young lung adenocarcinoma patients. Yang B, etal., Cancer Med. 2019 Apr;8(4):1350-1358. doi: 10.1002/cam4.1839. Epub 2019 Mar 1.
Additional References at PubMed
PMID:17021013   PMID:17500065   PMID:18172164   PMID:22266653   PMID:22658674   PMID:26324722  


Genomics

Comparative Map Data
Kmt2c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8410,353,698 - 10,755,965 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl410,353,735 - 10,568,620 (+)EnsemblGRCr8
mRatBN7.249,620,638 - 9,834,787 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl49,609,627 - 9,833,539 (+)EnsemblmRatBN7.2
Rnor_6.0482,506 - 109,986 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.046,083,650 - 6,294,413 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl46,083,736 - 6,292,516 (+)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.0482,826 - 109,979 (+)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.046,104,240 - 6,315,339 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.445,020,018 - 5,239,019 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4484,949 - 698,981 (-)NCBICelera
Cytogenetic Map4q11NCBI
KMT2C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387152,134,925 - 152,436,003 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7152,134,922 - 152,436,656 (-)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh377151,832,010 - 152,133,088 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367151,462,943 - 151,764,023 (-)NCBIBuild 36Build 36hg18NCBI36
Build 347151,271,503 - 151,570,699NCBI
Celera7146,389,572 - 146,690,258 (-)NCBICelera
Cytogenetic Map7q36.1NCBI
HuRef7145,643,457 - 145,868,582 (-)NCBIHuRef
CHM1_17151,840,538 - 152,142,092 (-)NCBICHM1_1
T2T-CHM13v2.07153,307,815 - 153,608,900 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27151,159,181 - 151,460,261 (-)NCBI
Kmt2c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39525,476,793 - 25,703,853 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl525,476,796 - 25,703,810 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38525,271,795 - 25,498,855 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl525,271,798 - 25,498,783 (-)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv37524,777,612 - 25,004,601 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36524,781,859 - 25,008,848 (-)NCBIMGSCv36mm8
Celera522,207,830 - 22,380,620 (-)NCBICelera
Cytogenetic Map5B1NCBI
cM Map512.35NCBI
Kmt2c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554916,247,249 - 6,402,470 (-)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_0049554916,245,408 - 6,420,535 (-)NCBIChiLan1.0ChiLan1.0
KMT2C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26188,550,082 - 188,851,655 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1740,560,348 - 40,862,006 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07143,714,716 - 144,016,188 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17155,860,699 - 156,081,038 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7155,862,610 - 156,081,043 (-)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1
KMT2C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11615,962,045 - 16,117,601 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1615,963,901 - 16,158,408 (-)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1616,575,056 - 16,858,922 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01617,685,626 - 17,972,552 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.11616,062,320 - 16,346,556 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01616,643,550 - 16,927,359 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01616,694,819 - 16,978,785 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Kmt2c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap12226,698,104 - 226,969,176 (-)NCBImIctTri1.hap1
HiC_Itri_2NW_0244051185,323,045 - 5,592,544 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365277,312,721 - 7,506,365 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365277,310,885 - 7,508,032 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KMT2C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl184,993,227 - 5,278,723 (+)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.1184,993,213 - 5,279,668 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2185,538,409 - 5,587,967 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KMT2C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap121124,775,120 - 125,065,905 (-)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_02366607216,283,079 - 16,504,530 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.121120,299,295 - 120,587,843 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21120,301,188 - 120,587,137 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Kmt2c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248004,510,669 - 4,785,909 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_0046248004,511,549 - 4,784,053 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl

Variants

.
Variants in Kmt2c
4064 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61408Scl23Serum cholesterol level QTL 230.0005blood HDL phospholipid amount (VT:0010504)serum high density lipoprotein phospholipid level (CMO:0001567)4128392287Rat
631209Bw2Body weight QTL24.2retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)4145429897Rat
8552803Bw144Body weight QTL 14416body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)4135396961Rat
8552801Bw143Body weight QTL 1437.3body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)4135396961Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
9589046Scfw2Subcutaneous fat weight QTL 25.540.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)4132668025Rat
8552903Pigfal2Plasma insulin-like growth factor 1 level QTL 27.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)4132668025Rat
724557Plsm1Polydactyly-luxate syndrome (PLS) morphotypes QTL 10.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)4128392287Rat
9590100Sffal4Serum free fatty acids level QTL 47.360.05blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)4132668025Rat
61351Bp33Blood pressure QTL 330.0018arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4128392287Rat
61415Eae11Experimental allergic encephalomyelitis QTL 112.9nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)4140471598Rat
1641905Colcr1Colorectal carcinoma resistance QTL 14.30.0003intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)4842855130449094Rat
1357341Gluco5Glucose level QTL 56.4adipocyte free fatty acid secretion trait (VT:0010465)absolute change in adipocyte free fatty acid secretion per unit volume (CMO:0001446)4134142783Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4588999950889999Rat
1357343Gluco4Glucose level QTL 40.00002adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)4134142783Rat
8552809Vie5Viral induced encephalitis QTL 525.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)4135396961Rat
8552782Vie1Viral induced encephalitis QTL 126.4brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)4135396961Rat
738021Hcar13Hepatocarcinoma resistance QTL 134.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)4133538816Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)4163900697Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4589457557613242Rat
61333Gluco16Glucose level QTL 164.30.00001adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)4131106810Rat
9589097Slep11Serum leptin concentration QTL 115.090.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)4132668025Rat

Markers in Region
RH133147  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.249,833,857 - 9,834,042 (+)MAPPERmRatBN7.2
Rnor_6.046,293,484 - 6,293,668NCBIRnor6.0
Rnor_5.046,314,410 - 6,314,594UniSTSRnor5.0
RGSC_v3.445,238,090 - 5,238,274UniSTSRGSC3.4
Celera4485,694 - 485,878UniSTS
Cytogenetic Map4q11UniSTS
RH139525  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.249,834,444 - 9,834,641 (+)MAPPERmRatBN7.2
Rnor_6.046,294,071 - 6,294,267NCBIRnor6.0
Rnor_5.046,314,997 - 6,315,193UniSTSRnor5.0
RGSC_v3.445,238,677 - 5,238,873UniSTSRGSC3.4
Celera4485,095 - 485,291UniSTS
Cytogenetic Map4q11UniSTS
RH137632  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4q11UniSTS
D7S3202  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.249,834,309 - 9,834,727 (+)MAPPERmRatBN7.2
Rnor_6.046,293,936 - 6,294,353NCBIRnor6.0
Rnor_5.046,314,862 - 6,315,279UniSTSRnor5.0
RGSC_v3.445,238,542 - 5,238,959UniSTSRGSC3.4
Celera4485,009 - 485,426UniSTS
Cytogenetic Map4q11UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
276 154 730 1589 4066 1011 1727 133 874 490 856 156 5388 2589 447 3979 38 1391 738 908 160 158

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_006224786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008762670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008775646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005504104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005504105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010065729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide FQ219148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000010349   ⟹   ENSRNOP00000010349
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl46,282,278 - 6,292,487 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000077289   ⟹   ENSRNOP00000072878
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl46,159,006 - 6,201,526 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093625
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl410,354,551 - 10,568,620 (+)Ensembl
mRatBN7.2 Ensembl49,620,538 - 9,833,539 (+)Ensembl
Rnor_6.0 Ensembl46,083,736 - 6,292,516 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101551   ⟹   ENSRNOP00000089164
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl410,353,735 - 10,568,620 (+)Ensembl
mRatBN7.2 Ensembl49,609,627 - 9,833,539 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103015   ⟹   ENSRNOP00000078989
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl410,354,551 - 10,568,620 (+)Ensembl
mRatBN7.2 Ensembl49,620,487 - 9,833,539 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000108916   ⟹   ENSRNOP00000086031
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl410,354,551 - 10,568,620 (+)Ensembl
mRatBN7.2 Ensembl49,620,634 - 9,833,539 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000157963   ⟹   ENSRNOP00000107839
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl410,353,735 - 10,568,620 (+)Ensembl
RefSeq Acc Id: XM_008762670   ⟹   XP_008760892
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,480 - 10,568,617 (+)NCBI
mRatBN7.249,620,640 - 9,833,088 (+)NCBI
Rnor_6.046,083,650 - 6,294,413 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039108963   ⟹   XP_038964891
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,353,698 - 10,568,617 (+)NCBI
mRatBN7.249,620,640 - 9,834,787 (+)NCBI
RefSeq Acc Id: XM_039108964   ⟹   XP_038964892
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,473 - 10,568,617 (+)NCBI
mRatBN7.249,620,640 - 9,833,088 (+)NCBI
RefSeq Acc Id: XM_039108965   ⟹   XP_038964893
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,480 - 10,568,617 (+)NCBI
mRatBN7.249,620,640 - 9,833,088 (+)NCBI
RefSeq Acc Id: XM_039108966   ⟹   XP_038964894
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,480 - 10,568,617 (+)NCBI
mRatBN7.249,620,640 - 9,833,088 (+)NCBI
RefSeq Acc Id: XM_039108967   ⟹   XP_038964895
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,480 - 10,568,617 (+)NCBI
mRatBN7.249,620,640 - 9,833,088 (+)NCBI
RefSeq Acc Id: XM_039108968   ⟹   XP_038964896
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,387,487 - 10,568,617 (+)NCBI
mRatBN7.249,654,534 - 9,833,088 (+)NCBI
RefSeq Acc Id: XM_039108969   ⟹   XP_038964897
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,480 - 10,568,617 (+)NCBI
mRatBN7.249,620,640 - 9,833,088 (+)NCBI
RefSeq Acc Id: XM_039108970   ⟹   XP_038964898
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,387,487 - 10,568,617 (+)NCBI
mRatBN7.249,654,535 - 9,833,088 (+)NCBI
RefSeq Acc Id: XM_039108971   ⟹   XP_038964899
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,480 - 10,568,617 (+)NCBI
mRatBN7.249,620,640 - 9,833,088 (+)NCBI
RefSeq Acc Id: XM_039108972   ⟹   XP_038964900
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,480 - 10,568,617 (+)NCBI
mRatBN7.249,620,640 - 9,833,088 (+)NCBI
RefSeq Acc Id: XM_039108973   ⟹   XP_038964901
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,480 - 10,568,617 (+)NCBI
mRatBN7.249,620,640 - 9,833,088 (+)NCBI
RefSeq Acc Id: XM_039108978   ⟹   XP_038964906
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,480 - 10,568,617 (+)NCBI
mRatBN7.249,620,640 - 9,833,088 (+)NCBI
RefSeq Acc Id: XM_039108979   ⟹   XP_038964907
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,480 - 10,568,617 (+)NCBI
mRatBN7.249,620,640 - 9,833,088 (+)NCBI
RefSeq Acc Id: XM_039108981   ⟹   XP_038964909
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,478 - 10,544,711 (+)NCBI
mRatBN7.249,620,638 - 9,812,490 (+)NCBI
RefSeq Acc Id: XM_039108982   ⟹   XP_038964910
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,477 - 10,542,815 (+)NCBI
mRatBN7.249,620,638 - 9,807,803 (+)NCBI
RefSeq Acc Id: XM_063286797   ⟹   XP_063142867
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,480 - 10,568,617 (+)NCBI
RefSeq Acc Id: XM_063286798   ⟹   XP_063142868
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,480 - 10,568,617 (+)NCBI
RefSeq Acc Id: XM_063286800   ⟹   XP_063142870
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,473 - 10,568,617 (+)NCBI
RefSeq Acc Id: XM_063286801   ⟹   XP_063142871
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,480 - 10,568,617 (+)NCBI
RefSeq Acc Id: XM_063286802   ⟹   XP_063142872
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,480 - 10,568,617 (+)NCBI
RefSeq Acc Id: XM_063286803   ⟹   XP_063142873
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,480 - 10,568,617 (+)NCBI
RefSeq Acc Id: XM_063286804   ⟹   XP_063142874
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,480 - 10,568,617 (+)NCBI
RefSeq Acc Id: XM_063286805   ⟹   XP_063142875
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,473 - 10,568,617 (+)NCBI
RefSeq Acc Id: XM_063286806   ⟹   XP_063142876
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,353,698 - 10,568,617 (+)NCBI
RefSeq Acc Id: XM_063286807   ⟹   XP_063142877
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,480 - 10,568,617 (+)NCBI
RefSeq Acc Id: XM_063286808   ⟹   XP_063142878
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,480 - 10,568,617 (+)NCBI
RefSeq Acc Id: XM_063286809   ⟹   XP_063142879
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,480 - 10,568,617 (+)NCBI
RefSeq Acc Id: XM_063286810   ⟹   XP_063142880
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,480 - 10,568,617 (+)NCBI
RefSeq Acc Id: XM_063286811   ⟹   XP_063142881
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,480 - 10,568,617 (+)NCBI
RefSeq Acc Id: XR_005504104
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,477 - 10,548,815 (+)NCBI
mRatBN7.249,620,638 - 9,814,979 (+)NCBI
RefSeq Acc Id: XR_005504105
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,477 - 10,548,817 (+)NCBI
mRatBN7.249,620,638 - 9,814,980 (+)NCBI
RefSeq Acc Id: XR_010065729
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,354,477 - 10,755,965 (+)NCBI
Protein Sequences
Protein RefSeqs XP_008760892 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964891 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964892 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964893 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964894 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964895 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964896 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964897 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964898 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964899 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964900 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964901 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964906 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964907 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964909 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964910 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142867 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142868 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142870 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142871 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142872 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142873 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142874 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142875 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142876 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142877 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142878 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142879 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142880 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142881 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000078989
  ENSRNOP00000078989.2
  ENSRNOP00000086031
  ENSRNOP00000086031.2
  ENSRNOP00000089164
  ENSRNOP00000089164.2
  ENSRNOP00000089859
  ENSRNOP00000089859.2
  ENSRNOP00000107839
  ENSRNOP00000107839.1
RefSeq Acc Id: XP_008760892   ⟸   XM_008762670
- Peptide Label: isoform X11
- UniProtKB: A0A8I6A4Z1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072878   ⟸   ENSRNOT00000077289
Ensembl Acc Id: ENSRNOP00000010349   ⟸   ENSRNOT00000010349
RefSeq Acc Id: XP_038964909   ⟸   XM_039108981
- Peptide Label: isoform X26
RefSeq Acc Id: XP_038964910   ⟸   XM_039108982
- Peptide Label: isoform X27
RefSeq Acc Id: XP_038964891   ⟸   XM_039108963
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A4Z1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964897   ⟸   XM_039108969
- Peptide Label: isoform X7
- UniProtKB: A0A8I6A4Z1 (UniProtKB/TrEMBL),   A0ABK0LYY3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964894   ⟸   XM_039108966
- Peptide Label: isoform X5
- UniProtKB: A0A8I6A4Z1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964899   ⟸   XM_039108971
- Peptide Label: isoform X14
- UniProtKB: A0A8I6A4Z1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964893   ⟸   XM_039108965
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A4Z1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964906   ⟸   XM_039108978
- Peptide Label: isoform X22
- UniProtKB: A0A8I6G4C0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964907   ⟸   XM_039108979
- Peptide Label: isoform X25
- UniProtKB: A0A8I6G4C0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964901   ⟸   XM_039108973
- Peptide Label: isoform X19
- UniProtKB: A0A8I6A900 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964900   ⟸   XM_039108972
- Peptide Label: isoform X17
- UniProtKB: A0A8I6A4Z1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964895   ⟸   XM_039108967
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A4Z1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964892   ⟸   XM_039108964
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A4Z1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964896   ⟸   XM_039108968
- Peptide Label: isoform X8
- UniProtKB: A0A8I6A4Z1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964898   ⟸   XM_039108970
- Peptide Label: isoform X10
- UniProtKB: A0A8I6A4Z1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000078989   ⟸   ENSRNOT00000103015
Ensembl Acc Id: ENSRNOP00000086031   ⟸   ENSRNOT00000108916
Ensembl Acc Id: ENSRNOP00000089164   ⟸   ENSRNOT00000101551
RefSeq Acc Id: XP_063142876   ⟸   XM_063286806
- Peptide Label: isoform X20
- UniProtKB: A0A8I6A900 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142870   ⟸   XM_063286800
- Peptide Label: isoform X12
- UniProtKB: A0A8I6A4Z1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142875   ⟸   XM_063286805
- Peptide Label: isoform X20
- UniProtKB: A0A8I6A900 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142873   ⟸   XM_063286803
- Peptide Label: isoform X16
- UniProtKB: A0A8I6A4Z1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142868   ⟸   XM_063286798
- Peptide Label: isoform X9
- UniProtKB: A0A8I6A4Z1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142872   ⟸   XM_063286802
- Peptide Label: isoform X15
- UniProtKB: A0A8I6A4Z1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142879   ⟸   XM_063286809
- Peptide Label: isoform X24
- UniProtKB: A0A8I6G4C0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142878   ⟸   XM_063286808
- Peptide Label: isoform X23
- UniProtKB: A0A8I6G4C0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142880   ⟸   XM_063286810
- Peptide Label: isoform X28
- UniProtKB: A0A8I6A4Z1 (UniProtKB/TrEMBL),   A0A8I6A825 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142877   ⟸   XM_063286807
- Peptide Label: isoform X21
- UniProtKB: A0A8I6A900 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142881   ⟸   XM_063286811
- Peptide Label: isoform X29
- UniProtKB: A0A8I6G4C0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142874   ⟸   XM_063286804
- Peptide Label: isoform X18
- UniProtKB: A0A8I6A4Z1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142867   ⟸   XM_063286797
- Peptide Label: isoform X6
- UniProtKB: A0A8I6A4Z1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142871   ⟸   XM_063286801
- Peptide Label: isoform X13
- UniProtKB: A0A8I6A4Z1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000107839   ⟸   ENSRNOT00000157963
Protein Domains
PHD-type   Post-SET   RING-type   SET

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K426-F1-model_v2 AlphaFold A0A0G2K426 1-738 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1587205 AgrOrtholog
BioCyc Gene G2FUF-46086 BioCyc
Ensembl Genes ENSRNOG00000061080 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000093625 ENTREZGENE
  ENSRNOT00000093625.3 UniProtKB/TrEMBL
  ENSRNOT00000101551 ENTREZGENE
  ENSRNOT00000101551.2 UniProtKB/TrEMBL
  ENSRNOT00000103015 ENTREZGENE
  ENSRNOT00000103015.2 UniProtKB/TrEMBL
  ENSRNOT00000108916 ENTREZGENE
  ENSRNOT00000108916.2 UniProtKB/TrEMBL
  ENSRNOT00000157963 ENTREZGENE
  ENSRNOT00000157963.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.30.10 UniProtKB/TrEMBL
  2.170.270.10 UniProtKB/TrEMBL
  3.30.160.360 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro EPHD UniProtKB/TrEMBL
  FYrich_C UniProtKB/TrEMBL
  FYrich_N UniProtKB/TrEMBL
  HMG_box_dom UniProtKB/TrEMBL
  HMG_box_dom_sf UniProtKB/TrEMBL
  HMGI/Y_DNA-bd_CS UniProtKB/TrEMBL
  KMT2C UniProtKB/TrEMBL
  KMT2C_ePHD1 UniProtKB/TrEMBL
  KMT2C_ePHD2 UniProtKB/TrEMBL
  KMT2C_PHD2 UniProtKB/TrEMBL
  KMT2C_PHD6 UniProtKB/TrEMBL
  Post-SET_dom UniProtKB/TrEMBL
  SET_dom UniProtKB/TrEMBL
  SET_dom_sf UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_PHD UniProtKB/TrEMBL
  Znf_PHD-finger UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene 502710 ENTREZGENE
PANTHER HL01030P-RELATED UniProtKB/TrEMBL
  PTHR45888:SF1 UniProtKB/TrEMBL
Pfam FYRC UniProtKB/TrEMBL
  FYRN UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
  zf-HC5HC2H UniProtKB/TrEMBL
  zf-HC5HC2H_2 UniProtKB/TrEMBL
PhenoGen Kmt2c PhenoGen
PROSITE DHHC UniProtKB/TrEMBL
  EPHD UniProtKB/TrEMBL
  FYRC UniProtKB/TrEMBL
  FYRN UniProtKB/TrEMBL
  HMGI_Y UniProtKB/TrEMBL
  POST_SET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
  ZF_PHD_2 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000061080 RatGTEx
SMART FYRC UniProtKB/TrEMBL
  FYRN UniProtKB/TrEMBL
  HMG UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
  PostSET UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
Superfamily-SCOP SSF47095 UniProtKB/TrEMBL
  SSF57903 UniProtKB/TrEMBL
  SSF82199 UniProtKB/TrEMBL
UniProt A0A8I6A4Z1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A825 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A900 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G4C0 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LYY3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-17 Kmt2c  lysine methyltransferase 2C  Kmt2c  lysine (K)-specific methyltransferase 2C  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-09 Kmt2c  lysine (K)-specific methyltransferase 2C  LOC502710  similar to Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-05-24 LOC502710  similar to Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3)  LOC100364718  myeloid/lymphoid or mixed-lineage leukemia 3-like  Data merged from RGD:2320445 1643240 APPROVED
2010-05-05 LOC100364718  myeloid/lymphoid or mixed-lineage leukemia 3-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-01-09 LOC502710  similar to Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3)  LOC679252  similar to Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3)  Data merged from RGD:1590706 1643240 APPROVED
2006-11-20 LOC679252  similar to Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC502710  similar to Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3)      Symbol and Name status set to provisional 70820 PROVISIONAL