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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | hepatocellular carcinoma | | ISO | RGD:1342685 | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:28284560 | |
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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | hepatocellular carcinoma | | ISO | RGD:1342685 | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:28284560 | |
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# | Reference Title | Reference Citation |
1. | The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development. | Formstone CJ and Little PF, Mech Dev 2001 Nov;109(1):91-4. |
2. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
3. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
4. | Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening. | Nakayama M, etal., Genomics 1998 Jul 1;51(1):27-34. |
5. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
6. | GOA pipeline | RGD automated data pipeline |
7. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
8. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
9. | Complexes of matrilin-1 and biglycan or decorin connect collagen VI microfibrils to both collagen II and aggrecan. | Wiberg C, etal., J Biol Chem 2003 Sep 26;278(39):37698-704. |
PMID:15778712 | PMID:17618280 | PMID:20473291 | PMID:20631168 | PMID:21106844 | PMID:24305805 |
Celsr3 (Rattus norvegicus - Norway rat) |
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CELSR3 (Homo sapiens - human) |
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Celsr3 (Mus musculus - house mouse) |
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Celsr3 (Chinchilla lanigera - long-tailed chinchilla) |
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CELSR3 (Pan paniscus - bonobo/pygmy chimpanzee) |
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CELSR3 (Canis lupus familiaris - dog) |
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Celsr3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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CELSR3 (Sus scrofa - pig) |
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CELSR3 (Chlorocebus sabaeus - green monkey) |
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Celsr3 (Heterocephalus glaber - naked mole-rat) |
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BF386320 |
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BF406162 |
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Celsr3 |
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The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 64 | ||||||||||||
Low | 2 | 10 | 2 | 2 | 10 | 25 | |||||||
Below cutoff | 3 | 38 | 20 | 17 | 8 | 17 | 8 | 8 | 13 | 16 | 10 | 8 |
RefSeq Transcripts | NM_031320 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_006243860 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006243861 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017595932 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039082204 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039082205 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XR_005487932 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XR_005487933 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XR_005487934 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XR_005487935 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AB011528 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
AC096455 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH473954 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JACYVU010000200 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000084220 ⟹ ENSRNOP00000068821 | ||||||||||||
RefSeq Status: | |||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000112823 ⟹ ENSRNOP00000079747 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000118398 ⟹ ENSRNOP00000085264 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_031320 ⟹ NP_112610 | ||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006243860 ⟹ XP_006243922 | ||||||||||||||||
RefSeq Status: | |||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006243861 ⟹ XP_006243923 | ||||||||||||||||
RefSeq Status: | |||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_017595932 ⟹ XP_017451421 | ||||||||||||
RefSeq Status: | |||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039082204 ⟹ XP_038938132 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_039082205 ⟹ XP_038938133 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XR_005487932 | ||||||||
RefSeq Status: | |||||||||
Type: | NON-CODING | ||||||||
Position: |
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RefSeq Acc Id: | XR_005487933 | ||||||||
RefSeq Status: | |||||||||
Type: | NON-CODING | ||||||||
Position: |
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RefSeq Acc Id: | XR_005487934 | ||||||||
RefSeq Status: | |||||||||
Type: | NON-CODING | ||||||||
Position: |
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RefSeq Acc Id: | XR_005487935 | ||||||||
RefSeq Status: | |||||||||
Type: | NON-CODING | ||||||||
Position: |
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Protein RefSeqs | NP_112610 | (Get FASTA) | NCBI Sequence Viewer |
XP_006243922 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006243923 | (Get FASTA) | NCBI Sequence Viewer | |
XP_017451421 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038938132 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038938133 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | BAA32459 | (Get FASTA) | NCBI Sequence Viewer |
EDL77136 | (Get FASTA) | NCBI Sequence Viewer | |
O88278 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_112610 ⟸ NM_031320 |
- Peptide Label: | precursor |
- UniProtKB: | O88278 (UniProtKB/Swiss-Prot) |
- Sequence: |
RefSeq Acc Id: | XP_006243922 ⟸ XM_006243860 |
- Peptide Label: | isoform X1 |
- Sequence: |
RefSeq Acc Id: | XP_006243923 ⟸ XM_006243861 |
- Peptide Label: | isoform X5 |
- Sequence: |
RefSeq Acc Id: | XP_017451421 ⟸ XM_017595932 |
- Peptide Label: | isoform X4 |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000068821 ⟸ ENSRNOT00000084220 |
RefSeq Acc Id: | XP_038938132 ⟸ XM_039082204 |
- Peptide Label: | isoform X2 |
RefSeq Acc Id: | XP_038938133 ⟸ XM_039082205 |
- Peptide Label: | isoform X3 |
RefSeq Acc Id: | ENSRNOP00000085264 ⟸ ENSRNOT00000118398 |
RefSeq Acc Id: | ENSRNOP00000079747 ⟸ ENSRNOT00000112823 |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
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Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
8 | 117622745 | 117622746 | G | A | snv | BBDP/Wor (RGD) |
8 | 117622825 | 117622826 | C | G | snv | BXH3/CubMcwi (2020) |
8 | 117632199 | 117632200 | G | A | snv | WKY/NCrl (RGD) |
Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
8 | 116967049 | 116967050 | G | A | snv | BBDP/WorN (KNAW) |
8 | 116976503 | 116976504 | G | A | snv | WKY/NCrl (KNAW) |
Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
8 | 109533149 | 109533150 | C | G | snv | BXH3/CubMcwi (2020) |
Database | Acc Id | Source(s) |
AGR Gene | RGD:621787 | AgrOrtholog |
BioCyc Gene | G2FUF-29112 | BioCyc |
Ensembl Genes | ENSRNOG00000053889 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Ensembl Protein | ENSRNOP00000068821 | ENTREZGENE |
ENSRNOP00000079747 | ENTREZGENE, UniProtKB/Swiss-Prot | |
ENSRNOP00000085264 | ENTREZGENE | |
ENSRNOP00000085264.1 | UniProtKB/TrEMBL | |
Ensembl Transcript | ENSRNOT00000084220 | ENTREZGENE |
ENSRNOT00000112823 | ENTREZGENE, UniProtKB/Swiss-Prot | |
ENSRNOT00000118398 | ENTREZGENE | |
ENSRNOT00000118398.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | 2.60.220.50 | UniProtKB/Swiss-Prot |
4.10.1240.10 | UniProtKB/Swiss-Prot | |
InterPro | Cadherin-like_dom | UniProtKB/Swiss-Prot |
Cadherin-like_sf | UniProtKB/Swiss-Prot | |
Cadherin_CS | UniProtKB/Swiss-Prot | |
ConA-like_dom_sf | UniProtKB/Swiss-Prot | |
EGF-like_Ca-bd_dom | UniProtKB/Swiss-Prot | |
EGF-like_dom | UniProtKB/Swiss-Prot | |
GAIN_dom_N | UniProtKB/Swiss-Prot | |
GAIN_dom_sf | UniProtKB/Swiss-Prot | |
GPCR_2-like | UniProtKB/Swiss-Prot | |
GPCR_2_extracell_dom_sf | UniProtKB/Swiss-Prot | |
GPCR_2_extracellular_dom | UniProtKB/Swiss-Prot | |
GPCR_2_secretin-like | UniProtKB/Swiss-Prot | |
GPCR_2_secretin-like_CS | UniProtKB/Swiss-Prot | |
GPS | UniProtKB/Swiss-Prot | |
Laminin_EGF | UniProtKB/Swiss-Prot | |
Laminin_G | UniProtKB/Swiss-Prot | |
KEGG Report | rno:83466 | UniProtKB/Swiss-Prot |
NCBI Gene | 83466 | ENTREZGENE |
Pfam | 7tm_2 | UniProtKB/Swiss-Prot |
Cadherin | UniProtKB/Swiss-Prot | |
EGF | UniProtKB/Swiss-Prot | |
GAIN | UniProtKB/Swiss-Prot | |
HRM | UniProtKB/Swiss-Prot | |
Laminin_EGF | UniProtKB/Swiss-Prot | |
Laminin_G_2 | UniProtKB/Swiss-Prot | |
PhenoGen | Celsr3 | PhenoGen |
PRINTS | CADHERIN | UniProtKB/Swiss-Prot |
GPCRSECRETIN | UniProtKB/Swiss-Prot | |
PROSITE | ASX_HYDROXYL | UniProtKB/Swiss-Prot |
CADHERIN_1 | UniProtKB/Swiss-Prot | |
CADHERIN_2 | UniProtKB/Swiss-Prot | |
EGF_1 | UniProtKB/Swiss-Prot | |
EGF_2 | UniProtKB/Swiss-Prot | |
EGF_3 | UniProtKB/Swiss-Prot | |
EGF_LAM_1 | UniProtKB/Swiss-Prot | |
EGF_LAM_2 | UniProtKB/Swiss-Prot | |
G_PROTEIN_RECEP_F2_2 | UniProtKB/Swiss-Prot | |
G_PROTEIN_RECEP_F2_3 | UniProtKB/Swiss-Prot | |
G_PROTEIN_RECEP_F2_4 | UniProtKB/Swiss-Prot | |
GPS | UniProtKB/Swiss-Prot | |
LAM_G_DOMAIN | UniProtKB/Swiss-Prot | |
SMART | EGF | UniProtKB/Swiss-Prot |
EGF_CA | UniProtKB/Swiss-Prot | |
EGF_Lam | UniProtKB/Swiss-Prot | |
GPS | UniProtKB/Swiss-Prot | |
HormR | UniProtKB/Swiss-Prot | |
LamG | UniProtKB/Swiss-Prot | |
SM00112 | UniProtKB/Swiss-Prot | |
Superfamily-SCOP | SSF111418 | UniProtKB/Swiss-Prot |
SSF49313 | UniProtKB/Swiss-Prot | |
SSF49899 | UniProtKB/Swiss-Prot | |
UniProt | A0A8I6A2Y0_RAT | UniProtKB/TrEMBL |
CELR3_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2013-02-27 | Celsr3 | cadherin, EGF LAG seven-pass G-type receptor 3 | Celsr3 | cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-04-25 | Celsr3 | cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila) | Celsr3 | cadherin EGF LAG seven-pass G-type receptor 3 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2005-01-20 | Celsr3 | cadherin EGF LAG seven-pass G-type receptor 3 | Symbol and Name status set to approved | 1299863 | APPROVED | ||
2002-08-07 | Celsr3 | cadherin EGF LAG seven-pass G-type receptor 3 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
Note Type | Note | Reference |
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gene_domains | contains multiple EGF-like motifs | 68762 |