Celsr3 (cadherin, EGF LAG seven-pass G-type receptor 3) - Rat Genome Database

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Gene: Celsr3 (cadherin, EGF LAG seven-pass G-type receptor 3) Rattus norvegicus
Analyze
Symbol: Celsr3
Name: cadherin, EGF LAG seven-pass G-type receptor 3
RGD ID: 621787
Description: Predicted to enable G protein-coupled receptor activity and calcium ion binding activity. Predicted to be involved in Wnt signaling pathway, planar cell polarity pathway; axon guidance; and cell-cell adhesion. Predicted to act upstream of or within several processes, including cilium assembly; generation of neurons; and regulation of protein phosphorylation. Predicted to be located in plasma membrane. Predicted to be active in glutamatergic synapse; postsynaptic density membrane; and presynaptic active zone membrane. Orthologous to human CELSR3 (cadherin EGF LAG seven-pass G-type receptor 3); INTERACTS WITH ammonium chloride; atrazine; bis(2-ethylhexyl) phthalate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cadherin EGF LAG seven-pass G-type receptor 3; cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila); Megf2; multiple EGF-like domains protein 2; multiple epidermal growth factor-like domains 2; multiple epidermal growth factor-like domains protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,409,136 - 118,438,593 (+)NCBIGRCr8
mRatBN7.28109,530,597 - 109,558,360 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8109,530,641 - 109,558,354 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8115,148,091 - 115,175,780 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,347,270 - 113,374,959 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08111,190,068 - 111,217,758 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08117,620,293 - 117,648,034 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,620,317 - 117,648,028 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08116,964,621 - 116,991,771 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48113,882,883 - 113,923,950 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18113,902,337 - 113,943,405 (+)NCBI
Celera8108,824,695 - 108,852,099 (+)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development. Formstone CJ and Little PF, Mech Dev 2001 Nov;109(1):91-4.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening. Nakayama M, etal., Genomics 1998 Jul 1;51(1):27-34.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Complexes of matrilin-1 and biglycan or decorin connect collagen VI microfibrils to both collagen II and aggrecan. Wiberg C, etal., J Biol Chem 2003 Sep 26;278(39):37698-704.
Additional References at PubMed
PMID:15778712   PMID:17618280   PMID:20473291   PMID:20631168   PMID:21106844   PMID:24305805  


Genomics

Comparative Map Data
Celsr3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,409,136 - 118,438,593 (+)NCBIGRCr8
mRatBN7.28109,530,597 - 109,558,360 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8109,530,641 - 109,558,354 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8115,148,091 - 115,175,780 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,347,270 - 113,374,959 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08111,190,068 - 111,217,758 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08117,620,293 - 117,648,034 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,620,317 - 117,648,028 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08116,964,621 - 116,991,771 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48113,882,883 - 113,923,950 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18113,902,337 - 113,943,405 (+)NCBI
Celera8108,824,695 - 108,852,099 (+)NCBICelera
Cytogenetic Map8q32NCBI
CELSR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38348,636,463 - 48,662,886 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl348,636,463 - 48,662,886 (-)EnsemblGRCh38hg38GRCh38
GRCh37348,673,896 - 48,700,319 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36348,648,900 - 48,675,352 (-)NCBINCBI36Build 36hg18NCBI36
Build 34348,648,900 - 48,675,352NCBI
Celera348,629,806 - 48,656,257 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef348,732,066 - 48,758,302 (-)NCBIHuRef
CHM1_1348,626,190 - 48,652,451 (-)NCBICHM1_1
T2T-CHM13v2.0348,665,423 - 48,691,846 (-)NCBIT2T-CHM13v2.0
Celsr3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399108,703,244 - 108,730,168 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9108,703,519 - 108,730,168 (+)EnsemblGRCm39 Ensembl
GRCm389108,826,023 - 108,852,969 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,826,320 - 108,852,969 (+)EnsemblGRCm38mm10GRCm38
MGSCv379108,728,651 - 108,755,300 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369108,683,543 - 108,710,186 (+)NCBIMGSCv36mm8
Celera9108,433,487 - 108,460,140 (+)NCBICelera
Cytogenetic Map9F2NCBI
cM Map959.63NCBI
Celsr3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955532725,243 - 749,173 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955532724,306 - 749,192 (-)NCBIChiLan1.0ChiLan1.0
CELSR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2248,610,805 - 48,639,012 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1348,615,573 - 48,643,236 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0348,557,976 - 48,586,051 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1349,639,936 - 49,667,335 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl349,639,942 - 49,667,335 (-)Ensemblpanpan1.1panPan2
CELSR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12040,457,430 - 40,495,128 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2040,457,657 - 40,483,881 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2040,375,514 - 40,412,346 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02040,943,952 - 40,980,477 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2040,970,510 - 40,980,478 (+)EnsemblROS_Cfam_1.0 Ensembl
ROS_Cfam_1.0 Ensembl2040,943,706 - 40,966,371 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12040,181,313 - 40,217,932 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02040,585,605 - 40,622,438 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02040,867,118 - 40,903,641 (+)NCBIUU_Cfam_GSD_1.0
Celsr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560263,676,979 - 63,703,515 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936529437,418 - 464,017 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936529437,476 - 464,012 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CELSR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1331,331,574 - 31,357,469 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11331,331,563 - 31,357,374 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21334,595,206 - 34,637,678 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CELSR3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12210,046,361 - 10,073,689 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2210,045,900 - 10,072,395 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041157,017,459 - 157,043,000 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Celsr3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247302,651,756 - 2,675,923 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247302,650,096 - 2,675,930 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Celsr3
135 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:277
Count of miRNA genes:149
Interacting mature miRNAs:187
Transcripts:ENSRNOT00000040661
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8100149864120994388Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088626Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)895718998123900184Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)889265192114019816Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat

Markers in Region
BF386320  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,528,642 - 109,528,814 (+)MAPPERmRatBN7.2
Rnor_6.08117,618,319 - 117,618,490NCBIRnor6.0
Rnor_5.08116,962,623 - 116,962,794UniSTSRnor5.0
RGSC_v3.48113,880,885 - 113,881,056UniSTSRGSC3.4
Celera8108,822,697 - 108,822,868UniSTS
RH 3.4 Map81115.79UniSTS
Cytogenetic Map8q32UniSTS
BF406162  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,528,704 - 109,528,872 (+)MAPPERmRatBN7.2
Rnor_6.08117,618,381 - 117,618,548NCBIRnor6.0
Rnor_5.08116,962,685 - 116,962,852UniSTSRnor5.0
RGSC_v3.48113,880,947 - 113,881,114UniSTSRGSC3.4
Celera8108,822,759 - 108,822,926UniSTS
RH 3.4 Map81114.89UniSTS
Cytogenetic Map8q32UniSTS
Celsr3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,551,665 - 109,552,479 (+)MAPPERmRatBN7.2
Rnor_6.08117,641,340 - 117,642,153NCBIRnor6.0
Rnor_5.08116,985,078 - 116,985,891UniSTSRnor5.0
RGSC_v3.48113,917,263 - 113,918,076UniSTSRGSC3.4
Celera8108,845,413 - 108,846,226UniSTS
Cytogenetic Map8q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 8 46 113 61 59 34 13 34 6 150 79 93 20 60 25

Sequence


Ensembl Acc Id: ENSRNOT00000084220   ⟹   ENSRNOP00000068821
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8109,530,641 - 109,558,354 (+)Ensembl
Rnor_6.0 Ensembl8117,620,317 - 117,648,028 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112823   ⟹   ENSRNOP00000079747
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8109,530,641 - 109,558,354 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118398   ⟹   ENSRNOP00000085264
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8109,530,641 - 109,554,996 (+)Ensembl
RefSeq Acc Id: NM_031320   ⟹   NP_112610
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,409,136 - 118,436,847 (+)NCBI
mRatBN7.28109,530,641 - 109,558,354 (+)NCBI
Rnor_6.08117,620,317 - 117,648,028 (+)NCBI
Rnor_5.08116,964,621 - 116,991,771 (+)NCBI
RGSC_v3.48113,882,883 - 113,923,950 (+)RGD
Celera8108,824,695 - 108,852,099 (+)RGD
Sequence:
RefSeq Acc Id: XM_006243860   ⟹   XP_006243922
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,409,404 - 118,438,593 (+)NCBI
mRatBN7.28109,530,603 - 109,558,360 (+)NCBI
Rnor_6.08117,620,296 - 117,648,034 (+)NCBI
Rnor_5.08116,964,621 - 116,991,771 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006243861   ⟹   XP_006243923
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,409,404 - 118,429,365 (+)NCBI
mRatBN7.28109,530,603 - 109,550,732 (+)NCBI
Rnor_6.08117,620,293 - 117,640,496 (+)NCBI
Rnor_5.08116,964,621 - 116,991,771 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039082204   ⟹   XP_038938132
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,409,404 - 118,438,593 (+)NCBI
mRatBN7.28109,530,603 - 109,558,360 (+)NCBI
RefSeq Acc Id: XM_039082205   ⟹   XP_038938133
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,409,404 - 118,438,593 (+)NCBI
mRatBN7.28109,530,603 - 109,558,360 (+)NCBI
RefSeq Acc Id: XM_063266218   ⟹   XP_063122288
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,409,404 - 118,429,853 (+)NCBI
RefSeq Acc Id: XR_005487934
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,409,404 - 118,422,390 (+)NCBI
mRatBN7.28109,530,597 - 109,543,898 (+)NCBI
RefSeq Acc Id: XR_005487935
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,409,404 - 118,424,282 (+)NCBI
mRatBN7.28109,530,597 - 109,545,787 (+)NCBI
RefSeq Acc Id: XR_010054036
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,409,404 - 118,430,209 (+)NCBI
RefSeq Acc Id: NP_112610   ⟸   NM_031320
- Peptide Label: precursor
- UniProtKB: O88278 (UniProtKB/Swiss-Prot),   A0A8L2R1D5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243922   ⟸   XM_006243860
- Peptide Label: isoform X1
- UniProtKB: A0A8L2R1D5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243923   ⟸   XM_006243861
- Peptide Label: isoform X5
- UniProtKB: A6I391 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000068821   ⟸   ENSRNOT00000084220
RefSeq Acc Id: XP_038938132   ⟸   XM_039082204
- Peptide Label: isoform X2
- UniProtKB: A0A8L2R1D5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938133   ⟸   XM_039082205
- Peptide Label: isoform X3
- UniProtKB: A0A8L2R1D5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000085264   ⟸   ENSRNOT00000118398
Ensembl Acc Id: ENSRNOP00000079747   ⟸   ENSRNOT00000112823
RefSeq Acc Id: XP_063122288   ⟸   XM_063266218
- Peptide Label: isoform X4
- UniProtKB: A6I391 (UniProtKB/TrEMBL)
Protein Domains
Cadherin   EGF-like   G-protein coupled receptors family 2 profile   GAIN-B   Laminin EGF-like   Laminin G   Laminin G-like

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621787 AgrOrtholog
BioCyc Gene G2FUF-29112 BioCyc
Ensembl Genes ENSRNOG00000053889 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055007121 UniProtKB/Swiss-Prot
  ENSRNOG00060016910 UniProtKB/Swiss-Prot
  ENSRNOG00065006816 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000084220.2 UniProtKB/TrEMBL
  ENSRNOT00000112823.1 UniProtKB/Swiss-Prot
  ENSRNOT00000118398.1 UniProtKB/TrEMBL
  ENSRNOT00055011835 UniProtKB/Swiss-Prot
  ENSRNOT00060028987 UniProtKB/Swiss-Prot
  ENSRNOT00065010630 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.120.200 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.220.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  4.10.1240.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cadherins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Laminin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cadherin-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cadherin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cadherin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GAIN_dom_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GAIN_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2_extracell_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2_extracellular_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2_secretin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2_secretin-like_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/Swiss-Prot
  Laminin_G UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LE_dom UniProtKB/TrEMBL
KEGG Report rno:83466 UniProtKB/Swiss-Prot
NCBI Gene 83466 ENTREZGENE
PANTHER CADHERIN EGF LAG SEVEN-PASS G-TYPE RECEPTOR 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FAT ATYPICAL CADHERIN-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cadherin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Laminin_G_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Celsr3 PhenoGen
PRINTS CADHERIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCRSECRETIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/Swiss-Prot
  CADHERIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CADHERIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_LAM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_LAM_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LAM_G_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000053889 RatGTEx
  ENSRNOG00055007121 RatGTEx
  ENSRNOG00060016910 RatGTEx
  ENSRNOG00065006816 RatGTEx
SMART EGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_CA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_Lam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HormR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LamG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF111418 UniProtKB/Swiss-Prot
  SSF49313 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49899 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A2Y0_RAT UniProtKB/TrEMBL
  A0A8L2R1D5 ENTREZGENE, UniProtKB/TrEMBL
  A6I391 ENTREZGENE, UniProtKB/TrEMBL
  CELR3_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-02-27 Celsr3  cadherin, EGF LAG seven-pass G-type receptor 3  Celsr3  cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-25 Celsr3  cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)  Celsr3  cadherin EGF LAG seven-pass G-type receptor 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Celsr3  cadherin EGF LAG seven-pass G-type receptor 3      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Celsr3  cadherin EGF LAG seven-pass G-type receptor 3      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains multiple EGF-like motifs 68762