Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Kmt2c (lysine methyltransferase 2C) Rattus norvegicus
Analyze
Symbol: Kmt2c
Name: lysine methyltransferase 2C
Description: Predicted to have histone methyltransferase activity (H3-K4 specific). Predicted to be involved in several processes, including eyelid development in camera-type eye; growth; and positive regulation of fibroblast proliferation. Predicted to localize to the MLL3/4 complex. Human ortholog(s) of this gene implicated in Kleefstra syndrome; esophagus squamous cell carcinoma; and squamous cell carcinoma. Orthologous to human KMT2C (lysine methyltransferase 2C); PARTICIPATES IN DNA modification pathway; histone modification pathway; INTERACTS WITH amphetamine; bisphenol A; dibutyl phthalate.
Type: protein-coding
RefSeq Status: MODEL
Also known as: histone-lysine N-methyltransferase 2C; LOC502710; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C; lysine (K)-specific methyltransferase 2C; myeloid/lymphoid or mixed-lineage leukemia 3-like; similar to Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3)
Orthologs:
Homo sapiens (human) : KMT2C (lysine methyltransferase 2C)  HGNC  Alliance
Mus musculus (house mouse) : Kmt2c (lysine (K)-specific methyltransferase 2C)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kmt2c (lysine methyltransferase 2C)
Pan paniscus (bonobo/pygmy chimpanzee) : KMT2C (lysine methyltransferase 2C)
Canis lupus familiaris (dog) : KMT2C (lysine methyltransferase 2C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kmt2c (lysine methyltransferase 2C)
Sus scrofa (pig) : KMT2C (lysine methyltransferase 2C)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0482,506 - 109,986 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.046,083,650 - 6,294,413 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl46,083,736 - 6,292,516 (+)Ensembl
Rnor_5.0482,826 - 109,979 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.046,104,240 - 6,315,339 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.445,020,018 - 5,239,019 (+)NCBIRGSC3.4rn4RGSC3.4
Celera4484,949 - 698,981 (-)NCBICelera
Cytogenetic Map4q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Kmt2c
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1587205
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.